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wikidoc
H5N2
H5N2 H5N2 is a subtype of the species Influenzavirus A (avian influenza virus or bird flu virus). A highly pathogenic strain of H5N2 caused flu outbreaks with significant spread to numerous farms, resulting in great economic losses in 1983 in Pennsylvania, USA in chickens and turkeys, in 1994 in Mexico in chickens and ...
H5N2 Template:Flu H5N2 is a subtype of the species Influenzavirus A (avian influenza virus or bird flu virus). A highly pathogenic strain of H5N2 caused flu outbreaks with significant spread to numerous farms, resulting in great economic losses in 1983 in Pennsylvania, USA in chickens and turkeys, in 1994 in Mexico in...
https://www.wikidoc.org/index.php/H5N2
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wikidoc
H5N8
H5N8 H5N8 is a subtype of the species Influenza A virus (sometimes called bird flu virus). A highly pathogenic strain of it called A/turkey/Ireland/1378/83 caused a minor flu outbreak in 1983 in Ireland in turkeys. # Sources - ↑ "Avian influenza A(H5N1)- update 31: Situation (poultry) in Asia: need for a long-term re...
H5N8 Template:Flu H5N8 is a subtype of the species Influenza A virus (sometimes called bird flu virus). A highly pathogenic strain of it called A/turkey/Ireland/1378/83 caused a minor flu outbreak in 1983 in Ireland in turkeys.[1][2] # Sources - ↑ "Avian influenza A(H5N1)- update 31: Situation (poultry) in Asia: nee...
https://www.wikidoc.org/index.php/H5N8
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wikidoc
H7N2
H7N2 H7N2 is a subtype of the species Influenza A virus (sometimes called bird flu virus). # Outbreaks of H7N2 One person Virginia, US in 2002 and one person in New York, US, in 2003 were found to have serologic evidence of infection from H7N2; both fully recovered. In February 2004, an outbreak of low pathogenic avi...
H7N2 H7N2 is a subtype of the species Influenza A virus (sometimes called bird flu virus). # Outbreaks of H7N2 One person Virginia, US in 2002 and one person in New York, US, in 2003 were found to have serologic evidence of infection from H7N2; both fully recovered. In February 2004, an outbreak of low pathogenic av...
https://www.wikidoc.org/index.php/H7N2
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wikidoc
H7N3
H7N3 H7N3 is a subtype of the species Influenza A virus (sometimes called bird flu virus). In North America, the presence of H7N3 was confirmed at several poultry farms in British Columbia in February 2004. As of April 2004, 18 farms had been quarantined to halt the spread of the virus. Two cases of humans infected ...
H7N3 Template:Flu H7N3 is a subtype of the species Influenza A virus (sometimes called bird flu virus). In North America, the presence of H7N3 was confirmed at several poultry farms in British Columbia in February 2004. As of April 2004, 18 farms had been quarantined to halt the spread of the virus. Two cases of hu...
https://www.wikidoc.org/index.php/H7N3
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wikidoc
HARS
HARS Histidyl-tRNA synthetase (HARS) also known as histidine-tRNA ligase, is an enzyme which in humans is encoded by the HARS gene. # Function Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to t...
HARS Histidyl-tRNA synthetase (HARS) also known as histidine-tRNA ligase, is an enzyme which in humans is encoded by the HARS gene.[1][2] # Function Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belon...
https://www.wikidoc.org/index.php/HARS
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wikidoc
HAS1
HAS1 Hyaluronan synthase 1 is an enzyme that in humans is encoded by the HAS1 gene. # Structure Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of ...
HAS1 Hyaluronan synthase 1 is an enzyme that in humans is encoded by the HAS1 gene.[1][2] # Structure Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consi...
https://www.wikidoc.org/index.php/HAS1
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wikidoc
HATS
HATS # Objective To assess the effects of lipid-lowering drugs and/or antioxidant vitamins on progression or regression of coronary heart disease as measured by quantitative angiography in patients with low high density lipoprotein (HDL) cholesterol. # Methods HDL-Atherosclerosis Treatment Study (HATS) was a randomiz...
HATS Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Objective To assess the effects of lipid-lowering drugs and/or antioxidant vitamins on progression or regression of coronary heart disease as measured by quantitative angiography in patients with low high density lipoprotein (HDL) cholesterol. # Methods HDL-A...
https://www.wikidoc.org/index.php/HATS
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wikidoc
HAX1
HAX1 HCLS1-associated protein X-1 is a protein that in humans is encoded by the HAX1 gene. The protein encoded by this gene is known to associate with HS1, a substrate of Src family tyrosine kinases. It also interacts with the product of PKD2 gene, mutations in which are associated with autosomal-dominant polycystic ki...
HAX1 HCLS1-associated protein X-1 is a protein that in humans is encoded by the HAX1 gene.[1][2][3] The protein encoded by this gene is known to associate with HS1, a substrate of Src family tyrosine kinases. It also interacts with the product of PKD2 gene, mutations in which are associated with autosomal-dominant pol...
https://www.wikidoc.org/index.php/HAX1
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wikidoc
HBA1
HBA1 Hemoglobin, alpha 1, also known as HBA1, is a human gene encoding the hemoglobin protein. "The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) codin...
HBA1 Associate Editor(s)-in-Chief: Henry A. Hoff Hemoglobin, alpha 1, also known as HBA1, is a human gene encoding the hemoglobin protein. "The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3...
https://www.wikidoc.org/index.php/HBA1
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wikidoc
HCN1
HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 is a protein that in humans is encoded by the HCN1 gene. # Function Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, contribute to spontaneous rhythmic activity in both heart and brain. # Tissue distri...
HCN1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 is a protein that in humans is encoded by the HCN1 gene.[1][2][3][4] # Function Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, contribute to spontaneous rhythmic activity in both heart and brain.[4] ...
https://www.wikidoc.org/index.php/HCN1
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wikidoc
HEPA
HEPA # Overview A high efficiency particulate air or HEPA (Template:IPAEng) filter is a type of high-efficiency air filter. # Function HEPA filters can remove at least 99.97% of airborne particles 0.3 micrometers (µm) in diameter. Particles of this size are the most difficult to filter and are thus considered the mos...
HEPA Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview A high efficiency particulate air or HEPA[1] (Template:IPAEng) filter is a type of high-efficiency air filter. # Function HEPA filters can remove at least 99.97% of airborne particles 0.3 micrometers (µm) in diameter. Particles of this size are the m...
https://www.wikidoc.org/index.php/HEPA
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wikidoc
hERG
hERG hERG (the human Ether-à-go-go-Related Gene) is a gene (KCNH2) that codes for a protein known as Kv11.1, the alpha subunit of a potassium ion channel. This ion channel (sometimes simply denoted as 'hERG') is best known for its contribution to the electrical activity of the heart: the hERG channel mediates the repo...
hERG hERG (the human Ether-à-go-go-Related Gene) is a gene (KCNH2) that codes for a protein known as Kv11.1, the alpha subunit of a potassium ion channel. This ion channel (sometimes simply denoted as 'hERG') is best known for its contribution to the electrical activity of the heart: the hERG channel mediates the rep...
https://www.wikidoc.org/index.php/HERG
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wikidoc
HES1
HES1 Transcription factor HES1 (hairy and enhancer of split-1) is a protein that is encoded by the Hes1 gene, and is the mammalian homolog of the hairy gene in Drosophila. HES1 is one of the seven members of the Hes gene family (HES1-7). Hes genes code nuclear proteins that suppress transcription. This protein belongs ...
