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93da28f7330e7fc3b0b67a94b1f24c05bf42d3d1
wikidoc
ACP1
ACP1 Low molecular weight phosphotyrosine protein phosphatase is an enzyme that in humans is encoded by the ACP1 gene. The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine ph...
ACP1 Low molecular weight phosphotyrosine protein phosphatase is an enzyme that in humans is encoded by the ACP1 gene. The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine p...
https://www.wikidoc.org/index.php/ACP1
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wikidoc
ADAR
ADAR Double-stranded RNA-specific adenosine deaminase is an enzyme that in humans is encoded by the ADAR gene (which stands for adenosine deaminase acting on RNA). Adenosine deaminases acting on RNA (ADAR) are enzymes responsible for binding to double stranded RNA (dsRNA) and converting adenosine (A) to inosine (I) by ...
ADAR Double-stranded RNA-specific adenosine deaminase is an enzyme that in humans is encoded by the ADAR gene (which stands for adenosine deaminase acting on RNA).[1][2] Adenosine deaminases acting on RNA (ADAR) are enzymes responsible for binding to double stranded RNA (dsRNA) and converting adenosine (A) to inosine ...
https://www.wikidoc.org/index.php/ADAR
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wikidoc
ADD2
ADD2 Beta-adducin is a protein that in humans is encoded by the ADD2 gene. # Function Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta, and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the as...
ADD2 Beta-adducin is a protein that in humans is encoded by the ADD2 gene.[1][2] # Function Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta, and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in...
https://www.wikidoc.org/index.php/ADD2
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wikidoc
ADH5
ADH5 Alcohol dehydrogenase class-3 is an enzyme that in humans is encoded by the ADH5 gene. This gene encodes glutathione-dependent formaldehyde dehydrogenase or the class III alcohol dehydrogenase chi subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of su...
ADH5 Alcohol dehydrogenase class-3 is an enzyme that in humans is encoded by the ADH5 gene.[1][2][3] This gene encodes glutathione-dependent formaldehyde dehydrogenase or the class III alcohol dehydrogenase chi subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide var...
https://www.wikidoc.org/index.php/ADH5
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wikidoc
ADME
ADME # Overview ADME is an acronym in pharmacokinetics and pharmacology for absorption, distribution, metabolism, and excretion, and describes the disposition of a pharmaceutical compound within an organism. The four criteria all influence the drug levels and kinetics of drug exposure to the tissues and hence influenc...
ADME # Overview ADME is an acronym in pharmacokinetics and pharmacology for absorption, distribution, metabolism, and excretion, and describes the disposition of a pharmaceutical compound within an organism. The four criteria all influence the drug levels and kinetics of drug exposure to the tissues and hence influenc...
https://www.wikidoc.org/index.php/ADME
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wikidoc
AGR2
AGR2 Anterior gradient protein 2 homolog (AGR-2), also known as secreted cement gland protein XAG-2 homolog, is a protein that in humans is encoded by the AGR2 gene. Anterior gradient homolog 2 was originally discovered in Xenopus laevis. In Xenopus AGR2 plays a role in cement gland differentiation, but in human cancer...
AGR2 Anterior gradient protein 2 homolog (AGR-2), also known as secreted cement gland protein XAG-2 homolog, is a protein that in humans is encoded by the AGR2 gene. Anterior gradient homolog 2 was originally discovered in Xenopus laevis.[1] In Xenopus AGR2 plays a role in cement gland differentiation,[2] but in human...
https://www.wikidoc.org/index.php/AGR2
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wikidoc
AIM2
AIM2 Interferon-inducible protein AIM2 also known as absent in melanoma 2 or simply AIM2 is a protein that in humans is encoded by the AIM2 gene. Recent research has shown that AIM2 is part of the inflammasome and contributes to the defence against bacterial and viral DNA. # Structure AIM2 is a 343 amino acid protein ...
AIM2 Interferon-inducible protein AIM2 also known as absent in melanoma 2 or simply AIM2 is a protein that in humans is encoded by the AIM2 gene.[1][2] Recent research has shown that AIM2 is part of the inflammasome and contributes to the defence against bacterial and viral DNA.[3] # Structure AIM2 is a 343 amino aci...
https://www.wikidoc.org/index.php/AIM2
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wikidoc
AKT1
AKT1 RAC-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) domains. It is commonly referred to as PKB, or by both names as "Akt/PKB". # Function The serine-threonine ...
AKT1 RAC-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) domains.[1] It is commonly referred to as PKB, or by both names as "Akt/PKB". # Function The serine-threon...
https://www.wikidoc.org/index.php/AKT1
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wikidoc
AKT2
AKT2 RAC-beta serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT2 gene. # Function This gene is a putative oncogene encoding a protein belonging to the AKT subfamily of serine/threonine kinases that contain SH2-like (Src homology 2-like) domains. The encoded protein is a general protein...
AKT2 RAC-beta serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT2 gene.[1] # Function This gene is a putative oncogene encoding a protein belonging to the AKT subfamily of serine/threonine kinases that contain SH2-like (Src homology 2-like) domains. The encoded protein is a general pro...
https://www.wikidoc.org/index.php/AKT2
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wikidoc
ALG2
ALG2 Alpha-1,3-mannosyltransferase ALG2 is an enzyme that is encoded by the ALG2 gene. Mutations in the human gene are associated with congenital defects in glycosylation # Function This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosyla...
ALG2 Alpha-1,3-mannosyltransferase ALG2 is an enzyme that is encoded by the ALG2 gene.[1] Mutations in the human gene are associated with congenital defects in glycosylation [2][3] # Function This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase,...
https://www.wikidoc.org/index.php/ALG2
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wikidoc
ALPL
ALPL Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene. # Function There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue-nonspecific). The first three are located together on chromo...
ALPL Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene.[1][2] # Function There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue-nonspecific). The first three are located together on...
https://www.wikidoc.org/index.php/ALPL
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wikidoc
ALX1
ALX1 ALX homeobox protein 1 is a protein that in humans is encoded by the ALX1 gene. # Function The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mo...
ALX1 ALX homeobox protein 1 is a protein that in humans is encoded by the ALX1 gene.[1][2][3] # Function The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations...
https://www.wikidoc.org/index.php/ALX1
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wikidoc
ALX3
ALX3 The ALX3 gene, also known as aristaless-like homeobox 3, is a protein coding gene that provides instructions to build a protein which is a member of the homeobox protein family. This grouping regulates patterns of anatomical development. The gene encodes a nuclear protein that functions as a transcription regulato...
ALX3 The ALX3 gene, also known as aristaless-like homeobox 3, is a protein coding gene that provides instructions to build a protein which is a member of the homeobox protein family.[1] This grouping regulates patterns of anatomical development. The gene encodes a nuclear protein that functions as a transcription regu...
https://www.wikidoc.org/index.php/ALX3
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wikidoc
AMBN
AMBN Ameloblastin (enamel matrix protein) is a protein that in humans is encoded by the AMBN gene. # Function Ameloblastin, also known as amelin, is a gene-specific protein found in tooth enamel. Although less than 5% of enamel consists of protein, ameloblastins comprise 5–10% of all enamel protein. This protein is fo...
