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ART002133700 | oai_dc | Curious Journey to the New Textbook of Penile Augmentation: Informed Text Briefing | Curious Journey to the New Textbook of Penile Augmentation: Informed Text Briefing | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박남철(부산대학교)"
] | 비뇨기과학 | null | kci_detailed_000251.xml | ||||
ART002133701 | oai_dc | Testosterone Replacement Therapy and Cardiovascular Risk: A Review | Testosterone Replacement Therapy and Cardiovascular Risk: A Review | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Giovanni Corona(Maggiore-Bellaria Hospital); Giulia Rastrelli(University of Florence); Elisa Maseroli(University of Florence); Alessandra Sforza(Maggiore-Bellaria Hospital); Mario Maggi(University of Florence)"
] | Recent reports in the scientific and lay press have suggested that testosterone (T) replacement therapy (TRT) is likely to increase cardiovascular (CV) risk. In a final report released in 2015, the Food and Drug Administration (FDA) cautioned that prescribing T products is approved only for men who have low T levels due to primary or secondary hypogonadism resulting from problems within the testis, pituitary, or hypothalamus (e.g., genetic problems or damage from surgery, chemotherapy, or infection). In this report, the FDA emphasized that the benefits and safety of T medications have not been established for the treatment of low T levels due to aging, even if a man's symptoms seem to be related to low T. In this paper, we reviewed the available evidence on the association between TRT and CV risk. In particular, data from randomized controlled studies and information derived from observational and pharmacoepidemiological investigations were scrutinized. The data meta-analyzed here do not support any causal role between TRT and adverse CV events. This is especially true when hypogonadism is properly diagnosed and replacement therapy is correctly performed. Elevated hematocrit represents the most common adverse event related to TRT. Hence, it is important to monitor hematocrit at regular intervals in T-treated subjects in order to avoid potentially serious adverse events. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133690 | oai_dc | Nonsurgical Interventions for Peyronie’s Disease: Update as of 2016 | Nonsurgical Interventions for Peyronie’s Disease: Update as of 2016 | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Gregory A Joice(Johns Hopkins University School of Medicine); Arthur L Burnett(Johns Hopkins University School of Medicine)"
] | Peyronie’s disease (PD) is a debilitating condition of the penis that leads to significant pain, erectile dysfunction, and emotional distress in men. PD is likely underreported due to lack of knowledge of the disease and the absence of well-established available treatments. Surgical treatment can lead to sustained improvements, but is often associated with penile shortening and places the patient at risk for perioperative morbidity. Nonsurgical management has been studied for several years as an alternative to surgery for men with PD. Currently, much of the data on nonsurgical management is conflicting, with only one treatment that has been recently approved by the US Food and Drug Administration. Significant effort has been devoted to advancing non-surgical treatments for PD that can be implemented outside of the operating room. This review aims to describe the research behind current nonsurgical therapies for PD and to highlight the recent advances that have been made within the last three years. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133691 | oai_dc | Postprostatectomy Erectile Dysfunction: A Review | Postprostatectomy Erectile Dysfunction: A Review | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Paolo Capogrosso(Università Vita-Salute San Raffaele); Andrea Salonia(Università Vita-Salute San Raffaele); Alberto Briganti(Università Vita-Salute San Raffaele); Francesco Montorsi(Università Vita-Salute San Raffaele)"
] | In the current era of the early diagnosis of prostate cancer (PCa) and the development of minimally invasive surgical techniques, erectile dysfunction (ED) represents an important issue, with up to 68% of patients who undergo radical prostatectomy (RP) complaining of postoperative erectile function (EF) impairment. In this context, it is crucial to comprehensively consider all factors possibly associated with the prevention of post-RP ED throughout the entire clinical management of PCa patients. A careful assessment of both oncological and functional baseline characteristics should be carried out for each patient preoperatively. Baseline EF, together with age and the overall burden of comorbidities, has been strongly associated with the chance of post-RP EF recovery. With this goal in mind, internationally validated psychometric instruments are preferable for ensuring proper baseline EF evaluations, and questionnaires should be administered at the proper time before surgery. Careful preoperative counselling is also required, both to respect the patient’s wishes and to avoid false expectations regarding eventual recovery of baseline EF. The advent of robotic surgery has led to improvements in the knowledge of prostate surgical anatomy, as reflected by the formal redefinition of nerve-sparing techniques. Overall, comparative studies have shown significantly better EF outcomes for robotic RP than for open techniques, although data from prospective trials have not always been consistent. Preclinical data and several prospective randomized trials have demonstrated the value of treating patients with oral phosphodiesterase 5 inhibitors (PDE5is) after surgery, with the concomitant potential benefit of early re-oxygenation of the erectile tissue, which appears to be crucial for avoiding the eventual penile structural changes that are associated with postoperative neuropraxia and ultimately result in severe ED. For patients who do not properly respond to PDE5is, proper counselling regarding intracavernous treatment should be considered, along with the further possibility of surgical treatment for ED involving the implantation of a penile prosthesis. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133692 | oai_dc | Modifying Risk Factors in the Management of Erectile Dysfunction: A Review | Modifying Risk Factors in the Management of Erectile Dysfunction: A Review | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Kenneth J DeLay(Tulane University School of Medicine); Nora Haney(Tulane University School of Medicine); Wayne JG Hellstrom(Tulane University School of Medicine)"
] | Erectile dysfunction (ED) is prevalent among men and its presence is often an indicator of systemic disease. Risk factors for ED include cardiovascular disease, hypertension, diabetes mellitus (DM), tobacco use, hyperlipidemia, hypogonadism, lower urinary tract symptoms, metabolic syndrome, and depression. Addressing the modifiable risk factors frequently improves a patient’s overall health and increases lifespan. The literature suggests that smoking cessation, treatment of hyperlipidemia, and increasing physical activity will improve erectile function in many patients. How the treatment of DM, depression, and hypogonadism impacts erectile function is less clear. Clinicians need to be aware that certain antihypertensive agents can adversely impact erectile function. The treatment of men with ED needs to address the underlying risk factors to ameliorate the disease process. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133693 | oai_dc | Clinical Outcomes of Varicocele Repair in Infertile Men: A Review | Clinical Outcomes of Varicocele Repair in Infertile Men: A Review | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Koji Chiba(Kobe University Graduate School of Medicine); Masato Fujisawa(Kobe University Graduate School of Medicine)"
] | Varicoceles are a major cause of impaired spermatogenesis and the most common correctable cause of male infertility. They are found in approximately 40% of men with primary infertility and 80% of men with secondary infertility, although they also occur in 12% of men with normal semen parameters. The presence of a varicocele does not always affect spermatogenesis, as it has been reported that only 20% of men with documented varicoceles suffer fertility problems. However, varicocele repair appears to have beneficial effects in men with impaired semen parameters and palpable varicoceles. Currently, the main procedures employed for varicocele repair are microsurgical subinguinal or inguinal varicocelectomy, laparoscopic varicocelectomy, and radiological percutaneous embolization. Microsurgical varicocelectomy appears to be the optimal treatment in most cases, whereas the other procedures are useful only in specific cases. After treatment, it typically takes 3 to 6 months for patients’ semen parameters to improve; thus, other therapies, including assisted reproductive technology, should be considered if infertility persists after this interval, especially in older couples. Controversies still remain regarding how varicoceles in certain subgroups, such as adolescents or men with azoospermia, should be treated. Due to their relatively high prevalence rate among the general population, varicoceles can occur concomitantly with other conditions that cause impaired spermatogenesis. Further studies are necessary in order to identify the patients who are most likely to benefit from treatment. In this review, we sought to summarize the issues currently associated with varicocele treatment in infertile men. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133694 | oai_dc | A Systematic Review and Meta-Analysis of Functional Outcomes and Complications Following the Photoselective Vaporization of the Prostate and Monopolar Transurethral Resection of the Prostate | A Systematic Review and Meta-Analysis of Functional Outcomes and Complications Following the Photoselective Vaporization of the Prostate and Monopolar Transurethral Resection of the Prostate | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Dong Hyuk Kang(Severance Hospital); 조강수(Gangnam Severance Hospital); 함원식(Severance Hospital); 최영득(Severance Hospital); Joo Yong Lee(Severance Hospital)"
] | Purpose: To perform a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing monopolar transurethral resection of the prostate (MTURP) and photoselective vaporization of the prostate (PVP) in order to provide the most up-to-date and reliable recommendations possible. Materials and Methods: Relevant RCTs were identified from electronic databases for meta-analysis of the surgical outcomes and complications of MTURP and PVP. Meta-analytical comparisons were made using qualitative and quantitative syntheses. The outcome variables are presented as odds ratios with 95% confidence intervals (CIs). Results: In total, 11 articles were included in this comparative analysis of PVP versus MTURP. Most of the recently published studies exhibited low risk in terms of quality assessment. MTURP was superior to PVP regarding operative time; however, with regard to catheterization and hospitalization time, the mean differences were −1.39 (95% CI=−1.83∼−0.95, p＜0.001) and −2.21 (95% CI=−2.73∼−1.69, p＜0.001), respectively, in favor of PVP. PVP was superior to MTURP with regard to transfusion rate and clot retention, but no statistically significant differences were found with regard to acute urinary retention and urinary tract infection. The long-term complications of bladder neck contracture and urethral stricture showed no statistically significant differences between PVP and MTURP. Long-term functional outcomes, including the International Prostate Symptom Score and maximum flow rate, likewise did not display statistically significant differences between PVP and MTURP. Conclusions: Based on our findings, we believe that PVP should be considered as an alternative surgical procedure for treating male lower urinary tract symptoms secondary to benign prostatic hyperplasia. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133695 | oai_dc | The Effect of Tumor-Prostate Ratio on Biochemical Recurrence after Radical Prostatectomy | The Effect of Tumor-Prostate Ratio on Biochemical Recurrence after Radical Prostatectomy | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Sung Yong Cho(Inje University College of Medicine); 최영득(Yonsei University College of Medicine)"
] | Purpose: Prostate tumor volume calculated after surgery using pathologic tissue has been shown to be an independent risk factor for biochemical recurrence. Nonetheless, prostate size varies among individuals, regardless of the presence or absence of cancer. We assumed to be lower margin positive rate in the surgical operation, when the prostate volume is larger and the tumor lesion is same. Thus, we defined the tumor-prostate ratio in the ratio of tumor volume to prostate volume. In order to compensate the prostate tumor volume, the effect of tumor-prostate ratio on biochemical recurrence was examined.Materials and Methods: This study included 251 patients who underwent open retropubic radical prostatectomy for prostate cancer in a single hospital. We analyzed the effects of tumor volume and tumor-prostate ratio, as well as the effects of known risk factors for biochemical recurrence, on the duration of disease-free survival.Results: In the univariate analysis, the risk factors that significantly impacted disease-free survival time were found to be a prostate-specific antigen level ≥10 ng/mL, a tumor volume ≥5 mL, tumor-prostate ratio ≥10%, tumor capsular invasion, lymph node invasion, positive surgical margins, and seminal vesicle invasion. In the multivariate analysis performed to evaluate the risk factors found to be significant in the univariate analysis, positive surgical margins (hazard ratio=3.066) and a tumor density ≥10% (hazard ratio=1.991) were shown to be significant risk factors for biochemical recurrence.Conclusions: Tumor-prostate ratio, rather than tumor volume, should be regarded as a significant risk factor for biochemical recurrence. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827268 | oai_dc | Urologist’s Practice Patterns Including Surgical Treatment in the Management of Premature Ejaculation: A Korean Nationwide Survey | Urologist’s Practice Patterns Including Surgical Treatment in the Management of Premature Ejaculation: A Korean Nationwide Survey | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"양대열(한림대학교); 고경태(한림대학교); 이원기(한림대학교); 박현준(부산대학교); 이성원(성균관대학교); 문기학(영남대학교); 김세웅(가톨릭대학교); 김수웅(서울대학교); 조강수(연세대학교); 문두건(고려대학교); 민권식(인제대학교); 양상국(건국대학교); 손환철(서울대학교); 박광성(전남대학교)"
] | Purpose: According to previous studies, the prevalence of premature ejaculation (PE) in Korea ranges from 11.3% to 33%. However, the actual practice patterns in managing patients with PE is not well known. In this study, we have endeavored to determine how contemporary urologists in Korea manage patients with PE.Materials and Methods: The e-mailing list was obtained from the Korean Urological Association Registry of Physicians. A specifically designed questionnaire was e-mailed to the 2,421 urologists in Korea from May 2012 to August 2012. Results: Urologists in Korea diagnosed PE using various criteria: the definition of the International Society for Sexual Medicine (63.4%), Diagnostic and Statistical Manual of Mental Disorders (43.8%), International Statistical Classification of Disease, 10th edition (61.7%), or perceptional self-diagnosis by the patient himself (23.5%). A brief self-administered questionnaire, the Premature Ejaculation Diagnostic Tool, was used by only 42.5% of the urologists. Selective-serotonin reuptake inhibitor (SSRI) therapy was the main treatment modality (91.5%) for PE patients. 40.2% of the urologists used phosphodiesterase type 5 inhibitors, 47.6% behavior therapy, and 53.7% local anesthetics. Further, 286 (54.3%) urologists managed PE patients with a surgical modality such as selective dorsal neurotomy (SDN).Conclusions: A majority of Korean urologists diagnose PE by a multidimensional approach using various diagnostic tools. Most urologists believe that medical treatment with an SSRI is effective in the management of PE. At the same time, surgical treatment such as SDN also investigated as one of major treatment modality despite the lack of scientific evidence. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827263 | oai_dc | Urinary Tract Symptoms (LUTS) Secondary to Benign Prostatic Hyperplasia (BPH) and LUTS/BPH with Erectile Dysfunction in Asian Men: A Systematic Review Focusing on Tadalafil | Urinary Tract Symptoms (LUTS) Secondary to Benign Prostatic Hyperplasia (BPH) and LUTS/BPH with Erectile Dysfunction in Asian Men: A Systematic Review Focusing on Tadalafil | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박현준(부산대학교); Ji Eon Joanne Won(Eli Lilly and Company, Indianapolis, IN, Raleigh, NC, USA); Sebastian Sorsaburu(Eli Lilly and Company, Indianapolis, IN, Raleigh, NC, USA); Paul David Rivera(INC Research); 이승욱(한양대학교)"
] | This review assesses lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) with or without erectile dysfunction (ED) and related therapies focusing on tadalafil. A literature search was obtained and reviewed for the epidemiology, treatment therapies, pathophysiology, and efficacy and safety of phosphodiesterase type 5 inhibitor (PDE5i) tadalafil in patients with LUTS/BPH. Approximately 42% of men aged 51 to 60 years have BPH. Approximately 90% of men aged 45 to 80 years have LUTS. Occurrence of LUTS increases with age for almost all racial/ethnic groups (range, 32% to 56%) with prevalence of LUTS highest among Hispanic men, then Blacks, Caucasians, and Asians. There is an independent relationship with LUTS/BPH and ED, with approximately 70% of men with LUTS/BPH having ED with severity of one disease often correlating with the other. The European Urological Association guidelines include the use of the PDE5i tadalafil. Tadalafil is the only therapy recommended for treatment of co-existing BPH and ED, while other therapies have unwanted ED side effects. The mode of action of tadalafil may involve different areas of the lower urinary tract such as smooth muscle cell relaxation in the bladder neck, prostate, and urethra, but there may also be resulting modulation of the afferent nerve activity. Tadalafil (5 mg) in Asian men with LUTS/BPH, similar to global studies, is efficacious and safe. Tadalafil (5 mg) improves co-existing LUTS/BPH and ED, independently. Men with LUTS/BPH likely also have ED. Asian men with LUTS/BPH have similar incidence rates, co-existing ED, comorbid diseases, and risks as non-Asian men. Tadalafil can improve co-existing LUTS/BPH and ED. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827257 | oai_dc | The Non-Surgical Treatment of Peyronie Disease: 2013 Update | The Non-Surgical Treatment of Peyronie Disease: 2013 Update | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Eric James Shaw(Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA); Gregory Clyde Mitchell(Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA); Ronny B. Tan(Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA); Premsant Sa... | Peyronie disease is a common cause of penile deformity and sexual dysfunction. Although surgery is regarded as the definitive management for this condition, there are many medical and minimally invasive therapies available, with widely varying efficacy reported in the literature. The purpose of this review is to describe the current state-of-the-art for each of the most commonly used as well as several developing non-surgical treatments. Further, we hope to offer perspectives that will aid practitioners in deciding among these treatments that are either already in use or have the potential to be used as alternatives to surgery in the management of this frustrating disease. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827265 | oai_dc | Can the Mean Platelet Volume Be a Risk Factor for Vasculogenic Erectile Dysfunction? | Can the Mean Platelet Volume Be a Risk Factor for Vasculogenic Erectile Dysfunction? | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Halil Ciftci(Harrran University); ErcanYeni(Harrran University); Mehmet Demir(Department of Urology, Harran University Faculty of Medicine, Sanliurfa); Ismail Yagmur(Department of Urology, Harran University Faculty of Medicine, Sanliurfa); Kemal Gümüş(Department of Urology, Harran University Faculty of Medicine, S... | Purpose: The mean platelet volume (MPV) is a marker of the platelet activity and is reported to increase in vascular diseases. We aimed to investigate the association between MPV and vasculogenic erectile dysfunction (ED). Materials and Methods: MPV and platelet (PLT) levels were measured in 50 cases of ED and 40 healthy controls. The diagnosis of vasculogenic ED was based on a detailed sexual history, physical examination, laboratory assessment, and color Doppler ultrasonography. The results are given as mean±standard deviation of the mean. Results: The mean ages of the patient and the control groups were 53.70±12.39 years (range 24∼77 years) and 53.85±9.5 years (range 30∼73 years), respectively (p=0.947). The MPV and PLT values were significantly higher in the patients with ED than those of the controls (7.49±1.4), (6.85±1.2), (262.97±68), (252.89±82) respectively, p＜0.001). However, the MPV values were not statistically significantly different in the patients with severe ED according to the International Index of Erectile Function than in those with mild ED, p＞0.05), and there was no correlation between MPV and either age of patients (p=0.905) or duration of ED (p=0.583). Conclusions: The platelet count and MPV was detected to be increased in patients with vasculogenic ED. This finding suggests a role for platelets in the pathogenesis of vascular complications and that the MPV would be useful in monitoring disease progression. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827271 | oai_dc | The Effect of Anthocyanin on the Prostate in an Andropause Animal Model: Rapid Prostatic Cell Death by Apoptosis Is Partially Prevented by Anthocyanin Supplementation | The Effect of Anthocyanin on the Prostate in an Andropause Animal Model: Rapid Prostatic Cell Death by Apoptosis Is Partially Prevented by Anthocyanin Supplementation | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"장훈(가톨릭대학교); 배웅진(가톨릭대학교(성의교정)); 김수진(가톨릭대학교); 육성모(가톨릭대학교); 한동석(가톨릭대학교); 하유신(가톨릭대학교); 황성연(Korea BioMedical Science Institute); 윤신희(가톨릭대학교); Zhiping Wang(Department of Urology, Second Hospital of Lanzhou University, Lanzhou, China); 김세웅(가톨릭대학교)"
