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What is the percentage of patients with disseminated discoid lupus erythematosus who develop SLE?
[ "2%", "22%", "52%", "82%" ]
B
The risk is higher in patients with disseminated DLE (22%) than in DLE confined to the head and neck (1.2%). Females developing DLE before the age of 40 years,with HLA-B8 in their histocompatibility type, have an increasedrisk of 'conveing' to SLE. Neither immunological nor biochemical abnormalities appear to alter the...
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What is the action of oxytocin in small doses, when used as intravenous infusion in a full term uterus?
[ "Relaxes uterus", "Induces uterine contractions", "Causes cervical dilatation", "All" ]
B
Oxytocin increases the force and frequency of uterine contractions. With low doses, full relaxation occurs in between contractions. Ref.Essentials of medical pharmacology TD Tripathi 7th edition page no.329)
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Primordial prevention is done in population ?
[ "With risk factors", "Without risk factors", "Whole population with low prevalence of disease", "Population with disease" ]
B
Ans. is 'b' i.e., Without risk factors In primordial prevention, action is taken prior to emergence of risk factor, i.e. action is taken in population which has not developed risk factor.
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Sinusoidal hea rate pattern is seen in:
[ "Placenta pre", "Vasa pre", "Battledore placenta", "Succenturiate placenta" ]
B
Sinusoidal hea rate is observed in the antepaum period due to severe fetal anaemia as in Rh immunisation ,ruptured vasa prae or twin twin transfusion.It is rare in intrapaum period. Refer page no 521 of Text book of obstetrics,sheila balakrishnan,2 nd edition.
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Which is the clinical type of acute pericarditis?
[ "Serous", "Fibrinous", "Caseous", "Purulent" ]
B
Ans. is 'b' i.e., Fibrinous Classification of pericarditisClinical classificationI. Acute pericarditis (<6 weeks)a) Fibrinousb) Effusive (serous or sanguineous)II. Subacute pericarditis (6 weeks to 6 months)a) Effusinve-constrictiveb) ConstrictiveIII) Chronic pericarditis (> 6 months)a) Constrictiveb) Effusivec) Adhesi...
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3rd person auditory hallucinations are common in which of the following disorder?
[ "Schizophrenia", "OCD", "Alcohol intoxication", "LSD intoxication" ]
A
In schizophrenia, 3rd person running commentary about the person's actions are most common hallucinations. Ref: Essentials of postgraduate psychiatry By JN Vyas 1st ed Pg 398
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Which of the following is associated with adult polycystic kidney disease -
[ "Berry aneurysms in Circle of Willis", "Saccular aneurysms of aorta", "Fusiform aneurysms of aorta", "Leutic aneurysms" ]
A
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All - Trans - Retinoic Acid is used in the treatment for:
[ "Acute Promyelocytic Leukemia (PML)", "Acute Lymphoid Leukemia (ALL)", "Chronic Myeloid Leukemia (CML)", "Chronic Lymphoid Leukemia (CLL)" ]
A
All -Trans- Retinoic Acid is used in the treatment for Acute Promyelocytic Leukemia (PML) Ref: Harrison's Principles of Internal Medicine, 16th Edition, Page 636; Manual of Practical Medicine By R Alagappan, 3rd Edition, Page 347
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All of the following are indices to define obesity, EXCEPT:
[ "Chandler's index", "Corpulence index", "Quetlet's index", "Body mass index" ]
A
Various indices used to detect obesity include: Corpulence index Quetlet's index/ Body mass index Ponderal index Broca index Lorentz's formula Ref: Park 21st edition, page 369.
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Most common site of sub ependymal astrocytoma
[ "Trigone of lateral ventricle", "Foramen of Munro", "Temporal horn of lateral ventricle", "4th ventricle" ]
B
Ans. is 'b' i.e. Foramen of Munro Most common site of subependymal astrocytoma is Foramen of monro.
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Which of the following is an anti-pseudomonal drug of penicillin class: March 2013
[ "Nafcillin", "Dicloxacillin", "Piperacillin", "Cloxacillin" ]
C
Ans. C i.e. Piperacillin Extended-spectrum penicillin It is a group of antibiotics that has the widest antibacterial spectrum of all penicillins. It is also called antipseudomonal penicillins. This group includes the Aminopenicillins: Amoxicillin Ampicillin Epicillin - Carboxypenicillins: Ticarcillin Carbenicillin Urei...
