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wikidoc
Soap
Soap Soap is a surfactant used in conjunction with water for washing and cleaning that is available in solid bars and in the form of a viscous liquid. Chemically, soap is a salt of a fatty acid. Traditionally, soap is made by the reaction between a fat and a strong alkali such as lye (sodium hydroxide), potash (potassi...
Soap Soap is a surfactant used in conjunction with water for washing and cleaning that is available in solid bars and in the form of a viscous liquid. Chemically, soap is a salt of a fatty acid. Traditionally, soap is made by the reaction between a fat and a strong alkali such as lye (sodium hydroxide), potash (potass...
https://www.wikidoc.org/index.php/Cold_process
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wikidoc
Cube
Cube A cube is a three-dimensional solid object bounded by six square faces, facets or sides, with three meeting at each vertex. The cube can also be called a regular hexahedron and is one of the five Platonic solids. It is a special kind of square prism, of rectangular parallelepiped and of 3-sided trapezohedron. The ...
Cube Template:Reg polyhedra db A cube[1] is a three-dimensional solid object bounded by six square faces, facets or sides, with three meeting at each vertex. The cube can also be called a regular hexahedron and is one of the five Platonic solids. It is a special kind of square prism, of rectangular parallelepiped and ...
https://www.wikidoc.org/index.php/Cube
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wikidoc
Cure
Cure A cure is a substance or procedure that makes a sick or diseased person well. A cure can be a medication, a surgical operation, a change in lifestyle, or even a philosophical mindset that helps a person heal. # Difference between preventions, treatments, and cures A prevention or preventive measure is a way to av...
Cure A cure is a substance or procedure that makes a sick or diseased person well. A cure can be a medication, a surgical operation, a change in lifestyle, or even a philosophical mindset that helps a person heal. # Difference between preventions, treatments, and cures A prevention or preventive measure is a way to a...
https://www.wikidoc.org/index.php/Cure
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wikidoc
Skin
Skin In zootomy and dermatology, skin is the largest organ of the integumentary system made up of multiple layers of epithelial tissues that guard underlying muscles and organs. Skin pigmentation (see: human skin color or coloring) varies among populations, and skin type can range from dry skin to oily skin. The adject...
Skin Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] In zootomy and dermatology, skin is the largest organ of the integumentary system made up of multiple layers of epithelial tissues that guard underlying muscles and organs. [1] Skin pigmentation (see: human skin color or coloring) varies among populations, and sk...
https://www.wikidoc.org/index.php/Cutaneous
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wikidoc
GJA5
GJA5 Gap junction alpha-5 protein (GJA5), also known as connexin 40 (Cx40) — is a protein that in humans is encoded by the GJA5 gene. # Function This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a ...
GJA5 Gap junction alpha-5 protein (GJA5), also known as connexin 40 (Cx40) — is a protein that in humans is encoded by the GJA5 gene. # Function This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a...
https://www.wikidoc.org/index.php/Cx40
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wikidoc
Cyst
Cyst # Overview A cyst is a closed sac having a distinct membrane and division on the nearby tissue. It may contain air, fluid, or semi-solid material. A collection of pus is called an abscess, not a cyst. Once formed, the cyst will remain in the tissue but can be removed by surgery or resolve by taking medications. A...
Cyst Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2] # Overview A cyst is a closed sac having a distinct membrane and division on the nearby tissue. It may contain air, fluid, or semi-solid material. A collection of pus is called an abscess, not a cyst. Once fo...
https://www.wikidoc.org/index.php/Cyst
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wikidoc
DAB1
DAB1 The Disabled-1 (Dab1) gene encodes a key regulator of Reelin signaling. Reelin is a large glycoprotein secreted by neurons of the developing brain, particularly Cajal-Retzius cells. DAB1 functions downstream of Reln in a signaling pathway that controls cell positioning in the developing brain and during adult neur...
DAB1 The Disabled-1 (Dab1) gene encodes a key regulator of Reelin signaling. Reelin is a large glycoprotein secreted by neurons of the developing brain, particularly Cajal-Retzius cells. DAB1 functions downstream of Reln in a signaling pathway that controls cell positioning in the developing brain and during adult neu...
https://www.wikidoc.org/index.php/DAB1
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wikidoc
DAP3
DAP3 28S ribosomal protein S29, mitochondrial, also known as death-associated protein 3 (DAP3), is a protein that in humans is encoded by the DAP3 gene on chromosome 1. This gene encodes a 28S subunit protein of the mitochondrial ribosome (mitoribosome) and plays key roles in translation, cellular respiration, and apop...
DAP3 28S ribosomal protein S29, mitochondrial, also known as death-associated protein 3 (DAP3), is a protein that in humans is encoded by the DAP3 gene on chromosome 1.[1][2][3][4] This gene encodes a 28S subunit protein of the mitochondrial ribosome (mitoribosome) and plays key roles in translation, cellular respirat...
https://www.wikidoc.org/index.php/DAP3
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wikidoc
DAPI
DAPI DAPI or 4',6-diamidino-2-phenylindole is a fluorescent stain that binds strongly to DNA. It is used extensively in fluorescence microscopy. Since DAPI will pass through an intact cell membrane, it may be used to stain both live and fixed cells. For fluorescence microscopy, DAPI is excited with ultraviolet light....
DAPI Template:Chembox new DAPI or 4',6-diamidino-2-phenylindole is a fluorescent stain that binds strongly to DNA. It is used extensively in fluorescence microscopy. Since DAPI will pass through an intact cell membrane, it may be used to stain both live and fixed cells. For fluorescence microscopy, DAPI is excited w...
https://www.wikidoc.org/index.php/DAPI
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wikidoc
DASB
DASB DASB is a compound that binds to the serotonin transporter. Labeled with carbon-11 — a radioactive isotope — it has been used as a radioligand in neuroimaging with positron emission tomography (PET) since around year 2000. In this context it is regarded as one of the superior radioligands for PET study of the sero...
DASB DASB is a compound that binds to the serotonin transporter. Labeled with carbon-11 — a radioactive isotope — it has been used as a radioligand in neuroimaging with positron emission tomography (PET) since around year 2000.[1] In this context it is regarded as one of the superior radioligands for PET study of the ...
https://www.wikidoc.org/index.php/DASB
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wikidoc
DAX1
DAX1 DAX1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1) is a nuclear receptor protein that in humans is encoded by the NR0B1 gene (nuclear receptor subfamily 0, group B, member 1). The NR0B1 gene is located on the short (p) arm of the X chromosome between positions 21.3 an...
DAX1 DAX1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1) is a nuclear receptor protein that in humans is encoded by the NR0B1 gene (nuclear receptor subfamily 0, group B, member 1).[1][2][3] The NR0B1 gene is located on the short (p) arm of the X chromosome between positio...
https://www.wikidoc.org/index.php/DAX1
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wikidoc
DAZ1
DAZ1 Deleted in azoospermia 1, also known as DAZ1, is a protein which in humans is encoded by the DAZ1 gene. # Function This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to pre-meiotic germ cells, particularly in spermatog...
