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wikidoc
FA2H
FA2H Fatty acid 2-hydroxylase is a protein that in humans is encoded by the FA2H gene. # Function This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural di...
FA2H Fatty acid 2-hydroxylase is a protein that in humans is encoded by the FA2H gene.[1] # Function This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structura...
https://www.wikidoc.org/index.php/FA2H
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wikidoc
FADD
FADD Fas-associated protein with death domain (FADD), also called MORT1, is encoded by the FADD gene on the 11q13.3 region of chromosome 11 in humans. FADD is an adaptor protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10 to form the death-i...
FADD Fas-associated protein with death domain (FADD), also called MORT1, is encoded by the FADD gene on the 11q13.3 region of chromosome 11 in humans.[1] FADD is an adaptor protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10 to form the dea...
https://www.wikidoc.org/index.php/FADD
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wikidoc
FAN1
FAN1 FANCD2/FANCI-associated nuclease 1 (KIAA1018) is an enzyme that in humans is encoded by the FAN1 gene. It is a structure dependent endonuclease and a member of the myotubularin-related class 1 cysteine-based protein tyrosine phosphatases. It is thought to play an important role in the Fanconi Anemia (FA) pathway. ...
FAN1 FANCD2/FANCI-associated nuclease 1 (KIAA1018) is an enzyme that in humans is encoded by the FAN1 gene. It is a structure dependent endonuclease and a member of the myotubularin-related class 1 cysteine-based protein tyrosine phosphatases. It is thought to play an important role in the Fanconi Anemia (FA) pathway....
https://www.wikidoc.org/index.php/FAN1
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wikidoc
FAT1
FAT1 Protocadherin FAT1 is a protein that in humans is encoded by the FAT1 gene. # Function This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group...
FAT1 Protocadherin FAT1 is a protein that in humans is encoded by the FAT1 gene.[1][2] # Function This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, ...
https://www.wikidoc.org/index.php/FAT1
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wikidoc
FCAR
FCAR Fc fragment of IgA receptor (FCAR) is a human gene that codes for the transmembrane receptor FcαRI, also known as CD89 (Cluster of Differentiation 89). FcαRI binds the heavy-chain constant region of Immunoglubulin A (IgA) antibodies. FcαRI is present on the cell surface of myeloid lineage cells, including neutroph...
FCAR Fc fragment of IgA receptor (FCAR) is a human gene[1] that codes for the transmembrane receptor FcαRI, also known as CD89 (Cluster of Differentiation 89). FcαRI binds the heavy-chain constant region of Immunoglubulin A (IgA) antibodies.[2] FcαRI is present on the cell surface of myeloid lineage cells, including n...
https://www.wikidoc.org/index.php/FCAR
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wikidoc
FEZ1
FEZ1 Fasciculation and elongation protein zeta-1 is a protein that in humans is encoded by the FEZ1 gene. This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the muta...
FEZ1 Fasciculation and elongation protein zeta-1 is a protein that in humans is encoded by the FEZ1 gene.[1][2][3] This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore t...
https://www.wikidoc.org/index.php/FEZ1
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wikidoc
FGD1
FGD1 FYVE, RhoGEF and PH domain-containing protein 1 (FGD1) also known as faciogenital dysplasia 1 protein (FGDY), zinc finger FYVE domain-containing protein 3 (ZFYVE3), or Rho/Rac guanine nucleotide exchange factor FGD1 (Rho/Rac GEF) is a protein that in humans is encoded by the FGD1 gene that lies on the X chromosome...
FGD1 FYVE, RhoGEF and PH domain-containing protein 1 (FGD1) also known as faciogenital dysplasia 1 protein (FGDY), zinc finger FYVE domain-containing protein 3 (ZFYVE3), or Rho/Rac guanine nucleotide exchange factor FGD1 (Rho/Rac GEF) is a protein that in humans is encoded by the FGD1 gene that lies on the X chromosom...
https://www.wikidoc.org/index.php/FGD1
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wikidoc
FGF1
FGF1 FGF1, also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene. It is synthesized as a 155 amino acid polypeptide, whose mature form is a non-glycosylated 17-18 kDa protein. Fibroblast growth factor protein was first purified in 1975, but soon afterw...
FGF1 FGF1, also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene.[1][2] It is synthesized as a 155 amino acid polypeptide, whose mature form is a non-glycosylated 17-18 kDa protein. Fibroblast growth factor protein was first purified in 1975, but soon...
https://www.wikidoc.org/index.php/FGF1
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wikidoc
FGF3
FGF3 INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene. # Function FGF-3 is a member of the fibroblast growth factor family. FGF3 binds to Fibroblast Growth Factor Receptor 3 (FGFR3) to serve as a negative regulator of bone growth during ossification. Effectively,...
FGF3 INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene.[1] # Function FGF-3 is a member of the fibroblast growth factor family. FGF3 binds to Fibroblast Growth Factor Receptor 3 (FGFR3) to serve as a negative regulator of bone growth during ossification. Effectiv...
https://www.wikidoc.org/index.php/FGF3
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wikidoc
FGF4
FGF4 Fibroblast growth factor 4 is a protein that in humans is encoded by the FGF4 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embr...
FGF4 Fibroblast growth factor 4 is a protein that in humans is encoded by the FGF4 gene.[1][2] The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes includi...
https://www.wikidoc.org/index.php/FGF4
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wikidoc
FGF5
FGF5 Fibroblast growth factor 5 is a protein that in humans is encoded by the FGF5 gene. The majority of FGF family members are glycosaminoglycan binding proteins which possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell grow...
FGF5 Fibroblast growth factor 5 is a protein that in humans is encoded by the FGF5 gene. The majority of FGF family members are glycosaminoglycan binding proteins which possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell gro...
https://www.wikidoc.org/index.php/FGF5
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wikidoc
FGF8
FGF8 Fibroblast growth factor 8 is a protein that in humans is encoded by the FGF8 gene. # Function The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, ...
FGF8 Fibroblast growth factor 8 is a protein that in humans is encoded by the FGF8 gene.[1][2] # Function The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological proc...
https://www.wikidoc.org/index.php/FGF8
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wikidoc
FGF9
FGF9 Glia-activating factor is a protein that in humans is encoded by the FGF9 gene. # Function The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, incl...
FGF9 Glia-activating factor is a protein that in humans is encoded by the FGF9 gene.[1][2] # Function The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processe...
https://www.wikidoc.org/index.php/FGF9
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wikidoc
FGL1
FGL1 Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene. Four splice variants exist for this gene. # Function Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like ...