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Inferior oblique muscle of eye is supplied by
[ "Oculomotor nerve", "Abducent nerve", "Trochlear nerve", "Facial nerve" ]
A
Ref BDC volume 3,6th edition pg 208NERVE SUPPLY:The superior oblique is supplied by trochlear nerveThe lateral rectus is supplied by abducent nerveThe superior rectus, medial rectus, inferior rectus and inferior oblique is supplied by occulomotor nerve
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Antitrypsin deficiency is associated with- (a) (b)
[ "Restrictive lung pathology", "Cystric fibrosis", "Emphysema", "Carcinoma" ]
C
Pathogenesis of Emphysema The most accepted theory in the pathogenesis of emphysema is protease - antiprotease mechanism which is responsible in the pathogenesis of two common forms of emphysema, i.e. centriacinar and panacinar. The alveolar wall destruction results from an imbalance between proteases (mainly elastase...
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Initial fluid of choice in treatment of hypovolemia in patients presenting after trauma is -
[ "Colloid", "Blood", "Plasma expanders", "Crytalloid" ]
D
Ans. is 'd' i.e., Crystalloid * Initial fluid of choice in treatment of hypovolemia in patients presenting after trauma crytalloid. Particularly in patients presenting after truam normal saline is preferred over hartmans solution.
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Substance with same atomic number but different mass number
[ "Isotope", "Isobar", "Atom", "Mineral" ]
A
Ans. a (Isotope). (Ref. Radioactive isotope in medicine and biology by Quimby, 2nd ed., 26)TermDefinitionIsotopesAtoms having same atomic numbers, different mass numbers (hence different neutron number) e.g., 17CI35, 17CI37 (same no.of protons and electrons)IsobarsAtoms having same mass numbers, different atomic number...
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A patient having multiple Gall stones and shows 8 mm dilation and 4 stones in CBD, best treatment modalities are -
[ "Cholecystectomy with choledocholithotomy at same setting", "ESWL", "Cholecystectomy and wait for ERCP", "All" ]
A
Answer (a) Cholecystectomy with choledocholithotomy done at same sitting Management of suspected or proven CBD stones associated with gall bladder stones For gallstones - laparoscopic cholecystectomy is the procedure of choice. For CBD stones two things can be done: 1) If the surgeon is experienced in laparoscopic tech...
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Tbilisi phage is used for identification of-
[ "Bacillus", "Corynebacterium", "Salmonella", "Brucella" ]
D
Ans. D. Brucella.The species identification of Brucella is very complex and is based on-a. Relative proportions of 2 antigens, A and Mb. CO2 requirementc. H2 S productiond. Urease enzymee. Phage lysis (Tbilisi phage)f. Sensitivity to dyes.
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Risk of failure of cold chain maintainance is more at
[ "District hospitals", "PHCs", "Subcentre level", "CHCs" ]
C
null
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Which of the following anticancer drugs acts by hypomethylation ?
[ "Gemcitabine", "5–FU", "Decitabine", "Homoharringtonine" ]
C
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Hypochloremic alkalosis is a complication of -a) Congenital pyloric stenosisb) Vomitingc) Haematemesisd) Aspirin intoxication
[ "ad", "ab", "bd", "cd" ]
B
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'Itch is disease' is true for ?
[ "Atopic dermatitis", "Insect bites", "Seborrheic dermatitis", "Tinea cruris" ]
A
A i.e. Atopic dermatitis
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Risk factors for malignant change in an asymptomatic patient with a gall bladder polyp on ultrasound include all of the following, Except:
[ "Age > 60 years", "Rapid increase in size of polyp", "Size of polyp > 5 mm", "Associated Gall stones" ]
C
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Salter's pelvic osteotomy is done for treatment of ?
[ "CTEV", "SCFE", "DDH", "None" ]
C
Ans. is 'c' i.e., DDH Treatment of CDH/DDH The aim of treatment in DDH is to achieve and maintain an early concentric reduction and maintain it until the hip becomes clinically stable and a round acetabulum cover it. Treatment plan is according to the age :? 1- 6 months of age :- Pavilk harness and/or Von-rosen splint ...
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Dreaming is common in which stage of sleep: September 2008
[ "REM", "NREM 1", "NREM 2", "NREM 3" ]
A
Ans. A: REM Humans aroused at a time when they show the EEG characteristics of REM sleep generally repo that they were dreaming, whereas individuals awakened from slow-wave sleep/ NREM do not. This observation and other evidence indicate that REM sleep and dreaming are closely associated. The tooth-grinding (bruxism) t...
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Which of the following is not caused by Oxytocin
[ "Milk ejection", "Lactogenesis", "Contraction of uterine muscles", "Myoepithelial cell contraction" ]
B
Ans. B. LactogenesisOXYTOCIN causes contraction of the myoepithelial cells that line the ducts of the breast. This squeezes the milk out of the alveoli of the lactating breast into the large ducts and then Out of nipple (milk ejection) Oxytocin also causes contraction of smooth muscle of uterus.