] | Purpose: To evaluate the anti-apoptotic effect of the antioxidant reaction of anthocyanin on the prostate in an andropause animal model.Materials and Methods: Sprague-Dawley rats were divided into three groups (n=12 in each): control (Group I), andropause (Group II), andropause treated with anthocyanin (Group III). For induction of andropause, Group II and III underwent bilateral orchiectomy. Group III was treated with daily oral anthocyanin (160 mg/kg) for 8 weeks. After 8 weeks, the rats were sacrificed and their blood and prostates were examined pathohistologically and evaluated for oxidative stress and apoptosis. Oxidative stress was assessed by the activity of superoxide dismutase (SOD) and apoptosis in the prostate was identified by terminal deoxyribonucleotidyl transferase-mediated dUTP-digoxigenin nick end-labelling assay.Results: Group II showed markedly increased activity of SOD in serum over that observed in Group I, whereas the rats in Group III showed reduced oxidative stress compared to Group II. Despite no significant differences in prostate weight between Group II and III (p=0.078), the apoptotic index was significantly greater in Group II than Group I, and was significantly lesser in Group III than Group II.Conclusions: We suggest that the oxidative stress caused by low testosterone may be another inducer of apoptosis, and this apoptosis may partly contribute to the overall apoptosis of the prostate in the andropause animal model. Therefore, anthocyanin supplementation may contribute to preventing excessively rapid cell death by apoptosis in the prostate in an animal model of andropause. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827279 | oai_dc | A Case of Duplicated Vas Deferens Found Incidentally during Varicocelectomy | A Case of Duplicated Vas Deferens Found Incidentally during Varicocelectomy | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이준녕(경북대학교병원); 김범수(경북대학교); 김현태(경북대학교); 정성광(경북대학교)"
] | Duplication of the vas deferens is a very rare congenital anomaly in which two vasa deferentia coexist within the spermatic cord. Duplication of the vas deferens can be found during herniorrhaphy, vasectomy, and varicocelectomy performed on the spermatic cord or around the spermatic cord. However, it is estimated that the incidence of duplication of the vas deferens is under-reported and under-recognized. Unless anomalies of the vas deferens such as duplication of the vas deferens are recognized by surgeons, it will be difficult to reduce vas deferens injuries and achieve a satisfactory surgical outcome. In addition, care should be taken in cases of duplication of the vas deferens because it can be complicated by non-testicular genitourinary anomalies. We report a case of duplication of the vas deferens discovered during routine varicocelectomy. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827267 | oai_dc | Dichotomous Estimation of Prostate Volume: A Diagnostic Study of the Accuracy of the Digital Rectal Examination | Dichotomous Estimation of Prostate Volume: A Diagnostic Study of the Accuracy of the Digital Rectal Examination | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Michael Z. Su(Sydney Adventist Hospital Clinical School, University of Sydney, Sydney, NSW, Australia); Daniel Lenaghan(Sydney Adventist Hospital Clinical School, University of Sydney, Sydney, NSW, Australia); Henry H. Woo(Sydney Adventist Hospital Clinical School, University of Sydney, Sydney, NSW, Australia)"
] | Purpose: To assess the diagnostic reliability of a dichotomous digital rectal examination (DRE) tool in assessing prostate volume (PV) compared to gold-standard transrectal ultrasound (TRUS) volume measurement.Materials and Methods: Male patients presenting to a single tertiary referral centre urology practice requiring TRUS were prospectively recruited between January 2010 and August 2011. Size was estimated by DRE immediately prior to TRUS measurement. DRE measurements were classed into four groups: ＜30 mL , 30 to 49 mL, 50 to 99 mL and ＞100 mL. The primary outcomes were sensitivity, specificity, and the positive and negative likelihood ratios for a 30 mL cut-off. Results: Three hundred and three patients were recruited to the study. The median age of the study group was 64.9 years. On TRUS analysis, 244 patients had a PV larger than 30 mL and 139 of them, larger than 50 mL. The median PV was 47 mL with a median International Prostate Symptom Score of 10 and prostatic specific antigen (PSA) of 5.7. When analysed for the ability to identify a gland larger than 30 mL, DRE had a high sensitivity and low negative likelihood ratio. The median PSA level (ng/L) for prostates measured by DRE with a 30 mL cut-off was significantly different with higher median PSA values for volumes larger than 30 mL. Conclusions: DRE is a reliable tool for dichotomous assessment of prostatic volumes above 30 mL and 50 mL. These results illustrate the value of re-examining the role of categorical DRE estimations in benign prostatic hyperplasia patients. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827269 | oai_dc | The Association between Type of Work and Insulin Resistance and the Metabolic Syndrome in Middle-Aged Korean Men: Results from the Korean National Health and Nutrition Examination Survey IV (2007∼2009) | The Association between Type of Work and Insulin Resistance and the Metabolic Syndrome in Middle-Aged Korean Men: Results from the Korean National Health and Nutrition Examination Survey IV (2007∼2009) | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"권춘식(가톨릭관동대학교); 이준호(국립경찰병원)"
] | Purpose: Type of work might be related to insulin resistance and the metabolic syndrome (MetS). However, scant data are available. We performed this study to investigate whether the prevalence of MetS and insulin resistance differed according to occupation in middle-aged men.Materials and Methods: In all, 2,348 men in their 40s∼50s who had participated in the Korean National Health and Nutrition Examination Survey IV were included and were classified into two groups according to the type of work (manual worker vs. non-manual worker). Diagnosis of MetS required satisfying three or more of the National Cholesterol Education Program-Adult Treatment Panel III criteria. Fasting insulin, the glucose/insulin ratio (G/I ratio), and the homeostasis model assessment of insulin resistance (HOMA-IR) were used to estimate the insulin resistance. We used the Mann-Whitney test, χ2 tests, multiple linear regression test, and logistic regression analyses to examine the relationships.Results: Age was significantly higher in the manual worker group. Body mass index was significantly lower in the manual worker group. Rates of current smoking and frequent drinking were higher in the manual worker group. In terms of surrogate markers of insulin resistance, the age-adjusted mean of fasting insulin, G/I ratio, and HOMA-IR indicated that lower insulin resistance was significantly related to manual work. After adjusting for age and other confounding factors, non-manual workers had a higher risk of the MetS than manual workers. The odds ratio in relation to MetS was significantly lower in the manual workers.Conclusions: MetS and impaired insulin resistance are significantly related to non-manual work in middle-aged Korean men. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827278 | oai_dc | An Unusual Presentation of Crossed Testicular Ectopia as an Incarcerated Inguinal Hernia | An Unusual Presentation of Crossed Testicular Ectopia as an Incarcerated Inguinal Hernia | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박윤준(단국대학교); 이길호(단국대학교)"
] | Crossed testicular ectopia (CTE) is generally defined as both testes located in the same hemiscrotum and contralateral hydrocele with the absence of a testis. However, the initial presentation of CTE in an infant as an incarcerated inguinal hernia is extremely rare. We report on a 10-month-old infant with CTE, who visited the emergency room presenting with a left incarcerated inguinal hernia. After manual reduction for an incarcerated hernia and left inguinal herniorraphy, the left testis was fixed into the left hemiscrotum and right transseptal orchiopexy was performed. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827277 | oai_dc | A Case of Fibrous Pseudotumor of the Paratesticular Region | A Case of Fibrous Pseudotumor of the Paratesticular Region | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Jyotsna Naresh Bharti(Department of Pathology, Maulana Azad Medical College, New Delhi, India); Biswajit Dey(Department of Pathology, Maulana Azad Medical College, New Delhi, India); Ashna Mittal(Department of Pathology, Maulana Azad Medical College, New Delhi, India); Prerna Arora(Department of Pathology, Maulana... | A 78-year-old male patient presented with an inguinoscrotal nodule that had lasted for 3 years. The patient reported a past medical history of hydrocele formation. The final diagnosis was fibrous pseudotumor of the paratesticular region, which was based on a histopathological examination and immunohistochemical findings. The aim of this case report is to spread awareness and recognition of neoplastic and non-neoplastic entities that occur in the paratesticular region. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827275 | oai_dc | Preliminary Report on the Safety of a New Herbal Formula and Its Effect on Sperm Quality | Preliminary Report on the Safety of a New Herbal Formula and Its Effect on Sperm Quality | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김수진(가톨릭대학교); 김미란(가톨릭대학교); 황성연((주)KMSI); 배웅진(가톨릭대학교(성의교정)); 김설(가톨릭대학교); 홍성후(가톨릭대학교); 황태곤(가톨릭대학교); Zhiping Wang(Second Hospital of Lanzhou University, Lanzhou, China); 김세웅(가톨릭대학교); 이지열(가톨릭대학교)"
] | Purpose: Male infertility is a serious problem, and its prevalence has been increasing. Therefore, we investigated the safety of a new herbal formula and its effects on sperm quality.Materials and Methods: An in vitro cytotoxicity test in TM3 Leydig cells was performed to evaluate cell viability after administration of five types of herbs separately and of a new herbal formula containing these five. An in vivo test in male mice was performed to evaluate the influence of the new herbal formula on the reproductive organs and sperm quality. After the 8- and 28-day oral administration of the new herbal formula, the weights of the reproductive organs were measured and the sperm count and motility were evaluated.Results: In the in vitro cytotoxicity test, less than 80% cell viability at concentrations of 500 mg/L and 1,000 mg/L of Rubus coreanus Miquel and Cuscuta chinensis Lam was observed. However, more than 80% cell viability was observed at all the tested concentrations of the new herbal formula. After the 8- and 28-day oral administration, there were no considerable changes in body weight. The weights of the testes, epididymis, and seminal vesicles after the 8- and 28-day oral administration were similar to those of the control. The sperm count and activity were significantly improved compared with those of the control group at 8 and 28 days after 100, 200, and 400 mg of oral administration.Conclusions: The safety of the new formula and its positive effect on the sperm quality were observed after the oral administration of the formula. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827264 | oai_dc | Low-Intensity Shock Wave Therapy and Its Application to Erectile Dysfunction | Low-Intensity Shock Wave Therapy and Its Application to Erectile Dysfunction | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Hongen Lei(Andrology Center, Department of Urology, Peking University First Hospital, Peking University,Beijing); Jing Liu(Andrology Center, Department of Urology, Peking University First Hospital, Peking University,Beijing); Huixi Li(Andrology Center, Department of Urology, Peking University First Hospital, Pekin... | Although phosphodiesterase type 5 inhibitors (PDE5Is) are a revolution in the treatment of erectile dysfunction (ED) and have been marketed since 1998, they cannot restore pathological changes in the penis. Low-energy shock wave therapy (LESWT) has been developed for treating ED, and clinical studies have shown that LESWT has the potential to affect PDE5I non-responders with ED with few adverse effects. Animal studies have shown that LESWT significantly improves penile hemodynamics and restores pathological changes in the penis of diabetic ED animal models. Although the mechanisms remain to be investigated, recent studies have reported that LESWT could partially restore corpus cavernosum fibromuscular pathological changes, endothelial dysfunction, and peripheral neuropathy. LESWT could be a novel modality for treating ED, and particularly PDE5I non-responders with organic ED, in the near future. However, further extensive evidence-based basic and clinical studies are needed. This review intends to summarize the scientific background underlying the effect of LESWT on ED. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001827273 | oai_dc | Expression of Heat Shock Protein 27 in Prostate Cancer Cell Lines According to the Extent of Malignancy and Doxazosin Treatment | Expression of Heat Shock Protein 27 in Prostate Cancer Cell Lines According to the Extent of Malignancy and Doxazosin Treatment | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이승욱(한양대학교); 이정우(한양대학교); 정재훈(한양대학교); 조정기(한양대학교)"
] | Purpose: Heat shock protein 27 (HSP27) is known as the material that plays a role in apoptosis control in tumor and cell protection including the immune response, drug tolerance, and so on. In this study, HSP27 expression according to the prostate cancer malignancy level was evaluated, and HSP27 expression was also analyzed after inducing apoptosis by doxazosin treatment of the prostate cancer cell lines.Materials and Methods: Reverse transcription polymerase chain reaction (RT-PCR) and immunofluorescence staining of the HSP27 was implemented by the culture of RWPE-1, LNCaP, androgen-independent human prostate cancer cells (PC-3), and TSU-Pr1 cell lines. Analysis was separately conducted in the control group, control vector group treated by dimethyl sulfoxide, and groups treated with 10 μM or 25 μM doxazosin. The expression of HSP27 in RT-PCR and immunofluorescence staining was observed and evaluated after conversion to numerical values. Results: In the RT-PCR results, depending on the cell type, LNCaP, TSU-Pr1 showed the highest HSP27 expression followed by PC-3, LNCaP and RWPE-1 in sequence. After doxazosin treatment, the expression detected by RT-PCR was stronger at a 25-μM doxazosin concentration compared to that at a 10-μM concentration, and the result was similar by immunofluorescence staining.Conclusions: HSP27 expression increased depending on the prostate cancer cell line. This meant that HSP27 expression was related to the prostate cancer malignancy level. Additionally, the higher the treatment concentration in PC-3 was, the higher the HSP27 expression was. This result showed that doxazosin induced apoptosis of prostate cancer. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001868611 | oai_dc | The Efficacy and Safety of Tadalafil 5 mg Once Daily in Korean Men with Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia: An Integrated Analysis | The Efficacy and Safety of Tadalafil 5 mg Once Daily in Korean Men with Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia: An Integrated Analysis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이성원(성균관대학교); 백재승(서울대학교); 박현준(부산대학교); Ji Eon Won(Eli Lilly Korea); Yoji Morisaki(Eli Lilly Japan K.K.); Sebastian Sorsaburu(Eli Lilly and Company); Lars Viktrup(Lilly Research Laboratories)"
] | Purpose: This post hoc integrated analysis assessed the efficacy and safety of tadalafil 5 mg once daily in a large Korean population with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH-LUTS). Materials and Methods: Individual Korean participant data were integrated from three 12-week, randomized, double-blind, placebo-controlled studies in Asian men with BPH-LUTS, wherein 177 Korean men received placebo and 177 received tadalafil 5 mg once daily. The primary objective was to compare the change from baseline to week 12 in total International Prostate Symptom Score (IPSS) after treatment with tadalafil versus placebo. Results: A significantly greater improvement (p＜0.001) in total IPSS from baseline to week 12 was observed for tadalafil compared to placebo (least squares mean: tadalafil=−5.97; placebo=−3.94 ). Total IPSS at weeks 4 and 12, IPSS voiding and storage subscores at weeks 4, 8, and 12, and IPSS quality of life index at weeks 8 and 12 were also significantly improved (p ＜0.05) for tadalafil compared to placebo. There was significant improvement (p＜0.001) in the patient global Impression of improvement responses and numerical improvement in the clinician global impression of improvement responses with tadalafil compared to placebo. There were no significant treatment differences for peak urine flow rate or postvoid residual volume . Few participants had treatment-emergent adverse events and there were no unexpected safety findings. Conclusions: This integrated analysis of three randomized, placebo-controlled Asian studies confirmed tadalafil 5 mg once daily as an efficacious and well-tolerated treatment for Korean men with BPH-LUTS. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001868609 | oai_dc | Effect of Oxidative Stress on Male Reproduction | Effect of Oxidative Stress on Male Reproduction | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Ashok Agarwal(Cleveland Clinic); Gurpriya Virk(Cleveland Clinic); Chloe Ong(Cleveland Clinic); Stefan S du Plessis(Stellenbosch University)"
] | Infertility affects approximately 15% of couples trying to conceive, and a male factor contributes to roughly half of these cases. Oxidative stress (OS) has been identified as one of the many mediators of male infertility by causing sperm dysfunction. OS is a state related to increased cellular damage triggered by oxygen and oxygen-derived free radicals known as reactive oxygen species (ROS). During this process, augmented production of ROS overwhelms the body’s antioxidant defenses. While small amounts of ROS are required for normal sperm functioning, disproportionate levels can negatively impact the quality of spermatozoa and impair their overall fertilizing capacity. OS has been identified as an area of great attention because ROS and their metabolites can attack DNA, lipids, and proteins; alter enzymatic systems; produce irreparable alterations; cause cell death; and ultimately, lead to a decline in the semen parameters associated with male infertility. This review highlights the mechanisms of ROS production, the physiological and pathophysiological roles of ROS in relation to the male reproductive system, and recent advances in diagnostic methods; it also explores the benefits of using antioxidants in a clinical setting. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001868610 | oai_dc | Mirodenafil for the Treatment of Erectile Dysfunction: A Systematic Review of the Literature | Mirodenafil for the Treatment of Erectile Dysfunction: A Systematic Review of the Literature | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박현준(부산대학교); 문경현(울산대학교); 이승욱(한양대학교); 이원기(한림대학교); 감성철(경상대학교); 이준호(국립경찰병원); 박남철(부산대학교)"
] | Phosphodiesterase type 5 (PDE5) inhibitors are the most commonly used treatment for erectile dysfunction (ED). Since the launch of sildenafil, several drugs−including mirodenafil, sildenafil citrate (sildenafil), tadalafil, vardenafil HCL (vardenafil), udenafil, and avanafil−have become available. Mirodenafil is a newly developed pyrrolopyrimidinone compound, which is a potent, reversible, and selective oral PDE5 inhibitor. Mirodenafil was launched in Korea in 2007, and an orally disintegrating film of mirodenafil was developed in 2011 for benefitting patients having difficulty in swallowing tablets. This study aimed to review the pharmacokinetic characteristic profile of mirodenafil and report evidence on its efficacy in the case of ED. In addition, we reviewed randomized controlled studies of mirodenafil’s daily administration and efficacy for lower urinary tract symptoms. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001868612 | oai_dc | Sympathetic Skin Response in Patients with Vascular Erectile Dysfunction | Sympathetic Skin Response in Patients with Vascular Erectile Dysfunction | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Mostafa Jazayeri(Shiraz University of Medical Sciences); Behrooz Kazemi(Shiraz University of Medical Sciences); Alireza Aminsharifi(Urology and Nephrology Research Center); Alireza Ashraf(Shiraz University of Medical Sciences); Mahshid Naseri(Shiraz University of Medical Sciences); Ali Nasseri(Shiraz University of... | Purpose: We aimed to investigate the utility of sympathetic skin response (SSR) test for evaluating vasculogenic erectile dysfunction (ED) which is the most common type of impotence. Materials and Methods: Men in the age group of 28 to 60 years and suffering from vasculogenic ED, as confirmed by a papaverin test and color Doppler sonography, at least for 6 months referred from our university urology department were included. We used the International Index of Erectile Function (IIEF-5) for grading severity of dysfunction and recorded the SSR of every patient from the median, tibial, and dorsal nerves of the penis. One-way analysis of variance (ANOVA), independent t-test and Pearson’s correlation coefficient were used for comparing quantitative variables, and Fisher's Exact test was used for comparing qualitative variables. The Mann-Whitney U Test and the Kruskal-Wallis test were performed for analysis of data that were not normally distributed. A p value of less than 0.05 was considered significant. Results: Forty-two patients were recruited for the study. We found a strong statistical relationship between the IIEF score and the pathologic SSR registered from every mentioned nerve. Patients with abnormal SSR had more severe ED according to IIEF score (p＜0.001). In addition, the IIEF score had a significantcorrelation with diabetes mellitus and cardiovascular disease (t-test; p＜0.05). Conclusions: Our results confirmed the presence of autonomic dysfunction in patients with vasculogenic impotence via an SSR test. We suggest evaluating the efficacy of the SSR test in patients with vascular impotence for treatment response monitoring in future studies. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001868613 | oai_dc | Testicular Biopsy Histopathology as an Indicator of Successful Restoration of Spermatogenesis after Varicocelectomy in Non-obstructive Azoospermia | Testicular Biopsy Histopathology as an Indicator of Successful Restoration of Spermatogenesis after Varicocelectomy in Non-obstructive Azoospermia | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Hamdy Abdelmawla Aboutaleb(Minoufiya University Hospitals); Eid Abdel-Rasoul Elsherif(Minoufiya University Hospitals); Mohammed Kamal Omar(Minoufiya University Hospitals); Tarek Mohammed Abdelbaky(Minoufiya University Hospitals)"