FGL1 Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.[1][2] Four splice variants exist for this gene. # Function Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinoge...
https://www.wikidoc.org/index.php/FGL1
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wikidoc
FGL2
FGL2 Fibrinogen-like protein 2, also known as FGL2, is a protein which in humans is encoded by the FGL2 gene. # Structure FGL2 is a 439 amino acid secreted protein that is similar to the β- and γ-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The e...
FGL2 Fibrinogen-like protein 2, also known as FGL2, is a protein which in humans is encoded by the FGL2 gene.[1][2] # Structure FGL2 is a 439 amino acid secreted protein that is similar to the β- and γ-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED)...
https://www.wikidoc.org/index.php/FGL2
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wikidoc
FHIT
FHIT Bis(5'-adenosyl)-triphosphatase also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene. # Function FHIT is also known as human accelerated region 10. It may, therefore, have played a key role in differentiating humans from apes. This gene, a member of the his...
FHIT Bis(5'-adenosyl)-triphosphatase also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene.[1][2] # Function FHIT is also known as human accelerated region 10. It may, therefore, have played a key role in differentiating humans from apes.[3] This gene, a member ...
https://www.wikidoc.org/index.php/FHIT
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wikidoc
FHL1
FHL1 Four and a half LIM domains protein 1 is a protein that in humans is encoded by the FHL1 gene. # Structure LIM proteins, named for 'LIN11, ISL1, and MEC3,' are defined by the possession of a highly conserved double zinc finger motif called the LIM domain. # Role in muscle disorders FHL1 has been shown to be heav...
FHL1 Four and a half LIM domains protein 1 is a protein that in humans is encoded by the FHL1 gene.[1][2][3] # Structure LIM proteins, named for 'LIN11, ISL1, and MEC3,' are defined by the possession of a highly conserved double zinc finger motif called the LIM domain.[3] # Role in muscle disorders FHL1 has been sho...
https://www.wikidoc.org/index.php/FHL1
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wikidoc
FHL2
FHL2 Four and a half LIM domains protein 2 also known as FHL-2 is a protein that in humans is encoded by the FHL2 gene. LIM proteins contain a highly conserved double zinc finger motif called the LIM domain. # Function FHL-2 is thought to have a role in the assembly of extracellular membranes and may function as a lin...
FHL2 Four and a half LIM domains protein 2 also known as FHL-2 is a protein that in humans is encoded by the FHL2 gene.[1] LIM proteins contain a highly conserved double zinc finger motif called the LIM domain.[2] # Function FHL-2 is thought to have a role in the assembly of extracellular membranes and may function a...
https://www.wikidoc.org/index.php/FHL2
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wikidoc
FHL5
FHL5 Four and a half LIM domains protein 5 is a protein that in humans is encoded by the FHL5 gene. # Function The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CR...
FHL5 Four and a half LIM domains protein 5 is a protein that in humans is encoded by the FHL5 gene.[1] # Function The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function...
https://www.wikidoc.org/index.php/FHL5
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wikidoc
FIS1
FIS1 Mitochondrial fission 1 protein (FIS1) is a protein that in humans is encoded by the FIS1 gene on chromosome 7. This protein is a component of a mitochondrial complex, the ARCosome, that promotes mitochondrial fission. Its role in mitochondrial fission thus implicates it in the regulation of mitochondrial morphol...
FIS1 Mitochondrial fission 1 protein (FIS1) is a protein that in humans is encoded by the FIS1 gene on chromosome 7.[1][2][3] This protein is a component of a mitochondrial complex, the ARCosome, that promotes mitochondrial fission.[3][4] Its role in mitochondrial fission thus implicates it in the regulation of mitoc...
https://www.wikidoc.org/index.php/FIS1
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wikidoc
FLI1
FLI1 Friend leukemia integration 1 transcription factor (FLI1), also known as transcription factor ERGB, is a protein that in humans is encoded by the FLI1 gene, which is a proto-oncogene. # Function Fli-1 is a member of the ETS transcription factor family that was first identified in erythroleukemias induced by Frien...
FLI1 Friend leukemia integration 1 transcription factor (FLI1), also known as transcription factor ERGB, is a protein that in humans is encoded by the FLI1 gene, which is a proto-oncogene.[1][2][3] # Function Fli-1 is a member of the ETS transcription factor family that was first identified in erythroleukemias induce...
https://www.wikidoc.org/index.php/FLI1
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wikidoc
FLII
FLII Protein flightless-1 homolog is a protein that in humans is encoded by the FLII gene. This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and th...
FLII Protein flightless-1 homolog is a protein that in humans is encoded by the FLII gene.[1][2] This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain.[3] The protein is similar to a Drosophila protein involved in early embryogene...
https://www.wikidoc.org/index.php/FLII
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wikidoc
FLNA
FLNA Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene. # Function Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remod...
FLNA Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene.[1][2] # Function Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton...
https://www.wikidoc.org/index.php/FLNA
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wikidoc
FLNB
FLNB Filamin B, beta (FLNB), also known as Filamin B, beta (actin binding protein 278), is a cytoplasmic protein which in humans is encoded by the FLNB gene. FLNB regulates intracellular communication and signalling by cross-linking the protein actin to allow direct communication between the cell membrane and cytoskele...
FLNB Filamin B, beta (FLNB), also known as Filamin B, beta (actin binding protein 278), is a cytoplasmic protein which in humans is encoded by the FLNB gene. FLNB regulates intracellular communication and signalling by cross-linking the protein actin to allow direct communication between the cell membrane and cytoskel...
https://www.wikidoc.org/index.php/FLNB
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wikidoc
FMR1
FMR1 FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein called fragile X mental retardation protein, or FMRP. This protein, most commonly found in the brain, is essential for normal cognitive development and female reproductive function. Mutations of this gene can lead to fragile X syndrome,...
FMR1 FMR1 (fragile X mental retardation 1) is a human gene[1] that codes for a protein called fragile X mental retardation protein, or FMRP.[2] This protein, most commonly found in the brain, is essential for normal cognitive development and female reproductive function. Mutations of this gene can lead to fragile X sy...
https://www.wikidoc.org/index.php/FMR1
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wikidoc
FNTA
FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha is an enzyme that in humans is encoded by the FNTA gene. Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltr...
FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha is an enzyme that in humans is encoded by the FNTA gene.[1][2] Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylge...
https://www.wikidoc.org/index.php/FNTA
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wikidoc
RBM9
RBM9 RNA binding motif protein 9 (RBM9), also known as Rbfox2, is a protein which in humans is encoded by the RBM9 gene. # Function Rbfox2 is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative splicing in the ...
