PMC_ID stringlengths 8 11 | Image_num stringclasses 399
values | Online_file_path stringlengths 20 50 ⌀ | Image_info_Cleaned stringlengths 2 20.6k | Caption_Clean stringlengths 1 10.6k ⌀ | label stringclasses 2
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PMC4797513 | Figure_4 | oa_package/bd/28/PMC4797513.tar.gz | ['At 2 and 4 weeks after balloon injury, the blood vessels from EPC-transplanted and control groups showed intimal hyperplasia, disordered and dense intimal and medial cells and narrowed lumen [].', 'Inhibition of neointimal proliferation by endothelial progenitor cell transplantation in injured carotid arteries (a) re... | Figure 4 Inhibition of neointimal proliferation by endothelial progenitor cell transplantation in injured carotid arteries (a) representative photomicrographs of hematoxylin-eosin stained histological cross-sections in transplantation group ( = 5) versus control group ( = 5) at 2 and 4 weeks after carotid injury (ori... | yes |
PMC4844704 | Figure_4 | oa_package/bf/58/PMC4844704.tar.gz | ['Morphological difference between eggs from resistant strain and susceptible strain.'] | Figure 4 Eggs from resistant strain parasites, showing morphology alterations, smaller size, and smaller lateral spines (10x); Eggs from resistant strain, in a bigger scale, showing morphology alterations, smaller size, and smaller lateral spines (40x); Eggs from susceptible strain parasites, showing normal morpho... | yes |
PMC11405035 | Figure_7 | oa_package/66/ac/PMC11405035.tar.gz | ['RT-qPCR confirmed silencing of Cas9 (Supplemental A), excluding the possibility of de novo CRISPR/Cas9 gene editing, whereas HA Western blotting confirmed ADAMTS12 expression (B).', 'In addition, catalytically active or inactive ADAMTS12 expression was validated in an in vitro digestion assay with the ADAMTS12-substr... | Figure 7 HMCN1 is a substrate of ADAMTS12 that facilitates ADAMTS12-induced migration. ( ) log FC of the top up- and downregulated proteins in ECM of WT versus -KO PDGFR cells ( = 3 per group). ( ) Western blot of lower-weight HMCN1 peptides (56 kDa) in kidneys from WT and mice after sham or UUO surgery ( = 6, W... | yes |
PMC7892740 | Figure_1 | oa_package/f4/8b/PMC7892740.tar.gz | [' 1).', 'Setup for MR imaging in treatment position for patients with pelvic tumors.', 'The coil holder in combination with the flat indexable tabletop allows for reproducible positioningFor head acquisitions intended to guide stereotactic radiosurgery (SRS), patients were positioned with stereotactic mask immobilizat... | Fig. 1 Setup for MR imaging in treatment position for patients with pelvic tumors. The leg rest and the foot rest are identical to the ones used during radiotherapy treatment delivery. The coil holder in combination with the flat indexable tabletop allows for reproducible positioning | yes |
PMC10421797 | Figure_39 | oa_package/1f/fe/PMC10421797.tar.gz | [] | Fig. 39 A 9-year-old boy with ileocecal tuberculosis. Axial ( ) and coronal ( ) contrast-enhanced computed tomography images show circumferential mural thickening involving the caecum and terminal ileum. Enlarged calcified lymph nodes are also seen on the coronal image ( ) | yes |
PMC8691626 | Figure_2 | oa_package/1f/85/PMC8691626.tar.gz | ['A fluorescence-based activity assay was used to measure the activity of CTSC where an enzyme-specific substrate (H-GR-AMC) was exposed to neutrophil lysates; the proteolytic activity of CTSC cleaves this substrate to generate free AMC, the fluorescence of which was measured over time (A).', 'Neutrophil lysates from f... | 10.1371/journal.pone.0261724.g002 | yes |
PMC8326590 | Figure_4 | oa_package/4c/8e/PMC8326590.tar.gz | ['axial T1-W (A) and T2-W (B) MRI images demonstrating left paratesticular mass (yellow arrow) with intermediate T1 signal and low T2 signal comparing to adjacent testis (red arrow).', '(Color version of figure is available online)axial (A) and sagittal (B) T1-W FAT SAT post contrast images demonstrating a low enhancin... | Fig. 4 axial T1-W (A) and T2-W (B) MRI images demonstrating left paratesticular mass (yellow arrow) with intermediate T1 signal and low T2 signal comparing to adjacent testis (red arrow). (Color version of figure is available online) | yes |
PMC8064425 | Figure_1 | oa_package/d4/bf/PMC8064425.tar.gz | ["Axial view of the non-contrast CT scan of the brainThe image showed no acute intracranial findingsCT: computed tomographyThe patient's initial laboratory investigations revealed good oxygenation with a partial pressure of oxygen (PaO2) of 95 mmHg, but a severe respiratory acidosis with a mild leukocytosis with granul... | Figure 1 Axial view of the non-contrast CT scan of the brain The image showedno acute intracranial findings CT:computed tomography | yes |
PMC10393224 | Figure_4 | oa_package/e2/40/PMC10393224.tar.gz | ['Subsequently, we also generated Ent2loxP/loxP Myosin Cre+ mice using a similar approach (17, 18) and exposed them to myocardial IRI (A).', 'We first confirmed the specific knockdown effect in Ent2 transcript (B) and protein levels (, C and D) in isolated cardiac myocytes in Ent2loxP/loxP Myosin Cre+ mouse hearts (Sup... | Figure 4 Tissue-specific deletion of is not associated with cardioprotection. ( ) Experimental set-up to study myocardial ischemia (60 minutes) and reperfusion (2 hours) injury in control (Myosin Cre ) or Myosin Cre mice. ( ) or transcript levels were measured from isolated cardiomyocytes from Myosin Cre or ... | yes |
PMC10682952 | Figure_2 | oa_package/e7/77/PMC10682952.tar.gz | ['The structure of the cTfRMAb-GDNF fusion protein is shown in A, which places the GDNF domain of the fusion protein in a dimeric configuration.', '2% ID/gram at an ID of 1 mg/kg (B, left panel).', ', 2000), is at the background level reflecting entrapment of the OX26 MAb in the blood volume of the brain in the mouse (... | Figure 2 Structure of TfRMAb-GDNF fusion protein where the mature human GDNF is fused to the carboxyl terminus of each heavy chain of the mouse/rat chimeric MAb against the mouse transferrin receptor (TfR), and designated the cTfRMAb-GDNF fusion protein. The fusion protein binds 2 receptors: the TfR at the mouse BBB t... | yes |
PMC4564453 | Figure_14 | oa_package/fd/54/PMC4564453.tar.gz | [] | Fig. 14 Case 4. Post-operative T1-weighted postcontrast MRI ( axial, coronal). There is no evidence of disease | yes |
