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C How much am I exposed? Exploring public perceptions of EMF exposure from mobile communication technology and 5G B32 FB01 Sarah Link1, Marie Eggeling1, Ferdinand Abacioglu1, Christoph Böhmert1 1IU International University of Applied Sciences A B D E1 E2 F1 F2 G H I1 I2 RESULTS: Base Station Siting Initially, most participants (n=32) chose a location outside the village (locations 1, 3, 5, 6) A relative majority of participants (n=16) selected location 3 on the factory building Arguments for the initial choice: Distance from the reference point (n=13) Aesthetic aspects (n=12) Reception (n=8) Radiation only played a role in the choice of location for three participants After informing participants that for regular MP users individual exposure increases with increasing distance to a BS, about half (n=8) of those initially choosing a remote site (locations 5/6) changed to a location closer to the reference point. “I would then perhaps change to location 3. Well, [...] I didn't know that the transmission power would be correspondingly higher.” (male, 42, city) RESEARCH AIMS 1st Aim: Investigate in which situations lay people feel particularly exposed to EMFs emitted by MC/5G. 2nd Aim: Learn about people’s preferences for the siting of 5G emitting base stations, and about the reasons for these preferences. RESULTS: Exposure Perception Situations in which BSs were central were associated by 20 participants with a higher personal exposure than the mobile phone (MP) situations As reasons for their assessment participants referred to the BS as “abstract”, “the common enemy”, “hostile” or “ugly”. The MP, on the contrary, was perceived as “kind”, “familiar” or “something one enjoys”. A higher number of BS antennas was associated with a higher exposure For MPs 10 participants associated a higher number of distant devices with a higher exposure level than one close device The closer the mobile device is to sensitive body parts (head, reproductive organs), the higher the situation tended to be ranked 23 participants ranked at least one of the situations (phone call, phone in pocket) prior to an other MP situation For BS EP, participants tended to rank the 5G prior to the 4G situation (n=21) No relevant difference between Wi-fi, 4G, and 5G situations regarding MP EP Lay People’s Exposure Perception Quantity Data transfer Antenna vs. Phone Proximity to particular body parts Distance Duration Visibility Location Network type Change 4G 5G METHODS Structure: 35 individual interviews + 6 focus groups Sample: 18f/17m, mean age: 39y (range 18-67y) Variables assessed: sociodemographic variables, exposure perception (EP), base station (BS) siting preferences, further variables (see handout) Interactive tasks: Ranking task: Participants had to rank situations (see fig. 2) according to their EP Base station siting task: Participants had to select a BS site in a fictious scenario (see fig. 3) CONCLUSION Exposure to EMF is a subordinate factor influencing site selection and negative attitudes towards BS No evidence that 5G is evaluated / perceived significantly different than previous MC standards CONTACT Sarah Link, sarah.link@iu.org DISCUSSION Siting preferences are influenced by many factors EP depends on a variety of factors similar to other EMF sources (e. g., power lines) Dimensions and EP EP is higher for BS than for MP Proximity and quantity play a rather important role Network type seems to be irrelevant for MP EP Limitations: No complete variation of dimensions within the situations Difficult to attribute EP / results of the ranking task to a single criterion (such as 5G reception) Site selection partly in the interest of multiple stakeholders (not only related to reference point) Findings will be used to implement a quantitative online survey in multiple European countries Figure 1: Dimensions possibly affecting exposure perception Figure 2: Exposure situations used in the ranking task Figure 3: Results of the | poster |
https://webappsx.ugent.be/eventManager/events/DigitisingtheHumanitiesPleaseregisterhere Contactjulie.birkholz@ugent.beannemieke.romein@ugent.bettps://www.ghentcdh.ugent.be/dhresearchlabUniversiteitGent@ugent; @ghentcdhBringing transcriptions together –Transcription Network BE/NLThisjoint effort fromDutch and Belgium institionsis (soontobe) launchedtogathertranscriptionsand photo’sof archivalmaterialin Dutch. These couldbeusedtocreatemore genericmodelstobeabletodecyphertextsmore quicklyor buildmodelsforspecificeras. Ifyouhappen tohave or knowpeoplewhohave transcriptionsin Dutch fromanyperiod, do nothesitatetocontact Annemieke whocaninformyoufurther. The Dutch National Archivewillsupport thisproject witha part-timecoordinatorthatwillassist withfaciliatingtheuseof automatic transcritpionsoftwaresand platforms foranyresearch usingDutch languagemanuscripts. Workshops and training willalsobecoordinatedthroughtheDutch National Archive.The Scantentis a useful aid to scan documents with your phone (especially with the Android DocScan-app) | poster |
Sum Rear Tire Front Tire Lat. Acc + Yaw Rate Roll Acc. Roll Rate unstable stable Analysis of High speed instability of Weave Mode in Motorcycle by Using Energy Flow Method Hirotaka TAMOTO1, Tetsuya KIMURA1, Masayuki MIKI1, Tsuyoshi KATAYAMA2 1Fundamental Technology Research Division, YAMAHA MOTOR CO., LTD. Shizuoka, Japan 2New Mongol Institute of Technology, Ulaanbaatar, Mongolia Bicycle and Motorcycle Dynamics 2019 Symposium on the Dynamics and Control of Single Track Vehicles, 9 – 11 September 2019, University of Padova, Italy Degree of freedom in weave mode Real part of eigenvalue ∝1/m Imaginary part of eigenvalue ∝1/√m Characteristics of damped vibration system Equation of motion m 𝒙+ 𝒄 𝒙+ 𝒌𝒙= 𝟎 m 𝒄 𝒌 Eigenvalue 𝝀= −𝒄± 𝒄𝟐−𝟒𝒎𝒌 𝟐𝒎 Given the vibration system with one degree of freedom, Which degree of freedom is the weave mode? X Component : Proportional to real part of eigenvalue Y Component : Proportional to imaginary part of eigenvalue Eigenvector ×Coefficient 𝑋= 𝑦 𝜓 𝜙 𝛿 𝑌𝑓 𝑌𝑟 Eigenvectors normalized with yaw rate (Mf k2 +Irz + Ifx sin2ε+ Ifz cos2ε) 𝜓= - Mf k 𝑦1 -｛Mf jk-Crxz + (Ifz-Ifx)sinεcosε｝ 𝜑 -(Mf ek+Ifz cosε) 𝛿+｛ify/Rf+(iry+λi)/Rr｝ 𝑥1 𝜑 - Mf k 𝑥1 𝜓+ ify/Rf sinε 𝑥1 𝛿+ l1 Yf –l2 Yr Yaw system equation Unit vector of yaw rate The contribution to the stable direction of Sum ⇒Larger at 120km/h than at 200km/h Damping ratio (Real part) Frequency (Imaginary part) Only the Yaw system almost matches ! Main freedom of weave mode is Yaw system m 𝒙= −𝒄 𝒙−𝒌𝒙 ×1.1 Rear tire force that most affects the stability of the weave mode. The main reason why the rear tire force decreases is a phase delay. Cause of the phase delay is the decrease of the Yaw Rate coefficient. Main factor of the decrease in the Yaw rate coefficient is the increase in the vehicle speed. X-component divided Into Tire and Body X-component divided into Front tire and Rear tire 【Analysis using the Yaw system equation】 【Analysis using the Rear tire equation】 The change of Phase and Magnitude Sum Yaw Rate Lat. Velo. unstable stable The cause is CYs2 or 𝒙1 120km/h 200km/h Rate of change [%] 120.00 200.00 166.67 3.34E+03 3.65E+03 109.07 𝒙 1 CYs2 ※l2 is unchanged Change rate of CYs2 and 𝒙1 Main factor! Yr = －CYs2/ 𝑥1 𝑦1 ＋CYs2l2/ 𝑥1 𝜓＋CYc2φ Rear tire equation Lat. Velo. Yaw Rate Roll Angle Main cause Energy Flow Method (EFM) Analysis result Summary Introduction In this report, we investigate the cause of the decrease in the stability of weave mode in high speed region using Energy Flow Method. Rear tire gives most influence on the weave mode In Front and Rear tire, the ratio of Rear tire is larger The main factor determining stability is Energy Flow of tire Most of the breakdown of change is the delay in the Phase of the Rear tire Yaw Rate ⇒Reduction of coefficient Main factor of the decrease in the Yaw rate coefficient is the increase in the vehicle speed | poster |
An efficient, tunable solution for pre-capture multiplexing in targeted sequencing via novel chemistry and semiconductor DNA synthesis technology Irene Song, Raymond Miller, Jiashi Wang, Jianpeng Wang, Long Fan, Lumeng Ye, Hong Li, Heidi Huang Oligo Department, GenScript USA Inc., 860 Centennial Ave., Piscataway, NJ 08854 GenScript Tunable target enrichment by semiconductor technology GenScript CMOS Semiconductor electrochemistry T T T T TT T T T T TT Deprotected Amidite Electrochemical deblocking Electrode activated Electrolyte Solution Acidic Environment T T T T TT T T T T T T AAAAAA A A A A A A A Amidite Solution Coupling T T T T T T T T T T TT AAAAAA Wash Figure 3. GenScript used Semiconductor DNA Synthesis platform a) GenScript-CustomArray CMOS semiconductor chip b) Electrochemical synthesis of DNA oligo in transient micro-reactors c) NGS analysis concludes 99.7% coverage. Interdecile # < 2.5 Semiconductor technology offers a fast and cost-effective way to synthesize capture probes panel for target enrichment. Moreover, since the sequence and abundance of each probe on the chip can be precisely controlled, the panel performance can be evolved based on NGS data feedback. Figure 4. Comparison of semi-conductor based dsDNA hybridization probe panel with column-based ssDNA probe panel. ~8000 120nt probes covering a 600kb target region. Figure 5. Comparison of different technology. Semiconductor chip synthesized GenFisher custom hybridization probes panel provides better capture efficiency compared to other vendors’ panels using single-stranded DNA, RNA or inkjet synthesized double-stranded DNA. All data are average of two independent technical replicates. a b c Simplified pre-capture target enrichment workflow with TRUE Universal blockers 0% 20% 40% 60% 80% 6nt 8nt 10nt On Target Rate Universal Blocker Performance Universal blockers by novel chemistry To enable the maximum pooling potential of targeted NGS libraries, here we introduce a novel design and chemistry to hybrid capture blockers, an essential component in the experimental workflow to block the permissive interactions between library adapters and target probes, and adapters themselves, both of which lead to wasteful sequencing. The conventional blockers, whose sample index-matching portion uses either degenerate bases or universal pairing bases, depends on the length of the sample index for the libraries, dramatically impeding the flexibility of index-blockers pairing. Our new invention, GenFisher Universal Blockers, create a novel solution to the annealing between sample indexes on libraries and blockers regardless of the index length. Figure 6. GenFisher Universal blocker makes pre-capture pool easier a)GenFisher Universal Blocker uses novel chemistry to block indexes of different lengths. b)Hybridization capture by GenFisher Hybridization kit and Universal Blockers show similar on target rate regardless of index length c)1-plex vs 8-plex pre-capture pooling with and without Universal Blockers. Multiplexing has no effect on the efficiency of blockers. a) b) c) www.genscript.com 860 Centennial Ave., Piscataway, NJ 08854, USA Toll-Free: 1-877-436-7274 Telephone: 1-732-885-9188 Fax: 1-732-210-0262 Email: Irene.Song@genscript.com Figure 1. GenFisher 16hr Hybridization kit is compatible with both dsDNA probe and ssDNA probes. 1hr fast hybridization kit allows 1 day workflow for library preparation and target enrichment without compromising capture efficiency. All data without considering flanking regions when calculating on-target %. 50.00% 52.00% 54.00% 56.00% 58.00% 60.00% 62.00% 8-plex 12-plex 16-plex 24-plex Pre-capture pooling with GenFisher hybridization kit On target base % 56.1% 49.5% 36.7% 66.0% 66.6% 55.5% 0.0% 20.0% 40.0% 60.0% 80.0% Competitor W Competitor X Competitor Y GenScript Competitor Z GenFisher Hybridization kit 16hr On target base % High compatibility hybridization and wash kit with 24-plex pre-capture pooling Figure 2. GenFisher Hybridization kit | poster |
II Poster No. A-5 National Aeronautics and Space Administration Jet Propulsion Laboratory California Institute of Technology Pasadena, California www.nasa.gov Copyright 2015. All rights reserved. National Aeronautics and Space Administration Herschel Galactic plane survey of ionized gas traced by [NII] [ ] plays a significant role in star formation as it is produced only in ionized regions; in HII regions as well as diffuse ionized gas. The ionization potential of nitrogen (14.5 eV) is greater than that of hydrogen (13.6 eV), and carbon (11.3 eV), therefore the ionized nitrogen [NII] lines reflect the effects of massive stars, with possible enhancement from X-ray and shock heating from the surroundings. Motivation Results [NII] has two fine structure transitions at 122 and 205 µm. The two lines can be used to calculate the electron density and column density of N+, if one assumes that the emission from both transitions originate in the same gas and under roughly uniform conditions. [NII] detections are mainly toward the Galactic center. [NII] electron densities are found to be between 10 to 50 cm-3 (Fig. 2) and N+ column densities range between 1016 to 1017 cm-2. High densities indicate that the source of the emission is not the WIM (Warm Ionized Medium), which has densities 10-100 times smaller. Far infrared and sub-/millimeter atomic & ionic fine structure and molecular rotational lines are powerful tracers of star formation. Although CO lines trace cool to moderately warm molecular gas, ionized carbon [CII] produces the strongest lines, which arise from almost all warm (T >35 K) parts of the ISM. However,[CII] alone cannot distinguish fully ionized gas from weakly ionized gas. Methods Two far-infrared 122 µm and 205 µm [NII] fine structure spectral lines are observed via Photodetector Array Camera and Spectrometer (PACS) onboard Herschel Space Observatory. The sample consists of 149 lines-of- sight (LoS) positions in the Galactic plane, following those of the [CII] 158 µm observations obtained with the GOT C+ survey. PACS data have 5x5 spatial pixels therefore all 25 spectra are averaged to improve S/N, and that led to increase the number of detections in the averaged spectra. [CII] is the most important coolant of atomic hydrogen clouds and the photon dominated regions (PDRs) of molecular clouds and is widely used as a tracer of star formation. We found that [NII] measured with HIFI as well as PACS are linearly correlated with the [CII] emission. Fig 3: Position vs. intensities of [NII] and [CII] are shown through the Galactic plane. Fig 4: [NII] vs [CII] intensities shows tight correlation. Fig 2: Electron densities are shown as function of the position in the Galactic Plane. Galactic longitude (l) log I (W m-2 sr-1) # of LoS Int Ratio n(e) = 100 cm-3 n(e) = 50 cm-3 n(e) = 10 cm-3 n(e) = 1 cm-3 [NII] Fig 1: Histogram of intensities [NII] emission is highly correlated with that of [CII], implying that between 1/3 and 1/2 of the [CII] emission arises in the ionized gas. Possible origin of the observed [NII] include the ionized surfaces of dense atomic and molecular clouds, the extended low density envelopes of HII regions, and low-filling factor high-density fluctuations of the WIM. The pixel to pixel variation of the emission within a single Herschel pointing is relatively small, which is interpreted as the [NII] emission comes from an extended gas. N [NII] detections are mainly toward the Galactic center (intensity distribution shown in Fig. 1), but the opposite side of the Galactic center gives upper limits of ~4x10-10 W/m2/sr-1 for the 122 µm line and ~2x10-9 W/m2/sr-1 for the 205 µm line (Fig. 3). Principal Investigator: Umut Yildiz (3266) Paul Goldsmith (3266), William Langer (3200), Jorge Pineda (3266) It is important to quantify what fraction of [CII] emission arises in the ionized gas, to resolve the different parts of the ISM, leading to determine the total mass of the ISM. | poster |
