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10,001,300 | Radioimmunoassay of thyroxine and 3,3',5'-triiodothyronine (reverse T3) in human amniotic fluid. | [
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10,001,301 | Measurement of amniotic fluid iodothyronine concentrations may enable antenatal detection of fetal thyroid abnormalities; however, the delineation of normal ranges is complicated by methodological problems associated with strong and highly variable protein-binding, and specificity of antisera. Improved radioimmunoassay... | [
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10,001,302 | Preparation of creatine kinase-MM isoenzymes from canine and human tissues. | [
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10,001,303 | The assay of glucocerebrosidase activity using the natural substrata. | [
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10,001,304 | We examined eight published methods for the assay of glucocerebrosidase using the natural substrate glucocerebroside and tabulated the variable components and conditions while comparing these methods to ours. In each case assays were performed using our 8000-fold, partially purified human placental enzyme, having a pH ... | [
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10,001,305 | Argininosuccinate synthetase activity in cultured skin fibroblasts of citrullinemic patients. | [
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10,001,306 | The activities and kinetic properties of argininosuccinate synthetase in cultured skin fibroblasts of three citrullinemic patients with qualitative or quantitative abnormalities of hepatic argininosuccinate synthetase were examined. The cultured skin fibroblasts of a citrullinemic patient with a low hepatic argininosuc... | [
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10,001,307 | The roles of C-apolipoproteins in the metabolism of triglyceride-rich lipoproteins. | [
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10,001,308 | Beta-adrenoceptor blockade and recovery from hypoglycaemia in diabetic subjects: normalization after lactate and glycerol infusions. | [
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10,001,309 | 1. Previous studied have shown that non-selective beta-adrenoceptor blockade attenuates the blood glucose recovery rate after hypoglycaemia in type I diabetes. Apart from possible effects on hepatic glycogenolysis propranolol also inhibits the release of the important gluconeogenic substrates lactate and glycerol. 2. T... | [
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10,001,310 | Effect of noise on blood pressure and 'stress' hormones. | [
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10,001,311 | 1. Noise stimulation (95 dBA) for 20 min caused a significant increase in diastolic (12%, P less than 0.001) and mean arterial pressure (7%, P less than 0.001) in 15 healthy normotensive male subjects. 2. There was no significant change in systolic blood pressure or heart rate during exposure to noise. 3. Adrenaline, n... | [
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10,001,312 | Effect of acute vasopressin infusion on blood pressure and plasma angiotensin II in normotensive and DOCA-salt hypertensive rats. | [
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10,001,313 | 1. Arginine vasopressin was infused at 0.5, 2, 6, 18 or 54 ng min(-1) kg(-1) for 1 hr into normal, sham-operated and DOCA-salt hypertensive rats. Complete vasopressin/blood pressure dose-response curves were constructed from circulating plasma vasopressin concentrations measured at the end of each infusion. 2. DOCA-sal... | [
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10,001,314 | Efflux of noradrenaline from platelets in normotensive members of hypertensive families. | [
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10,001,315 | 1. Platelets have been used as a model of sympathetic neurons to study the storage of noradrenaline in normotensive individuals belonging to families with essential hypertension for at least two generations. 2. The initial efflux rate (k) of noradrenaline was determined in 44 young relatives (mean age 29.2 years), in 1... | [
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10,001,316 | Influence of the vagus nerve on changes in heart rate during sleep apnoea in man. | [
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10,001,317 | 1. The changes in heart rate surrounding a period of apnoeic asphyxia, produced by either central or obstructive sleep apnoea, are characteristically a progressive bradycardia during the apnoeic period followed by an abrupt reversal to tachycardia with resumption of lung inflation. 2. In a subject who had undergone bil... | [
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10,001,318 | Alterations in haem biosynthesis during the human menstrual cycle: studies in normal subjects and patients with latent and active acute intermittent porphyria. | [
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10,001,319 | Muscarinic acetylcholine receptors of the small intestine and pancreas of the rat: distribution and the effect of vagotomy. | [
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10,001,320 | 1. The distribution of muscarinic cholinergic receptors (mAChR), detected by atropine-inhibitable binding of [3H] quinuclidinyl benzilate, was examined in membrane fractions of pancreas, small intestinal muscle, mucosa, villi and crypts of sham-operated and vagotomized rats. 2. Specific (atropine inhibitable) [3H] quin... | [
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10,001,321 | Glucocorticoids decrease in conversion of thyroxine into 3, 5, 3'-tri-iodothyronine by isolated rat renal tubules. | [