PMC3135116 | Figure_5 | oa_package/02/dd/PMC3135116.tar.gz | ['Anecdotal examples include histoplasmosis with erythema multiforme (), and folliculitis in association with an adverse drug reaction to HAART ().', '004"/>Skin biopsy from a patient with AIDS-associated histoplasmosis and concomitant erythema multiforme.'] | Figure 5 Skin biopsy from a patient with AIDS-associated histoplasmosis and concomitant erythema multiforme. A lichenoid reaction is visible in relation to the dermoepidermal interface (a), while the dermis contains conspicuous numbers of yeasts (b), whose presence is highlighted with the aid of a Grocott stain (c). | yes |
PMC11017414 | Figure_4 | oa_package/9c/69/PMC11017414.tar.gz | [] | FIGURE 4 (A) Violin plot indicates the inflammation differences in three groups, showing the median, quartile, and kernel density estimations for the immune response score. (B, C) The relative proportion of seven major immune cells (B) and Tcell subtypes (C) in each sample. (D) Mean value for each cell subset including... | yes |
PMC3698794 | Figure_14 | oa_package/71/73/PMC3698794.tar.gz | [] | Figure 14. Clodronateliposomes abrogate aneurysm formation in AngIIinfused S3KO mice but fail to restore pristine state of elastin. A, Relative mRNA expression of MMP2, MMP9, and their respective inhibitors in vehicle and AngIIinfused WT and S3KO aortas after PBS or clodronateliposome treatment (n=3 per group; triplica... | yes |
PMC9734605 | Figure_2 | oa_package/2a/ae/PMC9734605.tar.gz | [' 2).', '8 cm prevascular lymph node was seen on axial and sagittal viewsOn presentation, the patient was asymptomatic.'] | Fig. 2 Contrast enhanced CT of the chest was performed using thin section reconstructions. The patient was given intravenous contrast with iopamidol. A 1.8cm prevascular lymph node was seen on axial and sagittal views | yes |
PMC9520570 | Figure_5 | oa_package/64/1c/PMC9520570.tar.gz | ['A shows that the NIAAA binge model caused liver injury demonstrated by a significant elevation in ALT levels, although ALT levels were 5-fold lower than those observed with the intragastric alcohol feeding.', 'Liver steatosis was also observed with the NIAAA binge model (A), but generally at lower levels than observe... | FIGURE 5 Effect of other alcohol feeding models on hepatic LRP1 and APP levels. The effect of the NIAAA binge model on liver injury and steatosis , in addition to LRP1 and APP expression in the liver . ALT, H&E histology (200 magnification), and immunoblotting of mice liver occurred following NIAAA binge model (6week... | yes |
PMC4456368 | Figure_7 | oa_package/fb/e2/PMC4456368.tar.gz | ['Ultrastructural differences of VICs in DMEM and fibroblast mediaBy electron microscopy, VICs in DMEM showed abundant myofilaments in their cytoplasm together with an incomplete basal lamina and membranous pinocytotic vesicles (A).', 'VICs in fibroblast media (B) showed ultrastructural features similar to the native V... | 10.1371/journal.pone.0127844.g007 | yes |
PMC4237202 | Figure_2 | oa_package/51/00/PMC4237202.tar.gz | ['We compared fly lines that express the various ataxin-3 transgenes at similar mRNA levels, according to quantitative RT-PCR (figure 2A).', 'As shown in figure 2B, K-Null ataxin-3 protein does not accumulate compared to WT or K-117 ataxin-3.', 'Mutating UbS2 does not abrogate the catalytic activity of ataxin-323 or af... | Figure 2 Lysine-less ataxin-3 does not accumulate in A) Selection of transgenic fly lines that express similar levels of ataxin-3 variants. Quantitative RT-PCR results from whole flies expressing the versions of UAS-ataxin-3 noted in the panel. At least 5 flies were used per genotype per experiment. Driver was sqh-G... | yes |
PMC11401631 | Figure_5 | oa_package/f5/1e/PMC11401631.tar.gz | ['The blue arrow points to tumor cells, and the black arrow points to benign colonic epitheliumVimentin immunohistochemistry(A,B) Vimentin shows diffuse, strong cytoplasmic positivity in tumor cellsS100 immunohistochemistry(A,B) Diffuse strong cytoplasmic and nuclear positivity in tumor cellsHMB-45 immunohistochemistry... | Figure 5 Vimentin immunohistochemistry (A,B) Vimentin shows diffuse, strong cytoplasmic positivity in tumor cells | yes |
PMC3297754 | Figure_4 | oa_package/92/c0/PMC3297754.tar.gz | [' 4).', 'c After 9 months it was reduced in size, partially calcified (arrow) and became elastic (score 1; arrowhead)\nThe results of the elastograms in relation to the lesion shape are shown in Table 4.', ' 4).'] | Fig. 4 Ultrasound showed a subcapsular oval-shaped hypoechoic pseudonodule ( ) and an adjacent rounded hyperechoic spot in a patient with recent scrotal trauma. At RTE the entire lesion and its surrounding area were blue ( ), indicating a score 5 appearance that usually indicates suspected neoplasm. Considering the s... | yes |
PMC8678227 | Figure_1 | oa_package/41/5d/PMC8678227.tar.gz | ['The experience of European pulmonary pathologistsVirchows Arch2020477359723264284231MenterTHaslbauerJDNienholdRSavicSHopferHDeigendeschNPostmortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dys... | Fig. 1 Histological vascular and gross pulmonary vascular findings in SARS-CoV-2 positive autopsies. Images demonstrate severe grade of vascular changes (larger involved areas and high number of foci) ( ), images show mild grade morphological changes (smaller or only scattered areas involved) ( ). Numerous ( ) and only... | yes |
PMC10539697 | Figure_8 | oa_package/9d/42/PMC10539697.tar.gz | ['TOF normalizes the activated STAT signaling in injured spinal cord and ex vivo microglia under inflammatory conditions.'] | Figure 8 TOF normalizes the activated STAT signaling in injured spinal cord and microglia under inflammatory conditions. Western blot analysis performed for p-STAT1, STAT1, p-STAT3 and STAT3 expression in spinal cord obtained on day 7 post-injury. Western blot analysis of p-STAT1, STAT1, p-STAT3 and STAT3 express... | yes |
PMC5041422 | Figure_3 | oa_package/a4/be/PMC5041422.tar.gz | [] | Figure 3 Axial, coronal, and sagittal Tc-methylene diphosphonate single-photon emission computed tomography/computed tomography fusion images demonstrate focal increased activity (arrows) within the right C2 lamina | yes |