AMBN Ameloblastin (enamel matrix protein) is a protein that in humans is encoded by the AMBN gene.[1] # Function Ameloblastin, also known as amelin, is a gene-specific protein found in tooth enamel. Although less than 5% of enamel consists of protein, ameloblastins comprise 5–10% of all enamel protein. This protein i...
https://www.wikidoc.org/index.php/AMBN
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wikidoc
AMFR
AMFR Autocrine motility factor receptor, isoform 2 is a protein that in humans is encoded by the AMFR gene. Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. Th...
AMFR Autocrine motility factor receptor, isoform 2 is a protein that in humans is encoded by the AMFR gene.[1][2] Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility fac...
https://www.wikidoc.org/index.php/AMFR
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wikidoc
ANK1
ANK1 Ankyrin 1, erythrocytic, also known as ANK1, is a protein that in humans is encoded by the ANK1 gene. # Tissue distribution The protein encoded by this gene, Ankyrin 1, is the prototype of the ankyrin family, was first discovered in erythrocytes, but since has also been found in brain and muscles. # Genetics Com...
ANK1 Ankyrin 1, erythrocytic, also known as ANK1, is a protein that in humans is encoded by the ANK1 gene.[1][2] # Tissue distribution The protein encoded by this gene, Ankyrin 1, is the prototype of the ankyrin family, was first discovered in erythrocytes, but since has also been found in brain and muscles.[2] # Ge...
https://www.wikidoc.org/index.php/ANK1
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wikidoc
ANK2
ANK2 Ankyrin-B, also known as Ankyrin-2, is a protein which in humans is encoded by the ANK2 gene. Ankyrin-B is ubiquitously expressed, but shows high expression in cardiac muscle. Ankyrin-B plays an essential role in the localization and membrane stabilization of ion transporters and ion channels in cardiomyocytes, as...
ANK2 Ankyrin-B, also known as Ankyrin-2, is a protein which in humans is encoded by the ANK2 gene.[1][2] Ankyrin-B is ubiquitously expressed, but shows high expression in cardiac muscle. Ankyrin-B plays an essential role in the localization and membrane stabilization of ion transporters and ion channels in cardiomyocy...
https://www.wikidoc.org/index.php/ANK2
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wikidoc
ANK3
ANK3 Ankyrin-3 (ANK-3), also known as ankyrin-G, is a protein from ankyrin family that in humans is encoded by the ANK3 gene. # Function The protein encoded by this gene, ankyrin-3 is an immunologically distinct gene product from ankyrins ANK1 and ANK2, and was originally found at the axonal initial segment and nodes...
ANK3 Ankyrin-3 (ANK-3), also known as ankyrin-G, is a protein from ankyrin family that in humans is encoded by the ANK3 gene.[1][2] # Function The protein encoded by this gene, ankyrin-3 is an immunologically distinct gene product from ankyrins ANK1 and ANK2, and was originally found at the axonal initial segment an...
https://www.wikidoc.org/index.php/ANK3
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wikidoc
ANLN
ANLN Anillin is a conserved protein implicated in cytoskeletal dynamics during cellularization and cytokinesis. The ANLN gene in humans and the scraps gene in Drosophila encode Anillin. In 1989, anillin was first isolated in embryos of Drosophila melanogaster. It was identified as an F-actin binding protein. Six years ...
ANLN Anillin is a conserved protein implicated in cytoskeletal dynamics during cellularization and cytokinesis. The ANLN gene in humans and the scraps gene in Drosophila encode Anillin.[1] In 1989, anillin was first isolated in embryos of Drosophila melanogaster. It was identified as an F-actin binding protein.[2] Six...
https://www.wikidoc.org/index.php/ANLN
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wikidoc
ANO1
ANO1 Anoctamin-1 (ANO1) also known as Transmembrane member 16A (TMEM16A) is a protein that, in humans, is encoded by the ANO1 gene. Anoctamin-1 is a voltage-sensitive calcium-activated chloride channel that is expressed in smooth muscle and epithelial cells; it is highly expressed in human interstitial cells of Cajal (...
ANO1 Anoctamin-1 (ANO1) also known as Transmembrane member 16A (TMEM16A) is a protein that, in humans, is encoded by the ANO1 gene.[1][2] Anoctamin-1 is a voltage-sensitive calcium-activated chloride channel that is expressed in smooth muscle and epithelial cells;[3] it is highly expressed in human interstitial cells ...
https://www.wikidoc.org/index.php/ANO1
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wikidoc
AOAH
AOAH Acyloxyacyl hydrolase, also known as AOAH, is a protein which in humans is encoded by the AOAH gene. # Function Acyloxyacyl hydrolase (AOAH) is a 2-subunit lipase which selectively hydrolyzes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (LPSs, also ...
AOAH Acyloxyacyl hydrolase, also known as AOAH, is a protein which in humans is encoded by the AOAH gene. # Function Acyloxyacyl hydrolase (AOAH) is a 2-subunit lipase which selectively hydrolyzes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (LPSs, also...
https://www.wikidoc.org/index.php/AOAH
d5da0f09b180159adc10d8fa35854b3c46ff511c
wikidoc
AOC3
AOC3 Amine oxidase, copper containing 3, also known as vascular adhesion protein (VAP-1) and HPAO is an enzyme that in humans is encoded by the AOC3 gene on chromosome 17. This protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family and is associated with many vascular diseases. # Structure VAP-...
AOC3 Amine oxidase, copper containing 3, also known as vascular adhesion protein (VAP-1) and HPAO is an enzyme that in humans is encoded by the AOC3 gene on chromosome 17. This protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family and is associated with many vascular diseases.[1] # Structure ...
https://www.wikidoc.org/index.php/AOC3
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wikidoc
ARAF
ARAF Serine/threonine-protein kinase A-Raf or simply A-Raf is an enzyme that in humans is encoded by the ARAF gene. A-Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases. Compared to the other members of this family (Raf-1 and B-Raf), very little is known about A-Raf. It seems to shar...
ARAF Serine/threonine-protein kinase A-Raf or simply A-Raf is an enzyme that in humans is encoded by the ARAF gene.[1] A-Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases.[2] Compared to the other members of this family (Raf-1 and B-Raf), very little is known about A-Raf. It seems ...
https://www.wikidoc.org/index.php/ARAF
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wikidoc
ARF1
ARF1 ADP-ribosylation factor 1 is a protein that in humans is encoded by the ARF1 gene. # Function ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play ...
ARF1 ADP-ribosylation factor 1 is a protein that in humans is encoded by the ARF1 gene.[1] # Function ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and p...
https://www.wikidoc.org/index.php/ARF1
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wikidoc
ARF4
ARF4 ADP-ribosylation factor 4 is a protein that in humans is encoded by the ARF4 gene. # Function ADP-ribosylation factor 4 (ARF4) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role ...