DAZ1 Deleted in azoospermia 1, also known as DAZ1, is a protein which in humans is encoded by the DAZ1 gene.[1][2] # Function This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to pre-meiotic germ cells, particularly in sp...
https://www.wikidoc.org/index.php/DAZ1
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wikidoc
DBC1
DBC1 Deleted in bladder cancer protein 1 is a protein that in humans is encoded by the DBC1 gene. This gene is located within chromosome 9 (9q32-33), a chromosomal region that frequently shows loss of heterozygosity in transitional cell carcinoma of the bladder. It contains a 5' CpG island that may be a frequent targe...
DBC1 Deleted in bladder cancer protein 1 is a protein that in humans is encoded by the DBC1 gene.[1][2][3][4][5] This gene is located within chromosome 9 (9q32-33), a chromosomal region that frequently shows loss of heterozygosity in transitional cell carcinoma of the bladder. It contains a 5' CpG island that may be ...
https://www.wikidoc.org/index.php/DBC1
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wikidoc
DBN1
DBN1 Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amou...
DBN1 Drebrin is a protein that in humans is encoded by the DBN1 gene.[1][2] The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in t...
https://www.wikidoc.org/index.php/DBN1
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wikidoc
DCC1
DCC1 Sister chromatid cohesion protein DCC1 is a protein that in humans is encoded by the DSCC1 gene. # Model organisms Model organisms have been used in the study of DSCC1 function. A conditional knockout mouse line, called Dscc1tm1a(KOMP)Wtsi was generated at the Wellcome Trust Sanger Institute as part of the Intern...
DCC1 Sister chromatid cohesion protein DCC1 is a protein that in humans is encoded by the DSCC1 gene.[1][2] # Model organisms Model organisms have been used in the study of DSCC1 function. A conditional knockout mouse line, called Dscc1tm1a(KOMP)Wtsi[8][9] was generated at the Wellcome Trust Sanger Institute as part ...
https://www.wikidoc.org/index.php/DCC1
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wikidoc
DDB1
DDB1 DNA damage-binding protein 1 is a protein that in humans is encoded by the DDB1 gene. # Gene The gene's position is on chromosome 11q12-q13. # Protein The DDB1 gene encodes the large subunit of DNA damage-binding protein, a heterodimer composed of a large and a small (DDB2) subunit. DDB1 contains 1140 amino acid...
DDB1 DNA damage-binding protein 1 is a protein that in humans is encoded by the DDB1 gene.[1][2][3] # Gene The gene's position is on chromosome 11q12-q13.[4] # Protein The DDB1 gene encodes the large subunit of DNA damage-binding protein, a heterodimer composed of a large and a small (DDB2) subunit. DDB1 contains 11...
https://www.wikidoc.org/index.php/DDB1
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wikidoc
DDB2
DDB2 DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene. # Structure As indicated by Rapić-Otrin et al. in 2003, the DDB2 gene is located on human chromosome 11p11.2, spans a region of approximately 24 – 26 kb and includes 10 exons. The DDB2 protein contains five putative WD40 repea...
DDB2 DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene.[1][2] # Structure As indicated by Rapić-Otrin et al. in 2003,[3] the DDB2 gene is located on human chromosome 11p11.2, spans a region of approximately 24 – 26 kb and includes 10 exons. The DDB2 protein contains five putative ...
https://www.wikidoc.org/index.php/DDB2
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wikidoc
DEET
DEET N,N-diethyl-m-toluamide, abbreviated DEET, is an insect repellent chemical. It is intended to be applied to the skin or to clothing, and is primarily used to protect against insect bites. In particular, DEET protects against tick bites (which transmit Lyme disease) and mosquito bites (which transmit dengue fever,...
DEET Template:Chembox new N,N-diethyl-m-toluamide, abbreviated DEET, is an insect repellent chemical. It is intended to be applied to the skin or to clothing, and is primarily used to protect against insect bites. In particular, DEET protects against tick bites (which transmit Lyme disease) and mosquito bites (which ...
https://www.wikidoc.org/index.php/DEET
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wikidoc
DFFA
DFFA DNA fragmentation factor subunit alpha (DFFA), also known as Inhibitor of caspase-activated DNase (ICAD), is a protein that in humans is encoded by the DFFA gene. Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkag...
DFFA DNA fragmentation factor subunit alpha (DFFA), also known as Inhibitor of caspase-activated DNase (ICAD), is a protein that in humans is encoded by the DFFA gene.[1][2][3] Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied b...
https://www.wikidoc.org/index.php/DFFA
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wikidoc
DKK1
DKK1 Dickkopf-related protein 1 is a protein that in humans is encoded by the DKK1 gene. # Function This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the Wnt signaling pathway. ...
DKK1 Dickkopf-related protein 1 is a protein that in humans is encoded by the DKK1 gene.[1] # Function This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the Wnt signaling pathw...
https://www.wikidoc.org/index.php/DKK1
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wikidoc
DLC1
DLC1 Deleted in Liver Cancer 1 also known as DLC1 and StAR-related lipid transfer protein 12 (STARD12) is a protein which in humans is encoded by the DLC1 gene. This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that...
DLC1 Deleted in Liver Cancer 1 also known as DLC1 and StAR-related lipid transfer protein 12 (STARD12) is a protein which in humans is encoded by the DLC1 gene.[1][2] This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggest...
https://www.wikidoc.org/index.php/DLC1
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wikidoc
DLCO
DLCO # Overview DLCO stands for the Diffusing capacity of the Lung for Carbon Monoxide, the test used to determine this parameter. DLCO is the extent to which oxygen passes from the air sacs of the lungs into the blood. It was introduced in 1909. # Mechanism of test The DLCO Test This test involves measuring the part...
DLCO Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview DLCO stands for the Diffusing capacity of the Lung for Carbon Monoxide, the test used to determine this parameter. DLCO is the extent to which oxygen passes from the air sacs of the lungs into the blood. It was introduced in 1909.[1] # Mechanism of t...
https://www.wikidoc.org/index.php/DLCO
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wikidoc
DLG1
DLG1 Discs large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a scaffold protein that in humans is encoded by the SAP97 gene. SAP97 is a mammalian MAGUK-family member protein that is similar to the Drosophila protein Dlg1 (the protein is alternatively referred to as hDlg1, and the human ge...
DLG1 Discs large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a scaffold protein that in humans is encoded by the SAP97 gene. SAP97 is a mammalian MAGUK-family member protein that is similar to the Drosophila protein Dlg1 (the protein is alternatively referred to as hDlg1, and the human g...
https://www.wikidoc.org/index.php/DLG1
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wikidoc
DLG2
DLG2 Disks large homolog 2 (DLG2) also known as channel-associated protein of synapse-110 (chapsyn-110) or postsynaptic density protein 93 (PSD-93) is a protein that in humans is encoded by the DLG2 gene. # Function Chapsyn-110/PSD-93 a member of the membrane-associated guanylate kinase (MAGUK) family. The protein for...