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Repolarization of nerve action potential is due to:
[ "Inward sodium current", "Inward potassium current", "Inward potassium current and outward sodium current", "Outward potassium current and inward sodium current" ]
D
Ans. D. Outward potassium current and inward sodium currentThe repolarization is due to the opening of voltage-gated K+ channels (K+ outward movement).During this Na+ channels rapidly enter a closed state called the inactivated state. So, few Na+ still enter during repolarization also.
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"River blindness" is caused by:
[ "Onchocera-Volvulus", "Schistoma haematobium", "Fasciola hepatica", "Opisthorchis-viverrini" ]
A
(onchocera - volvulus) Ref: 1327-HI7th)ONCHOCERCIASIS: (River blindness) is caused by the filarial nematode O valvulus* Pruritis and rash are the most frequent manifestations of onchocerciasis* Visual impairment is the most serious complication of onchocerciasis. The most common early finding is conjunctivitis with pho...
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All are true about Peyronie's disease EXCEPT:
[ "Self limiting", "Medial treatment is effective", "Association with Dupvytren's contracture", "Calcified plaques" ]
B
(Medical treatment is effective) (1399-1400-Baily & 24th) (1373-B &L 25th)PEYRONIE'S DISEASE - Common cause of erect penis.* Hard plaques of fibrosis can usually be palpated in the tunica of one or both corpora covemosa. The plaque may be calcified.* May result of past trauma, there is association with dupuytren *s con...
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In the recovery room, 1 hour after an outlet forceps delivery, a patient is found to have an 8 x 5 cm expanding, bluish & tense, painful right labia majora. The most appropriate management of this patient includes:
[ "Vaginal packing", "Vaginal exploration under GA", "Exploratory laparotomy and Internal Illiac aery Ligation", "Observation, Cold compress." ]
B
The above given history is suggestive of vulvar hematoma. Most cases can be managed conservatively, at least initially, but if the pain does not disappear and if there is suspicion of an expanding hematoma, it will be necessary to examine the areas with the patient under anesthesia and drainage in order to reduce the p...
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Which of the following inhibits transcription ?
[ "Cyclosporine", "Rapamycin", "5-Flurouracil", "Cyclophosphamide" ]
A
Ans. is 'a' i.e., Cyclosporine Cyclosporine inhibits transcription by binding to a protein called cyclophilin. This complex then inactivates calcineurin. (Calcineurin is a protein which is responsible for the transcription of cytokine gene)
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Submandibular gland is divided into superficial and deep pas by ?
[ "Digastric", "Geniohyoid", "Mylohyoid", "Stylohyoid" ]
C
Submandibular gland This walnut sized gland lies below the mandible in the anterior pa of digastric triangle. It is .1-shaped and consists of a large superficial and a small deep pas, separated by mylohyoid muscle and continuous with each other around the posterior border of mylohyoid muscle. Superficial pa It is situa...
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Which of the following tumours present with proptosis a) Neuroblastoma b) Nephroblastoma c) Germ cell tumour d) Medulloblastoma e) Meningioma
[ "abe", "acd", "cde", "abd" ]
A
Orbital tumors causing proptosis Primal), : Dermoid cyst, osteoma, lymphoma, lymphosarcoma, optic nerve glioma, optic nerve sheath meningioma, retinoblastoma Metastasis :- Breast, lung, prostate, kidney (nephroblastoma), melanoma, neuroblastoma, GIT, Ewings sarcoma, wilms tumor.
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Mutarotation refers to change in:
[ "pH", "Optical rotation", "Conductance", "Chemical properties" ]
B
Mutorotation refers to the change in the specific optical rotation representing the interconversion of α- and β- anomers of D-glucose to an equilibrium.
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Leptomeninges is formed by:
[ "Dura mater and Arachnoid", "Arachnoid and pia mater", "Dura and pia mater", "Dura, arachnoid and pia matter" ]
B
Ans. B Arachnoid and pia materRef: Netter's Clinical Anatomy, 3rd ed. pg. 25* Meninx implies all three layers--dura, arachnoid and inner pia matter.* The dura mater is called pachymeninx.* The middle arachnoid and inner pia matter is called as leptomeninges.* The arachnoid does not follow the convolutions of brain and ...
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Which of the following is the most common mutation in Ewing's sarcoma
[ "Translocation X: 18", "Translocation 11; 22", "Activative mutation of G5alpha surface protein", "Missense mutation in EXTI" ]
B
Miscellaneous bone tumors In Ewing sarcoma the common chromosomal abnormality is a translocation that causes the fusion of EWs gene on 22q12witg a member of the ETS family of transcription factors. The most common fusion paers are the FL1 gene on 11q24 and the ERG gene on 21q22. Robbins basic pathology 9th edition page...