] | Purpose: We aimed to evaluate the efficacy of using testicular biopsy histopathology as an indicator of the success of loupe-assisted subinguinal varicocelectomy in non-obstructive azoospermia (NOA) patients.Materials and Methods: In a 2-year period, a prospective study was carried at Minoufiya University Hospital on 20 NOA patients with clinical bilateral varicoceles. These patients underwent loupe-assisted subinguinal varicocelectomy with simultaneous testicular biopsy. All patients were evaluated by determining their hormonal profile and performing semen analyses and scrotal Doppler and transrectal ultrasonography. Two semen analyses showing azoospermia were performed before the surgery and two semen analyses were received at 3 and 6 months post-operatively for follow-up.Results: The mean age was 29.9±6.7 years, and the mean follow-up duration was 17.3±8.3 months. We noted the restoration of spermatogenesis in six men (30% of all patients). Testicular biopsy results were as follows: hypospermatogenesis in 7 patients, maturation arrest in 3, and Sertoli cell-only syndrome in 10. The improvement in the sperm counts of these patients ranged from 3 million to 15 million/mL. Sperms were recovered in the hypospermatogenesis (6 patients, 85.5%) patients only, but other patients with testicular biopsy results of Sertoli cell-only or maturation arrest did not show any improvement in their semen parameters. Conclusions: Testicular biopsy results showed that hypospermatogenesis patients have a better chance of improvement in their semen analysis after varicocelectomy in contrast to NOA patients with Sertoli cell-only syndrome or maturation arrest. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001868614 | oai_dc | Is Semen Analysis Necessary for Varicocele Patients in Their Early 20s? | Is Semen Analysis Necessary for Varicocele Patients in Their Early 20s? | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"권춘식(가톨릭관동대학교); 이준호(국립경찰병원)"
] | Purpose: To determine whether it is necessary to analyze the semen of varicocele patients in their early 20s who are not complaining of infertility.Materials and Methods: Data was collected retrospectively from 128 men with varicocele with no complaint of infertility, but with complaints of pain/discomfort or a mass/swelling during a 4-year period beginning in January 2009. The varicocele cases were matched 4 : 1 by age to 32 hemospermia controls.Results: The median patient age was 22.0 years in the case group and 24.0 years in the control group. The median values of the percentage of normal motility, normal morphology, and density in the case group were 42.5%, 40.0%, and 51.0×106/mL, respectively. The median serum testosterone level was 4.2 ng/mL and 7.0% of the total patients had low serum testosterone levels in the case group. The number of patients with asthenospermia (17.2%), oligospermia (10.9%), and teratospermia (5.5%), and those with at least one abnormal semen parameter (19.5%) was significantly higher in the case group than the control group. The median values of the motility, morphology, and density of the case group were significantly lower than those of the control group. The multivariate analysis showed that patient characteristics (age, presence of pain, duration of symptoms, and grade of varicocele) cannot help to predict abnormal semen parameters (asthenospermia, oligospermia, teratospermia, or cases of at least 1 abnormal semen parameter) or serum testosterone levels ＜3.0 ng/mL. Conclusions: Semen analysis is required as a screening test for semen abnormalities regardless of the chief complaint in varicocele patients in their early 20s. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001868615 | oai_dc | The Incidence of Fever after Subinguinal Microsurgical Varicocelectomy | The Incidence of Fever after Subinguinal Microsurgical Varicocelectomy | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"안현수(서울대학교병원 비뇨기과); 백재승(서울대학교); 김수웅(서울대학교)"
] | Purpose: In the present study, we aimed to identify the incidence of fever in patients after subinguinal microsurgical varicocelectomy and to evaluate the clinical factors associated with the occurrence of the fever.Materials and Methods: We retrospectively reviewed the cases of patients who underwent subinguinal microsurgical varicocelectomy (group A) under spinal anesthesia. In addition, we reviewed the cases of patients who underwent microsurgical vasovasostomy under spinal anesthesia as a control group (group B). The incidence of fever in each group was compared. We investigated the clinical factors influencing the occurrence of fever in the patients of group A.Results: The incidence of fever in group A was significantly higher than that in group B (32.5% [53/163] vs. 0.4% [1/284]; p＜0.001). Clinical factors such as age, varicocele grade, weight, height, operation time, number of ligated veins, usage of immediate postoperative analgesics, presence of postoperative hematoma, and duration of hospital stay were not significantly associated with the occurrence of fever.Conclusions: We found that one-third of the patients developed transient fever after subinguinal microsurgical varicocelectomy, and therefore, this information should be provided during preoperative counseling. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001868616 | oai_dc | The Role of Imaging in the Diagnosis of Recurrence of Primary Seminal Vesicle Adenocarcinoma | The Role of Imaging in the Diagnosis of Recurrence of Primary Seminal Vesicle Adenocarcinoma | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Martina Sollini(Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia); Monica Silvotti(Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia); Massimiliano Casali(Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia); Franco Giovanardi(Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia); Alvise Zadro(Arcispedale Santa Ma... | Primary seminal vesicle (SV) adenocarcinoma is a rare tumor. A small amount of data about the role of imaging to detect tumor recurrence is available. We report the case of a 58-year-old patient with primary SV clear-cell well-differentiated adenocarcinoma. Clinical and instrumental examinations were negative for the 32 months after treatments when computed tomography scan, [18F]fluoro-D-glucose positron emission tomography/computed tomography and pelvic magnetic resonance imaging showed the appearance of a lesion in the left perineal muscle suspected for recurrence. Patient was symptomless. Cytology of the suspected lesion confirmed SV adenocarcinoma recurrence. The combined approach, using radiological and nuclear medicine techniques, seems to be effective in the follow-up of SV adenocarcinoma. Technological advances, together with awareness of this rare tumor, have the potential of improving patients outcomes not only by providing earlier detection and accurate staging, but also by detecting recurrence and thereby avoiding delays and therapeutic dilemmas. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001868617 | oai_dc | Necrosis of the Penis with Multiple Vessel Atherosclerosis | Necrosis of the Penis with Multiple Vessel Atherosclerosis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김성대(제주대학교); 허정식(제주대학교); 김영주(제주대학교)"
] | Penile necrosis is a very rare complication because of its rich collateral supply. Conservative management is apt to be ineffective; thus penectomy is usually performed. We present a case of penile necrosis and claudication of both legs with multiple atherosclerosis in a type II diabetes mellitus patient who was successfully treated with angioplasty, penoplasty, and additional intracavernous injections of prostaglandin E1. The treatment resulted in relief of the leg pain and healing of the penile ischemic lesions. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796031 | oai_dc | Risks and Benefits of Late Onset Hypogonadism Treatment: An Expert Opinion | Risks and Benefits of Late Onset Hypogonadism Treatment: An Expert Opinion | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Giovanni Corona(Maggiore-Bellaria Hospital, Bologna, Italy); Linda Vignozzi(University of Florence, Florence, Italy); Alessandra Sforza(Maggiore-Bellaria Hospital, Bologna, Italy); Mario Maggi(University of Florence, Florence, Italy)"
] | Late-onset hypogonadism (LOH) is a syndromic condition that has a well-recognized association with sexual and reproductive failure. LOH is frequently associated with chronic conditions including cardiovascular diseases (CVD), obesity, osteoporosis, HIV infection, renal failure, and obstructive pulmonary diseases. Despite this evidence, in patients with these conditions, LOH is still only rarely investigated and testosterone replacement therapy (TRT) rarely considered. In this paper, we critically reviewed the available evidence on LOH treatment focusing on possible risks and benefits. Medical therapy of LOH should be individualized depending on the etiology of the disease and the patient’s expectations. The fear of prostate cancer and the risk of erythrocytosis probably represent the main limitations of TRT in aging men. However, TRT in healthy older men in near physiological doses does not appear to incur serious adverse events, although regular monitoring of prostate-specific antigen and hematocrit levels is required. Available evidence also suggests that TRT might ameliorate central obesity and glycometabolic control in patients with metabolic syndrome and type 2 diabetes. In addition, TRT has been associated with an increase in bone mineral density in men with osteoporosis, with an improvement in lean body mass in subjects with human immunodeficiency virus infection or chronic obstructive pulmonary disease, as well as with peripheral oxygenation in patients with chronic kidney diseases. Despite this evidence, however, it should be recognized that the results of these trials were heterogeneous and limited by small sample sizes. Hence, further research is required regarding the long-term benefits and adverse effects of TRT in LOH. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796059 | oai_dc | The Surgical Procedure Is the Most Important Factor Affecting Continence Recovery after Laparoscopic Radical Prostatectomy | The Surgical Procedure Is the Most Important Factor Affecting Continence Recovery after Laparoscopic Radical Prostatectomy | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이승수(양산부산대학교병원 비뇨기과); 윤창진(부산대학교); 박현준(부산대학교); 이정주(부산대학교); 하홍구(부산대학교)"
] | Purpose: We analyzed factors associated with early recovery of continence after laparoscopic radical prostatectomy.Materials and Methods: Among 467 patients treated with laparoscopic radical prostatectomy for localized prostate cancer between 2007 and 2012, 249 patients who underwent a preoperative urodynamic study were enrolled. The patients’ age, prostate volume, preoperative serum prostate-specific antigen (PSA), Gleason score, pathologic stage, and preoperative urodynamic parameters were recorded. The preoperative membranous and prostatic urethral length on magnetic resonance image, nerve sparing technique, and type of surgical procedure (extrafascial and intrafascial) were analyzed. Patients were considered to have early recovery of continence when they needed no pad in 3 months or less after surgery. Results: Ninety-two patients were in the early recovery group and 157 were in the late recovery group. The membranous urethral lengths were 12.06±2.56 and 11.81±2.87 mm, and prostatic urethral lengths were 36.39±6.15 and 37.45±7.55 mm in each group, respectively. The membranous-posterior urethral length ratios were 0.25±0.06 and 0.24±0.06, and prostatic-posterior urethral length ratios were 0.75±0.06 and 0.76±0.06, respectively. In and of themselves, the membranous and prostatic urethral lengths were not associated with recovery duration however, the membranous-total and prostatic-total urethral length ratios were related (p=0.024 and 0.024, respectively). None of the urodynamic parameters correlated with continence recovery time. In the multivariate analysis, the type of surgical procedure (odds ratio [OR], 7.032; 95% confidence interval [CI], 2.660 to 18.590; p＜0.001) and membranous urethral length (OR, 0.845; 95% CI, 0.766 to 0.931; p=0.001) were significantly related to early recovery of continence.Conclusions: The current intrafascial surgical procedure is the most important factor affecting early recovery of continence after laparoscopic radical prostatectomy. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796057 | oai_dc | A Quality Analysis of Randomized Controlled Trials about Erectile Dysfunction | A Quality Analysis of Randomized Controlled Trials about Erectile Dysfunction | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"정재훈(한양대학교); 이정우(한양대학교); 조정기(한양대학교); 김규식(한양대학교); 이승욱(한양대학교)"
] | Purpose: A low quality clinical trial could produce errors, and these errors could, in turn, distort the results of the clinical trial. To avoid applying distorted results of trials clinically, a quality analysis of clinical trials is needed. Materials and Methods: We selected randomized controlled trials (RCTs) about erectile dysfunction (ED) conducted in Korea using Medline and KoreaMed. Quality assessment of selected RCTs was performed using three assessment tools (Jadad scales, van Tulder scale, Cochrane Collaboration Risk of Bias Tool [CCRBT]).Results: The first RCT about ED conducted in Korea was published in 2002. Since 2002, a total of 20 RCTs have been published in medical journals. Among the 20 articles, only 1 article was found to have a low risk of bias according to the CCRBT. On the Jadad scale, there were 17 high quality articles, while 19 articles were assessed as high quality by the VTS. Only 2 RCTs described the randomization method adequately. Only 1 RCT presented allocation concealment.Conclusions: A low quality clinical trial could produce errors, and these errors could, in turn, distort the results of the clinical trial. To avoid applying distorted results of trials clinically, a quality analysis of clinical trials is needed. The quality of RCTs was found to be high because almost all of the selected RCTs were double blinded studies. However, the quality of RCTs was inadequate with regard to the lack of randomization and absence of allocation concealment. Therefore, performing adequate randomization and adding a description of the appropriate concealment of allocation may improve the quality of RCTs. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796062 | oai_dc | Testosterone Deficiency with Erectile Dysfunction in Mongolian Men | Testosterone Deficiency with Erectile Dysfunction in Mongolian Men | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Nansalmaa Naidan(University of Mongolia, Ulaanbaatar, Mongolia); Oyun-Erdene Rivaad(Monos Medical Institute); Namsrai Muukhai(University of Mongolia, Ulaanbaatar, Mongolia); Munkhtsetseg Janlav(University of Mongolia, Ulaanbaatar, Mongolia)"
] | Purpose: To detect the testosterone deficiency syndrome in Mongolian men over 40 years old with erectile dysfunction (ED).Materials and Methods: Total of 309 males over 40 years of age who received medical care at the ADAM Urology and Andrology Clinic from 2010 to 2011 were included in this study. An approval from the Ethics Committee of the Ministry of Health of Mongolia was obtained, and each study participant signed a consent form at the beginning of the study. The participants were assigned to either an ED group or a control group, depending on the results of the international index of erectile function (IIEF)-5 questionnaire. The ED group was further divided into three groups (moderate, severe, and very severe) based on the level of ED. The total testosterone (TT) levels were determined in the blood serum using a competitive enzyme-linked immunesorbent assay (ELISA) analytical system UBI MagiwelTM Testosterone Quantitative test, and free testosterone (FT) calculated as described by the Vermeulen calculation. Test samples were collected between 8：00 and 11：00 am in the mornings and testosterone deficiency syndrome was diagnosed based on the International Society for the Study of the Aging Male guidelines, particularly, if TT was ≤3.46 ng/ml or free testosterone FT was ≤0.072 ng/ml.Results: ED of moderate, severe, and very severe levels was diagnosed in 199 (64.41%) out of 309 participants. There was an inverse relationship between the main IIEF-5 score and age (r=−0.380, p＜0.01). The average TT was 5.75±2.316 ng/ml and FT was 0.091±0.0084 ng/ml. Compared to the ED group, the control group had a higher TT level: 5.6440±1.177 ng/ml and 5.812±2.316 ng/ml, respectively. In the control group, the FT level was 0.061±0.0084 ng/ml, whereas it was 0.041±0.0076 ng/ml in the ED group.Conclusions: Our study showed that most of the aging males who came to the clinic had moderate to very severe ED (64.55%). The levels of TT (5.644±1.177 ng/ml) and FT (0.041±0.0036 ng/ml) were significantly lower in ED patients (p＜0.05). The testosterone deficiency syndrome was detected in 24.27% of the ED group. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796043 | oai_dc | The Anti-Inflammatory Effects of a New Herbal Formula (WSY-1075) in a Nonbacterial Prostatitis Rat Model | The Anti-Inflammatory Effects of a New Herbal Formula (WSY-1075) in a Nonbacterial Prostatitis Rat Model | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"윤병일(가톨릭관동대학교); 배웅진(가톨릭대학교(성의교정)); 김수진(가톨릭대학교); 김효신(가톨릭대학교); 하유신(가톨릭대학교); 손동완(가톨릭대학교); 황성연((주)KMSI); 김세웅(가톨릭대학교)"
] | Purpose: The aim of this study was to investigate the anti-inflammatory effects of a new herbal formula (WSY-1075) in a nonbacterial prostatitis rat model.Materials and Methods: Prostatitis was induced in male Wistar rats (n=32) by treatment with 17 beta-estradiol and dihydrotestosterone for 4 weeks. After the induction of prostatitis, the rats were randomly divided into one of four treatment groups: control (n=8), ciprofloxacin (n=8), WSY-1075 (100 mg/kg) (n=8), and WSY-1075 (400 mg/kg) (n=8). After 4 weeks of treatment, the prostatic proinflammatory cytokine (tumor necrosis factor-α, interleukin [IL]-6, and IL-8) levels and histological findings were noted.Results: The ciprofloxacin and WSY-1075 treatment groups showed significantly decreased proinflammatory cytokine levels compared with the control group. Histologically, treatment with ciprofloxacin and WSY-1075 significantly suppressed the severity of prostatitis lesions compared with those in the control group. No differences in the proinflammatory cytokine levels or histologic findings were observed with the dose dependent treatment of WSY-1075.Conclusions: The new herbal formula, WSY-1075, showed effective anti-inflammatory activities in the prostate and may be useful for the clinical treatment of nonbacterial prostatitis. Our findings suggest that WSY-1075 has a beneficial effect on the prevention and treatment of nonbacterial prostatitis. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796067 | oai_dc | Ectopic Prostate Tissue at the Bladder Dome Presenting as a Bladder Tumor | Ectopic Prostate Tissue at the Bladder Dome Presenting as a Bladder Tumor | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김재헌(순천향대학교); 진윤미(순천향의과대학부속병원); 송윤섭(순천향대학교)"
] | The presence of ectopic prostate tissue in the bladder is common, but the involvement of the bladder dome has rarely been reported. This case report describes a 72-year-old man who presented with gross painless hematuria. Cystoscopy revealed a smooth sessile mass at the dome region of the bladder. A complete transurethral resection of the mass was performed. Histopathological examination of the mass revealed the presence of benign ectopic prostatic tissue. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796024 | oai_dc | Korean Society for Sexual Medicine and Andrology (KSSMA) Guideline on Erectile Dysfunction | Korean Society for Sexual Medicine and Andrology (KSSMA) Guideline on Erectile Dysfunction | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"류지간(인하대학교); 조강수(연세대학교); 김수진(가톨릭대학교); 오경진(전남대학교병원); 감성철(경상대학교); 서경근(Urology Clinic); 신홍석(대구가톨릭대학교); 김수웅(서울대학교)"