PMC3813448 | Figure_2 | oa_package/c3/51/PMC3813448.tar.gz | ['Stimulation of AMPAR led to a time-dependent loss of mature APP, clearly detected at 20 min, reaching a maximum at 3 h and maintained for up to 24 h, although there was some indication of a partial recovery in APP levels at the longest time point (A and 2B).', 'The increase in -CTFs was maintained above basal level f... | 10.1371/journal.pone.0078155.g002 | yes |
PMC11502597 | Figure_9 | oa_package/6a/f5/PMC11502597.tar.gz | [' 9).', 'Abb.', 'Die sp ter entstandene untere Bruchlinie (roter Pfeil) endet (gr ne Umkreisung) an der fr her entstandenen oberen Bruchlinie (gelber Pfeil)Stumpfe Gewalt gegen den RumpfForensisch relevante, stumpfe Rumpfverletzungen entstehen durch Druck- und Zugspannungen bei schweren Gewalteinwirkungen wie bspw.'] | Abb. 9 Postmortale Computertomographie (PMCT), Puppe-Regel: mehrfache stumpfe Gewalt gegen den Kopf mit Schdelfrakturen an der linken Schdelseite. Die spter entstandene untere Bruchlinie( ) endet( ) an der frher entstandenen oberen Bruchlinie( ) | yes |
PMC7213657 | Figure_6 | oa_package/ac/4d/PMC7213657.tar.gz | [] | Figure 6 Angiography from the microcatheter within the fistula, late phase Opacification of the choledocus (red arrow) and the duodenum (yellow star) | yes |
PMC3450930 | Figure_3 | oa_package/47/fa/PMC3450930.tar.gz | [] | Figure 3 Immunohistochimie: positivit diffuse cytoplasmique lanticorps anti-HMB45 | yes |
PMC11693601 | Figure_4 | oa_package/03/32/PMC11693601.tar.gz | ['After confirming stable PCSK7 knockdown, the cells were differentiated into macrophages (A).', 'Under ischemic conditions simulated by CoCl2, TNF- levels were significantly reduced in U937 PCSK7 cells, while other cytokines remained unchanged (B).', 'Furthermore, in PCSK7 knockout mice, F4/80 macrophages post-MI exhi... | Fig. 4 PCSK7 activates the TNF- signaling pathway, driving adverse remodeling post-MI. (A) PCSK7 knockdown in U937 cells was confirmed by quantitative polymerase chain reaction (qPCR) analysis. (B) Expression levels of proinflammatory cytokines (TNF-, IL-1, and IL-6) in U937 and U937 cells treated with interferon-gam... | yes |
PMC11585153 | Figure_5 | oa_package/17/be/PMC11585153.tar.gz | [' 5a) were upregulated one day after the last mTBI and continued to show increased expression 1-week post mTBI (p 0.', ' 5a).', ' 5b).', '', 'Scale bar = 50 mNeuroinflammation in the trigeminal nucleus caudalisTrigeminal nucleus caudalis showed a wide range of gene expression changes in the transcriptomic data.'] | Fig.5 Mild TBI induced gene expression of satellite glial markers in the TG. Fold change (qPCR) in gene expression of satellite glial markers (Gfap, Gja1 and Slc1a2) in the TG of mTBI mice. Bar graphs show mRNA expression on day 1 and day 8 after the last mTBI. Data ( =56/group) in the bar graph are represented as me... | yes |
PMC5810119 | Figure_1 | oa_package/09/00/PMC5810119.tar.gz | ['1).', 'a Axial black blood CMR slice at the level of the main pulmonary artery showing a large black space devoid of lung markings typical of a large pneumothorax of the left lung.', 'The 2D appearance is much less dramatic than that of panel b\n<media xlink:href="12880_2017_240_MOESM1_ESM.'] | Fig. 1 Axial black blood CMR slice at the level of the main pulmonary artery showing a large black space devoid of lung markings typical of a large pneumothorax of the left lung. Anterior coronal Black blood slice showing complete absence of lung parenchyma in the left anterior chest giving the impression of a much ... | yes |
PMC3958076 | Figure_5 | oa_package/fe/42/PMC3958076.tar.gz | ['There was some expression of LLT1 in epithelial cells in the absence of stimulation (visualized as brown DAB substrate precipitate) and significant upregulation of expression in cell monolayers stimulated with cytokines or poly(I C) ().'] | FIG 5 LLT1 protein expression in bronchial epithelial cells. BEAS-2B cells were stimulated with 10,000 U/ml IFN-, 10 ng/ml IL-1, 10 ng/ml TNF-, or 10 g/ml poly(IC) for 16 h, and immunohistochemistry was carried out for LLT1 protein expression. LLT1 expression was visualized using DAB substrate, which forms a brown prec... | yes |
PMC11099496 | Figure_3 | oa_package/ac/f7/PMC11099496.tar.gz | [] | Figure 3 Periodic acid-Schiff (PAS) staining highlights a slight increase in superficial dermal vessel wall thickening (PAS, 160x) | yes |
PMC6856777 | Figure_2 | oa_package/59/a7/PMC6856777.tar.gz | ['2), pudendal neuralgia (', '(7).'] | Fig. 2. High-resolution US shows enlargement of an hypoechoic ulnar nerve (between calipers) in a post-traumatic mononeuropathy at the level of the medial epicondyle | yes |
PMC8392426 | Figure_11 | oa_package/35/73/PMC8392426.tar.gz | [] | Figure 11 Results from the four AI models and NIH with a grayscale CT slice. Row 1 to Row 4 is four models: SegNet, VGG-SegNet, ResNet-SegNet, and NIH. | yes |
PMC9640331 | Figure_3 | oa_package/86/84/PMC9640331.tar.gz | ['\nContrast-enhanced computed tomography scan of the abdomen findings.'] | Figure 3 A: The proximal sigmoid colon was dilated. The middle colon wall was thickened. It was markedly enhanced in the arterial phase, representing the characteristics of neoplastic lesions or chronic abscesses; B: The sigmoid colon mass compressed the bladder, and the boundary between the bladder and the mass was u... | yes |
PMC10100161 | Figure_2 | oa_package/54/e8/PMC10100161.tar.gz | ['Prognostic performance of MSS in LUSC cohorts.'] | Figure 2 Prognostic performance of MSS in LUSC cohorts. Discriminatory power of MSS in (A) training cohort, (B) test cohort, (C) internal validation cohort, and (D) external validation cohort. AUC, area under the receiver operating characteristic curve. KM analysis was performed using the logrank test. LUSC, lung squam... | yes |
PMC11652124 | Figure_1 | oa_package/c1/2f/PMC11652124.tar.gz | [] | FIGURE 1 (A) Histology showing a compound melanocytic lesion with a slightly atypical architecture and many dermal melanophages (H&E). (B) A closeup view of the lesion, with nests (circle) of mildly atypical melanocytes and some pagetoid spread into the stratum granulosum (arrows). (C) SOX 10 staining highlighting the ... | yes |
PMC4139913 | Figure_4 | oa_package/b2/ca/PMC4139913.tar.gz | ['Additional images of ring hemorrhages which highlights the presence of fibrin (A), parasites (B,C), pigment (A C), rarified brain (B D), and variable-sized hemorrhages.'] | Figure 4 . All images are originally 600x, H&E. | yes |