Conclusion Outlook Introduction In materials science, the understanding of new materials is becoming increasingly complex. Without suitable data managing concepts, it will no longer be possible to handle the constantly growing amounts of data generated from simulations and experiments. The Karlsruhe Data Infrastructure for Materials Science (Kadi4Mat)[1] therefore presents a research data infrastructure that aims to resolve these challenges while taking the FAIR data principles[2]into account. Its functionalities can be summarised as a repository and an electronic lab notebook. Kadi4Mat Functionalities Kadi4Mat presents an ecosystem that encompasses different modules –Repository,Electronic Lab Notebook,Workflows,Ontologies, Machine Learning– which in sum create a FAIR research data infrastructure. Through its REST-API Kadi4Mat further offers defined interfaces for connecting it to other systems, allowing for the simple extension of the available functionalities. lars.griem@kit.edu www.iam.kit.edu/cms References [1] Brandt, Nico et al. Data Science Journal, vol. 20, 2021, p. 8. [2] Griem, L, et al. Data Science Journal, vol. 21, 2022, p. 16. [3] Sangya Pundir / CC BY-SA 4.0 KIT – The Research University in the Helmholtz Association Automated Documentation of Research Processes Using RDM L. Griem 1, R. Thelen2, M. Selzer 1 1Institute of Nanotechnology (INT-MSS), Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany 2Institute of Microstructure Technology, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany Ecosystem Micro gear Job ticket Green job ticket Batch number: 04552 602 Editor: see above Page: 1 of 2 IFA-Number: 11-935F-01F Provided parts, masks etc.: Manufacturing item: Object number: 05841 See FS02 Micro gear for demonstration Customer: Mustermann lfd.- Production process Specifications Amount Finished No. Production & test steps (e.g. AA, PA, Text etc.) in out Name, Date 1. Create job ticket and folder AA605.xx --- --- (MF-FVB) 2. Obtain job ticket and all provided parts AA605.xx (GL-FAF) 3. Take substrates of type SP403009.xx for the batch numbers: 1.) Batch No.:__________________ 2.) Batch No.:__________________ 3.) Batch No.:__________________ 4.) Batch No.:__________________ from the clean room storage and mark the wafer box. AA619.xx 4 4. Vapour deposition of metallic layers. AA653.xx Cr-Thickness: 5nm Au-Thickness: 15nm Current Documentation Implementation Automated Documentation The FAIR management of research data is undoubtedly an important step in accelerating scientific work. However, a significant part of knowledge often lies not in the research data itself, but in the processes that led to its creation. Therefore, the research data infrastructure Kadi4Mat [1] provides, in addition to a data repository, a workflow editor [2] for process documentation and automisation. In combination, these modules allow the automated and FAIR documentation of scientific processes and the data generated within them. The implementation of such an automated documentation is illustrated through the example of the experimental production of microstructural components at the Institute of Microstructure Technology of the KIT. Introduction Conclusion Integrating the job ticket documentation into the research data infrastructure Kadi4Mat offers many benefits. The job tickets can be quickly searched for specific parameters, equipment or processing facilitating the development of new production processes. Additionally, the user is interactively guided through the manufacturing process in the workflows. This not only ensures quality assurance but also helps new unexperienced employees to produce components efficiently. Main Takeaway The Kadi4Mat ecosystem offers the possibility to store and structure data and automise their documentation.This makes FAIR data handling effortless in everday research. KadiWeb Structured data management and exc | poster |
Archivieren am Data Center for the Humanities der Universität zu Köln Kontakt: info-dch@uni-koeln.de https://dch.phil-fak.uni-koeln.de CC-BY 4.0 Anke Debbeler (Camunda BPMN 2.0 Dia- gramm, Text), Felix Rau (Text), Elisabeth Mollenhauer (Lay- out) Stand: August 2024 (Version 1.0.0) https://doi.org/10.5281/zenodo.13375261 LAC DATA & METADATA CONVERSION PIPELINE Das Diagramm dokumentiert formal den Konvertierungsprozess, den Daten und Metadaten nach der Übergabe während der Ge- nerierung des Archival Information Package (AIP) durchlaufen, bevor sie ins LAC überführt und publiziert werden. Zur Datenübergabe gibt es mehrere Optionen: Diese hängen von der Datengröße und dem Zugang der Datengeber*innen zum Cloud-Service Sciebo ab, der vom DCH verwendet wird. Das LAC nutzt das Profi l Basic Language Archive Metadata (BLAM) des ISO 24622-Standards Component Metadata Infrastructure (CMDI). Die Datengeber*innen liefern die Metadaten in einem auf das LAC angepasste Excel Sheet, das im Rahmen der AIP- Generierung in dieses Profi l überführt wird. Die Architektur des LAC basiert auf dem Oxford Common File Layout (OCFL), für dessen Anforderungen die Ordnerstruktur der überreichten Daten angepasst werden muss: Eine für das LAC spezifi sche Besonderheit ist hierbei die Unterteilung eines Datensatzes (Collection) in mehrere Bundles. Ein Bundle ist in der Regel äquivalent zu einer Aufnahme(session), zu der jeweils eine Medien- und eine Annotationsdatei zugeordnet werden. Die Datengeber*innen haben die Möglichkeit, der Collection bzw. den Bundles zusätzliche Metadatendateien hinzuzufügen. Die Generierung des AIP ist Teil des LAC Depositing Workflow, dessen formale Dokumentation hier einsehbar ist: https://doi.org/10.5281/zenodo.13375243. Das Data Center for the Humanities (DCH) bietet über das Language Archive Cologne (LAC) die Sicherung und Publi- kation audiovisueller Daten an. Im Sinne der FAIR-Prinzipien (Findable, Accessible, Interoperable, Reusable) stellt das LAC einen offenen, webbasierten Zugang zu hochwertigen digitalen Sprachressourcen zur Verfügung. Als ein mit dem CoreTrustSeal (CTS) zertifi ziertes Reposito- rium innerhalb der europäischen Common Language Resources and Technology Infrastructure (CLARIN) arbeitet das LAC nach dokumentierten Arbeitsprozessen, die Qualität und Integrität von Daten und Metadaten sichern. | poster |
Case study Climate Change : How Earth System Science benefits from FAIRCORE4EOSC components Anna-Lena Flügel1, Heinrich Widmann1, Beate Krüss1, Hannes Thiemann1, Stephan Kindermann1 , Fanny Adloff1 EGU General Assembly 2024, Vienna, Austria The European Open Science Cloud (EOSC) is an ecosystem of federated research data and services, and an open science infrastructure. FAIRCORE4EOSC (FC4E) supports a FAIR EOSC by developing nine new core components improving cross-domain interoperability. Challenges ●EOSC services need to be cost-effective, scalable, reliable, trustworthy and sustainable long-term ●Required adaption on ENES side to offer customized and easy-to-use services ●Technical incompatibilities due to different technologies and standards Requirements of Case Study ‘Climate Change’ Five thematic case studies drive the development of the FAIRCORE4EOSC (FC4E) technical components. DKRZ1 specifies the user requirements for the case study ‘Climate Change’ and works with the FC4E developers on the integration of several components into ENES RI. RAiDs (Research Activity identifiers) are being assigned to the CMIP6 project, providing an aggregated view on related entities (data provenance, software, people involved, etc). PIDGraph assigns DOIs to different aggregation levels of CMIP6 data, connects DOIs and RAiDs, links data collection metadata and makes it findable within the RD Graph. The EOSC RDGraph (Research Discovery Graph) enables advanced and cross domain data discovery and access for the ENES community and researchers from other scientific areas. MSCR (Metadata Schema Crosswalk Registry) improves cross-domain reuse of ENES data by mapping climate variable vocabularies to other ontologies. DTR (Data Type Registry) defines and registers standardized simple and complex data types and thus enhances machine actionability. 1 German Climate Computing Center (DKRZ, https://www.dkrz.de) Integration of FAIRCORE4EOSC components into ENES-RI Services Benefits ●improved interoperability and traceability of research activities ●enhanced discovery, access and reuse of data collections (FAIR) ●high scientific relevance for Earth system Science data producers and reusers Summary This poster gives an overview of the integration of five FAIRCORE4EOSC components into ENES RI and the long-term benefits for Earth System Science researchers and beyond. The use of FAIRCORE4EOSC components RAiDs, DTR, MSCR, PIDGraph and RDGraph improve discoverability, reusability and traceability of ENES data. Adaption of FAIRCORE4EOSC components for FAIR data management for Earth System Science within the case study ‘Climate Change’ ENES-RI ENES-RI is the research infrastructure for European Network for Earth System modelling (ENES), a collaboration of partners in climate modelling, climate impact research, IT and data management. The ENES-RI aims to ●deliver services to access climate model data ●develop tools to boost the understanding of future climate variability and change ●provide climate projections for policy decisions on mitigation and adaptation strategies, e.g. by the Intergovernmental Panel on Climate Change (IPCC) Anna-Lena Flügel fluegel@dkrz.de Acknowledgement This work has been funded by the European Commission under the projects IS-ENES grant no. 824084 (H2020) and FAIRCORE4EOSC grant no. 101057264 (HE) References FC4E https://faircore4eosc.eu ENES https://is.enes.org EOSC https://eosc.eu | poster |
Display of Results Running Taverna Workflows within IPython Notebook Alan Williams, Aleksandra Pawlik, Carole Goble, University of Manchester, UK Future Work Collation of provenance • The provenance of the workflow runs will be linked with the history generated by IPython Notebook Creation of Research Objects • Combine the IPython Notebook, the workflows and the linked provenance within a “Research Object” - http://www.researchobject.org/ Creation of documentation • Use IPython or dexy to generate reports about workflow runs Running the Taverna Player directly on the Taverna Server • The Taverna Player currently has to be within a Taverna Portal, or similar workflow registry. • In the future, Taverna Player will be extended to run directly against a Taverna Server • Will allow running of “arbitrary” workflows and allow them to be exposed in IPython Notebook Improved interaction • Allow the data entered in an interaction to come from values within IPython Notebook Teaching • Use the combination of IPython Notebook and Taverna to provide training materials Taverna Player • Allows Taverna workflows to be run as part of a website like embedding a video from Youtube • Uses Taverna Portal for user authorization • Reads workflows from a Taverna Portal • Runs workflows on a Taverna Server • Has a REST API Links IPython and IPython Notebook www.ipython.org The Taverna Player code on GitHub at www.github.com/myGrid/taverna-player The Taverna Player Client package at www.pypi.python.org/pypi/tavernaPlayerClient and the code on GitHub at www.github.com/myGrid/DataHackLeiden Taverna’s homepage at www.taverna.org.uk Acknowledgments This work was enabled by the BioVeL project, that has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 283359, and also enabled by the Software Sustainability Institute supported by the UK Engineering and Physical Sciences Research Council (EPSRC) through grant EP/H043160/1 Much of the work on the Taverna Player Client was carried out during the “Data enrichment hackathon” organized by pro-IBiosphere. Thanks are due to Ross Mounce of the University of Bath, UK and to Youri Lammers of Naturalis, Netherlands for their work on the client during the hackathon. Thanks are also due to the developers of IPython Notebook for their help and advise during the hackathon. Architecture Use Case The example notebook shows the running of a series of workflows for Ecological Niche Modelling (ENM), using the Taverna Player Client and the pandas and random Python packages. A file of csv data representing occurrences of species is read. 100 rows are selected at random for use in the Ecological Niche Modelling. A model is created and projected for the present day and for 2050. The results of the ENM are re-organized and then used as inputs to two other workflows: one to produce statistics and one to calculate the differences (climatic effects) between the projections. Client Creation Taverna Player Client • Uses Taverna Player and its Server to run workflows within an IPython Notebook • Data passed from the Notebook to the executing Taverna Workflows • Workflow run’s requests for data answered within the Notebook using Taverna’s interaction service • Results retrieved from the run and fed back into the Notebook • Available from the PyPi registry • Tested with BioVeL workflows for data refinement and ecological niche modelling. Interaction with Run Organization of Data Taverna Server • Runs arbitrary Taverna 2 workflows • Secure, isolated, user-specific workflow execution • Manages data for separate runs • Publishes interactions and provenance Use Case Introduction IPython Notebook, originally developed by Fernando Perez of University of Berkeley (where the core development team is currently based) is a browser-based environment for interactive computing. Users can write, edit and re-run Python scripts. IPython Notebook has suppor | poster |