] | In February 2011, the Korean Society for Sexual Medicine and Andrology (KSSMA) realized the necessity of developing a guideline on erectile dysfunction (ED) appropriate for the local context, and established a committee for the development of a guideline on ED. As many international guidelines based on objective evidence are available, the committee decided to adapt these guidelines for local needs instead of developing a new guideline. Considering the extensive research activities on ED in Korea, data with a high level of evidence among those reported by Korean researchers have been collected and included in the guideline development process. The latest KSSMA guideline on ED has been developed for urologists. The KSSMA hopes that this guideline will help urologists in clinical practice. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796032 | oai_dc | The Relationship between Testosterone Deficiency and Men’s Health | The Relationship between Testosterone Deficiency and Men’s Health | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Akira Tsujimura(Osaka University, Suita, Japan)"
] | Testosterone is important in the physiology of various organs and tissues. The serum testosterone concentration gradually declines as one of the processes of aging. Thus, the concept of late-onset hypogonadism has gained increasing attention in the last few years. Reported symptoms of late-onset hypogonadism are easily recognized and include diminished sexual desire and erectile quality, particularly in nocturnal erections, changes in mood with concomitant decreases in intellectual activity and spatial orientation, fatigue, depression and anger, a decrease in lean body mass with associated decreases in muscle volume and strength, a decrease in body hair and skin alterations, and decreased bone mineral density resulting in osteoporosis. Among these various symptoms, sexual dysfunction has been the most common and necessary to treat in the field of urology. It is well known that a low serum testosterone level is associated with erectile dysfunction and hypoactive sexual libido and that testosterone replacement treatment can improve these symptoms in patients with hypogonadism. Recently, in addition to sexual dysfunction, a close relationship between metabolic syndrome, characterized by central obesity, insulin resistance, dyslipidemia, and hypertension, and late-onset hypogonadism has been highlighted by several epidemiologic studies. Several randomized control trials have shown that testosterone replacement treatment significantly decreases insulin resistance in addition to its advantage for obesity. Furthermore, metabolic syndrome is one of the major risk factors for cardiovascular disease, and a low serum testosterone level is closely related to the development of atherosclerosis. Presently, it is speculated that a low serum testosterone level may increase the risk for cardiovascular disease. Thus, testosterone is a key molecule in men’s health, especially that of elderly men. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796036 | oai_dc | The Role of Androgen in the Adipose Tissue of Males | The Role of Androgen in the Adipose Tissue of Males | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이현기(서울대병원); 이주경(서울대학교); 조비룡(서울대학교)"
] | Adipose tissue, where various metabolic hormones are secreted, plays a role in metabolizing different substances including androgen. Within fat tissue, enzymes such as aromatase and aldo-keto reductase 1C are responsible for metabolizing testosterone into estrogen and 5-dihydrotestosterone into inactive metabolites. Adipose tissue can also affect the secretion of gonadotropin, which influences the formation of androgen in the testes. At the same time, androgen has an impact on the distribution and proliferation of adipose tissue. The adrenoreceptors for catecholamines, which have been proven to play an essential role in controlling lipolysis, function by being up-regulated by androgens. Furthermore, androgens regulate the activity of lipoprotein lipase, a key enzyme involved in intracellular esterification of adipose tissue. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796038 | oai_dc | Effects of Sesame Oil on the Reproductive Parameters of Diabetes Mellitus-Induced Male Rats | Effects of Sesame Oil on the Reproductive Parameters of Diabetes Mellitus-Induced Male Rats | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Zahra Abbasi(Shahid Chamran University of Ahvaz, Ahvaz, Iran); Seyed Reza Fatemi Tabatabaei(Shahid Chamran University of Ahvaz, Ahvaz, Iran); Yazdan Mazaheri(Shahid Chamran University of Ahvaz, Ahvaz, Iran); Farid Barati(Shahid Chamran University of Ahvaz, Ahvaz, Iran); Hasan Morovvati(Shahid Chamran University of... | Purpose: The purpose of the present study was to investigate the effect of sesame oil on the reproductive parameters of diabetic male Wistar rats.Materials and Methods: The adult male rats in a split plot design were divided into normal (n=10), normal 5% (n=5; 5% sesame oil enriched diet), diabetic (Streptozocin induced diabetes; n=9), diabetic 5% (n=9; 5% sesame oil enriched diet), and diabetic 10% (n=9; 10% sesame oil enriched diet) groups. Diet supplementation continued for 56 days. Results: Sesame oil supplementation did not reduce the plasma glucose concentration of rats in the diabetic groups (p＞0.05). The total spermatogonia, spermatocytes, Leydig cells/tubule, and the germ cell to Sertoli cell ratio were lower in the diabetic rats than the normal ones (p＜0.05), and with the exception of spermatogonia counts, these values improved by the addition of sesame oil to the diet (p＜0.05). The sperm progressive motility and viability were lower in the diabetic rats (p＜0.05) and sesame oil supplementation did not improve them. Incorporation of sesame oil into the diet improved the plasma testosterone concentration of the diabetic rats in a dose-dependent manner (p＜0.05).Conclusions: In summary, sesame oil supplementation improved the reproductive parameters of diabetic rats at the levels of the testicular microstructure and function, but was not effective in protecting the epididymal sperm. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001796069 | oai_dc | Intrascrotal and Extratesticular Multiple Schwannoma | Intrascrotal and Extratesticular Multiple Schwannoma | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김영주(제주대학교); 김성대(제주대학교); 허정식(제주대학교)"
] | Schwannoma, which may occur in any region of the body, is very rare in the scrotum. Schwannomas are tumors that originate from Schwann cells and, theoretically, could affect any nerve. In spite of the rich innervation of the genital area, these kinds of tumors are not common in the scrotum. A 67-year-old man visited our hospital for investigation of a 2-year episode of multiple slowly growing masses in the scrotum. Testicular tumor markers were within normal range (beta human chorionic gonadotropin ＜5 mIU, α-fetoprotein : 4.86 ng/ml). Scrotal ultrasonography revealed intrascrotal and extratesticular masses in the mid-scrotal region. Complete excision of the scrotal masses was performed. After surgery there was no testicular invasion. Histological examination of the resected specimen showed them to be schwannomas of the scrotum. We report one case of multiple schwannomas of the scrotum with a review of the literature. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763647 | oai_dc | Surgical Management for Peyronie’s Disease | Surgical Management for Peyronie’s Disease | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Robert L. Segal(Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Medical Institut); Arthur L. Burnett(Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Medical Institut)"
] | Peyronie’s disease is a common debilitating condition for both men and their partners that results in penile deformity and compromises sexual functioning. While there are a myriad of medical therapeutic options, these have not been demonstrated to correct the deformity and restore sexual function definitively. As such, surgery is the mainstay of treatment for this disease, and multiple surgical approaches may be considered depending on disease characteristics, patient co-morbidity, and findings on preoperative diagnostic testing. The purpose of this review is to highlight the different surgical approaches and different procedures within each approach, and to examine important issues for surgeons to consider for administering the best treatment that restores function while reconciling patient expectations. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763662 | oai_dc | Clinical Significance of Wnt/β-Catenin Signalling and Androgen Receptor Expression in Prostate Cancer | Clinical Significance of Wnt/β-Catenin Signalling and Androgen Receptor Expression in Prostate Cancer | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"정수진(인제대학교부속부산백병원); 오상택(국민대학교); 이근택(The Cancer Institute of New Jersey and Robert Wood Johnson Medical School); 정재일(인제대학교); 민권식(인제대학교); 윤장호(인제대학교부속부산백병원); 김완석(인제대학교); 류동수(성균관대학교); Isaac Yi Kim(Robert Wood Johnson Medical School); 강동일(인제대학교)"
] | Purpose: To investigate the relationships among the Wnt/β-catenin pathway, androgen receptor (AR), and clinicopathological factors in hormone-naïve prostate cancer.
Materials and Methods: This study was conducted with132 cases of hormone-naïve prostate cancer treated by prostatectomy and prostate needle biopsy. An immunohistochemical study using antibodies against β-catenin, matrix metalloproteinase-7 (MMP-7), and the AR was performed. For the in vitro study, PC-3, LNCaP, 22Rv1, and DU145 cell lines were used.
Results: The clinical or pathological stage ware a localized cancer in 36 patients (27.3%), locally advanced cancer in 31 (23.5%), and metastatic cancer in 65 (49.2%). We detected increased β-catenin, AR, and MMP-7 expression with a high Gleason grade, disease progression, and increasing serum prostate-specific antigen (PSA) levels (p＜0.01). In Spearman’s rank correlations, the expression of cytoplasmic β-catenin, MMP-7, and the AR were found to be significantly positively correlated. In addition, the expression of β-catenin, MMP-7, and the AR were significantly correlated with clinicopathological variables indicative of a poor prognosis. Forty-nine patients with primary androgen deprivation had short response durations from hormone therapy to PSA progression with elevated MMP-7 expression on the Kaplan-Meier curve (p=0.0036).
Conclusions: These data show that an activated Wnt/β-catenin pathway and AR expression in prostate cancer are correlated with metastasis and aggressiveness. In addition, the expression of MMP-7 protein, a target of the Wnt/β-catenin pathway, is associated with PSA progression in prostate cancer patients undergoing primary hormone therapy. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763676 | oai_dc | Effect of Transurethral Resection of the Prostate on Storage Symptoms in Patients with Benign Prostatic Hyperplasia of Less than 30 ml | Effect of Transurethral Resection of the Prostate on Storage Symptoms in Patients with Benign Prostatic Hyperplasia of Less than 30 ml | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"강유진(동국대학교); 김기호(동국대학교); 서영진(동국대학교); 이경섭(동국대학교)"
] | Purpose: Many patients with benign prostatic hyperplasia (BPH) have not only voiding symptoms but also storage symptoms. Despite the many types of treatment that have been developed for BPH, storage symptoms persist. We conducted an assessment of the efficacy of transurethral resection of the prostate (TURP) and the change in the International Prostate Symptoms Score (IPSS) storage sub-score after the procedure according to prostate size in patients with BPH.
Materials and Methods: Men aged 50 years or older who had BPH were enrolled in this study. 186 patients were divided into two groups according to prostate size measuring using transrectal ultrasonography: In group 1, prostate size was less than 30 ml (51 patients), and in group 2, prostate size was greater than 30 ml (135 patients). All of the patients underwent TURP. We examined whether the degree of change in the IPSS, voiding symptoms, storage symptoms, and quality of life (QoL) differed before and after TURP and according to prostate size.
Results: After three months of TURP, the subjects in both groups showed significant improvement in the IPSS, voiding symptoms, storage symptoms, QoL, and maximum flow rate (p＜0.05). The scores for the IPSS, voiding symptoms, storage symptoms, and QoL of group 1 and 2 after three months of TURP were 16.36, 14.25 (p=0.233), 8.21, 8.24 (p=0.980), 8.11, 5.16 (p=0.014), 2.89, and 2.10 (p=0.030), respectively.
Conclusions: TURP is an effective treatment for patients with BPH, regardless of prostate size. However, while the improvement in the storage symptoms of patients with a prostate size of less than 30 ml was not significant, it was in patients with a prostate size greater than 30 ml. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763688 | oai_dc | Stuttering Priapism in a Patient with Neurosyphilis | Stuttering Priapism in a Patient with Neurosyphilis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김종욱(고려대학교); 채지윤(고려대학교); 김진욱(고려대학교); 윤철용(고려대학교); 오미미(고려대학교); 김제종(고려대학교); 문두건(고려대학교)"
] | We recently encountered a case of stuttering priapism in a 41-year-old patient with neurosyphilis. Priapism very rarely has a neurogenic cause, and to our knowledge, priapism caused by neurosyphilis has not been reported previously in the literature. Our aim was to report this case and systematically review the related literature. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763694 | oai_dc | Multiple Intratesticular Cysts | Multiple Intratesticular Cysts | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"강성민(부산대학교); 황대성(부산대학교); 이정우(부산대학교); 천원희(부산대학교); 박남철(부산대학교); 박현준(부산대학교)"
] | Intratesticular cysts, once thought to be a rarity, are now being reported with an increasing prevalence as a result of the wider use of scrotal ultrasound scanning. Despite greater understanding of intratesticular cysts, their management remains unclear. Treatment has included enucleation and even radical orchiectomy over fear of the possibility of an associated malignancy. A more conservative approach with serial ultrasound scanning has been advocated if a clear distinction can be made between neoplastic and non-neoplastic testicular cysts. However, in view of the benign nature of such cysts, even repeated ultrasound scanning may not be necessary and may be considered over-treatment. In this study we present clinical and morphological characteristics of multiple cysts in the right testicle in a 62-year-old patient, where a slightly nodular lesion in the right testicle was detected. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763664 | oai_dc | Testosterone Replacement Alone for Testosterone Deficiency Syndrome Improves Moderate Lower Urinary Tract Symptoms: One Year Follow-Up | Testosterone Replacement Alone for Testosterone Deficiency Syndrome Improves Moderate Lower Urinary Tract Symptoms: One Year Follow-Up | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"고영휘(영남대학교); 문두건(고려대학교); 문기학(영남대학교)"
] | Purpose: To evaluate the actual impact of testosterone replacement therapy (TRT) on patients with lower urinary tract symptom (LUTS), without benign prostate hyperplasia (BPH) medication.
Materials and Methods: Two hundreds forty-six patients underwent TRT using intramuscular injection of 3 months bases injection of testosterone 100 mg undecanoate over a year. Among them, 17 patients had moderate LUTS with a maximal flow rate of at least 10 ml/s but did not take any BPH-specific medication during TRT. The changes in prostate specific antigen (PSA), International Prostate Symptom Score (IPSS), and uroflowmetery were measured before and after TRT.
Results: After TRT, PSA remained unchanged after a year of treatment (p=0.078). Compared with their counterparts (n=229), the patients without BPH medication had similar baseline prostate characteristics in all variables, including prostate volume, IPSS, maximal flow rate, voiding volume, and PSA, except the median amount of residual urine, which was higher in the patients without BPH medication (21 ml vs. 10 ml). In the no-BPH medication group, the total IPSS score was decreased significantly (p=0.028), both in storage symptoms (questionnaire 2, 4, 7) and voiding symptoms (questionnaire 1, 3, 5, 6), while the maximal flow rate and residual urine amount remained unchanged after a year of TRT. During the median follow up of 15.1 months, no patients experienced urinary retention, BPH-related surgery, or admission for urinary tract infection.
Conclusions: Over a year of TRT for the no-BPH medication patients with moderate LUTS and maintained a relatively high maximal flow rate and improved both storage and voiding symptoms, without the clinical progression of BPH or rising PSA. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763653 | oai_dc | The Current Role of the Artificial Urinary Sphincter in Male and Female Urinary Incontinence | The Current Role of the Artificial Urinary Sphincter in Male and Female Urinary Incontinence | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"MAR Islah(Urology Unit, Department of Surgery, Kulliyyah of Medicine, Jalan Hospital, International Islamic Un); 조성용(서울특별시보라매병원); 손환철(서울대학교)"
] | The evolution of the artificial urinary sphincter has affected the current surgical options for urinary incontinence. With its unique features, the artificial urinary sphincter (AUS) has been an attractive option for the treatment of urinary incontinence regardless of gender. The current paper discusses the indications, contraindications, types of devices, surgical approaches, outcomes, and complications of the AUS in the treatment of both male and female urinary incontinence. A PubMed review of the available literature was performed and articles reporting implantation of artificial urinary sphincters for urinary incontinence in both male and female patients were evaluated. There was a comparable satisfactory continence rate after the implantation of an AUS (59∼97% in males vs. 60∼92% in females). In comparison, there were some differences in the indications, contraindications, surgical approaches, outcomes, and complications of the AUS implanted for urinary incontinence in male and female patients. AUS implantation is a safe and effective surgical option for the treatment of urinary incontinence of various etiologies. Continuous evolution of the device has made it an attractive option for the treatment of both male and female urinary incontinence. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763680 | oai_dc | Self-Reported Prevalence of and Attitudes toward Premature Ejaculation in a Community-Based Study of Married Couples | Self-Reported Prevalence of and Attitudes toward Premature Ejaculation in a Community-Based Study of Married Couples | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"황인상(전남대학교); 양동옥(전남대학교); 박광성(전남대학교)"
] | Purpose: We evaluated the self-reported prevalence of and attitudes toward premature ejaculation (PE) in a community-based study of married couples.
Materials and Methods: A community-based cross-sectional study of PE was conducted among married couples in Gwangju, Korea. Self-reported data were collected through the use of questionnaires, which included demographic questions, the Premature Ejaculation Diagnostic Tool (PEDT), the intravaginal ejaculation latency time (IELT), patient-reported outcome (PRO), and the Female Sexual Function Index (FSFI).
Results: Of the 290 couples who completed the survey, the prevalence of PEDT-diagnosed PE including probable PE was 23.7% of men. By IELT measure, the prevalence of PE was 21.7% as reported by the men and 23.9% as reported by their partners, respectively. PRO responses indicated that control over ejaculation and severity of PE were not reported significantly differently by the men and their partners. Satisfaction with sexual intercourse was poorer for the men’s partners than for the men. Personal distress and interpersonal difficulty were higher for the men than for their partners. The partners of men in the PE group had significantly lower FSFI scores than did the partners of men in the non-PE group.
Conclusions: The reporting of the prevalence of PE did not differ significantly between the men in this study and their partners. However, PE in men tended to impact their partners’ sexual function. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763658 | oai_dc | Treatment Strategy for Non-Responders to PDE5 Inhibitors | Treatment Strategy for Non-Responders to PDE5 Inhibitors | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박남철(부산대학교); 김태남(부산대학교); 박현준(부산대학교)"
] | Currently, phosphodiesterase type 5 (PDE5) inhibitors are the initial treatment option for erectile dysfunction. The reported efficacy of PDE5 inhibitors is about 70%, although it is significantly lower in difficult-to-treat subpopulations. Treatment failures might be due to the severity of the underlying pathophysiology, improper use of medication, unrealistic patient expectations, difficult relationship dynamics, severe performance anxiety, and other psychological problems. Physicians must address these issues to identify true treatment failures attributable to the drugs. This article discusses factors that might affect the response to PDE5 inhibitors and develops a strategy to maximize the overall efficacy of PDE5 inhibitors in initial non-responders to PDE5 inhibitors. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763670 | oai_dc | The Relationship between Clinical Symptoms and Urine Culture in Adult Patients with Acute Epididymitis | The Relationship between Clinical Symptoms and Urine Culture in Adult Patients with Acute Epididymitis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김성대(제주대학교); 김선욱(가톨릭대학교); 윤병일(가톨릭대학교); 하유신(가톨릭대학교); 김세웅(가톨릭대학교); 조용현(가톨릭대학교); 손동완(가톨릭대학교)"
] | Purpose: We evaluated adult patients with acute epididymitis to identify the frequency of actual sexual contacts and the causative organism, and compared clinical examinations, degrees of manifested symptoms, and radiological test results.