HES1 Transcription factor HES1 (hairy and enhancer of split-1) is a protein that is encoded by the Hes1 gene, and is the mammalian homolog of the hairy gene in Drosophila.[1][2] HES1 is one of the seven members of the Hes gene family (HES1-7). Hes genes code nuclear proteins that suppress transcription.[3] This protei...
https://www.wikidoc.org/index.php/HES1
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wikidoc
HEXA
HEXA Hexosaminidase A (alpha polypeptide), also known as HEXA, is an enzyme that in humans is encoded by the HEXA gene, located on the 15th chromosome. Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules containing terminal N-acetyl hexosamines. ...
HEXA Hexosaminidase A (alpha polypeptide), also known as HEXA, is an enzyme that in humans is encoded by the HEXA gene, located on the 15th chromosome.[1][2] Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules containing terminal N-acetyl hexosam...
https://www.wikidoc.org/index.php/HEXA
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wikidoc
HEXB
HEXB Beta-hexosaminidase subunit beta is an enzyme that in humans is encoded by the HEXB gene. Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing termina...
HEXB Beta-hexosaminidase subunit beta is an enzyme that in humans is encoded by the HEXB gene.[1][2][3] Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containi...
https://www.wikidoc.org/index.php/HEXB
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wikidoc
HEY2
HEY2 Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) also known as cardiovascular helix-loop-helix factor 1 (CHF1) is a protein that in humans is encoded by the HEY2 gene. # Function CHF1 is a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcr...
HEY2 Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) also known as cardiovascular helix-loop-helix factor 1 (CHF1) is a protein that in humans is encoded by the HEY2 gene.[1][2] # Function CHF1 is a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type ...
https://www.wikidoc.org/index.php/HEY2
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wikidoc
HHEX
HHEX Hematopoietically-expressed homeobox protein HHEX is a protein that in humans is encoded by the HHEX gene. This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may ...
HHEX Hematopoietically-expressed homeobox protein HHEX is a protein that in humans is encoded by the HHEX gene.[1][2][3] This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this pr...
https://www.wikidoc.org/index.php/HHEX
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wikidoc
HICS
HICS # HICS- Hospital Incident Command System # Background HICS is a comprehensive incident management system intended for use in both emergent and non-emergent situations. It provides hospitals of all sizes with tools needed to advance their emergency preparedness and response capability—both individually and as a m...
HICS Template:Wikify # HICS- Hospital Incident Command System # Background HICS[1][1] is a comprehensive incident management system intended for use in both emergent and non-emergent situations. It provides hospitals of all sizes with tools needed to advance their emergency preparedness and response capability—both ...
https://www.wikidoc.org/index.php/HICS
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wikidoc
HIRA
HIRA Protein HIRA is a protein that in humans is encoded by the HIRA gene. This gene is mapped to 22q11.21, centromeric to COMT. # Function The specific function of this protein has yet to be determined; however, it has been speculated to play a role in transcriptional regulation and/or chromatin and histone metabolis...
HIRA Protein HIRA is a protein that in humans is encoded by the HIRA gene.[1][2][3][4] This gene is mapped to 22q11.21, centromeric to COMT.[4] # Function The specific function of this protein has yet to be determined; however, it has been speculated to play a role in transcriptional regulation and/or chromatin and h...
https://www.wikidoc.org/index.php/HIRA
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wikidoc
HLTF
HLTF Helicase-like transcription factor is an enzyme that in humans is encoded by the HLTF gene. # Function This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around ...
HLTF Helicase-like transcription factor is an enzyme that in humans is encoded by the HLTF gene.[1][2] # Function This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure ...
https://www.wikidoc.org/index.php/HLTF
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wikidoc
HM13
HM13 Minor histocompatibility antigen H13 is a protein that in humans is encoded by the HM13 gene. # Function The minor histocompatibility antigen 13 is a nonamer peptide that originates from a protein encoded by the H13 gene. The peptide is generated by the cytosol by the proteasome, enters the endoplasmic reticulum ...
HM13 Minor histocompatibility antigen H13 is a protein that in humans is encoded by the HM13 gene.[1][2][3] # Function The minor histocompatibility antigen 13 is a nonamer peptide that originates from a protein encoded by the H13 gene.[4][5] The peptide is generated by the cytosol by the proteasome, enters the endopl...
https://www.wikidoc.org/index.php/HM13
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wikidoc
HPS4
HPS4 Hermansky-Pudlak syndrome 4 protein is a protein that in humans is encoded by the HPS4 gene. Hermansky-Pudlak syndrome is a disorder of organelle biogenesis in which oculocutaneous albinism, bleeding, and pulmonary fibrosis result from defects of melanosomes, platelet dense granules, and lysosomes. Mutations in th...
HPS4 Hermansky-Pudlak syndrome 4 protein is a protein that in humans is encoded by the HPS4 gene.[1][2][3] Hermansky-Pudlak syndrome is a disorder of organelle biogenesis in which oculocutaneous albinism, bleeding, and pulmonary fibrosis result from defects of melanosomes, platelet dense granules, and lysosomes. Mutat...
https://www.wikidoc.org/index.php/HPS4
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wikidoc
HPS6
HPS6 Hermansky-Pudlak syndrome 6 (HPS6) also known as ruby-eye protein homolog (Ru) is a protein that in humans is encoded by the HPS6 gene. # Function This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. HPS6 along wit...
HPS6 Hermansky-Pudlak syndrome 6 (HPS6) also known as ruby-eye protein homolog (Ru) is a protein that in humans is encoded by the HPS6 gene.[1] # Function This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes.[2] HPS6 al...
https://www.wikidoc.org/index.php/HPS6
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wikidoc
HRAS
HRAS GTPase HRas also known as transforming protein p21 is an enzyme that in humans is encoded by the HRAS gene. The HRAS gene is located on the short (p) arm of chromosome 11 at position 15.5, from base pair 522,241 to base pair 525,549. HRas is a small G protein in the Ras subfamily of the Ras superfamily of small GT...
HRAS GTPase HRas also known as transforming protein p21 is an enzyme that in humans is encoded by the HRAS gene.[1][2] The HRAS gene is located on the short (p) arm of chromosome 11 at position 15.5, from base pair 522,241 to base pair 525,549.[3] HRas is a small G protein in the Ras subfamily of the Ras superfamily o...
https://www.wikidoc.org/index.php/HRAS
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wikidoc
HSF1
HSF1 Heat shock factor 1 (HSF1) is a protein that in humans is encoded by the HSF1 gene. HSF1 is highly conserved in eukaryotes and is the primary mediator of transcriptional responses to proteotoxic stress with important roles in non-stress regulation such as development and metabolism. # Structure Human HSF1 consist...
