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Kidney coex contain
[ "Renal pyramids", "Malpighian corpuscles", "Renal papilla", "Minor calyces" ]
B
Malpighian corpuscle contains bowman capsule and glomerulus which is present in renal coex. End of renal pyramids called papilla along with minor calyx is present in Renal medulla which is inner poion of kidney.
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Most common cause of death due to burns in early period is?
[ "Sepsis", "Hypovolemic shock", "Both", "None" ]
B
Ans. is 'b' i.e., Hypovolemic shock
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All the following are cardinal motor features seen in Parkinson&;s Disease Except
[ "Bradykinesia", "Intentional tremor", "Rigidity", "Postural instability" ]
B
Clinical Features of Parkinson's DiseaseCardinal MotorFeaturesOther Motor FeaturesNonmotor FeaturesBradykinesiaRest tremorRigidityGait disturbance/postural instabilityMicrographiaMasked facies (hypomimia)Reduced eye blinkingSoft voice (hypophonia)DysphagiaFreezingAnosmiaSensory disturbances (e.g., pain)Mood disorders (...
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Which of the following is absent in CREST syndrome
[ "calcinosis cutis", "Raynaud's phenomenon", "Telagiectasis", "Endocrine disorders" ]
D
CREST Syndrome is acronym of Five major findings: Calcinosis cutis, Raynaud's phenomenon, Esophageal dysfunction, Sclerodoctyly and Telengiectasiasis
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which vitamin in high doses causes macular oedema and macular cyst
[ "vitamin A", "D", "E", "NIACIN" ]
D
Drugscause cystoid macular edema * Epinephrine *NIACIN *Paclitaxel *PG Analogs * Tamoxifen * Timslol REF : AK KHURANA 7TH ED
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Due to decelerations, aoa can be ruptured at places where it is fixed except:
[ "At ligamentum aeriosum", "Behind the esophagus", "Behind the crura of diaphragm", "Aoic valve" ]
B
Ans is 'b' i.e. Behind the esophagus "The majority of blunt injuries to the thoracic aoa occur at aoic isthmus just distal to the left subclan aery. Other locations include the transverse arch, proximal ascending aoa, and descending aoa just proximal to the diaphragm." - Sevitt S. The mechanisms of traumatic rupture of...
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A 35-year patient recalls episodes where he smells a pungent odor, becomes sweaty and loses consciousness. His family member says while unconscious he was having facial twitching with lip-smacking movements. What is the most probable diagnosis?
[ "Focal seizures", "Hysteria", "Atonic seizures", "Myoclonic seizures" ]
A
The patient is exhibiting focal seizures which are accompanied by transient impairment of patient's ability to maintain normal contact with environment. Chewing, lip smacking, swallowing or picking movements of hands are called Automatism. Full recovery after the episode range from seconds to an hour. Due to involvemen...
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A mother is HB&;sAg positive at 32 weekds of pregnancy. What should be given to the newborn to prevent neonatal infection -
[ "Hepatitis B vaccine + immuniglobulins", "Immunoglobulins", "Hepatitis B vaccine only", "immunoglobulin followed by vaccine 1 month later" ]
A
<p> Hepatitis B vaccine and immunoglobulins are given to the newborn to prevent infection. Reference:Park&;s textbook of preventive and social medicine,K.Park,23rd edition,page no:216. <\p>
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The appearance of the colon on a barium enema is seen in
[ "Amoebiasis", "Ulcerative colitis", "Tuberculosis of the colon", "Crohn’s involvement of the colon" ]
A
null
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RPR is done for diagnosis of:
[ "Malaria", "Syphilis", "Leishmaniasis", "None" ]
B
Ans. is. 'b' i. e., Syphilis
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Odynophagia is
[ "Pain during swallowing", "Difficulty in swallowing", "Bad odour from mouth", "Psychiatric disease" ]
A
Dysphagia is difficulty in swallowing. The term odynophagia is used when swallowing causes pain. The latter is more marked in ulcerative and inflammatory lesions of food passages - oral cavity, oropharynx and oesophagus. (Ref: Textbook of diseases of ENT, PL Dhingra, 7th edition, pg no. 393)
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Relining or rebasing of complete denture is required because
[ "Denture base material abrades", "Ridge resorption is a continuous phenomenon", "It prolongs the useful Life of the denture", "All of the above" ]
D
null
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Drug X normal administered to patients at a rate of 50mg/hr. Elimination of the drug X from body takes place as Hepatic metabolism 10% Biliary secretion 10% Renal excretion 80% This drug has to be administered to A 65 years old patient Uttam Singh, with a GFR of 60ml/min.(assuming normal GFR is 1w0ml/min). Liver and bi...
[ "50mg/hr", "30mg/hr", "25mg/hr", "100mg/hr" ]
B
Ref-Goodman and Gillman 12/e p36-37 In this question 80 percent of drug is eliminated by renal route and 20percent by non-renal routes (10 percent by hepatic metabolism and 10 percent by biliary secretion) . This patient has 50 percent renal function (60 ml/ min of GFR instead of 120 ml/min). Thus, the drug that can be...