Materials and Methods: We reviewed the medical records of 65 patients older than 18 years presenting with acute epididymitis who had been treated between 2002 and 2011. Scrotal ultrasonography, urinalysis, and urine culture were performed to diagnose the acute epididymitis. Patients were divided into negative (n=45) and positive (n=20) urine culture groups. Then the latter groups were subdivided into a sexually transmitted organism (STO) culture group (n=13) and a non-STO (n=7) culture group. Data on any history of sexual contact, scrotal pain and tenderness, symptoms of urethritis (discharge, dysuria, urethral burning, or irritation), and lower urinary tract symptoms (dysuria, frequency, and urgency of urination) were obtained from all of the subjects.
Results: Patients in the positive urine culture group were significantly younger than those in the other group (p=0.224) and were more likely to have a history of sexual contact at least two weeks prior to onset of epididymitis (p=0.012). They had also a significantly enlarged epididymal head and significantly more severe complaints of pain or tenderness than those of latter group (p=0.348, p=0.288). However, the difference in these measures between the STO and non-STO group was not significant, except in the case of age (p=0.044).
Conclusions: Patients of the positive urine culture group with acute epididymitis were significantly younger and more sexually active than the others. They also had severe pain or tenderness and an enlarged epididymal head. There was a close association between clinical symptoms, a positive urine culture, and ultrasonographic findings. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763672 | oai_dc | Preoperative Predictors of Varicocelectomy Success in the Treatment of Testicular Pain | Preoperative Predictors of Varicocelectomy Success in the Treatment of Testicular Pain | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박연원(국립경찰병원); 이준호(국립경찰병원)"
] | Purpose: We performed the present study to evaluate the prognostic factors for the surgical outcome of varicocelectomy in the treatment of a painful varicocele.
Materials and Methods: A total of 77 patients undergoing varicocelectomy were enrolled. All the patients were examined for body mass index (BMI), varicocele grade, testosterone, follicle stimulating hormone (FSH), luteinizing hormone (LH), semen analysis, maximal vein diameter, and discrepancy of testicular volume. At a follow-up visit 3∼6 months after the surgery, the patient response was graded as a complete response, partial response, or no response. The resolution of pain was defined as a complete or partial response. We used logistic regression analyses to determine the preoperative factors for predicting a complete response and the resolution of pain.
Results: Ten subjects were lost to follow-up. The remaining 67 patients were included in this study. The pain was completely resolved in 47.8% of patients, partial resolution was observed in 25.4% of patients, and failure was reported in 26.9% of patients. Among the parameters, only a longer duration of pain (≥3 months) was an independent factor related to the complete response of pain (odds ratio, 7.371; p=0.010) and the resolution of pain (odds ratio, 7.209; p=0.042). The parameters of semen analysis results, testosterone, LH, FSH, BMI, grade, ultrasonography results, and the type of surgical approach did not significantly predict the resolution of pain.
Conclusions: The duration of pain (≥3 months) was an independent prognostic factor for the complete response of pain and the resolution of pain. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001763649 | oai_dc | Current Issues in Varicocele Management: a Review | Current Issues in Varicocele Management: a Review | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"최우석(서울대학교병원); 김수웅(서울대학교)"
] | The most common cause of male infertility is varicocele, and varicocele is the most common correctable cause of male factor infertility. In this article we reviewed the concept of varicocele in terms of its diagnosis, method of treatment, indications for treatment, treatment outcomes, and prognostic factors. Physical examination is an essential diagnostic tool in the evaluation of a patient with a varicocele. However, as it depends on subjective findings, standardization of the physical examination method is needed. Various methods for treatment of varicocele exist, including open surgical, laparoscopic, microscopic surgical, and radiologic treatment such as embolization. Among these treatment approaches, microscopic inguinal or subinguinal varicocelectomy has superior outcomes, with a low complication rate. The influence of the treatment of varicocele on fertility is still a controversial issue and a difficult question to address, because there are limitations to performing a randomized control study, and previous studies had a heterogeneity of subjects and high dropout rate. However, there is robust evidence that varicocelectomy improves semen parameters as a surrogate marker of the potential for fertility. To date, general indications for treatment of varicocele are limited in patients with proven infertility, clinical palpable varicocele, and abnormal semen characteristics. Recently, it was shown that some symptoms other than infertility could be an indication for varicocelectomy because these symptoms are frequently related to deterioration of semen parameters. Varicocele in the adolescent presents a more difficult decision regarding whether to treat. A testicular size discrepancy of more than 20% is helpful for treatment decisions. Various prognostic factors were noted in several studies without, however, a consistent consensus. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001655588 | oai_dc | A Case of Cystic Ectasia of the Rete Testis | A Case of Cystic Ectasia of the Rete Testis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"송윤섭(순천향대학교); Tae Sung Jung(Soonchunhyang University); 두승환(순천향대학교); 양원재(순천향대학교); 이동화(순천향대학교); 홍성숙(순천향대학교)"
] | The seminiferous tubules merge and connect with the tubuli recti that form the spaces known as the rete testis. Cystic ectasia of the rete testis is a rare benign testicular lesion. We report the cystic ectasia of the rete testis in a 66-year-old man. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655562 | oai_dc | Is It Possible to Recover Erectile Function Spontaneously after Cavernous Nerve Injury? Time-Dependent Structural and Functional Changes in Corpus Cavernosum Following Cavernous Nerve Injury in Rats | Is It Possible to Recover Erectile Function Spontaneously after Cavernous Nerve Injury? Time-Dependent Structural and Functional Changes in Corpus Cavernosum Following Cavernous Nerve Injury in Rats | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김태범(가천대학교); 김수웅(서울대학교); 조민철(Seoul National University Hospital); 백재승(Seoul)"
] | Purpose: There has been a scarcity of integrated, long-term (＞4 week) studies on structural and functional alterations in the penis according to the period following cavernous nerve (CN) injury. The aim of this study was to investigate time-dependent structural and functional changes in the corpus cavernosum following CN injury in a rat model.
Materials and Methods: Ninety male Sprague-Dawley rats (10 weeks old) were divided into 4 groups: normal control (C), sham (S), bilateral CN resection (R), and bilateral CN crush injury (I) groups. At 1, 4, and 12 weeks after the procedure, erectile function was assessed by electrostimulation. The terminal deoxynucleotidyl transferase-mediated 2’-deoxyuridine 5’-triphosphate nick end labeling (TUNEL) assay was performed for detection of apoptosis. Masson’s trichrome staining and immunohistochemistry were performed for detection of alpha smooth muscle actin (α-SMA). Western blot analysis was then performed.
Results: The R and I groups showed persistent impairment of erectile function at all three points in time. Apoptosis peaked at 1 week after resection or crush injury and then gradually subsided. The smooth muscle cell/collagen ratio and expression of α-SMA gradually decreased over time after CN resection or crush injury. Myosin phosphatase target subunit 1 phosphorylation progressively increased over time after CN resection or crush injury. On the other hand, expression of phospho-protein kinase B, phospho-endothelial nitric oxide synthase, and neuronal nitric oxide synthase transiently decreased at 1 week after resection or crush injury and then recovered to the control values.
Conclusions: Our results suggest that persistent up-regulation of the RhoA/Rho-kinase pathway and structural change such as decreased smooth muscle cell and increased cavernosal fibrosis might play an important role in persistent erectile dysfunction following CN injury. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655584 | oai_dc | 실시간 방광 내 압력 변화 측정을 위한 Prototype 압력 측정 센서의 유효성에 대한 기초 연구 | Preliminary Report about the Efficacy of Prototype Pressure Sensor for the Real-Time Intravesical Pressure Monitoring in the Rabbit | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김수진(가톨릭대학교); 김세웅(가톨릭대학교); 이동섭(가톨릭대학교); 김종찬(서강대학교); 조혁진(가톨릭대학교); 홍성후(가톨릭대학교); 이지열(가톨릭대학교); 황태곤(가톨릭대학교); 이호영(서강대학교); 최범규(서강대학교)"
] | Purpose: To maintain physiologic intravesical pressure is important in preventing secondary renal functional impairment in patients with voiding problems like neurogenic bladder or severe bladder outlet obstruction. Therefore, if real-time monitoring of the intravesical pressure were possible, physicians could not only monitor voiding status more precisely but also manage patients with voiding problems appropriately to protect renal function. In this study, we evaluate the validity of the prototype intravesical pressure sensor in a rabbit model.
Materials and Methods: The manufactured prototype intravesical pressure sensor was placed into the intravesical space of each of 3 rabbits. Conventional cystometry was performed and the intravesical pressure was measured by the prototype intravesical pressure sensor at the same time in all of the animals. The measured intravesical pressure by the prototype intravesical pressure sensor was compared with the measured value by conventional cystometry. The reliability between the two methods was determined using cross-table analysis.
Results: In each of the 3 animals, the index of coincidence was observed as 0.70, 0.79, and 0.77, respectively. This result meant that the intravesical pressure monitoring by the prototype intravesical pressure sensor showed good reproducibility with respect to the continuous intravesical pressure monitoring by conventional cystometry.
Conclusions: In this study, we demonstrated the reliability of the prototype intravesical pressure sensor to monitor intravesical pressure change compared with the conventional cystometric result. Further investigations to overcome the limitations of the prototype intravesical pressure sensor will be necessary for real clinical application. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655574 | oai_dc | Progression of Peyronie’s Disease during Tamoxifen Treatment | Progression of Peyronie’s Disease during Tamoxifen Treatment | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Jinwook Kim(고려대학교); Du Geon Moon(Korea University); Tae Il Rho(고려대학교); Tae Yong Park(Korea University); Soon Tae Ahn(고려대학교); Mi Mi Oh(Korea University)"
] | Purpose: Medical treatment of Peyronie’s disease with tamoxifen has been initially proposed as acting upon the early phase of the disease. As recent reports show no significant benefit of tamoxifen, we review the long term results of tamoxifen treatment of Peyronie’s disease.
Materials and Methods: Time to progression during tamoxifen treatment of patients showing acute disease and chronic disease was compared. The acute phase was identified by pain during erection. Progression was defined as enlargement of plaque size or appearance of calcification.
Results: The average treatment duration was 15.9±13.8 months (range: 3 to 48 months). The median time to progression was 7 months for acute patients and 20 months for chronic patients. Eighty percent of patients in the acute phase showed relief of pain; however, overall progression was 72.1% (78.0% for acute, 66.7% for chronic). Patient history, comorbidities, serum testosterone or initial plaque characteristics, and severity of curvature were not predictive of disease progression.
Conclusions: Tamoxifen showed no significant benefit in slowing the progression of Peyronie’s disease in the acute phase over the chronic phase. Peyronie’s disease continued to progress, though at a dampened rate for patient’s in the chronic phase. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655559 | oai_dc | Transforming Growth Factor-β Type I Receptor Inhibitor Induces Functional and Morphologic Recovery in a Rat Model of Erectile Dysfunction and Cavernous Fibrosis | Transforming Growth Factor-β Type I Receptor Inhibitor Induces Functional and Morphologic Recovery in a Rat Model of Erectile Dysfunction and Cavernous Fibrosis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"류지간(인하대학교); Jun Kyu Suh(Inha University School of Medicine); Seung Min Oh(Inha University School of Medicine); Hai Rong Jin(Incheon); 송강문(인하대학교); Mi Hye Kwon(Inha University School of Medicine); Do Kyung Kim(Incheon)"
] | Purpose: To examine the effectiveness of small-molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor, an activin receptor-like kinase 5 (ALK5), on erectile dysfunction (ED) in a rat model of cavernous fibrosis, in which fibrosis was induced by intracavernous injection of adenovirus expressing TGF-β1 (Ad-TGF-β1).
Materials and Methods: Four-month-old Sprague-Dawley rats were divided into four groups (n=10 per group): age-matched controls without treatment, age-matched controls receiving intracavernous injection of LacZ adenovirus, and cavernous fibrosis rats receiving an intracavernous injection of saline or ALK5 inhibitor (5 mg/kg). ALK5 inhibitor or saline was administered on day 5 after injection of Ad-TGF-β1. On day 30, erectile function was assessed by electrical stimulation of the cavernous nerve and the penis was then harvested for histologic studies (n=6 per group) and for the measurement of the hydroxyproline level (n=4 per group).
Results: Ad-TGF-β1-induced cavernous fibrosis rats treated with saline showed a significant decrease in cavernous smooth muscle and endothelial content, and an increase in collagen deposition, which resulted in profound deterioration of all erectile function parameters, such as the ratios of maximal intracavernous pressure (ICP), total ICP, and slope to mean arterial pressure. ALK5 inhibitor significantly restored erectile function in a rat model of cavernous fibrosis by increasing cavernous smooth muscle and endothelial content, and by blocking cavernous fibrosis.
Conclusions: The results suggest that inhibition of the TGF-β pathway is a promising therapeutic strategy for the treatment of ED related to cavernous fibrosis from various causes. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655582 | oai_dc | 전립선비대증 환자에서 베아자트Ⓡ엑스엘정 (alfuzosin 10 mg)의 안전성과 유효성에 대한 1차의료기관의 전향적 다기관 평가 | Safety and Efficacy of BearxatⓇXL Tablet (alfuzosin 10 mg) in Patients with Benign Prostatic Hyperplasia: A Prospective Multicenter Study of Primary Care Clinics | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이승주(가톨릭대학교); 조용현(가톨릭대학교); 이동섭(가톨릭대학교); 최현섭(가톨릭대학교); 신명식(명비뇨기과의원)"
] | Purpose: A prospective multi-center study was conducted to evaluate the safety and efficacy of alfuzosin (10 mg), for male lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) in primary care clinics.
Materials and Methods: Three hundred twenty-four patients with complaints of LUTS associated with BPH were enrolled from 17 clinics. Patients received a 12-week course of 10 mg alfuzosin (Bearxat®XL Tablet) once daily, and underwent follow-up at 2∼4 and 12 weeks post-treatment. The maximum flow rate (Qmax) and residual urine volume (RUV) were measured at each visit. The International Prostate Symptom Score (IPSS), Quality of Life (QoL), and International Index of Erectile Function (IIEF-5) were evaluated at baseline and post-treatment. During the study period, the presence of orthostatic hypotension was evaluated by blood pressure measurement before and after a postural change. Any adverse effects of alfuzosin including retrograde ejaculation were assessed.
Results: Of the 324 enrolled patients, 62 (19.1%) patients dropped out and a total of 262 patients were evaluated. Each value of Qmax, RUV, IPSS, QoL, and IIEF-5 was significantly improved from 14.19±8.85 ml/sec, 41.10±81.44 ml, 18.04±7.36, 3.81±0.86, and 11.75±6.91, respectively, at baseline, to 15.68±6.25 ml/sec, 24.29±29.46 ml, 12.19±5.59, 2.54±0.91, and 12.33±7.55, respectively, at end-point. Retrograde ejaculation was found in 2 patients (2/255, 0.78%) at 2∼4 weeks and 1 patient (1/152, 0.66%) at 12 weeks. The frequency of orthostatic hypotension was 13.27% (30/226) at baseline, 13.11% (27/206, p=0.8658) at 2∼4 weeks, and 14.29% (19/133, p=0.8348) at end-point. The number of patients with adverse events was 36 where the number of adverse events was 60. Among those 60 adverse events, 8 events were related to treatment, which consisted of headache (2), dizziness (2), palpitation (1), voiding difficulty (1), erectile dysfunction (1), and arthralgia (1).
Conclusions: Treatment with alfuzosin (10 mg) once daily led to significant improvements in LUTS associated with BPH and QoL in primary care clinic patients. alfuzosin (10 mg) use resulted in few hypotensive events, no deleterious effect on sexual function, and no drug related SAEs during the study. The study findings suggest that alfuzosin (10 mg) can be safely prescribed in primary care clinics for male LUTS with efficacy. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655554 | oai_dc | 5알파환원효소 | 5α-Reductase | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박정세(박비뇨기과의원); 백재승(서울대학교); 조민철(동국대학교)"
] | Androgen acts via the androgen receptor and can play a critical role in the development and growth of the prostate and the pathophysiology of prostatic diseases. Testosterone is the most abundant circulating androgen and is converted to dihydrotestosterone (DHT), a more potent androgen, by steroid 5α-reductase. There are two 5α-reductase isoenzymes, type 1 and type 2, in humans and animals. Type 2 5α-reductase predominates in the prostate. While deficiency of type 2 5α-reductase causes male pseudohermaphroditism, increased DHT has been implicated in benign prostatic hyperplasia and prostate cancer. The aim of this article is to highlight the significance of 5α-reductase in the development and growth of the prostate and pathogenesis of prostatic diseases. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655555 | oai_dc | 여성 성기능장애의 호르몬 보충치료 | Hormone Replacement Therapy in Female Sexual Dysfunction | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"윤하나(이화여자대학교)"
] | Female sexual function is highly complex and deeply influenced by hormonal and non-hormonal factors. As sexual dysfunction becomes a common and important problem for women of all ages with related quality of life issues, we need to understand more about the effect of sex steroid hormones in female sexual function. However, there are limited data about the correlation between the value of sex steroid hormones- testosterone, in particular-and female sexual function. In a certain type of female sexual dysfunction (FSD), hypoactive sexual desire disorder, for example, there is evidence that treatment with androgens or with estrogens is effective. To widen the therapeutic options of hormone replacement therapy in FSD, further research is needed as to the benefits and risks of hormonal treatments in both pre- and post-menopausal women. Although important unanswered questions still exist in hormonal treatment of FSD, new therapeutic strategies are being studied and many ongoing clinical trials are expecting favorable results leading to more successful treatment of FSD. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655567 | oai_dc | Impact of Nocturia on Abnormal Daytime Sleepiness in Men with Lower Urinary Tract Symptoms/Benign Prostate Hyperplasia | Impact of Nocturia on Abnormal Daytime Sleepiness in Men with Lower Urinary Tract Symptoms/Benign Prostate Hyperplasia | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"두승환(순천향대학교); 송윤섭(순천향대학교); Hong Jun Lee(Chung-Ang University); 양원재(순천향대학교); Hong Cheol Ahn(Soonchunhyang University); Jung Hoon Kim(Chung-Ang University); Si Jung Park(Chung-Ang University); Jin Ahn(Chung-Ang University)"
] | Purpose: Nocturia is one of the most bothersome lower urinary tract symptoms (LUTS). The aim of the present study is to determine whether severe-nocturia have impact on the abnormal daytime sleepiness in men with LUTS/benign prostate hyperplasia (BPH).
Materials and Methods: Severe-nocturia was classified as twice or more per night. A total of 85 men met the criteria and constituted the study cohort. The patients had a detailed clinical evaluation, including a complete history, physical examination, urine analysis, urine culture, a digital rectal examination, serum prostate-specific antigen (PSA) level, prostate volume by transrectal ultrasonography, uroflowmetry and postvoid residual urine volume. LUTS and symptom-specific quality of life (QoL) were assessed using the IPSS. Patients were asked to complete an Epworth Sleepiness Scale questionnaire for daytime sleepiness.