PMC11418639 | Figure_3 | oa_package/f9/d1/PMC11418639.tar.gz | ['At the 2-month follow-up, the patient was asymptomatic, and control MRI () confirmed the absence of NCC cysts in the basal cisterns and the trigeminal nerve in a normal anatomical position.', 'FIG.'] | FIG. 3. Immediate postoperative spiral multislice tomography ( ) with a small neumoencephalus in the basal cisterns ( ), without other findings. Axial FIESTA ( )and sagittal postgadolinium T1-weighted ( ) MRI 2 months after surgery, confirming the absence of NCC cysts and a trigeminal nerve without evidence of compress... | yes |
PMC10626213 | Figure_1 | oa_package/da/0e/PMC10626213.tar.gz | ['Brain MRI images.'] | Figure 1 Brain MRI images. T2 weighted Brain MRI axial sequence demonstrating a T2 hypointense lesion (white arrow) centered in the mid- to posterior intraconal compartment of the left orbit involving the intraocular muscles near the region of the orbital apex. (A) The lesion is seen compressing the optic nerve sheath ... | yes |
PMC8319367 | Figure_2 | oa_package/0a/32/PMC8319367.tar.gz | ['Approximately 6-7 cm oval mass located in the antimesenteric border of proximal jejunum about 50 cm distal to the duodeno-jejunal flexure was seen ().', 'Intra-op findings:6 7 cm oval mass located in the antimesenteric border of proximal jejunum about 50 cm distal to the duodeno-jejunal flexure.', 'The postoperative ... | Fig. 2 Intra-op findings: 67cm oval mass located in the antimesenteric border of proximal jejunum about 50cm distal to the duodeno-jejunal flexure. | yes |
PMC11420507 | Figure_4 | oa_package/7c/a0/PMC11420507.tar.gz | ['38 mg/L (Fig 4).', 'Fig 4(A) Coronal and (B) axial views of case 2, 4 years later.'] | Fig4 Coronal and axial views of case 2, 4 years later. | yes |
PMC7750402 | Figure_1 | oa_package/81/9a/PMC7750402.tar.gz | ['0As most common treatment intralesional curettage (, , , ) was performed.', 'Radiographs of a 17 years old patient show a manifestation of chondroblastoma in the proximal humerus.'] | Fig. 1 Radiographs of a 17years old patient show a manifestation of chondroblastoma in the proximal humerus. | yes |
PMC8498107 | Figure_5 | oa_package/03/e1/PMC8498107.tar.gz | ['While the GlyR WT was nicely expressed at the cellular membrane (A, upper lane), GlyR Y252S exhibited both cell surface expression and ER retention (co-localized with calreticulin) and formed large aggregates together with gephyrin.', 'Mutants S321F and A455P were also expressed at the membrane but mainly detectable ... | FIGURE 5 Membrane expression of GlyR variants is altered in the presence of gephyrin. HEK-293 transfected with GlyR 1, eGFP-gephyrin and WT or variants (Y252S, S321F or A455P). Cellular compartment markers (GAP-43: cell membrane, calreticulin (Cal): endoplasmic reticulum) are always co-transfected (magenta). GlyR... | yes |
PMC6074050 | Figure_3 | oa_package/26/3d/PMC6074050.tar.gz | ['In the proband II:2, light microscopic analysis of the LV from the explanted heart showed myocyte hypertrophy, diffuse interstitial fibrosis, and focal replacement fibrosis (A).', 'Epicardial fat tissue infiltrated focally into the LV myocardium, especially in areas of replacement fibrosis containing clusters of dege... | FIGURE 3 Cardiac Tissue Analysis of Truncation Variant Carrier From Family DNFDC057 (II:2) Trichrome staining of the left ventricle shows subepicardial interstitial and focal replacement fibrosis and fatty infiltration in areas containing degenerating cardiac myocytes. Scale bar = 200 m. Fatty infiltration and mi... | yes |
PMC9544116 | Figure_2 | oa_package/1d/f6/PMC9544116.tar.gz | [] | FIGURE A1 Clinical images used in the study, grouped by diagnosis: Benign conditions: (1) no changes, (2) frictional keratosis, (3) fibroma, (4) geographic tongue, (5) erosive lichen planus, (6) traumatic ulcer. Potentially malignant lesions and squamous cell carcinoma, 16 diagnosed by histopathology. | yes |
PMC6588085 | Figure_1 | oa_package/98/b7/PMC6588085.tar.gz | ['Immunohistochemical detection of hAPP in corpus callosum and cortex of young and aged Tg2576 mice (tg) and wild type littermates (wt) as indicated.'] | Figure 1 Immunohistochemical detection of hAPP in corpus callosum and cortex of young and aged Tg2576 mice (tg) and wild type littermates (wt) as indicated. Immunoreactivity for hAPP is absent in wild type brain sections demonstrating the specificity of the 1D1 antibody. Although the majority of the 1D1 labeling arises... | yes |
PMC9477649 | Figure_1 | oa_package/9c/64/PMC9477649.tar.gz | ['399Selected relevant neuroimaging.'] | Figure 1 Selected relevant neuroimaging. (A) MRV on hospital day four, revealing a non-obstructing thrombus at the junction of the right transverse and sigmoid sinuses (see arrow). (B) MRV on hospital day 10 with interval progression of the thrombus in the right transverse and sigmoid sinuses without flow (see arrow). ... | yes |
PMC3015928 | Figure_3 | oa_package/17/02/PMC3015928.tar.gz | ['After contrast went through, a narrow lumen at the point of obstruction with distal decompressed bowel could be seen ().', '.'] | Figure 3. Delayed images showing narrowed duodenal lumen at the level of obstruction (large arrow) with distal decompression (small arrow). | yes |
PMC10373415 | Figure_3 | oa_package/7d/7f/PMC10373415.tar.gz | [' 3).', 'Evaluation of the presence of IA transplanted mRNA-ITGA4 transfected or control (na ve) hBM-MSCs in the rat brain subjected to focal brain damage using MRI scan assessment.', 'Reprinted from [162]Another strategy to increase the transmigration of cells into brain tissue after intravascular infusion is to modi... | Fig. 3 Evaluation of the presence of IA transplanted mRNA-ITGA4 transfected or control (nave) hBM-MSCs in the rat brain subjected to focal brain damage using MRI scan assessment. mRNA-ITGA4 transfected and control hBM-MSCs labelled with Molday ION were visible in MRI in T2 and T2* scans up to three days after transpl... | yes |
PMC2628064 | Figure_1 | oa_package/5b/00/PMC2628064.tar.gz | ['A brain MRI showed diffuse white matter and ischemic changes in bilateral deep parietal area, and a focal signal intensity increase in the left dentate nucleus of cerebellum ().', "1KleinCJBoesCJChapinJELynchCDCampeauNGDyckPJAdult polyglucosan body disease: case description of an expanding genetic and clinical syndro... | Fig. 1 Magnetic resonance imaging of the brain showed diffuse white matter ischemic changes in bilateral deep parietal area (A and B), and focal increased signal intensity at left side dentate nucleus of cerebellum (C). | yes |