RBM9 RNA binding motif protein 9 (RBM9), also known as Rbfox2, is a protein which in humans is encoded by the RBM9 gene.[1] # Function Rbfox2 is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative splicing in ...
https://www.wikidoc.org/index.php/FOX-2
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wikidoc
FUT8
FUT8 Alpha-(1,6)-fucosyltransferase is an enzyme that in humans is encoded by the FUT8 gene. This enzyme belongs to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases ...
FUT8 Alpha-(1,6)-fucosyltransferase is an enzyme that in humans is encoded by the FUT8 gene.[1][2] This enzyme belongs to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransf...
https://www.wikidoc.org/index.php/FUT8
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wikidoc
FXR1
FXR1 Fragile X mental retardation syndrome-related protein 1 is a protein that in humans is encoded by the FXR1 gene. The protein encoded by this gene is an RNA binding protein that interacts with the functionally similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate wit...
FXR1 Fragile X mental retardation syndrome-related protein 1 is a protein that in humans is encoded by the FXR1 gene.[1][2][3] The protein encoded by this gene is an RNA binding protein that interacts with the functionally similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and ass...
https://www.wikidoc.org/index.php/FXR1
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wikidoc
FZD3
FZD3 Frizzled-3 is a protein that in humans is encoded by the FZD3 gene. # Function This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors a...
FZD3 Frizzled-3 is a protein that in humans is encoded by the FZD3 gene.[1][2][3] # Function This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled r...
https://www.wikidoc.org/index.php/FZD3
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wikidoc
FZD6
FZD6 Frizzled-6 is a protein that in humans is encoded by the FZD6 gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for WNT signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 transmembr...
FZD6 Frizzled-6 is a protein that in humans is encoded by the FZD6 gene.[1][2][3] Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for WNT signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 ...
https://www.wikidoc.org/index.php/FZD6
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wikidoc
Face
Face # Overview The face is the front part of the head and includes the hair, forehead, eyebrow, eyes, nose, ears, cheeks, mouth, lips, philtrum, teeth, skin, and chin. The face is used for expression, appearance, and identity amongst others. # The face as a means of recognition The face is the feature which best d...
Face Template:Infobox Anatomy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The face is the front part of the head and includes the hair, forehead, eyebrow, eyes, nose, ears, cheeks, mouth, lips, philtrum, teeth, skin, and chin.[1] The face is used for expression, appearance, and identity amongst oth...
https://www.wikidoc.org/index.php/Face
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wikidoc
Fear
Fear Fear is an emotional response to tangible and realistic dangers. Fear should be distinguished from anxiety, an emotion that often arises out of proportion to the actual threat or danger involved, and can be subjectively experienced without any specific attention to the threatening object. Most fear is usually con...
Fear Template:Emotion Fear is an emotional response to tangible and realistic dangers. Fear should be distinguished from anxiety, an emotion that often arises out of proportion to the actual threat or danger involved, and can be subjectively experienced without any specific attention to the threatening object. [1][2] ...
https://www.wikidoc.org/index.php/Fear
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wikidoc
Fern
Fern A fern is any one of a group of about 20,000 species of plants classified in the phylum or division Pteridophyta, also known as Filicophyta. The group is also referred to as Polypodiophyta, or Polypodiopsida when treated as a subdivision of tracheophyta (vascular plants). The study of ferns and other pteridophyte...
Fern A fern is any one of a group of about 20,000 species of plants classified in the phylum or division Pteridophyta, also known as Filicophyta. The group is also referred to as Polypodiophyta, or Polypodiopsida when treated as a subdivision of tracheophyta (vascular plants). The study of ferns and other pteridophyt...
https://www.wikidoc.org/index.php/Fern
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wikidoc
FiO2
FiO2 FiO2, in the field of medicine, is the fraction of inspired oxygen in a gas mixture. The FiO2 is expressed as a number from 0 (0%) to 1 (100%). The FiO2 of normal room air is 0.21 (21%). A patient's FiO2 may be varied through the use of different Venturi masks, in combination with varying oxygen flow rates. In a...
FiO2 FiO2, in the field of medicine, is the fraction of inspired oxygen in a gas mixture. The FiO2 is expressed as a number from 0 (0%) to 1 (100%). The FiO2 of normal room air is 0.21 (21%). A patient's FiO2 may be varied through the use of different Venturi masks, in combination with varying oxygen flow rates. In ...
https://www.wikidoc.org/index.php/FiO2
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wikidoc
Fig4
Fig4 Polyphosphoinositide phosphatase also known as phosphatidylinositol 3,5-bisphosphate 5-phosphatase or SAC domain-containing protein 3 (Sac3) is an enzyme that in humans is encoded by the FIG4 gene. Fig4 is an abbreviation for Factor-Induced Gene. # Function Sac3 protein belongs to a family of human phosphoinosit...
Fig4 Polyphosphoinositide phosphatase also known as phosphatidylinositol 3,5-bisphosphate 5-phosphatase or SAC domain-containing protein 3 (Sac3) is an enzyme that in humans is encoded by the FIG4 gene.[1] Fig4 is an abbreviation for Factor-Induced Gene.[2] # Function Sac3 protein belongs to a family of human phosph...
https://www.wikidoc.org/index.php/Fig4
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wikidoc
Flax
Flax Flax (also known as Common Flax or Linseed) is a member of the genus Linum in the family Linaceae. The New Zealand flax is unrelated. Flax is native to the region extending from the eastern Mediterranean to India and was probably first domesticated in the Fertile Crescent. It was extensively cultivated in ancient...
Flax Flax (also known as Common Flax or Linseed) is a member of the genus Linum in the family Linaceae. The New Zealand flax is unrelated. Flax is native to the region extending from the eastern Mediterranean to India and was probably first domesticated in the Fertile Crescent.[1] It was extensively cultivated in anc...
https://www.wikidoc.org/index.php/Flax
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wikidoc
Flea
Flea # Overview Flea is the common name for any of the small wingless insects of the order Siphonaptera (some authorities use the name Aphaniptera because it is older, but names above family rank need not follow the ICZN rules of priority, so most taxonomists use the more familiar name). Fleas are external parasites, ...
Flea # Overview Flea is the common name for any of the small wingless insects of the order Siphonaptera (some authorities use the name Aphaniptera because it is older, but names above family rank need not follow the ICZN rules of priority, so most taxonomists use the more familiar name). Fleas are external parasites, ...
https://www.wikidoc.org/index.php/Flea
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wikidoc
Foot
Foot The foot is a biological structure found in many animals that is used for locomotion. In many animals with feet, the foot is a separate organ at the terminal part of the leg made up of one or more segments or bones, generally including claws or nails. # The human foot ## Anatomy The major bones in the foot are: ...