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A newborn baby refuses breast milk since the 2nd day of bih but accepts glucose-water, develops vomiting and severe jaundice by the 5th day. Benedict's test was positive for urine and blood glucose was low. The most likely cause is due to the deficiency of
[ "Galactokinase", "Aldose reductase", "UDP galactose 4 epimerase", "Galactose 1 phosphate uridyl transferase" ]
D
The above clinical features suggest a disorder of galactose metabolism. Galactose-1-phosphate uridyl transferase deficiency leads to classical galactosemia. It is an autosomal recessive disorder. Clinical features : Accumulation of galactose-1-phosphate in the liver causes liver damage & leads to hepatomegaly, vomiting...
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A 15 year old boy complains of jerky movements which gets precipitated during awakening in the morning. There is no history of loss of conciousness. EEG showed 4-6 / second spike and wave pattern. What is the child suffering from
[ "Lennox Gestaut syndrome", "Juvenile Myoclonic Epilepsy", "Rolandic epilepsy", "West syndrome" ]
B
Juvenile Myoclonic Epilepsy Seen in adolescence age group Myoclonic jerks seen in morning EEG: 4-6 / seconds spike and wave pattern.
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Dose of rTPA in ishaemic stroke is?
[ "6O mg", "90 mg", "100 mg", "120 mg" ]
B
*-PA(recombinant tissue plasminogen activator) is administered as 0.9mg/kg IV(max. 90 mg)IV as 10% of total dose by bolus ,followed by remainder as total dose over 1hr. Ref Harrison20th edition pg 2445
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Antibody against BP 230 and BP 180 seen in
[ "Pemphigus vulgaris", "Bullous pemphigoid", "Dermatitis herpetiformis", "Hailey-Hailey Disease" ]
B
BP 230 / BPAg1 and BP 180/BPAg2 are antigens in the DEJ involved in Bullous Pemphigoid.
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In fracture shaft of femur, which nail is commonly used for ORIF?
[ "Kuntscber nail", "Austin Moore pin", "K- wire", "Smith-Peterson nail" ]
A
Ans: A (Kuntscher nail) Ref : " Wheeless' Textbook of Orthopaedics - Intramedullary Nailing of Femoral Shaft Fractures Duke Orthopaedics. & Watson-Jones Fractures and Joint Injuries, 7th editionExplanation:Kiintscher nail is an internal fixation device used to maintain the position of the fracture fragments during heal...
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Eales' disease is best treated with:
[ "Antitubercular drugs", "Steroids", "Antibiotic drops", "Antibiotics systemically" ]
B
Ans. Steroids
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A young child of 7 years age is seen with indurated ulcers, lymphadenopathy and fever. The likely treatment is:
[ "Symptomatic treatment", "Systemic antibiotics", "Excise the lesion", "I.v. Fluids" ]
A
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Antiepileptic drug implicated in causing toxic epidermal necrolysis is :
[ "Felbamate", "Gabapentin", "Lamotrigine", "Vigabatrin" ]
C
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Inulin clearance is measured to estimate-
[ "ECF", "ICF", "Plasma volume", "GFR" ]
D
Ans. is 'd' i.e., GFR * If there be a substance that passes freely across the glomerular membane but is neither reabsorbed nor secreted by tubular activity, urinary excretion would represent the amount filtered and nothing but the amount filtered. Hence, its clearance would indicate how much plasma gets filtered every ...
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All are true about subacute combined degeneration of spinal cord except -
[ "Due to deficiency of vitamin B12", "Posterior column involvement", "Corrticospinal involvement", "Absent deep tendon reflexes" ]
D
null
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Likely size of uterus at 8 weeks post paum is
[ "100 gm", "500 gm", "700 gm", "900 gm" ]
A
Ans. is a i.e. 100 gm Weight of uterus : Immediately after delivery -- 1000 gm. At the end of 1 week -- 500 gm. At the end of 2 weeks -- 300 gm. At the end of 6 weeks it weighs -- 60 - 100 gm (Pre-pregnant state). Also Know : Immediately following delivery, the fundus is just below the umbilicus (13.5 cms above the sym...
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Commonest symptom of carcinoma bronchus is -
[ "Hemoptysis", "Dyspnoea", "Cough", "Wheezing" ]
C
null
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Confirmatory investigation for Acromegaly is:
[ "Insulin induced GH suppression", "Glucose induced GH suppression", "Random GH assay", "IGF - I level" ]
B
Answer is B (Glucose induced GU suppression): The diagnosis of Acromegaly is confirmed by demonstrating the failure of GH suppression after an oral glucose load. Diagnosis of Acromegaly IGF - I level Age and gender matched serum IGF-I level are elevated in Acromegaly. Elevated IGF-I levels are primarily used as a scree...