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Third coronary aery is -
[ "Right coronary aery", "Left coronary aery", "Conus aery", "Anterior interventricular aery" ]
C
Ans. is 'c' i.e.,Conus aeryThird coronary aery is seen only in 50% of human heas. It is also called conus aery.The conus aery is a small early branch off the right coronary aery (RCA) circulation.
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Loss of inter personal communication is managed by
[ "Group conselling", "Individual counselling", "Check telecommunications", "Improving language" ]
C
Ref: 25th Ed K.Park's Textbook Of Preventive and Social Medicine
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Recall phenomenon is seen in: March 2013 (b)
[ "Radiotherapy following chemotherapy", "Surgery after radiotherapy", "Radiotherapy after surgery", "Chemotherapy following radiotherapy" ]
D
Ans. D i.e. Chemotherapy following radiotherapy Radiation recall phenomenon When patients are exposed to ceain chemotherapy agents a few weeks or months (or, rarely, even years) after completion of radiation treatment, some acute radiation reactions may re-occur. This phenomenon was first described by Dr. D'Angio, who ...
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In WHO "Road to Health" chart, upper and lower limit of represents:
[ "30 percentile for boys and 3 percentile for girls", "50 percentile for boys and 3 percentile for girls", "30 percentile for boys and 5 percentile for girls", "50 percentile for boys and 5 percentile for girls" ]
B
Ans. b. 50 percentile for boys and 3 percentile for girls (Ref: Park 23/e p545, 20/e p547-548)In WHO "Road to Health" chart, upper limit of represents 50th percentile for boys and lower limit represents 3rd percentile for girls.WHO-Home Based Growth ChartWHO growth chart has 2 reference curvesQ:Upper Reference Curve (U...
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Skin over hypothenar eminence is supplied by?
[ "Radial nerve", "Median nerve", "Anterior interosseous nerve", "Ulnar nerve" ]
D
Ulnar nerve
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All of the following are derivatives of Urogenital Sinus except
[ "Bladder", "Ejaculatory duct", "Prostatic uretha", "Membranous uretha" ]
B
null
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Which of the following is not a branch of ophthalmic nerve?
[ "Frontal nerve", "Lacrimal nerve", "Nasociliary nerve", "Middle ethmoidal nerve" ]
D
null
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Difference between postmoem staining and contusion are all, except: PGI 10; NEET 14
[ "Bluish in color", "Disappear on pressure", "Margins are regular", "Extravasation is found" ]
D
Ans. Extravasation is found
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Most common tumour of minor salivary glands is ?
[ "Muco epidermoid carcinoma", "Mixed tumour", "Squamous cell carcinoma", "Epithelioma" ]
A
Ans. is 'a' i.e., Mucoepidermoid
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Early indication of sexual maturation in females is
[ "Menarche", "Thelarche", "Pubarche", "Genital maturation" ]
B
The onset of pubey is triggered by various genetic and environmental factors. The activation of the hypothalamic-pituitary-gonadal axis leads to the production of gonadotropins ( LH & FSH) and sex steroids (estrogen & testosterone). Pubey in girls stas with Breast development (thelarche)- 8-13yrs Appearance of public h...
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True about High roughage in diet is :
[ "Decreases stool transit time", "Increase stool transit time", "Normalise stool transit", "No effect on stool transit time" ]
D
A i.e. Decreases stool transit time
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Bone affection in scurvy is due to which of the following
[ "Poor mineralization of the osteoid tissue", "Defective osteoid matrix formation", "Defective calcification in osteoid", "Increased degradation of osteoid tissue" ]
B
The most clearly established function of vitamin C is the activation of prolyl and lysyl hydroxylases from inactive precursors, allowing for hydroxylation of procollagen. Inadequately hydroxylated procollagen cannot acquire a stable helical configuration or be adequately cross-linked, so it is poorly secreted from the ...
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Chimeric DNA used for:
[ "Paternity test", "Maternity test", "Personal identification", "Organ transplantation" ]
D
Ans. (d) Organ transplantationRef: Harpers Biochemistry 30th Ed; Page No- 459* Chimeric DNA is known as Recombinant DNA.* Chimeric DNA = DNA to be cloned + Vector DNAMote* Passenger DNA: DNA to be cloned is called Passenger DNA or Foreign DNA.* Procedure to Prepare Chimeric DNA:# Both foreign DNA and Vector DNA is trea...
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Protective mechanism of inguinal canal ?
[ "Obliquity of inguinal canal", "Contraction of cremestric muscle", "Contraction of conjoint tendon", "All of the above" ]
D
Ans. is 'd' i.e., All of the aboveThere are following impoant physiological mechanisms that protect against formation of inguinal hernia with increased intra-abdominal pressure ?Shutter mechanism :The arching fibers of internal oblique and transverse abdominis (i.e. conjoint tendon) contract when the muscles of abdomen...
