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wikidoc
Mean
Mean In statistics, mean has two related meanings: - the arithmetic mean (and is distinguished from the geometric mean or harmonic mean). - the expected value of a random variable, which is also called the population mean. It is sometimes stated that the 'mean' means average. This is incorrect as there are different ty...
Mean Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] In statistics, mean has two related meanings: - the arithmetic mean (and is distinguished from the geometric mean or harmonic mean). - the expected value of a random variable, which is also called the population mean. It is sometimes stated that the 'mean' means ...
https://www.wikidoc.org/index.php/Mean
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Mesh
Mesh Mesh products are similar to fabric or a web in that it has many connected or woven strands. In clothing, a mesh is often defined as a loosely woven fabric that has a large number of closely-spaced holes, frequently used for modern sports jerseys and other clothing. # Types of mesh - A plastic mesh is extruded, o...
Mesh Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Mesh products are similar to fabric or a web in that it has many connected or woven strands. In clothing, a mesh is often defined as a loosely woven fabric that has a large number of closely-spaced holes, frequently used for modern sports jerseys and other clothi...
https://www.wikidoc.org/index.php/Mesh
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wikidoc
Mile
Mile A mile is a unit of length, usually used to measure distance, in a number of different systems, including Imperial units, United States customary units and Norwegian/Swedish mil. Its size can vary from system to system, but in each is between one and ten kilometers. In contemporary English contexts, mile most comm...
Mile Template:Unit of length A mile is a unit of length, usually used to measure distance, in a number of different systems, including Imperial units, United States customary units and Norwegian/Swedish mil. Its size can vary from system to system, but in each is between one and ten kilometers. In contemporary English...
https://www.wikidoc.org/index.php/Mile
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wikidoc
Milk
Milk # Overview Milk is an opaque white liquid produced by the mammary glands of female mammals (including monotremes). Mammary glands are highly specialized sweat glands. The female ability to produce milk is one of the defining characteristics of mammals. It provides the primary source of nutrition for newborns befo...
Milk # Overview Milk is an opaque white liquid produced by the mammary glands of female mammals (including monotremes). Mammary glands are highly specialized sweat glands. The female ability to produce milk is one of the defining characteristics of mammals. It provides the primary source of nutrition for newborns befo...
https://www.wikidoc.org/index.php/Milk
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wikidoc
Torr
Torr The torr (symbol: Torr) is a non-SI unit of pressure defined as 1/760 of an atmosphere. It was named after Evangelista Torricelli, an Italian physicist and mathematician who discovered the principle of the barometer in 1644. # History Torricelli attracted considerable attention when he demonstrated the first merc...
Torr Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] The torr (symbol: Torr) is a non-SI unit of pressure defined as 1/760 of an atmosphere. It was named after Evangelista Torricelli, an Italian physicist and mathematician who discovered the principle of the barometer in 1644.[1] # History Torricelli attracted con...
https://www.wikidoc.org/index.php/Millimeters_of_mercury
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wikidoc
Mite
Mite Mites, along with ticks, belong to the subclass Acarina (also known as Acari) and the class Arachnida. Mites are among the most diverse and successful of all the invertebrate groups. They have exploited an incredible array of habitats, and because of their small size (most are microscopic) most go totally unnotice...
Mite Mites, along with ticks, belong to the subclass Acarina (also known as Acari) and the class Arachnida. Mites are among the most diverse and successful of all the invertebrate groups. They have exploited an incredible array of habitats, and because of their small size (most are microscopic) most go totally unnotic...
https://www.wikidoc.org/index.php/Mite
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wikidoc
Noni
Noni Morinda citrifolia, commonly known as Great morinda, Indian mulberry, Beach mulberry, Tahitian Noni, or since recently: Noni (from Hawaiian), Nono (in Tahitian), Mengkudu (from Malay), Nonu (in Tongan), and Ach (in Hindi), is a shrub or small tree in the family Rubiaceae. Morinda citrifolia is native to Southeast...
Noni Morinda citrifolia, commonly known as Great morinda, Indian mulberry, Beach mulberry, Tahitian Noni, or since recently: Noni (from Hawaiian), Nono (in Tahitian), Mengkudu (from Malay), Nonu (in Tongan), and Ach (in Hindi), is a shrub or small tree in the family Rubiaceae. Morinda citrifolia is native to Southeas...
https://www.wikidoc.org/index.php/Morinda_citrifolia
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wikidoc
Muon
Muon The muon (from the letter mu (μ)--used to represent it) is an elementary particle with negative electric charge and a spin of 1/2. It has a mean lifetime of 2.2μs, longer than any other unstable lepton, meson, or baryon except for the neutron. Together with the electron, the tau, and the neutrinos, it is classif...
Muon Template:Infobox Particle The muon (from the letter mu (μ)--used to represent it) is an elementary particle with negative electric charge and a spin of 1/2. It has a mean lifetime of 2.2μs, longer than any other unstable lepton, meson, or baryon except for the neutron. Together with the electron, the tau, and t...
https://www.wikidoc.org/index.php/Muon
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wikidoc
MyoD
MyoD MyoD is a protein that plays a major role in regulating muscle differentiation. MyoD, which was discovered in the laboratory of Harold M. Weintraub, belongs to a family of proteins known as myogenic regulatory factors (MRFs). These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic di...
MyoD MyoD is a protein that plays a major role in regulating muscle differentiation. MyoD, which was discovered in the laboratory of Harold M. Weintraub,[1] belongs to a family of proteins known as myogenic regulatory factors (MRFs).[2] These bHLH (basic helix loop helix) transcription factors act sequentially in myog...
https://www.wikidoc.org/index.php/MyoD
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wikidoc
NAB2
NAB2 NGFI-A-binding protein 2 also known as EGR-1-binding protein 2 or melanoma-associated delayed early response protein (MADER) is a protein that in humans is encoded by the NAB2 gene. # Function This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress or ac...
NAB2 NGFI-A-binding protein 2 also known as EGR-1-binding protein 2 or melanoma-associated delayed early response protein (MADER) is a protein that in humans is encoded by the NAB2 gene.[1][2][3] # Function This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to rep...
https://www.wikidoc.org/index.php/NAB2
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NANS
NANS Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene. This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acety...
NANS Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene.[1][2] This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of ...
https://www.wikidoc.org/index.php/NANS
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NCDN
NCDN Neurochondrin (also known as its murine homologue, Norbin) is a protein that in humans is encoded by the NCDN gene. This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein norbin that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be ...
NCDN Neurochondrin (also known as its murine homologue, Norbin) is a protein that in humans is encoded by the NCDN gene.[1][2] This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein norbin that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and ...
https://www.wikidoc.org/index.php/NCDN
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wikidoc
NCK1
NCK1 Cytoplasmic protein NCK1 is a protein that in humans is encoded by the NCK1 gene. # Gene The Nck (non-catalytic region of tyrosine kinase adaptor protein 1) belongs to the adaptor family of proteins. The nck gene was initially isolated from a human melanoma cDNA library using a monoclonal antibody produced agains...
NCK1 Cytoplasmic protein NCK1 is a protein that in humans is encoded by the NCK1 gene.[1][2] # Gene The Nck (non-catalytic region of tyrosine kinase adaptor protein 1) belongs to the adaptor family of proteins. The nck gene was initially isolated from a human melanoma cDNA library using a monoclonal antibody produced...
https://www.wikidoc.org/index.php/NCK1
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wikidoc
NEK6
NEK6 Serine/threonine-protein kinase Nek6 is an enzyme that in humans is encoded by the NEK6 gene. # Function The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homologous t...