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The drug of choice for chemoprophylaxis in contacts of a patient of penumonic plague is -
[ "Penicillin", "Rifampicin", "Erythromycin", "Tetracycline" ]
D
Ans. is 'd' i.e., Tetracycline Chemoprophylaxis o Chemoprophylaxis refers to the administration of a drug for the purpose of preventing disease or infection. Indications for chemoprophylaxis Disease Chemoprophylaxis Cholera Tetracycline or furazolidone for house-hold contacts Conjuncitivitis Erythromycin ophthalmic oin...
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"Spider leg" deformity in excretory urogram occurs in-
[ "Hydronephrosis", "Polycystic kidney", "Uretrocele", "Renal agenesis" ]
B
null
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In apoptosis which is/are involved -
[ "Apaf-1", "Bc12", "Caspases", "All" ]
D
Ans. is 'a' i.e., Apaf-1; 'b' i.e., BCl2; 'c' i.e., Caspases
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Minimum antenatal visit as per MCH is -
[ "1", "2", "3", "4" ]
D
Ans. is 'b' i.e., 4 o Now, at least 4 antenatal visits, during pregnancy, are recommended.o In these cases, a minimum of 4 visits covering the entire period of pregnancy should be the target.151 visit at 12 weeks or as soon as pregnancy is known.2nd visit at 14-26 weeks.3rd visit at 28-34 weeks.4th visit at between 26 ...
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Donovan bodies are seen in -
[ "Leishmaniadonovani", "Chlamydia trachomatis", "Klebsiella", "Calymmatobacteriumgranulomatis" ]
D
Ans. is 'd' i.e., Calymmatobacteriumgranulomatis Granuloma inguinale or Granuloma venerum or Donovanosiso Caused by Calymmatobecterium granulomatis, a gram negative intracellular bacteria,o IP is 1- 4 weeks.o Begins as one or more subcutaneous nodules that erode through skin to produce ulcer. Ulcer has following charac...
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Not used in Health planning ?
[ "Increasing demands for resources", "Analysis of health situation", "Assessment of Resources", "Fixing priorities" ]
A
The planning cycle involves ; - analysis of the health situation - establishment of objective and goals - assessment of resources - fixing priorities - write up of formulated plan - programming and implementation - monitoring - evaluation Reference : Park's textbook of preventive and social medicine, 23rd edition, pg n...
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An outbreak of staphylococcal infection involving umbilical cords of seven newborn babies was repoed in the nursery. Bacteriological survey reveals that two nurses have a large number of Staphylococcus aureus in the nasopharynx. What test should be performed to determine whether these nurses may have been responsible f...
[ "Bacteriophage typing", "Coagulase testing", "Nasopharyngeal culture on mannitol salt agar", "Protein A typing" ]
A
Typing of S. aureus Bacteriophages of S. aureus have narrow host range For epidemiological studies, strains of S. aureus can be distinguished by their patterns of lysis by internationally recognized set of 23 standard typing phages The phage type of the strain is expressed by the designations of all the phages that lys...
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Neuromuscular disorder is related to which type of lung cancer ?
[ "Adeno carcinoma", "Squamous cell carcinoma", "Small cell carcinoma", "Bronchoavelolar carcinoma" ]
B
Answer- B. Squamous cell carcinomaMyasthenia- Bronchogenic CaCerebellar degneration- Small cell Ca of lungLambe- Eaton Syndrome- Small cell Ca of lungPeripheral neuropathy- Small cell Ca of lungDermatomyositis/ Polymyositis- Small cell Ca of lungStiffman Syndrome- GIT cancers, Breast cancer, Ovarian cancer
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In BPH most common lobe involved is
[ "Lateral", "Posterior", "Median", "Anterior" ]
C
Ans is 'c' ie Median Anatomical division of ProstateProstate has 5 lobes :Anterior lobeis a small isthmus connecting the two lateral lobes in front of the urethra.Posterior lobeit connect the two lateral lobes behind the urethra. It lies behind the median lobe and the ejaculatory ducts. Carcinomas are most common in th...
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The maximum head diameter of ISO Gatesglidden drill # 1 is equivalent to:
[ "No 50 file at Do", "No 40 file at Do", "No 60 file at Do", "No 80 file at Do" ]
A
null
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Which of the following is the clinical feature of intermittent claudication?
[ "Pain in leg", "Pain in leg on rest", "Pain in leg only on exercise", "Cyanosis of leg" ]
C
Intermittent claudication refers to pain in muscles of the lower extremity associated with walking and relieved by rest. The pain is a deep-seated ache usually in the calf muscle, which gradually progresses until the patient is compelled to stop walking. Relief of symptoms is not dependent upon sitting or other positio...
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Which of these amino acids will migrate slowest to the anode end at the physiological pH?
[ "Aspaic acid", "Glycine", "Lysine", "Valine" ]
C
At physiological pH basic aminoacid (positive charged a.a) will move slowest towards anode (positively charged electrode).Basic amino acids are: Arginine (Most basic), Lysine and Histidine (Weakly basic)
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Most common site for nasopharyngeal carcinoma
[ "Anterosuperior wall", "Nasal septum", "Vault of nasopharynx", "Fossa of Rosenmuller" ]
D
NASOPHARYNX (EPIPHARYNX) Lateral wall:- Each lateral wall presents the pharyngeal opening of eustachian tube situated 1.25 cm behind the posterior end of inferior turbinate. It is bounded above and behind by an elevation called torus tubarius raised by the cailage of the tube. Above and behind the tubal elevation is a ...