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All or the following are true about excitation contraction coupling except:
[ "Acetylcholine is released at the nerve terminal", "Calcium is pumped back into the sarcoplasmic reticulum during relaxation", "Calcium is released from sarcoplasmic reticulum during contraction", "Calcium binds to tropomyosin to initiate muscle contraction" ]
D
Ans. d. Calcium hinds to tropomyosin to initiate muscle contraction (Ref: Guyton 11/e p90)Calcium binds to Troponin C, not to the tropomyosin, to initiate muscle contraction.'The calcium released into the cytosol binds to Troponin C by the actin filaments, to allow cross-bridge cycling, producing force and, in some sit...
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Premature rupture of membrane is rupture :
[ "At less than 32 weeks", "Before onset of labour", "Before 2nd stage of labour", "All of the above" ]
B
Before onset of labour
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Combined indicator to reflect both acute and chronic malnutrition is
[ "Low height-for-age", "Low weight-for-height", "Low height-for-weight", "Low weight-for-age" ]
D
Indicators of undernutrition Indicator Interpretation Comment Stunting Low height-for-age Indicator of chronic malnutrition, the result of prolonged food deprivation and/ or disease or illness Wasting Low weight-for-height Suggests acute malnutrition, the result of more recent food deficit or illness Underweight Low we...
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To achieve the additional retention, following should be done while tooth preparation:
[ "Excessive occlusal preparation", "Tapered preparation", "Grooves and boxes", "Supragingival finish line" ]
C
Proximal grooves or boxes placed in healthy tooth structure are particularly effective in enhancing the resistance form of crown preparations, because these interfere with rotational movement (tipping) of the crown and thereby subject additional areas of the luting agent to compression. Ref: Stephen Rosenstiel, Martin ...
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Saponification means hydrolysis of fats by:
[ "Acid", "Alkali", "Water", "Enzymes" ]
B
null
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Which of the following is the most appropriate management of a face presentation with no fetal distress and an adequate pelvis, as determined by digital examination?
[ "Perform immediate cesarean section without labor", "Allow spontaneous labor with vaginal delivery", "Perform forceps rotation in the second stage of labor to conve mentum posterior to mentum anterior and to allow vaginal delivery", "Allow to labor spontaneously until complete cervical dilation is achieved an...
B
If Face presents with mento- anterior , it can deliver vaginally. The diameter of engagement is Sub-mentoveical, 10cms, or sub-mentobregmatic,9.5 cms, both of which suppo a normal vaginal delivery Mento posterior position has no mechanism of labor as the engaging diameter is the sterno bregmatic of 16-18cm because the ...
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The most characteristic manifestation of megaloblastic anaemia
[ "Macrocytosis", "Hyper segmented neutrophils", "Basophilic stippling", "Cabot ring" ]
A
The presence of red cells that are macrocytic and oval (macro-ovalocytes) is highly characteristic of megaloblastic anaemia.Other features are: Most macrocytes lack the central pallor of normal red cells and even appear "hyperchromic," but the MCHC is not elevated.The reticulocyte count is low. Nucleated red cell proge...
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The following features are true about membranous glomerulopathy except-
[ "Heavy proteinuria", "Hyperlipidemia", "Early onset of renal failure", "Respond to steroids" ]
C
Membranous Glomerulonephritis - Spontaneous remissions occur in 20-30% of patients and often occur late in the course which make treatment decisions difficult. One third of patients continue to have relapsing nephrotic syndrome but maintain normal renal function . Another one third develop renal failure or die from com...
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Which of the following is true regarding Mittendorf dot?
[ "Glial tissue projecting from optic disc", "Obliterated vessel running forward into the vitreous", "Obliterated vessel running forward into the vitreous", "Associated with posterior polar cataract" ]
C
Mittendorf dot is a remnant of the anterior end of hyaloid aery. It is attached to the posterior lens capsule. It is associated with posterior polar cataract. Ref: Comprehensive Ophthalmology, A. K. Khurana, 7th edition
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Propranolol should not be given to a patient on treatment with which of the following drug ?
[ "Nifedipine", "Nitrates", "ACE inhibitors", "Verapamil" ]
D
null
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Regarding stones in gall bladder the following are true except -
[ "Mixed stones are common in the west", "In Saints Triad diverticulosis of colon and hiatus hernia coexist", "Is a risk factor in the development of GB carcinoma", "90% of GB stones are radioopaque" ]
D
null
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Causes of DIC are all except :
[ "Abruption placentae", "Fat emboli", "Amniotic fluid embolism", "IUD" ]
B
Fat emboli
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River blindness is caused by -
[ "Onchocerca", "Loa loa", "Ascaria", "B. Malayi" ]
A
pathogenesis and clinical features The infective larvae deposited in the skin by the bite of the vector develop at the site to adult worms .Adult worms are seen singly, in pairs , or in tangled masses in the subcutaneous tissues ocular manifestations range from photophobia to gradual blurring of vision , progressing to...