Results: 43 patients had less than one, 42 patients had more than two episodes of nocturia. There was no significant difference of age, total prostate volume, PSA levels between patients with mild-nocturia and severe-nocturia. There was no significant difference of maximum flow rate (Qmax), voided volume and postvoid residual urine volume (PVR) between patients with mild-nocturia and severe-nocturia. There was significant decrease of total International Prostate Symptom Score (IPSS) scores and QoL index in patients with severe-nocturia compared in patients with mild-nocturia. The number of patients with abnormal daytime sleepiness in mild-nocturia and severe-nocturia were 4.7% (2/43), 16.7% (7/42), respectively (p＜0.05). Regression coefficiency between percent of nocturia and total score of daytime sleepiness was significant (p＜0.05) and regression coefficient (R) was 0.29.
Conclusions: Our results indicate that severe-nocturia had impact on the abnormal daytime sleepiness in patients with LUTS. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655586 | oai_dc | Testicular Seminoma Incidentally Detected by Spermatic Cord Torsion | Testicular Seminoma Incidentally Detected by Spermatic Cord Torsion | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"오미미(고려대학교); 문두건(고려대학교); Ji Sung Shim(Korea University); Sun Tae Ahn(Korea University); Tae Yong Park(Korea University); Su Hwan Shin(Korea University); Suk Cho(Korea University); Sang Woo Kim(Korea University); Jong Jin Park(Korea University)"
] | We recently encountered a very rare case of torsion of an intrascrotal testicular tumor in a 26-year-old male. Unlike the intra-abdominal undescended testis, intrascrotal spermatic cord torsion associated with a testicular tumor has rarely been reported. We write to report a case of intrascrotal spermatic cord torsion accompanied by a testicular tumor that had been overlooked preoperatively. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655580 | oai_dc | 만성 세균성 전립선염 흰쥐 모델에서 셀레늄 함유 온천수 음용의 항염 및 항균효과 | The Anti-inflammatory and Antimicrobial Effects of Selenium-rich Hot Spring Water on a Chronic Bacterial Prostatitis Rat Model | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"윤병일(가톨릭대학교); 김세웅(가톨릭대학교); 배웅진(가톨릭대학교); 하유신(가톨릭대학교); 홍성후(가톨릭대학교); 이지열(가톨릭대학교); 윤건호(가톨릭대학교); 황태곤(가톨릭대학교); 조용현(가톨릭대학교)"
] | Purpose: The conventional primary therapy for chronic bacterial prostatitis (CBP) is the use of antibiotics. However, the therapy has a low cure rate and long-term use of antibiotics can lead to adverse effects including bacterial resistance. For these reasons, a new therapy for CBP is strongly needed.
Materials and Methods: To evaluate the anti-inflammatory and antimicrobial effects of selenium-rich hot spring water on CBP, rats were divided into four groups and treatment was administered for four weeks as follows: (1) control (n=8), (2) ciprofloxacin (n=8), (3) selenium-rich hot spring water (n=8), and (4) selenium-rich hot spring water with ciprofloxacin (n=8). Drip infusion of bacterial suspension (E. coli Z17 O2:K1;H−) into Spargue-Dowley rats was then conducted to induce CBP. Four weeks later, the results of prostate tissue and urine culture and histological analysis on the prostate were analyzed in each group.
Results: The use of ciprofloxacin, and selenium-rich hot spring water with ciprofloxacin showed statistically significant decreases in bacterial growth and improvements in prostatic inflammation compared with the control group (p＜0.05). The selenium-rich hot spring water with ciprofloxacin group showed a statistically significantly lower rate of bacterial growth and and greater improvements in prostatic inflammation than the ciprofloxacin group (p＜0.05).
Conclusions: These results suggest that spring water may be an effective material in the treatment of CBP. Notably, the combination treatment of selenium-rich hot spring water and ciprofloxacin has synergistic effects. Therefore, we can suggest that the combination of selenium-rich hot spring water and ciprofloxacin may be effective in the treatment of CBP, and with a higher success rate than ciprofloxacin alone. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655577 | oai_dc | 폐경 전 여성의 성기능장애의 유병률과 관련 요인: 지역사회 연구 | The Prevalence and Associated Factors of Female Sexual Dysfunction in Korean Premenopausal Women: A Community-Based Study | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"양동옥(전남대학교); 박광성(전남대학교); 황인상(전남대학교)"
] | Purpose: To estimate the prevalence of and factors associated with female sexual dysfunction (FSD) in Korean women.
Materials and Methods: A total of 629 married women in the Chonnam and Gwangju area were randomly included in this study. They were asked to complete a questionnaire on FSD, which consisted of the Female Sexual Function Index (FSFI), as well as psychological, physiological, and demographic factors.
Results: The mean age of the women was 36.97 years and the mean FSFI score was 25.56 out of a total score of 36. Based on the total FSFI score, 42.9% of the women had scores less than the cut-off point of 25, the assessed definition of FSD. The prevalence of FSD by age group was: 31.3% for 20∼29 year olds, 41.6% for 30∼39 year olds, and 51.8% for 40∼49 year olds. A stepwise regression analysis found that women with higher levels of sexual distress, lower frequency of sexual intercourse, lower levels of life satisfaction, a less important appraisal of sex, a higher likelihood of depression, more conservative attitude toward sex, irregular menstrual cycle, higher age, chronic disease, and a smoking habit were more likely to suffer from FSD.
Conclusions: The prevalence of FSD in Korean women was common and comparable to those reported worldwide. Sexual distress, frequency of sexual intercourse, and life satisfaction were important associated factors of FSD. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001655570 | oai_dc | Comparison of Clinical Efficacy of Finasteride and Dutasteride as 5-alpha Reductase Inhibitor | Comparison of Clinical Efficacy of Finasteride and Dutasteride as 5-alpha Reductase Inhibitor | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Hoon Choi(Department of Urology, College of Medicine, Konyang Universtiy, Daejeon, Korea); Young Seop Chang(Department of Urology, College of Medicine, Konyang Universtiy, Daejeon, Korea); Byung Hun Park(Department of Urology, College of Medicine, Konyang Universtiy, Daejeon, Korea); Dong Hoon Ko(Department of Uro... | Purpose: To compare the clinical therapeutic efficacy of finasteride and dutasteride as 5-alpha reductase inhibitor (5-ARI) in the medical treatment of benign prostate hyperplasia.
Materials and Methods: From July 2007 to July 2010, 354 benign prostatic hyperplasia patients with combination medication：alpha blocker plus 5-ARI were enrolled. These patients were classified into a finasteride medication group (F group) and dutasteride medication group (D group) retrospectively. We initially measured the total prostate volume (TPV), prostate specific antigen (PSA), International Prostate Symptom Score (IPSS), quality of life score (QoL), maximal flow rate (Qmax), and post-void residual urine (PVR). After at least twelve months of medication, we rechecked these clinical parameters and during medication, side effects related to medication were also recorded.
Results: The F group (n=129) and D group (n=225) showed no differences in baseline characteristics for age, TPV, IPSS, QoL scores, or PSA. After medication, decreases in TPV were relatively higher in the D group than the F group (28.2% vs 20.5%). In addition, the decrease in PSA (43.6% vs 39.2%) and IPSS score (4.6 vs 3.5) were also higher in the D group. There were no significant differences in QoL score, Qmax, PVR change, or side effects between the two groups.
Conclusions: Dutasteride showed greater efficacy in reduction of TPV and PSA and in symptomatic improvement by IPSS score than finasteride. More large scale studies about the differences on clinical efficacy of finasteride and dutasteride are needed. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001720404 | oai_dc | Can 80 W KTP Laser Vaporization Effectively Relieve the Obstruction in Benign Prostatic Hyperplasia?: A Nonrandomized Trial | Can 80 W KTP Laser Vaporization Effectively Relieve the Obstruction in Benign Prostatic Hyperplasia?: A Nonrandomized Trial | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Deok Hyun Han(Sungkyunkwan University); Seol Ho Choo(Sungkyunkwan University); Jin Woo Chung(Sungkyunkwan University); 홍정희(단국대학교); Sung Won Lee(Sungkyunkwan University)"
] | Purpose: There is little data evaluating the changes of severity of bladder outlet obstruction after 80 W-potassium-titanyl- phosphate (KTP) photoselective laser vaporization prostatectomy (PVP) by pressure-flow study. We evaluated the efficacy of PVP to relieve the obstruction in benign prostate hyperplasia (BPH) compared with transurethral resection of the prostate (TURP).
Materials and Methods: This is a prospective, non-randomized single center study. The inclusion criteria were as follows: Men suffering from lower urinary tract symptoms (LUTS) secondary to BPH, age ≥50 years, International Prostatic Symptom Score (IPSS) ≥13, maximum flow rate (Qmax) ≤15 ml/s, and ability to give fully informed consent. Patients with neurogenic cause or detrusor underactivity were excluded. The IPSS, bother score, Qmax, postvoid residual volume (PVR), detrusor pressure at maximum flow rate (PdetQmax), bladder outlet obstruction index (BOOI), and prostate volume were measured before and 6 months after surgery and compared between PVP and TURP.
Results: Sixty-seven patients (53 in PVP, 14 in TURP) were evaluable. In both groups, the IPSS, bother score, Qmax, and PVR had significantly improved (p＜0.05), and there were no differences between the changes in those parameters. PVP could effectively reduce the PdetQmax, prostate volume, and BOOI from baseline (from 68.7±23.3 to 40.6±11.2 cmH2O, 49.5±16.3 to 31.3±12.1 ml, 49.8±25.6 to 9.8±20.7), similar to TURP. There were no differences in postoperative PdetQmax, prostate volume, or BOOI between the two groups. The percentage of patients with BOOI ≥40 was decreased from 64% to 4% in the PVP group and from 86% to 14% in the TURP group.
Conclusions: PVP could reduce the prostate volume effectively and relieve bladder outlet obstruction similar to TURP by the 6-month follow up in men with BPH. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001720423 | oai_dc | Metastatic Squamous Cell Carcinoma of the Kidney from Cholangiocarcinoma | Metastatic Squamous Cell Carcinoma of the Kidney from Cholangiocarcinoma | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Hoon Choi(Korea University); Tae Il Noh(Korea University); Byeong Kuk Ham(Korea University); 박재영(고려대학교); Kang Soo Shim(Andong Hospital); Jae Hyun Bae(Korea University)"
] | We present a rare case of a metastatic renal tumor originating from adenosquamous carcinoma of the intrahepatic bile duct. A 64-year-old man treated with bisegmentectomy and extended cholecystectomy for cholangiocarcinoma had a left cystic renal mass, which had irregular wall thickening, heterogeneously low attenuation, and soft tissue infiltration as determined by a computed tomography scan. The first impression was renal abscess. Left nephrectomy was performed and the nonencapsulated mass was gray in color macroscopically. Histological examination of the specimen revealed alveolar proliferation of small cancer cells, which was consistent with the original tumor of the intrahepatic bile duct. The left renal tumor was misdiagnosed as a renal abscess but finally diagnosed as squamous cell carcinoma metastasized from the intrahepatic bile duct. The patient expired because of lung metastasis after 14 months following left nephrectomy. In our opinion, this case would be the first report of a renal metastasis from a cholangiocarcinoma clinically and was treated with nephrectomy. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001720413 | oai_dc | Preoperative Factors Influencing Postoperative Results after Vasovasostomy | Preoperative Factors Influencing Postoperative Results after Vasovasostomy | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"신유섭(Chonbuk National University); Sang Deuk Kim(Chonbuk National University); 박종관(전북대학교)"
] | Purpose: The purpose of this study is to evaluate the preoperative factors that influenced postoperative sperm concentration after vasovasostomy.
Materials and Methods: We retrospectively reviewed 97 consecutive single-layer vasovasostomy procedures performed by a single surgeon between March 2003 and September 2010. The patients were stratified into three groups based on sperm concentration at 1 month follow-up: group I-azoospermia, group II-oligospermia, and group III-normal. We evaluated the preoperative factors that may have influenced sperm concentration at postoperative 1 month. Patients with serial semen analysis were divided into four groups according to the change in postoperative sperm concentration at the 6-month visit: group II-N-from oligospermia to normal, group II-O-from oligospermia to oligospermia, group III-O-from normal to oligospermia, group III-N-from normal to normal. We compared the pregnancy rate among the four groups.
Results: The mean obstructive interval was 9.69 years in group I, 6.02 years in group II, and 7.82 years in group III. There were significant differences found among the groups (p=0.035). There was significantly different change in sperm concentration, sperm motility, and sperm morphology between each of the groups. A total of 32 patients underwent serial semen analyses at 1 month, 3 months, and 6 months after vasovasostomy. There was no significant difference in patient age, obstructive interval, or follicle-stimulating hormone among the groups. The natural pregnancy rate in group II-O was lower than that in group II-N, and in group III-O was lower than that in group III-N. However, there was no significant difference among each of the groups.
Conclusions: The sperm concentration after vasovasostomy was significantly related to the obstructive interval between vasectomy and reversal. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001720417 | oai_dc | Inverted Papilloma of the Prostatic Urethra Arising in a Juvenile | Inverted Papilloma of the Prostatic Urethra Arising in a Juvenile | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"신유섭(Chonbuk National University); 박종관(전북대학교)"
] | Inverted papilloma of the urinary tract is a rare benign lesion. We report, to our knowledge, the first case of inverted papilloma of the prostatic urethra arising in a juvenile. Our patient was referred for evaluation of painless, gross hematuria and voiding difficulty. Transrectal sonography demonstrated a 1.4 cm papillary lesion on the medial aspect of the prostatic urethra. Cystoscopy showed a solitary, papillary tumor on the prostatic urethra. Transurethral resection was performed and histological examination showed an inverted papilloma. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001720414 | oai_dc | Relationship between Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia and Metabolic Syndrome in Korean Men | Relationship between Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia and Metabolic Syndrome in Korean Men | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Yeon Won Park(National Police Hospital); Seung Ki Min(National Police Hospital); Jun Ho Lee(National Police Hospital)"
] | Purpose: To investigate any associations between lower urinary tract symptoms (LUTS)/benign prostate hyperplasia (BPH) and metabolic syndrome (MetS).
Materials and Methods: In all, 1,224 male police officers in their 50s who had participated in health examinations were included. LUTS/BPH was assessed by serum prostate-specific antigen, International Prostate Symptom Score (IPSS), transrectal ultrasonography, maximum urinary flow rate (Q max), and postvoid residual urine volume (PVR). In addition, testosterone was also examined. The MetS was defined using NCEP-ATP III guidelines. We used the multiple linear regression test and logistic regression analyses to examine the relationships.
Results: MetS was diagnosed in 29.0% of participants. There was no significant difference in the percentage of cases of BPH (IPSS ＞7, Q max ＜15 ml/sec, and prostate gland volume ≥ 20 ml) (14.2% in the non-MetS group vs. 17.2 in the MetS group; p value= 0.178). The total IPSS score and the Q max were not significantly different. The prostate volume and PVR were significantly greater in the subjects with MetS. After adjusting for age and testosterone, the presence of MetS was not associated with BPH (multivariate odds ratio, 1.122; 95% confidence interval, 0.593∼2.120). Additionally, MetS was not related to IPSS (Beta, −0.189; p value=0.819), prostate volume (Beta, 0.815; p value=0.285), Q max (Beta, −0.827; p value=0.393), or PVR (Beta, 0.506; p value=0.837).
Conclusions: According to our results, the MetS was not clearly correlated with LUTS/BPH in Korean men in their 50s. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001720402 | oai_dc | Antipsychotic-Induced Sexual Dysfunction and Its Management | Antipsychotic-Induced Sexual Dysfunction and Its Management | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Yeon Won Park(National Police Hospital); Yooseok Kim(National Police Hospital); Jun Ho Lee(National Police Hospital)"
] | Sexual dysfunction is a common condition in patients taking antipsychotics, and is the most bothersome symptom and adverse drug effect, resulting in a negative effect on treatment compliance. It is known that hyperprolactinemia is a major cause of sexual dysfunction. Based on the blockade of dopamine D2 receptors, haloperidol, risperidone, and amisulpride are classed as prolactin-elevating antipsychotics, while olanzapine, clozapine, quetiapine, ziprasidone, and aripiprazole are classed as prolactin-sparing drugs. Risperidone and the other typical antipsychotics are associated with a high rate of sexual dysfunction as compared to olanzapine, clozapine, quetiapine, and aripiprazole. With regard to treatment in patients suffering from sexual dysfunction, sildenafil was associated with significantly more erections sufficient for penetration as compared to a placebo. Subsequent studies are needed in order to provide physicians with a better understanding of this problem, thereby leading toward efficacious and safe solutions. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001720408 | oai_dc | Sexual Behavior of the Elderly in Urban Areas | Sexual Behavior of the Elderly in Urban Areas | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Hyun Cheol Jeong(Hallym University); Sin Uk Kim(Hallym University); Wan Chul Lee(Hallym University); Ma Tae Kim(Hallym University); 이원기(한림대학교); 김하영(한림대학교); Sung Yong Kim(Hallym University); 양대열(한림대학교)"
] | Purpose: This study aimed at investigating sexual behavior patterns of elderly residents of urban areas in South Korea and their correlation with lower urinary tract symptoms.
Materials and Methods: From May, 2009 to October, 2009, 154 males and 299 females over 60 years old who visited senior welfare centers of Seoul were administered a questionnaire on sex life patterns and voiding symptoms.
Results: Among the 154 males, 59 (38.3%) had sexual intercourse at least one time per month. The remaining 95 males (61.7%) did not have sexual intercourse, because of impotence for 52 males (52.6%), no sexual desire for 28 males (29.4%), and sex partner’s problems for 15 males (15.7%). The higher International Prostate Symptom Score was, the lower International Index of Erectile Dysfunction-5 was (p=0.035). Among 299 females, 37 (12.4%) had sexual intercourse at least one time per month. The remaining 262 females (87.6%) did not have sexual intercourse, because of no spouse for 163 females (63.2%), no sexual desire for 48 females (18.6%), the spouse’s impotence for 34 females (13.2%), and the spouse’s bad health for 10 females (3.9%). It was found that self-diagnosis of overactive bladder affects sex life negatively.
Conclusions: The sexual behaviors of the elderly included varying activity. Sexual intercourse were significantly associated with lower urinary tract symptoms. Our results suggest that the counseling with the elderly about sexual health is as important as it is with non-elderly individuals. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001720411 | oai_dc | Survey on the Perception of Urogenital Complications in Diabetic Patients | Survey on the Perception of Urogenital Complications in Diabetic Patients | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김종욱(고려대학교); Ji Yun Chae(고려대학교); Jinwook Kim(고려대학교); CheolYongYoon(고려대학교); Mi Mi Oh(고려대학교); 김제종(고려대학교); 문두건(고려대학교)"
] | Purpose: Retinopathy, neuropathy, and nephropathy are well-known complications of diabetes; they are often expected to occur and, therefore, are usually tested for. However, urogenital complications, such as sexual and voiding dysfunctions, are less well known, and consequently, many patients are not treated appropriately despite their symptoms. Thus, we surveyed diabetic patients with regard to their perception of urogenital complications.