PMC6906162 | Figure_1 | oa_package/44/2b/PMC6906162.tar.gz | ['The entire process of staining and image acquisition is shown in Supplementary .', ' shows a comparison between MAD (B) and CC (C).', 'We utilized the same thresholds in MAD and CC analysis, shows roughly a 3-fold increase in percent positivity using CC compared to MAD.', 'Comparison of Cellular Classification and Ma... | Figure 1 Comparison of Cellular Classification and Marker Area Detection. Immunofluorescent staining with DAPI in blue, Hoechst in red, and EF5 in green. MAD with low (yellow), medium (orange), and high (red) hypoxic areas. CC with the same overlay classification as previously used for MAD. Comparison of percen... | yes |
PMC11465996 | Figure_6 | oa_package/c6/f4/PMC11465996.tar.gz | [':\nIn Vivo toxicity assay and histological analysis after FINPs injection in rats.', 'As shown in A and B, the time-serial body weight of rat injected FINPs at various doses are presented.', 'There was no significant difference in hematological parameters between the experimental group and the control group (C E).', ... | Figure 6: toxicity assay and histological analysis after FINPs injection in rats. (a) Male rats injected with FINPs at different concentrations and saline during the 7-day experimental period. (b) Female rats injected with FINPs at different concentrations and saline during the 7-day experimental period. (c)(e) Blood... | yes |
PMC6112230 | Figure_1 | oa_package/cd/00/PMC6112230.tar.gz | ['Radiographs demonstrate the size and shape of the fibular head (), and magnetic resonance imaging may show an anomalous insertion or tearing of the biceps femoris.', 'Anteroposterior (A) and lateral (B) radiographs of the left knee showing a prominent fibular head (outlined in red).'] | Fig 1 Anteroposterior (A) and lateral (B) radiographs of the left knee showing a prominent fibular head (outlined in red). This is one etiology of snapping biceps syndrome. When the knee goes into deep flexion, the biceps tendon can subluxate over the prominence. | yes |
PMC9701876 | Figure_2 | oa_package/fc/85/PMC9701876.tar.gz | [] | FIGURE 2 Targeted treatment design for patient to reach all involved areas by nodules and inject corticosteroid efficiently | yes |
PMC4671147 | Figure_8 | oa_package/3b/8e/PMC4671147.tar.gz | ['To validate the cytokine PCR array data, we determined protein levels of CXCL16 and Spp1 in lung tissue, using ELISA, and found increased expression of these proteins in the lungs of bleomycin-treated WT mice, but not in the lungs of bleomycin-treated STC1 Tg mice ().', 'org/1999/xlink" xlink:href="srep18117-f7"/>Tra... | Figure 8 Transgenic overexpression of STC1 inhibits bleomycin-induced expression of CXCL16 and Spp1. WT or STC1 Tg mice were treated with either saline or BLM for one week. Lungs were harvested, homogenized, protein lysates were assayed for CXCL16 and Spp1 using ELISA. Bar graphs depict the means+ SEM (n=3). | yes |
PMC7578749 | Figure_4 | oa_package/6a/2f/PMC7578749.tar.gz | ['Electron microscopy revealed the abnormal morphologies of mitochondria as impaired cristae organization and the appearance of abnormal components in p32 / CD51 TNCs (s 4A and S5A), although there was no difference in the mitochondrial mass or membrane potential measured by flow cytometry with MitoTracker Green FM and... | Figure3 Mitoribosomes are Essential for CD45 Erythroid and B-Lymphoid Progenitor Differentiation (A and B) Representative flow cytometry plots of CD44 CD51 and CD44 CD51 cells among CD31/CD45/Ter119 triple-negative cells (TNCs) in enzymatically digested bone marrow. Histograms of p32 (B) expression in CD44 CD51 ... | yes |
PMC5136556 | Figure_5 | oa_package/59/4c/PMC5136556.tar.gz | ['Monocytic cells retain their viability and phagocytic activity within native A deposits ex vivo.'] | Figure 5 The incubation of monocytic cells with native A deposits in hippocampal sections obtained from aged APdE9 mice did not affect cell viability ( , = 8). Monocytic cells also retained their characteristics as phagocytes since no difference in the percentage of CD68 expressing cells ( , = 6) or the expressio... | yes |
PMC7460128 | Figure_7 | oa_package/ae/37/PMC7460128.tar.gz | ['Mild to severe nonsuppurative encephalitis mainly affects the brainstem [28,75,76,78,81,84,85,86,87] ().', 'Nonsuppurative brainstem encephalitis.'] | Figure 7 Nonsuppurative brainstem encephalitis. ( ) Dog, mild lymphohistiocytic perivascular and parenchymal infiltrates, neuron with intranuclear inclusion bodies, Cowdry type A (inset, arrow). ( ) Cat, moderate perivascular infiltration and microgliosis (arrow), H.E. (Courtesy: Clinical and Comparative Neuropathology... | yes |
PMC3843339 | Figure_8 | oa_package/a6/38/PMC3843339.tar.gz | ['(A) Basal cell carcinoma on face, seen as pigmented nodular lesion with rolled-up margins.'] | Figure 8 (A) Basal cell carcinoma on face, seen as pigmented nodular lesion with rolled-up margins. (B) HRUS shows irregular, hypoechoic, heterogeneous lesion in the dermis, with posterior shadowing and intralesional vessels on Color Doppler | yes |
PMC6190544 | Figure_13 | oa_package/3f/5d/PMC6190544.tar.gz | [] | Fig. 13 A 30-year-old woman presented with a tender right iliac fossa mass of 4months duration. The mass was fixed and hard. POCUS ( ) using a high-frequency linear probe showed matted thickened inflamed small bowel (arrowheads) and regional lymph nodes (yellow arrow). Abdominal CT scan with intravenous contrast ( ) co... | yes |
PMC6335592 | Figure_10 | oa_package/00/0c/PMC6335592.tar.gz | [] | Fig. 10 Screenshot of the planning procedure with the intra-operative, CT-based navigation. | yes |
PMC3328474 | Figure_4 | oa_package/7d/e2/PMC3328474.tar.gz | ['01; A, B).', '01; C).', '01; D), but lower concentrations (0.', 'g004Effects of trypsin pre-incubation, heparin and EGTA on the adhesion of P.'] | 10.1371/journal.pone.0034509.g004 | yes |
PMC4981304 | Figure_1 | oa_package/47/49/PMC4981304.tar.gz | ['8 underwent endovascular embolization of an initially identified gastroduodenal pseudoaneurysm (), other patients opted for regular monitoring.', 'g001Initial CT scans (patient No.'] | 10.1371/journal.pone.0161182.g001 | yes |