ARF4 ADP-ribosylation factor 4 is a protein that in humans is encoded by the ARF4 gene.[1][2] # Function ADP-ribosylation factor 4 (ARF4) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play ...
https://www.wikidoc.org/index.php/ARF4
641e5c47da016aee74c12c47f459d56b04cc1a59
wikidoc
ARL2
ARL2 ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene. # Function The ADP-ribosylation factor (ARF) genes are small GTP-binding proteins of the RAS superfamily. ARL2 is a member of a functionally distinct group of ARF-like genes. # Interactions ARL2 has been shown to int...
ARL2 ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene.[1][2][3] # Function The ADP-ribosylation factor (ARF) genes are small GTP-binding proteins of the RAS superfamily. ARL2 is a member of a functionally distinct group of ARF-like genes.[3] # Interactions ARL2 has been...
https://www.wikidoc.org/index.php/ARL2
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wikidoc
ART4
ART4 Ecto-ADP-ribosyltransferase 4 is an enzyme that in humans is encoded by the ART4 gene. ART4 has also been designated as CD297 (cluster of differentiation 297). # Function This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enz...
ART4 Ecto-ADP-ribosyltransferase 4 is an enzyme that in humans is encoded by the ART4 gene.[1][2] ART4 has also been designated as CD297 (cluster of differentiation 297). # Function This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family ...
https://www.wikidoc.org/index.php/ART4
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wikidoc
ASK1
ASK1 Apoptosis signal-regulating kinase 1 (ASK1) also known as mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is a member of MAP kinase kinase kinase family and as such a part of mitogen-activated protein kinase pathway. It activates c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinases in ...
ASK1 Apoptosis signal-regulating kinase 1 (ASK1) also known as mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is a member of MAP kinase kinase kinase family and as such a part of mitogen-activated protein kinase pathway. It activates c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinases in...
https://www.wikidoc.org/index.php/ASK1
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wikidoc
ASPH
ASPH Aspartyl/asparaginyl beta-hydroxylase (HAAH) is an enzyme that in humans is encoded by the ASPH gene. ASPH is a alpha-ketoglutarate-dependent hydroxylase, a superfamily non-haem iron-containing proteins. # Function This gene is thought to play an important role in calcium homeostasis. Alternative splicing of this...
ASPH Aspartyl/asparaginyl beta-hydroxylase (HAAH) is an enzyme that in humans is encoded by the ASPH gene.[1][2][3] ASPH is a alpha-ketoglutarate-dependent hydroxylase, a superfamily non-haem iron-containing proteins. # Function This gene is thought to play an important role in calcium homeostasis. Alternative splici...
https://www.wikidoc.org/index.php/ASPH
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wikidoc
ATF1
ATF1 Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression ...
ATF1 Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression...
https://www.wikidoc.org/index.php/ATF1
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wikidoc
ATF3
ATF3 Cyclic AMP-dependent transcription factor ATF-3 is a protein that, in humans, is encoded by the ATF3 gene. # Function Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript v...
ATF3 Cyclic AMP-dependent transcription factor ATF-3 is a protein that, in humans, is encoded by the ATF3 gene.[1] # Function Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcri...
https://www.wikidoc.org/index.php/ATF3
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wikidoc
ATF4
ATF4 Activating transcription factor 4 (tax-responsive enhancer element B67), also known as ATF4, is a protein that in humans is encoded by the ATF4 gene. # Function This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-respon...
ATF4 Activating transcription factor 4 (tax-responsive enhancer element B67), also known as ATF4, is a protein that in humans is encoded by the ATF4 gene.[1][2] # Function This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax...
https://www.wikidoc.org/index.php/ATF4
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wikidoc
ATF5
ATF5 Activating transcription factor 5, also known as ATF5, is a protein that, in humans, is encoded by the ATF5 gene. # Function First described by Nishizawa and Nagata, ATF5 has been classified as a member of the activating transcription factor (ATF)/cAMP response-element binding protein (CREB) family. ATF5 transcri...
ATF5 Activating transcription factor 5, also known as ATF5, is a protein that, in humans, is encoded by the ATF5 gene.[1] # Function First described by Nishizawa and Nagata,[2] ATF5 has been classified as a member of the activating transcription factor (ATF)/cAMP response-element binding protein (CREB) family.[3][4] ...
https://www.wikidoc.org/index.php/ATF5
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wikidoc
ATF7
ATF7 Cyclic AMP-dependent transcription factor ATF-7 is a protein that in humans is encoded by the ATF7 gene. # Homonym In 2001, Peters et al. published a paper showing that ATF-7, a Novel bZIP Protein, interacts with PTP4A1. This ATF-7 is actually ATF5 and not ATF7, as noted by the authors at the end of their paper (...
ATF7 Cyclic AMP-dependent transcription factor ATF-7 is a protein that in humans is encoded by the ATF7 gene.[1][2][3] # Homonym In 2001, Peters et al. published a paper showing that ATF-7, a Novel bZIP Protein, interacts with PTP4A1.[2] This ATF-7 is actually ATF5 and not ATF7, as noted by the authors at the end of ...
https://www.wikidoc.org/index.php/ATF7
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wikidoc
ATG5
ATG5 Autophagy related 5 (ATG5) is a protein that, in humans, is encoded by the ATG5 gene located on Chromosome 6. It is an E3 ubi autophagic cell death. ATG5 is a key protein involved in the extension of the phagophoric membrane in autophagic vesicles. It is activated by ATG7 and forms a complex with ATG12 and ATG16L...
ATG5 Autophagy related 5 (ATG5) is a protein that, in humans, is encoded by the ATG5 gene located on Chromosome 6. It is an E3 ubi autophagic cell death. ATG5 is a key protein involved in the extension of the phagophoric membrane in autophagic vesicles. It is activated by ATG7 and forms a complex with ATG12 and ATG16...
https://www.wikidoc.org/index.php/ATG5
df8a0f67b39b79f88acf64e85ae0a52898eb3bbb
wikidoc
ATG7
ATG7 Autophagy-related protein 7 is a protein in humans encoded by ATG7 gene. Related to GSA7; APG7L; APG7-LIKE. ATG 7, present in both plant and animal genomes, acts as an essential protein for cell degradation and its recycling. The sequence associates with the ubiquitin- proteasome system, UPS, required for the uniq...
ATG7 Autophagy-related protein 7 is a protein in humans encoded by ATG7 gene.[1][2] Related to GSA7; APG7L; APG7-LIKE.[2] ATG 7, present in both plant and animal genomes, acts as an essential protein for cell degradation and its recycling.[3][4] The sequence associates with the ubiquitin- proteasome system, UPS, requi...
https://www.wikidoc.org/index.php/ATG7
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wikidoc
ATRX
ATRX Transcriptional regulator ATRX also known as ATP-dependent helicase ATRX, X-linked helicase II, or X-linked nuclear protein (XNP) is a protein that in humans is encoded by the ATRX gene. # Function Transcriptional regulator ATRX contains an ATPase / helicase domain, and thus it belongs to the SWI/SNF family of c...