DLG2 Disks large homolog 2 (DLG2) also known as channel-associated protein of synapse-110 (chapsyn-110) or postsynaptic density protein 93 (PSD-93) is a protein that in humans is encoded by the DLG2 gene.[1][2] # Function Chapsyn-110/PSD-93 a member of the membrane-associated guanylate kinase (MAGUK) family. The prot...
https://www.wikidoc.org/index.php/DLG2
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wikidoc
DLG4
DLG4 PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (discs large homolog 4) gene. PSD-95 is a member of the membrane-associated guanylate kinase (MAGUK) family. With PSD-93 it is recruited into the same NMDA receptor and p...
DLG4 PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (discs large homolog 4) gene.[1][2][3] PSD-95 is a member of the membrane-associated guanylate kinase (MAGUK) family. With PSD-93 it is recruited into the same NMDA rece...
https://www.wikidoc.org/index.php/DLG4
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wikidoc
DLK1
DLK1 Protein delta homolog 1 is a protein that in humans is encoded by the DLK1 gene. It is expressed as a transmembrane protein, but a soluble form cleaved off by ADAM17 is active in inhibiting adipogenesis, the differentiation of pre-adipocytes into adipocytes. It is a member of the EGF-like family of homeotic protei...
DLK1 Protein delta homolog 1 is a protein that in humans is encoded by the DLK1 gene.[1][2][3] It is expressed as a transmembrane protein, but a soluble form cleaved off by ADAM17 is active in inhibiting adipogenesis,[4] the differentiation of pre-adipocytes into adipocytes.[5] It is a member of the EGF-like family of...
https://www.wikidoc.org/index.php/DLK1
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wikidoc
DLL3
DLL3 Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene. Two transcript variants encoding distinct isoforms have been identified for this gene. # Function This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are ...
DLL3 Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene.[1] Two transcript variants encoding distinct isoforms have been identified for this gene. # Function This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that ...
https://www.wikidoc.org/index.php/DLL3
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wikidoc
DLST
DLST Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial is an enzyme that in humans is encoded by the DLST gene. # Interactive pathway map Click on genes, proteins and metabolites below to link to respective articles. - ↑ The interactive pathway map can be...
DLST Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial is an enzyme that in humans is encoded by the DLST gene.[1][2] # Interactive pathway map Click on genes, proteins and metabolites below to link to respective articles. [§ 1] - ↑ The interactive pathwa...
https://www.wikidoc.org/index.php/DLST
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wikidoc
DLX2
DLX2 Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene. Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dl...
DLX2 Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene.[1][2] Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-l...
https://www.wikidoc.org/index.php/DLX2
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wikidoc
DLX3
DLX3 Homeobox protein DLX-3 is a protein that in humans is encoded by the DLX3 gene. # Function Dlx3 is a crucial regulator of hair follicle differentiation and cycling. Specifically, colocalization of phosphorylated Smad1 / 5 / 8 complex and Dlx3 regulate role for BMP signaling to Dlx3 during hair morphogenesis in an...
DLX3 Homeobox protein DLX-3 is a protein that in humans is encoded by the DLX3 gene.[1][2] # Function Dlx3 is a crucial regulator of hair follicle differentiation and cycling. Specifically, colocalization of phosphorylated Smad1 / 5 / 8 complex and Dlx3 regulate role for BMP signaling to Dlx3 during hair morphogenesi...
https://www.wikidoc.org/index.php/DLX3
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wikidoc
DLX5
DLX5 Homeobox protein DLX-5 is a protein that in humans is encoded by the distal-less homeobox 5 gene, or DLX5 gene. DLX5 is a member of DLX gene family. # Function This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less (Dll) gene. The encoded protein may play a...
DLX5 Homeobox protein DLX-5 is a protein that in humans is encoded by the distal-less homeobox 5 gene, or DLX5 gene.[1][2] DLX5 is a member of DLX gene family. # Function This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less (Dll) gene. The encoded protein may...
https://www.wikidoc.org/index.php/DLX5
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wikidoc
DMT1
DMT1 The divalent metal transporter 1 (DMT1), also known as natural resistance-associated macrophage protein 2 (NRAMP 2), and divalent cation transporter 1 (DCT1), is a protein that in humans is encoded by the SLC11A2 (solute carrier family 11, member 2) gene. DMT1 represents a large family of orthologous metal ion tra...
DMT1 The divalent metal transporter 1 (DMT1), also known as natural resistance-associated macrophage protein 2 (NRAMP 2), and divalent cation transporter 1 (DCT1),[1] is a protein that in humans is encoded by the SLC11A2 (solute carrier family 11, member 2) gene.[2] DMT1 represents a large family of orthologous metal ...
https://www.wikidoc.org/index.php/DMT-1
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wikidoc
DNM2
DNM2 Dynamin-2 is a protein that in humans is encoded by the DNM2 gene. # Function Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtu...
DNM2 Dynamin-2 is a protein that in humans is encoded by the DNM2 gene.[1][2] # Function Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with ...
https://www.wikidoc.org/index.php/DNM2
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wikidoc
DOK2
DOK2 Docking protein 2 is a protein that in humans is encoded by the DOK2 gene. # Function The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/...
DOK2 Docking protein 2 is a protein that in humans is encoded by the DOK2 gene.[1][2][3] # Function The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for...
https://www.wikidoc.org/index.php/DOK2
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wikidoc
DPM1
DPM1 Dolichol-phosphate mannosyltransferase is an enzyme that in humans is encoded by the DPM1 gene. # Function Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored...
DPM1 Dolichol-phosphate mannosyltransferase is an enzyme that in humans is encoded by the DPM1 gene.[1][2][3] # Function Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GP...
https://www.wikidoc.org/index.php/DPM1
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wikidoc
DPM2
DPM2 Dolichol phosphate-mannose biosynthesis regulatory protein is a protein that in humans is encoded by the DPM2 gene. # Function Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface express...
DPM2 Dolichol phosphate-mannose biosynthesis regulatory protein is a protein that in humans is encoded by the DPM2 gene.[1] # Function Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface exp...
https://www.wikidoc.org/index.php/DPM2
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wikidoc
DPM3
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3, also known as DPM3, is a human gene. # Function Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored prote...
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3, also known as DPM3, is a human gene.[1][2] # Function Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchore...
https://www.wikidoc.org/index.php/DPM3
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wikidoc
DPYD
DPYD Dihydropyrimidine dehydrogenase is an enzyme that in humans is encoded by the DPYD gene. # Function The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Genetic deficiency of this enzyme results in an error i...