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True about pulsus paradoxus is -
[ "Arm-tongue circulation time is increased", "T Stroke volume", "seen in pericardial tamponade", "seen in severe left ventricular hea failure" ]
C
Pulsus paradoxus refers to a fall in systolic pressure >10 mmHg with inspiration that is seen in patients with pericardial tamponade but also is described in those with massive pulmonary embolism, hemorrhagic shock, severe obstructive lung disease, and tension pneumothorax. Pulsus paradoxus is measured by noting the di...
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All of the following structures forms the border of Quadrangular space, EXCEPT:
[ "Teres major", "Teres minor", "Pectoralis minor", "Long head of the triceps brachii muscle" ]
C
Structures forming the borders of Quadrangular space are teres major and teres minor muscles, long head of the triceps brachii muscle, and the humerus. Contents of this space are: axillary nerve and the posterior circumflex humeral aery. Structures forming the border of triangular space are:Teres major and teres minor ...
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Treatment of choice for cancer head of pancreas?
[ "Radiotherapy", "Chemotherapy + Radiotherapy", "Whipple's surgery", "Resection of the entire pancreas with adjuvant chemotherapy" ]
C
Ans. (c) Whipple's SurgeryRef: Bailey and Love 26th/e p. 1139* Whipple's Pancreaticoduodenectomy is the Surgical Treatment of Choice for Distal CBD cancer, Periampullary cancer and Pancreatic head cancer
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Active immunity is not acquired by-
[ "Infection", "Vaccination", "Immunoglobulin transfer", "Sub-clinical infection" ]
C
Immunoglobulin transfer is type of passive immunity bcz there is no active paicipation of immune system in making antibodies. Differences between passive and active immunity Active immunity Passive immunity 1. Produced actively by host's immune system No active host paicipation; received passively 2. Antibodies induced...
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65 year old female presented to OPD with complaint of abdominal pain just after eating food , episodes of vomiting and diarrhea. She gave history of Coronary aery disease from last 20 years . BP - 160/100 mm Hg , pulse- 80/min .On abdominal examination, there is no tenderness or rigidity. What shall be the most likely ...
[ "Peptic ulcer", "Wilkie's disease", "Ulcerative colitis", "Chronic mesenteric ischemia" ]
D
CHRONIC MESENTERIC ISCHEMIA MC cause - Advanced atherosclerosis of multiple mesenteric vessels Risk factors Positive family history Hypeension Smoking Hypercholesterolemia C/F Post prandial abdominal pain Lasts for 15-45 min D/t ischemia of mesenteric vessels as there will be increase demand for blood after meals Diffu...
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Karyotyping is useful in the diagnosis of?
[ "Autosomal recessive disorders", "Chromosomal abnormalities", "X-linked recessive disorders", "Biochemical abnormalities" ]
B
Karyotyping is the study of chromosomes and is used in cytogenetics to study the chromosomal abnormalities. After arresting the cells in metaphase the chromosomes are examined to see for: • Change in Number of chromosomes - To detect abnormalities in chromosome numbers such as aneuploidy (trisomy, tetrasomy), polyploid...
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A 50-year-old diabetic patient with asymptomatic gallstone (>3 cm) will be best treated by?
[ "Early surgery", "Bile salt treatment", "ESWL", "Waiting till it becomes symptomatic" ]
A
Ans. is 'a' i.e., Early surgery
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An AIDS patient presents with fistula - in- ano. His CD4 count is below 50. What is the treatment of choice -
[ "Seton", "Fistulectomy", "None", "Both" ]
A
Ans. is 'a' i.e., Seton
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Which of the following dietary supplements is recommended for a pregnant lady on Heparin?
[ "Folic acid", "Calcium", "Zinc", "Copper" ]
B
Heparin tends to reduce the calcium levels and cause bone de-mineralisation leading to osteoporosis. With high doses, heparin tends to affect the vitamin D metabolites in the blood. This effect is more pronounced in pregnant patients where the calcium levels fall even with low doses of heparin. Hence pregnant patients ...
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Carbon monoxide diffusion capacity decreases in all, except :
[ "Emphysema", "Primary pulmonary hypeension", "Alveolar haemorrhage", "Infiltrative lung disease" ]
C
Answer is C (Alveolar hemorrhage): An elevated D Lco is characteristic of alveolar haemorrhage as in Good pastures syndrome. Hemoglobin contained in erythrocytes in alveolar lumen binds carbon monoxide, so that exhaled CO concentration is diminished and the measured Di increased. Diffusion capacity This is measured by ...
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Which type ofAmyloidosis is caused by mutation of the transthyretin protein ?