Materials and Methods: We designed a survey for patients in our hospital who were being treated for diabetes mellitus (DM). The questionnaire included items on age, sex, treatment duration, treatment options for and the level of perception of urogenital symptoms, the presence of urogenital symptoms, and whether treatment was intended or had been initiated.
Results: In total, 275 patients participated in the survey. The perception questions on DM-associated urogenital complications showed that 89 patients (32.4%) had no knowledge, 84 patients (30.5%) had some knowledge, and 102 patients (37.1%) had detailed knowledge about these complications. A total of 124 patients (45.1%) reported urogenital symptoms: 93 patients (75.0%) reported voiding dysfunction and 61 patients (49.2%) reported sexual dysfunction. Common symptoms of voiding dysfunction were urinary frequency, nocturia, sense of residual urine, weak stream, and urinary incontinence. Common symptoms of sexual dysfunction were reduced libido, and erectile and ejaculatory dysfunction.
Conclusions: The survey showed that the subjective prevalence rate of urogenital symptoms in diabetic patients was 45.1%. However, only a small percentage (37.1%) of the patients cognized that these symptoms were associated with DM. Therefore, it is necessary to properly inform and educate diabetic patients on possible urogenital complications that may occur. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001720418 | oai_dc | Vesico-Appendiceal Fistula Misdiagnosed as Meckel’s Diverticulum: A Laparoscopic Approach | Vesico-Appendiceal Fistula Misdiagnosed as Meckel’s Diverticulum: A Laparoscopic Approach | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Jung Woo Lee(Pusan National University); Jae Hyun Ahn(Pusan National University); Hong Koo Ha(Pusan National University)"
] | A 26-year-old man complained of a vague low abdominal discomfort for the previous 2 months. Radiologic evaluations demonstrated that there was tubular structure connected with the right side wall of the bladder, suggesting Meckel’s diverticulum with fistula formation to the bladder as well as a mass-like bladder wall thickening. With an impression of Meckel’s diverticulum with fistula with the bladder, laparoscopic surgery was performed to confirm a diagnosis and to manage the Meckel’s diverticulum with fistula with the bladder. The distal tip of the appendix was firmly attached to the right side of the bladder. The final diagnosis was corrected by laparoscopy followed by laparoscopic appendectomy and fistula repair. Vesico-appendiceal fistula is an uncommon type of vesico-enteral fistula and a rare complication of unrecognized appendicitis. Additionally, this report showed the significant value of laparoscopy as a diagnostic and therapeutic tool to this entity. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001720416 | oai_dc | Penile Abscess Secondary to Neglected Penile Fracture after Intracavernosal Vasoactive Drug Injection | Penile Abscess Secondary to Neglected Penile Fracture after Intracavernosal Vasoactive Drug Injection | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Wan Song(Sungkyunkwan University); 고광진(한림대학교부속강남성심병원); Seung Jea Shin(Sungkyunkwan University); 류동수(성균관대학교)"
] | Penile abscesses are rare, but can develop after trauma, injection therapy, or surgery of the penis, or as an unusual presentation of sexually transmitted diseases. We report a case of penile abscess in a 51-year-old diabetic man, presented 9 days after neglected penile fracture following intracavernosal injection therapy and sexual intercourse. Penile ultrasonography and surgical exploration confirmed the physical examination findings of involvement of the corpus cavernosum. The pus culture from the abscess revealed Enterococcous faecalis. The patient was successfully treated by surgical drainage of the abscess and primary closure of the ruptured tunica albuginea. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001689247 | oai_dc | Therapeutic Angiogenesis as a Potential Future Treatment Strategy for Erectile Dysfunction | Therapeutic Angiogenesis as a Potential Future Treatment Strategy for Erectile Dysfunction | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"류지간(인하대학교); 서준규(인하대학교)"
] | The cavernous endothelium plays a crucial role in regulating the tone of the underlying smooth muscle and physiologic penile erection. Recently, the link between erectile dysfunction (ED) and cardiovascular disease was unveiled, and the main etiology of ED was found to be vasculogenic. Although oral phosphodiesterase-5 inhibitors are generally effective for men with ED, such therapies do not cure underlying vasculopathy in the corpus cavernosum tissue. This review addresses current preclinical protein, gene, and cell or stem cell therapies for enhancing cavernous endothelial regeneration and restoring erectile function. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001689427 | oai_dc | Prevalence of Benign Prostatic Hyperplasia on Jeju Island: Analysis from a Cross-sectional Community-based Survey | Prevalence of Benign Prostatic Hyperplasia on Jeju Island: Analysis from a Cross-sectional Community-based Survey | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"허정식(제주대학교); 김성대(제주대학교); 김영주(제주대학교)"
] | Purpose: We report on the prevalence of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) among men of Jeju Island, representing a coastal and insular area, using a cross-sectional community-based survey.
Materials and Methods: A total of 553 participants in a prostate health screening campaign on Jeju Island were subjected to measurements of the International Prostate Symptom Score (IPSS), prostate volume, uroflowmetry, postvoiding residual urine volume, and prostate-specific antigen levels. Eliminating 58 participants who were suspected of having prostate cancer, we analyzed the data from 495 participants. The definition of BPH was a combination of moderate IPSS (8∼19) to severe IPSS (＞19) and prostate enlargement (＞30 g on transrectal ultrasonography).
Results: The prevalence of BPH was 21.0% overall: 11.6% among subjects aged 50∼59 years, 18.1% for those aged 60∼69, 30.8% for those aged 70∼79 and 50.8% among those aged 80 years or more. Compared with previous studies in urban or rural areas, the prevalence was slightly lower. The prevalence of BPH and of moderate to severe LUTS increased with age and showed significant differences between age groups (p=0.028 and 0.033, respectively). A positive correlation was found between the IPSS and quality of life score. Among subunits of IPSS, the nocturia score contributed most to the severity of LUTS and had the highest correlation with a quality of life score.
Conclusions: The overall prevalence of BPH in this study was 21.0%, which is slightly lower than in previous studies in urban or rural areas. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001689446 | oai_dc | A Case of Pediatric Paratesticular Rhabdomyosarcoma with Epididymitis | A Case of Pediatric Paratesticular Rhabdomyosarcoma with Epididymitis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김영주(제주대학교); 김성대(제주대학교); 허정식(제주대학교); 현창림(제주대학교)"
] | Paratesticular rhabdomyosarcoma is a rare malignancy arising from the mesenchymal tissues of the spermatic cord, epididymis, testis, and testicular tunica, and accounts for approximately 7% of all rhabdomyosarcomas. It often occurs in children but is known to have a better prognosis than disease at other urogenital sites. Patients typically present with painless unilateral scrotal swelling like a solid testicular tumor. However, we report an unusual case of delayed diagnosis of paratesticular rhabdomyosarcoma accompanied by epididymitis manifesting an painful scrotal swelling. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001689432 | oai_dc | A Case of Tuberculous Prostatitis with Abscess | A Case of Tuberculous Prostatitis with Abscess | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"두승환(순천향대학교); 송윤섭(순천향대학교); 김재헌(순천향대학교); 양원재(순천향대학교); 김순임(순천향대학교); 이동화(순천향대학교); 홍성숙(순천향대학교)"
] | We present a case of acute prostatitis with abscess. The patient had undergone intravesical bacillus Calmette-Guérin (BCG) immunotherapy for bladder cancer. A prostate biopsy demonstrated tuberculous prostatitis with abscess. This case illustrates that when bladder cancer is treated with BCG, a tuberculous prostate abscess can develop. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001689388 | oai_dc | Time-Dependent Changes of Erectile Function in Diabetic Rats: Role of Systemic Endothelial Dysfunction | Time-Dependent Changes of Erectile Function in Diabetic Rats: Role of Systemic Endothelial Dysfunction | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Woo Suk Choi(Seoul National University); 김수웅(서울대학교); Kwanjin Park(Seoul National University); 백재승(서울대학교)"
] | Purpose: To understand the potential contribution of systemic endothelial dysfunction to diabetic erectile dysfunction, and the time course of erectile dysfunction in a streptozotocin (STZ)-induced diabetic rat model.
Materials and Methods: Among 84, 12-week-old Sprague-Dawley rats, 48 rats received intraperitoneal STZ and were classified into six groups of diabetes by the period of observation (n=8). The remaining 36 rats were also grouped, similar to the diabetic groups, and served as normal controls. After 4, 6, 8, 10, 12, and 14 weeks of diabetes (serum glucose ＞250 mg%), all rats underwent cavernous nerve electrostimulation (3 V, 0.2 ms, 30 sec) with varying frequency (2.5∼20 Hz). At the end of the study, 8 ml of blood was taken to measure the plasma markers of endothelial function and glycosylated hemoglobin.
Results: Compared to the control, significant reduction of erectile response was not observed until eight weeks after diabetes induction. The diabetic rats had elevation of all plasma markers except for l-selectin. However, the correlation analysis revealed that no systemic marker of endothelial dysfunction was associated with change in erectile function. Only the level of hemoglobin A1c (HbA1c) showed a modest but significant correlation with the peak intracavernosal pressure, corrected by mean arterial pressure (ρ=−0.183), and the area under the curve of the cavernosometry (ρ=−0.207).
Conclusions: Significant reduction of erectile function was not observed until eight weeks after the induction of diabetes. Except for HbA1c, there was no systemic marker associated with endothelial activation and erectile function in the diabetic rats. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001689252 | oai_dc | Prostate Cancer and Sexual Function | Prostate Cancer and Sexual Function | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"현재석(경상대학교)"
] | Prostate cancer is now ranked fifth in incidence among cancers in Korean adult males. This is attributable to the more Westernized dietary style which increases the morbidity of prostate cancer and the development of cancer diagnostic technologies, such as prostate-specific antigen and advanced medical systems, increasing the rate of prostate cancer diagnosis. Prostate cancer effects include not only erectile dysfunction caused by the disease itself, but also by psychiatric disorders caused by prostate cancer or its treatments. Prostate cancer by itself reduces sexual desire and the frequency of sexual intercourse. Additionally, surgery or hormonal therapy to block testosterone further increases the frequency of erectile dysfunction. Erectile dysfunction following radical prostatectomy is primarily attributable to nerve injury caused by intraoperative nerve traction, thermal injury, ischemic injury, and local inflammatory reactions. Additionally, the absence of nocturnal penile tumescence causes persistent hypoxia of the corpus cavernosum, which, secondarily, causes anatomical and functional changes in the corpus cavernosum. Preservation of erectile function is one of the most significant issues for patients with local prostate cancer. Erectile dysfunction following radical prostatectomy is known to have various prognoses, depending on preservation of the neurovascular bundle, patient age, and preoperative erectile status. Intracavernosal injections, PDE5 inhibitors, and penile rehabilitation therapy using a vacuum constriction device after radical prostatectomy are known to improve the recovery of erectile function. Recently, testosterone replacement therapy has also drawn attention as a treatment method. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001689419 | oai_dc | Strong Impact of Nocturia on Sleep Quality in Patients with Lower Urinary Tract Symptoms | Strong Impact of Nocturia on Sleep Quality in Patients with Lower Urinary Tract Symptoms | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"두승환(순천향대학교); 송윤섭(순천향대학교); 이홍준(중앙대학교); Jin Ahn(Chung-Ang University); 김재헌(순천향대학교); 윤종현(순천향대학교); 양원재(순천향대학교)"
] | Purpose: Nocturia is a bothersome symptom that impacts sleep quality in patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH). This study was performed to evaluate the impact of nocturia on sleep quality.
Materials and Methods: A total of 58 male patients with LUTS/BPH were enrolled. LUTS/BPH patients without nocturia were included in the control group. The inclusion criteria were eight or more points on the International Prostate System Score (IPSS) including more than one episode of nocturia and a prostate volume larger than 20 ml. IPSS, prostate volume, uroflowmetry, and the Pittsburgh Sleep Quality Index (PSQI) from each patient were recorded.
Results: Patients with nocturia showed a higher mean global PSQI (8.5±0.4) than patients without nocturia (4.82±0.4) (p＜0.01). Patients with nocturia showed a higher percentage of severe sleep disorders (74.1%) than patients without nocturia (35.3%) (p＜0.01). The regression coefficient between the number of episodes of nocturia and mean global PSQI was 0.42 (p＜0.01).
Conclusions: Patients with nocturia showed poor sleep quality, and this was related to the number of episodes of nocturia. This suggests that nocturia has a strong impact on sleep quality in patients with LUTS/BPH. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000251.xml | ||
ART001689451 | oai_dc | Torsion of an Indirect Hernia Sac Causing Acute Scrotal Swelling in a Child | Torsion of an Indirect Hernia Sac Causing Acute Scrotal Swelling in a Child | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"남종길(부산대학교); Jae Hyun Ahn(Pusan National University); Hyeon Woo Kim(Pusan National University); 박현준(부산대학교); 이상돈(부산대학교); 정문기(부산대학교)"
] | Torsion of a hernia sac is an extremely rare condition that presents as acute scrotum in children. We report a case of a 6-year-old boy who presented with an acute scrotum and was found during surgical exploration to have torsion of an indirect hernia sac associated with hydrocele. Upon scrotal exploration, deterioration of the scrotum due to inflammatory changes was found. A necrotic cyst was recognized within a communicating hydrocele of the scrotum and was twisted at an angle of about 360°. All urologists should be aware of this special condition in the differential diagnosis of acute scrotum. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000252.xml | ||
ART001689441 | oai_dc | Concurrent Bladder Lymphoma and Bladder Cancer Presenting as Metastatic Bladder Cancer | Concurrent Bladder Lymphoma and Bladder Cancer Presenting as Metastatic Bladder Cancer | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김재헌(순천향대학교); 박재영(고려대학교); Ji Sung Shim(Korea University); Tae Il Noh(Korea University); Hong Jae Ahn(Korea University); 배재현(고려대학교)"
] | Malignant lymphoma of the bladder is a rare lesion, representing approximately 0.2% of the primary lesions and approximately 1.8% of the secondary lesions. A disseminated lymphoma presenting as a bladder mass is an infrequent phenomenon. The authors report the case of a 71-year-old patient with concurrent bladder lymphoma and bladder cancer presenting as metastatic bladder cancer. To the best of our knowledge, this is the first report of concurrent bladder lymphoma and bladder cancer. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000252.xml | ||
ART001689362 | oai_dc | Advances in Surgical Treatment of Male Infertility | Advances in Surgical Treatment of Male Infertility | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Hyo Serk Lee(Kwandong University); Ju Tae Seo(Kwandong University)"
] | A male factor is the only cause of infertility in 30% to 40% of couples. Most causes of male infertility are treatable, and the goal of many treatments is to restore the ability to conceive naturally. Varicoceles are present in 15% of the normal male population and in approximately 40% of men with infertility. Varicocele is the most common cause of male infertility that can be corrected surgically. In males with azoospermia, the most common cause is post-vasectomy status. Approximately 6% of males who undergo vasectomy eventually seek reversal surgery. Success of vasectomy reversal decreases with the number of years between vasectomy and vasovasostomy. Other causes of obstructive azoospermia include epididymal, vasal or ejaculatory duct abnormalities. Epididymal obstruction is the most common cause of obstructive azoospermia. Patients with epididymal obstruction without other anatomical abnormalities can be considered as candidates for vasoepididymostomy. With microsurgical techniques, success of patency restoration can reach 70∼90%. In case of surgically uncorrectable obstructive azoospermia, sperm extraction or aspiration for in vitro fertilization is needed. Nonobstructive azoospermia is the most challenging type of male infertility. However, microsurgical testicular sperm extraction may be an effective method for nonobstructive azoospermia patients. | 비뇨기과학 | null | http://dx.doi.org/ | kci_detailed_000252.xml | ||
ART001614190 | oai_dc | Laparoscopic Excision of a Congenital Seminal Vesicle Cyst and Coexisting Ipsilateral Renal Agenesis | Laparoscopic Excision of a Congenital Seminal Vesicle Cyst and Coexisting Ipsilateral Renal Agenesis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Yun Seok Jung(The Catholic University); 한창희(가톨릭대학교); Jang Ho Wee(The Catholic University); Jin Bong Choi(The Catholic University); Myung Sun Choi(The Catholic University); Seol Kim(The Catholic University); Jun Ho Sohn(The Catholic University); Joon Ho Lee(The Catholic University); 강성학(가톨릭대학교); 이용석(가톨릭대학교)"
] | Seminal vesicle cyst (SVC) with ipsilateral renal agenesis is a rare congenital anomaly. When the patient is symptomatic, surgical treatment may be necessary. The open surgical approach, traditionally considered the definite form of treatment, has been associated with a high rate of morbidity. The laparoscopic approach for the management of SVCs has recently been described. A 18-year-old man presented with a 2-year history of dysuria and perineal pain. The diagnostic evaluation revealed a 45×35×48 mm sized left seminal vesicle cyst. In addition, he had a solitary, right, functioning kidney, with left renal agenesis. Transperitoneal laparoscopic excision of the cyst was performed successfully. The patient was discharged from the hospital on the fourth postoperative day and did not present with any complaints or complications. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614054 | oai_dc | 외부 생식기의 손상 및 재건 | Trauma and Reconstruction of the External Genitalia | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김재헌(순천향대학교); 박재영(고려대학교)"
] | External genitalia trauma including penis and scrotum often accompanies with genitourinary trauma or occurs independently, especially in male. External genitalia trauma is an emergent and serious condition like urinary system trauma but it has been unnoticed in urologic field. The treatment of external genitalia trauma is diverse according to the nature of trauma and injured anatomic site. The classification of trauma is important because it impacts the method of treatment however there has been no universe description about the classification of external genitalia trauma. The aim of this article is to summarize the methods of repairing defect in the penis and scrotum and the clinical application to the reparative treatment according to classification by its nature of injury. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614056 | oai_dc | 부부갈등으로 인한 별침에 대한 태도의 성차 | Gender Differences in Attitudes Towards “Sleeping in Separate Rooms” in Response to Marital Conflict | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박진희(제주대학교); 윤가현(전남대학교)"
] | Purpose: The purpose of this study was to determine gender differences in attitudes towards sleeping in separate rooms (SSR) a means of dealing with marital conflict and to explore the reasons why participants agreed or disagreed with SSR.
Materials and Methods: Research participants were 616 married people (300 men, 316 women) aged 30 to 89 years and currently lived with their spouses in the same house. They were asked to assess their attitudes towards SSR using a Likert scale from 0 (strongly disagree) to 10 (strongly agree). Two separate SSR questions were given to them: one for the respondents themselves and the other for couples in general.