An MPC Framework for Online Motion Planning in Human-Robot Collaborative Tasks Motion planners in human-robot collaboration must: Be fast (online with sampling period of few ms) Be optimal Reactto the human state (and prediction) We propose a recedinghorizonframework thatruns online in less than1 ms and adapts the robot motion to the state of the operator. Main features: Stackof tasks(SoT) : Online trajectoryscalingto slow down the task whenthe operator isclose to the robot without modifying the path Redundancyisusedto keep the robot far from the human Robot constraintsare explicitly taken into account Marco Faroni Manuel Beschi Nicola Pedrocchi CNR-STIIMA marco.faroni@stiima.cnr.it Thanks to the trajectory scaling, the geometrical curve is preserved: when the human is closer than the safetythreshold, the trajectory is slowed down when the distance is below the stoppingthreshold, the trajectory reaches null velocities The plannerusesthe redundancy to keepthe robot farther from the operator whenthe human is in the robot workspace(blackline always above blue line) stopping threshold scaling activation threshold clearance activation threshold Experimental test case: Universal robot UR5 on a linear guide (7 degrees of freedom) Pick-and-place ripetitive cartesian task Limits on joint positions, velocities, and accelerations Human position is provided by 4 time-of-fly cameras The research leading to these results was partially funded by the European Union H2020-ICT-2017-1 – Pickplace: Flexible, safe and dependable robotic part handling in industrial environment (grant agreement: 780488). 1. CARTESIAN TASK 2. VELOCITY SCALING 3. CLEARANCE | poster |
Henning Lange-Asschenfeldt Response of assumed interfacial charge carrier turbulence in interconnected electrical conductors to thermal diffusion or gravitational force Section from circuit or particulate structure 1 2 Two-component design (e.g. Fe/Ni or Si/C, roughly schematic) 1 2 - A comparative view - Interfacial transition zone (ITZ) Original (unaffected) state (Dynamic polarisation site) Available heat consumption Minor support current Translocation of charge carrier turbulence Gravitational force particulate solid structure Summation effect in ? (regulated) (Attraction) Gravitoelectric effect 2 Proportionate intensification Heat supply Thermoelectric effect (Seebeck) 1 of charge carrier turbulence Poster contribution | poster |
Resistance breaking strains of tomato spotted wilt orthotospovirus: distribution and evaluation of their impact on tomato and pepper production Funding Non-competitive funding mechanism. Each funder only pays for the participation of their own national researchers. Total funding € 50 000 Picture 1 Picture 1 Picture 1 Goals The goal of the project is to investigate the tomato spotted wilt orthotospovirus’ genome differences between resistance breaking (RB) isolates from tomato and pepper and non-RB isolates of these hosts. This investigation seeks to clarify if previous reports of genome motifs responsible for RB phenotypes are universally present in RB isolates from geographically distant areas Research consortium DAF (AU), CREA (IT), NIB (SI) Contact information Project coordinator: Cherie Gambley Cherie.Gambley@daf.qld.gov.au Key outputs and results The expected project results are: • knowledge of the impact of resistance breaking isolates in Australia, Italy and Slovenia • a collection of geographically diverse, phenotypically and molecularly characterised, isolates of tomato spotted wilt orthotospovirus • knowledge of the virus genetics: clarification of the presence of the putative single amino acid changes at positions Y118 or N120 in the non- structural protein (NSm) gene in RB-tomato isolates or identification of alternative putative motifs responsible for the RB phenotype in tomato, pepper and weed hosts Objectives The project objectives are: • to collect and phenotype a range of tomato spotted wilt orthotospovirus isolates from pepper, tomato and other hosts including weed species from Australia, Italy and Slovenia • to generate full genome sequences of these isolates • to compare full genome sequences of RB isolates and non-RB isolates to identify differences that potentially confer the RB phenotype • to review diagnostic protocols for the detection of RB isolates on the basis of the newly derived genomic data 03/2021-02/2023 | poster |
Metadata: Conditions data Handling Detector Characterization Data (Metadata) in XENONnT Conditions Data Processed Data Metadata Storage As an example, in XENONnT we needed to track crucial detector conditions like liquid xenon purity, which we monitor in terms of the electron lifetime. The electron lifetime determines the likelihood of electron absorption by impurities, thereby affecting energy reconstruction of interactions. How we calculate this value has changed over time so we needed to keep track of these multiple methods via different versions. Red: 222Rn alpha, Blue: 83mKr, green: 37Ar. Including the condition by charge up Electric field model. Gray band is the measurement by purity monitor, with systematic uncertainty. RFrame is a metadata framework that offers indexing features, similar to Pandas dataframes, but can operate on multiple storage backends. The goal of RFrame is to provide the following properties: ● Support for multi-indexing using discrete or continuous values, allowing for complex data structures to be easily represented. ● Checking and enforcement of values and index data types to ensure data integrity and consistency. ● Arbitrary rules for reading and writing to the database, giving developers flexibility in how they interact with the data. ● Support multiple data access storages. ● Python functions can be used to insert, delete, and modify data, allowing for easy integration with existing codebases. Xedocs was built based on RFrame and it handles the XENONnT specific needs for metadata management. At its core, xedocs consists of a collection of schemas that define the rules that different kinds of metadata need to follow. Base corrections Time sampled Time interval Base resource reference Map corrections Example: Electron Lifetime By: Luis Sanchez, Rice University, USA Yossi Mosbacher, Weizmann institute of science, Israel Aaron Higuera, Rice University, USA Christopher Tunnell, Rice University, USA RFrame Xedocs JSON Mongo Tinydb Our processing pipeline uses global versions, which is a list of lineages specifying the version of all the conditions metadata used to process a set of data. The conditions metadata can be separated into 2 broad categories: ● ONLINE version: Updated periodically and allows for extrapolation of values. Values here can only be changed in the future in terms of the time index. ● OFFLINE version: Allows for interpolation when processing a data segment with values before and after the time the data was taken. Offline versions can become obsolete as they are replaced with new versions. Raw Data Processing Pipeline Experiment Links To code: ●https://github.com/jmosbacher/rframe ●https://github.com/XENONnT/xedocs Experiment Monitoring Tools Manual Inputs - Version indexing - Time indexing - Updating rules - Other conditions metadata dependent requirements xarray API ODM API Has its own versioning system Pandas df Lists Dicts - _Alias attribute is always unique - Schemas include a versioned index - Changing already set values is not allowed - Adds an interpolation index of type datetime - Enforces rules on inserting new data points - Adds an interval index of type datetime. - Enforces rules on updating intervals. - Requires existence of resource in a database prior to inserting a new document - Requires an ‘algorithm’ index of type string. These schemas can be used to define the different kinds of conditions metadata we need and are built inheriting for the previous one. API’s Data backends In memory datatypes Many experiments have their own system to store, organize and track conditions data, but in many cases it is not possible to copy the system of another experiment due to how specialized to their experiment this system will be. In XENONnT we developed an open source tool in python to facilitate conditions data management and storage, which we call rframe and xedocs. We needed tools to handle versioned and time-indexed conditions data, as well as to impose rules regarding how the va | poster |
Rapid “mix-n-match” evolution of a housekeeping protein in response to bacterial antagonism EmilyClare Baker ¹, Kristin Kohler¹, Matt Barber¹ ¹University of Oregon Institute of Ecology and Evolution Based on PAML⁵ analysis of CEACAM proteins from 19 hominid, Old World Monkey and New World Monkey primates. The CEACAM protein family⁴ A multifunctional cell adhesion family in vertebrates N domain (IgV-like) IgC2-like domains* TM Cytoplasmic domain protein-protein binding domain includes ITIMs and other signaling motifs* (*presence and composition variable) *Number varies from 0 to 6 between different proteins and isoforms CEACAM protein domain structure Several bound by bacteria • CEACAM1 • CEACAM5 (CEA) • CEACAM6 • CEACAM3 Functions include... • Cell adhesion • Intra- and Intercellular signaling • Immune function • Cell cycle modulation CEACAMs 1, 5 & 6 • strong markers of cancer progression and prognosis • expressed on epithelia (esp. gastric) and immune cells • housekeeping proteins involved in cellular signaling CEACAM3 • expressed on immune cells • likely a dedicated immune protein Region bound by bacterial adhesins CEACAMs bound by bacterial adhesins the most rapidly evolving in primates • niche construction • immune evasion Bacterial adhesin proteins can exploit cell surface proteins for...⁴ • movement through the host Potentially decreasing host fitness bacterial adhesin – host protein interactions Consequences of evolutionary conflict between pathogens and host ‘housekeeping genes’ • Pathogen antagonism is predicted to lead to an ‘evolutionary arms race’ – characterized by rapid evolution host and bacterial proteins. Model of bacterial adhesin host protein evolutionary arms race 1 Bacterial adhesin is unable to bind to the host epithelial protein 2 Pressure to manipulate host drives evolution of bacterial adhesin to bind host protein 3 Pressure to prevent exploitation favors evolution of host protein away from adhesin binding 4 Pressure to evolve shifts back to the bacterial adhesin If and how housekeeping genes can evolve against pathogen exploitation is unclear. How host ‘housekeeping’ proteins can evolve to evade pathogen exploitation and maintain essential functions is an open question. Sites under selection are concentrated in the N-domains* domain targeted by bacterial adhesins * based on NS-sites analysis in PAML HopQ CEACAM1 N-domain Some sites under selection localize to interface with H. pylori HopQ Highlighted sites indicated as under selection by phylogenetic analysis programs PAML, FEL⁶ and MEME⁷ Bonobo CEACAM1 N-domain is unable to bind HopQ and has unusually divergend protein sequence 1. Correa P, Piazuelo MB. Evolutionary history of the Helicobacter pylori genome: Implications for gastric carcinogenesis. Gut Liver. 2012;6: 21–28. doi:10.5009/gnl.2012.6.1.21 2. Ishaq S, Nunn L. Helicobacter pylori and gastric cancer: A state of the art review. Gastroenterol Hepatol from Bed to Bench. 2015;8: S6–S14. 3. Javaheri A, Kruse T, Moonens K, Mejías-luque R, Debraekeleer A, Asche CI, et al. Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs. Nat Microbiol. 2016;17: 16189. doi:10.1038/nmicrobiol.2016.189 4. Gray-Owen SD, Blumberg RS. CEACAM1: Contact-dependent control of immunity. Nat Rev Immunol. 2006;6: 433–446. doi:10.1038/nri1864 5. Yang Z. 2007. PAML 4: phylogenetic analysis by maximum likelihood. Mol Biol Evol. 24:1586–1591. 6. Kosakovsky Pond SL, Frost SD. Not so different after all: a comparison of methods for detecting amino acid sites under selection. Molecular biology and evolution. 2005 May 1;22(5):1208-22. 7. Murrell B, Wertheim JO, Moola S, Weighill T, Scheffler K, Pond SL. Detecting individual sites subject to episodic diversifying selection. PLoS genetics. 2012 Jul;8(7). 8. Guindon S, Dufayard JF, Lefort V, Anisimova M, Hordijk W, Gascuel O. New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst | poster |