NEK6 Serine/threonine-protein kinase Nek6 is an enzyme that in humans is encoded by the NEK6 gene.[1][2] # Function The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homol...
https://www.wikidoc.org/index.php/NEK6
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NEU1
NEU1 Sialidase 1 (lysosomal sialidase), also known as NEU1 is a mammalian lysosomal neuraminidase enzyme which in humans is encoded by the NEU1 gene. # Function The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipi...
NEU1 Sialidase 1 (lysosomal sialidase), also known as NEU1 is a mammalian lysosomal neuraminidase enzyme which in humans is encoded by the NEU1 gene.[1][2] # Function The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and gl...
https://www.wikidoc.org/index.php/NEU1
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wikidoc
NFYA
NFYA Nuclear transcription factor Y subunit alpha is a protein that in humans is encoded by the NFYA gene. # Function The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit ...
NFYA Nuclear transcription factor Y subunit alpha is a protein that in humans is encoded by the NFYA gene.[1][2] # Function The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. S...
https://www.wikidoc.org/index.php/NFYA
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wikidoc
NFYC
NFYC Nuclear transcription factor Y subunit gamma is a protein that in humans is encoded by the NFYC gene. # Function The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a vari...
NFYC Nuclear transcription factor Y subunit gamma is a protein that in humans is encoded by the NFYC gene.[1][2][3] # Function The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions...
https://www.wikidoc.org/index.php/NFYC
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wikidoc
NME4
NME4 Non-metastatic cells 4, protein expressed in, also known as NME4, is a protein which in humans is encoded by the NME4 gene. # Function The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside an...
NME4 Non-metastatic cells 4, protein expressed in, also known as NME4, is a protein which in humans is encoded by the NME4 gene.[1][2] # Function The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleo...
https://www.wikidoc.org/index.php/NME4
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wikidoc
NME8
NME8 Thioredoxin domain-containing protein 3 (TXNDC3), also known as spermatid-specific thioredoxin-2 (Sptrx-2), is a protein that in humans is encoded by the NME8 gene (also known as the TXNDC3 gene) on chromosome 7. # Function This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nuc...
NME8 Thioredoxin domain-containing protein 3 (TXNDC3), also known as spermatid-specific thioredoxin-2 (Sptrx-2), is a protein that in humans is encoded by the NME8 gene (also known as the TXNDC3 gene) on chromosome 7.[1][2] # Function This gene encodes a protein with an N-terminal thioredoxin domain and three C-termi...
https://www.wikidoc.org/index.php/NME8
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NOL1
NOL1 Putative ribosomal RNA methyltransferase NOP2 is an enzyme that in humans is encoded by the NOP2 gene. The protein encoded by this gene is a nucleolar antigen expressed in proliferating cells. It is not detectable in non-proliferating normal tissue but is detectable in many human tumors. Overexpression of p120 lea...
NOL1 Putative ribosomal RNA methyltransferase NOP2 is an enzyme that in humans is encoded by the NOP2 gene.[1][2] The protein encoded by this gene is a nucleolar antigen expressed in proliferating cells. It is not detectable in non-proliferating normal tissue but is detectable in many human tumors.[3] Overexpression o...
https://www.wikidoc.org/index.php/NOL1
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wikidoc
NOM1
NOM1 Nucleolar protein with MIF4G domain 1 is a protein that in humans is encoded by the NOM1 gene. Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box ...
NOM1 Nucleolar protein with MIF4G domain 1 is a protein that in humans is encoded by the NOM1 gene.[1] Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD ...
https://www.wikidoc.org/index.php/NOM1
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wikidoc
NOS1
NOS1 Nitric oxide synthase 1 (neuronal), also known as NOS1, is an enzyme that in humans is encoded by the NOS1 gene. # Function Nitric oxide synthases (EC 1.14.13.39) (NOSs) are a family of synthases that catalyze the production of nitric oxide (NO) from L-arginine. NO is a chemical messenger with diverse functions t...
NOS1 Nitric oxide synthase 1 (neuronal), also known as NOS1, is an enzyme that in humans is encoded by the NOS1 gene.[1][2] # Function Nitric oxide synthases (EC 1.14.13.39) (NOSs) are a family of synthases that catalyze the production of nitric oxide (NO) from L-arginine. NO is a chemical messenger with diverse func...
https://www.wikidoc.org/index.php/NOS1
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wikidoc
NOX2
NOX2 NADPH oxidase 2 (Nox2), also known as cytochrome b(558) subunit beta or Cytochrome b-245 heavy chain, is a protein that in humans is encoded by the NOX2 gene (also called CYBB gene). The protein is a super-oxide generating enzyme which forms reactive oxygen species (ROS). # Function Nox2, or Cytochrome b (-245) i...
NOX2 NADPH oxidase 2 (Nox2), also known as cytochrome b(558) subunit beta or Cytochrome b-245 heavy chain, is a protein that in humans is encoded by the NOX2 gene (also called CYBB gene).[1] The protein is a super-oxide generating enzyme which forms reactive oxygen species (ROS). # Function Nox2, or Cytochrome b (-24...
https://www.wikidoc.org/index.php/NOX2
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wikidoc
NOX4
NOX4 NADPH oxidase 4 is an enzyme that in humans is encoded by the NOX4 gene, and is a member of the NOX family of NADPH oxidases. # Function Oxygen sensing is essential for homeostasis in all aerobic organisms. A phagocyte-type oxidase, similar to that responsible for the production of large amounts of reactive oxyge...
NOX4 NADPH oxidase 4 is an enzyme that in humans is encoded by the NOX4 gene, and is a member of the NOX family of NADPH oxidases.[1] # Function Oxygen sensing is essential for homeostasis in all aerobic organisms. A phagocyte-type oxidase, similar to that responsible for the production of large amounts of reactive o...
https://www.wikidoc.org/index.php/NOX4
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wikidoc
NPC1
NPC1 Niemann-Pick disease, type C1 (NPC1) is a disease of a membrane protein that mediates intracellular cholesterol trafficking in mammals. In humans the protein is encoded by the NPC1 gene (chromosome location 18q11). # Function NPC1 was identified as the gene that when mutated, results in Niemann-Pick disease, type...
NPC1 Niemann-Pick disease, type C1 (NPC1) is a disease of a membrane protein that mediates intracellular cholesterol trafficking in mammals. In humans the protein is encoded by the NPC1 gene (chromosome location 18q11).[1][2] # Function NPC1 was identified as the gene that when mutated, results in Niemann-Pick diseas...
https://www.wikidoc.org/index.php/NPC1
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wikidoc
NPM1
NPM1 Nucleophosmin (NPM), also known as nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. # Function NPM1 is associated with nucleolar ribonucleoprotein structures and binds single-stranded and double-stranded nucleic acids, but it binds preferentially G-quadruplex for...
NPM1 Nucleophosmin (NPM), also known as nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene.[1][2] # Function NPM1 is associated with nucleolar ribonucleoprotein structures and binds single-stranded and double-stranded nucleic acids, but it binds preferentially G-quadrup...
https://www.wikidoc.org/index.php/NPM1
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wikidoc
NPR1
NPR1 Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), also known as NPR1, is an atrial natriuretic peptide receptor. In humans it is encoded by the NPR1 gene. # Function NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic...