ATRX Transcriptional regulator ATRX also known as ATP-dependent helicase ATRX, X-linked helicase II, or X-linked nuclear protein (XNP) is a protein that in humans is encoded by the ATRX gene.[1][2][3] # Function Transcriptional regulator ATRX contains an ATPase / helicase domain, and thus it belongs to the SWI/SNF f...
https://www.wikidoc.org/index.php/ATRX
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wikidoc
Acai
Acai # How Acai Berry Health supplements Can Support Males Reveal Their Rock Strong Ab muscles (Greater Than Eating habits and Physical exercise!) The Acai berry has created into quite the cultural phenomenon. It's tough to go anyplace on the Net without having seeing ads to tell you to obey one rule and burn unsightl...
Acai # How Acai Berry Health supplements Can Support Males Reveal Their Rock Strong Ab muscles (Greater Than Eating habits and Physical exercise!) The Acai berry has created into quite the cultural phenomenon. It's tough to go anyplace on the Net without having seeing ads to tell you to obey one rule and burn unsightl...
https://www.wikidoc.org/index.php/Acai
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wikidoc
Acid
Acid - Acid-base extraction - Acid-base reaction - Acid-base physiology - Acid-base homeostasis - Dissociation constant - Acidity function - Buffer solutions - pH - Proton affinity - Self-ionization of water - Acids: Lewis acids Mineral acids Organic acids Strong acids Superacids Weak acids - Lewis acids - Mineral acid...
Acid - Acid-base extraction - Acid-base reaction - Acid-base physiology - Acid-base homeostasis - Dissociation constant - Acidity function - Buffer solutions - pH - Proton affinity - Self-ionization of water - Acids: Lewis acids Mineral acids Organic acids Strong acids Superacids Weak acids - Lewis acids - Mineral aci...
https://www.wikidoc.org/index.php/Acid
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wikidoc
HSN2
HSN2 Hereditary sensory neuropathy, type II also known as HSN2 is a protein which in humans in encoded by the HSN2. It is a single-exon ORF, and a nervous system-specific exon of the WNK1 gene. HSN2 is as an alternatively spliced exon of WNK1 and this selectively occurs in nervous tissues, resulting in WNK1/HSN2 nervo...
HSN2 Hereditary sensory neuropathy, type II also known as HSN2 is a protein which in humans in encoded by the HSN2.[1][2] It is a single-exon ORF, and a nervous system-specific exon of the WNK1 gene. HSN2 is as an alternatively spliced exon of WNK1 and this selectively occurs in nervous tissues, resulting in WNK1/HSN...
https://www.wikidoc.org/index.php/Acroosteolysis_neurogenic
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wikidoc
Acyl
Acyl # Overview An acyl group (IUPAC name: alkanoyl) is a functional group derived by the removal of one or more hydroxyl group from an oxoacid.. In organic chemistry, the acyl group is usually derived from a carboxylic acid of the form RC O OH. It therefore has the formula RC(=O)-, with a double bond between the carb...
Acyl Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview An acyl group (IUPAC name: alkanoyl) is a functional group derived by the removal of one or more hydroxyl group from an oxoacid.[1]. In organic chemistry, the acyl group is usually derived from a carboxylic acid of the form RC O OH. It therefore has t...
https://www.wikidoc.org/index.php/Acyl
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wikidoc
Agar
Agar # Overview Agar is a gelatinous substance chiefly used as a culture medium for microbiological work. It is an unbranched polysaccharide obtained from the cell walls of some species of red algae or seaweed. It can be used as a laxative, a vegetarian gelatin substitute, a thickener for soups, in jellies, ice cream ...
Agar # Overview Agar is a gelatinous substance chiefly used as a culture medium for microbiological work. It is an unbranched polysaccharide obtained from the cell walls of some species of red algae or seaweed. It can be used as a laxative, a vegetarian gelatin substitute, a thickener for soups, in jellies, ice cream ...
https://www.wikidoc.org/index.php/Agar
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wikidoc
Aloe
Aloe Aloe, also written Aloë, is a genus containing about four hundred species of flowering succulent plants. The genus is native to Africa and is common in South Africa's Cape Province and the mountains of tropical Africa, and neighbouring areas such as Madagascar, the Arabian peninsula and the islands off Africa. The...
Aloe Aloe, also written Aloë, is a genus containing about four hundred species of flowering succulent plants. The genus is native to Africa and is common in South Africa's Cape Province and the mountains of tropical Africa, and neighbouring areas such as Madagascar, the Arabian peninsula and the islands off Africa. Th...
https://www.wikidoc.org/index.php/Aloe
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wikidoc
Alum
Alum Alum, (Template:IPAEng) refers to a specific chemical compound and a class of chemical compounds. The specific compound is the hydrated aluminum potassium sulfate with the formula KAl(SO4)2.12H2O. The class of compounds known as alums have the related stoichiometry, AB(SO4)2.12H2O. # Crystal chemistry of the al...
Alum Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Alum, (Template:IPAEng) refers to a specific chemical compound and a class of chemical compounds. The specific compound is the hydrated aluminum potassium sulfate with the formula KAl(SO4)2.12H2O. The class of compounds known as alums have the related stoichiom...
https://www.wikidoc.org/index.php/Alum
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wikidoc
Anus
Anus # Overview In anatomy, the anus (from Latin ānus "ring (circle), anus") is the external opening of the rectum. Closure is controlled by sphincter muscles. Feces are expelled from the body through the anus during the act of defecation, which is the primary function of the anus. Most animals—from simple worms to el...
Anus Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview In anatomy, the anus (from Latin ānus "ring (circle)[1][2], anus") is the external opening of the rectum. Closure is controlled by sphincter muscles. Feces are expelled from the body through the anus during the act of defecation, which is the primary ...
https://www.wikidoc.org/index.php/Anal
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wikidoc
Bite
Bite # Overview A bite is a wound received from the mouth (and in particular, the teeth) of an animal or person. Most animal bites are from dogs or cats, and the pathogens in the wound are composed by the normal oral flora of the biting animal and human skin flora. Animals may bite in self-defense, in an attempt to pr...
Bite Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2] # Overview A bite is a wound received from the mouth (and in particular, the teeth) of an animal or person. Most animal bites are from dogs or cats, and the pathogens in the wound are composed by the norm...
https://www.wikidoc.org/index.php/Animal_bite
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wikidoc
H2N2
H2N2 H2N2 is a subtype of the species Influenza A virus (sometimes called bird flu virus). H2N2 has mutated into various strains including the Asian Flu strain (now extinct in the wild), H3N2, and various strains found in birds. It is also suspected of causing a human pandemic in 1889. # Asian flu The "Asian Flu" was...
H2N2 Template:Flu Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] H2N2 is a subtype of the species Influenza A virus (sometimes called bird flu virus). H2N2 has mutated into various strains including the Asian Flu strain (now extinct in the wild), H3N2, and various strains found in birds. It is also suspected of c...
https://www.wikidoc.org/index.php/Asian_Flu
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wikidoc
Atom
Atom Used as a slang or street name for heroin and marijuana combination. # Overview An atom is the smallest particle that comprises a chemical element. An atom consists of an electron cloud that surrounds a dense nucleus. This nucleus contains positively charged protons and electrically neutral neutrons, whereas the...