PMC9320164 | Figure_4 | oa_package/1f/2e/PMC9320164.tar.gz | ['In PECS II, the medial distribution increases the extent of the lateral thoracic wall block mainly supplied by the long thoracic nerve and dorsal thoracic nerve, involving the axillary fossa, subclavian region, and deltoid muscle ().', 'Ultrasound transducer positioning of the PECS I (A) and PECS II (B) blocks and so... | Figure 4 Ultrasound transducer positioning of the PECS I ( ) and PECS II ( ) blocks and sonoanatomy of the PECS blocks ( ). | yes |
PMC10221954 | Figure_4 | oa_package/32/0b/PMC10221954.tar.gz | [' shows two representative samples of annotations (yellow regions), heatmaps predicted by the unannotated two-way classifier, and the heatmap produced by the annotated three-way classifier.', 'Representative H E slides from TCGA test set and their predicted heatmaps.'] | Fig. 4 Representative H&E slides from TCGA test set and their predicted heatmaps. Left column slides along with indicated ROIs. Middle panel: Two-way unannotated classifier heatmaps. Right panel: Three-way annotated classifier heatmaps. | yes |
PMC10602148 | Figure_6 | oa_package/3e/c9/PMC10602148.tar.gz | ['We analyzed Syn immunoreactivity in DA neurons of the SNpc, labeling TH + neurons (red) and phospho-serine-129 Syn (pSer-129, green) by double immunofluorescence (A N).', '0001, A, C D O), indicating the accumulation of pathological Syn in individual DA neurons.', '0001, B, F H O).', 'We did not detect pSer129 Syn im... | Figure 6 Treatment with 2a protects DA neurons and rescues Syn accumulation in the SNpc of AAV-A53T-Syn injected mice: A-N) Immunofluorescence in representative SN sections following double labeling of TH-positive neurons (red) and phospho-Ser129 Syn (pSer-129, green) in AAV-A53T-Syn injected mice (n=78 mice per group)... | yes |
PMC6946346 | Figure_5 | oa_package/46/12/PMC6946346.tar.gz | ['A 26-cm polycystic ovarian mass with areas containing mucin (white arrows).'] | Figure 5 A 26-cm polycystic ovarian mass with areas containing mucin (white arrows). | yes |
PMC11059464 | Figure_11 | oa_package/4a/eb/PMC11059464.tar.gz | [] | Figure 11. Schematization of the structures of the epidermis, dermis and hypodermis at the level of the nasolabial line. The connective structure appeared different at different depths. The structure of the upper lip was described in . At the level of the cheek, superficially the connective fibers were oriented parall... | yes |
PMC8698479 | Figure_4 | oa_package/62/45/PMC8698479.tar.gz | ['Twenty-four hours after exposure, disturbance of stereocilial morphology was observed mainly in outer hair cells located in the regions coding the frequencies from 4 to 16 kHz that matched the changes in the DPOAE (C,D), compared to a normal appearance of the hair cell bundles in control unexposed cochleae (A,B).', '... | Figure 4 Alteration of the OHC stereocilia A, C and E: Representative scanning electron microscopy from different coding regions of cochleae (68 kHz, 816 kHz, 1625 kHz) from control ( ), 24 h ( ), and 2 weeks ( ) after exposure. ( , , ): Higher-magnification images of representative hair bundles of the OHCs located in ... | yes |
PMC4420970 | Figure_2 | oa_package/fa/0f/PMC4420970.tar.gz | ['Examples of models of congenital defects from this study are provided in figure 2.'] | Figure2 Examples of models produced for the study: (A) patient with hypoplastic transverse aortic arch; (B) patient with aortic coarctation; (C) pulmonary anatomy of a patient being assessed for percutaneous pulmonary valve intervention, showing a hypoplastic right pulmonary artery, the left pulmonary artery and the ri... | yes |
PMC5052862 | Figure_1 | oa_package/98/c1/PMC5052862.tar.gz | ['No parenchymal lesion or bony deformity was seen in the brain ().', 'REFERENCES1JovanovicMBilateral spontaneous crystalline lens dislocation to the anterior chamber: a case reportSrp Arh Celok Lek20131418002245021012KanskiJBowlingBNischalKKPearsonAClinical ophthalmology: a systematic approachNew YorkElsevier/Saunders... | Fig. 1. Absence of acute brain parenchymal lesion upon initial computed tomography of the brain. | yes |
PMC8682942 | Figure_2 | oa_package/e8/2f/PMC8682942.tar.gz | ['Left vertical bar shows the p53 status: p53abn (red), subclonal (pink), or normal (dark blue), followed to the right by which cases of the three observers would have ordered p53 IHC (orange) or not ordered (light blue).'] | Figure 2 Left vertical bar shows the p53 status: p53abn (red), subclonal (pink), or normal (dark blue), followed to the right by which cases of the three observers would have ordered p53 IHC (orange) or not ordered (light blue). Note the single p53 abnormal case where IHC was not ordered. The first column illustrates p... | yes |
PMC9038983 | Figure_13 | oa_package/cd/62/PMC9038983.tar.gz | [] | Fig. 13 Standardised sampling biopsy map | yes |
PMC6614110 | Figure_3 | oa_package/76/a6/PMC6614110.tar.gz | ['A repeat CT pulmonary angiogram showed interval growth of the pseudoaneurysm and significant necrotic areas of the right lower lung ().', 'Repeat CT angiography showing interval growth of R lower lobe pseudoaneurysm.', 'Ultrasound of chest showing pseudoaneurysm of right lower lobe segmental pulmonary artery with int... | Fig. 3 Repeat CT angiography showing interval growth of R lower lobe pseudoaneurysm. | yes |
PMC6820961 | Figure_1 | oa_package/46/74/PMC6820961.tar.gz | ['1a) as well as uneven bladder wall thickening with bladder diverticulum (', '1b and c).', '1d) was detected after the CT image had been analysed carefully, but it was hard to distinguish its origin.', 'a Bilateral hydronephrosis.', 'd A round vague shadow near the bladder outlet\na The enlarged median lobe of the pro... | Fig. 1 Bilateral hydronephrosis. and Uneven bladder wall thickening with bladder diverticulum. A round vague shadow near the bladder outlet | yes |
PMC9902637 | Figure_3 | oa_package/52/02/PMC9902637.tar.gz | ['However, a postoperative chest radiograph revealed that manual repositioning of the Perm catheter was incomplete and the tip remained looped ().', '.'] | Fig. 3. Postoperative chest radiograph showing intraoperative manual repositioning of Perm catheter had resulted in looping of the catheter tip (black arrow). | yes |