[ "Familial Mediterranean fever", "Familial amyloidotic polyneuropathy", "Dialysis associated amyloidosis", "Prion protein associated amyloidosis" ]
B
Ans. is 'b' i.e., Familial Amyloidotic Neuropathy
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Which part of ICA does not give any branch-
[ "Cervical", "Petrous", "Cavernous", "Cerebral" ]
A
null
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Intrahepatic perisinusoidal portal hypertension is classically caused by?
[ "Alcoholic hepatitis", "Schistosomiasis", "Budd-Chiari syndrome", "All of the above" ]
B
Ans. b (Schistosomiasis) (Ref: Harrison's Internal medicine 18th/Ch. 308, 219)SCHISTOSOMIASIS: "Pipe-stem" fibrosis in presinusoidal space with portal hypertension.ALCOHOLIC HEPATITIS : Accumulation of fat occurs initially in perevenular fibrosis, giant mitochondria etc.BUDD - CHIARI SYNDROME: Form of Acute congestive ...
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What should be the length of post for posterior teeth:
[ "Maximum 7mm below the canal orifice.", "Maximum 5 mm below the canal orifice.", "2/3 to the root length.", "All of the above." ]
A
For anterior teeth post length should be 2/3-3/4of root length.
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Notochord develops by
[ "8 weeks of pregnancy", "24 weeks of pregnancy", "14-21 days post conception", "2 weeks post conception" ]
C
(C) 14-21 days post conception [Grays40-184; IBS7-47# Genesis of the notochord:> Notochord develops in 3rd week.> Around the 19th day cells that invade into the primitive node region & migrate along the median line cranially from the chordal process (also known as the axial process).> On the 25th day 9 the chordal plat...
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A patient in labor ward was given opioid analgesic. Which drug should be kept ready for emergency?
[ "Naloxone", "Lignocaine", "Diphenhydramine", "Fentanyl" ]
A
ANS. A# Opioid antagonists1. Naloxone2. Natrexone3. Nalmefene# Clinical uses of Naloxone1. Drug of choice for morphine poisoning (0.4-0.8 mg IV every 2-3 min; max 10 mg)2. To reverse the respiratory depression due to intraoperative use of opioids3. Diagnosis of opioid dependence4. Partially reverses alcohol intoxicatio...
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Which of the following statements regarding live vaccines is false -
[ "Two live vaccines cannot be administered simultaneously", "Booster doses are not required when live vaccines are administered", "Single dose gives life long immunity", "Live vaccine contains both major and minor antigens" ]
A
Ans. is 'a' i.e., Two live vaccines cannot be administered simultaneously Two live vaccines can be administered simultaneously. "When two live vaccines are required they should be given either simultaneously at different sites or with an interval of at least 3 weeks". Advantages of live vaccine o Live vaccines are more...
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A 45 year old female patient reports to the clinic with a history of pain with tooth 37. The tooth appears normal on clinical and radiographic examination except for the fact that pain occurs on biting on a hard object and then releasing the bite. The most probable cause for the pain may be
[ "Occult caries", "Periodontitis", "Cracked tooth", "Maxillary sinusitis" ]
C
null
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Most common frequency of Tuning fork used in ENT:
[ "256 Hz", "512 Hz", "1024 Hz", "2048 Hz" ]
B
Ans. (b) 512 HzRef: Dhingra's ENT 5th ed. / 26* Tuning fork test can be performed using tuning fork of different frequencies such as: 128, 256, 512, 1024, 2048, 4096 Hz.* MC used/ ideal for routine clinical practice is of 512 Hz.* Tuning fork of lower frequencies produce sense of bone vibration while those of higher fr...
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Eisenmenger syndrome - True are A/E aEUR'
[ "Pulmonary veins are not distended", "RV & LV walls come back to normal size", "Dilatation of central pulmonary aery", "Peripheral pruning of pulmonary aeries" ]
B
RV & LV walls come back to normal size aiitns pgmee answers & explanations - May 2010 In Eisenmenger's syndrome pulmonary vascular resistance increases because of increased shear stress on pulmonary aerioles. Pulmonary hypeension in Eisenmenger Syndrome Early in disease Result of markedly increased blood flow (hyperkin...
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True about Vitamin K
[ "It is required for synthesis of factor VII", "Long term use of antimicrobials can cause deficiency of vitamin K", "It is a water soluble vitamin", "DVT is associated with vitamin K deficiency" ]
B
null
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In a 10-year-old child the lower canines are trying to erupt in 2mm insufficient space. The primary molars are large and firmly fixed. The 1st premolars are also erupting. The treatment of choice is:
[ "Remove primary 2nd molars", "Place a removable bite-opener", "Remove 1st premolars", "Mesial stripping of primary 2nd molars" ]
D
null
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A 23-year-old lady presents with acute right sided lower abdominal pain since 4 hours. There is tenderness at McBurney's point. Which investigation is best suited to confirm the diagnosis of appendicitis
[ "CT scan", "Plain X-ray", "Serum ESR", "MRI abdomen" ]
A
Ans. (a) CT scanRef: Sabiston 20th edition, Page 1299Various investigations done for acute appendicitis:* X-ray abdomen erect -- Fecalith can be seen in 5% cases only* USG abdomen -- noncompressible appendix +sensitivity +78-83%, Specificity = 83-93%.* CECT abdomen with only IV contrast -- sensitivity and specificity i...