NPR1 Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), also known as NPR1, is an atrial natriuretic peptide receptor. In humans it is encoded by the NPR1 gene. # Function NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriureti...
https://www.wikidoc.org/index.php/NPR1
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wikidoc
NPTN
NPTN Neuroplastin is a protein that in humans is encoded by the NPTN gene. Neuroplastin is a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. The alpha and beta transcripts show differential localization within...
NPTN Neuroplastin is a protein that in humans is encoded by the NPTN gene.[1][2][3] Neuroplastin is a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. The alpha and beta transcripts show differential localizat...
https://www.wikidoc.org/index.php/NPTN
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wikidoc
NRAP
NRAP Nebulin-related-anchoring protein (N-RAP) is a protein that in humans is encoded by the NRAP gene. N-RAP is a muscle-specific isoform belonging to the nebulin family of proteins. This family is composed of 5 members: N-RAP, nebulin, nebulette, LASP-1 and LASP-2. N-RAP is involved in both myofibrillar myogenesis du...
NRAP Nebulin-related-anchoring protein (N-RAP) is a protein that in humans is encoded by the NRAP gene. N-RAP is a muscle-specific isoform belonging to the nebulin family of proteins. This family is composed of 5 members: N-RAP, nebulin, nebulette, LASP-1 and LASP-2. N-RAP is involved in both myofibrillar myogenesis d...
https://www.wikidoc.org/index.php/NRAP
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wikidoc
NRF1
NRF1 Nuclear respiratory factor 1, also known as Nrf1, Nrf-1, NRF1 and NRF-1, encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondria...
NRF1 Nuclear respiratory factor 1, also known as Nrf1, Nrf-1, NRF1 and NRF-1, encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondri...
https://www.wikidoc.org/index.php/NRF1
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NT5C
NT5C 5', 3'-nucleotidase, cytosolic, also known as 5'(3')-deoxyribonucleotidase, cytosolic type (cdN) or deoxy-5'-nucleotidase 1 (dNT-1), is an enzyme that in humans is encoded by the NT5C gene on chromosome 17. This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) ...
NT5C 5', 3'-nucleotidase, cytosolic, also known as 5'(3')-deoxyribonucleotidase, cytosolic type (cdN) or deoxy-5'-nucleotidase 1 (dNT-1), is an enzyme that in humans is encoded by the NT5C gene on chromosome 17.[1][2][3] This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotid...
https://www.wikidoc.org/index.php/NT5C
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NT5M
NT5M 5',3'-nucleotidase, mitochondrial, also known as 5'(3')-deoxyribonucleotidase, mitochondrial (mdN) or deoxy-5'-nucleotidase 2 (dNT-2), is an enzyme that in humans is encoded by the NT5M gene. This gene encodes a 5' nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5'- and 2'...
NT5M 5',3'-nucleotidase, mitochondrial, also known as 5'(3')-deoxyribonucleotidase, mitochondrial (mdN) or deoxy-5'-nucleotidase 2 (dNT-2), is an enzyme that in humans is encoded by the NT5M gene. This gene encodes a 5' nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5'- and 2...
https://www.wikidoc.org/index.php/NT5M
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wikidoc
NUB1
NUB1 NEDD8 ultimate buster 1 is a protein that in humans is encoded by the NUB1 gene. # Function NUB1 interacts with and negatively regulates NEDD8 (MIM 603171), a ubiquitin-like protein that covalently conjugates to cullin (see MIM 603134) family members. # Interactions NUB1 has been shown to interact with NEDD8, UB...
NUB1 NEDD8 ultimate buster 1 is a protein that in humans is encoded by the NUB1 gene.[1][2][3] # Function NUB1 interacts with and negatively regulates NEDD8 (MIM 603171), a ubiquitin-like protein that covalently conjugates to cullin (see MIM 603134) family members.[supplied by OMIM][3] # Interactions NUB1 has been s...
https://www.wikidoc.org/index.php/NUB1
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wikidoc
NXF1
NXF1 Nuclear RNA export factor 1, also known as NXF1 or TAP, is a protein which in humans is encoded by the NXF1 gene. # Function This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (L...
NXF1 Nuclear RNA export factor 1, also known as NXF1 or TAP, is a protein which in humans is encoded by the NXF1 gene.[1][2] # Function This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich rep...
https://www.wikidoc.org/index.php/NXF1
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wikidoc
Neck
Neck # Overview The neck is the part of the body on many limbed vertebrates that distinguishes the head from the torso or trunk. # Anatomy of the human neck ## Bony anatomy: The cervical spine The cervical portion of the human spine comprises seven bony segments, typically referred to as C-1 to C-7, with cartilagino...
Neck Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The neck is the part of the body on many limbed vertebrates that distinguishes the head from the torso or trunk. # Anatomy of the human neck ## Bony anatomy: The cervical spine The cervical portion of the human spine comprises seven bony segments, t...
https://www.wikidoc.org/index.php/Neck
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wikidoc
Neon
Neon Neon (Template:PronEng) is the chemical element that has the symbol Ne and atomic number 10. A very common element in the universe, it is rare on Earth. A colorless, inert noble gas under standard conditions, neon gives a distinct reddish glow when used in vacuum discharge tubes and neon lamps. It is commercially ...
Neon Template:Infobox neon Neon (Template:PronEng) is the chemical element that has the symbol Ne and atomic number 10. A very common element in the universe, it is rare on Earth. A colorless, inert noble gas under standard conditions, neon gives a distinct reddish glow when used in vacuum discharge tubes and neon lam...
https://www.wikidoc.org/index.php/Neon
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Nose
Nose # Overview Anatomically, a nose is a protuberance in vertebrates that houses the nostrils, or nares, which admit and expel air for respiration in conjunction with the mouth. In most humans, it also houses the nosehairs, which catch airborne particles and prevent them from reaching the lungs. Within and behind th...
Nose # Overview Anatomically, a nose is a protuberance in vertebrates that houses the nostrils, or nares, which admit and expel air for respiration in conjunction with the mouth. In most humans, it also houses the nosehairs, which catch airborne particles and prevent them from reaching the lungs. Within and behind th...
https://www.wikidoc.org/index.php/Nose
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wikidoc
Nuke
Nuke The word nuke, as a verb or a noun, can refer to multiple things: - A colloquialism for a nuclear weapon, or the use of one, or the equivalent destruction of the use of one (as an analogy) - A colloquialism for a nuclear power plant - A member of the United States Navy trained to operate a naval reactor (i.e. nucl...
Nuke The word nuke, as a verb or a noun, can refer to multiple things: - A colloquialism for a nuclear weapon, or the use of one, or the equivalent destruction of the use of one (as an analogy) - A colloquialism for a nuclear power plant - A member of the United States Navy trained to operate a naval reactor (i.e. nuc...
https://www.wikidoc.org/index.php/Nuke
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wikidoc
OCA2
OCA2 P protein, also known as melanocyte-specific transporter protein or pink-eyed dilution protein homolog, is a protein that in humans is encoded by the oculocutaneous albinism II (OCA2) gene. The P protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine - a ...
OCA2 P protein, also known as melanocyte-specific transporter protein or pink-eyed dilution protein homolog, is a protein that in humans is encoded by the oculocutaneous albinism II (OCA2) gene.[1] The P protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine ...
https://www.wikidoc.org/index.php/OCA2
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wikidoc
OCLC
OCLC # Overview OCLC Online Computer Library Center, Inc. is a "nonprofit, membership, computer library service and research organization dedicated to the public purpose of furthering access to the world's information and reducing information costs", according to its website. It was founded in 1967 as the Ohio College...