Results: There were significant gender differences in attitudes towards SSR. Men generally disagreed with SSR, with a negligible difference between the two separate SSR cases (p＞.05). However, women agreed with SSR, especially with the question about the respondents themselves (p＜.01). The most frequent reason from agreeing with SSR was to alleviate conflict, while the most frequent reason for disagreeing was related to sexual issues, which showed significant gender differences.
Conclusions: Gender differences in attitudes towards the SSR were found, and the differences were examined in the context of social exchange theory. The limitation of this study was that the sexual interactive and communicative patterns of the couples who were sleeping in separate rooms were not explored. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614199 | oai_dc | Life-Threatening Hypovolemic Shock after Transrectal Ultrasonography Guided Prostate Biopsy: Treatment with Selective Arterial Embolization | Life-Threatening Hypovolemic Shock after Transrectal Ultrasonography Guided Prostate Biopsy: Treatment with Selective Arterial Embolization | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"신홍석(대구가톨릭대학교); Young Hwan Lee(Catholic University of Daegu)"
] | Rectal bleeding is a frequent finding in patients after transrectal ultrasonography (TRUS)-guided prostate biopsy but is usually mild and stops spontaneously. We report herein a case of life-threatening hypovolemic shock due to rectal bleeding after TRUS-guided prostate biopsy that was successfully treated by selective arterial embolization. The aim of this report is to share our experiences of the management of massive rectal bleeding after prostate biopsy. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614105 | oai_dc | 하부요로증상을 지닌 전립선 크기가 작은 환자에 있어서의 요역동학적 검사 결과 | Urodynamic Findings in Patients with Lower Urinary Tract Symptoms and Small Prostate Volumes | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"최진봉(가톨릭대학교); 김세웅(가톨릭대학교); 조혁진(가톨릭대학교); 홍성후(가톨릭대학교); 이지열(가톨릭대학교); 황태곤(가톨릭대학교)"
] | Purpose: Lower urinary tract symptoms (LUTS) can be caused by abnormal detrusor activity, bladder outlet obstruction (BOO), or numerous other factors. These factors must be evaluated with scrutiny, especially when prostate volume is small and the patient is about to have invasive treatment. We evaluated the urodynamic findings of patients with LUTS and small prostate volumes.
Materials and Methods: From January 2006 to December 2008, a total of 140 men with LUTS underwent urodynamic study. Of these 140 men, 51 patients with prostate volume ≤30 ml and an International Prostate Symptom Score (IPSS) ≥8 were evaluated.
Results: The average age of the patients was 65.5±7.4 years (range 46∼86), mean prostate volume was 24.5±5.1 (range 13.0∼30.0), mean IPSS was 15.5±7.7 (range 8∼34), and quality of life (QOL) score was 3.4±1.5 (range 3∼6). BOO was the most common finding, affecting 21 (41.2%) patients. The patients with BOO were significantly older than the unobstructed patients (70.1±5.9 and 62.4±6.7 years, respectively; p＜0.001) and had larger prostates (27.5±3.1 and 22.4±5.1, respectively; p＜0.001). Furthermore, they had higher IPSS, but the difference was not significant (p=0.074). Eighteen (35.5%) patients had normal findings, while detrusor underactivity (DU) was found in 15 (29.4%) and detrusor overactivity (DO) in 3 (5.9%) patients. There was no significant difference in age, prostate volume, or IPSS between men with and without DU.
Conclusions: The most common finding of LUTS with small prostate volume is BOO, even though it accounts for less than half of the patients. However, patients with normal finding or DU on urodynamic study account for majority of cases, emphasizing the value of urodynamic study before invasive treatments. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614136 | oai_dc | Comparison of Different Alpha-blocker Combinations in Male Hypertensives with Refractory Lower Urinary Tract Symptoms | Comparison of Different Alpha-blocker Combinations in Male Hypertensives with Refractory Lower Urinary Tract Symptoms | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Keon-Cheol Lee(Inje University); 조인래(인제대학교); Jong Gu Kim(Happy Urology Clinic); Sung Yong Cho(Inje University); Joon Sung Jeon(Inje University)"
] | Purpose: We compared the efficacy and safety profiles of dose increase, traditional combination methods, and combining different alpha blockers in hypertensive males with lower urinary tract symptom (LUTS) refractory to an initial dose of 4 mg doxazosin.
Materials and Methods: Between 2000 and 2005, 374 male patients with LUTS and hypertension unresponsive to 4 weeks of 4 mg doxazosin were enrolled. The subjects were randomly classified into 3 groups, 8 mg/day of doxazosin (D group), 4 mg of doxazosin plus 0.2 mg/day of tamsulosin (DT group), and 4 mg doxazosin plus 5 mg/day finasteride (DF group). Patients were evaluated based on their International Prostate Symptom Score (IPSS), quality of life (QOL), uroflowmetry and blood pressure (BP) and adverse events (AEs) at the baseline and 3 and 12 months after treatment.
Results: The 269 patients (71.9%) were followed for at least 1 year (D group n=84, DT group n=115, and DF group n=70). The clinical parameters before and after initial 4 mg/day doxazosin were not different among the 3 groups. IPSS improvement after 3 months and maximal flow rate (Qmax) improvement after 3 and 12 months were significantly higher in the D and DT groups than the DF group (p＜0.05). Sitting systolic and diastolic BP of the D group decreased larger than those of the other 2 groups (p＜0.05). At least one of the AEs was reported by 29.0%, 19.3%, and 17.3% of patients in the D, DT, and DF groups, respectively. In particular, vasodilatory AEs of the D group (28.2%) were higher than those of other groups (p＜0.05), and sexual function AEs of the DF group (10.9%) were higher than those of other groups (p＜0.05).
Conclusions: Doxazosin 4 mg plus tamsulosin 0.2 mg has comparable efficacy but less vasodilatory AEs than doxazosin 8 mg, and has superior efficacy to but comparable vasodilatory AEs to 4 mg doxazosin plus 5 mg finasteride in hypertensive male LUTS patients. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614090 | oai_dc | Efficacy and Safety of Biodegradable Microparticles in the Regeneration of Injured Rabbit Corpus Cavernosum: Primary Report | Efficacy and Safety of Biodegradable Microparticles in the Regeneration of Injured Rabbit Corpus Cavernosum: Primary Report | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Young Joon Kim(Ewha Womans University); 정우식(이화여자대학교); Sung Joo Lee(Ewha Womans University); 윤하나(이화여자대학교); Jeoung Yong Kim(Kangseo Songdo Hospital); Mi Jung Shin(REGEN Biotech); Won Hwa Kang(REGEN Biotech); Gun Poong Kim(REGEN Biotech)"
] | Purpose: This study analyzed the effectiveness of poly (lactic-co-glycolic acid) (PLGA) as a tissue recovery agent and determines the in vivo safety and efficacy of microparticle-based PLGA.
Materials and Methods: Fifteen 3-month-old male white rabbits were used. Allogenic adipose tissue derived stromal vascular fraction (SVF) was cultured and labeled with the fluorescent dye PKH26. The rabbits were divided into 4 groups: the SVF group, the PLGA group, the normal control group, and the disease control group. The right corpus cavernosal tissue of the rabbits was surgically removed in the selected portion, except in the normal control group. The defect space of each rabbit was replaced with 106 SVF cells in the SVF group and 0.1 g of biodegradable polymer solution in the PLGA group. Microscopic confirmation and analysis of tissue regeneration were performed after 8 weeks. Using confocal microscopy, the nuclei of the smooth muscle cells and SVF migration were examined. The composition of smooth muscle and fibrosis of the injured corpus cavernosum were compared and analyzed by Masson’s trichrome stain.
Results: There were no signs of migration or rejection of the injected materials in any of the experimental groups. The mean amount of smooth muscle in the normal control group was 15.25±1.34μm^2 (right) and 13.90±0.703μm^2 (left); in the disease control group it was 11.10±0.87μm^2 (right) and 12.80±1.01μm^2 (left); in the SVF group it was 13.82±4.10μm^2 (right) and 13.96±3.94μm^2 (left); and in the PLGA group it was 12.89±1.39μm^2 (right) and 13.24±1.43μm^2 (left). Only the disease control group showed significant decreased smooth muscle in the left cavernosum (p＜0.05). No significant difference was found between the left and right side of each rabbit’s cavernosal smooth muscle in the SVF or PLGA group (p＞0.05). Furthermore, no difference was found between any two groups (normal control versus SVF (p=0.705), normal control versus PLGA (p=0.88), SVF versus PLGA (p=0.23).
Conclusions: PLGA microparticles had the same tissue restoring effect when compared with SVF and no adverse effect or migration of particles was found through the injection of PLGA or SVF. PLGA is safe and has the proper tissue recovery effect, saving additional tissue harvesting. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614079 | oai_dc | 병무청자료로 분석한 우리나라 젊은 남성에서의 비뇨기계 질환의 빈도 | The Prevalence of Urologic Disease in Young Men Based on a Review of Korean Military Conscription Examination Results | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"송필현(영남대학교); 문기학(영남대학교); 권상택(경남지방병무청); 김현태(영남대학교)"
] | Purpose: We aimed to elucidate the prevalence of urologic disease in young men by reviewing the results of military conscription examinations in the Republic of Korea.
Materials and Methods: The results of 615,382 conscription examinations undertaken by the military manpower administration offices in Seoul, Korea from January, 2006 to December, 2007 were reviewed. The physical examinations were conducted based on the Ministry of National Defense implementing ordinance No. 590.
Results: Twenty eight hundred fifty-three (0.46%) examinees were found to have urologic diseases, among which urinary tract infection was the most frequent (0.16%) single disease entity, followed by testicular absence (0.12%), single kidney (0.05%), varicocele (0.04%), urolithiais (0.03%), and cryptorchidism (0.01%). Among the 16 examinees with penile amputation, 15 had been surgically amputated due to gender identity problems.
Conclusions: With modifications of the Korean conscription examination and long-term evaluation, its results could help elucidate the prevalence of urologic diseases in young males in Korea. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614062 | oai_dc | 혈정액 환자에서 경직장초음파촬영술의 유용성과 5알파-환원효소억제제의 치료효과 | Clinical Significance of Transrectal Ultrasonography and Efficacy of Dutasteride Treatment in Patients with Hemospermia | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김영중(전남대학교); 박광성(전남대학교); 황의창(전남대학교); 김선옥(전남대학교); 정승일(전남대학교); 강택원(전남대학교); 권동득(전남대학교); 류수방(전남대학교)"
] | Purpose: The aims of this study were to investigate the clinical significance of transrectal ultrasonography (TRUS) and the efficacy of dutasteride (5α-reductase inhibitor) in patients with hemospermia.
Materials and Methods: From January 2005 to December 2008, 60 patients with hemospermia were enrolled in the study. All patients underwent a digital rectal examination and TRUS; serum prostate specific antigen was also measured. The management of hemospermia was one of the following: watchful waiting, dutasteride treatment, or antibiotics with dutasteride.
Results: Thirty-four patients (56.7%) had positive findings on TRUS. There were 16 cases (26.7%) of prostate calcification, 13 cases (21.7%) of ejaculatory duct cyst, 3 cases (5%) of ejaculatory duct calcification, a case of seminal vesicle inflammation, and a case of ejaculatory duct dilation. Dutasteride treatment resulted in improvement of symptoms in 87.9% (29/33) of the cases, whereas treatment with antibiotics or antibiotics with dutasteride resulted in a 100% (6/6) success rate. However, among 14 watchful waiting patients, only 3 patients (21.4%) showed an improvement of symptoms.
Conclusions: This study showed that TRUS is an easy and effective method for the assessment of hemospermia, and also revealed that dutasteride could be a useful agent in the treatment of hemospermia. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614116 | oai_dc | 하부요로증상/전립선비대증의 치료에서 12개월 이상 알파차단제와 항콜린제를 병용투여하였던 환자들의 치료 경험 | Experience of Combination Therapy with Alpha Adrenergic Receptor Antagonist and Anticholinergic Agent in Patients with Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia: 12 Month Follow-up | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"서유미(단국대학교); 김형지(단국대학교)"
] | Purpose: Through more than 12 months of follow-up, the efficacy and safety of combination therapy with alpha adrenergic receptor antagonist and anticholinergic agent was investigated retrospectively.
Materials and Methods: This study retrospectively analyzed the data of 84 patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) who were managed with an alpha adrenergic receptor antagonist and anticholinergic agent for at least 12 months between Jan 2007 and Dec 2010. On patients’ first visit to our department, we obtained the patients' demographic data and information about the prostate total volume, serum prostate specific antigen (sPSA), maximum urinary flow rate (Qmax), International Prostate Symptom Score (IPSS), and postvoid residual (PVR) of each patient. After 12 months, changes in the above factors and the side-effects of anticholinergic agents were investigated.
Results: The mean age of the patients was 66.1 years and the total observation period after drug administration was an average 20 months; the total sPSA and prostatic volume of patients was 1.8±0.8 ng/dl and 37.3±9.5 g, respectively. Qmax in uroflowmetry was improved after 12 months of medication (changed from 9.0±3.4 to 13.8±4.5 ml/sec; p＜0.001). PVR was increased from 35±22.2 ml to 49.3±37 ml (p＜0.001), but the change was not clinically significant, and no acute urinary retention occurred. The total IPSS score decreased from 21.4±5.1 to 13.3±4.6 (p＜0.001), the storage score of IPSS decreased from 9.8±2.4 to 5.6±2 (p＜0.001), and the voiding score was decreased from 11.6±3.7 to 7.7±3.2 (p＜0.001). The QoL with IPSS was improved from 4.2±0.8 to 2.8±0.7 (p＜0.001). During the 12 months there were 34 patients (56 cases) of adverse events. However, no serious adverse events were reported.
Conclusions: Combination therapy with alpha adrenergic receptor antagonist and anticholinergic agent was safe and made an improvement in LUTS in patients with BPH and storage symptoms. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614049 | oai_dc | 남성갱년기의 운동 | Physical Activity and Exercise for Men with Late Onset Hypogonadism | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"최호천(서울대학교); 조비룡(서울대학교); 오범조(서울대학교); 김현수(서울대학교)"
] | Late onset hypogonadism (LOH, also referred to as age-associated testosterone deficiency syndrome, TDS) is a clinical and biochemical syndrome associated with advancing age and characterized by symptoms and a deficiency in serum testosterone levels. It may result in a significantly reduced quality of life and adversely affect the function of multiple organ systems. Although the treatment of LOH is primarily based on hormone replacement, other treatment modalities (medical or non-medical treatment) can also be considered for various accompanying symptoms. The efficacy of exercise in the treatment of LOH has already been evaluated in several studies, and many of them show beneficial effects for some specific symptoms and diseases. This study was designed to evaluate the relationship between exercise and plasma testosterone levels, and the potential beneficial effects of exercise for each specific symptom of LOH, and finally to consider the appropriate exercise treatment for LOH. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001614071 | oai_dc | 페이로니병의 치료에서 Potassium Aminobenzoate의 초기 경험 | Effect of Potassium Aminobezoate in Oral Therapy for Peyronie’s Disease: Preliminary Study | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"함병국(고려대학교); 문두건(고려대학교); 박종진(고려대학교); 노태일(고려대학교); 김상우(고려대학교); 박태용(고려대학교); 안순태(고려대학교); 오미미(고려대학교)"
] | Purpose: To evaluate the effect and improvement of potassium aminobenzoate (500 mg Peyron capsule) in oral therapy for Peyronie’s disease.
Materials and Methods: From February 2011 to September 2011, 31 patients with Peyronie’s disease received potassium aminobezoate (500 mg Peyron capsules) and were divided into two groups. Group 1 (N=10) received potassium aminobezoate (500 mg Peyron capsule) 3 g four times daily without previous treatment of Peyronie’s disease, while group 2 (N=21) received the same drug with previous treatment of Peyronie’s disease (10 mg Tamoxifen＋300 mg L-carnitine two times daily). Outcomes were assessed by subjective symptom change, pain relief, resolutions of the plaque, and curvature.
Results: After 3 months, there were no significant improvements in clinical outcomes of either group and among all the patients, 23 stopped taking potassium aminobezoate (23/31, 74%). The reasons for ceasing the therapy were gastrointestinal trouble (8/23, 35%), too many doses to take (7/23, 30%), ineffectiveness (6/23, 26%), and high price (2/23, 9%).
Conclusions: Athough the etiology of Peyronie’s disease has not been elucidated, potassium aminobenzoate in therapy of Peyronie’s disease has been used. The use of this medication has the limitations of gastrointestinal trouble, ineffectiveness, too many doses, and high price. Further evaluations of the effect and appropriate dosing of potassium aminobenzoate are needed. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001581069 | oai_dc | Factors Associated with the Timing of First Sexual Intercourse Among College Students in Busan, Korea | Factors Associated with the Timing of First Sexual Intercourse Among College Students in Busan, Korea | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김영혜(부산대학교); 윤은영(부산대학교병원); 박남철(부산대학교); 박현준(부산대학교)"
] | Purpose: The purpose of this study was to predict when college students in Korea have their first sexual intercourse and to explore the factors associated with the timing of first sexual intercourse.
Materials and Methods: Data are collected by using self-report survey toward total 797 of male and female college students who are currently attending the college in Busan, Korea. Students were divided by four groups according to their age of timing of first sexual intercourse, ＜16 years, between 16 to under 19, over 19 years and non-experienced. To examine the difference of four groups, Chi-square test and ANOVA (analysis of variance) were used. For estimation of the timing of first sexual intercourse we used Kaplan-Meier estimation and for differences of each group we used log-rank test. To identify the factors associated with the timing of first sexual intercourse we used Cox proportional hazards model.
Results: 41.4% of college students have experienced sexual intercourse. Of four groups the early sexual intercourse group (＜16 years) had high rate of cigarette smoking, alcohol drinking, drug use, open sexual attitude, and a high number of sex partner. The factors associated with the timing of first sexual intercourse among college students was identified male, open parents attitude about sex, pornography experiences, cigarette smoking, alcohol drinking.
Conclusions: This study predicts the timing of first sexual intercourse among college students in Korea. Early sexual debut is an important indicator for continued risk behavior regarding reproductive health. | 비뇨기과학 | null | kci_detailed_000252.xml | |||
ART001581111 | oai_dc | 음낭 및 회음부에 발생한 낭종성 림프관종 | Cystic Lymphangioma of the Scrotum and Perineum | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"송필현(영남대학교); 문기학(영남대학교); 김종민(영남대학교); 양소전(영남대학교); 최지웅(영남대학교); 김미진(영남대학교); 김현태(영남대학교)"
] | Cystic lymphangiomas are a benign tumor caused by lymphatic malformation. They are normally seen in the head and neck region and very rarely occur in the scrotum. We report a rare case of a 20-year-old man who presented with a gradually enlarging, painful scrotal mass which was identified ultrasonographically and histologically as a scrotal cystic lymphangioma and treated by surgical excision. | 비뇨기과학 | null | kci_detailed_000252.xml |
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