Atom Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Used as a slang or street name for heroin and marijuana combination. # Overview An atom is the smallest particle that comprises a chemical element. An atom consists of an electron cloud that surrounds a dense nucleus. This nucleus contains positively charged pr...
https://www.wikidoc.org/index.php/Atom
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wikidoc
Axon
Axon An axon or nerve fibre, is a long, slender projection -f a nerve cell, or neuron, that conducts electrical impulses away from the neuron's cell body or soma. # Anatomy Axons are in effect the primary transmission lines of the nervous system, and as bundles they help make up nerves. Individual axons are microsco...
Axon Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Template:Neuron map An axon or nerve fibre, is a long, slender projection of a nerve cell, or neuron, that conducts electrical impulses away from the neuron's cell body or soma. # Anatomy Axons are in effect the primary transmission lines of the nervous system...
https://www.wikidoc.org/index.php/Axon
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wikidoc
Neem
Neem (Azadirachta indica) trunk in Kolkata W IMG 6190.jpg|100px|thumb| trunk in , ] 'Neem (Azadirachta indica, Melia azadirachta L., Antelaea azadirachta (L.) Adelb.) is a ), DogonYaro (Margosa, Neeb (), Nimtree, Nimba (Vepu, Vempu, Vepa (), Bevu in language|Kannada], Veppam in (language|Tamil]),arya veppu in malayal...
Neem (Azadirachta indica) trunk in Kolkata W IMG 6190.jpg|100px|thumb| trunk in [http://worldselectshop.com/?id=9361 [http://worldselectshop.com/?id=9361 Bengal], [1]] 'Neem (Azadirachta indica, Melia azadirachta L., Antelaea azadirachta (L.) Adelb.) is a [http://worldselectshop.com/?id=9361 in the mahogany family [...
https://www.wikidoc.org/index.php/Azadirachta_indica
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wikidoc
CD45
CD45 In immunology, the CD45 antigen (CD stands for cluster of differentiation) is a protein which was originally called leukocyte common antigen. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular p...
CD45 In immunology, the CD45 antigen (CD stands for cluster of differentiation) is a protein which was originally called leukocyte common antigen.[1] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellul...
https://www.wikidoc.org/index.php/B220
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wikidoc
BAG1
BAG1 BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene. # Function The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated...
BAG1 BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.[1] # Function The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associ...
https://www.wikidoc.org/index.php/BAG1
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wikidoc
BAG3
BAG3 BAG family molecular chaperone regulator 3 is a protein that in humans is encoded by the BAG3 gene. BAG3 is involved in chaperone-assisted selective autophagy. # Function BAG proteins compete with Hip-1 for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approx...
BAG3 BAG family molecular chaperone regulator 3 is a protein that in humans is encoded by the BAG3 gene. BAG3 is involved in chaperone-assisted selective autophagy.[1][2][3][4][5] # Function BAG proteins compete with Hip-1 for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG protein...
https://www.wikidoc.org/index.php/BAG3
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wikidoc
BAP1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) is a deubiquitinating enzyme that in humans is encoded by the BAP1 gene. BAP1 encodes an 80.4 kDa nuclear-localizing protein with a ubiquitin carboxy-terminal hydrolase (UCH) domain that gives BAP1 its deubiquitinase activity. Recent studies have ...
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) is a deubiquitinating enzyme that in humans is encoded by the BAP1 gene.[1][2] BAP1 encodes an 80.4 kDa nuclear-localizing protein with a ubiquitin carboxy-terminal hydrolase (UCH) domain that gives BAP1 its deubiquitinase activity.[1] Recent stu...
https://www.wikidoc.org/index.php/BAP1
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wikidoc
BBS1
BBS1 Bardet-Biedl syndrome 1 protein is a protein that in humans is encoded by the BBS1 gene. BBS1 is part of the BBSome complex, which required for ciliogenesis. Mutations in this gene have been observed in patients with the major form (type 1) of Bardet-Biedl syndrome. # History As of 2008, research results indica...
BBS1 Bardet-Biedl syndrome 1 protein is a protein that in humans is encoded by the BBS1 gene.[1][2][3] BBS1 is part of the BBSome complex, which required for ciliogenesis. Mutations in this gene have been observed in patients with the major form (type 1) of Bardet-Biedl syndrome. # History As of 2008[update], resea...
https://www.wikidoc.org/index.php/BBS1
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wikidoc
BCL3
BCL3 B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are ...
BCL3 B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene.[1][2] This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, whi...
https://www.wikidoc.org/index.php/BCL3
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wikidoc
BCL6
BCL6 B-cell lymphoma 6 protein is a protein that in humans is encoded by the BCL6 gene. Like BCL2, BCL3, BCL5, BCL7A, BCL9 and BCL10, it has clinical significance in lymphoma. # Function The protein encoded by this gene is an evolutionarily conserved zinc finger transcription factor and contains an N-terminal POZ/BTB ...
BCL6 B-cell lymphoma 6 protein is a protein that in humans is encoded by the BCL6 gene.[1] Like BCL2, BCL3, BCL5, BCL7A, BCL9 and BCL10, it has clinical significance in lymphoma. # Function The protein encoded by this gene is an evolutionarily conserved zinc finger transcription factor and contains an N-terminal POZ/...
https://www.wikidoc.org/index.php/BCL6
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wikidoc
BCL9
BCL9 B-cell CLL/lymphoma 9 protein is a protein that in humans is encoded by the BCL9 gene. # Function BCL9, together with its paralogue gene BCL9L (BCL9 like or BCL9.2), have been extensively studied for their role as transcriptional beta-catenin cofactors, fundamental for the transcription of Wnt target genes. Recen...
BCL9 B-cell CLL/lymphoma 9 protein is a protein that in humans is encoded by the BCL9 gene.[1][2] # Function BCL9, together with its paralogue gene BCL9L (BCL9 like or BCL9.2), have been extensively studied for their role as transcriptional beta-catenin cofactors, fundamental for the transcription of Wnt target genes...
https://www.wikidoc.org/index.php/BCL9
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wikidoc
BIN1
BIN1 Myc box-dependent-interacting protein 1, also known as Bridging Integrator-1 and Amphiphysin-2 is a protein that in humans is encoded by the BIN1 gene. This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tu...
BIN1 Myc box-dependent-interacting protein 1, also known as Bridging Integrator-1 and Amphiphysin-2 is a protein that in humans is encoded by the BIN1 gene.[1][2][3] This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with featur...
https://www.wikidoc.org/index.php/BIN1
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wikidoc
BL22
BL22 BL22, also called CAT-3888 or GCR-3888, is an immunotoxin which attaches to and, upon internalization, kills B cells. It has completed a Phase I clinical (human) trial and is currently in a Phase II clinical trial for the treatment of hairy cell leukemia at a Phase I clinical trial for pediatric acute lymphoblast...