OCLC # Overview OCLC Online Computer Library Center, Inc. is a "nonprofit, membership, computer library service and research organization dedicated to the public purpose of furthering access to the world's information and reducing information costs", according to its website. It was founded in 1967 as the Ohio College...
https://www.wikidoc.org/index.php/OCLC
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wikidoc
OCRL
OCRL Inositol polyphosphate 5-phosphatase OCRL-1 (INPP5F), also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans. This gene encodes a phosphatase enzyme involved in actin polymerization, and is found in the trans-Golgi network. Mutation in thi...
OCRL Inositol polyphosphate 5-phosphatase OCRL-1 (INPP5F), also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans.[1] This gene encodes a phosphatase enzyme involved in actin polymerization, and is found in the trans-Golgi network.[1] Mutation...
https://www.wikidoc.org/index.php/OCRL
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wikidoc
OGDH
OGDH Alpha-ketoglutarate dehydrogenase also known as 2-oxoglutarate dehydrogenase E1 component, mitochondrial is an enzyme that in humans is encoded by the OGDH gene. # Structure ## Gene The OGDH gene is located on the 7th chromosome, with the specific location being 7p14-p13. There are 26 exons located within the ge...
OGDH Alpha-ketoglutarate dehydrogenase also known as 2-oxoglutarate dehydrogenase E1 component, mitochondrial is an enzyme that in humans is encoded by the OGDH gene.[1][2][3] # Structure ## Gene The OGDH gene is located on the 7th chromosome, with the specific location being 7p14-p13. There are 26 exons located wit...
https://www.wikidoc.org/index.php/OGDH
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wikidoc
OGFr
OGFr Opioid growth factor receptor, also known as OGFr or the ζ-opioid receptor, is a protein which in humans is encoded by the OGFR gene. The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as -enkephalin. The endogenous ligand is thus a known opioid peptide, and OGFr was original...
OGFr Opioid growth factor receptor, also known as OGFr or the ζ-opioid receptor, is a protein which in humans is encoded by the OGFR gene.[1][2] The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. The endogenous ligand is thus a known opioid peptide, and OG...
https://www.wikidoc.org/index.php/OGFr
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wikidoc
OLR1
OLR1 Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a protein that in humans is encoded by the OLR1 gene. LOX-1 is the main receptor for oxidized LDL on endothelial cells, macrophages, smooth muscle cells, and other cell types. But minimally ...
OLR1 Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a protein that in humans is encoded by the OLR1 gene.[1][2] LOX-1 is the main receptor for oxidized LDL on endothelial cells, macrophages, smooth muscle cells,[3] and other cell types.[4] B...
https://www.wikidoc.org/index.php/OLR1
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wikidoc
OMA1
OMA1 Metalloendopeptidase OMA1, mitochondrial is an enzyme that in humans is encoded by the OMA1 gene. As a metalloprotease, this protein is a substantial component of the quality control system in the inner membrane of mitochondria. Being activated by enzyme Bax and Bak, mitochondrial protease OMA1 promotes cytochrome...
OMA1 Metalloendopeptidase OMA1, mitochondrial is an enzyme that in humans is encoded by the OMA1 gene.[1][2] As a metalloprotease, this protein is a substantial component of the quality control system in the inner membrane of mitochondria. Being activated by enzyme Bax and Bak, mitochondrial protease OMA1 promotes cyt...
https://www.wikidoc.org/index.php/OMA1
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wikidoc
OMIM
OMIM # Overview The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome and provides references for further research and tools for genomic analysis of a catalogued gene. # Version...
OMIM Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome and provides references for further research and tools f...
https://www.wikidoc.org/index.php/OMIM
f08e19c07bead9027e09df6b5339edf8ecd9dc28
wikidoc
OPN5
OPN5 Neuropsin is a protein that in humans is encoded by the OPN5 gene. It is a photoreceptor protein sensitive to ultraviolet (UV) light. The OPN5 gene was discovered in mouse and human genomes and its mRNA expression was also found in neural tissues. Neuropsin is bistable at 0 °C and activates a UV-sensitive, heterot...
OPN5 Neuropsin is a protein that in humans is encoded by the OPN5 gene.[1][2][3] It is a photoreceptor protein sensitive to ultraviolet (UV) light. The OPN5 gene was discovered in mouse and human genomes and its mRNA expression was also found in neural tissues. Neuropsin is bistable at 0 °C and activates a UV-sensitiv...
https://www.wikidoc.org/index.php/OPN5
6f1ca27d96e7b5a5012fe6f2bf9190c1ee577a61
wikidoc
ORC6
ORC6 Origin recognition complex subunit 6 is a protein that in humans is encoded by the ORC6 (ORC6L) gene. # Background The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC ...
ORC6 Origin recognition complex subunit 6 is a protein that in humans is encoded by the ORC6 (ORC6L) gene.[1][2] # Background The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated th...
https://www.wikidoc.org/index.php/ORC6
408f197b62fb5783ea91b3138f66d79c282d81f7
wikidoc
OSBP
OSBP Oxysterol-binding protein 1 is a protein that in humans is encoded by the OSBP gene. # Function Oxysterol-binding protein (OSBP) is an intracellular protein that was identified as a cytosolic 25-hydroxycholesterol-binding protein. OSBP is a lipid transfer protein that controls cholesterol/PI4P exchange at ER-Golg...
OSBP Oxysterol-binding protein 1 is a protein that in humans is encoded by the OSBP gene.[1] # Function Oxysterol-binding protein (OSBP) is an intracellular protein that was identified as a cytosolic 25-hydroxycholesterol-binding protein.[2] OSBP is a lipid transfer protein that controls cholesterol/PI4P exchange at ...
https://www.wikidoc.org/index.php/OSBP
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wikidoc
OSR1
OSR1 Protein odd-skipped-related 1 is a transcription factor that in humans is encoded by the OSR1 gene. The OSR1 and OSR2 transcription factors participate in the normal development of body parts such as the kidney. Protein odd-skipped related 1 is a zinc-finger transcription factor that, in humans, is encoded by the ...
OSR1 Protein odd-skipped-related 1 is a transcription factor that in humans is encoded by the OSR1 gene.[1][2][3] The OSR1 and OSR2 transcription factors participate in the normal development of body parts such as the kidney.[4] Protein odd-skipped related 1 is a zinc-finger transcription factor that, in humans, is en...
https://www.wikidoc.org/index.php/OSR1
ba616a5f1401eb20dce567c3e01055070f14c5bf
wikidoc
Odor
Odor # Overview An odor or odour (see spelling differences) is a volatilized chemical compound, generally at a very low concentration, which humans and other animals perceive by the sense of olfaction. Odors are also called smells, which can refer to both pleasant and unpleasant odors. The terms fragrance, scent, o...
Odor # Overview An odor or odour (see spelling differences) is a volatilized chemical compound, generally at a very low concentration, which humans and other animals perceive by the sense of olfaction. Odors are also called smells, which can refer to both pleasant and unpleasant odors. The terms fragrance, scent, o...
https://www.wikidoc.org/index.php/Odor
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wikidoc
Oklo
Oklo Oklo is a region near the town of Franceville, in the Haut-Ogooué province of the Central African state of Gabon. The discovery in September 1972 of several natural nuclear fission reactors in the uranium mines situated there has fired the imagination and aroused the curiosity of scientists. # History Gabon was a...