Foot Template:Infobox Anatomy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] The foot is a biological structure found in many animals that is used for locomotion. In many animals with feet, the foot is a separate organ at the terminal part of the leg made up of one or more segments or bones, generally including cl...
https://www.wikidoc.org/index.php/Foot
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wikidoc
Frzb
Frzb Frzb (pronounced like the sport 'ultimate frisbee') is a Wnt-binding protein especially important in embryonic development. It is a competitor for the cell-surface G-protein receptor Frizzled. Frizzled is a tissue polarity gene in Drosophila melanogaster and encodes integral proteins that function as cell-surface...
Frzb Frzb (pronounced like the sport 'ultimate frisbee') is a Wnt-binding protein especially important in embryonic development. It is a competitor for the cell-surface G-protein receptor Frizzled. Frizzled is a tissue polarity gene in Drosophila melanogaster and encodes integral proteins that function as cell-surfac...
https://www.wikidoc.org/index.php/Frzb
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wikidoc
Fuel
Fuel # Overview Fuel is any material that is burnt or altered in order to obtain energy. Fuel releases its energy either through a chemical reaction means, such as combustion, or nuclear means, such as nuclear fission or nuclear fusion. An important property of a useful fuel is that its energy can be stored to be rele...
Fuel # Overview Fuel is any material that is burnt or altered in order to obtain energy.[1] Fuel releases its energy either through a chemical reaction means, such as combustion, or nuclear means, such as nuclear fission or nuclear fusion. An important property of a useful fuel is that its energy can be stored to be r...
https://www.wikidoc.org/index.php/Fuel
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wikidoc
G6PC
G6PC Glucose-6-phosphatase, catalytic subunit (glucose 6-phosphatase alpha) is an enzyme that in humans is encoded by the G6PC gene. Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzy...
G6PC Glucose-6-phosphatase, catalytic subunit (glucose 6-phosphatase alpha) is an enzyme that in humans is encoded by the G6PC gene.[1][2] Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a k...
https://www.wikidoc.org/index.php/G6PC
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wikidoc
GAB2
GAB2 GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene. GAB2 is a docking protein with a conserved, folded PH domain attached to the membrane and a large disordered region, which hosts interactions with signaling molecules. It is a member of the GAB/DOS family ...
GAB2 GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene.[1][2][3][4] GAB2 is a docking protein with a conserved, folded PH domain attached to the membrane and a large disordered region, which hosts interactions with signaling molecules. It is a member of the GA...
https://www.wikidoc.org/index.php/GAB2
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wikidoc
GAIL
GAIL GAIL (India) Limited, is India's largest natural gas transportation company, integrating all aspects of the Natural Gas value chain. # History The company (previously known as Gas Authority of India Ltd) is India's principal gas transmission and marketing company, was set up by the Government of India in August 1...
GAIL Template:Infobox Company GAIL (India) Limited, is India's largest natural gas transportation company, integrating all aspects of the Natural Gas value chain. # History The company (previously known as Gas Authority of India Ltd) is India's principal gas transmission and marketing company, was set up by the Gover...
https://www.wikidoc.org/index.php/GAIL
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wikidoc
GAS1
GAS1 Growth arrest-specific protein 1 is a protein that in humans is encoded by the GAS1 gene. # Function Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene. # Discovery The mouse ce...
GAS1 Growth arrest-specific protein 1 is a protein that in humans is encoded by the GAS1 gene.[1][2] # Function Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.[2] # Discovery Th...
https://www.wikidoc.org/index.php/GAS1
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wikidoc
GAS5
GAS5 Growth arrest-specific 5 is a non-protein coding RNA that in humans is encoded by the GAS5 gene. GAS5 noncoding RNA, which accumulates in growth arrested cells, acts as a decoy hormone response element for the glucocorticoid receptor (GR) and hence blocks the upregulation of gene expression by activated GR. A numb...
GAS5 Associate Editor(s)-in-Chief: Henry A. Hoff Growth arrest-specific 5 is a non-protein coding RNA that in humans is encoded by the GAS5 gene.[1][2] GAS5 noncoding RNA, which accumulates in growth arrested cells, acts as a decoy hormone response element for the glucocorticoid receptor (GR) and hence blocks the upr...
https://www.wikidoc.org/index.php/GAS5
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wikidoc
GAS6
GAS6 Growth arrest-specific 6, also known as GAS6, is a human gene coding for the Gas6 protein. It is similar to the Protein S with the same domain organization and 43% amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts. # Function Gas6 is a gamma-carboxyglutamic acid (Gl...
GAS6 Growth arrest-specific 6, also known as GAS6, is a human gene coding for the Gas6 protein. It is similar to the Protein S with the same domain organization and 43% amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts. # Function Gas6 is a gamma-carboxyglutamic acid (G...
https://www.wikidoc.org/index.php/GAS6
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wikidoc
GBP2
GBP2 Interferon-induced guanylate-binding protein 2 is a protein that in humans is encoded by the GBP2 gene. GBP2 is a gene related to the superfamily of large GTPases which can be induced mainly by interferon gamma. # Localization GBP2 gene is located in a various compartment in the cell: nucleus, cytosol and cytoske...
GBP2 Interferon-induced guanylate-binding protein 2 is a protein that in humans is encoded by the GBP2 gene.[1][2] GBP2 is a gene related to the superfamily of large GTPases which can be induced mainly by interferon gamma.[3] # Localization GBP2 gene is located in a various compartment in the cell: nucleus, cytosol a...
https://www.wikidoc.org/index.php/GBP2
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wikidoc
GBX2
GBX2 Homeobox protein GBX-2 is a protein that in humans is encoded by the GBX2 gene. # Function Gastrulation Brain Homeobox 2 (GBX2) is a homeobox gene involved in the normal development of rhombomeres 1-3 which is the mid/hindbrain region. This gene is a dosage dependent transcription factor involved in the regulatio...
GBX2 Homeobox protein GBX-2 is a protein that in humans is encoded by the GBX2 gene.[1][2][3] # Function Gastrulation Brain Homeobox 2 (GBX2) is a homeobox gene involved in the normal development of rhombomeres 1-3 which is the mid/hindbrain region. This gene is a dosage dependent transcription factor involved in the...
https://www.wikidoc.org/index.php/GBX2
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wikidoc
GCLC
GCLC Glutamate—cysteine ligase catalytic subunit is an enzyme that in humans is encoded by the GCLC gene. # Function Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and ...
GCLC Glutamate—cysteine ligase catalytic subunit is an enzyme that in humans is encoded by the GCLC gene.[1][2] # Function Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subun...
https://www.wikidoc.org/index.php/GCLC
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wikidoc
GCS1
GCS1 Mannosyl-oligosaccharide glucosidase is an enzyme that in humans is encoded by the MOGS gene. Glucosidase I is the first enzyme in the N-linked oligosaccharide processing pathway. GCS1 cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. GCS1 is located i...