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The most frequent cataract type seen in adult Retinitis pigmentosa patient is –
[ "PSC", "Anterior polar", "Cortical", "Mixed" ]
A
Retinitis pigmentosa is associated with posterior subcapsular cataract (PSC). "Retinal pigment degenerations such as retinitis pigmentosa , Usher's syndrome and gyrate atrophy are associated with cataract, which are usually subcapsular opacities". —Yanoff & Duker
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The American dental association (ADA) specification number for non- aqueous elastomeric dental impression material is:
[ "19", "20", "21", "26" ]
A
null
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Which of the following fatty acid have maximum hypocholesterolemic effect?
[ "Arachidonic acid", "Linolenic acid", "Linoleic acid", "Oleic acid" ]
B
Omega 3 fatty acids have maximum hypocholesteremic effects and found mainly in fish and vegetable oils.Of the fatty acids listed,linolenic acid is omega 3,linoleic and arachidonic acid is omega 6 and Oleic acid is omega 9. Ref: Heyland D.K., McClave S.A. (2005). Chapter 11. Nutrition in the Critically Ill. In J.B. Hall...
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Study of small intestine by barium infused through a Nasojejunal tube is called as
[ "Barium meal", "Barium meal follow through", "Barium enema", "Enteroclysis" ]
D
Enteroclysis : Barium introduced directly into the small intestine gives excellent visualisation by challenging the distensibility of intestinal loops, thereby making it easier to identify the presence of morphological abnormalities. Barium swallow is the contrast study from oral cavity upto the fundus of the stomach.B...
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Hexokinase is a
[ "Transferase", "Reductase", "Oxidoreductase", "Oxidase" ]
A
The International Union of Biochemistry (IUB) name of hexokinase is ATP:D-hexose 6-phosphotransferase E.C. 2.7.1.1. This name identifies hexokinaseas a member of class 2 (transferases), subclass 7 (transfer of a phosphoryl group), sub-subclass 1 (alcohol is the phosphoryl acceptor), and "hexose-6" indicates that the al...
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All are true about cytomegalovirus except:
[ "May be transmitted from pregnant mother to foetus", "Type 5 Human herpes virus", "Lymphocyte enlargement", "Cause congenital diseases" ]
C
Ans: c. Lymphocyte enlargement Cytomegalovirus (Human Herpes Virus Type 5)It is cytomegalic (not lymphoproliferative, which occur in HHV4, 6 & 7)Characterized by enlargement of infected cellsCongenital infection- Intrauterine infection leads to fetal death or cytomegalic inclusion disease of newborn which is often fata...
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The cyst is `deroofed' and the surrounding periosteum sutured to the margins of the cyst wall in
[ "Decortication", "Marsupialisation", "Saucerization", "Enucleation" ]
B
null
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Anakinra is a -
[ "IL - 1 antagonist", "IL - 2 antagonist", "IL - 6 antagonist", "IL - 10 antagonist" ]
A
Ans. is 'a' i.e., IL-1 antagonisto Anakinra is an IL-1 antagonist.o It is used for some rare syndromes dependent on IL-1 production :Neonatal - onset inflammatory diseaseMuckle - Wells syndromeFamilial cold urticariaSystemic juvenile - onset inflammatory arthritisRA
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For greatest retention of the porcelain veneer, the coping design should be
[ "Convex with undercuts", "Convex with no undercuts", "Convex with sharp angles", "Concave on facial surface" ]
B
null
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Drug not to be given in ischemic heart disease is:
[ "Atenolol", "ACE inhibitor", "Isoproterenol", "Streptokinase" ]
C
Ans. (C) Isoproterenol(Ref: KDT 8/e p585)Isoproterenol is a b adrenergic agonist and is C/I in IHD as it can increase myocardial oxygen demand by causing tachycardia.
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Drug of choice for malignant neuroleptic syndrome:
[ "Danazol", "Dantrolene", "Propranolol", "Diazepam" ]
B
Ans. B. DantroleneMalignant neuroleptic syndrome is type of Extrapyramidal side effect seen with antipsychotic drugs. It is characterized by hyperthermia, rigidity and altered mental state. It is usually treated by Dantrolene which causes muscle relaxation. Bromocriptine is also indicated for this condition.