DPYD Dihydropyrimidine dehydrogenase [NADP+] is an enzyme that in humans is encoded by the DPYD gene.[1][2] # Function The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Genetic deficiency of this enzyme results...
https://www.wikidoc.org/index.php/DPYD
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wikidoc
DPYS
DPYS Dihydropyrimidinase is an enzyme that in humans is encoded by the DPYS gene. Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transc...
DPYS Dihydropyrimidinase is an enzyme that in humans is encoded by the DPYS gene.[1][2] Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb...
https://www.wikidoc.org/index.php/DPYS
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wikidoc
DSC2
DSC2 Desmocollin-2 is a protein that in humans is encoded by the DSC2 gene. Desmocollin-2 is a cadherin-type protein that functions to link adjacent cells together in specialized regions known as desmosomes. Desmocollin-2 is widely expressed, and is the only desmocollin isoform expressed in cardiac muscle, where it loc...
DSC2 Desmocollin-2 is a protein that in humans is encoded by the DSC2 gene.[1][2] Desmocollin-2 is a cadherin-type protein that functions to link adjacent cells together in specialized regions known as desmosomes. Desmocollin-2 is widely expressed, and is the only desmocollin isoform expressed in cardiac muscle, where...
https://www.wikidoc.org/index.php/DSC2
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wikidoc
DSC3
DSC3 Desmocollin-3 is a protein that in humans is encoded by the DSC3 gene. # Gene The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms. # Function Desmocollin-3 is a calcium...
DSC3 Desmocollin-3 is a protein that in humans is encoded by the DSC3 gene.[1][2][3] # Gene The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.[3] # Function Desmocollin-3...
https://www.wikidoc.org/index.php/DSC3
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wikidoc
DTNA
DTNA Dystrobrevin alpha is a protein that in humans is encoded by the DTNA gene. # Function The protein encoded by this gene belongs to the dystrobrevin subfamily and the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integr...
DTNA Dystrobrevin alpha is a protein that in humans is encoded by the DTNA gene.[1][2][3] # Function The protein encoded by this gene belongs to the dystrobrevin subfamily and the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and seve...
https://www.wikidoc.org/index.php/DTNA
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wikidoc
DUID
DUID DUID is the acronym that stands for Driving Under the Influence of Drugs. It is akin to DUI or DWI for driving under the influence of alcohol or driving while intoxicated. Several American states and European countries now have "per se" DUID laws that presume a driver is impaired if they are found to have any dete...
DUID Template:Globalize DUID is the acronym that stands for Driving Under the Influence of Drugs. It is akin to DUI or DWI for driving under the influence of alcohol or driving while intoxicated. Several American states and European countries now have "per se" DUID laws that presume a driver is impaired if they are fo...
https://www.wikidoc.org/index.php/DUID
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wikidoc
DUX4
DUX4 Double homeobox, 4 also known as DUX4 is a protein which in humans is encoded by the DUX4 gene. # Gene This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q35. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z...
DUX4 Double homeobox, 4 also known as DUX4 is a protein which in humans is encoded by the DUX4 gene.[1] # Gene This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q35. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each...
https://www.wikidoc.org/index.php/DUX4
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wikidoc
DVL2
DVL2 Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein th...
DVL2 Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene.[1][2] This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD pro...
https://www.wikidoc.org/index.php/DVL2
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wikidoc
DVL3
DVL3 Segment polarity protein dishevelled homolog DVL-3 is a protein that in humans is encoded by the DVL3 gene. This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell...
DVL3 Segment polarity protein dishevelled homolog DVL-3 is a protein that in humans is encoded by the DVL3 gene.[1][2] This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulat...
https://www.wikidoc.org/index.php/DVL3
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wikidoc
Data
Data Data in everyday language is a synonym for information. In the exact sciences there is a clear distinction between data and information, where data is a measurement that can be disorganized and when the data becomes organized it becomes information. Data may relate to reality, or to fiction as in a fictional movi...
Data Data in everyday language is a synonym for information.[1] In the exact sciences there is a clear distinction between data and information, where data is a measurement that can be disorganized and when the data becomes organized it becomes information. Data may relate to reality, or to fiction as in a fictional ...
https://www.wikidoc.org/index.php/Data
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wikidoc
Zinc
Zinc # Overview Zinc (Template:PronEng) is a metallic chemical element with the symbol Zn and atomic number 30. In some historical and sculptural contexts, it is (or was) known as spelter. # Notable characteristics Zinc is a moderately reactive, blue gray metal that tarnishes in moist air and burns in air with a brig...
Zinc Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Template:Infobox zinc # Overview Zinc (Template:PronEng) is a metallic chemical element with the symbol Zn and atomic number 30. In some historical and sculptural contexts, it is (or was) known as spelter. # Notable characteristics Zinc is a moderately reactive...
https://www.wikidoc.org/index.php/Ddx:Zinc
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wikidoc
FOSB
FOSB FBJ murine osteosarcoma viral oncogene homolog B, also known as Finkel-Biskis-Jinkins murine osteosarcoma viral oncogene homolog B, FOSB or FosB, is a protein that, in humans, is encoded by the FOSB gene. The FOS gene family consists of four members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper p...
FOSB FBJ murine osteosarcoma viral oncogene homolog B, also known as Finkel-Biskis-Jinkins murine osteosarcoma viral oncogene homolog B, FOSB or FosB, is a protein that, in humans, is encoded by the FOSB gene.[1][2][3] The FOS gene family consists of four members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucin...
https://www.wikidoc.org/index.php/Delta_FosB
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wikidoc
Diff
Diff A diff is the difference otherwise known as a diff between two versions of a page. It can be viewed from the page history: for every version there are potentially two radio buttons: the left column is for selecting the older version, the right column for selecting the newer one. Pressing "Compare selected versions...
Diff A diff is the difference otherwise known as a diff between two versions of a page. It can be viewed from the page history: for every version there are potentially two radio buttons: the left column is for selecting the older version, the right column for selecting the newer one. Pressing "Compare selected version...
https://www.wikidoc.org/index.php/Diff
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wikidoc
Dill
Dill Dill (Anethum graveolens) is a short-lived annual herb, native to southwest and central Asia. It is the sole species of the genus Anethum, though classified by some botanists in the related genus Peucedanum as Peucedanum graveolens (L.) C.B.Clarke. It grows to 40-60 cm tall, with slender stems and alternate, finel...
Dill Dill (Anethum graveolens) is a short-lived annual herb, native to southwest and central Asia. It is the sole species of the genus Anethum, though classified by some botanists in the related genus Peucedanum as Peucedanum graveolens (L.) C.B.Clarke. It grows to 40-60 cm tall, with slender stems and alternate, fine...
https://www.wikidoc.org/index.php/Dill
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wikidoc
Diol
Diol # Overview A diol or glycol is a chemical compound containing two hydroxyl groups (-OH groups). Vicinal diols have hydroxyl groups attached to adjacent atoms. Examples of vicinal diol compounds are ethylene glycol and propylene glycol. Geminal diols have hydroxyl groups bonded to the same atom. In general, or...