Demobase: DEsign and MOdelling for improved BAttery Safety and Efficiency Headline Converging the efforts of the GV7 call, which is addressing efficiency and cost reduction on the integration related aspects of motors, power electronics and transmission, DEMOBASE aims at the generation of the necessary tools and technology solutions that will drastically reduce price differences between conventional and electric vehicles while assuring much lower operational cost, higher efficiency, higher availability, increased driving range as well as improved comfort and attractiveness. In DEMOBASE, cost reduction activities, higher car performances and availability, mainly on the key battery system component, will be achieved through incremental and breakthrough research activities and demonstrated in a dedicated demonstration vehicle. The EV demonstration focuses on the sector of electro-mobility with the highest growth, i.e. four wheels urban vehicles. These activities will be supported by highly advanced multi- level and multi-domain simulation. A key aspect will be gateway development to ensure the seamless process effectiveness for a variety of software environments. Specific objectives: • Cost reduction of batteries: will be tackled by a seamless development chain with drastically reduced development time and costs, enabling as an additional benefit also faster integration of new cells. An innovative seamless development process from cell and from active material to vehicle using multi-level modelling integrating battery management, ageing, safety, recycling and availability will cut down development time by at least factor 2. • Cost reduction of chassis: The methodology developed with the FP7 PLUS MOBY project ended December 2016 will be further advanced in DEMOBASE making it (ubiquitous) parametric and applicable to most vehicle categories. DEMOBASE will develop and demonstrate breakthrough methodology that allows the design and development of novel safe chassis in less than one tenths the usual time and at a small fraction of the usual cost. • Battery safety: improved without additional expense, battery risks will be addressed by a fail aware concept to ease vehicle fleet management. DEMOBASE develops new safety approach based on tests at cell level and innovative battery model to manage fire risk, gas flammability, gas toxicity at vehicle level. • Battery availability: The new battery system functionalities make it immune to thermal runaway events. Residual fire or thermal runaway risk will be managed inside the vehicle without stop of service, which is the today’s standard fail safe management, with fail operational concept supported by specific battery architecture and innovative safety components. • Accelerated battery ageing modelling: Innovative characterization technics are used to develop battery ageing models within 4 months. • Battery recycling as part of the process: To close the life cycle, tools and recommendations for safe and efficient recycling will be elaborated. DEMOBASE develops End to End safety activities from active material to recycling where recycling is part of the overall development process. Moreover the novel approach for chassis design leads to radical reduction of the large quantity of adhesives currently used in the automotive world, easies disassembling of the elements composing the full vehicle; it is another mind shift in auto world. This will reduce the recycling costs by up to 25%. • Radical reduction of the necessary investments: Process capability for a variety of different vehicle architectures derived from a single chassis will be demonstrated. • Scalability of design for both vehicle and battery system: a parametric methodology to design and developed batteries and a new chassis will be demonstrated for different vehicle classes. • The efficiency of e-drivetrains under real conditions will be increased by 20%. For this purpose, the project will develop and demonstrate wheel-tire design wit | poster |
t Funded by the Horizon 2020 Framework Programme of the European Union THIS PROJECT HAS RECEIVED FUNDING FROM THE EUROPEAN UNION’S HORIZON 2020 RESEARCH AND INNOVATION PROGRAMME UNDER GRANT AGREEMENT NO. 818309 (LEX4BIO). THIS OUTPUT REFLECTS ONLY THE AUTHOR’S VIEW AND THE EUROPEAN UNION CANNOT BE HELD RESPONSIBLE FOR ANY USE THAT MAY BE MADE OF THE INFORMATION CONTAINED THEREIN. Plant nutrient and harmfull heavy metal concentrations in agricultural soils of EU27 and UK Kari Ylivainio1, H. Eigner3, S. Geyer3, A. Skyttä1, L. Jauhiainen1, A. Delgado4, A. Jones5, J. Santner2 1Natural Resources Institute Finland (Luke), Jokioinen, Finland, 2Department of Crop Sciences, Institute of Agronomy, University of Natural Resources and Life Sciences, Vienna, Austria, 3Agrana Research & Innovation Center GmbH, Tulln, Austria, 4University of Sevilla, Spain, 5Joint Research Center (JRC), Ispra, Italy Introduction Farm-to-Fork strategy aims to reduce nutrient losses by 50%, which is expected to decrease the requirement for fertilisers by 20% by the year 2030. To reach these ambitious targets, it is of utmost importance to know the nutrient status of agricultural soils for optimising fertilisation according to crop requirement. Furthermore, substitution of mineral fertilisers with bio-based fertilisers (BBF) reduces the need for finite phosphorus (P) resources and production of energy intensive mineral nitrogen (N) fertilisers. However, BBFs may contain other elements than only desired plant nutrients. Therefore, both nutrient and harmful heavy metal concentrations in BBFs and agricultural soils needs to be known in order to select technologies for producing safe BBFs for ensuring food and feed safety. Material and methods In this study, a sub-set of soil samples from the LUCAS soil sample archive, collected in 2015 (https://publications.jrc.ec.europa.eu/repository/handle/JRC 107926), were analysed for their soluble elemental composition. The selection of soil samples from the EU27+UK was based on proportional allocation with the following criteria: soil pH, carbonate content, texture, organic carbon content, and Olsen-P values. A total of 1,661 soil samples from cropland (out of 9,246 samples) were selected and soluble concentrations of P, K, Zn, Cu, Pb and Ni were analysed with the electro-ultrafiltration (EUF) method . Results Soluble P concentration varies greatly across Europe with highest concentrations in western Europe (Fig. 1) Soil K concentrations are evenly distributed in Europe Highest concentration of Zn follows the same pattern as P High Cu concentrations were found from the Mediterranean region. Highest average Pb concentrations were found from the western Europe, whereas Ni concentration were more elevated in the eastern Europe. Conclusions Requirement for P fertilization varies across Europe and high soil P and Zn concentrations are found in regions with high animal density Concentration of soil Cu high in regions with vineyards and orchards, probably originating from pesticides Soluble Pb concentration follows the same trend with Zn, whereas high Ni concentrations may be due to indigenous soil properties Due to the variation in soluble elemental composition of agricultural soils in Europe, properties of BBFs needs to match to local soil conditions in order to secure food and feed safety and minimize environmental losses Figure 1. Soluble P, K, Zn, Cu, Pb and Ni concentrations in European croplands (EU27 + UK) according to the EUF-method | poster |
Filter Testing Services for Pharmaceutical and Medical Device Manufacturers STEMart, a US-based provider of comprehensive services for all phases of medical device development, has announced the launch of its new Filter Testing Services for pharmaceutical and medical device manufacturers. These services are designed to help manufacturers ensure the safety and efficacy of their products by verifying the performance of filters used in the manufacturing process. Filtration sterilization is an important unit operation in the aseptic manufacturing process. It requires proper process validation to verify the performance of the filters used for sterilization filtration. Filter testing is used to evaluate a filter's ability to separate microorganisms of various sizes and helps manufacturers determine membrane pore size. This test is also an excellent batch release test. Test data can also be used as an effective marketing tool. STEMart provides comprehensive facility and process validation for medical devices. With extensive expertise in Filter Testing, STEMart can provide a full service experience to assist manufacturers in meeting regulatory goals and minimizing compliance risks. The comprehensive Filter Testing services are guided by "Sterile Drug Products Produced by Aseptic Processing - Current Good Manufacturing Practice", the FDA guidance document for industry, which outlines the general considerations the FDA believes should be taken into account when performing filter testing for a medical device. STEMart offers a wide range of Filter Testing services. For example, Retention Capacity and Filtration Efficiency Test demonstrates the filter's ability to remove all bacteria from a liquid bacterial suspension under specified conditions according to ASTM 838-05. Validation of the filtration process takes into account all factors that may affect the performance of the filter, such as pH, viscosity and compatibility of the material being filtered with the filter, flow rate, pressure, temperature, and hydraulic shock. Filter Extractables Test identifies and quantifies compounds that have the potential to become leachables. Suitability Test verifies that the filter meets all requirements under product and process conditions, including, but not limited to, resistance to high temperatures, resistance to fatigue under pressure and flow changes, and resistance to high pressure changes. Based on ISO 10992 and ISO 18562 standards, FDA guidelines, ASTM (American Society for Testing and Materials) standards and other international guidelines, STEMart's experts have many years of experience in a wide range of testing services for Class I, II and III medical devices and can help clients ensure that every aspect of the medical device is properly tested. If you have additional questions about Filter Testing or would like to find out more | poster |
Estimating Mutation Parameters and Population History Simultaneously from Temporally-Spaced Genome Data Arman Bilge, Tanja Stadler, Matthew Kearse, and Alexei J. Drummond email: abil933@aucklanduni.ac.nz Estimating Mutation Parameters and Population History Simultaneously from Temporally-Spaced Genome Data Arman Bilge, Tanja Stadler, Matthew Kearse, and Alexei J. Drummond email: abil933@aucklanduni.ac.nz Motivation and Primary Challenges ▷Very feasible to sequence entire genomes ▷More recently, even possible to recover ancient genomes ▷Temporally-spaced genome data ▷Opportunity to do inference previously only possible for fast-evolving organisms (e.g., viruses) ▷mutation rate ▷population size through time But. . . ▷Difficult to phase diploid genomes ▷Recombination ▷Low coverage and sequencing error, especially for ancient genomes ▷Cannot use existing Bayesian phylogenetic methods Sequencing Depth and Error ▷Assume that all individuals have about same number of SNPs ▷Average sequencing depth of sample is correlated with observed SNPs ▷Our dataset approaches complete SNP recovery at 22x coverage ▷Ancient genomes are sequenced at lower depth and thus missing many SNPs ▷Leads to systematic bias in estimates 4 8 12 16 20 24 28 4 4.5 5 5.5 6 6.5 7 ·106 Average Depth Recovered SNPs Overview of Methodology ▷Want to estimate mutation and population parameters θ from pileup data ▷pileup data is unsummarized, aligned reads for each sampled individual ▷To compute posterior need to marginalize over individual’s genotypes ▷Computationally intractable so use importance sampling ▷The importance distribution assumes independence of individual’s genotypes P (θ | D) = X G P (θ | G) P (G | D) = lim n→∞ n X i=1 P θ | G (i) P G (i) | D ˆP G (i) | D , G (i) ∼ˆP (· | D) ▷Finally, use standard MCMC to sample parameters for a given genotype P (θ | G) ∝P (G | θ) P (θ) Sampling an Individual’s Genotype ▷Want the genotype g1, g2 ∈{A, C, G, T} of individual at a position in its genome ▷Data is the observed base calls at this position with their Phred quality scores D = (bq : b ∈{A, C, G, T} , q ∈N) ▷Number of base calls |D| is the sequencing depth at this position ▷Sample genotype from the posterior distribution P (g1, g2 | D) = P (D | g1, g2) P (g1) P (g2) P (D) ▷To compute P (D | g1, g2) assume base calls are multinomially distributed with probabilities P (bq | g1, g2) = 1 2P (bq | g1) + 1 2P (bq | g2) ▷Using the definition of a Phred quality score (assuming equal error rates for all bases) P (gi | bq) = ( 1 −10 −q 10 ifb = gi 1 310 −q 10 ifb ̸= gi we have P (bq | gi) = P (gi | bq) P (bq) P (gi) ▷Use empirical estimates for P (gi) and P (bq) Genotype Probability ▷Assumes that sites are unlinked; i.e., phylogenetically independent ▷Models recombination with no dependence on correct phasing ▷Assumes a site is biallelic; i.e., has only two possible nucleotide states ▷Often true in practice ▷Can be handled rigorously with ascertainment bias correction ▷Want the probability of all the individuals’ genotypes by marginalizing over all phylogenies P (G | θ) = Z T P (G | T, θ) P (T | θ) dT ▷Integral is computed numerically using similar technique to SNAPP [2] ▷Divide time into intervals using sampling times and population change times ▷Each interval i can be described by a linear system of differential equations Qi ▷Solve each system by taking the matrix exponential exp Qi [1] ▷Can be done efficiently by caching and reusing matrix exponentials Simulation Study ▷8 diploid taxa, including 4 ancient individuals up to 50k years old ▷Mutation rate µ = 10−9 s/s/yr ▷HKY model with κ = 5 ▷Constant size population with Ne = 3 × 106 ▷Simulated 50 datasets of 104 total sites ▷Attempted to infer parameters ▷True values always within 95% HPD ▷Mean ˆµ within ±1.8 × 10−10 of true µ G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 0e+00 1e−09 2e−09 3e−09 0 10 20 30 40 50 replicates Mean Summary ▷Fully Bayesian inference of mut | poster |