PMC4593232 | Figure_2 | oa_package/2a/d8/PMC4593232.tar.gz | [' 2a).', ' 2B, patients with AA genotype at rs10953316 showed low MUC17 levels in their endometrium, patients with GA genotype showed moderate levels, and strong staining could be found in patients with GG genotype.', 'Influence of rs10953316 SNP on MUC17 mRNA structure and protein expression.', 'Specific staining can... | Fig. 2 Influence of rs10953316 SNP on MUC17 mRNA structure and protein expression. ( ) Partial mRNA structure of wild-type and rs10953316 SNP in were predicted by MaxExpect. Symbol *indicates the reference allele G and minor allele A sites of the rs10953316 SNP. ( ) Immunohistochemistry against MUC17 was performed on... | yes |
PMC10413550 | Figure_1 | oa_package/ea/9e/PMC10413550.tar.gz | [] | Figure1 Preoperative coronal MRI of precontrast T2WI , precontrast T1WI , and enhanced T1WI . Postoperative coronal MRI of precontrast T2WI and precontrast T1WI . | yes |
PMC5582693 | Figure_11 | oa_package/11/46/PMC5582693.tar.gz | [] | Figure 11. Ultrasound of the normal adductor tendon (arrow) insertion onto the pubic tubercle (P) in the long axis. Note the muscle bellies of the adductor longus (L) and brevis (B). | yes |
PMC11570109 | Figure_2 | oa_package/66/98/PMC11570109.tar.gz | ['An abdominal MRI was performed to characterize the hepatic lesions: one lesion was consistent with HCC and the second was metastatic from mucinous which was visible previously on imaging at the time of diagnosis of colon cancer ().', 'Two segment II hepatic lesions: the larger lesion is consistent with clear cell var... | Figure 2 Two segment II hepatic lesions: the larger lesion is consistent with clear cell variant hepatocellular carcinoma and the second, more cranial lesion, is likely metastasis from a mucinous adenocarcinoma. | yes |
PMC10525881 | Figure_6 | oa_package/06/37/PMC10525881.tar.gz | ['[9] and below).', 'Anti-VEGF reclosed the barrier relaxed with VEGF (A) to a greater extent than RS (A).', 'Anti-VEGF had no effect on the TNF -relaxed barrier (B), whereas RS completely reclosed it (B).', 'Permeability driven by the combination of TNF and VEGF was largely insensitive to anti-VEGF (C), whereas RS par... | Figure 6 Anti-VEGF reverses only VEGF-mediated barrier relaxation. Same as , except aflibercept vehicle or aflibercept was used instead of RS. Barriers were relaxed with either ( ) 100 ng/mL VEGF, ( ) 50 ng/mL TNF, or ( ) 100 ng/mL VEGF and 50 ng/mL TNF for 8 h before the addition of either aflibercept vehicle or afli... | yes |
PMC2270292 | Figure_6 | oa_package/56/95/PMC2270292.tar.gz | ['Muc2 protein was also decreased in intestinal extracts of both Winnie and Eeyore, consistent with decreased production and/or decreased stability of secreted Muc2 (A).', 'Altered Muc2 Protein Expression in Mice with Muc2 Mutations(A) Muc2 proteins from wild-type, Winnie, and Eeyore intestinal extracts were reduced an... | Figure 6 Altered Muc2 Protein Expression in Mice with Mutations (A) Muc2 proteins from wild-type, , and intestinal extracts were reduced and separated by agarose gel electrophoresis and detected by Western blotting with the mM2.2 antibody. Note the reduced intensity and the altered electrophoretic migration in the... | yes |
PMC6920437 | Figure_1 | oa_package/8a/4c/PMC6920437.tar.gz | ['0-cm hemorrhagic mass in the left temporo-parietal region with surrounding moderate vasogenic edema with mass effect on the left lateral ventricle [A].', 'This was better characterized by subsequent MRI [C], showing its hemorrhagic nature as well as multiple other sub-centimeter cerebral metastases.', 'Abdominal CT s... | Fig. 1 Patient imaging. | yes |
PMC9755302 | Figure_5 | oa_package/f1/15/PMC9755302.tar.gz | ['Urine cytology, cystoscopy, and surgical pathologyUrine samples for cytology were collected prior to cystoscopy and were directly sent to the pathology department in the same institution.'] | Figure 5 Magnetic resonance images of the extravesical tissue-invasive bladder cancer ( ) T2-weighted image in the left posterolateral aspect of the bladder wall showing a bladder cancer invading underneath the hypointense detrusor lining to the extravesical fat tissue. ( ) Dynamic contrast-enhanced image showing the e... | yes |
PMC9691811 | Figure_2 | oa_package/c4/a3/PMC9691811.tar.gz | ['Thyroid ultrasonography was done next, which revealed a general heterogeneous echotexture with parenchymal hypoechogenicity consistent with thyroiditis (figure 2).', 'Thyroid ultrasound scan revealing a gland with heterogeneous echotexture with diffuse hypo-echogenicity in bilateral lobes consistent with thyroiditis.... | Figure 2 Thyroid ultrasound scan revealing a gland with heterogeneous echotexture with diffuse hypo-echogenicity in bilateral lobes consistent with thyroiditis. | yes |
PMC7433935 | Figure_5 | oa_package/52/07/PMC7433935.tar.gz | ['Similar to height, width of the septa was measured at five different points and the final average of the five values was considered and documented [].'] | Figure 5 Measurement of the width of septa in five different areas | yes |
PMC4651348 | Figure_13 | oa_package/e4/fe/PMC4651348.tar.gz | [] | 10.1371/journal.pone.0141357.g013 | yes |
PMC5557531 | Figure_1 | oa_package/5c/5e/PMC5557531.tar.gz | ['1).', '1a), the AUC values lie between 0.', '1b), the AUC values lie between 0.', 'Receiver-operator characteristic (ROC) curves for a HBV and b HCV summarising the six models under consideration for improving prediction for imbalanced data.', 'The models are: Downsize = simple downsizing; Downsize RF = simple downsi... | Fig. 1 Receiver-operator characteristic (ROC) curves for HBV and HCV summarising the six models under consideration for improving prediction for imbalanced data. The models are: Downsize=simple downsizing; Downsize RF=simple downsizing with random forest variable selection; MDS=multiple downsizing; MDS RF=multiple ... | yes |
PMC3781448 | Figure_4 | oa_package/93/4a/PMC3781448.tar.gz | ['Both NKX6 1 (A and B) and NKX2 2 (', '4D and E) proteins and mRNA (C and F, respectively) were severely affected in HFS monkeys.', 'Islets with the fewest number of -cells had greatly diminished nuclear NKX6 1 expression, with a gradient of decreased expression of NKX6 1 in -cells of different HFS monkeys (A, bottom ... | FIG. 4. Decreased nuclear expression of NKX61, NKX22, and PDX1 after an HFS diet. : Immunostaining for insulin (green), glucagon (blue), and NKX61 (red) in monkeys after 24 months on the indicated diet. The islets from different HFS monkeys are shown in order of declining -cell numbers ( ); the red arrows indicate dep... | yes |