Oklo Oklo is a region near the town of Franceville, in the Haut-Ogooué province of the Central African state of Gabon. The discovery in September 1972 of several natural nuclear fission reactors in the uranium mines situated there has fired the imagination and aroused the curiosity of scientists. # History Gabon was ...
https://www.wikidoc.org/index.php/Oklo
f8fcf5936b39176e6b224a9d1f07f6c758eefbc7
wikidoc
Okra
Okra Okra (American English: Template:IPA, British English Template:IPA), also known as lady's finger, bhindi and gumbo, is a flowering plant valued for its edible green fruits. Its scientific name is Abelmoschus esculentus. The species is an annual or perennial, growing to 2.5 m tall. The leaves are 10–20 cm long and ...
Okra Okra (American English: Template:IPA, British English Template:IPA), also known as lady's finger[1], bhindi and gumbo, is a flowering plant valued for its edible green fruits. Its scientific name is Abelmoschus esculentus. The species is an annual or perennial, growing to 2.5 m tall. The leaves are 10–20 cm long ...
https://www.wikidoc.org/index.php/Okra
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wikidoc
Olea
Olea # Overview Olea (/ˈoʊliːə/) is a genus of about 40 species in the family Oleaceae, native to warm temperate and tropical regions of southern Europe, Africa, southern Asia and Australasia. They are evergreen trees and shrubs, with small, opposite, entire leaves. The fruit is a drupe. Leaves of Olea contain Tricho ...
Olea Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Olea (/[invalid input: 'icon']ˈoʊliːə/)[2] is a genus of about 40 species in the family Oleaceae, native to warm temperate and tropical regions of southern Europe, Africa, southern Asia and Australasia. They are evergreen trees and shrubs, with small,...
https://www.wikidoc.org/index.php/Olea
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wikidoc
Opal
Opal Opal is a mineraloid gel which is deposited at a relatively low temperature and may occur in the fissures of almost any kind of rock, being most commonly found with limonite, sandstone, rhyolite, and basalt. The water content is usually between three and ten percent, but can be as high as 20%. Opal ranges from cle...
Opal Template:Alternateuses Template:Infobox mineral Opal is a mineraloid gel which is deposited at a relatively low temperature and may occur in the fissures of almost any kind of rock, being most commonly found with limonite, sandstone, rhyolite, and basalt. The water content is usually between three and ten percent...
https://www.wikidoc.org/index.php/Opal
def4a42f50faaad8ae2168e91d1bca3508bf1cd4
wikidoc
Osha
Osha Osha (Ligusticum porteri) is a perennial herb used for its medicinal properties. Osha grows in parts of the Rocky Mountains especially in the North American Southwest. L. porteri (Osha) root or L. wallichii (Ligusticum) root can be steeped in ethanol (whisky, vodka, etc.) for at least a month. The resulting tinctu...
Osha Osha (Ligusticum porteri) is a perennial herb used for its medicinal properties. Osha grows in parts of the Rocky Mountains especially in the North American Southwest. L. porteri (Osha) root or L. wallichii (Ligusticum) root can be steeped in ethanol (whisky, vodka, etc.) for at least a month. The resulting tinct...
https://www.wikidoc.org/index.php/Osha
abcdad4282fce824ba64d0a833cfadae951c7351
wikidoc
P4HB
P4HB Protein disulfide-isomerase, also known as the beta-subunit of prolyl 4-hydroxylase (P4HB), is an enzyme that in humans encoded by the P4HB gene. The human P4HB gene is localized in chromosome 17q25. Unlike other prolyl 4-hydroxylase family proteins, this protein is multifunctional and acts as an oxidoreductase fo...
P4HB Protein disulfide-isomerase, also known as the beta-subunit of prolyl 4-hydroxylase (P4HB), is an enzyme that in humans encoded by the P4HB gene. The human P4HB gene is localized in chromosome 17q25.[1][2][3][4] Unlike other prolyl 4-hydroxylase family proteins, this protein is multifunctional and acts as an oxid...
https://www.wikidoc.org/index.php/P4HB
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wikidoc
PAG1
PAG1 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 is a protein that in humans is encoded by the PAG1 gene. The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell acti...
PAG1 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 is a protein that in humans is encoded by the PAG1 gene.[1][2] The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T ce...
https://www.wikidoc.org/index.php/PAG1
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wikidoc
PAK1
PAK1 Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene. PAK1 is one of six members of the PAK family of serine/threonine kinases which are broadly divided into group I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK6 and PAK5/7). The PAKs are evolutionarily conserved. PAK1 loca...
PAK1 Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene.[1][2] PAK1 is one of six members of the PAK family of serine/threonine kinases which are broadly divided into group I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK6 and PAK5/7).[3][4] The PAKs are evolutionarily conserv...
https://www.wikidoc.org/index.php/PAK1
bae2e8a1cfd86974e6f4decea64451250800de3d
wikidoc
PAK2
PAK2 Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene. PAK2 is one of three members of Group I PAK family of serine/threonine kinases. The PAKs are evolutionary conserved. PAK2 and its cleaved fragment localize in both the cytoplasmic or nuclear compartments. PAK2 signaling ...
PAK2 Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene.[1][2] PAK2 is one of three members of Group I PAK family of serine/threonine kinases.[3][4] The PAKs are evolutionary conserved.[5] PAK2 and its cleaved fragment localize in both the cytoplasmic or nuclear compartments....
https://www.wikidoc.org/index.php/PAK2
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wikidoc
PAK3
PAK3 PAK3 (p21-activated kinase 2, beta-PAK) is one of three members of Group I PAK family of evolutionary conserved serine/threonine kinases. PAK3 is preferentially expressed in neuronal cells and involved in synapse formation and plasticity and mental retardation. # Discovery PAK3 was initially cloned from a murine...
PAK3 PAK3 (p21-activated kinase 2, beta-PAK) is one of three members of Group I PAK family of evolutionary conserved serine/threonine kinases.[1][2][3] PAK3 is preferentially expressed in neuronal cells [4][5] and involved in synapse formation and plasticity and mental retardation.[6][7] # Discovery PAK3 was initiall...
https://www.wikidoc.org/index.php/PAK3
a8a769508dc937bf73ac27612a7a4b5d5eb7c18a
wikidoc
PAK4
PAK4 Serine/threonine-protein kinase PAK 4 is an enzyme that in humans is encoded by the PAK4 gene. PAK4 is one of six members of the PAK family of serine/threonine kinases which are divided into group I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK6 and PAK5/7). PAK4 localizes in sub-cellular domains of the cytoplasm ...
PAK4 Serine/threonine-protein kinase PAK 4 is an enzyme that in humans is encoded by the PAK4 gene.[1][2][3] PAK4 is one of six members of the PAK family of serine/threonine kinases which are divided into group I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK6 and PAK5/7).[4][5] PAK4 localizes in sub-cellular domains o...
https://www.wikidoc.org/index.php/PAK4
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wikidoc
PAK5
PAK5 Serine/threonine-protein kinase PAK 5 is an enzyme that in humans is encoded by the PAK5 gene. The PAK5 enzyme is one of three members of Group II PAK family of serine/threonine kinases, and evolutionary conserved across species. # Discovery The PAK5 was initially cloned as a brain-specific kinase with a predomin...