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All of the following statement about a normal subject in the erect position are true EXCEPT
[ "Alveoli at the apex of the lung are less compliant that those at the base", "Airway resistance is greater at the apex than at the base", "More gas exchange occurs at the base of the lungs than at the apex", "The ventilation/ perfusion ratio (VA/Qc) is lowest at the base of the lung" ]
B
When the thorax is in the erect Position, the pressure generated by the right ventricle is not sufficient to perfuse apical alveoli to the same extent as it perfuses alveoli at the base of the lungs. Approximately IS times more blood flows through the capillaries at the base than at the apex. In addition, while erect, ...
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Tim dependent killing and prolonged post antibiotic effect is seen with
[ "Fluoroquinolone", "Beta lactams", "Clindamycin", "Erythromycin" ]
B
Ref Katzung 13th/879 Long post antibiotic effect is shown by most of the drugs against gram positive bacteria but few drugs have long PAE against gram negative bacteria Clindamycin and erythromycin are static6 drugs that exhibit time dependent inhibitory activity Fluroquinolone follow concentratn dependent killing
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Labile cells are also known as intermitotic cells because of its characteristics. All of the following are labile cells, EXCEPT:
[ "Skin", "Hepatocytes", "Bone marrow", "Gut mucosa" ]
B
Labile Cells (Intermitotic Cells):Labile cells normally divide actively throughout life to replace cells that are being continually lost from the body. They have a sho G0 (resting, or intermitotic) phase. Continued loss of mature cells of a given tissue is a continuous stimulus for resting cells to enter the mitotic ce...
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DOC for listeria meningitis:
[ "Ampicillin", "Cefotaxime", "Cefotriaxone", "Ciprofloxacin" ]
A
Ans. is 'a' i.e., Ampicillin Treatment of listeria infectiono The antibiotic of choice for listeria infection is ampicillin or penicillin G.Antibiotic regimens for listeria infection||||First line regimensPenicillin allergic patientsAlternative drugso Ampicillin or Penicillin is the drug of choiceo Trimethoprim sulpham...
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Which of the following enzyme uses citrate in fatty acid synthesis?
[ "Aconitase", "Citrate synthase", "Malic enzyme", "ATP citrate lyase" ]
B
Reference: Harpers illustrated biochemistry 30th edition
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The superficial inguinal ring is a defect in-
[ "Transversalis fascia", "Internal oblique", "External oblique", "External oblique aponeurosis" ]
D
null
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The following is used for testing absorption in intestine -
[ "Xylose", "Sucrose", "Fructose", "Maltose" ]
A
D-xylose absorption test is used to check how well your intestines are absorbing a simple sugar called D-xylose. From the results of the test, your doctor can infer how well your body is absorbing nutrients. D-xylose is a simple sugar that occurs naturally in many plant foods. Ref Davidson edition23rd pg 822
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Which of the following is the effect of dobutamine?(irrelevant)
[ "Increase in hea rate", "Increase in cardiac output", "Increase in BP", "Increase in plasma volume" ]
D
Dobutamine is used to treat acute but potentially reversible hea failure, such as which occurs during cardiac surgery or in cases of septic or cardiogenic shock, on the basis of its positive inotropic action.Dobutamine can be used in cases of congestive hea failure to increase cardiac output. Refer kDT 6/e
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A 19 years old young girl with previous history of repeated pain over medial canthus and chronic use of nasal decongestants, presented with abrupt onset of fever with chills and rigor, diplopia on lateral gaze, moderate proptosis and chemosis. On examination optic disc is congested. Most likely diagnosis is:
[ "Cavernous sinus thrombosis", "Orbital cellulitis", "Acute ethmoidal sinusitis", "Orbital apex syndrome" ]
A
Ans. Cavernous sinus thrombosis
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Infectious pa of chlamydia is -
[ "Elementary body", "KP body", "Reticulate body", "None" ]
A
Ans. is `a' i.e., Elementary body
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All the following can be a cause for obstruction of after coming head of breech Except:
[ "Hydrocephalus", "Placenta previa", "Incomplete dilatation", "Extended head." ]
B
Ans. b. (Placenta previa). (Ref. Dutta Obstetrics 5th ed. 402)BREECH PRESENTATION# Most common type is complete breech in multipara and frank breech (70%) in primi.# Prematurity is the commonest cause.# Other causes are uterine malformations (recurrent breech) and hydrocephalus.# Denominator--sacrum# Commonest position...
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To capture palatal root, the X-ray film should be placed
[ "At the median raphe of the palate", "At a 15 degree angle to the tooth", "As close to the tooth", "On the opposite side of the midline" ]
D
null
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What is used to prevent exposure in operation theatre-
[ "Wooden paition", "Lead gown", "Nickle gown", "Iron gown" ]
B
Park's textbook of preventive and social medicine 23rd edition. * Effective protective measures include proper use of lead shields and lead rubber aprons.