PMC4028530 | Figure_3 | oa_package/d3/c7/PMC4028530.tar.gz | ['3-cm parathyroid carcinoma with fibrous bands, numerous mitoses, nuclear pleomorphisms, and foci of capsular invasion ().', 'Histological findings.'] | Figure 3 Histological findings. (A) Lobules of parathyroid tissue are separated by fibrous bands (H&E, 40). (B) The cancer cells invading the capsule are stained blue (H&E, 40). (C) Capsular invasion of malignant cells (H&E, 400). (D) Several highly mitotic cells in a high-power field (H&E, 400). | yes |
PMC5442854 | Figure_7 | oa_package/51/b6/PMC5442854.tar.gz | [' 7).', 'A simultaneous video recording reveals the position of the hand-piece in relation to the specimen and the generated spectra and demonstrates good correlation with the recognition software compared to macroscopic findings\nIntraoperative iKnife - proof of principleThe iKnife was used during the entire surgical... | Fig. 7 Ex-vivo validation case study. An electrosurgical hand-piece was moved through the mastectomy specimen in mode from normal breast tissue, into tumour and out through normal tissue. A simultaneous video recording reveals the position of the hand-piece in relation to the specimen and the generated spectra and de... | yes |
PMC3152345 | Figure_6 | oa_package/c9/79/PMC3152345.tar.gz | ['We incubated GST-SC35 with Dyrk1A in vitro and found that GST-SC35, but not GST, was phosphorylated by Dyrk1A in an enzyme concentration-dependent manner (A and B).', '.', 'We found that Dyrk1A, but not Dyrk1AK188R, a dead enzyme, suppressed SC35 s activity to promote tau exon 10 inclusion (C).', 'We observed that tr... | Figure 6. Dyrk1A phosphorylates SC35 and suppresses SC35 promoted tau exon 10 inclusion. ) autoradiography of SC35 phosphorylation by Dyrk1A . Recombinant GST-SC35 was incubated with various concentrations of Dyrk1A indicated above each lane for 30min at 30C and separated by SDSPAGE and visualized with Coomassie blue... | yes |
PMC3502138 | Figure_5 | oa_package/19/66/PMC3502138.tar.gz | ['Axon profiles being myelinated by oligodendrocytes.'] | Figure 5 ( ) Oligodendrocytes encircling and myelinating axon profiles were frequently noticed in the CC (arrow). Scale bar corresponds to 250 nm. ( ) The number of axonal profiles being myelinated in the CC was identical in all four groups ( =0.063). Each dot denotes the total number in one animal. The horizontal bar... | yes |
PMC11465996 | Figure_5 | oa_package/c6/f4/PMC11465996.tar.gz | [':FINPs enhanced NIR-PAM and OCT imaging in CNV model rats.'] | Figure 5: FINPs enhanced NIR-PAM and OCT imaging in CNV model rats. (a)(d) OCT, VIS-PAM, pre-NIR-PAM, and post-NIR-PAM and B-scan image of rat fundus with nanoparticle injection. (e) The NIR-PAM signal amplitudes were enhanced 236.6% from 0.363 (a.u.) to 0.859 (a.u.) at 3minafter injection. (f) ImageJ software to qua... | yes |
PMC8354305 | Figure_10 | oa_package/6d/66/PMC8354305.tar.gz | [] | Fig. 10 ad Microscopic sections of the corpus callosum genu. a H&E section of destructive hemorrhagic white matter lesion. b H&E section with white matter pallor adjacent to hemorrhagic lesion with GFAP immunoreactive reactive astrocytes evenly distributed in the white matter (inset) c CD68 immunostaining highlights a ... | yes |
PMC5476467 | Figure_3 | oa_package/e0/c2/PMC5476467.tar.gz | ['Respiration triggered 1H MRS was carried out by means of the Stimulated Echo Acquisition Method (STEAM) with outer volume suppression and a voxel volume of approximately 10 mm3 (placed in the cortex and hippocampus, see A).', '3ImmunohistochemistryIn general, brain tissue of wt mice (A, upper left panel) were free of... | Fig. 3 (A) Representative immunohistochemical images (scale bar 20m) of -amyloid-plaques (upper panels), of NeuN positive neurons (middle panels) and of GFAP positive glial cells (lower panels) in the entorhinal cortex of wild type (wt, left panels) and of transgenic (tg, right panels) mouse. (B and C) Quantitative ana... | yes |
PMC8463659 | Figure_2 | oa_package/0e/48/PMC8463659.tar.gz | ['A shows that miR-20b-5p has significantly lower expression in DepC (p 0.', 'B shows that miR-191-5p is significantly lower in DepTBI (p 0.', 'DepC, and C shows that miR-132-3p is significantly increased in DepC (p 0.'] | FIGURE 2 Distribution of Cq Values for Representative MiRNAs in Each Group. Box plots show the distribution of the Cq values for representative miRNAs differentially expressed with respect to ComC in . The plots show that miR-20b-5p is significantly altered in the DepC and DepTBI groups miR-191-5p is significantly... | yes |
PMC6315112 | Figure_2 | oa_package/5d/1e/PMC6315112.tar.gz | ['We discovered that expression of HttQ128 from the GMR driver induces augmented levels of FlowerLoseB in the adult brain, contrary to the non-pathogenic form, HttQ0 (s 2A and 2B).', 'Surprisingly, levels of FlowerLoseB did not change with ectopic expression of the Parkinson-related peptides -SynA30P and -SynWT (s 2E a... | Figure1 Expression of Amyloid-42 in the Nervous System Generates Suboptimal Neurons that Upregulate and (A) Schematic illustrating neuronal fitness comparison. Neurons express ubiquitously Flower orFlower at their cellular membrane, but external insults such as a traumatic injury or failing to establish synaptic... | yes |
PMC9763194 | Figure_5 | oa_package/08/52/PMC9763194.tar.gz | ['We observed that BMAA induced an increased expression of toll-like receptor (TLR) 4 in primary mesencephalic neurons (figure 5A B).', '53 We also observed NF- B activation after BMAA treatment (figure 5C) and the expected increase in pro-IL-1 levels (figure 5A, D).', 'Caspase 1 that cleaves pro-IL-1 was also found to... | Figure 5 - -methylamino-L-alanine (BMAA) activates brain neuronal innate immunity and . Primary mesencephalic neuronal cultures from naive mice were treated with 1M CCCP for 2hours and 3mM BMAA for 48hours. (A) Representative immunoblot for toll-like receptor (TLR)4 and pro-interleukin (IL)-1 levels. Blots were re-p... | yes |
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