PAK5 Serine/threonine-protein kinase PAK 5 is an enzyme that in humans is encoded by the PAK5 gene.[1][2][3] The PAK5 enzyme is one of three members of Group II PAK family of serine/threonine kinases,[4][5] and evolutionary conserved across species.[6] # Discovery The PAK5 was initially cloned as a brain-specific kin...
https://www.wikidoc.org/index.php/PAK5
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wikidoc
PAK6
PAK6 Serine/threonine-protein kinase PAK 6 is an enzyme that in humans is encoded by the PAK6 gene. PAK6 belongs to the Group II PAK family members. Like other family members, PAK6 is also evolutionary conserved across species. # Discovery The PAK6 was originally cloned as an androgen receptor interacting kinase which...
PAK6 Serine/threonine-protein kinase PAK 6 is an enzyme that in humans is encoded by the PAK6 gene.[1][2] PAK6 belongs to the Group II PAK family members.[3] Like other family members, PAK6 is also evolutionary conserved across species.[4] # Discovery The PAK6 was originally cloned as an androgen receptor interacting...
https://www.wikidoc.org/index.php/PAK6
5741a0d4c16926b92ed55144a4565b6d9694a2ec
wikidoc
PAPB
PAPB Polyaminopropyl biguanide (PAPB) is a preservative used in cleaning solutions for contact lenses. U.S. Pat. No. 4,758,595 to Ogunbiyi et al. discloses a contact-lens solution containing a Polyaminopropyl biguanide (PAPB), also known as polyhexamethylene biguanide (PHMB) or Polyhexanide, in combination with a borat...
PAPB Polyaminopropyl biguanide (PAPB) is a preservative used in cleaning solutions for contact lenses. U.S. Pat. No. 4,758,595 to Ogunbiyi et al. discloses a contact-lens solution containing a Polyaminopropyl biguanide (PAPB), also known as polyhexamethylene biguanide (PHMB) or Polyhexanide, in combination with a bora...
https://www.wikidoc.org/index.php/PAPB
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wikidoc
PARL
PARL Presenilins-associated rhomboid-like protein, mitochondrial also known as mitochondrial intramembrane cleaving protease PARL is an inner mitochondrial membrane protein that in humans is encoded by the PARL gene on chromosome 3. It is a member of the rhomboid family of intramembrane serine proteases. This protein i...
PARL Presenilins-associated rhomboid-like protein, mitochondrial also known as mitochondrial intramembrane cleaving protease PARL is an inner mitochondrial membrane protein that in humans is encoded by the PARL gene on chromosome 3.[1] It is a member of the rhomboid family of intramembrane serine proteases.[2] This pr...
https://www.wikidoc.org/index.php/PARL
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wikidoc
PAWR
PAWR PRKC, apoptosis, WT1, regulator, also known as PAWR or Prostate apoptosis response-4 (Par-4), is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells. # Function The tumor suppressor WT1 represses and activates transcription. The protein encoded by thi...
PAWR PRKC, apoptosis, WT1, regulator, also known as PAWR or Prostate apoptosis response-4 (Par-4), is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells. # Function The tumor suppressor WT1 represses and activates transcription. The protein encoded by th...
https://www.wikidoc.org/index.php/PAWR
2ff0e2dfa3ab304f2ec5b883e2c5fc898714a707
wikidoc
PAX2
PAX2 Paired box gene 2, also known as PAX2 is a protein which in humans is encoded by the PAX2 gene. # Function The Pax Genes, or Paired-Box Containing Genes, play important roles in the development and proliferation of multiple cell lines, development of organs, and development and organization of the central nervous...
PAX2 Paired box gene 2, also known as PAX2 is a protein which in humans is encoded by the PAX2 gene.[1][2] # Function The Pax Genes, or Paired-Box Containing Genes, play important roles in the development and proliferation of multiple cell lines, development of organs, and development and organization of the central ...
https://www.wikidoc.org/index.php/PAX2
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wikidoc
PAX3
PAX3 The PAX3 (paired box gene 3) gene encodes a member of the paired box or PAX family of transcription factors. The PAX family consists of nine human (PAX1-PAX9) and nine mouse (Pax1-Pax9) members arranged into four subfamilies. Human PAX3 and mouse Pax3 are present in a subfamily along with the highly homologous hum...
PAX3 The PAX3 (paired box gene 3) gene encodes a member of the paired box or PAX family of transcription factors.[1] The PAX family consists of nine human (PAX1-PAX9) and nine mouse (Pax1-Pax9) members arranged into four subfamilies. Human PAX3 and mouse Pax3 are present in a subfamily along with the highly homologous...
https://www.wikidoc.org/index.php/PAX3
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wikidoc
PAX5
PAX5 Paired box protein Pax-5 is a protein that in humans is encoded by the PAX5 gene. # Function The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are i...
PAX5 Paired box protein Pax-5 is a protein that in humans is encoded by the PAX5 gene.[1][2][3] # Function The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX prot...
https://www.wikidoc.org/index.php/PAX5
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wikidoc
PAX6
PAX6 Paired box protein Pax-6, also known as aniridia type II protein (AN2) or oculorhombin, is a protein that in humans is encoded by the PAX6 gene. Pax6 is a transcription factor present during embryonic development. The encoded protein contains two different binding sites that are known to bind DNA and function as r...
PAX6 Paired box protein Pax-6, also known as aniridia type II protein (AN2) or oculorhombin, is a protein that in humans is encoded by the PAX6 gene.[1] Pax6 is a transcription factor present during embryonic development. The encoded protein contains two different binding sites that are known to bind DNA and function ...
https://www.wikidoc.org/index.php/PAX6
f5cbd6df79180e0b952b61157703c7e7287b25f0
wikidoc
PAX7
PAX7 Paired box protein Pax-7 is a protein that in humans is encoded by the PAX7 gene. # Function Pax-7 plays a role in neural crest development and gastrulation, and it is an important factor in the expression of neural crest markers such as Slug, Sox9, Sox10 and HNK-1. PAX7 is expressed in the palatal shelf of the m...
PAX7 Paired box protein Pax-7 is a protein that in humans is encoded by the PAX7 gene.[1][2][3] # Function Pax-7 plays a role in neural crest development and gastrulation, and it is an important factor in the expression of neural crest markers such as Slug, Sox9, Sox10 and HNK-1.[4] PAX7 is expressed in the palatal s...
https://www.wikidoc.org/index.php/PAX7
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wikidoc
PAX8
PAX8 Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene. # Function This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type home...
PAX8 Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene.[1] # Function This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type ...
https://www.wikidoc.org/index.php/PAX8
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wikidoc
PAX9
PAX9 Paired box gene 9, also known as PAX9, is a protein which in humans is encoded by the PAX9 gene. It is also found in other mammals. # Expression and function This gene is a member of the paired box (PAX) family of transcription factors. During mouse embryogenesis Pax9 expression starts from embryonic day 8.5 an...
PAX9 Paired box gene 9, also known as PAX9, is a protein which in humans is encoded by the PAX9 gene.[1][2] It is also found in other mammals.[3] # Expression and function This gene is a member of the paired box (PAX) family of transcription factors. During mouse embryogenesis Pax9 expression starts from embryonic ...
https://www.wikidoc.org/index.php/PAX9
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wikidoc
PCA3
PCA3 Prostate cancer antigen 3 (PCA3, also referred to as DD3) is a gene that expresses a non-coding RNA. PCA3 is only expressed in human prostate tissue, and the gene is highly overexpressed in prostate cancer. Because of its restricted expression profile, the PCA3 RNA is useful as a tumor marker. # Use as biomarker ...