HSF1 Heat shock factor 1 (HSF1) is a protein that in humans is encoded by the HSF1 gene.[1] HSF1 is highly conserved in eukaryotes and is the primary mediator of transcriptional responses to proteotoxic stress with important roles in non-stress regulation such as development and metabolism.[2] # Structure Human HSF1 ...
https://www.wikidoc.org/index.php/HSF1
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wikidoc
HSF2
HSF2 Heat shock factor protein 2 is a protein that in humans is encoded by the HSF2 gene. # Function HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. Heat shock transcription factors activate heat-shock response genes...
HSF2 Heat shock factor protein 2 is a protein that in humans is encoded by the HSF2 gene.[1][2] # Function HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. Heat shock transcription factors activate heat-shock respons...
https://www.wikidoc.org/index.php/HSF2
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wikidoc
Heme
Heme # Overview A heme or haem is a prosthetic group that consists of an iron atom contained in the center of a large heterocyclic organic ring called a porphyrin. Not all porphyrins contain iron, but a substantial fraction of porphyrin-containing metalloproteins have heme as their prosthetic subunit; these are known ...
Heme # Overview A heme or haem is a prosthetic group that consists of an iron atom contained in the center of a large heterocyclic organic ring called a porphyrin. Not all porphyrins contain iron, but a substantial fraction of porphyrin-containing metalloproteins have heme as their prosthetic subunit; these are known ...
https://www.wikidoc.org/index.php/Haem
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wikidoc
Hair
Hair # Overview Hair is a filamentous outgrowth of protein, found only on mammals. It projects from the epidermis, though it grows from hair follicles deep in the dermis. Although many other organisms, especially insects, show filamentous outgrowths, these are not considered "hair". So-called "hairs" (trichomes) are a...
Hair Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Hair is a filamentous outgrowth of protein, found only on mammals. It projects from the epidermis, though it grows from hair follicles deep in the dermis. Although many other organisms, especially insects, show filamentous outgrowths, these are not co...
https://www.wikidoc.org/index.php/Hair
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wikidoc
TSC1
TSC1 Tuberous sclerosis 1 (TSC1), also known as Hamartin, is a protein that in humans is encoded by the TSC1 gene. # Function TSC1 functions as a co-chaperone which inhibits the ATPase activity of the chaperone Hsp90 (heat shock protein-90) and decelerates its chaperone cycle. Tsc1 functions as a facilitator of Hsp90...
TSC1 Tuberous sclerosis 1 (TSC1), also known as Hamartin, is a protein that in humans is encoded by the TSC1 gene.[1] # Function TSC1 functions as a co-chaperone which inhibits the ATPase activity of the chaperone Hsp90 (heat shock protein-90) and decelerates its chaperone cycle. Tsc1 functions as a facilitator of H...
https://www.wikidoc.org/index.php/Hamartin
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wikidoc
Hand
Hand # Overview The hands (med./lat.: manus, pl. manūs) are the two intricate, prehensile, multi-fingered body parts normally located at the end of each arm of a human or other primate. They are the chief organs for physically manipulating the environment, using anywhere from the roughest motor skills (wielding a club...
Hand Template:Infobox Anatomy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The hands (med./lat.: manus, pl. manūs) are the two intricate, prehensile, multi-fingered body parts normally located at the end of each arm of a human or other primate. They are the chief organs for physically manipulating th...
https://www.wikidoc.org/index.php/Hand
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wikidoc
HeLa
HeLa A HeLa cell (also Hela or hela cell) is an immortal cell line used in medical research. The cell line was derived from cervical cancer cells taken from Henrietta Lacks, who died from her cancer in 1951. # George Otto Gey and Henrietta Lacks The cells were propagated by George Otto Gey without Lacks' knowledge or...
HeLa A HeLa cell (also Hela or hela cell) is an immortal cell line used in medical research. The cell line was derived from cervical cancer cells taken from Henrietta Lacks, who died from her cancer in 1951. # George Otto Gey and Henrietta Lacks The cells were propagated by George Otto Gey without Lacks' knowledge o...
https://www.wikidoc.org/index.php/HeLa
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wikidoc
Head
Head In anatomy, the head of an animal is the rostral part (from anatomical position) that usually comprises the brain, eyes, ears, nose, and mouth (all of which aid in various sensory functions, such as sight, hearing, smell, and taste). Some very simple animals may not have a head, but many bilaterally symmetric form...
Head Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] In anatomy, the head of an animal is the rostral part (from anatomical position) that usually comprises the brain, eyes, ears, nose, and mouth (all of which aid in various sensory functions, such as sight, hearing, smell, and taste). Some very simple animals may ...
https://www.wikidoc.org/index.php/Head
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wikidoc
Heat
Heat In physics, heat, symbolized by Q, is energy transferred from one body or system to another due to a difference in temperature. In thermodynamics, the quantity TdS is used as a representative measure of heat, which is the absolute temperature of an object multiplied by the differential quantity of a system's entr...
Heat Template:Pp-semi-vandalism In physics, heat, symbolized by Q, is energy transferred from one body or system to another due to a difference in temperature.[1][2] In thermodynamics, the quantity TdS is used as a representative measure of heat, which is the absolute temperature of an object multiplied by the differ...
https://www.wikidoc.org/index.php/Heat
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wikidoc
Hoof
Hoof A hoof is the tip of a toe of an ungulate mammal, strengthened by a thick horny (keratin) covering. The hoof consists of a hard or rubbery sole, and a hard wall formed by a thick nail rolled around the tip of the toe. The weight of the animal is normally borne by both the sole and the edge of the hoof wall. Hoo...
Hoof A hoof is the tip of a toe of an ungulate mammal, strengthened by a thick horny (keratin) covering. The hoof consists of a hard or rubbery sole, and a hard wall formed by a thick nail rolled around the tip of the toe. The weight of the animal is normally borne by both the sole and the edge of the hoof wall. Ho...
https://www.wikidoc.org/index.php/Hoof
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wikidoc
Hope
Hope # Overview Hope is a belief in a positive outcome related to events and circumstances in one's life. Hope implies a certain amount of despair, wanting, wishing, suffering or perseverance — i.e., believing that a better or positive outcome is possible even when there is some evidence to the contrary. Beyond the ...
Hope Template:Emotion Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Hope is a belief in a positive outcome related to events and circumstances in one's life. Hope implies a certain amount of despair, wanting, wishing, suffering or perseverance — i.e., believing that a better or positive outcome is po...
https://www.wikidoc.org/index.php/Hope
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wikidoc
Stye
Stye Synonyms and keywords: Hordeolum # Overview A stye (also known as a hordeolum) is a painful infection of the sebaceous glands at the base of the eyelashes on, inside, or under the eyelid.. The infection may be internal or external. In many cases, a hordeolum may resolve without treatment; however, the inflammatio...
Stye Template:DiseaseDisorder infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]; Faizan Sheraz, M.D. [3] Synonyms and keywords: Hordeolum # Overview A stye (also known as a hordeolum) is a painful infection of the sebaceous glands at the base ...
https://www.wikidoc.org/index.php/Hordeolum
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wikidoc
IDH1
IDH1 Isocitrate dehydrogenase 1 (NADP+), soluble is an enzyme that in humans is encoded by the IDH1 gene on chromosome 2. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which uses NAD+ as the electron acceptor and...