An assessment of potential Plato Observing strategies to maximize science return from the Kepler Field. J.F. Rowe, D. Jontof-Hutter, J. Lissauer Bishop’s University, University of the Pacific, NASA-Ames The Plato Mission has the unique capacity to provide long-base observations of thousands of stars and their transiting planets. The current mission plan includes a 2-year stare than includes the Kepler Field. Plato observations have the potential to improve science return from the Kepler field. Including, the reliability of Kepler planet candidates in the low S/N regime, detection of long-period planets and an overall improvement of exoplanet occurrence rates and transit timing variations and long-term stellar variability and stellar cycles. The low S/N transit regime includes potential Earth-sized habitable zone planets around Sun-like stars, which is of high intellectual interest. Abstract Kepler Planets Plato detection SNR in the Kepler Field The baseline Plato mission includes a 24 month continuous stare that includes the Kepler Field. Due to orbital constraints, the Kepler is located towards the periphery of the Plato FOV and will be covered by 6 - 12 cameras. This is roughly equivalent to 1/8 to 1/4 of the Kepler light gathering ability. Figure 2, shows an estimate of the expected SNR of a planet transit in the Kepler Field observed by Plato. Of note, is the very low SNR recovery of long-period planets with a radius less that ~ 4 R⊕. Figure 3 shows the hypothetical scenario of observing the Kepler Field, but centred in the Plato FOV. Note, this configuration is not possible. However, by centring the FOV, there is an overall increase in transit SNR recovery which greatly benefits planets smaller than 4 R⊕. Figure 4 shows our proposed observing plan which would centre the Kepler Field, and to break the observing campaign into four 6-month campaigns. This gives the benefit of more Plato Glass on the Kepler field, but extends the observing baseline to 4- years, which allows for recovery of approximately half of Kepler’s long-period Earth-sized planets. Notice the significant increase in SNR for planets with periods greater than 300 days and radii less than 4 R⊕. Figure 1 shows the average SNR per transit vs orbital period and radius. The average SNR generally increases with radius. Trends associated with period are a result of the Kepler mission requiring a total SNR ≳ 7.1 for candidate selection, thus few transits requires a large average SNR per transit for detection threshold. Figure 1 Figure 3 Figure 4 Also: see Talk by J. Lissauer and Poster by D. Jontof-Hutter Figure 2 | poster |
Meta The case: Nanocatalytic powders as coating in automotive industry Cu/Pd/Rh doped on Ce/Zr mixed oxide Nanosized copper-based catalyst for automotive: physicochemical characterization. A. Soto Beobide1, A. M. Moschovi2, G. N. Mathioudakis1, M. Kourtelesis2, Z. G Lada1, K. S. Andrikopoulos1,3, L. Syggelou1, V. Dracopoulos1, I. Yakoumis2, G.A. Voyiatzis1 1 Foundation for Research and Technology / Institute of Chemical Engineering Sciences FORTH/ICE-HT, Patras, Greece 2Monolithos Catalysts & Recycling Limited, Athens, Greece 3Department of Physics, University of Patras, Patras, Greece * E-mail address of presenting author: asoto@iceht.forth.gr I) Outline In the automotive industry, catalytic devices accumulate concentrated loading of platinum group metals (PGMs, platinum, palladium, rhodium) as the active catalytic phase. The aim of MONOLITHOS Catalysts Ltd is the partial substitution of an amount of PGMs (mainly platinum) with abundant non-PGMs (transition metals). Several efforts have been made to use transition metals as substitutes and among them copper seems to be one of the best. PROM100 “fresh”: catalyst that has not been used at all PROM100 “aged”: artificially aging by submitting to hydrothermal (10% water) heating at 1050 oC for 4h. EU Directives for simulating more than 60,000Km of mileage of a car. Rama II) www.iceht.forth.gr Nanotechnology is conceived as a Key Enabling Technology, becoming an increasingly research area providing functional materials to many industrial sectors, such as automotive, health, packaging, textiles, construction, etc. The main objective of DIAGONAL project is to increase the understanding on Multi-Component NanoMaterials (MCNM) and High Aspect Ratio Nanoparticles (HARNS) behavior along their life cycle from NM design and production to its application into Nano-Enabled products (NEP). DIAGONAL aims to bring new methodologies to guarantee long-term nanosafety and contribute to fill current gaps in: Risk Assessment, Risk Management and Risk Governance. DIAGONAL will bring Safe-by-Design knowledge and tools to a development stage which can be implemented in the MCNM and HARNs related industries, relying on experimental (in vitro) and modelling (in silico) research to understand and ultimately predict the interactions among the NM components, their transformation products, and between the NMs and the environment, promoting a better understanding of potential adverse effects on human health, and biota. Metallic oxide NPs (Cu, Pd, Rh) over ceramic substrates of CeO2/ZrO2 (automotive catalytic converters for the transformation of toxic gases Physico-chemical characterization of PROM100 catalyst and its transformation along life cycle C) Raman Characterization E) X-ray diffraction, XRD Definition of Nanomaterial According to Commission’s recommendation [1] Prometheus catalyst (PROM100) Material with 50% or more of the particles in the number size distribution, present one or more external dimensions in the size range 1 nm-100 nm A material should be also considered nano when the specific surface area by volume of the material is >60 m2/cm3 D) X-ray photoelectron spectroscopy, XPS A) Gas porosimetry Surface area Specific surface area by volume PROM100 fresh: 81m2/g 528 m2/cm3 (*) PROM100 aged: 1 m2/g 6.5 m2/cm3 *Density (CeZrO4)= 6.52 g/cm3 B) Scanning electron microscopy, SEM PROM100 fresh PROM100 aged 200 300 400 500 600 700 800 Relative Intensity Raman Shift, cm -1 470 615 0=514 nm 200 300 400 500 600 700 800 Relative Intensity Raman Shift, cm-1 472.5 PROM100 fresh CeO2cubic fluorite: intensity peak at 465 cm-1 Ce1-xZrxO2mixed oxides: increasing x value -> shift to 470 cm-1 Broad and weak peak at ~620 cm-1: presence of oxygen vacancy in the fluorite phase which causes defects sites in Ce-Zr oxides for the activity of the catalyst [2] 200 300 400 500 600 700 800 638 616 567 537 383 348 333 306 258 221 190 Raman Shift, cm-1 178 Increase intensity peak Ce1-xZrxO2 at 472 cm-1 New peaks: ZrO2 | poster |
Open-Access-Büro Berlin Der Berliner Senat hat im Rahmen der Open- Access-Strategie ein Koordinationsbüro eingerichtet. Das Open-Access-Büro Berlin ist am Center für Digitale Systeme der Freien Universität Berlin an- gesiedelt und hat am 1. September 2016 die Ar- beit aufgenommen. Das Open-Access-Büro Berlin hat die Aufgaben, die Berliner Wissenschafts- und Kultureinrich- tungen über die Kernziele der Berliner Open- Access-Strategie aufzuklären, sie bei deren Um- setzung zu unterstützen und die verschiedenen Akteure zu vernetzen. Kontakt Dr. Andreas Hübner E-Mail: andreas.huebner@open-access-berlin.de Dr. Katja Mruck E-Mail: katja.mruck@open-access-berlin.de Tel.: + 49 (0)30 838-50244 Adresse für Besucher/innen: Freie Universität Berlin Ehrenbergstraße 26-28 14195 Berlin Postanschrift: c/o Freie Universität Berlin Center für Digitale Systeme (CeDiS) Ihnestr. 24 14195 Berlin www.open-access-berlin.de kontakt@open-access-berlin.de Andreas Hübner und Katja Mruck, Open-Access-Büro Berlin Das Land Berlin hat Ende 2015 eine Open-Access- Strategie verabschiedet, um den offenen Zugang und eine umfassende Nutzbarkeit im Sinne von Open Access in den Bereichen wissenschaftliche Publikationen, Forschungsdaten und Kulturelles Erbe zu fördern. Zielsetzungen Wissenschaftliche Publikationen Mit dem Jahr 2020 soll der Anteil an wissenschaft- lichen Open-Access-Publikationen (Grün und Gold) für Zeitschriften-Artikel aus allen wissenschaftli- chen Einrichtungen in der Zuständigkeit des Lan- des Berlin möglichst bei 60% liegen. Monografien und Sammelbände sollten ebenfalls Open Access verfügbar sein. Forschungsdaten Das Land Berlin setzt sich für den offenen Zu- gang zu und die Ermöglichung einer umfassenden Nachnutzung von Forschungsdaten ein und beab- sichtigt, konkrete Beiträge im Rahmen einer nati- onal und international abgestimmten Strategie zu leisten. Kulturelles Erbe Die bereits begonnene Digitalisierung des kultu- rellen Erbes des Landes Berlin wird fortgesetzt und erweitert. Das Land Berlin setzt sich für den offenen Zugang zu und die umfassende Nutzbar- keit von Kulturdaten ein. Der Aufbau von Kreativ- partnerschaften zwischen Akteuren aus Kultur, Kunst, Wissenschaft, Bildung, Forschung und Wirt- schaft wird unterstützt. Open-Access-Strategie für Berlin Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz. Siehe http://creativecommons.org/licenses/by/4.0/ Text: Andreas Hübner und Katja Mruck, verwendetes Bildwerk: Matten Vogel | poster |
Sea slugs from the Gulf of Mexico | poster |
Direct imaging of magma oceans in nearby young stellar associations Irene Bonati a,b, Tim Lichtenberg *,b, Dan J. Bower c, Sascha P. Quanz d, Miles L. Timpe e a Earth-Life Science Institute, Tokyo Institute of Technology, Japan b Institute of Geophysics, ETH Zürich, Switzerland c Center for Space and Habitability, University of Bern, Switzerland d Institute for Particle Physics and Astrophysics, ETH Zürich, Switzerland e Institute for Computational Science, University of Zürich, Switzerland * Presenter, now at: University of Oxford, United Kingdom irene.bonati@elsi.jp Ø Terrestrial planets are thought to undergo multiple magma ocean (MO) stages as a result of heat released during accretion (giant impacts), decay of short- lived radioisotopes and core formation. Ø Processes taking place during MO solidification set initial conditions for the planetary chemical structure, atmospheric composition, tectonic behavior, and habitability. Ø Next-generation direct imaging techniques could lead to the detection of such bodies, thus providing observational constraints for theoretical models and insights into the origin and diversification of planets in our Solar System and beyond. Ø We present a quantitative assessment of the observability of MO planets in nearby young stellar associations (SA) via future direct imaging facilities. II. 1D MO interior model2 I. N-body simulations1 à Occurrence rate of giant impacts (GI) during planet formation around A, G and M- stars à Surface temperature evolution after GIs à MO cooling through atmosphe- res of different emissivities (0 ≤ε ≤1) + steam atmosphere III. Telescope parameters: IWA + sensitivity • ELT ground telescope3 • Darwin-like space telescope4 à Explore optimal target selec- tion strategy à Constrain potential detectabi- lity of MO bodies IV. Probability of detecting at least one magma ocean planet in nearby stellar association5 References I. Timing and energy of giant impacts Ø Q > Qcrit à giant impact (GI) Ø Most GIs occur within the first 20 Myr of planet formation. Ø Post-impact bodies have radii 0.4 RE ≤R ≤1.1 RE. Ø Large planetary radius + low atmospheric emissivity à long MO lifetime Ø Evolution of steam atmosphere results in longer sustained MO Ø MO planets at angular separations θ ≥IWA à detectable II. Magma ocean (MO) cooling timescales III a. Detectability assessment: Inner Working Angle (IWA) III b. Detectability assessment: sensitivity IV. Probability of detecting MO planets IWA = 2λ D θ = tan−1 a d " #$ % &' [1] Grimm & Stadel, ApJ, 796, 23 (2014) [2] Bower et al., Phys. Earth Planet. Inter., 274,49-62 (2018) [3] Brandl et al., SPIE (2016) [4] Kammerer & Quanz, A&A, 204 (2018) [5] Mamajek, Proc. IAU Symp. (2015) + ref. therein Methodology Results References Conclusions Motivation Ø Target selection favoring young and close stellar associations containing a large amount of stars significantly increases the likelihood of detecting a MO event. Ø β Pictoris is the association best suited for potential future observations of collision-induced magma oceans, both with Darwin and ELT configurations. Ø Planetary flux evolution during lifetime of a MO Ø MO bodies having fluxes higher than telescope sensitivity thresholds à detectable Ø Observing mode: 30 h integration time for each star in a given stellar association θ = IWA Not detectable Detectable (inner working angle) 103 104 105 106 Time after GI (years) ! " ! " No. stars Association d (pc) Age (Myr) A G M β Pictoris 15 23 4 18 21 AB Doradus 20.1 150 0 23 8 β Tucanae 43 45 4 0 1 Tucana Horologium 48 45 2 27 5 Columba 50 42 2 37 1 TW Hydrae 53 10 2 0 33 Carina 65 45 0 22 0 32 Orionis 92 22 2 7 2 ⌘Chamaeleontis 94 11 1 0 11 χ1 For 99 50 2 0 0 PMO(λcen, d, ⌧⇤, ✏) = 1 − i=n⇤ Y i=1 1 −¯nGI,i · ∆tobs ¯R,i ∆tbin,i ! GI | poster |