GCS1 Mannosyl-oligosaccharide glucosidase is an enzyme that in humans is encoded by the MOGS gene.[1][2][3] Glucosidase I is the first enzyme in the N-linked oligosaccharide processing pathway. GCS1 cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. GCS1 is...
https://www.wikidoc.org/index.php/GCS1
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wikidoc
GCSH
GCSH Glycine cleavage system H protein, mitochondrial (abbreviated as GCSH) is a protein that in humans is encoded by the GCSH gene. Degradation of glycine is brought about by the glycine cleavage system (GCS), which is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase),...
GCSH Glycine cleavage system H protein, mitochondrial (abbreviated as GCSH) is a protein that in humans is encoded by the GCSH gene.[1][2][3] Degradation of glycine is brought about by the glycine cleavage system (GCS), which is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decar...
https://www.wikidoc.org/index.php/GCSH
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wikidoc
GDF2
GDF2 Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a protein that in humans is encoded by the GDF2 gene. GDF2 belongs to the transforming growth factor beta superfamily. # Structure GDF2 contains an N-terminal TGF-beta-like pro-peptide (prodomain) (residues 56–257) and a C-...
GDF2 Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a protein that in humans is encoded by the GDF2 gene.[1] GDF2 belongs to the transforming growth factor beta superfamily. # Structure GDF2 contains an N-terminal TGF-beta-like pro-peptide (prodomain) (residues 56–257) and ...
https://www.wikidoc.org/index.php/GDF2
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wikidoc
GDF3
GDF3 Growth differentiation factor-3 (GDF3), also known as Vg-related gene 2 (Vgr-2) is protein that in humans is encoded by the GDF3 gene. GDF3 belongs to the transforming growth factor beta (TGF-β) superfamily. It has high similarity to other TGF-β superfamily members including Vg1 (found in frogs) and GDF1. # Tissu...
GDF3 Growth differentiation factor-3 (GDF3), also known as Vg-related gene 2 (Vgr-2) is protein that in humans is encoded by the GDF3 gene.[1] GDF3 belongs to the transforming growth factor beta (TGF-β) superfamily. It has high similarity to other TGF-β superfamily members including Vg1 (found in frogs) and GDF1.[1] ...
https://www.wikidoc.org/index.php/GDF3
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wikidoc
GDF5
GDF5 Growth/differentiation factor 5 is a protein that in humans is encoded by the GDF5 gene. The protein encoded by this gene is closely related to the bone morphogenetic protein (BMP) family and is a member of the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site...
GDF5 Growth/differentiation factor 5 is a protein that in humans is encoded by the GDF5 gene.[1][2][3] The protein encoded by this gene is closely related to the bone morphogenetic protein (BMP) family and is a member of the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic proce...
https://www.wikidoc.org/index.php/GDF5
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wikidoc
GDF6
GDF6 Growth differentiation factor 6 (GDF6) is a protein that in humans is encoded by the GDF6 gene. # Function GDF6 belongs to the transforming growth factor beta superfamily and may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins, and control eye development. Growth differentiatio...
GDF6 Growth differentiation factor 6 (GDF6) is a protein that in humans is encoded by the GDF6 gene.[1] # Function GDF6 belongs to the transforming growth factor beta superfamily and may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins,[2] and control eye development.[3][4] Growth d...
https://www.wikidoc.org/index.php/GDF6
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wikidoc
GDI1
GDI1 Rab GDP dissociation inhibitor alpha is a protein that in humans is encoded by the GDI1 gene. # Function GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking ...
GDI1 Rab GDP dissociation inhibitor alpha is a protein that in humans is encoded by the GDI1 gene.[1][2] # Function GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular traff...
https://www.wikidoc.org/index.php/GDI1
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wikidoc
GFER
GFER Growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae), also known as GFER, or Hepatopoietin is a protein which in humans is encoded by the GFER gene. This gene is also known as essential for respiration and vegatative growth, augmenter of liver regeneration, and growth factor of Erv1-like/He...
GFER Growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae), also known as GFER, or Hepatopoietin is a protein which in humans is encoded by the GFER gene. This gene is also known as essential for respiration and vegatative growth, augmenter of liver regeneration, and growth factor of Erv1-like/H...
https://www.wikidoc.org/index.php/GFER
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wikidoc
GFM1
GFM1 Elongation factor G 1, mitochondrial is a protein that in humans is encoded by the GFM1 gene. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a br...
GFM1 Elongation factor G 1, mitochondrial is a protein that in humans is encoded by the GFM1 gene.[1][2][3] Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system le...
https://www.wikidoc.org/index.php/GFM1
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wikidoc
GGA1
GGA1 ADP-ribosylation factor-binding protein GGA1 is a protein that in humans is encoded by the GGA1 gene. This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins betw...
GGA1 ADP-ribosylation factor-binding protein GGA1 is a protein that in humans is encoded by the GGA1 gene.[1][2][3] This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of pro...
https://www.wikidoc.org/index.php/GGA1
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wikidoc
GGA2
GGA2 ADP-ribosylation factor-binding protein GGA2 is a protein that in humans is encoded by the GGA2 gene. # Function This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins betwee...
GGA2 ADP-ribosylation factor-binding protein GGA2 is a protein that in humans is encoded by the GGA2 gene.[1][2][3] # Function This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of prote...
https://www.wikidoc.org/index.php/GGA2
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wikidoc
GIT2
GIT2 ARF GTPase-activating protein GIT2 is an enzyme that in humans is encoded by the GIT2 gene. # Function This gene encodes a member of the GIT protein family. GIT proteins interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. This gene u...
GIT2 ARF GTPase-activating protein GIT2 is an enzyme that in humans is encoded by the GIT2 gene.[1][2][3] # Function This gene encodes a member of the GIT protein family. GIT proteins interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. T...
https://www.wikidoc.org/index.php/GIT2
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wikidoc
GJA1
GJA1 Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the GJA1 gene on chromosome 6. As a connexin, GJA1 is a component of gap junctions, which allow for gap junction intercellular communication (GJIC) between cells to regulate cell death, proliferation, a...
GJA1 Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the GJA1 gene on chromosome 6.[1][2][3] As a connexin, GJA1 is a component of gap junctions, which allow for gap junction intercellular communication (GJIC) between cells to regulate cell death, prolif...
https://www.wikidoc.org/index.php/GJA1
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wikidoc
GJB2
GJB2 Gap junction beta-2 protein (GJB2), also known as connexin 26 (Cx26) — is a protein that in humans is encoded by the GJB2 gene. # Clinical significance Defects in this gene lead to the most common form of congenital deafness in developed countries, called DFNB1 (also known as connexin 26 deafness or GJB2-related ...