IDH1 Isocitrate dehydrogenase 1 (NADP+), soluble is an enzyme that in humans is encoded by the IDH1 gene on chromosome 2. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which uses NAD+ as the electron acceptor an...
https://www.wikidoc.org/index.php/IDH1
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wikidoc
IDH2
IDH2 Isocitrate dehydrogenase , mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases are enzymes that catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor...
IDH2 Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene.[1] Isocitrate dehydrogenases are enzymes that catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electro...
https://www.wikidoc.org/index.php/IDH2
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wikidoc
IGL@
IGL@ Immunoglobulin lambda locus, also known as IGL@, is a region on human chromosome 22 that contains genes for the lambda light chains of antibodies (or immunoglobulins). # Function Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglo...
IGL@ Immunoglobulin lambda locus, also known as IGL@, is a region on human chromosome 22 that contains genes for the lambda light chains of antibodies (or immunoglobulins).[1] # Function Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immun...
https://www.wikidoc.org/index.php/IGL@
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wikidoc
IKK2
IKK2 IKK-β also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene. # Function IKK-β is an enzyme that serves as a protein subunit of IκB kinase, which is a component of...
IKK2 IKK-β also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene. # Function IKK-β is an enzyme that serves as a protein subunit of IκB kinase, which is a component o...
https://www.wikidoc.org/index.php/IKK2
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wikidoc
IL1A
IL1A Interleukin 1 alpha (IL-1α) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrup...
IL1A Interleukin 1 alpha (IL-1α) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.[1][2] In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to i...
https://www.wikidoc.org/index.php/IL1A
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wikidoc
ILF2
ILF2 Interleukin enhancer-binding factor 2 is a protein that in humans is encoded by the ILF2 gene. # Function Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen ...
ILF2 Interleukin enhancer-binding factor 2 is a protein that in humans is encoded by the ILF2 gene.[1][2] # Function Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the a...
https://www.wikidoc.org/index.php/ILF2
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wikidoc
ILF3
ILF3 Interleukin enhancer-binding factor 3 is a protein that in humans is encoded by the ILF3 gene. # Function Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response elemen...
ILF3 Interleukin enhancer-binding factor 3 is a protein that in humans is encoded by the ILF3 gene.[1][2] # Function Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response...
https://www.wikidoc.org/index.php/ILF3
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wikidoc
ING4
ING4 Inhibitor of growth protein 4 is a protein that in humans is encoded by the ING4 gene. # Function The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in p...
ING4 Inhibitor of growth protein 4 is a protein that in humans is encoded by the ING4 gene.[1][2] # Function The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common mot...
https://www.wikidoc.org/index.php/ING4
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wikidoc
INTJ
INTJ INTJ (Introverted iNtuitive Thinking Judging) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, INTJs belong to the temperament of the rationals and are called Masterminds. The INTJ may also be referred to as "the scienti...
INTJ INTJ (Introverted iNtuitive Thinking Judging) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, INTJs belong to the temperament of the rationals and are called Masterminds. The INTJ may also be referred to as "the scient...
https://www.wikidoc.org/index.php/INTJ
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wikidoc
IPO5
IPO5 Importin-5 is a protein that in humans is encoded by the IPO5 gene. The protein encoded by this gene is a member of the importin beta family. # Function Nuclear transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins co...
IPO5 Importin-5 is a protein that in humans is encoded by the IPO5 gene.[1][2][3] The protein encoded by this gene is a member of the importin beta family. # Function Nuclear transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of p...
https://www.wikidoc.org/index.php/IPO5
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wikidoc
IRF3
IRF3 Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. # Function IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functio...
IRF3 Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor.[1] # Function IRF3 is a member of the interferon regulatory transcription factor (IRF) family.[1] IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several ...
https://www.wikidoc.org/index.php/IRF3
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wikidoc
IRF4
IRF4 Interferon regulatory factor 4 also known as MUM1 is a protein that in humans is encoded by the IRF4 gene, located at 6p25-p23. The MUM1 symbol is polysemous; although it is an older synonym for IRF4 (HGNC:6119), it is also the current HGNC official symbol for melanoma associated antigen (mutated) 1 (HGNC:29641; l...
IRF4 Interferon regulatory factor 4 also known as MUM1 is a protein that in humans is encoded by the IRF4 gene,[1][2][3] located at 6p25-p23. The MUM1 symbol is polysemous; although it is an older synonym for IRF4 (HGNC:6119), it is also the current HGNC official symbol for melanoma associated antigen (mutated) 1 (HGN...
https://www.wikidoc.org/index.php/IRF4
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wikidoc
IRF5
IRF5 Interferon regulatory factor 5 is a protein that in humans is encoded by the IRF5 gene. # Function IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiati...
IRF5 Interferon regulatory factor 5 is a protein that in humans is encoded by the IRF5 gene.[1] # Function IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, different...
https://www.wikidoc.org/index.php/IRF5
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wikidoc
IRF6
IRF6 Interferon regulatory factor 6 also known as IRF6 is a protein that in humans is encoded by the IRF6 gene. # Function This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly conserved N-terminal helix-turn-helix DNA-binding domain and a less conserv...
IRF6 Interferon regulatory factor 6 also known as IRF6 is a protein that in humans is encoded by the IRF6 gene.[1] # Function This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly conserved N-terminal helix-turn-helix DNA-binding domain and a less con...
https://www.wikidoc.org/index.php/IRF6
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wikidoc
IRF7
IRF7 Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors. # Function IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcript...
IRF7 Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors. # Function IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcrip...
https://www.wikidoc.org/index.php/IRF7
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wikidoc
IRF8
IRF8 Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene. IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision ...
IRF8 Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene.[1][2][3] IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the...
https://www.wikidoc.org/index.php/IRF8
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wikidoc
IRGM
IRGM Immunity-related GTPase family M protein (IRGM), also known as interferon-inducible protein 1 (IFI1), is an enzyme that in humans is IRGM gene. IRGM is a member of the interferon-inducible GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response...
IRGM Immunity-related GTPase family M protein (IRGM), also known as interferon-inducible protein 1 (IFI1), is an enzyme that in humans is IRGM gene.[1] IRGM is a member of the interferon-inducible GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in resp...
https://www.wikidoc.org/index.php/IRGM
a55c8719c6cc0afe06f4f5103cfb351198af3f3d
wikidoc
IRS1
IRS1 Insulin receptor substrate 1 (IRS-1) is a signaling adapter protein that in humans is encoded by the IRS-1 gene. It is a 131 kDa protein with amino acid sequence of 1242 residues. It contains a single pleckstrin homology (PH) domain at the N-terminus and a PTB domain ca. 40 residues downstream of this, followed by...
IRS1 Insulin receptor substrate 1 (IRS-1) is a signaling adapter protein that in humans is encoded by the IRS-1 gene.[1] It is a 131 kDa protein with amino acid sequence of 1242 residues.[2] It contains a single pleckstrin homology (PH) domain at the N-terminus and a PTB domain ca. 40 residues downstream of this, foll...
https://www.wikidoc.org/index.php/IRS-1
ab4c2e33f785a89ebd56fd83f51bdba6316e181e
wikidoc
IRS2
IRS2 Insulin receptor substrate 2 is a protein that in humans is encoded by the IRS2 gene. # Function This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse...