PCA3 Prostate cancer antigen 3 (PCA3, also referred to as DD3) is a gene that expresses a non-coding RNA. PCA3 is only expressed in human prostate tissue, and the gene is highly overexpressed in prostate cancer.[1][2] Because of its restricted expression profile, the PCA3 RNA is useful as a tumor marker.[3] # Use as ...
https://www.wikidoc.org/index.php/PCA3
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wikidoc
PCAF
PCAF P300/CBP-associated factor (PCAF), also known as K(lysine) acetyltransferase 2B (KAT2B), is a human gene and transcriptional coactivator associated with p53. # Structure Several domains of PCAF can act independently or in unison to enable its functions. PCAF has separate acetyltransferase and E3 ubiquitin ligase ...
PCAF P300/CBP-associated factor (PCAF), also known as K(lysine) acetyltransferase 2B (KAT2B), is a human gene and transcriptional coactivator associated with p53. # Structure Several domains of PCAF can act independently or in unison to enable its functions. PCAF has separate acetyltransferase and E3 ubiquitin ligase...
https://www.wikidoc.org/index.php/PCAF
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wikidoc
PCK1
PCK1 Phosphoenolpyruvate carboxykinase 1 (soluble), also known as PCK1, is an enzyme which in humans is encoded by the PCK1 gene. # Function This enzyme is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruva...
PCK1 Phosphoenolpyruvate carboxykinase 1 (soluble), also known as PCK1, is an enzyme which in humans is encoded by the PCK1 gene.[1][2] # Function This enzyme is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoeno...
https://www.wikidoc.org/index.php/PCK1
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wikidoc
PCK2
PCK2 Phosphoenolpyruvate carboxykinase 2, mitochondrial (PCK2, PEPCK-M), is an isozyme of phosphoenolpyruvate carboxykinase (PCK, PEPCK) that in humans is encoded by the PCK2 gene on chromosome 14. This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) ...
PCK2 Phosphoenolpyruvate carboxykinase 2, mitochondrial (PCK2, PEPCK-M), is an isozyme of phosphoenolpyruvate carboxykinase (PCK, PEPCK) that in humans is encoded by the PCK2 gene on chromosome 14. This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP)...
https://www.wikidoc.org/index.php/PCK2
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wikidoc
PCLO
PCLO Protein piccolo is a protein that in humans is encoded by the PCLO gene. # Function Synaptic vesicles dock and fuse in the active zone of the plasma membrane at chemical synapses. The presynaptic cytoskeletal matrix (PCM), which is associated with the active zone and is situated between synaptic vesicles, is thou...
PCLO Protein piccolo is a protein that in humans is encoded by the PCLO gene.[1][2][3] # Function Synaptic vesicles dock and fuse in the active zone of the plasma membrane at chemical synapses. The presynaptic cytoskeletal matrix (PCM), which is associated with the active zone and is situated between synaptic vesicle...
https://www.wikidoc.org/index.php/PCLO
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wikidoc
PCNA
PCNA # Overview Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase delta in eukaryotic cells. It achieves this processivity by encircling the DNA, thus creating a topological link to the genome. It is an example of a DNA clamp. The protein e...
PCNA Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase delta in eukaryotic cells. It achieves this processivity by encircling the DNA, thus creating a topological link to the gen...
https://www.wikidoc.org/index.php/PCNA
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wikidoc
PCNT
PCNT Pericentrin (kendrin), also known as PCNT and pericentrin-B (PCNTB), is a protein which in humans is encoded by the PCNT gene on chromosome 21. This protein localizes to the centrosome and recruits proteins to the pericentriolar matrix (PCM) to ensure proper centrosome and mitotic spindle formation, and thus, unin...
PCNT Pericentrin (kendrin), also known as PCNT and pericentrin-B (PCNTB), is a protein which in humans is encoded by the PCNT gene on chromosome 21.[1][2][3][4] This protein localizes to the centrosome and recruits proteins to the pericentriolar matrix (PCM) to ensure proper centrosome and mitotic spindle formation, a...
https://www.wikidoc.org/index.php/PCNT
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wikidoc
PDE1
PDE1 PDE1 (phosphodiesterase1) is a phosphodiesterase enzyme also known as calcium- and calmodulin-dependent phosphodiesterase. It is one of the 11 families of phosphodiesterase (PDE1-PDE11). PDE1 has three subtypes, PDE1A, PDE1B and PDE1C which divide further into various isoforms. The various isoforms exhibit differe...
PDE1 PDE1 (phosphodiesterase1) is a phosphodiesterase enzyme also known as calcium- and calmodulin-dependent phosphodiesterase. It is one of the 11 families of phosphodiesterase (PDE1-PDE11). PDE1 has three subtypes, PDE1A, PDE1B and PDE1C which divide further into various isoforms. The various isoforms exhibit differ...
https://www.wikidoc.org/index.php/PDE1
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wikidoc
PDK2
PDK2 Pyruvate dehydrogenase kinase isoform 2 (PDK2) also known as pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial is an enzyme that in humans is encoded by the PDK2 gene. PDK2 is an isozyme of pyruvate dehydrogenase kinase. # Structure The protein encoded by the PDK2 gene has two sites, an active site...
PDK2 Pyruvate dehydrogenase kinase isoform 2 (PDK2) also known as pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial is an enzyme that in humans is encoded by the PDK2 gene.[1][2] PDK2 is an isozyme of pyruvate dehydrogenase kinase. # Structure The protein encoded by the PDK2 gene has two sites, an acti...
https://www.wikidoc.org/index.php/PDK2
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wikidoc
PDK3
PDK3 Pyruvate dehydrogenase lipoamide kinase isozyme 3, mitochondrial is an enzyme that in humans is encoded by the PDK3 gene. It codes for an isozyme of pyruvate dehydrogenase kinase.The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion o...
PDK3 Pyruvate dehydrogenase lipoamide kinase isozyme 3, mitochondrial is an enzyme that in humans is encoded by the PDK3 gene.[1] [2] It codes for an isozyme of pyruvate dehydrogenase kinase.The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conve...
https://www.wikidoc.org/index.php/PDK3
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wikidoc
PDK4
PDK4 Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene. It codes for an isozyme of pyruvate dehydrogenase kinase. This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This ...
PDK4 Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene.[1][2] It codes for an isozyme of pyruvate dehydrogenase kinase. This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain...
https://www.wikidoc.org/index.php/PDK4
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wikidoc
PDPN
PDPN Podoplanin is a protein that in humans is encoded by the "PDPN" gene. # Structure and function Podoplanin is a mucin-type protein with a mass of 36- to 43-kDa. It is relatively well conserved between species, with homologues in humans, mice, rats, dogs and hamsters. This gene encodes a type-I, integral membrane, ...
PDPN Podoplanin is a protein that in humans is encoded by the "PDPN" gene.[1][2][3] # Structure and function Podoplanin is a mucin-type protein with a mass of 36- to 43-kDa. It is relatively well conserved between species, with homologues in humans, mice, rats, dogs and hamsters.[4] This gene encodes a type-I, integr...
https://www.wikidoc.org/index.php/PDPN
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wikidoc
PDPR
PDPR Pyruvate dehydrogenase phosphatase regulatory subunit is a protein that in humans is encoded by the PDPR gene. # Structure The complete cDNA of PDPR, which contains 2885 base pairs, has an open reading frame of 2634 nucleotides encoding a putative presequence of 31 amino acid residues and a mature protein of 847....