BL22 Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] BL22, also called CAT-3888 or GCR-3888, is an immunotoxin which attaches to and, upon internalization, kills B cells. It has completed a Phase I clinical (human) trial and is currently in a Phase II clinical trial for the treatment of hairy cell leukemia at a Ph...
https://www.wikidoc.org/index.php/BL22
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wikidoc
BMI1
BMI1 Polycomb complex protein BMI-1 also known as polycomb group RING finger protein 4 (PCGF4) or RING finger protein 51 (RNF51) is a protein that in humans is encoded by the BMI1 gene (B cell-specific Moloney murine leukemia virus integration site 1). BMI1 is a polycomb ring finger oncogene. # Function BMI1 (B lymph...
BMI1 Polycomb complex protein BMI-1 also known as polycomb group RING finger protein 4 (PCGF4) or RING finger protein 51 (RNF51) is a protein that in humans is encoded by the BMI1 gene (B cell-specific Moloney murine leukemia virus integration site 1).[1][2] BMI1 is a polycomb ring finger oncogene. # Function BMI1 (...
https://www.wikidoc.org/index.php/BMI1
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wikidoc
BNC1
BNC1 Zinc finger protein basonuclin-1 is a protein that in humans is encoded by the BNC1 gene. The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to...
BNC1 Zinc finger protein basonuclin-1 is a protein that in humans is encoded by the BNC1 gene.[1][2] The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is tho...
https://www.wikidoc.org/index.php/BNC1
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wikidoc
BOLL
BOLL Protein boule-like is a protein that in humans is encoded by the BOLL gene. # Function This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DA...
BOLL Protein boule-like is a protein that in humans is encoded by the BOLL gene.[1][2][3] # Function This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoosper...
https://www.wikidoc.org/index.php/BOLL
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wikidoc
BOP1
BOP1 Ribosome biogenesis protein BOP1 is a protein that in humans is encoded by the BOP1 gene. # Function It is a WD40 repeat-containing nucleolar protein involved in rRNA processing, thereby controlling the cell cycle. It is required for the maturation of the 25S and 5.8S ribosomal RNAs. It may serve as an essential ...
BOP1 Ribosome biogenesis protein BOP1 is a protein that in humans is encoded by the BOP1 gene.[1][2] # Function It is a WD40 repeat-containing nucleolar protein involved in rRNA processing, thereby controlling the cell cycle.[3] It is required for the maturation of the 25S and 5.8S ribosomal RNAs. It may serve as an ...
https://www.wikidoc.org/index.php/BOP1
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wikidoc
BPY2
BPY2 Testis-specific basic protein Y 2 also known as basic charge, Y-linked 2 is a protein that in humans is encoded by the BPY2 gene which resides on the Y chromosome. # Function This gene is located in the nonrecombining portion of the Y chromosome, and expressed specifically in testis. The encoded protein interacts...
BPY2 Testis-specific basic protein Y 2 also known as basic charge, Y-linked 2 is a protein that in humans is encoded by the BPY2 gene which resides on the Y chromosome.[1] # Function This gene is located in the nonrecombining portion of the Y chromosome, and expressed specifically in testis. The encoded protein inter...
https://www.wikidoc.org/index.php/BPY2
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wikidoc
BRAF
BRAF Synonyms and keywords: BRAF1; RAFB1; B-RAF1; NS7; v-raf murine sarcoma viral oncogene homolog B # Overview BRAF is a human gene that codes for the protein B-Raf which is involved in signal transduction relating to cell growth. In 2002, it was shown to be faulty (mutated) in human cancers. Mutations in the BRAF g...
BRAF Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Synonyms and keywords: BRAF1; RAFB1; B-RAF1; NS7; v-raf murine sarcoma viral oncogene homolog B # Overview BRAF is a human gene that codes for the protein B-Raf which is involved in signal transduction relating to cell growth. In 2002, it was shown to be faulty ...
https://www.wikidoc.org/index.php/BRAF
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wikidoc
BRD2
BRD2 Bromodomain-containing protein 2 is a protein that in humans is encoded by the BRD2 gene. BRD2 is part of the Bromodomain and Extra-Terminal motif (BET) protein family that also contains BRD3, BRD4, and BRDT in mammals Early descriptions demonstrated that BRD2 gene product is a mitogen-activated kinase which loca...
BRD2 Bromodomain-containing protein 2 is a protein that in humans is encoded by the BRD2 gene. BRD2 is part of the Bromodomain and Extra-Terminal motif (BET) protein family that also contains BRD3, BRD4, and BRDT in mammals [1][2][3] Early descriptions demonstrated that BRD2 gene product is a mitogen-activated kinase ...
https://www.wikidoc.org/index.php/BRD2
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wikidoc
BRD4
BRD4 Bromodomain-containing protein 4 is a protein that in humans is encoded by the BRD4 gene. BRD4 is a member of the BET (bromodomain and extra terminal domain) family, which also includes BRD2, BRD3, and BRDT. BRD4, similar to other BET family members, contains two bromodomains that recognize acetylated lysine resid...
BRD4 Bromodomain-containing protein 4 is a protein that in humans is encoded by the BRD4 gene.[1][2] BRD4 is a member of the BET (bromodomain and extra terminal domain) family, which also includes BRD2, BRD3, and BRDT.[3] BRD4, similar to other BET family members, contains two bromodomains that recognize acetylated ly...
https://www.wikidoc.org/index.php/BRD4
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wikidoc
BRD8
BRD8 Bromodomain-containing protein 8 is a protein that in humans is encoded by the BRD8 gene. The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and i...
BRD8 Bromodomain-containing protein 8 is a protein that in humans is encoded by the BRD8 gene.[1][2][3] The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodo...
https://www.wikidoc.org/index.php/BRD8
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wikidoc
BRDT
BRDT Bromodomain testis-specific protein is a protein that in humans is encoded by the BRDT gene. It is a member of the Bromodomain and Extra-terminal motif (BET) protein family. BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, seri...
BRDT Bromodomain testis-specific protein is a protein that in humans is encoded by the BRDT gene. It is a member of the Bromodomain and Extra-terminal motif (BET) protein family.[1][2] BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic aci...
https://www.wikidoc.org/index.php/BRDT
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wikidoc
BTG1
BTG1 Protein BTG1 is a protein that in humans is encoded by the BTG1 gene. # Function The BTG1 gene locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. It is a member of a family of antiproliferative genes. BTG1 expression is maximal in ...
BTG1 Protein BTG1 is a protein that in humans is encoded by the BTG1 gene.[1][2] # Function The BTG1 gene locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. It is a member of a family of antiproliferative genes. BTG1 expression is maxi...
https://www.wikidoc.org/index.php/BTG1
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wikidoc
BTG2
BTG2 Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene (B-cell translocation gene 2) and in other mammals by the homologous Btg2 gene. This protein controls cell cycle progression and pro...
BTG2 Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene (B-cell translocation gene 2)[1] and in other mammals by the homologous Btg2 gene.[2][3] This protein controls cell cycle progressi...
https://www.wikidoc.org/index.php/BTG2
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wikidoc
BTLA
BTLA B- and T-lymphocyte attenuator is a protein that in humans is encoded by the BTLA gene. BTLA has also been designated as CD272 (cluster of differentiation 272). # Function BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA i...