Diol # Overview A diol or glycol is a chemical compound containing two hydroxyl groups (-OH groups). Vicinal diols have hydroxyl groups attached to adjacent atoms. Examples of vicinal diol compounds are ethylene glycol and propylene glycol. Geminal diols have hydroxyl groups bonded to the same atom. In general, or...
https://www.wikidoc.org/index.php/Diol
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wikidoc
Twin
Twin Twins are a form of multiple birth in which the mother gives birth to two offspring from the same pregnancy, either of the same or opposite sex. The general term for more than one offspring from the same pregnancy is multiples, for example triplets refers to cases of three offspring from the same pregnancy. A fet...
Twin Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3] Twins are a form of multiple birth in which the mother gives birth to two offspring from the same pregnancy, either of the same or opposite sex. The general term for more than one offspring from the same pregnancy is multiples, for example triplets refers to case...
https://www.wikidoc.org/index.php/Dizygotic_twins
d6d0e50f7ec79b7ca791a8eac976ea6137bc57a5
wikidoc
Dust
Dust Dust is a general name for minute solid particles with diameters less than 500 micrometers. On Earth, dust occurs in the atmosphere from various sources; soil dust lifted up by wind, volcanic eruptions, and pollution are some examples. Airborne dust is considered an aerosol and can have a strong local radiative fo...
Dust Template:Wiktionarypar Dust is a general name for minute solid particles with diameters less than 500 micrometers. On Earth, dust occurs in the atmosphere from various sources; soil dust lifted up by wind, volcanic eruptions, and pollution are some examples. Airborne dust is considered an aerosol and can have a s...
https://www.wikidoc.org/index.php/Dust
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wikidoc
E2F1
E2F1 Transcription factor E2F1 is a protein that in humans is encoded by the E2F1 gene. # Function The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of th...
E2F1 Transcription factor E2F1 is a protein that in humans is encoded by the E2F1 gene.[1] # Function The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target o...
https://www.wikidoc.org/index.php/E2F1
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wikidoc
E2F4
E2F4 Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene. # Function Gene ID: 1874 E2F transcription factor 4, "The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor sup...
E2F4 Associate Editor(s)-in-Chief: Henry A. Hoff Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene.[1][2] # Function Gene ID: 1874 E2F transcription factor 4, "The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role ...
https://www.wikidoc.org/index.php/E2F4
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wikidoc
EBF1
EBF1 Transcription factor COE1 is a protein that in humans is encoded by the EBF1 gene. EBF1 stands for Early B-Cell Factor 1. EBF1 controls the expression of key proteins required for B cell differentiation, signal transduction and function. The crucial role of this factor is shown in the regulation of expression of ...
EBF1 Transcription factor COE1 is a protein that in humans is encoded by the EBF1 gene. EBF1 stands for Early B-Cell Factor 1.[1][2][3] EBF1 controls the expression of key proteins required for B cell differentiation, signal transduction and function.[4][5] The crucial role of this factor is shown in the regulation o...
https://www.wikidoc.org/index.php/EBF1
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wikidoc
EBI3
EBI3 Epstein-Barr virus induced gene 3, also known as interleukin-27 subunit beta or IL-27B, is a protein which in humans is encoded by the EBI3 gene. # Function This gene was identified by the induction of its expression in B lymphocytes by Epstein-Barr virus infection. The protein encoded by this gene is a secreted ...
EBI3 Epstein-Barr virus induced gene 3, also known as interleukin-27 subunit beta or IL-27B, is a protein which in humans is encoded by the EBI3 gene.[1][2] # Function This gene was identified by the induction of its expression in B lymphocytes by Epstein-Barr virus infection. The protein encoded by this gene is a se...
https://www.wikidoc.org/index.php/EBI3
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wikidoc
EEA1
EEA1 The gene EEA1 encodes for the 1400 amino acid protein, Early Endosome Antigen 1. EEA1 localizes exclusively to early endosomes and has an important role in endosomal trafficking. EEA1 binds directly to the phospholipid phosphatidylinositol 3-phosphate through its C-terminal FYVE domain and forms a homodimer throug...
EEA1 The gene EEA1 encodes for the 1400 amino acid protein, Early Endosome Antigen 1. EEA1 localizes exclusively to early endosomes and has an important role in endosomal trafficking. EEA1 binds directly to the phospholipid phosphatidylinositol 3-phosphate through its C-terminal FYVE domain and forms a homodimer throu...
https://www.wikidoc.org/index.php/EEA1
d479584d908353f7e7bebce22faf6a38f0ef0a25
wikidoc
EEF2
EEF2 Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the ribosome. This protein is complet...
EEF2 Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene.[1][2][3] This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the ribosome. This protein ...
https://www.wikidoc.org/index.php/EEF2
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wikidoc
EGR1
EGR1 EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. EGR-1 is a mammalian transcription factor. It was also named Krox-24, TIS8, and ZENK. It was originally discovered in mic...
EGR1 EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. EGR-1 is a mammalian transcription factor. It was also named Krox-24, TIS8, and ZENK. It was originally discovered in mi...
https://www.wikidoc.org/index.php/EGR1
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wikidoc
EGR2
EGR2 Early growth response protein 2 is a protein that in humans is encoded by the EGR2 gene. EGR2 (also termed Krox20) is a transcription regulatory factor, containing two zinc finger DNA-binding sites, and is highly expressed in a population of migrating neural crest cells. It is later expressed in the neural crest ...
EGR2 Early growth response protein 2 is a protein that in humans is encoded by the EGR2 gene. EGR2 (also termed Krox20) is a transcription regulatory factor, containing two zinc finger DNA-binding sites, and is highly expressed in a population of migrating neural crest cells.[1][2][3] It is later expressed in the neu...
https://www.wikidoc.org/index.php/EGR2
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wikidoc
EHD1
EHD1 EH domain-containing protein 1, also known as testilin or PAST homolog 1 (PAST1), is a protein that in humans is encoded by the EHD1 gene belonging to the EHD protein family. # Function This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding...
EHD1 EH domain-containing protein 1, also known as testilin or PAST homolog 1 (PAST1), is a protein that in humans is encoded by the EHD1 gene[1] belonging to the EHD protein family. # Function This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-bin...
https://www.wikidoc.org/index.php/EHD1
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wikidoc
EID2
EID2 EP300 interacting inhibitor of differentiation 2, also known as EID2 is a human gene. # Function The protein encoded by this gene may function as an endogenous suppressor of TGF-beta signaling and inhibits differentiation by blocking the histone acetyltransferase activity of p300, class I histone deacetylase, HD...