The province of Alberta is home to one of the World’s largest sedimentary basins. And the Oil and Gas industry has been Alberta’s main source of economic prosperity for more than half a century. The oil sand deposits are the province’s biggest oil producers, and due to the nature of bitumen and heavy oil, enhanced oil recovery techniques such as Steam- Assisted Gravity Drainage or SAGD are required. Oil and Gas and in particular the oil sands operations, have raised lots of negative Environmental concerns. And In addition, in recent years the government and companies have faced immense liabilities by the nonproducing wells. Alberta has one of the most polluting Grids across Canada and this is mainly because of Fossil Fuels. All these issues raise the demand for more alternative reliable sources of clean energy with little environmental impacts. Given the huge Sedimentary Basin and existing infrastructure geothermal energy has a good potential to be investigated and developed in Alberta. Geothermal Energy is the heat derived from the earth’s subsurface, can be Harnessed for Clean Electricity generation or space heating applications. The main advantages of geothermal energy is being weather independent, and its very high capacity factor. By providing sustainable clean energy solutions using Geothermal potential, Renewable Energy can penetrate the Alberta Grid to lower the GHG emissions, and since infrastructure such as drilled wells already do exists, a big portion of money needed for the initial investment can be eliminated. This project provides solution for decommissioned wells which are hazardous risk to human health and the environment and huge financial liabilities for government and companies. Converting just 10 percent of Alberta’s thousands suspended wells to geothermal can create business and work for hundreds of services and defer the high cost of well abandonment for companies Plus additional potential revenue from carbon tax credit by Reducing GHG emissions. Methods Conclusions Geologic Thermal Heat Storage and Recovery Alberta Sedimentary basin Sarvenaz Moazami - M.Sc. Student in Sustainable Energy Development, University of Calgary Introduction Results GeoThermal Heat storage • 4000 Solar troughs • Area of 200,000 m2 • Steam injected to Geothermal Storage • 3650 m3/day steam for storage • 12 pairs would be sufficient, 1 Depleted PAD • More than 4100 tCo2 reduced • 93% less than base case if Natural Gas used • $111k in Carbon Tax Credit • Initial investment $6.5 mil • NPV: $1.3 mil • LCOE 12 c/kWh References Wendt, e. a. (2019). Geologic Thermal Energy Storage of Solar Heat to Provide a Source of Dispatchable Renewable Power and Seasonal Energy Storage Capacity. GRC Transactions, 73-91. Ghoreishi-Madiseh, S., Templeton, J., Hassani, F., Al-Khawja, M., & Aflaki, E. (2014). Geothermal Energy Extraction From Decommissioned Petroleum Wells. Asian Rock Mechanism, 2644-2653. Bloomquist, D. R. (2012). Geothermal Space Heating. Washington State University Energy Program . Holman, J. P. (2009). Heat Transfer. In J. P. Holman, Heat Transfer (p. 752). McGraw-Hill Education. Urieli, I. (2020). Refrigerant and Heat Pumps. Retrieved from https://www.ohio.edu/mechanical/thermo/intro/chapt.1_6/chapter4c.html Reid, J. (2017). Geothermal Heat in Calgary: An Oil and Gas Retrofit. Calgary: University of Calgary. GeoThermal Heat storage 100% Renewable Microgrid, for 1000 Households in Firebag near Fort McMurray Solar Troughs for heat collection and Depleted SAGD pads for steam storage acting as synthetic Geothermal reservoir In Firebag, this means a Micro Grid of 1 MW Capacity, 7 GWh Electricity generation GeoThermal Space Heating For Geothermal Space heating facility design in Turner Valley, a model was designed for nearby residential buildings Temperature to stay around 25degC even during the coldest month of the year, for a 1000 households a Thermal Power Capacity of 5MW is needed. 18 GWh thermal energy Turner Valley field is produc | poster |
Application PHOTO–SENS Project EU-funded project of the program Horizon 2020 New generic tool with integrated optical sensing circuits for ultra-sensitive detection Wafer scale fabrication for cost-effective disposable bio-sensor Microfluidics cartridge enabling sample treatment & transfer of various water–based samples Functional and easy-to-use read-out device for use with disposable bio-sensing cartridge Identification of aquaculture-specific pathogens and respective biomarkers & serving as testing hub for fish farms Disposable cartridge: Microfluidic system Integrated buffers Integrated sensor chip Device Design: Cartridge handling Sample application Cartridge processing Final Product (Future): Industrial design User guidance Full automation Six sensor channels Two channels for process control Sensor chip: Miniature optical system Interference based on laser with modulated wavelength Assay development: Pathogen detection Early sturgeon sex detection Based on double stranded DNA Device Concepts: Liquid control Temperature control Sensor read-out Chip Development Device Development Optimization Surface coating: Anti-fouling Biofunctionalization for DNA detection This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 965643. See www.photo-sens.eu for more information. | poster |
Visualising the Student Journey Designed as an aid to examiners at Higher Education institutions, the Student Journey tool shows individual student’s progress throughout their programme. Three co-ordinated views [1] allows an overview, with detail of individual modules on demand. The tool also builds-in institutional regulations to make recommendations for the student’s outcome. Repeat Year / Semester 3 2:2 2:1 1 Start Semester 1 Semester 2 Semester 3 Semester 4 Semester 5 Semester 6 Final 3 2:2 2:1 1 SC2 3rd Year (Award) Year Group (2017/18) Computer Science Programme Student A Student 0 10 20 30 40 50 60 70 80 90 100 110 120 >= 40% < 30% Supp. Work Pass Number of Credits Step 1: Select a Student to see the overview. The Regulations view shows, in one bar plot, the possibility of a student progressing or receiving their award. Under most regulations if the red column is present, the student is unable to progress. Otherwise the must meet or exceed the Pass or Supplementary Work levels. Step 2: Click on the timeline to focus on an academic year. Figure 1: Timeline View Figure 3: Regulations View Cameron Gray Dave Perkins m Special Circumstances are highlighted by severity and shown in the appropriate semester. IED-3064 0% ICP-3036 7% ICP-3099 8% Figure 2: Module Detail View Semester 5 Semester 6 UXS-3071 65% @ Student achievement is shown as a coloured gauge. Red represents a failing result. . The Module Header block is proportional to the credit weighting. @ For each student, the tool produces a recommended action based on applicable regulations. 2 Orange coloured gauge lines represent a condonable result under institutional regulations. @ Green coloured gauges represent a passing result. The Module Detail view is a modified Sankey Diagram [2] to show both structure and achievement for the student. The inclusion of coloured gauges provides Pre-Cognitive Processing [3] by viewers. [1] Roberts, J.C. “State of the art: Coordinated & multiple views in exploratory visualization”. In: Coordinated and Multiple Views in Exploratory Visualization, 2007. CMV’07. Fifth International Conference on, pp. 61–71. IEEE. [2] P. Riehmann, M. Hanfler and B. Froehlich, "Interactive Sankey diagrams", IEEE Symposium on Information Visualization, 2005. IEEE. This tool was trialled during the 2017/’18 Final Award Board of Examiners’ meeting within Bangor’s School of Computer Science. It met with general approval and scored 79.65/100 using the Software Usability Scale. ICP-3042 80% [3] Ware, C., 2012. Information visualization: perception for design. Elsevier. School of Computer Science & Electronic Engineering UXS-3041 33% | poster |
VINEYARD INNOVATIVE TOOLS BASED ON THE INTEGRATION OF EARTH OBSERVATION SERVICES AND IN-FIELD SENSORS A single-entry point solution for wine producers aiming to boost vineyards’ sustainability The project is developing innovative vineyard management solutions, integrating and improving existing solutions coupling satellite imagery with in-field sensors to increase the resolution and reliability of satellite information applied to the viticulture sector and specific wine-business operations. VitiGEOSS uses European Open Earth Observation Services (EOS) for the improvement of agriculture business operations at an economic, environmental and local level. VitiGEOSS goal is to contribute to a responsible production of wine, minimising the use of chemicals and offering tools for a better management and a greater sustainability www.vitigeoss.eu @vitigeoss_EU info@vitigeoss.eu CONTACT US: Rosa Araujo Eurecat, Spain Project Coordinator Phenological monitoring Automated system to better plan and organise the whole vineyard management. Weather & climate forecast Robust weather & climate forecast for decision making processes in the wine sector. Business & sustainability Resource optimiser and planner service capable to plan best timing for field operations. Disease management Forecasting the disease evolution to optimise the treatments and resources used. Crop status Satellite imagery for optimising irrigation, sampling or selective harvesting. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 862192 Consortium | poster |
The Echelle Visualization Tool (Working Title) Bryson Stemock (bstemock@nmsu.edu), New Mexico State University Purpose Status This project is inspired by the Keck Observatory HIRES Echelle Format Simulator. Community Survey to get YOUR input The Echelle Visualization Tool (EVT) will allow ARCES users to visualize their raw data before and during observing runs. The EVT will accurately display the position of each echelle order and each spectral line of interest as it will appear on the CCD. This will provide an intuitive visual aid as observers check their incoming data as the night wears on; an important asset when our brains our tired at odd hours of the night and morning. Source: Sarah Kovac and Candace Gray ●Code foundation written using gratings; will be adapted to mimic ARCES as development progresses ●Displays blaze wavelength and free spectral range for each echelle order ●Can identify unique wavelength ranges vs. wavelengths that are contained in multiple orders ●Takes an input spectral line list and displays the locations of each given line everywhere it is present in the echelle exposure ●Code written to allow for relatively simple adaptation if/when ARCES is replaced someday The purpose of this poster is to gather input from the APO community to inform the direction of the EVT’s development. Does this seem like a tool that you would use? What features would make the EVT a tool that you would use regularly? If you have any thoughts on how to make the EVT more useful to ARCES users, please take 3-5 minutes to fill out a survey using this link: https://forms.gle/K3iGauGrBq6amY8X9. Keck Observatory HIRES Echelle Format Simulator (link below) | poster |
Explore, observe, design Put three or four elastic bands around a tub, box or jar. Now explore ways to make different sounds. You could compare wide bands and thin bands – which produces a higher pitched note? What happens to the note when you stretch a band? Organise your selection of elastic bands into order – from high pitched to low to create a musical instrument. Hint – a tub often works better than a box because a box crumples. Draw a diagram and write instructions so that someone else can make an instrument that produces the same notes. Dogs can hear sounds that humans can’t. A dog whistle produces a whistling sound that is too high pitched for human ears. Elephants communicate with each other using ‘rumbles’. These are sounds that are too low pitched for our ears to pick up! Can you make Can you make music with elastic music with elastic bands? bands? | poster |
Which types of terms become more prevalent, persistant, and adapt th e most? Which terms maintain semantic stability and which have multipl e variations? How can topic modelling and word embedding help to identify terms, an d t o analys e narrativ e structure s a nd semantic changes in specialised texts? Besides Latin calques, transliterations, and borrowings, what are othe r method s o f creatin g neologisms ? A re there limits to neology? Research questions Methodology The starting point of the research is the question about the peculiarities of the vocabulary in medieval French in mathematical texts during the Middle Ages. The goal of the study is to identify the mathematical terminology, focusing on the analysis of neologisms, diachronic, diatopic, diaphasic variations, semantic links, lost notions, and hapax legomena. The research relies on a corpus composed of texts from three out of four disciplines of the quadrivium: arithmetics, geometry and astronomy. The texts used are in edited and manuscript forms. MATHEMATICS VOCABULARY IN MIDDLE FRENCH (13th-16th centuries) Summary Results and conclusion IMAGES : NICOLAS DU PUY, PETIT COMPOST EN FRANCOYSS Corpus compilation. It involves the collection of edited and transcripted manuscripts. NLP analysis. We use topic modelling to analyse the narrative structure an d wor d embeddin g t o detec t semant ic peculiarities. Linguistic analysis. By means of the study of identified occurrences in ou r corpus . Dua l approach : linguisti c c o-tex t o f occurrence s an d narrati ve context of their appearance. This research focuses on under-studied elements in medieval linguistics - neology and terminological variations. In addition to the traditional textometric approach, we experiment with the use of computational techniques. Consequently, the novelty of the work lies in the examination of the discipline’s under-studied phenomena through non- traditional methods. | poster |