BTLA B- and T-lymphocyte attenuator is a protein that in humans is encoded by the BTLA gene.[1][2] BTLA has also been designated as CD272 (cluster of differentiation 272). # Function BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4,...
https://www.wikidoc.org/index.php/BTLA
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wikidoc
BUB1
BUB1 Mitotic checkpoint serine/threonine-protein kinase BUB1 also known as BUB1 (budding uninhibited by benzimidazoles 1) is an enzyme that in humans is encoded by the BUB1 gene. Bub1 is a serine/threonine protein kinase first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound to kinetocho...
BUB1 Mitotic checkpoint serine/threonine-protein kinase BUB1 also known as BUB1 (budding uninhibited by benzimidazoles 1) is an enzyme that in humans is encoded by the BUB1 gene.[1][2] Bub1 is a serine/threonine protein kinase first identified in genetic screens of Saccharomyces cerevisiae.[3] The protein is bound to...
https://www.wikidoc.org/index.php/BUB1
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wikidoc
BUB3
BUB3 Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene. Bub3 is a protein involved with the regulation of the Spindle Assembly Checkpoint (SAC); though BUB3 is non-essential in yeast, it is essential in higher eukaryotes. As one of the checkpoint proteins, Bub3 delays the irreversi...
BUB3 Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene.[1][2] Bub3 is a protein involved with the regulation of the Spindle Assembly Checkpoint (SAC); though BUB3 is non-essential in yeast, it is essential in higher eukaryotes. As one of the checkpoint proteins, Bub3 delays the ir...
https://www.wikidoc.org/index.php/BUB3
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wikidoc
Bael
Bael Bael (Aegle marmelos) is a fruit-bearing tree indigenous to dry forests on hills and plains of central and southern India, Myanmar, Pakistan, Bangladesh, Nepal, Vietnam, Laos and Cambodia. It is cultivated throughout India, as well as in Sri Lanka, northern Malaya, Java and in the Philippines. It is also popularly...
Bael Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Bael (Aegle marmelos) is a fruit-bearing tree indigenous to dry forests on hills and plains of central and southern India, Myanmar, Pakistan, Bangladesh, Nepal, Vietnam, Laos and Cambodia. It is cultivated throughout India, as well as in Sri Lanka, northern Malay...
https://www.wikidoc.org/index.php/Bael
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wikidoc
Basi
Basi Basi is a fermented alcoholic beverage made of sugarcane produced in the Philippines and Guyana. # Philippines Basi is the local beverage of Ilocos in northern Luzon in the Philippines where it has been consumed since before the Spanish conquest. In the Philippines, commercial basi is produced by first crushing ...
Basi Basi is a fermented alcoholic beverage made of sugarcane produced in the Philippines and Guyana. # Philippines Basi is the local beverage of Ilocos in northern Luzon in the Philippines where it has been consumed since before the Spanish conquest. In the Philippines, commercial basi is produced by first crushing...
https://www.wikidoc.org/index.php/Basi
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wikidoc
Bile
Bile # Overview Bile (or gall) is a bitter, yellow or green alkaline fluid secreted by hepatocytes from the liver of most vertebrates. In many species, it is stored in the gallbladder between meals and upon eating is discharged into the duodenum where it excretes waste and aids the process of digestion of lipids. # C...
Bile Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Bile (or gall) is a bitter, yellow or green alkaline fluid secreted by hepatocytes from the liver of most vertebrates. In many species, it is stored in the gallbladder between meals and upon eating is discharged into the duodenum where it excretes was...
https://www.wikidoc.org/index.php/Bile
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wikidoc
Bone
Bone # Overview Bones are rigid organs that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red and white blood cells and store minerals. Because bones come in a variety of shapes and have a complex internal and external structure, the...
Bone Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Bones are rigid organs that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red and white blood cells and store minerals. Because bones come in a variety of shapes and ...
https://www.wikidoc.org/index.php/Bone
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wikidoc
Urea
Urea # Overview Urea is an organic compound with the chemical formula (NH2)2CO. Urea is also known as carbamide, especially in the recommended International Nonproprietary Names (rINN) in use in Europe. For example, the medicinal compound hydroxyurea (old British Approved Name) is now hydroxycarbamide. Other names inc...
Urea Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Template:Chembox new Urea is an organic compound with the chemical formula (NH2)2CO. Urea is also known as carbamide, especially in the recommended International Nonproprietary Names (rINN) in use in Europe. For example, the medicinal compound hydroxy...
https://www.wikidoc.org/index.php/Bosch-Meiser_urea_process
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wikidoc
Boza
Boza Boza is a popular fermented beverage in Albania, Bulgaria, the Republic of Macedonia, Montenegro, Romania, Serbia, and Turkey. It is made from fermented wheat in Turkey and wheat or millet in Bulgaria and Romania. It has a thick consistency and a low alcohol content (usually around 1%), and has a slightly acidic s...
Boza Boza is a popular fermented beverage in Albania, Bulgaria, the Republic of Macedonia, Montenegro, Romania, Serbia, and Turkey. It is made from fermented wheat in Turkey and wheat or millet in Bulgaria and Romania. It has a thick consistency and a low alcohol content (usually around 1%), and has a slightly acidic ...
https://www.wikidoc.org/index.php/Boza
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wikidoc
Bubo
Bubo # Overview A bubo (Greek boubôn, "groin") (plural form= buboes) is a swelling of the lymph nodes, found in an infection such as bubonic plague, gonorrhea, tuberculosis or syphilis. According to historical records they were also characteristic of the pandemic responsible for the Black Death and perhaps other anci...
Bubo Template:Search infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview A bubo (Greek boubôn, "groin") (plural form= buboes) is a swelling of the lymph nodes, found in an infection such as bubonic plague, gonorrhea, tuberculosis or syphilis. According to historical records they were also character...
https://www.wikidoc.org/index.php/Bubo
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wikidoc
Rash
Rash # Overview A rash is a change in skin which affects its color, appearance, or texture. A rash may be localized to one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful. The causes, and therefore treatm...
Rash Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shankar Kumar, M.B.B.S. [2]] # Overview A rash is a change in skin which affects its color, appearance, or texture. A rash may be localized to one part of the body, or affect all the skin. Rashes may cause the skin to change color...
https://www.wikidoc.org/index.php/Bullous_rashes
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wikidoc
C1QA
C1QA Complement C1q subcomponent subunit A is a protein that in humans is encoded by the C1QA gene. This gene encodes a major constituent of the human complement system subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been ass...
C1QA Complement C1q subcomponent subunit A is a protein that in humans is encoded by the C1QA gene.[1] This gene encodes a major constituent of the human complement system subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been...
https://www.wikidoc.org/index.php/C1QA
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wikidoc
CA12
CA12 Carbonic anhydrase 12 is an enzyme that in humans is encoded by the CA12 gene. # Function Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-...
CA12 Carbonic anhydrase 12 is an enzyme that in humans is encoded by the CA12 gene.[1][2] # Function Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification...
https://www.wikidoc.org/index.php/CA12
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wikidoc
CA14
CA14 Carbonic anhydrase 14 is an enzyme that in humans is encoded by the CA14 gene. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balanc...