EID2 EP300 interacting inhibitor of differentiation 2, also known as EID2 is a human gene.[1] # Function The protein encoded by this gene may function as an endogenous suppressor of TGF-beta signaling and inhibits differentiation by blocking the histone acetyltransferase activity of p300, class I histone deacetylase...
https://www.wikidoc.org/index.php/EID2
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wikidoc
EIF1
EIF1 Eukaryotic translation initiation factor 1 (eIF1) is a protein that in humans is encoded by the EIF1 gene. eIF1 interacts with the eukaryotic small (40S) ribosomal subunit and eIF3, and is a component of the 43S preinitiation complex (PIC). eIF1 and eIF1A bind cooperatively to the 40S to stabilize an "open" confor...
EIF1 Eukaryotic translation initiation factor 1 (eIF1) is a protein that in humans is encoded by the EIF1 gene.[1][2][3] eIF1 interacts with the eukaryotic small (40S) ribosomal subunit and eIF3, and is a component of the 43S preinitiation complex (PIC).[4] eIF1 and eIF1A bind cooperatively to the 40S to stabilize an ...
https://www.wikidoc.org/index.php/EIF1
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wikidoc
EIF6
EIF6 Eukaryotic translation initiation factor 6 (EIF6), also known as Integrin beta 4 binding protein (ITGB4BP), is a human gene. Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4...
EIF6 Eukaryotic translation initiation factor 6 (EIF6), also known as Integrin beta 4 binding protein (ITGB4BP), is a human gene.[1] Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (I...
https://www.wikidoc.org/index.php/EIF6
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wikidoc
ELK1
ELK1 ETS domain-containing protein Elk-1 is a protein that in humans is encoded by the ELK1 gene. Elk-1 functions as a transcription activator. It is classified as a ternary complex factor (TCF), a subclass of the ETS family, which is characterized by a common protein domain that regulates DNA binding to target sequenc...
ELK1 ETS domain-containing protein Elk-1 is a protein that in humans is encoded by the ELK1 gene. Elk-1 functions as a transcription activator. It is classified as a ternary complex factor (TCF), a subclass of the ETS family, which is characterized by a common protein domain that regulates DNA binding to target sequen...
https://www.wikidoc.org/index.php/ELK1
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wikidoc
ELP4
ELP4 Elongation protein 4 homolog (S. cerevisiae), also known as ELP4, is a protein which in humans is encoded by the ELP4 gene. # Function This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elon...
ELP4 Elongation protein 4 homolog (S. cerevisiae), also known as ELP4, is a protein which in humans is encoded by the ELP4 gene.[1][2][3] # Function This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcript...
https://www.wikidoc.org/index.php/ELP4
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wikidoc
ELSI
ELSI # Overview ELSI stands for Ethical, Legal and Social Issues. It's a term associated with the Human genome project. This project didn't only have the goal to identify all the approximately 24.000 genes in the human DNA, but also to address the ELSI that might arise from the project. 5% of the US annual Human genom...
ELSI # Overview ELSI stands for Ethical, Legal and Social Issues. It's a term associated with the Human genome project. This project didn't only have the goal to identify all the approximately 24.000 genes in the human DNA, but also to address the ELSI that might arise from the project. 5% of the US annual Human genom...
https://www.wikidoc.org/index.php/ELSI
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wikidoc
EMP3
EMP3 Epithelial membrane protein 3 (EMP3) is a trans-membrane signaling molecule that is encoded by the myelin-related gene EMP3. EMP3 is a member of the peripheral myelin protein gene family 22-kDa (PMP22), which is mainly responsible for the formation of the sheath of compact myelin. Although the detailed functions a...
EMP3 Epithelial membrane protein 3 (EMP3) is a trans-membrane signaling molecule that is encoded by the myelin-related gene EMP3. EMP3 is a member of the peripheral myelin protein gene family 22-kDa (PMP22), which is mainly responsible for the formation of the sheath of compact myelin.[1][2] Although the detailed func...
https://www.wikidoc.org/index.php/EMP3
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wikidoc
EMR1
EMR1 EGF-like module-containing mucin-like hormone receptor-like 1 also known as F4/80 is a protein encoded by the ADGRE1 gene. EMR1 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region vi...
EMR1 EGF-like module-containing mucin-like hormone receptor-like 1 also known as F4/80 is a protein encoded by the ADGRE1 gene.[1][2][3][4][5] EMR1 is a member of the adhesion GPCR family.[6][7] Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is lin...
https://www.wikidoc.org/index.php/EMR1
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wikidoc
EMR2
EMR2 EGF-like module-containing mucin-like hormone receptor-like 2 also known as CD312 (cluster of differentiation 312) is a protein encoded by the ADGRE2 gene. EMR2 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules...
EMR2 EGF-like module-containing mucin-like hormone receptor-like 2 also known as CD312 (cluster of differentiation 312) is a protein encoded by the ADGRE2 gene.[1] EMR2 is a member of the adhesion GPCR family.[2][3] Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal prote...
https://www.wikidoc.org/index.php/EMR2
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wikidoc
EMR3
EMR3 EGF-like module-containing mucin-like hormone receptor-like 3 is a protein encoded by the ADGRE3 gene. EMR3 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as ...
EMR3 EGF-like module-containing mucin-like hormone receptor-like 3 is a protein encoded by the ADGRE3 gene.[1][2] EMR3 is a member of the adhesion GPCR family.[3][4] Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a dom...
https://www.wikidoc.org/index.php/EMR3
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wikidoc
EMSY
EMSY EMSY is a protein that in humans is encoded by the EMSY gene. # Clinical significance EMSY has been shown to associate with atopy and susceptibility to poly-sensitisation. # Interactions EMSY has been shown to interact with ZMYND11, BRCA2 and CBX1.
EMSY EMSY is a protein that in humans is encoded by the EMSY gene.[1] # Clinical significance EMSY has been shown to associate with atopy and susceptibility to poly-sensitisation.[2] # Interactions EMSY has been shown to interact with ZMYND11,[3] BRCA2[3] and CBX1.[3]
https://www.wikidoc.org/index.php/EMSY
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wikidoc
EMX1
EMX1 Homeobox protein EMX1 is a protein that in humans is encoded by the EMX1 gene. The transcribed EMX1 gene is a member of the EMX family of transcription factors. The EMX1 gene, along with its family members, are expressed in the developing cerebrum (also known as the telencephalon). Emx1 plays a role in specificati...
EMX1 Homeobox protein EMX1 is a protein that in humans is encoded by the EMX1 gene.[1][2] The transcribed EMX1 gene is a member of the EMX family of transcription factors. The EMX1 gene, along with its family members, are expressed in the developing cerebrum (also known as the telencephalon).[3] Emx1 plays a role in s...
https://www.wikidoc.org/index.php/EMX1
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wikidoc
EMX2
EMX2 Homeobox protein Emx2 is a protein that in humans is encoded by the EMX2 gene. # Function The homeodomain transcription factor EMX2 is critical for central nervous system and urogenital development. EMX1 (MIM 600034) and EMX2 are related to the 'empty spiracles' gene expressed in the developing Drosophila head.. ...