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Ramucircumab is used in the treatment of :
[ "Psoriasis", "Non small cell carcinoma of lungs", "Ascites", "Severe asthma" ]
B
Ramucircumab is a monoclonal antibody aginst VEGFR-2 used in the treatment of Non small cell carcinoma of lungs , gastric carcinoma & colorectal carcinoma.
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Which of the following is not true about Japanese encephalitis?
[ "About 80% of the patients are children below 5 years of age", "In epdidemics, cases scatter with no more than 1-2 pe village", "Ove disease to unparrent cases ratio is 1:100", "Bite from infected mosquito alwasy leads to the disease" ]
D
<p> Not all individuals bitten by infected mosquitoes develop disease. Reference:Park&;s textbook of preventive and social medicine,K.Park,23rd edition,page no:286. <\p>
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Which of the following is not true of acute conjunctivitis?
[ "Vision is not affected", "Corneal infiltration", "Topical antibiotics are the mainstay of treatment", "Pupil remains unaffected" ]
C
Ans. c. Topical antibiotics are the mainstay of treatment
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Which of the following is only yeast -
[ "Candida", "Mucor", "Rhizopus", "Cryptococcus" ]
D
Based on the morphological appearance, there are four main groups of fungi: Yeast: They grow as round to oval cells that reproduce by budding, e.g. Cryptococcus neoformans and Saccharomyces. Yeast like : They exist as yeasts with pseudohyphae, e.g. Candida Moulds: They grow as long branching filaments of 2-10 mm wide c...
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Splaying and Cupping of the metaphysis is seen in –
[ "Rickets", "Scurvy", "Paget's disease", "Lead poisoning" ]
A
null
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Fluorescin angiography is used to examine-
[ "Ciliary vasculature", "Retinal vasculature", "Corneal vasculature", "Conjuctival vasculature" ]
B
Fluorescin angiography used to examine: Retinal vasculature in DM retinopathy patients for neovascularization. Normal retinal vasculature on flouroscein angiography.
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A 42-year-old woman presents for laproscopic gastric bypass. She weighs 191 kg and is 165 cm tall. She has history of hypeension, diabetes mellitus, obstructive sleep apnea, and acid reflux. Because of the sleep apnea, there is concern about mild pulmonary hypeension. Which of the following agent is most likely to prod...
[ "Isoflurane", "Sevoflurane", "Desflurane", "Nitrous oxide" ]
C
Desflurane has the lowest blood:gas paition coefficient of all agents listed. In addition, desflurane has a lower fat:blood solubility, which may help in this case because of the patient's morbid obesity. Under usual circumstances, nitrous oxide could be used in combination with desflurane; however, in this situation, ...
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Herbe's pits are diagnostic of:
[ "Buphthalmos", "Chlamydial infection", "HSV infection", "Vernal catarrh" ]
B
CHLAMYDIAL CONJUNCTIVITIS: In established trachoma, there may be superior epithelial keratitis, sub epithelial keratitis, pannus, or superior limbal follicles, and ultimately the pathognomonic cicatricial remains of these follicles, known as Herbe's pits--small depressions covered by epithelium at the limbo corneal jun...
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All of the following are true regarding Tetralogy of Fallot except -
[ "Ejection systolic murmur in second intercostal space", "Single second hea sound", "Predominantly left to right shunt", "Normal jugular venous pressure" ]
C
Ans. is 'c' i.e., Predominantly left to right shunt Hemodynamics of Tetralogy of Fallot o The severity of obstruction to the right ventricular outflow determines the direction of blood flow.
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Melanocytes are present in
[ "Stratum Corneum", "Stratum Granulosum", "Stratum Basale", "Stratum Lucidium" ]
C
Melanoblasts, derived from neural crest, migrate to the epidermis and reside in the stratum basaleReference: Krishna Garg Histology; 5th edition; Page no: 113
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Tissue most sensitive to radiation is-
[ "Diaphysis", "Cartilage", "Epiphysis", "Metaphysis" ]
C
Epiphyseal plate is the most sensitive area of bone, and the site, which if irradiated, is most likely to result in growth abnormalities.
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All are seen in Thoracic outlet syndrome except ?
[ "Mass in the Neck", "Wasting of forearm muscles", "Adson's test positive", "Pallor" ]
B
Ans. is 'b' i.e., Wasting of foream muscle
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In an epidemic first to be done is -
[ "Identity the cases", "Confirm the diagnosis", "Identify The prone people", "Identify the causative factors" ]
B
verification of diagnosis is the first step in the investigation of an epidemic.it is necessary to examine all cases before arriving at a diagnosis.a clinical examination of a sample of cases may suffice.laboratary investigations can also be employed in such way that it is not delaying any of the epidemiological invest...
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Criminal responsiblity of insane is defined in:
[ "McNaughton's rule", "Curren's rule", "Durham rule", "American law institute test" ]
A
ANS. A
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