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10,001,322 | 1. The effect of glucocorticoids on the deiodination of thyroxine (T4) to 3,5,3'-tri-iodothyronine (T3) was studied in rat renal tubules prepared by collagenase digestion. 2. In short-term (6h) experiments, cortisol and dexamethasone inhibited the conversion of T4 into T3 at concentrations of 2 X 10-4 mol/l and 2 X 10-... | [
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10,001,323 | Calcium balance in osteoporotic patients on long-term oral calcium therapy with and without sex hormones. | [
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10,001,324 | 1. The effect of a high calcium intake (1 mmol day-1 kg-1) alone or with the concomitant administration of oestradiol and testosterone derivatives was monitored by serial calcium balances in 48 patients with osteoporosis of various types. 2. On high calcium alone there was an increase (P less than 0.001) in both total ... | [
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10,001,325 | The effect of knee injury on the number of muscle fibres in the human quadriceps femoris. | [
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10,001,326 | By means of ultrasound scanning, bilateral measurements of the cross-sectional area of the quadriceps muscle groups were made in 14 young adults with unilateral thigh muscle wasting after knee injury. Needle biopsy specimens from the lateral mass of the muscle were used to estimate the myofibre cross-sectional area for... | [
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10,001,327 | Comparative effect of diuretics on renal water excretion in hyponatraemic oedematous disorders. | [
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10,001,328 | 1. The effects of intravenous chlorthiazid and frusemide on urinary osmolality were compared in 19 hyponatraemic oedematous patients. 2. Frusemide (1 mg/kg) caused production of a dilute urine (urine/plasma osmolality ratio, Uosm./Posm., 1.64-0.84, P less than 0.01) whereas chlorthiazid (10 mg/Kg) did not (Uosm./Posm, ... | [
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10,001,329 | Effect of locally applied subatmospheric pressure on subcutaneous blood flow during the course of acute myocardial infarction. | [
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10,001,330 | 1. The effect of locally applied subatmospheric pressure on subcutaneous blood flow was studied in six patients with acute myocardial infarction. 2. Blood flow was measured by the local 133Xe washout technique. 3. Application of subatmospheric pressures of -80 and -150 mmHg to the labelled area induced no vasoconstrict... | [
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10,001,331 | Sign-based short-term coding of American sign language signs and printed english words by congenitally deaf signers. | [
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10,001,332 | Illusory conjunctions in the perception of objects. | [
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10,001,333 | Postoperative pulmonary prophylaxis. Breathe deeply and read carefully. | [
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10,001,334 | Double porcine valve replacement in carcinoid heart disease. | [
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10,001,335 | Abnormal echoes in the left ventricular outflow tract caused by ruptured chordae tendineae of the mitral valve. | [
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10,001,336 | Primary chylopericardium. | [
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0.045511... |
10,001,337 | In a 23-year-old man with massive chylous pericardial effusion, oral administration of Sudan III and radio-active 131iodine-labelled triolein revealed an abnormal communication between the lymphatic system and the pericardial sac. Despite partial pericardiectomy and resection of the thoracic duct, the fluid reaccumulat... | [
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10,001,338 | Embolized disc from a Beall mitral valve prosthesis. Real-time echocardiographic identification. | [
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10,001,339 | Usefulness of two-dimensional echocardiography for detection of ventricular septal aneurysm with perforation after acute inferior myocardial infarction. | [
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10,001,340 | Idiopathic pulmonary hemorrhage. Ultrastructural and mineralogic study. | [
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10,001,341 | A nine-year-old girl was hospitalized because of hypoxemia and anemia. Antibasement-membrane antibodies were present in the serum, but there was no renal involvement suggestive of Goodpasture's glomerulonephritis. Biopsy of the lung showed pulmonary hemosiderosis. In ultrastructural analysis, no lesion of the alveolar ... | [
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0.045... |
10,001,342 | Angiographic relief of coronary artery spasm with sublingual nifedipine. | [
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0.0960914... |
10,001,343 | Unanticipated response to alpha-adrenergic blockade in pulmonary hypertension. | [
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0.07417... |
10,001,344 | Controlled trials and escape clauses. | [
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-0.04966... |
10,001,345 | Sarcoidosis in the Chinese. | [
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0.08977... |
10,001,346 | Measurement of functional residual capacity during mechanical ventilation for acute respiratory failure. A comparison between closed and an open-circuit helium dilution technique. | [
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0.08... |