EMX2 Homeobox protein Emx2 is a protein that in humans is encoded by the EMX2 gene.[1][2] # Function The homeodomain transcription factor EMX2 is critical for central nervous system and urogenital development. EMX1 (MIM 600034) and EMX2 are related to the 'empty spiracles' gene expressed in the developing Drosophila ...
https://www.wikidoc.org/index.php/EMX2
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wikidoc
ENAM
ENAM Enamelin is a protein that in humans is encoded by the ENAM gene. Dental enamel is a highly mineralized tissue with 85% of its volume occupied by unusually large, highly organized, hydroxyapatite crystals. This highly organized and unusual structure is thought to be rigorously controlled in ameloblasts through the...
ENAM Enamelin is a protein that in humans is encoded by the ENAM gene.[1][2] Dental enamel is a highly mineralized tissue with 85% of its volume occupied by unusually large, highly organized, hydroxyapatite crystals. This highly organized and unusual structure is thought to be rigorously controlled in ameloblasts thro...
https://www.wikidoc.org/index.php/ENAM
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wikidoc
ENC1
ENC1 Ectoderm-neural cortex protein 1 is a protein that in humans is encoded by the ENC1 gene. # Function DNA damage and/or hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53; MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. Po...
ENC1 Ectoderm-neural cortex protein 1 is a protein that in humans is encoded by the ENC1 gene.[1][2][3] # Function DNA damage and/or hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53; MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all ...
https://www.wikidoc.org/index.php/ENC1
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wikidoc
ENO3
ENO3 Enolase 3 (ENO3), more commonly known as beta-enolase (ENO-β), is an enzyme that in humans is encoded by the ENO3 gene. This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regenerati...
ENO3 Enolase 3 (ENO3), more commonly known as beta-enolase (ENO-β), is an enzyme that in humans is encoded by the ENO3 gene. This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regenerat...
https://www.wikidoc.org/index.php/ENO3
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wikidoc
ENTJ
ENTJ ENTJ (Extroverted iNtuitive Thinking Judging) is one of the sixteen personality types from personality type systems based on C.G. Jung, of which the best-known is the Myers-Briggs Type Indicator (MBTI). Under 2 percent of the population rank as ENTJ. Referring to Keirsey, ENTJs belong to the temperament of the Rat...
ENTJ ENTJ (Extroverted iNtuitive Thinking Judging) is one of the sixteen personality types from personality type systems based on C.G. Jung, of which the best-known is the Myers-Briggs Type Indicator (MBTI). Under 2 percent of the population rank as ENTJ. Referring to Keirsey, ENTJs belong to the temperament of the Ra...
https://www.wikidoc.org/index.php/ENTJ
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wikidoc
EPN1
EPN1 Epsin-1 is a protein that in humans is encoded by the EPN1 gene. EPN1 is an endocytic accessory protein that interacts with EPS15 (MIM 600051), the alpha subunit of the clathrin adaptor AP2 (AP2A1; MIM 601026), and clathrin (see MIM 118960), as well as with other accessory proteins for the endocytosis of clathrin-...
EPN1 Epsin-1 is a protein that in humans is encoded by the EPN1 gene.[1][2][3] EPN1 is an endocytic accessory protein that interacts with EPS15 (MIM 600051), the alpha subunit of the clathrin adaptor AP2 (AP2A1; MIM 601026), and clathrin (see MIM 118960), as well as with other accessory proteins for the endocytosis of...
https://www.wikidoc.org/index.php/EPN1
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wikidoc
EPRS
EPRS Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene. # Gene Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. # Function Aminoacyl-tRNA synthetases are a class of enzymes tha...
EPRS Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene.[1][2] # Gene Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined.[2] # Function Aminoacyl-tRNA synthetases are a class of e...
https://www.wikidoc.org/index.php/EPRS
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wikidoc
EPS8
EPS8 Epidermal growth factor receptor kinase substrate 8 is an enzyme that in humans is encoded by the EPS8 gene. # Function This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Hi...
EPS8 Epidermal growth factor receptor kinase substrate 8 is an enzyme that in humans is encoded by the EPS8 gene.[1][2] # Function This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determi...
https://www.wikidoc.org/index.php/EPS8
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wikidoc
ERN1
ERN1 The serine/threonine-protein kinase/endoribonuclease inositol-requiring enzyme 1 α (IRE1α) is an enzyme that in humans is encoded by the ERN1 gene. # Function The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intri...
ERN1 The serine/threonine-protein kinase/endoribonuclease inositol-requiring enzyme 1 α (IRE1α) is an enzyme that in humans is encoded by the ERN1 gene.[1][2] # Function The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesse...
https://www.wikidoc.org/index.php/ERN1
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wikidoc
ESFJ
ESFJ ESFJ (Extroverted Sensing Feeling Judging) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ESFJs belong to the temperament of the Guardians and are called Providers. ESFJ are the best hosts/hostesses, they love to organi...
ESFJ ESFJ (Extroverted Sensing Feeling Judging) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ESFJs belong to the temperament of the Guardians and are called Providers. ESFJ are the best hosts/hostesses, they love to organ...
https://www.wikidoc.org/index.php/ESFJ
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wikidoc
ESFP
ESFP ESFP (Extroverted Sensing Feeling Perceiving) is one of the sixteen personality types which is used in the Myers-Briggs Type Indicator (MBTI) and is based on the well-known research of Carl Jung. Carl Jung first developed the theory that every person has their own psychological type. Myers and Briggs further devel...
ESFP ESFP (Extroverted Sensing Feeling Perceiving) is one of the sixteen personality types which is used in the Myers-Briggs Type Indicator (MBTI) and is based on the well-known research of Carl Jung. Carl Jung first developed the theory that every person has their own psychological type. Myers and Briggs further deve...
https://www.wikidoc.org/index.php/ESFP
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wikidoc
ESM1
ESM1 Endothelial cell-specific molecule 1 is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endoth...
ESM1 Endothelial cell-specific molecule 1 is a protein that in humans is encoded by the ESM1 gene.[1][2] This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in...
https://www.wikidoc.org/index.php/ESM1
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wikidoc
ESTJ
ESTJ ESTJ (Extroverted Sensing Thinking Judging) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ESTJs belong to the temperament of the guardians and are called "Supervisors". # Myers-Briggs Characteristics ESTJs are practic...
ESTJ ESTJ (Extroverted Sensing Thinking Judging) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ESTJs belong to the temperament of the guardians and are called "Supervisors". # Myers-Briggs Characteristics ESTJs are practi...
https://www.wikidoc.org/index.php/ESTJ
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wikidoc
ESTP
ESTP ESTP (Extroverted Sensing Thinking Perceiving) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ESTPs belong to the Artisan temperament and are called "Promoters". # Myers-Briggs Characteristics According to Myers-Briggs...