PDPR Pyruvate dehydrogenase phosphatase regulatory subunit is a protein that in humans is encoded by the PDPR gene.[1] # Structure The complete cDNA of PDPR, which contains 2885 base pairs, has an open reading frame of 2634 nucleotides encoding a putative presequence of 31 amino acid residues and a mature protein of ...
https://www.wikidoc.org/index.php/PDPR
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wikidoc
PDX1
PDX1 PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor necessary for pancreatic development, including β-cell maturation, and duodenal differentiation. In humans this protein is encoded by the PDX1 gene, which was formerly known as IPF1. # Function ## Pancre...
PDX1 PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor necessary for pancreatic development, including β-cell maturation, and duodenal differentiation. In humans this protein is encoded by the PDX1 gene, which was formerly known as IPF1.[1][2] # Function ##...
https://www.wikidoc.org/index.php/PDX1
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wikidoc
PEDF
PEDF Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functions. Found in vertebrates, this 50 kDa protein is being researched as a therapeutic candidate for treatment of such conditions as cho...
PEDF Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functions. Found in vertebrates, this 50 kDa protein is being researched as a therapeutic candidate for treatment of such conditions as ch...
https://www.wikidoc.org/index.php/PEDF
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wikidoc
PEPD
PEPD Xaa-Pro dipeptidase, also known as prolidase, is an enzyme that in humans is encoded by the PEPD gene. # Function Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism because of th...
PEPD Xaa-Pro dipeptidase, also known as prolidase, is an enzyme that in humans is encoded by the PEPD gene.[1][2][3] # Function Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism bec...
https://www.wikidoc.org/index.php/PEPD
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wikidoc
PER1
PER1 The PER1 gene encodes the period circadian protein homolog 1 protein in humans. # Function The PER1 protein is important to the maintenance of circadian rhythms in cells, and may also play a role in the development of cancer. This gene is a member of the period family of genes. It is expressed with a daily oscill...
PER1 The PER1 gene encodes the period circadian protein homolog 1 protein in humans.[1] # Function The PER1 protein is important to the maintenance of circadian rhythms in cells, and may also play a role in the development of cancer. This gene is a member of the period family of genes. It is expressed with a daily os...
https://www.wikidoc.org/index.php/PER1
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wikidoc
PER2
PER2 PER2 is a protein in mammals encoded by the PER2 gene. PER2 is noted for its major role in circadian rhythms. # Discovery The per gene was first discovered using forward genetics in Drosophilla melanogaster in 1971. This led to experiments in mammals that found Per2 in humans. Mammalian Per2 was discovered by Alb...
PER2 PER2 is a protein in mammals encoded by the PER2 gene. PER2 is noted for its major role in circadian rhythms.[1][2] # Discovery The per gene was first discovered using forward genetics in Drosophilla melanogaster in 1971. This led to experiments in mammals that found Per2 in humans. Mammalian Per2 was discovered...
https://www.wikidoc.org/index.php/PER2
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wikidoc
PER3
PER3 The PER3 gene encodes the period circadian protein homolog 3 protein in humans. PER3 is a paralog to the PER1 and PER2 genes. It is a circadian gene associate with delayed sleep phase syndrome in humans. # History The Per3 gene was independently cloned by two research groups (Kobe University School of Medicine an...
PER3 The PER3 gene encodes the period circadian protein homolog 3 protein in humans.[1] PER3 is a paralog to the PER1 and PER2 genes. It is a circadian gene associate with delayed sleep phase syndrome in humans.[2] # History The Per3 gene was independently cloned by two research groups (Kobe University School of Medi...
https://www.wikidoc.org/index.php/PER3
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wikidoc
PETN
PETN # Overview Pentaerythritol tetranitrate (PETN), also known as PENT, PENTA, TEN, corpent, penthrite (or—rarely and primarily in German—as nitropenta), is the nitrate ester of pentaerythritol, and is structurally very similar to nitroglycerin. Penta refers to the five carbon atoms of the neopentane skeleton. PETN i...
PETN Template:Explosivebox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Pentaerythritol tetranitrate (PETN), also known as PENT, PENTA, TEN, corpent, penthrite (or—rarely and primarily in German—as nitropenta), is the nitrate ester of pentaerythritol, and is structurally very similar to nitroglycerin...
https://www.wikidoc.org/index.php/PETN
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wikidoc
PEX5
PEX5 Peroxisomal targeting signal 1 receptor (PTS1R) is a protein that in humans is encoded by the PEX5 gene. PTS1R is a peroxisomal targeting sequence involved in the specific transport of molecules for oxidation inside the peroxisome. SKL binds to PTS1R in the cytosol followed by binding to the Pex14p receptor allowi...
PEX5 Peroxisomal targeting signal 1 receptor (PTS1R) is a protein that in humans is encoded by the PEX5 gene.[1] PTS1R is a peroxisomal targeting sequence involved in the specific transport of molecules for oxidation inside the peroxisome. SKL binds to PTS1R in the cytosol followed by binding to the Pex14p receptor al...
https://www.wikidoc.org/index.php/PEX5
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wikidoc
PEX6
PEX6 Peroxisome assembly factor 2 is a protein that in humans is encoded by the PEX6 gene. PEX6 is an AAA ATPase that localizes to the peroxisome. PEX6 forms a hexamer with PEX1 and is recruited to the membrane by PEX26. # Function From yeast to plants to humans, there is only one verified function of PEX6; PEX6 (and ...
PEX6 Peroxisome assembly factor 2 is a protein that in humans is encoded by the PEX6 gene.[1][2] PEX6 is an AAA ATPase that localizes to the peroxisome. PEX6 forms a hexamer with PEX1[3][4] and is recruited to the membrane by PEX26.[5] # Function From yeast to plants to humans, there is only one verified function of ...
https://www.wikidoc.org/index.php/PEX6
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wikidoc
PFKL
PFKL 6-phosphofructokinase, liver type (PFKL) is an enzyme that in humans is encoded by the PFKL gene on chromosome 21. This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). Thi...
PFKL 6-phosphofructokinase, liver type (PFKL) is an enzyme that in humans is encoded by the PFKL gene on chromosome 21.[1] This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis)....
https://www.wikidoc.org/index.php/PFKL
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wikidoc
PFKP
PFKP Phosphofructokinase, platelet, also known as PFKP is an enzyme which in humans is encoded by the PFKP gene. # Function The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose 6-pho...
PFKP Phosphofructokinase, platelet, also known as PFKP is an enzyme which in humans is encoded by the PFKP gene.[1] # Function The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose 6...
https://www.wikidoc.org/index.php/PFKP
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wikidoc
PFN2
PFN2 Profilin-2 is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript va...
PFN2 Profilin-2 is a protein that in humans is encoded by the PFN2 gene.[1][2][3] The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced tra...
https://www.wikidoc.org/index.php/PFN2
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wikidoc
pFPP
pFPP Parafluorophenylpiperazine (flippiperazine, fluoperazine, pFPP, 4-FPP) is a piperazine derivative with mildly hallucinogenic and euphoric effects which has been sold as an ingredient in legal recreational drugs known as "Party pills", initially in New Zealand and subsequently in other countries around the world. p...
pFPP Parafluorophenylpiperazine (flippiperazine, fluoperazine, pFPP, 4-FPP) is a piperazine derivative with mildly hallucinogenic and euphoric effects[1][2] which has been sold as an ingredient in legal recreational drugs known as "Party pills", initially in New Zealand and subsequently in other countries around the w...
https://www.wikidoc.org/index.php/PFPP