IRS2 Insulin receptor substrate 2 is a protein that in humans is encoded by the IRS2 gene.[1] # Function This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between div...
https://www.wikidoc.org/index.php/IRS2
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wikidoc
IRX1
IRX1 Iroquois-class homeodomain protein IRX-1, also known as Iroquois homeobox protein 1, is a protein that in humans is encoded by the IRX1 gene. All members of the Iroquois (IRO) family of proteins share two highly conserved features, encoding both a homeodomain and a characteristic IRO sequence motif. Members of thi...
IRX1 Iroquois-class homeodomain protein IRX-1, also known as Iroquois homeobox protein 1, is a protein that in humans is encoded by the IRX1 gene.[1][2] All members of the Iroquois (IRO) family of proteins share two highly conserved features, encoding both a homeodomain and a characteristic IRO sequence motif.[3] Memb...
https://www.wikidoc.org/index.php/IRX1
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wikidoc
IRX3
IRX3 Iroquois-class homeodomain protein IRX-3, also known as Iroquois homeobox protein 3, is a protein that in humans is encoded by the IRX3 gene. # Function IRX3 is a member of the Iroquois homeobox gene family and plays a role in an early step of neural development. Members of this family appear to play multiple rol...
IRX3 Iroquois-class homeodomain protein IRX-3, also known as Iroquois homeobox protein 3, is a protein that in humans is encoded by the IRX3 gene.[1] # Function IRX3 is a member of the Iroquois homeobox gene family and plays a role in an early step of neural development.[2] Members of this family appear to play multi...
https://www.wikidoc.org/index.php/IRX3
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wikidoc
ISCU
ISCU Iron-sulfur cluster assembly enzyme ISCU, mitochondrial is a protein that in humans is encoded by the ISCU gene. It encodes an iron-sulfur (Fe-S) cluster scaffold protein involved in and cluster synthesis and maturation. A deficiency of ISCU is associated with a mitochondrial myopathy with lifelong exercise into...
ISCU Iron-sulfur cluster assembly enzyme ISCU, mitochondrial is a protein that in humans is encoded by the ISCU gene.[1] It encodes an iron-sulfur (Fe-S) cluster scaffold protein involved in [2Fe-2S] and [4Fe-4S] cluster synthesis and maturation.[2][3][4][5] A deficiency of ISCU is associated with a mitochondrial myop...
https://www.wikidoc.org/index.php/ISCU
cee875a9ea6f7a0f9af472e30b4c142675558444
wikidoc
ISFJ
ISFJ ISFJ (Introverted Sensing Feeling Judging) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ISFJs belong to the Guardian temperament and are called Protectors. # Myers-Briggs Characteristics According to Myers-Briggs, ...
ISFJ ISFJ (Introverted Sensing Feeling Judging) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ISFJs belong to the Guardian temperament and are called Protectors. # Myers-Briggs Characteristics According to Myers-Briggs,...
https://www.wikidoc.org/index.php/ISFJ
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wikidoc
ISFP
ISFP ISFP (Introverted Sensing Feeling Perceiving) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ISFPs belong to the Artisan temperament and are called "Composers". # Myers-Briggs Characteristics According to Myers-Briggs,...
ISFP ISFP (Introverted Sensing Feeling Perceiving) is one of the sixteen personality types from the Myers-Briggs Type Indicator (MBTI), and the Keirsey Temperament Sorter. Referring to Keirsey, ISFPs belong to the Artisan temperament and are called "Composers". # Myers-Briggs Characteristics According to Myers-Briggs...
https://www.wikidoc.org/index.php/ISFP
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wikidoc
ISL1
ISL1 Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. # Function This gene encodes a transcription factor containing two N-terminal LIM domains and one C-terminal homeodomain. The encoded protein plays an important role in the embryogenesis of pancreatic islets of Langerhans...
ISL1 Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene.[1][2] # Function This gene encodes a transcription factor containing two N-terminal LIM domains and one C-terminal homeodomain. The encoded protein plays an important role in the embryogenesis of pancreatic islets of Lan...
https://www.wikidoc.org/index.php/ISL1
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wikidoc
ITPA
ITPA Inosine triphosphate pyrophosphatase is an enzyme that in humans is encoded by the ITPA gene, by the rdgB gene in bacteria E.coli and the HAM1 gene in yeast S. cerevisiae. Two transcript variants encoding two different isoforms have been found for this gene. Also, at least two other transcript variants have been ...
ITPA Inosine triphosphate pyrophosphatase is an enzyme that in humans is encoded by the ITPA gene,[1][2] by the rdgB gene in bacteria E.coli[3] and the HAM1 gene in yeast S. cerevisiae.[4] Two transcript variants encoding two different isoforms have been found for this gene. Also, at least two other transcript varian...
https://www.wikidoc.org/index.php/ITPA
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wikidoc
Idli
Idli The idli (IPA:Template:IPA), also romanized "idly" or "iddly", is a steamed rice cake popular throughout South India. It is made by steaming batter — traditionally made from pulses (specifically black lentils) and rice — into patties, usually two to three inches in diameter, using a mold. Most often eaten at break...
Idli The idli (IPA:Template:IPA), also romanized "idly" or "iddly", is a steamed rice cake popular throughout South India. It is made by steaming batter — traditionally made from pulses (specifically black lentils) and rice — into patties, usually two to three inches in diameter, using a mold. Most often eaten at brea...
https://www.wikidoc.org/index.php/Idli
c35b325f044c0f5a46f2681e70a0cd789bf80276
wikidoc
Inch
Inch An inch (plural: inches; symbol or abbreviation: in or, sometimes,  ″ — U+2033 - a double prime) is the name of a unit of length in a number of different systems, including English units, Imperial units, and United States customary units. Its size can vary from system to system. There are 36 inches in a yard and 1...
Inch Template:Unit of length An inch (plural: inches; symbol or abbreviation: in or, sometimes,  ″ — U+2033 - a double prime) is the name of a unit of length in a number of different systems, including English units, Imperial units, and United States customary units. Its size can vary from system to system. There are ...
https://www.wikidoc.org/index.php/Inch
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wikidoc
JAG1
JAG1 Jagged1 (JAG1) is one of five cell surface proteins (ligands) that interact with 4 receptors in the mammalian Notch signaling pathway. The Notch Signaling Pathway is a highly conserved pathway that functions to establish and regulate cell fate decisions in many organ systems. Once the JAG1-NOTCH (receptor-ligand) ...
JAG1 Jagged1 (JAG1) is one of five cell surface proteins (ligands) that interact with 4 receptors in the mammalian Notch signaling pathway. The Notch Signaling Pathway is a highly conserved pathway that functions to establish and regulate cell fate decisions in many organ systems. Once the JAG1-NOTCH (receptor-ligand)...
https://www.wikidoc.org/index.php/JAG1
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wikidoc
JAM2
JAM2 Junctional adhesion molecule B is a protein that in humans is encoded by the JAM2 gene. JAM2 has also been designated as CD322 (cluster of differentiation 322). # Function Tight junctions represent one mode of cell-to-cell adhesion in endothelial cell sheets, forming continuous seals around cells and serving as a...