GJB2 Gap junction beta-2 protein (GJB2), also known as connexin 26 (Cx26) — is a protein that in humans is encoded by the GJB2 gene. # Clinical significance Defects in this gene lead to the most common form of congenital deafness in developed countries, called DFNB1 (also known as connexin 26 deafness or GJB2-related...
https://www.wikidoc.org/index.php/GJB2
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wikidoc
GJB6
GJB6 Gap junction beta-6 protein (GJB6), also known as connexin 30 (Cx30) — is a protein that in humans is encoded by the GJB6 gene. Connexin 30 (Cx30) is one of several gap junction proteins expressed in the inner ear. Mutations in gap junction genes have been found to lead to both syndromic and nonsyndromic deafnes...
GJB6 Gap junction beta-6 protein (GJB6), also known as connexin 30 (Cx30) — is a protein that in humans is encoded by the GJB6 gene.[1][2][3] Connexin 30 (Cx30) is one of several gap junction proteins expressed in the inner ear.[4] Mutations in gap junction genes have been found to lead to both syndromic and nonsynd...
https://www.wikidoc.org/index.php/GJB6
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wikidoc
GJC2
GJC2 Gap junction gamma-2 (GJC2), also known as connexin-46.6 (Cx46.6) and connexin-47 (Cx47) and gap junction alpha-12 (GJA12), is a protein that in humans is encoded by the GJC2 gene. # Function This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and ...
GJC2 Gap junction gamma-2 (GJC2), also known as connexin-46.6 (Cx46.6) and connexin-47 (Cx47) and gap junction alpha-12 (GJA12), is a protein that in humans is encoded by the GJC2 gene.[1] # Function This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins ...
https://www.wikidoc.org/index.php/GJC2
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wikidoc
GJC3
GJC3 Gap junction gamma-3, also known as connexin-29 (Cx29) or gap junction epsilon-1 (GJE1), is a protein that in humans is encoded by the GJC3 gene. GJC3 is a conexin. # Function This gene encodes a gap junction protein. The encoded protein is known as a connexin, most of which form gap junctions that provide direct...
GJC3 Gap junction gamma-3, also known as connexin-29 (Cx29) or gap junction epsilon-1 (GJE1), is a protein that in humans is encoded by the GJC3 gene.[1] GJC3 is a conexin. # Function This gene encodes a gap junction protein. The encoded protein is known as a connexin, most of which form gap junctions that provide di...
https://www.wikidoc.org/index.php/GJC3
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wikidoc
GLB1
GLB1 Galactosidase, beta 1, also known as GLB1, is a protein which in humans is encoded by the GLB1 gene. The GLB1 protein is a beta-galactosidase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates. The GLB1 gene also encodes an elastin binding protein. In corn (Zea mays), Gl...
GLB1 Galactosidase, beta 1, also known as GLB1, is a protein which in humans is encoded by the GLB1 gene.[1][2] The GLB1 protein is a beta-galactosidase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates.[3] The GLB1 gene also encodes an elastin binding protein.[4] In corn (...
https://www.wikidoc.org/index.php/GLB1
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wikidoc
GLI1
GLI1 Zinc finger protein GLI1 also known as glioma-associated oncogene is a protein that in humans is encoded by the GLI1 gene. It was originally isolated from human glioblastoma cells. # Function The Gli proteins are the effectors of Hedgehog (Hh) signaling and have been shown to be involved in cell fate determinati...
GLI1 Zinc finger protein GLI1 also known as glioma-associated oncogene is a protein that in humans is encoded by the GLI1 gene. It was originally isolated from human glioblastoma cells.[1] # Function The Gli proteins are the effectors of Hedgehog (Hh) signaling and have been shown to be involved in cell fate determi...
https://www.wikidoc.org/index.php/GLI1
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wikidoc
GLI2
GLI2 Zinc finger protein GLI2 also known as GLI family zinc finger 2 is a protein that in humans is encoded by the GLI2 gene. The protein encoded by this gene is a transcription factor. GLI2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcrip...
GLI2 Zinc finger protein GLI2 also known as GLI family zinc finger 2 is a protein that in humans is encoded by the GLI2 gene.[1] The protein encoded by this gene is a transcription factor.[2] GLI2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as tr...
https://www.wikidoc.org/index.php/GLI2
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wikidoc
GLI3
GLI3 Zinc finger protein GLI3 is a protein that in humans is encoded by the GLI3 gene. This gene encodes a protein that belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein e...
GLI3 Zinc finger protein GLI3 is a protein that in humans is encoded by the GLI3 gene.[1][2] This gene encodes a protein that belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The pr...
https://www.wikidoc.org/index.php/GLI3
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wikidoc
GLMN
GLMN Glomulin is a protein that in humans is encoded by the GLMN gene. This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also ...
GLMN Glomulin is a protein that in humans is encoded by the GLMN gene.[1][2] This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations...
https://www.wikidoc.org/index.php/GLMN
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wikidoc
GLS2
GLS2 Glutaminase 2 (liver, mitochondrial) is a protein that in humans is encoded by the GLS2 gene. # Structure The GLS2 gene is on the 12th chromosome in humans, with its specific location being 12q13.3. It contains 19 exons. # Function GLS2 is a part of the glutaminase family. The protein encoded by this gene is a m...
GLS2 Glutaminase 2 (liver, mitochondrial) is a protein that in humans is encoded by the GLS2 gene.[1] # Structure The GLS2 gene is on the 12th chromosome in humans, with its specific location being 12q13.3. It contains 19 exons.[1] # Function GLS2 is a part of the glutaminase family. The protein encoded by this gene...
https://www.wikidoc.org/index.php/GLS2
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wikidoc
GM2A
GM2A GM2 ganglioside activator also known as GM2A is a protein which in humans is encoded by the GM2A gene. # Function The protein encoded by this gene is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together with GM2...
GM2A GM2 ganglioside activator also known as GM2A is a protein which in humans is encoded by the GM2A gene.[1][2] # Function The protein encoded by this gene is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together w...
https://www.wikidoc.org/index.php/GM2A
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wikidoc
GNAQ
GNAQ Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with GNA11 (its paralogue), it functions as a Gq alpha subunit. # Function Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane d...
GNAQ Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene.[1] Together with GNA11 (its paralogue), it functions as a Gq alpha subunit.[2] # Function Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmem...
https://www.wikidoc.org/index.php/GNAQ
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wikidoc
GNAZ
GNAZ Guanine nucleotide-binding protein G(z) subunit alpha is a protein that in humans is encoded by the GNAZ gene. # Function The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systems. This encoded protein may play a role in maintai...