10,001,347 | Regression, retardation of atherosclerosis progression, and collateral circulation. Their functional importance. | [
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0.042... |
10,001,348 | The transiency of oropharyngeal colonization with gram-negative bacilli in residents of a skilled nursing facility. | [
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0.061... |
10,001,349 | To determine the duration and persistence of gram-negative bacillary (GNB) oropharyngeal colonization over a specified period and the risk of subsequent GNB pneumonia developing in nursing home patients, we prospectively cultured for 31 weeks the oropharynges of patients in a skilled nursing facility. Over a 31-week pe... | [
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0.067039... |
10,001,350 | Coronary atherosclerosis in mitral stenosis. | [
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10,001,351 | Eighty-two patients with mitral stenosis underwent cardiac catheterization with coronary angiography. Twenty-one patients (26 percent) had coronary artery disease. Characteristics of the mitral valve area, cardiac output, pulmonary artery pressure, pulmonary vascular resistance, left ventricular end-diastolic pressure,... | [
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0.036687... |
10,001,352 | The role of isoproterenol in the preoperative evaluation of high-pressure, high-resistance ventricular septal defect. | [
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10,001,353 | The experience we describe derives from the short-term administration of isoproterenol in 15 patients with ventricular septal defect (VSD) and severe pulmonary artery hypertension (PAH). For the whole study group, mean pulmonary artery pressure (PAP) was 68.5 +/- 2.6 mm Hg, pulmonary vascular resistance (Rp) was 11.6 +... | [
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0.0373... |
10,001,354 | Pulsus paradoxus in acute myocardial infarction. | [
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0.... |
10,001,355 | Sixteen patients, admitted no later than eight hours after the onset of the first stage of acute myocardial infarction, underwent systemic, pulmonary, and pulmonary wedge pressure measurements on admission and 24 and 48 hours after the first symptoms. A decrease in systolic blood pressure during inspiration equal to or... | [
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0.096... |
10,001,356 | Preservation of active atrial transport; an important clinical consideration in cardiac pacing. | [
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0.049... |
10,001,357 | Loss or reversal of the normal sequence of atrioventricular contraction, such as occurs during ventricular pacing, can significantly reduce cardiac output. Opinions vary regarding the size of the pacemaker population that might benefit from preservation of active atrial transport during cardiac pacing. An assessment of... | [
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10,001,358 | A simple echocardiographic method to detect atrioventricular dissociation. A useful aid in the differential diagnosis of regular tachycardia with wide QRS complexes. | [
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0.1... |
10,001,359 | Regular tachycardia with wide QRS complexes may be difficult to classify as supraventricular (SVT) or ventricular (VT) without electrophysiologic studies. We felt that hemodynamic differences between VT and SVT should allow their distinction by echocardiography. In this study, we utilized high speed M-mode echocardiogr... | [
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10,001,360 | Echocardiographic diastolic flutter of the pulmonary valve in isolated patent ductus arteriosus. | [
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10,001,361 | Tetracycline pleurodesis during active pulmonary-pleural air leak for prevention of recurrent pneumothorax. | [
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0.07291... |
10,001,362 | Pleurodesis with a sclerosing agent was attempted in an animal model in which a pneumothorax with an active air leak was created. Adult rabbits had a small left thoracotomy and then a 1-cm controlled cut in the lung surface. Animals served as control, or tetracycline was administered. The chest tube was removed after t... | [
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0.129669... |
10,001,363 | Phonocardiographic characteristics of the St. Jude prosthesis in the aortic position. | [
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10,001,364 | Ventricular tachycardia "pleomorphism" induced by chest thump. | [
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10,001,365 | Roentgenogram of the month. Esophageal displacement secondary to blunt chest trauma. Traumatic transection of the descending thoracic aorta. | [
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0.... |
10,001,366 | Baker's asthma (grain-dust-induced asthma). | [
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10,001,367 | A 48-year-old black male with no underlying atopy developed asthma after working nine years at a bakery. The attacks of wheezing were preceded by nasal symptoms and usually occurred after several hours of work. Skin testing revealed reactivity to dust, molds, and wheat extracts; serum level of IgE was normal, and a RAS... | [
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10,001,368 | Computer-simulated conversion from intravenous to sustained-release oral theophylline. | [
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0.... |
10,001,369 | A computer equipped with a pharmacokinetic program was used to theoretically determine the proper time to administer the first dose of a commonly prescribed, sustained-release oral theophylline product (Theo-Dur) in patients maintained on a continuous intravenous aminophylline infusion. Four conversion methods were tes... | [