JAM2 Junctional adhesion molecule B is a protein that in humans is encoded by the JAM2 gene.[1][2][3] JAM2 has also been designated as CD322 (cluster of differentiation 322). # Function Tight junctions represent one mode of cell-to-cell adhesion in endothelial cell sheets, forming continuous seals around cells and se...
https://www.wikidoc.org/index.php/JAM2
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wikidoc
JAM3
JAM3 Junctional adhesion molecule C is a protein that in humans is encoded by the JAM3 gene. # Gene This gene is located on the long arm of chromosome 11 (11q25) on the Watson strand. It is 83,077 bases in length. The encoded protein is 310 amino acids long with a predicted molecular weight of 35.02 kiloDaltons. # Fu...
JAM3 Junctional adhesion molecule C is a protein that in humans is encoded by the JAM3 gene.[1] # Gene This gene is located on the long arm of chromosome 11 (11q25) on the Watson strand. It is 83,077 bases in length. The encoded protein is 310 amino acids long with a predicted molecular weight of 35.02 kiloDaltons. ...
https://www.wikidoc.org/index.php/JAM3
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wikidoc
JP-8
JP-8 # Overview JP-8, or JP8 (for "Jet Propellant 8") is a jet fuel, specified and used widely by the US military. It is specified by MIL-DTL-83133 and British Defence Standard 91-87, and similar to commercial aviation's Jet-A. A kerosene-based fuel, JP-8 is projected to remain in use at least until 2025. It was first...
JP-8 Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview JP-8, or JP8 (for "Jet Propellant 8") is a jet fuel, specified and used widely by the US military. It is specified by MIL-DTL-83133 and British Defence Standard 91-87, and similar to commercial aviation's Jet-A. A kerosene-based fuel, JP-8 is projecte...
https://www.wikidoc.org/index.php/JP-8
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wikidoc
JPH2
JPH2 Junctophilin 2, also known as JPH2, is a protein which in humans is encoded by the JPH2 gene. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. # Function Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a com...
JPH2 Junctophilin 2, also known as JPH2, is a protein which in humans is encoded by the JPH2 gene.[1][2][3] Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. # Function Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum...
https://www.wikidoc.org/index.php/JPH2
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wikidoc
JunD
JunD Transcription factor JunD is a protein that in humans is encoded by the JUND gene. # Function The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apopt...
JunD Transcription factor JunD is a protein that in humans is encoded by the JUND gene.[1][2] # Function The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence an...
https://www.wikidoc.org/index.php/JUND
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wikidoc
KAT5
KAT5 Histone acetyltransferase KAT5 is an enzyme that in humans is encoded by the KAT5 gene. It is also commonly identified as TIP60. The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important rol...
KAT5 Histone acetyltransferase KAT5 is an enzyme that in humans is encoded by the KAT5 gene.[1][2] It is also commonly identified as TIP60. The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play import...
https://www.wikidoc.org/index.php/KAT5
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wikidoc
KLC1
KLC1 Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene. Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chain...
KLC1 Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene.[1][2][3] Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the l...
https://www.wikidoc.org/index.php/KLC1
7d693d79ab03e33aa90491205da0f6694f93b549
wikidoc
KLF1
KLF1 Krueppel-like factor 1 is a protein that in humans is encoded by the KLF1 gene. The gene for KLF1 is on the human chromosome 19 and on mouse chromosome 8. Krueppel-like factor 1 is a transcription factor that is necessary for the proper maturation of erythroid (red blood) cells. # Structure The molecule has two ...
KLF1 Krueppel-like factor 1 is a protein that in humans is encoded by the KLF1 gene. The gene for KLF1 is on the human chromosome 19 and on mouse chromosome 8. Krueppel-like factor 1 is a transcription factor that is necessary for the proper maturation of erythroid (red blood) cells. # Structure The molecule has two...
https://www.wikidoc.org/index.php/KLF1
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wikidoc
KLF2
KLF2 Krüppel-like Factor 2 (KLF2), also known as lung Krüppel-like Factor (LKLF), is a protein that in humans is encoded by the KLF2 gene on chromosome 19. It is a member of the Krüppel-like factor family of zinc finger transcription factors, and it has been implicated in a variety of biochemical processes in the human...
KLF2 Krüppel-like Factor 2 (KLF2), also known as lung Krüppel-like Factor (LKLF), is a protein that in humans is encoded by the KLF2 gene on chromosome 19.[1][2] It is a member of the Krüppel-like factor family of zinc finger transcription factors, and it has been implicated in a variety of biochemical processes in th...
https://www.wikidoc.org/index.php/KLF2
ff393ed73e2ccdec41db8d63e19aebe5703936c6
wikidoc
KLF3
KLF3 Krüppel-like factor 3 is a protein that in humans is encoded by the KLF3 gene. # Structure KLF3, originally termed Basic Krüppel-like Factor (BKLF), was the third member of the Krüppel-like factor family of zinc finger transcription factors to be discovered. Transcription factors in this family bind DNA by virtue...
KLF3 Krüppel-like factor 3 is a protein that in humans is encoded by the KLF3 gene. # Structure KLF3, originally termed Basic Krüppel-like Factor (BKLF), was the third member of the Krüppel-like factor family of zinc finger transcription factors to be discovered.[1] Transcription factors in this family bind DNA by vi...
https://www.wikidoc.org/index.php/KLF3
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wikidoc
KLF4
KLF4 Kruppel-like factor 4 (KLF4; gut-enriched Krüppel-like factor or GKLF) is a zinc-finger transcription factor, and it was first identified in 1996. KLF4 is a member of the KLF family of transcription factors, which belongs to the relatively large family of SP1-like transcription factors. KLF4 is involved in the reg...
KLF4 Kruppel-like factor 4 (KLF4; gut-enriched Krüppel-like factor or GKLF) is a zinc-finger transcription factor, and it was first identified in 1996.[1] KLF4 is a member of the KLF family of transcription factors, which belongs to the relatively large family of SP1-like transcription factors.[2][3][4] KLF4 is involv...
https://www.wikidoc.org/index.php/KLF4
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wikidoc
KLF9
KLF9 Krueppel-like factor 9 is a protein that in humans is encoded by the KLF9 gene. Previously known as Basic Transcription Element Binding Protein 1 (BTEB Protein 1), Klf9 is part of the Sp1 C2H2-type zinc finger family of transcription factors. Several previous studies showed Klf9-related regulation of animal devel...
KLF9 Krueppel-like factor 9 is a protein that in humans is encoded by the KLF9 gene.[1][2] Previously known as Basic Transcription Element Binding Protein 1 (BTEB Protein 1), Klf9 is part of the Sp1 C2H2-type zinc finger family of transcription factors. Several previous studies showed Klf9-related regulation of anima...
https://www.wikidoc.org/index.php/KLF9
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wikidoc
KLK4
KLK4 Kallikrein-related peptidase 4 is a protein which in humans is encoded by the KLK4 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease ...
KLK4 Kallikrein-related peptidase 4 is a protein which in humans is encoded by the KLK4 gene.[1][2][3] Kallikreins are a subgroup of serine proteases having diverse physiological functions.[4] Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and o...
https://www.wikidoc.org/index.php/KLK-4
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wikidoc
KLK7
KLK7 Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene. KLK7 was initially purified from the epidermis and characterised as stratum corneum chymotryptic enzyme (SCCE). It was later identified as the seventh member of the human kallikrein family, which includes fifteen...