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The cross linking agent of polysulphide rubber base impression material is
[ "Aromatic sulfonate esters", "Stannous octate", "Platinum salt catalyst", "Lead dioxide" ]
D
null
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Carey coomb murmur is seen in -
[ "Constrictive pericarditis", "Acute rheumatic carditis", "cardiomyopathy", "cardiac tamponade" ]
B
A sho, mid-diastolic murmur is rarely heard during an episodeof acute rheumatic fever (Carey-Coombs murmur) and probably isdue to flow through an edematous mitral valve. An opening snapis not present in the acute phase, and the murmur dissipates withresolution of the acute attack. Complete hea block with dyssynchronous...
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In myocardial infarction the infarct accquires hyperemic rim with an yellow centre at ?
[ "3-7 days", "10-20 days", "7-14 days", "1-2 hours" ]
A
Ans. is 'a' i.e., 3-7 days
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One of the following activities is not mediated through b2 adrenergic receptors -
[ "Stimulation of lipolysis", "Inreased hepatic gluconeogenesis", "Increased muscle glycogenolysis", "Smooth muscle relaxation" ]
A
Ans. 'a' i.e., Stimulation of lipolysis o Lipolysis is mediated by beta 3 receptors whereas other actions are done by stimulation of beta 2 receptors.]
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Abatacept is a new drug approved for:
[ "SLE", "Rheumatoid arthritis", "Sjogren syndrome", "Scleroderma" ]
B
Ans. (B) Rheumatoid arthritis(Ref: Harrison 18th/2748)Abatacept is a co-stimulation inhibitor. Two signals are required for activation of T-cells:1. Main signal: Interaction of T-cell receptor (TCR) with MHC of antigen presenting cells (APC)2. Co-stimulatory signal: Interaction of CD 28 of T-cells with CD-80/86 of APC....
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Intra epidermal blisters are seen in:
[ "Bullous pemphigoid", "Pemphigus folliaceous", "Dermatitis herpeteformis", "Bullous SLE" ]
B
B i.e. Pemphigus folliaceous
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Wahin tumour is:
[ "Adenolymphoma of parotid gland", "Pleomorphic adenoma of parotid", "Carcinoma of parotid", "Carcinoma of submandibular salivary gland" ]
A
Wahin Tumor: Papillary Cystadenoma Lymphomatosum Benign neoplasm of salivary gland Arises almost exclusively in parotid gland Round to oval encapsulated masses, 2 to 5 cm in diameter M/E -These spaces are lined by a double layer of neoplastic epithelial cells which might have germinal centres, resting on a dense lympho...
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Lymphangiography of the leg is performed by
[ "An injection of sodium diatrizoate subcutaneously between the toes", "Injecting sodium diatrizoate retrogardely under pressure into a small vein on the dorsum of foot", "Dissecting lymphatics through an incision on the dorsum of foot", "The use of an infusion pump" ]
C
Direct-contrast lymphangiography provides the finest details of the lymphatic anatomy. However, it is an invasive study that involves exposure and cannulation of lymphatics at the dorsum of the forefoot, followed by slow injection of contrast medium (ethiodized oil). The procedure is tedious, the cannulation often nece...
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Oral Hairy Leukoplakia is associated with:
[ "HIV", "HPV", "EBV", "CMV" ]
C
EBV
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Pasteurization is ____________ disinfection
[ "Precurrent", "Concurrent", "Preconcurrent", "Terminal" ]
A
Disinfection of milk by pasteurization, water by chlorine and handwashing may be cited as examples of precurrent infection. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 140
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Most specific indicator of liver injury?
[ "ALT", "AST", "SAP", "5' nucleotidase" ]
A
Most specific indicator of liver injury is: ALT: SGPT (product present in cytosol that come in blood due to injury) AST: SGOT, present in cardiac tissue/liver so it's not specific SAP: (Cholestasis marker) Do not indicate hepatocyte necrosis 5' nucleotidase: Cholestasis marker
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What is the colour-coding of bag in hospitals to dispose of human anatomical wastes such as body pas
[ "Yellow", "Black", "Red", "Blue" ]
A
Human anatomical wastes including human tissues, organs and body pas come under category no.1. - category no 1 wastes are discarded in a yellow colour plastic bag. Reference: Park&;s textbook of preventive and social medicine, 23rd edition, pg no: 793,794
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All of the following statements about synol fluid are true. Except -
[ "Secreted primarily by type A synol cells", "Follows Non - Newtonian fluid kinetics", "Contains hyaluronic acid", "Viscosity is variable" ]
A
synol fluid is plasma transudate from synol capillaries,modified by secretory activities of type-B synol lining cells. REF:Turek's.6 th edition.page no.152.