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10,001,370 | Family practice pharmacy service: part II. | [
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-... |
10,001,371 | A comparison of various types of patient instruction in the proper administration of metered inhalers. | [
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0.06637661... |
10,001,372 | The administration technique employed by 42 inpatients using metered inhalers were observed. Proper performance of the six steps recommended by the manufacturer provided the guidelines for correct administration. The degree of compliance with proper technique was defined as the number of steps correctly executed by the... | [
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0.078... |
10,001,373 | Cancerphobia--or whatever happened to red M&Ms? | [
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0.09140610694885254,
0.06271713972091675,
-0.0598... |
10,001,374 | Desipramine-induced agranulocytosis. A case report. | [
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10,001,375 | A suspected case of nitrofurantoin pneumonitis. | [
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10,001,376 | Counseling patients with chronic obstructive lung disease in the use of bronchodilator aerosols. | [
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10,001,377 | Correction to article on aspirin bioavailability. | [
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10,001,378 | Facts and figures from the U.K. | [
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10,001,379 | Interaction of metals and metallothionein. | [
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10,001,380 | Minimal role of the high concentration of hepatic metallothionein in the newborn rat in the toxicity, distribution, and excretion of cadmium. | [
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10,001,381 | Role of metallothionein in transport of heavy metals. | [
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10,001,382 | The role of metallothionein in the systemic distribution of cadmium. | [
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10,001,383 | Role of metallothionein in zinc uptake from rat jejunum. | [
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10,001,384 | Renal damage and form of cadmium in subcellular fractions. | [
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10,001,385 | Studies on toxicity of metallothionein in rat kidney epithelial cell culture. | [
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10,001,386 | The effect of dexamethasone on the kinetics of jejunal zinc uptake and metallothionein synthesis in the rat. | [
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10,001,387 | Several studies have linked hepatic metallothionein (MT) synthesis to changes in zinc metabolism in response to various forms of stress and to administration of glucocorticoid hormones. There is also some evidence that the intestinal absorption of Zn is enhanced under such conditions. The present studies were designed ... | [
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10,001,388 | Induction and degradation of metallothionein and their relation to the toxicity of cadmium. | [
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10,001,389 | Effects of hepatic disorder on the fate of cadmium in rats. | [
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10,001,390 | In order to test the possibility of metallothionein (MT) transfer from liver to kidney, experimental hepatic disorders produced by hepatotoxins were examined to study the release of MT from liver. 109Cd exposed rats were treated with carbon tetrachloride (CCl4) and the distribution of cadmium (Cd) in the body was studi... | [
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10,001,391 | Metal-binding properties of metallothionein in extracellular fluids and its role in cadmium-exposed rats. | [
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10,001,392 | Role of metallothionein in zinc metabolism. | [
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0.0609138123691082,
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10,001,393 | Turnover of metallothionein in mammalian cells. | [
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0.... |
10,001,394 | Critical concentration of cadmium estimated by studies on horse kidney metallothionein. | [
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10,001,395 | Tissue metallothioneins in rabbits chronically exposed to cadmium, with special reference to the critical concentration of cadmium in the renal cortex. | [
0.06481970101594925,
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10,001,396 | Metallothionein as a storage protein for cadmium: its toxicological implications. | [
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10,001,397 | Upon exposure to cadmium, the biosynthesis of metallothionein is increased in liver and kidneys. The protein sequesters a large fraction of the tissue cadmium, thereby making it less available for excretion. The primary function of the protein in cadmium metabolism, therefore, appears to be storage of the metal in a le... | [
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10,001,398 | Zinc and copper metabolism in neonates: role of metallothionein in growth and development in the rat. | [
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10,001,399 | Role of hepatic metallothionein during perinatal development in the rat. | [
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-0.0117... |
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