GNAZ Guanine nucleotide-binding protein G(z) subunit alpha is a protein that in humans is encoded by the GNAZ gene.[1][2] # Function The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systems. This encoded protein may play a role in ...
https://www.wikidoc.org/index.php/GNAZ
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wikidoc
GNB1
GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene. # Function Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subun...
GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene.[1] # Function Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma s...
https://www.wikidoc.org/index.php/GNB1
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wikidoc
GNB5
GNB5 Guanine nucleotide-binding protein subunit beta-5 is a protein that in humans is encoded by the GNB5 gene. Alternatively spliced transcript variants encoding different isoforms exist. # Function Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector...
GNB5 Guanine nucleotide-binding protein subunit beta-5 is a protein that in humans is encoded by the GNB5 gene.[1] Alternatively spliced transcript variants encoding different isoforms exist.[2] # Function Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and e...
https://www.wikidoc.org/index.php/GNB5
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wikidoc
GNG2
GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene. Heterotrimeric G proteins play vital roles in cellular responses to external signals. The specificity of a G protein-receptor interaction is primarily mediated by the gamma subunit. # Interac...
GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene.[1][2] Heterotrimeric G proteins play vital roles in cellular responses to external signals. The specificity of a G protein-receptor interaction is primarily mediated by the gamma subunit.[sup...
https://www.wikidoc.org/index.php/GNG2
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wikidoc
GNLY
GNLY Granulysin, also known as GNLY, is a protein which in humans is encoded by the GNLY gene. # Function Granulysin is a protein present in cytotoxic granules of cytotoxic T cells and natural killer cells. Granulysin is a member of the saposin-like protein (SAPLIP) family and is released from cytotoxic T cells upon a...
GNLY Granulysin, also known as GNLY, is a protein which in humans is encoded by the GNLY gene.[1] # Function Granulysin is a protein present in cytotoxic granules of cytotoxic T cells and natural killer cells. Granulysin is a member of the saposin-like protein (SAPLIP) family and is released from cytotoxic T cells up...
https://www.wikidoc.org/index.php/GNLY
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wikidoc
GNMT
GNMT Glycine N-methyltransferase is an enzyme that in humans is encoded by the GNMT gene. # Discovery The enzyme was first described by Blumenstein and Williams (1960) in guinea pig liver. However, this enzyme was not purified until 1972 in the rabbit liver by Kerr. In 1984, Cook and Wagner demonstrated that a liver c...
GNMT Glycine N-methyltransferase is an enzyme that in humans is encoded by the GNMT gene.[1][2][3] # Discovery The enzyme was first described by Blumenstein and Williams (1960) in guinea pig liver.[4] However, this enzyme was not purified until 1972 in the rabbit liver by Kerr.[5] In 1984, Cook and Wagner demonstrate...
https://www.wikidoc.org/index.php/GNMT
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wikidoc
GOPC
GOPC Golgi-associated PDZ and coiled-coil motif-containing protein is a protein that in humans is encoded by the GOPC gene. PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. # Interactions GOPC has ...
GOPC Golgi-associated PDZ and coiled-coil motif-containing protein is a protein that in humans is encoded by the GOPC gene.[1][2][3] PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMI...
https://www.wikidoc.org/index.php/GOPC
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wikidoc
GOT1
GOT1 Aspartate aminotransferase, cytoplasmic is an enzyme that in humans is encoded by the GOT1 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and ...
GOT1 Aspartate aminotransferase, cytoplasmic is an enzyme that in humans is encoded by the GOT1 gene.[1][2] Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the ur...
https://www.wikidoc.org/index.php/GOT1
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wikidoc
GOT2
GOT2 Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism a...
GOT2 Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism ...
https://www.wikidoc.org/index.php/GOT2
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wikidoc
GPER
GPER G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the GPER gene. GPER binds to and is activated by the female sex hormone estradiol and is responsible for some of the rapid effects that estradiol has on cells. # Discovery T...
GPER G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the GPER gene.[1] GPER binds to and is activated by the female sex hormone estradiol and is responsible for some of the rapid effects that estradiol has on cells. # Discove...
https://www.wikidoc.org/index.php/GPER
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wikidoc
GPVI
GPVI Glycoprotein VI (platelet) also known as GPVI is a glycoprotein receptor for collagen which is expressed in platelets. In humans, glycoprotein VI is encoded by the GPVI gene. GPVI was first cloned in 2000 by several groups including that of Martine Jandrot-Perrus from INSERM. # Function Glycoprotein VI (GP6) is ...
GPVI Glycoprotein VI (platelet) also known as GPVI is a glycoprotein receptor for collagen which is expressed in platelets. In humans, glycoprotein VI is encoded by the GPVI gene.[1] GPVI was first cloned in 2000 by several groups including that of Martine Jandrot-Perrus from INSERM. # Function Glycoprotein VI (GP6)...
https://www.wikidoc.org/index.php/GPVI
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wikidoc
GPX1
GPX1 Glutathione peroxidase 1, also known as GPx1, is an enzyme that in humans is encoded by the GPX1 gene on chromosome 3. This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes i...
GPX1 Glutathione peroxidase 1, also known as GPx1, is an enzyme that in humans is encoded by the GPX1 gene on chromosome 3.[1] This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzym...
https://www.wikidoc.org/index.php/GPX1
9bf440d98587a5c7809e34f5f4748826b1589a3b
wikidoc
GPX4
GPX4 Glutathione peroxidase 4, also known as GPX4, is an enzyme that in humans is encoded by the GPX4 gene. GPX4 is a phospholipid hydroperoxidase that protects cells against membrane lipid peroxidation. # Function The antioxidant enzyme glutathione peroxidase 4 (GPx4) belongs to the family of glutathione peroxidase...
GPX4 Glutathione peroxidase 4, also known as GPX4, is an enzyme that in humans is encoded by the GPX4 gene.[1] GPX4 is a phospholipid hydroperoxidase that protects cells against membrane lipid peroxidation. # Function The antioxidant enzyme glutathione peroxidase 4 (GPx4) belongs to the family of glutathione peroxi...
https://www.wikidoc.org/index.php/GPX4
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wikidoc
GRAP
GRAP GRB2-related adapter protein is a protein that in humans is encoded by the GRAP gene. This gene encodes a member of the GRB2/Sem5 (C. elegans homolog)/Drk (Drosophila homolog) family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain in...
GRAP GRB2-related adapter protein is a protein that in humans is encoded by the GRAP gene.[1][2][3] This gene encodes a member of the GRB2/Sem5 (C. elegans homolog)/Drk (Drosophila homolog) family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2...
https://www.wikidoc.org/index.php/GRAP
2e5e26d44b1cbc82a26f87c1deb304f725839f95
wikidoc
GRB2
GRB2 Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the GRB2 gene. The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and...