Michel Electron Reconstruction Using a Novel Deep-Learning-Based Multi-Level Event Reconstruction in ICARUS Yeon-jae Jwa on behalf of ICARUS Collaboration 1. Muon Decay-at-rest and Michel Electrons 2. Michel electrons in ICARUS Liquid Argon Time Projection Chamber 3. Deep-Learning based event reconstruction 4. Michel electron selection in ICARUS ●Michel electrons, produced by the decay-at-rest of cosmic-ray muons, have a well understood energy spectrum ranging up to ~50 MeV. ●Michel reconstruction demonstrates the detector’s capability in low-energy electron reconstruction. ●ICARUS is 600T Liquid Argon Time Projection Chamber (LArTPC) situated on the Fermilab beamline, receives abundant cosmic-ray muons. ●The energy loss of Michel electrons in argon has two contributing parts; electron ionization and photon radiation. Ionization Radiation Candidate Michel is ●Within 3 cm distance to a track ●Attached at the end of the track ●At least 20 reconstructed voxels Candidate Michels are matched to true Michels. Primary ionization is defined after the selection by finding the closest cluster to the parent muon (using DBScan.) 5. Michel energy reconstruction MC sample: BNB+Corsika simulation, Data sample: on-beam Run2 6. References [1] Laura Dominé. (2023), “Deep Learning based LArTPC Event Reconstruction and Nonmagnetic Muon Sign Determination in the ICARUS Detector”, [Doctoral dissertation, Stanford University.], https://searchworks.stanford.edu/view/14656199 [2] Laura Dominé, Kazu Terao, “Scalable deep convolutional neural networks for sparse, locally dense liquid argon time projection chamber data”, Phys. Rev. D (2020), 102, 1, 012005 [3] SPINE github repository, https://github.com/DeepLearnPhysics/spine Figure 3. U-net network structure for voxel reconstruction. Source: [2]. Figure 1. Theoretically calculated Michel energy. Soure: [1]. Figure 2. Electron stopping power in Argon from tabulated ESTAR database. ●SPINE: framework developed for LArTPC 3D reconstruction. ●Voxels are classified as: shower-like/track-like/Michel-like/Delta-like/low energy-like using semantic segmentation. ●Reconstructed voxels are further grouped to fragments/particles/interactions. Figure 4. Full reconstruction chain in SPINE. Source: [3] ●Summed ADC is translated to energy [MeV] after applying calibrations. (See poster #156 for more details on calibrations). ●Fractional energy resolution ○Ecorr= (Erec-β)/α, where α: slope, β: y-intercept from linear fit of (x,y: Etrue, Ereco). ○Eres = (Ecorr-Einit)/Einit, Eres is binned by Einit and fitted to Gaussian. True Michels Candidate Michels Attached to muon 37042 34582 Matched 32460 32460 Selection efficiency/purity: 87.63 %/93.86 % See poster #280 for more details on SPINE. See poster #108, #156 #280, for more analyses using SPINE. ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress 7. Acknowledgement This work was supported by the Department of Energy, Contract DE-AC02-765F00515. | poster |
Heterosynaptic plasticity rules induce small-world network topologies James McAllister, John Wade, Cian O’Donnell Intelligent Systems Research Centre, Ulster University Introduction Heterosynaptic plasticity is a form of ‘off-target’ synap- tic plasticity where unstimulated synapses change strength. Here we propose that one purpose of heterosynaptic plastic- ity is to encourage small-world connectivity [6, 7]. We com- pare different plasticity rules in abstract weighted graphs, finding that they yield distinct network architectures. Heterosynaptic plasticity Heterosynaptic plasticity is where synapses that were not directly activated undergo weight changes. Figure 1. Illustration of homosynaptic and heterosynaptic plasticity It can assume either a cooperative or competitive role in the alteration of synaptic weights (Figure 2). Cooperative Competitive Figure 2. Cooperative (left) and competitive (right) directions of weight change in heterosynaptic plasticity Heterosynaptic plasticity can operate locally on single den- drites at neighbouring spines, or across neurons and whole networks [4]. Method: Heterosynaptic plasticity network model Figure 3. Cases for weight updates in model Each edge is either (1) between two active nodes , (2) between one active and one inactive node, or (3) between two inactive nodes . Based on these cases, we define the update rules: R1 = wi,jn+1 = wi,jn + η1(1 −wi,jn) Case (1) wi,jn+1 = η2wi,jn otherwise R2 = wi,jn+1 = wi,jn + γ1(1 −wi,jn) Case (1) wi,jn+1 = γ2wi,jn Case (2) wi,jn+1 = γ3wi,jn, Case (3) R3 = wi,jn+1 = wi,jn + κ1(1 −wi,jn) Case (1) wi,jn+1 = wi,jn + κ2(1 −wi,jn) Case (2) wi,jn+1 = κ3wi,jn, Case (3) where R1 is a homosynaptic rule, and R2 and R3 are versions of competitive/cooperative heterosynaptic rules. ηi, γi and κi are learning parameters. We set η1 = γ1 = κ1 = 0.2 η2 = 1 −η1 = 0.8 η2 = γ3 = κ3 = 0.8 γ2 = 1 −γ1/2 = 0.9 κ2 = κ1/2 = 0.1 Method: Activity patterns We define the activity patterns of the network based on different Beta distributions (with varying parameters α, β). This determines the probability of each node being active. Network synchrony, firing rates, spike bursts and synaptic weights follow a log-normal distribution (Fig 4) [3], which we can partially replicate with beta distributions (Fig 5 blue line), as well as examine other less realistic activity patterns. Figure 4. Log-normal distribution of neural activity (Petersen & Berg, 2016) Figure 5. Example Beta distributions α = 1.5, 4, 4; β = 4, 1.5, 4 Method: Graph theory measures Weighted clustering coefficient: ˜C = Z 1 0 Ct dt where Ct = C(At) for At ij = 1 if wij ≥t and 0 otherwise. C(i) = |{ejk : vj, vk ∈Ni, ejk ∈E}| ki(ki −1) Average shortest path length (Dijkstra’s algorithm) L = 1 n(n −1) X i,j∈V i̸=j dij Small-world measure ↓ Small-world topologies A small-world network [7] has high degrees of clustering & low average shortest path length. σ = C/Crand L/Lrand > 1 Results Below is a simulation of how the network characteristics evolve under the homosynaptic (R1) and heterosynaptic (R2 & R3) plasticity rules over 100 timesteps. Figure 6. Graph theory measures for the three rules (N = 50 nodes) Given the probability distribution of activity, we can find a closed form solution for the weight matrix, which saves numerical simulations: R1: w∞ i,j ≈ η1pij 1 −(pij −pijη1 −pijη2 + η2) R2: w∞ i,j ≈ pijγ1 1 −(pij(1 −γ1 −2γ2 + γ3) + qij(γ2 −γ3) + γ3) R3: w∞ i,j ≈ (pij(κ1 −2κ2) + qijκ2) 1 −(pij(−1 −κ1 + 2κ2 + κ3) + qij(1 −κ2 −κ3) + κ3) where pi,j is the probability of node i and node j being active, and qi,j is the probability of node i or node j being active. Figure 7. Weight matrices for example network of 20 nodes Results continued Small-world measures across network sizes Figure 8. Small-world measures across different sizes of networks Beta distributions activity & small-world measures Figure 9. Average small-world measures across different activity distributions (N=100) Distribution of | poster |
Inferring biased allele expression across the genome Kimberly C. Olney1, Line Sko?e2, Ramus Nielsen3, Melissa Wilson Sayres1,4 1School of Life Sciences, Arizona State University, Tempe, Arizona 2Bioinforma<cs Center, Department of Biology, University of Copenhagen, Copenhagen 3Departments of Sta<s<cs and Integra<ve Biology, University of California, Berkeley, Berkeley, CA 4Center for Evolu<on and Medicine, Arizona State University, Tempe, Arizona Background When an individual’s two copies of an autosomal gene are expressed in unequal propor<ons the gene is said to be subject to biased allele expression. Biased allele expression has been shown to play a role in diseases like breast and ovarian cancer1. The ability to infer if a gene is subject to biased allele expression can improve our understanding of the molecular basis of disease. When modeling biased allele expression from RNA-‐Seq data it is important to take into account several sources of bias2. Factors that may affect the analysis of biased allele expression include: 1) reference mapping; 2) SNP type bias; and, 3) over-‐dispersion of read counts. Biased allele analysis pipeline References 1. Rijlaarsdam MA, et al. PLoS ONE. 2015;10: e0122146..0122146 2. Lappalainen, T. et al. Nature 501, 506–511 (2013). Acknowledgments Startup funds from the School of Life Sciences and The Biodesign Ins<tute to MWS Simulated data Figure 2. Method for inferring allele-‐specific expression. We test three different methods, and variable filtering criteria, for their specificity and sensi<vity to capture biased allele-‐expression. Figure 3. Simulated quanWle-‐quanWle plots. Minus log10 of the simulated and expected p-‐values. Expected values assume no biased allele expression. 300 genes, 30 depth coverage, and 5 SNPs. In order the: 1. SNP-‐wise binomial test are shown in red; 2. binomial-‐based logisWc regression test are shown in orange; and, 3. binomial-‐based logisWc regression test with over-‐dispersion corrected for are shown in green. Figure 3. Autosomes of 89 CEU populaWon data and various filtering Minus log 10 of the observed p-‐values are plo_ed against the expected corresponding quan<les under the null hypothesis of no allelic imbalance. The p-‐values for the SNP-‐wise binomial test for the filtered heterozygous sites in 89 CEU samples are shown in red. P-‐values for our model are shown in green. Figure 4. StaWsWcal power. We test power to detect biased allele expression under (A) variable depth of coverage per gene and (B) variable number of SNPs per gene. Plo_ed numbers of the frac<on of p-‐ values smaller than 0.05 divided by the number of tests to obtain Bonferroni correc<on for mul<ple tes<ng. Based on simulated count data for 300 genes, with 150 genes subject to balanced expression and 150 under biased allele expression. Figure 1. Biased allele expression. The difference in read counts could be biologically meaningful or could be due to technical variance in sequencing and mapping. hg19 reference 89 Europeans (CEU) Methods 3. LogisWc regression with over-‐dispersion Filtering 2. LogisWc regression without over-‐dispersion 1. SNP-‐wise binomial test SNPs per gene 2 3 4 Sequencing depth 20x 30x 40x Mapability file from UCSC Protein coding gene annotaWon hg19 Genotype 1000Genomes Transcriptome Geuvadis 89 CEU individuals ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● 0.0 0.5 1.0 1.5 2.0 2.5 0.0 0.5 1.0 1.5 2.0 Logistic regression with overdispersion Expected −log10(p−value) Observed −log10(p−value) ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● | poster |
Enhancing Interactivity and engagement to the Science Gateway Community Institute Workforce Development Site 2016-2017 :: Disaiah Bennett, Tatyana Matthews, Jefferson Ridgeway :: Mentor: Mr. Jeff Wood :: Dr. Linda B. Hayden, SGCI Workforce Development :: Center of Excellence in Remote Sensing Education FUTURE WORK | ACKNOWLEDGEMENTS | METHODOLOGY | ANALYSIS | CONCLUSION | ABSTRACT | The Center of Excellence in Remote Sensing Education and Research (CERSER) on the campus of Elizabeth City State University is a founding member of SGCI led by San Diego Supercomputing Center and the Science Gateways Community Institute (SGCI). One of the five areas of SGCI is the Workforce Development led by Dr. Linda Hayden. Workforce Development aims to nurture the next generation of gateway users and developers and engage the potential of students from underrepresented groups. As science today grows increasingly computer based, it poses challenges and opportunities for researchers. Scientists and engineers are turning to gateways to allow them to analyze, share, and understand large volumes of data more effectively. The existence of science and engineering gateways and the sophisticated cyberinfrastructure (CI) tools together can significantly improve the productivity of researchers. Most importantly, science gateways can give uniform access to the cyberinfrastructure that enables cutting-edge science. The goal of the web development team was to increase the interactivity of the SGCI Young Professionals site to attract potential members and disseminate information. This was completed utilizing WordPress Widgets to provide graphical and interactive components. Bootstrap components (HTML, CSS, and JavaScript) were also researched for their inclusion into the current WordPress Content Management System (CMS) and the future Liferay CMS. WordPress.org In order to implement components from bootstrap, it was important to first develop a bootstrap theme. The first step is to then set up a server via either MAMP (for Macintosh operating systems), LAMP (for Linux operating systems), or WAMP (for Windows operating systems). The AMP represents, Apache, MySQL, and PHP. MAMP/LAMP/WAMP can be used as “local servers that are used while developing PHP sites. Using these servers, programmers can test a website locally before they upload it to the main server” [13]. MAMP was used for this research due to team members using a Macintosh operating system. One has to then download WordPress.org in order to install WordPress.org on their PC/laptop. Furthermore, the team members followed the tutorial provided by LyraThemes entitled, “How to develop a WordPress Theme Using Bootstrap (Part 1)” [3]. After setting up the MAMP server, the team had to download Bootstrap and place the Bootstrap CSS, JavaScript(JS), and font directories within the WordPress directory. After MAMP was properly configured and activated, the team members were able to see a live Bootstrap, responsive design WordPress blog post. Soliloquy Due to SGCI not utilizing a Bootstrap theme for WordPress.org, another method of implementing Bootstrap-like components in a WordPress theme was explored. Of all of the plugins that were researched that implemented bootstrap-like components, the plugin Soliloquy was used based on its ease of use and its previous installation provided by SGCI. Soliloquy is defined on the plugin website “as the best responsive image slider for WordPress…[and]...will always look great on all devices (mobile, tablet, laptop, and desktop)” [11]. Image Hover Alongside the Soliloquy plugin, the team members also searched for a plugin that would replace the textual links on the SGCI Young Professional’s Network website and make it more inviting for users. The plugin found by the team was Image Hover Effects Pro. Image Hover Effects Pro allows the user “to add 40+ hover effects to images with captions” [4]. The installation and activation of the plugin is the same as Soliloquy. A shortcode | poster |