CA14 Carbonic anhydrase 14 is an enzyme that in humans is encoded by the CA14 gene.[1][2] Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base...
https://www.wikidoc.org/index.php/CA14
a72daf4dd15f94d670137e49e4d1e679d25ada0e
wikidoc
CREB
CREB # Overview CREB (cAMP response element-binding) proteins are transcription factors which bind to certain sequences called cAMP response elements (CRE) in DNA and thereby increase or decrease the transcription of certain genes. CREB is highly related (in structure and function) to CREM (cAMP response element modul...
CREB # Overview CREB (cAMP response element-binding) proteins are transcription factors which bind to certain sequences called cAMP response elements (CRE) in DNA and thereby increase or decrease the transcription of certain genes. CREB is highly related (in structure and function) to CREM (cAMP response element modul...
https://www.wikidoc.org/index.php/CAMP_response_element
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wikidoc
NOD2
NOD2 Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), also known as caspase recruitment domain-containing protein 15 (CARD15) or inflammatory bowel disease protein 1 (IBD1), is a protein that in humans is encoded by the NOD2 gene located on chromosome 16. NOD2 plays an important role in the immune...
NOD2 Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), also known as caspase recruitment domain-containing protein 15 (CARD15) or inflammatory bowel disease protein 1 (IBD1), is a protein that in humans is encoded by the NOD2 gene located on chromosome 16.[1][2] NOD2 plays an important role in the...
https://www.wikidoc.org/index.php/CARD15
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wikidoc
CASK
CASK Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene. This gene is also known by several other names: CMG 2 (CAMGUK protein 2), calcium/calmodulin-dependent serine protein kinase 3 and membrane-associated guanylate kinase 2. # Gene This gene is located on the short arm o...
CASK Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene.[1][2] This gene is also known by several other names: CMG 2 (CAMGUK protein 2), calcium/calmodulin-dependent serine protein kinase 3 and membrane-associated guanylate kinase 2. # Gene This gene is located on the shor...
https://www.wikidoc.org/index.php/CASK
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wikidoc
CBFB
CBFB Core-binding factor subunit beta is a protein that in humans is encoded by the CBFB gene. The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis...
CBFB Core-binding factor subunit beta is a protein that in humans is encoded by the CBFB gene.[1][2] The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hemato...
https://www.wikidoc.org/index.php/CBFB
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wikidoc
CBLC
CBLC Signal transduction protein CBL-C is a protein that in humans is encoded by the CBLC gene. CBL proteins, such as CBLC, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC (MIM 190090) homology-2 (SH2) and SH3 domai...
CBLC Signal transduction protein CBL-C is a protein that in humans is encoded by the CBLC gene.[1][2][3] CBL proteins, such as CBLC, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC (MIM 190090) homology-2 (SH2) and...
https://www.wikidoc.org/index.php/CBLC
b607626a54fae532e88c1527f8f61e9c34c090a9
wikidoc
CBR1
CBR1 Carbonyl reductase 1, also known as CBR1, is an enzyme which in humans is encoded by the CBR1 gene. The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones,...
CBR1 Carbonyl reductase 1, also known as CBR1, is an enzyme which in humans is encoded by the CBR1 gene.[1][2][3] The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as...
https://www.wikidoc.org/index.php/CBR1
e7ae8caa2c5738c0ef9e647a1a24d27cf58ecf68
wikidoc
CBX1
CBX1 Chromobox protein homolog 1 is a protein that in humans is encoded by the CBX1 gene. # Function The protein is localized at heterochromatin sites, where it mediates gene silencing. # Model organisms Model organisms have been used in the study of CBX1 function. A conditional knockout mouse line, called Cbx1tm1a(E...
CBX1 Chromobox protein homolog 1 is a protein that in humans is encoded by the CBX1 gene.[1][2] # Function The protein is localized at heterochromatin sites, where it mediates gene silencing.[2] # Model organisms Model organisms have been used in the study of CBX1 function. A conditional knockout mouse line, called ...
https://www.wikidoc.org/index.php/CBX1
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wikidoc
CBX3
CBX3 Chromobox protein homolog 3 is a protein that is encoded by the CBX3 gene in humans. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B recep...
CBX3 Chromobox protein homolog 3 is a protein that is encoded by the CBX3 gene in humans.[1][2] At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin ...
https://www.wikidoc.org/index.php/CBX3
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wikidoc
CCL2
CCL2 For the ICAO airport code see Candle Lake Airpark, for the diradical compound see Dichlorocarbene. The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family. CCL2 recr...
CCL2 For the ICAO airport code see Candle Lake Airpark, for the diradical compound see Dichlorocarbene. The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family. CCL2 rec...
https://www.wikidoc.org/index.php/CCL2
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wikidoc
CCL3
CCL3 Chemokine (C-C motif) ligand 3 (CCL3) also known as macrophage inflammatory protein 1-alpha (MIP-1-alpha) is a protein that in humans is encoded by the CCL3 gene. # Function CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation o...
CCL3 Chemokine (C-C motif) ligand 3 (CCL3) also known as macrophage inflammatory protein 1-alpha (MIP-1-alpha) is a protein that in humans is encoded by the CCL3 gene.[1] # Function CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activati...
https://www.wikidoc.org/index.php/CCL3
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wikidoc
CCL4
CCL4 Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. # Function CCL4, also known as Macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety ...
CCL4 Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene.[1] # Function CCL4, also known as Macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a vari...
https://www.wikidoc.org/index.php/CCL4
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wikidoc
CCL5
CCL5 Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene. It is also known as RANTES (regulated on activation, normal T cell expressed and secreted). # Function CCL5 is an 8kDa protein classified as a chemotactic cytokine or chemokine. CCL5 is chemotactic for T cells, e...
CCL5 Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene.[1] It is also known as RANTES (regulated on activation, normal T cell expressed and secreted). # Function CCL5 is an 8kDa protein classified as a chemotactic cytokine or chemokine. CCL5 is chemotactic for T cell...
https://www.wikidoc.org/index.php/CCL5
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wikidoc
CCL8
CCL8 Chemokine (C-C motif) ligand 8 (CCL8), also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene. CCL8 is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produc...
CCL8 Chemokine (C-C motif) ligand 8 (CCL8), also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene.[1][2] CCL8 is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to...
https://www.wikidoc.org/index.php/CCL8
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wikidoc
CCM2
CCM2 The CCM2 gene contains 10 coding exons and an alternatively spliced exon 1B. This gene is located on chromosome 7p13 and loss of function mutations on CCM2 lead to the onset of Cerebral Cavernous Malformations (CCM) illness. Cerebral cavernous malformations (CCMs) are vascular malformations in the brain and spi...
CCM2 The CCM2 gene contains 10 coding exons and an alternatively spliced exon 1B. This gene is located on chromosome 7p13 and loss of function mutations on CCM2 lead to the onset of Cerebral Cavernous Malformations (CCM) illness.[1] Cerebral cavernous malformations (CCMs) are vascular malformations in the brain and...
https://www.wikidoc.org/index.php/CCM2