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A 31-year-old woman has had a persistent fever for the past 2 months. Her temperature has ranged from 38.3degC to 38.6degC on multiple occasions. On physical examination, she has diffuse abdominal pain and mild splenomegaly, but no hepatomegaly or lymphadenopathy. Laboratory studies show Hgb, 13.2 g/dL; Hct, 39.8%; MCV...
[ "Abscess", "Non-Hodgkin lymphoma", "Ovarian cystadenocarcinoma", "Sarcoidosis" ]
A
She has fever of unknown origin (FUO), at least until a record review correlated with the CT imaging suggests that the mass is a residual hemostatic sponge placed at the time of surgery. Radiopaque markers or radio-frequency identification (RFID) chips can be incorporated into such objects for identification. The mild ...
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Analysis of routine measurement is aimed at detecting changes in environment -
[ "Monitoring", "Surveillence", "Isolation", "None" ]
A
Ans. is 'a' i.e., Monitoring Monitoringo Monitoring is the performance and analysis ofroutine measurements aimed at detecting changes in the environment or health status ofpopulation, e.g. monitoring of air pollution, wrater quality, and growth & nutritional status.Surveillanceo Surveillance is the continuous scrutiny ...
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Delayed afterdepolarization implies?
[ "Increased intracellular Ca\"", "Excessive catecholamines", "Digitalis toxicity", "All of the above" ]
D
Ans. is 'd' i.e., All of the aboveDelayed afterdepolarizations occur in late phase 3 or early phase 4 when the action potential is nearly of fully repolarized.The mechanism is poorly understood; however, this type of arrhythmia is found to be associated with high intracellular Ca++ concentrations as occurs with digital...
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Other name of Sex-Linked Graft Rejection ?
[ "Eichwald Silmser effect", "Schultz Dale phenomena", "Schwazman reaction", "Theobald Smith phenomenon" ]
A
EICHWALD SILMSER EFFECT - Sex linked graft rejection Unilateral sex linked histo-incompatibility =In a normal scenario , transplants between Siblings are accepted =When the donor is a male and the recipient is a female , graft is not accepted i.e. graft rejection occurs. This rejection occurs as the grafted male tissue...
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Guiding plane in RPD should be located at:
[ "In between edentulous space", "Abutment surface adjacent to an edentulous area", "Edentulous areas", "Abutment area" ]
B
null
train
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Long term adverse effect of tamoxifen is
[ "Weight gain", "Osteoporosis", "Venous thrombosis", "Breast cancer" ]
C
TAMOXIFEN - It is SERM - Actions Bone - | formation of bone; decrease risk of osteoporosis Blood - | HDL Breast -Decrease risk of breast cancer Liver - | clotting factor leading to thromboembolism Endometrium - | risk of endometrial cancer
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Example of Type IV hypersensitivity is -
[ "Serum sickness", "Granulomatous reaction", "Shwartzman reaction", "Arthus reaction" ]
B
Ans. (b) Granulomatous reaction(Ref: Robbins 9th/pg 208-211; 8th/pg 205-208; Illustrated Dictionary of Immunology by M.P.Arora - Page 501)Granulomatous reaction is an example of type IV hypersensitivitySerum sickness & Arthus reactions are examples of type III hypersensitivityShwartzman reaction is a non-immunologic ph...
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The treatment for acute periodontal abscess is
[ "The drainage of abscess through incision only", "Incision & drainage followed by flap surgery after the symptoms subside", "Incision should not be given through ultrasonic tip", "Incision should be given only external level" ]
A
null
train
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Nerve related to anatomical snuff box ?
[ "Ulnar", "Median", "Superficial branch of radial", "Axillary" ]
C
ANATOMICAL SNUFF BOX is a triangular depression on the lateral side of the wrist. BOUNDARIES: ANTERIOR-Tendons of abductor pollicis longus and extensor pollicis brevis. POSTERIOR: Tendon of extensor pollicis longus Limited above by Styloid process of the radius. FLOOR: Scaphoid and Trapezium. CONTENTS: Superficial bran...
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Annexin V is a marker of aEUR'
[ "Apoptosis", "Necrosis", "Aherosclerosis", "Inflammation" ]
A
Apoptosis Annexin V assays provides simple and effective method to detect apoptosis at a very early stage. This assay makes advantage of the fact that phosphatidylserine (PS) is translocated from the inner (cytoplasmic) leaflet of the plasma membrane to the outer (cell surface) leaflet soon after the induction of apopt...
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Pott puffy tumour occurs as complication of which sinusitis:
[ "Frontal", "Sphenoid", "Ethmoid", "None of the above" ]
A
If infection in the frontal sinus spreads to the marrow of the frontal bone, localized osteomyelitis with bone destruction can result in a doughy swelling of the forehead classically described as Pott puffy tumour.
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Positive shick's test indicates that person is ?