KLK7 Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene.[1][2][3][4] KLK7 was initially purified from the epidermis and characterised as stratum corneum chymotryptic enzyme (SCCE).[5] It was later identified as the seventh member of the human kallikrein family, which ...
https://www.wikidoc.org/index.php/KLK7
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wikidoc
KLK9
KLK9 Kallikrein-related peptidase 9 also known as KLK9 is an enzyme which in humans is encoded by the KLK9 gene. # Function KLK9 belongs to the kallikrein subgroup of serine proteases, which have diverse physiologic functions in many tissues. KLK9 is primarily expressed in thymus, testis, spinal cord, cerebellum, trac...
KLK9 Kallikrein-related peptidase 9 also known as KLK9 is an enzyme which in humans is encoded by the KLK9 gene.[1] # Function KLK9 belongs to the kallikrein subgroup of serine proteases, which have diverse physiologic functions in many tissues.[2][3][4] KLK9 is primarily expressed in thymus, testis, spinal cord, cer...
https://www.wikidoc.org/index.php/KLK9
04fa552f46029ca54b5df5f830b67143463dbb90
wikidoc
KNL1
KNL1 KNL1 (kinetochore scaffold 1, aka CASC5) is a protein that is encoded by the KNL1 gene in humans. # Function KNL1 is part of the outer kinetochore. It is a part of KMN network of proteins together with MIS12, and NDC80. KNL1 is involved in microtubule attachment to chromosome centromeres and in the activation of ...
KNL1 KNL1 (kinetochore scaffold 1, aka CASC5) is a protein that is encoded by the KNL1 gene in humans.[1][2][3][4] # Function KNL1 is part of the outer kinetochore. It is a part of KMN network of proteins together with MIS12, and NDC80.[5] KNL1 is involved in microtubule attachment to chromosome centromeres and in th...
https://www.wikidoc.org/index.php/KNL1
bd1abae5b15bd18459d4fd0aee91b0560c97252d
wikidoc
KRAS
KRAS KRAS ( K-ras or Ki-ras) is a gene that acts as an on/off switch in cell signalling. When it functions normally, it controls cell proliferation. When it is mutated, negative signalling is disrupted. Thus, cells can continuously proliferate, and often develop into cancer. It is called KRAS because it was first ident...
KRAS KRAS ( K-ras or Ki-ras) is a gene that acts as an on/off switch in cell signalling. When it functions normally, it controls cell proliferation. When it is mutated, negative signalling is disrupted. Thus, cells can continuously proliferate, and often develop into cancer. It is called KRAS because it was first iden...
https://www.wikidoc.org/index.php/KRAS
74ae681ffe10cfb07b782b20dbe6e5fe896831a9
wikidoc
KTN1
KTN1 Kinectin is a protein that in humans is encoded by the KTN1 gene. # Function Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysos...
KTN1 Kinectin is a protein that in humans is encoded by the KTN1 gene.[1][2] # Function Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment o...
https://www.wikidoc.org/index.php/KTN1
a986849d29947f16e1383032845949ca437094ef
wikidoc
Kava
Kava Kava (Piper methysticum) (Piper Latin for "pepper", methysticum Greek for "intoxicating") is an ancient crop of the western Pacific. Other names for kava include Template:Okinaawa (Hawaii), 'ava (Samoa), yaqona (Fiji), and sakau (Pohnpei). The word kava is used to refer both to the plant and the beverage produced...
Kava Kava (Piper methysticum) (Piper Latin for "pepper", methysticum Greek for "intoxicating") is an ancient crop of the western Pacific. Other names for kava include Template:Okinaawa (Hawaii), 'ava (Samoa), yaqona (Fiji), and sakau (Pohnpei). The word kava is used to refer both to the plant and the beverage produce...
https://www.wikidoc.org/index.php/Kava
8e71032e07abdc528d74ffac5aedede726d1b75e
wikidoc
Khat
Khat Khat (Catha edulis, family Celastraceae, Ge'ez ጫት č̣āt; Arabic: قات; Somali: Jaad; IPA: Template:IPA), and also known as qat, gat, chat, and miraa), is a flowering plant native to tropical East Africa and the Arabian Peninsula. Believed to have originated in Ethiopia, it is a shrub or small tree growing to 5–8 m ...
Khat Template:Disputed Khat (Catha edulis, family Celastraceae, Ge'ez ጫት č̣āt; Arabic: قات; Somali: Jaad; IPA: Template:IPA), and also known as qat, gat, chat, and miraa), is a flowering plant native to tropical East Africa and the Arabian Peninsula. Believed to have originated in Ethiopia, it is a shrub or small tre...
https://www.wikidoc.org/index.php/Khat
9472ede4c5c080d166c8133caa24eb0f93ecb943
wikidoc
Knee
Knee # Overview In human anatomy, the knee is the lower extremity joint connecting the femur and the tibia. Since in humans the knee supports nearly the entire weight of the body, it is the joint most vulnerable both to acute injury and to the development of osteoarthritis. # Function of the knee The knee functions a...
Knee Template:Infobox Anatomy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview In human anatomy, the knee is the lower extremity joint connecting the femur and the tibia. Since in humans the knee supports nearly the entire weight of the body, it is the joint most vulnerable both to acute injury and to th...
https://www.wikidoc.org/index.php/Knee
8e277edf2a4271564ff33e5ab35dbb35abbb90ae
wikidoc
Kt/V
Kt/V In medicine, Kt/V is a number used to quantify hemodialysis and peritoneal dialysis treatment adequacy. - K - dialyzer clearance of urea - t - dialysis time - V - patient's total body water In the context of hemodialysis, Kt/V is a bonafide dimensionless number that can be derived using the Buckingham π theorem. ...
Kt/V In medicine, Kt/V is a number used to quantify hemodialysis and peritoneal dialysis treatment adequacy. - K - dialyzer clearance of urea - t - dialysis time - V - patient's total body water In the context of hemodialysis, Kt/V is a bonafide dimensionless number that can be derived using the Buckingham π theorem. ...
https://www.wikidoc.org/index.php/Kt/V
c0ad3349ce06d62063fb1d66aa6750d581ed0a18
wikidoc
Ku70
Ku70 Ku70 is a protein that, in humans, is encoded by the XRCC6 gene. # Function Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes...
Ku70 Ku70 is a protein that, in humans, is encoded by the XRCC6 gene.[1][2] # Function Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which u...
https://www.wikidoc.org/index.php/Ku70
d05f7a3cc65d83dcf7bdfa1bfe9bf989b6f575ab
wikidoc
Ku80
Ku80 Ku80 is a protein that, in humans, is encoded by the XRCC5 gene. Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ p...
Ku80 Ku80 is a protein that, in humans, is encoded by the XRCC5 gene.[1] Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NH...
https://www.wikidoc.org/index.php/Ku80
ab980b7a9dc02fc5cfa7f3b42b7ae20ff4d1b04b
wikidoc
LAG3
LAG3 Lymphocyte-activation gene 3, also known as LAG-3, is a protein which in humans is encoded by the LAG3 gene. LAG3, which was discovered in 1990 and was designated CD223 (cluster of differentiation 223) after the Seventh Human Leucocyte Differentiation Antigen Workshop in 2000, is a cell surface molecule with diver...