ESTP ESTP (Extroverted Sensing Thinking Perceiving) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ESTPs belong to the Artisan temperament and are called "Promoters". # Myers-Briggs Characteristics According to Myers-Brigg...
https://www.wikidoc.org/index.php/ESTP
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wikidoc
ETS1
ETS1 Protein C-ets-1 is a protein that in humans is encoded by the ETS1 gene. The protein encoded by this gene belongs to the ETS family of transcription factors. # Function There are 28 ETS genes in humans and 27 in mice. They bind the DNA via their winged-helix-turn-helix DNA binding motif known as the Ets domain t...
ETS1 Protein C-ets-1 is a protein that in humans is encoded by the ETS1 gene.[1] The protein encoded by this gene belongs to the ETS family of transcription factors.[2] # Function There are 28 ETS genes in humans and 27 in mice. They bind the DNA via their winged-helix-turn-helix DNA binding motif known as the Ets d...
https://www.wikidoc.org/index.php/ETS1
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wikidoc
ETV6
ETV6 ETV6 (i.e. translocation-Ets-leukemia virus) protein is a transcription factor that in humans is encoded by the ETV6 (previously known as TEL) gene. The ETV6 protein regulates the development and growth of diverse cell types, particularly those of hematological tissues. However, its gene, ETV6 frequently suffers v...
ETV6 ETV6 (i.e. translocation-Ets-leukemia virus) protein is a transcription factor that in humans is encoded by the ETV6 (previously known as TEL) gene. The ETV6 protein regulates the development and growth of diverse cell types, particularly those of hematological tissues. However, its gene, ETV6 frequently suffers ...
https://www.wikidoc.org/index.php/ETV6
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wikidoc
EVAR
EVAR # Overview Endovascular aneurysm repair (or endovascular aortic repair) (EVAR) is a type of endovascular surgery used to treat an abdominal aortic aneurysm (AAA) or thoracic aortic aneurysm, the procedure then specifically termed TEVAR (thoracic endovascular aortic/aneurysm repair). In certain occasions, a specia...
EVAR Template:Interventions infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Endovascular aneurysm repair (or endovascular aortic repair) (EVAR) is a type of endovascular surgery used to treat an abdominal aortic aneurysm (AAA) or thoracic aortic aneurysm, the procedure then specifically termed T...
https://www.wikidoc.org/index.php/EVAR
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wikidoc
EVI1
EVI1 Ecotropic viral integration site 1 is a human protein encoded by the EVI1 gene. EVI1 was first identified as a common retroviral integration site in AKXD murine myeloid tumors. It has since been identified in a plethora of other organisms, and seems to play a relatively conserved developmental role in embryogenes...
EVI1 Ecotropic viral integration site 1 is a human protein encoded by the EVI1 gene. EVI1 was first identified as a common retroviral integration site in AKXD murine myeloid tumors. It has since been identified in a plethora of other organisms, and seems to play a relatively conserved developmental role in embryogene...
https://www.wikidoc.org/index.php/EVI1
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wikidoc
EZH2
EZH2 Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme (EC 2.1.1.43) encoded by EZH2 gene, that participates in histone methylation and, ultimately, transcriptional repression. EZH2 catalyzes the addition of methyl groups to histone H3 at lysine 27, by using the cofactor S-adenosyl-L-met...
EZH2 Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme (EC 2.1.1.43) encoded by EZH2 gene, that participates in histone methylation and, ultimately, transcriptional repression.[1] EZH2 catalyzes the addition of methyl groups to histone H3 at lysine 27,[2] by using the cofactor S-adenosy...
https://www.wikidoc.org/index.php/EZH2
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wikidoc
Salt
Salt Salt from ancient Greek "άλς" (sea) is a mineral essential for animal life, composed primarily of sodium chloride. Salt for human consumption is produced in different forms: unrefined salt (such as sea salt), refined salt (table salt), and iodized salt. It is a crystalline solid, white, pale pink or light grey in ...
Salt Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Salt from ancient Greek "άλς" (sea) is a mineral essential for animal life, composed primarily of sodium chloride. Salt for human consumption is produced in different forms: unrefined salt (such as sea salt), refined salt (table salt), and iodized salt. It is a c...
https://www.wikidoc.org/index.php/Edible_salt
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wikidoc
Ovum
Ovum # Overview An ovum (plural ova) is a haploid female reproductive cell or gamete. The word is derived from Latin, meaning egg or egg cell. Both animals and embryophytes have ova. The term ovule is used for the young ovum of an animal, as well as the plant structure that carries the female gametophyte and egg cell ...
Ovum # Overview An ovum (plural ova) is a haploid female reproductive cell or gamete. The word is derived from Latin, meaning egg or egg cell. Both animals and embryophytes have ova. The term ovule is used for the young ovum of an animal, as well as the plant structure that carries the female gametophyte and egg cell ...
https://www.wikidoc.org/index.php/Egg_cell
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wikidoc
Enol
Enol Enols (also known as alkenols) are alkenes with a hydroxyl group affixed to one of the carbon atoms composing the double bond. Enols and carbonyl compounds (such as ketones and aldehydes) are in fact isomers; this is called keto-enol tautomerism: The enol form is shown on the left. It is usually unstable, does not...
Enol Enols (also known as alkenols) are alkenes with a hydroxyl group affixed to one of the carbon atoms composing the double bond. Enols and carbonyl compounds (such as ketones and aldehydes) are in fact isomers; this is called keto-enol tautomerism: The enol form is shown on the left. It is usually unstable, does no...
https://www.wikidoc.org/index.php/Enol
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wikidoc
Envy
Envy Envy may be defined as an emotion that "occurs when a person lacks another’s superior quality, achievement, or possession and either desires it or wishes that the other lacked it." It can also derive from a sense of low self-esteem that results from an upward social comparison threatening a person's self image: an...
Envy Template:Emotion Envy may be defined as an emotion that "occurs when a person lacks another’s superior quality, achievement, or possession and either desires it or wishes that the other lacked it."[1] It can also derive from a sense of low self-esteem that results from an upward social comparison threatening a pe...
https://www.wikidoc.org/index.php/Envy
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wikidoc
ErbB
ErbB # Overview The ErbB protein family or epidermal growth factor receptor (EGFR) family is a family of four structurally related receptor tyrosine kinases. Insufficient ErbB signaling in humans is associated with the development of neurodegenerative diseases, such as multiple sclerosis and Alzheimer's Disease. In mi...
ErbB # Overview The ErbB protein family or epidermal growth factor receptor (EGFR) family is a family of four structurally related receptor tyrosine kinases. Insufficient ErbB signaling in humans is associated with the development of neurodegenerative diseases, such as multiple sclerosis and Alzheimer's Disease.[1] In...
https://www.wikidoc.org/index.php/ErbB
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wikidoc
F13B
F13B Coagulation factor XIII B chain is a protein that in humans is encoded by the F13B gene. This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B sub...
F13B Coagulation factor XIII B chain is a protein that in humans is encoded by the F13B gene.[1][2] This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and ...
https://www.wikidoc.org/index.php/F13B