GRB2 Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the GRB2 gene.[1][2] The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 dom...
https://www.wikidoc.org/index.php/GRB2
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wikidoc
GRB7
GRB7 Growth factor receptor-bound protein 7, also known as GRB7, is a protein that in humans is encoded by the GRB7 gene. # Function The product of this gene belongs to a small family of adaptor proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a ...
GRB7 Growth factor receptor-bound protein 7, also known as GRB7, is a protein that in humans is encoded by the GRB7 gene.[1][2] # Function The product of this gene belongs to a small family of adaptor proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene enc...
https://www.wikidoc.org/index.php/GRB7
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wikidoc
GYPA
GYPA Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene. GYPA has also recently been designated CD235a (cluster of differentiation 235a). # Function Glycophorins A (GYPA; this protein) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane...
GYPA Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene.[1] GYPA has also recently been designated CD235a (cluster of differentiation 235a). # Function Glycophorins A (GYPA; this protein) and B (GYPB) are major sialoglycoproteins of the human erythrocyte memb...
https://www.wikidoc.org/index.php/GYPA
ca9f5ef07db9ce50a1f6a1af8a71cf6e04a8165f
wikidoc
GYPB
GYPB Glycophorin B (MNS blood group) (gene designation GYPB) also known as sialoglycoprotein delta and SS-active sialoglycoprotein is a protein which in humans is encoded by the GYPB gene. GYPB has also recently been designated CD235b (cluster of differentiation 235b). # Function Glycophorin A (GYPA) and B (GYPB; this...
GYPB Glycophorin B (MNS blood group) (gene designation GYPB) also known as sialoglycoprotein delta and SS-active sialoglycoprotein is a protein which in humans is encoded by the GYPB gene.[1] GYPB has also recently been designated CD235b (cluster of differentiation 235b). # Function Glycophorin A (GYPA) and B (GYPB; ...
https://www.wikidoc.org/index.php/GYPB
83e9b80404422ef8063ce52789451bad8b20dc04
wikidoc
Gill
Gill A gill is a respiration organ that functions for the extraction of oxygen from water and the excretion of carbon dioxide. Unlike many small aquatic animals, which can absorb oxygen through the entire surface of their bodies, more complex aquatic organisms have gills specially formed to present an adequate surface ...
Gill A gill is a respiration organ that functions for the extraction of oxygen from water and the excretion of carbon dioxide. Unlike many small aquatic animals, which can absorb oxygen through the entire surface of their bodies, more complex aquatic organisms have gills specially formed to present an adequate surface...
https://www.wikidoc.org/index.php/Gill
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wikidoc
Gli2
Gli2 Gli2 is a transcriptional activator and repressor of which there are four isoforms; Gli2 alpha, beta, gamma and delta. C-terminal transcriptional activator and N-terminal repressor regions have been identified in both Gli2 and Gli3. However, the N-terminal part of human Gli2 is much smaller than its mouse or fro...
Gli2 Gli2 is a transcriptional activator and repressor of which there are four isoforms; Gli2 alpha, beta, gamma and delta.[1] C-terminal transcriptional activator and N-terminal repressor regions have been identified in both Gli2 and Gli3.[2] However, the N-terminal part of human Gli2 is much smaller than its mouse...
https://www.wikidoc.org/index.php/Gli2
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wikidoc
Gli3
Gli3 Gli3 is a known transcriptional repressor but may also have a positive transcriptional function. Gli3 represses dHand and Germlin which are involved in developing digits There is evidence that Shh-controlled processing (e.g cleavage) regulates transcriptional activity of Gli3 similarly to that of CI. Gli3 mutan...
Gli3 Gli3 is a known transcriptional repressor but may also have a positive transcriptional function.[1][2] Gli3 represses dHand and Germlin which are involved in developing digits[3] There is evidence that Shh-controlled processing (e.g cleavage) regulates transcriptional activity of Gli3 similarly to that of CI.[4...
https://www.wikidoc.org/index.php/Gli3
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wikidoc
Gram
Gram The gram (sometimes gramme in British English, although gram prevails), (Greek/Latin root grámma); symbol g, is a unit of mass. Originally defined as "the absolute weight of a volume of pure water equal to the cube of the hundredth part of a metre, and at the temperature of melting ice" (later 4 °C), a gram is now...
Gram Template:Units Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] The gram (sometimes gramme in British English, although gram prevails), (Greek/Latin root grámma); symbol g, is a unit of mass. Originally defined as "the absolute weight of a volume of pure water equal to the cube of the hundredth part of a metre,...
https://www.wikidoc.org/index.php/Gram
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wikidoc
Gurn
Gurn A gurn is a distorted facial expression, and a verb to describe the action. A typical gurn might involve projecting the lower jaw as far forward and up as possible, and covering the upper lip with the lower lip. The English Dialect Dictionary, compiled by Joseph Wright, defines the word gurn as 'to snarl as a dog;...
Gurn A gurn is a distorted facial expression, and a verb to describe the action. A typical gurn might involve projecting the lower jaw as far forward and up as possible, and covering the upper lip with the lower lip. The English Dialect Dictionary, compiled by Joseph Wright, defines the word gurn as 'to snarl as a dog...
https://www.wikidoc.org/index.php/Gurn
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wikidoc
H1N2
H1N2 H1N2 is a subtype of the species Influenza A virus (sometimes called bird flu virus). It is currently endemic in both human and pig populations. H1N1, H1N2, and H3N2 are the only known Influenza A virus subtypes currently circulating among humans. The new A(H1N2) strain appears to have resulted from the reassort...
H1N2 H1N2 is a subtype of the species Influenza A virus (sometimes called bird flu virus). It is currently endemic in both human and pig populations. H1N1, H1N2, and H3N2 are the only known Influenza A virus subtypes currently circulating among humans. The new A(H1N2) strain appears to have resulted from the reassor...
https://www.wikidoc.org/index.php/H1N2
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wikidoc
H3N8
H3N8 H3N8 is a subtype of the species Influenza A virus (sometimes called bird flu virus). H3N8 is now endemic in birds, horses and dogs. H3N8 is suspected of causing a human pandemic in either 1889 or 1900. Sources differ; some say the 1889 pandemic was caused H2N2. The experts also differ on exactly how sure we can ...
H3N8 Template:Flu H3N8 is a subtype of the species Influenza A virus (sometimes called bird flu virus). H3N8 is now endemic in birds, horses and dogs. H3N8 is suspected of causing a human pandemic in either 1889 or 1900. Sources differ; some say the 1889 pandemic was caused H2N2. The experts also differ on exactly ho...
https://www.wikidoc.org/index.php/H3N8