LAG3 Lymphocyte-activation gene 3, also known as LAG-3, is a protein which in humans is encoded by the LAG3 gene.[1] LAG3, which was discovered in 1990[2] and was designated CD223 (cluster of differentiation 223) after the Seventh Human Leucocyte Differentiation Antigen Workshop in 2000,[3] is a cell surface molecule ...
https://www.wikidoc.org/index.php/LAG3
ef1d96bbd60bead381ba80f3c39a7adab221610d
wikidoc
LCHN
LCHN LCHN is a protein that in humans is encoded by the KIAA1147 gene (NCBI Gene ID 57189) located on chromosome 7. It is likely part of the tripartite DENN domain family of proteins that often function as Rab-GEFs to regulate vesicular trafficking. Both the mRNA and protein have been shown to be upregulated following ...
LCHN LCHN is a protein that in humans is encoded by the KIAA1147 gene (NCBI Gene ID 57189) located on chromosome 7.[1] It is likely part of the tripartite DENN domain family of proteins that often function as Rab-GEFs[2][3] to regulate vesicular trafficking.[2] Both the mRNA and protein have been shown to be upregulat...
https://www.wikidoc.org/index.php/LCHN
da59672fbd60de66fd80ed93dc48524aa812c196
wikidoc
LDB3
LDB3 LIM domain binding 3 (LDB3), also known as Z-band alternatively spliced PDZ-motif (ZASP), is a protein which in humans is encoded by the LDB3 gene. ZASP belongs to the Enigma subfamily of proteins and stabilizes the sarcomere (the basic units of muscles) during contraction, through interactions with actin in cardi...
LDB3 LIM domain binding 3 (LDB3), also known as Z-band alternatively spliced PDZ-motif (ZASP), is a protein which in humans is encoded by the LDB3 gene.[1][2] ZASP belongs to the Enigma subfamily of proteins and stabilizes the sarcomere (the basic units of muscles) during contraction, through interactions with actin i...
https://www.wikidoc.org/index.php/LDB3
697704d9d81a988b56ddc5b0ec826f55498306cb
wikidoc
LFNG
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, also known as LFNG and Lunatic Fringe, is a human gene. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, addin...
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, also known as LFNG and Lunatic Fringe,[1][2] is a human gene.[3] This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransfer...
https://www.wikidoc.org/index.php/LFNG
4cb38b643d00cb132c167ea295391a9cd0f06dca
wikidoc
LGI1
LGI1 Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. It may be a metastasis suppressor. # Function The leucine-rich glioma inactivated -1 gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic seg...
LGI1 Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene.[1] It may be a metastasis suppressor. # Function The leucine-rich glioma inactivated -1 gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic...
https://www.wikidoc.org/index.php/LGI1
ce73854f33b4d3f6b7f9dae4b8bad1dc130f9d5b
wikidoc
LGP2
LGP2 Probable ATP-dependent RNA helicase DHX58 also known as RIG-I-like receptor 3 (RLR-3) or RIG-I-like receptor LGP2 (RLR) is a RIG-I-like receptor dsRNA helicase enzyme that in humans is encoded by the DHX58 gene. The protein encoded by the gene DHX58 is known as LGP2 (Laboratory of Genetics and Physiology 2). # S...
LGP2 Probable ATP-dependent RNA helicase DHX58 also known as RIG-I-like receptor 3 (RLR-3) or RIG-I-like receptor LGP2 (RLR) is a RIG-I-like receptor dsRNA helicase enzyme that in humans is encoded by the DHX58 gene.[1][2] The protein encoded by the gene DHX58 is known as LGP2 (Laboratory of Genetics and Physiology 2...
https://www.wikidoc.org/index.php/LGP2
81d56521cca8e3a859e354e2d9e2a723c9b6e248
wikidoc
LGR5
LGR5 Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) also known as G-protein coupled receptor 49 (GPR49) or G-protein coupled receptor 67 (GPR67) is a protein that in humans is encoded by the LGR5 gene. It is a member of GPCR class A receptor proteins. R-spondin proteins are the biological ligands of...
LGR5 Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) also known as G-protein coupled receptor 49 (GPR49) or G-protein coupled receptor 67 (GPR67) is a protein that in humans is encoded by the LGR5 gene.[1][2] It is a member of GPCR class A receptor proteins. R-spondin proteins are the biological lig...
https://www.wikidoc.org/index.php/LGR5
9bddef8a9a22ffe7d77cdad6c07c76205606d6f6
wikidoc
LHX1
LHX1 LIM homeobox 1 is a protein that in humans is encoded by the LHX1 gene. This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for control of differentiation and development of neural an...
LHX1 LIM homeobox 1 is a protein that in humans is encoded by the LHX1 gene.[1] This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for control of differentiation and development of neura...
https://www.wikidoc.org/index.php/LHX1
0a3b78794b08076e3973e5cb7ff6394cb8580841
wikidoc
LHX3
LHX3 LIM/homeobox protein Lhx3 is a protein that in humans is encoded by the LHX3 gene. # Function LHX3 encodes a protein of a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary developmen...
LHX3 LIM/homeobox protein Lhx3 is a protein that in humans is encoded by the LHX3 gene.[1][2][3] # Function LHX3 encodes a protein of a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary ...
https://www.wikidoc.org/index.php/LHX3
afd13482a2fa546290153b8a9b90065863a5c375
wikidoc
LIG1
LIG1 DNA ligase 1 is an enzyme that in humans is encoded by the LIG1 gene. DNA ligases are important tools for DNA replication and repair in living organisms. There are two families of DNA ligases, ATP-dependent DNA ligases and NAD+ dependent DNA ligases. Dependence upon ATP or NAD+ is conferred in the ligase-adenylate...
LIG1 DNA ligase 1 is an enzyme that in humans is encoded by the LIG1 gene. DNA ligases are important tools for DNA replication and repair in living organisms. There are two families of DNA ligases, ATP-dependent DNA ligases and NAD+ dependent DNA ligases. Dependence upon ATP or NAD+ is conferred in the ligase-adenylat...
https://www.wikidoc.org/index.php/LIG1
f1c23e228810c04ba54ef689f40de899033c7922
wikidoc
LIG3
LIG3 DNA ligase 3 is an enzyme that, in humans, is encoded by the LIG3 gene. The human LIG3 gene encodes ATP-dependent DNA ligases that seal interruptions in the phosphodiester backbone of duplex DNA. There are three families of ATP-dependent DNA ligases in eukaryotes. These enzymes utilize the same three step reaction...
LIG3 DNA ligase 3 is an enzyme that, in humans, is encoded by the LIG3 gene.[1][2] The human LIG3 gene encodes ATP-dependent DNA ligases that seal interruptions in the phosphodiester backbone of duplex DNA. There are three families of ATP-dependent DNA ligases in eukaryotes.[3] These enzymes utilize the same three ste...
https://www.wikidoc.org/index.php/LIG3