[ "Immune to diptheria", "Hypersensitive to diptheria", "Susceptible to diptheria", "Carrier of diptheria" ]
C
Ans. is 'c' i.e., Susceptible to diphtheria Shick test . Shick test is no longer in use. It was used for the susceptibility of for diphtheria. . It was an intradermal test, in which after intradermal injections of diphtheria toxin in one forearm (usually left) and toxoid in other forearm two readings were taken one at ...
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According to Stanford-Binet test, non trainable type of mental retardation has an IQ of:
[ "Below 20", "Between 36-51", "Above 51", "Between 90 - 130" ]
A
null
train
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A farmer was brought to the casualty with restlessness & agitation. Examination shows temp. 103deg F, flushed face, pupils dilated and fixed. The diagnosis is
[ "Dhatura poisoning", "Organophosphorus poisoning", "Diazepam poisoning", "Opium poisoning" ]
A
A i.e. Dhatura poisoning
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High-altitude acclimatization may be facilitated by all except?
[ "Increased production of red blood cells", "Increased alveolar ventilation", "Growth of new blood vessels", "Growth of new skeletal muscle fibers" ]
D
Erythropoietin secretion increases promptly on ascent to high altitude and then falls somewhat over the following 4 days as the ventilatory response increases and the aerial PO2 rises. The increase in circulating red blood cells triggered by the erythropoietin begins in 2-3 days and is sustained as long as the individu...
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Treatment of odontoma in child patient consists of:
[ "No treatment.", "Wait and watch.", "Surgical removal.", "None." ]
C
null
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Selenium is a co-factor for
[ "Glutathione peroxidase", "Glutathione reductase", "Glutathione synthetase", "Glutathione dehydrogenase" ]
A
Selenium is component of selenocysteine, glutathione peroxidase, thioredoxin, deiodinaseThe peroxides that are formed by radical damage to lipids in membranes and plasma lipoproteins are reduced to hydroxy fatty acids by glutathione peroxidase.Ref: Harper&;s Biochemistry; 30th edition; Pg: 567
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Folic acid is absorbed from
[ "Duodenum", "Stomach", "Ileum", "Proximal Jejunum" ]
D
Ans- D Proximal Jejunum
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Total alveolar ventilation volume (in L/min) is
[ "1.5", "3.5", "4.2", "5" ]
C
Ans. (c) 4.2(Ref: Ganong, 25th ed/p.629)Alveolar ventilation is 4.2L/minAlveolar ventilation = respiratory rate * (tidal volume - dead space) =12(500-150)=4.2L/min
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Snake eye appearance is resembled by occlusal view of which tooth
[ "Upper 1st premolar", "Lower 1stpremolar", "Upper 2nd premolar", "Lower 2nd premolar" ]
B
null
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Thioacetazone has cross resistance with ?
[ "INH", "Rifampicin", "Ethionamide", "Ethambutol" ]
C
Ans. is'c'i.e., Ethionamide(Ref; Essentials in tuberculosis P. 468)Thioacetazone has cross-resistance with ethionamide/prothionamide."A cross resistance between ethionamide and thiacetazone is repoed.Perchlozone also shows cross resistance with thiacetazone.
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All of the following are true about Primary Biliary Cirrhosis except?
[ "Increase 5'- nucleotidase", "Median age of presentation is 50 years", "Most common cause of cholangitis in children", "PBC frequently associated with CREST syndrome" ]
C
Primary biliary cirrhosis- Characterized by chronic inflammation and fibrous obliteration of intrahepatic bile ductules. Associated with autoimmune disorders- CREST syndrome, Sicca syndrome, Autoimmune thyroiditis, Type-1 Diabetes mellitus and IgA deficiency. Mostly seen in females Age is 35-60 yrs C/F-Pruritis, jaundi...
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Which of the following muscle produces abduction of vocal cord? (Repeat)
[ "Transverse arytenoid", "Posterior cricoaryteniod", "Lateral cricoarytenoid", "Oblique arytenoid" ]
B
Ans: B (Posterior cricoarytenoid) Ref: Gray's Anatomy, 39th edition. 2008.Page 642Explanation:Posterior cricoarytenoid :The only muscle produce abduction of vocal cord (open the rimu glottides and it becomes triangular in shape)So called the Safety muscle of larynxOrigin: Posterior surface of lamina of cricoid cartilag...
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A 25 years old man marries a 13 years girl and has intercourse with her, this constitutes rape as she is-
[ "<15 years age", "<14 years age", "<21 years age", "No consent taken from wife" ]
A
Sexual intercourse with wife, even with her consent is rape, if she is below 15 years of age.
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WHO Global Target for Prevention and Control of Non-communicable Disease by 2025 is to decrease Hypeension by:-
[ "25%", "35%", "55%", "75%" ]
A
THE WHO NCD TARGETS (to be achieved by 2025) : Target 1: 25% relative reduction in the overall moality from cardiovascular diseases, cancer, diabetes, or chronic respiratory diseases. Target 2: At least 10% relative reduction in the harmful use of alcohol, as appropriate, within the national context. Target 3: 10% rela...
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