What are the perspectives of professionals working as part of a multidisciplinary autism team on strengths-based autism diagnostic assessment? What a strengths-based autism diagnostic assessment could look like Potential pros and cons of this type of assessment it has sort of stuck with me that we have picked apart what they [clients] couldn't do, and that there needs to be a way that actually doesn't rip someone's self-esteem to shreds the main problem of doing just like a strength- based assessment, is that a lot of things like getting an EHCP [education, health and care plan], and getting those kind of do rely on you what the child's are reports highlighting difficulties would be absolutely removed from the vocabulary of my team 'disorder' Interviewing professionals who work with children and young people to find out what they think about strengths-based autism diagnostic assessment Emma Pritchard & Jenny L. Gibson RESEARCH QUESTION METHODS INTRODUCTION Autistic people have reported dissatisfaction with autism diagnostic assessment, with the focus on deficits being a key issue. Rather than focusing on deficits, the neurodiversity paradigm advocates for a holistic view of difficulties, differences, and strengths. We want to find out how professionals can apply a neurodiversity-informed perspective to diagnostic assessment. A way of thinking called a 'strengths-based approach' could help with this. INSIGHTS Here, I share some early analytic insights based on familiarisation with the data- this is a work in progress Overall, professionals viewed a strengths- and needs-based assessment as important. Some talked about changing the language used in assessment and reports. Professionals think assessing strengths can be beneficial both during and after assessment e.g. self-esteem, support. Resource limitations and concerns around access to support are key issues. @EmmaPritchard95 ejp81@cam.ac.uk NEXT STEPS Finish analysis. The findings could highlight new ways for professionals to carry out assessments that better align with autistic people's needs. Interview topics: Qualitative method of analysis called reflexive thematic analysis - to help identify patterns relating to the professionals' views. the study on the Open Science Framework (Scan the QR code). Semi-structured interviews with involved in autism diagnostic assessment for children and young people. with autistic adults and parents/caregivers of autistic people to refine the interview questions. Pre-registered Consultation 19 professionals | poster |
Spatial and temporal variability of interactions in pea-oats mixed cropping on field-scale: Yield stability and nutrient use Julian Zachmann1, Iman Raj Chongtham2, Simone Graeff-Hönninger1, Erik Steen Jensen2, Sebastian Munz1 1Institute of Crop Science, University of Hohenheim, Stuttgart, Germany 2Department of Biosystems and Technology, Swedish University of Agricultural Sciences, Alnarp, Sweden Contact: julian.zachmann@uni-hohenheim.de Introduction - Cereal-grain legume mixtures have the potential to increase yield and cereal grain protein concentration and stabilize yields, particularly on fields where N is a limiting resource (Bedoussac et al., 2015). - Farmers’ fields may have a high heterogeneity in soil characteristics which influences spatial yield potential. According to the principle of “Ecological Precision Farming”, individual plants in mixed cropping can naturally adapt on a very small scale to a given heterogeneity resulting in higher yield stability, given the complementary use of resources (Jensen et al., 2015). This adaptation of cereal-legume mixtures to soil heterogeneity is investigated on a pea-oats mixture grown in Germany and Sweden. Main hypothesis are: - Mixtures are able to adapt to heterogeneity more efficiently than their respective sole crops by suppressing weeds and producing higher and more stable yields. - Mixtures use nitrogen more efficiently and oats achieve a higher grain protein content. - In mixtures, species can be differentiated by remote- sensing and their relative canopy cover can be determined. Methods In Germany, a two-year experiment (2018, 2019) on fields with a gradient in slope was established. Preliminary experiments showed a significant correlation between electromagnetic conductivity (EC) and soil clay-content as indicator for possible heterogeneity, e.g. in water availability. Sole and mixed crops were sown in replicated, parallel strips along the slope of the field. Sowing ratio in mixture was 50 % of oats sole crop (160 seeds m-² in mix) and 75 % of pea sole crop (60 seeds m-² in mix). No use of chemical plant protection. At maturity, 120 above ground samples (1 m²) were taken. Parameters of crops (e.g. thousand kernel weight and protein concentration) and soil (e.g. mineral nitrogen, phosphorus, clay content) will be measured in stored samples after yield analysis. Results - In intercropping (IC), mean oat grain yield was 3999 kg ha-1 compared to 5328 kg ha-1 in oats sole crop (SC) stripes, although oats crop density was only 50 % in IC (Figure 1). - Pea grains yielded 3400 kg ha-1 in SC and only 891 kg ha-1 in IC. - In IC, oats developed 36 % more shoots with panicles and peas had 43 % less pods per plant meanwhile thousand kernel weight did not change significantly. - Yield variation was high for pea in IC, medium for pea in SC and most stable for oats and total IC yield. - Differences in EC did not explain the variability in yield, tested for each cropping system. - Although there was no weed control, only little amount of weed biomass was found in oats SC and IC, meanwhile SC pea had a considerable higher weed biomass (Figure 2). Discussion and Outlook Oats are very plastic in tillering and have a high competitive potential (Sarunaite et al., 2013). Thus, oats were also suppressing the pea, resulting in lower pod production and yield. The higher yield stability in intercrops can be affiliated to the compensation potential of mixture partners. For further analysis of the variability, stored soil samples will be analyzed (e.g. nutrients, clay content and pH) and specific information like elevation and soil compaction will be considered. Fig 1. Grain yield of different cropping systems, hand harvested at UHOH in 2018. Bars headed with same capital letters are not significantly different (p<0.05). Error bars indicate standard error (n=120). CV is Coefficient of Variation. Fig 2. Dry matter of weeds biomass at crop maturity at UHOH in 2018. Bars with same capital letters ar | poster |
KNUST www.knust.edu.gh A SMART WEARABLE FALL GUARD SYSTEM FOR OLDER ADULTS K.B Osei 1 A. K. Asare Dakwa 1 E. Owusu 1 J.M. Ansah 1 I. Acquah, PhD *1 * iacquah.coe@knust.edu.gh 1 Department of Computer Engineering, College of Engineering Kwame Nkrumah University of Science and Technology (KNUST), Ghana INTRODUCTION METHODS Fig. 5: Graphs of Falls, ADLs and stationary motions respectively Fig. 1: Design Concept RESULTS The dataset was split into training and testing data; eighty percent training data and twenty percent testing data. Overall, we divided the data into three categories of motion so that the model we develop can classify these motions. These were the Stationary, Fall, and Activities of Daily Living (ADL) motions. These motions were presented graphically and were plotted based on accelerometer, gyroscopic and magnetometer values. DISCUSSION The simulation results and live demonstrations showed our fall detection model's reliability and effectiveness. The Arduino IDE’s serial monitor outputs precise separation between the various motion states confirming the model's capacity to recognize falls and distinguish them from normal activities. The addition of the alert system also emphasizes the applicability of our strategy in real-world situations as we targeted elderly people in nursing environments. This embraces the primary goals of this project. Future work should look at protecting other vital parts of the body which are also prone to fall injuries. Again, user-friendly interfaces, such as touchscreen displays or voice prompts can be incorporated, to provide users with real-time feedback CONCLUSION Our wearable fall guard system has proven its capability to precisely detect falls and distinguish them from ordinary activities via thorough development and optimum testing. With the help of the Edge Impulse platform, a strong machine-learning model was made possible, and when imbibed into our Arduino microcontroller, allowed for real-time analysis of motion data and quick action in the event of a fall. The system's ability to deliver prompt help and lessen the potential effects of falls is brought about by the seamless integration of sensory information, intelligent inference, and immediate alarm activation. REFERENCES 1. "Statista," [Online]. Available: https://www.statista.com/statistics/1183936/number-ofpeople- aged-65-years-and-older-in-ghana/. [Accessed 22 February 2023]. 2. "WHO global report on fall prevention in older age," [Online]. Available: https://www.who.int/publications/i/item/9789241563536 . [Accessed 23 February 2023]. 3. R. M. a. N. B. Y. Soliman, "Falls in the Elderly Secondary to Urinary Symptoms," vol. 18, no. 1, p. 28, 2016. Department of Computer Engineering – Biomedical Engineering Program mail: compeng@knust.edu.gh compengknust Aims/objectives. This project aims to: • Develop a wearable device that accurately detects falls using machine learning algorithms. • Design protective hip pads to cushion the impact of falls. • Evaluate the system's performance in real-world conditions. The world is experiencing a rapidly aging population. In Ghana, the number of individuals aged 65 and over is steadily increasing[1]. Falls pose a significant health risk to this vulnerable group, leading to severe injuries, reduced independence, and a lower quality of life[2][3]. Despite the growing prevalence of falls among the elderly, current fall detection systems suffer from limitations such as low accuracy, high false alarm rates, and reliance on cumbersome devices. These challenges hinder their widespread adoption and effectiveness in preventing fall-related injuries. Our project aims to address these limitations by developing a wearable, user-friendly fall detection system. By combining advanced machine learning algorithms with comfortable, protective hip pads, we seek to accurately detect falls and mitigate their impact. Our research is crucial for improving the safety and well-being of the elderly population. | poster |
LATEX TikZposter Collective effects in driving the 229Th nuclear transition Brenden S. Nickerson & Adriana P´alffy Max-Planck-Institut f¨ur Kernphysik Collective effects in driving the 229Th nuclear transition Brenden S. Nickerson & Adriana P´alffy Max-Planck-Institut f¨ur Kernphysik Abstract The high accuracy of atomic clocks lies behind the success of the Global Positioning System, which requires synchronization of orbiting satellites for triangulation. More precise clocks are desirable for challenging Einstein’s theory of general relativity or for Earth-observation satellites tracking the sea level, and would generally allow to push the bounds of observable physics. The unique lowest transition in the 229Th nucleus with frequency in the vacuum ultraviolet (VUV) range and very narrow line-width promises enhanced precision and amazing stability [1]. This level is a nuclear isomeric state at approx. 7.8 eV that can be reached by VUV lasers. A very exact measurement of the isomeric transition energy has been elusive, with the first confirmation of the level decay coming only recently [2]. Here we investigate the possibility to exploit collective effects in order to design a more sensitive nuclear excitation scheme in the process of scattering of light through a Th-doped crystal. The crystalline environment enforces the M¨ossbauer regime, allowing for recoil-free emission and absorption and collective behaviour [3]. By taking advantage of such effects we aim to resolve not only the transition energy but provide a clear signature of the excitation. Introduction to 229Th ⇒The isotope 229Th bridges atomic and nuclear physics with its unique long-lived nuclear excited state with the energy of 7.8 eV [4] ⇒The advantages of this nuclear transition are its very narrow width, the stability to external perturbations and an accessible frequency within the VUV region, rendering it a candidate for a nuclear clock system (Th Standard at 10−19 [5]). ⇒Measurement of the isomeric transition energy has been elusive with the first direct measurement coming only recently [2]. 5/2+ 7/2+ 9.2+ 3/2+ 5/2+ 7/2+ 0 42.43 97.13 71.82 29.19 0.0078 42.43 54.70 25.31 29.39 42.63 29.18 E [keV] 3 6 9 12 15 18 21 24 27 30 0 0.2 0.4 0.6 0.8 1 ⇡ 3⇡ 5⇡ 7⇡ 9⇡ ⌦t ⇢ee 3 6 9 12 15 18 21 24 27 30 0 0.2 0.4 0.6 0.8 1 ⇡ 3⇡ 5⇡ 7⇡ 9⇡ ⌦t ⇢ee 0 0.5 1 1.5 2 2.5 3 3.5 4 ·10−7 10−2 10−4 10−6 10−8 10−10 10−12 t ⌦2/⌦2 0 ∂tˆρ = 1 i¯h[ ˆH, ˆρ] + ˆρr 1 c∂tΩ+ ∂zΩ= iηρeg Ωij = ⟨i|d|j⟩· E ¯h mg + 1 2 −1 2 me −3 2 −1 2 + 1 2 + 3 2 =14.4 keV 57Fe Ig = 1 2 Ie = 3 2 ⌦ Coherent Driving of Thorium Nuclei ⇒Th doped in CaF2 crystal enforces the M¨ossbauer regime, where CaF2 is trans- parent at the energy required to drive the Th isomeric transition. ⇒Based on the polarity of the laser chosen we can probe different transitions. Seen to the right is the quadrupole level splitting of 229Th in 229Th : CaF2 along with the two and three level systems investigated in [3]. ⇒Driving the two level system results in an exponentially decaying intensity profile (a) which is sensitive to ∆on the order 107Γ (1 kHz) but does not possess a unique spectra. ⇒The addition of a coupling laser allows us to drive a second transition which introduces characteristic beating signature of the isomeric excitation (b). Fitting experimental data can determine ∆and therefore the 229gTh →229m Th transition frequency to a precision of 105Γ (10 Hz). Outlook ⇒With NFS in mind, we can change the level scheme of interest by looking at different host crystals and structured samples. ⇒Applying a magnetic field can give the opportunity to provide an signature that is even more sensitive the detuning parameters. M¨ossbauer Nuclei, NFS and Transition Energy ⇒229Th doped in a VUV transparent crystal enforces the M¨ossbauer regime, al- lowing for recoil free emission when driving the nuclear transition. ⇒Nuclear Forward Scattering (NFS) has been used successfully to identify nuclear transition energies in the well studied 57Fe as well as a variety | poster |
Innovative Research for a Sustainable Future www.epa.gov/research Madison Feshuk feshuk.madison@epa.gov ORCiD 0000-0002-1390-6405 Session Title: Computational Toxicology II Abstract Number/Poster Board Number: 4660/P706 Capturing prenatal developmental toxicity data using the Data Collection Tool (DCT): Pilot curation summary Madison Feshuk1, Sean Watford2, Saranagapani Addanki1, Whitney Fies3, Jessica Wignall3, Amar Singh1, Katie Paul Friedman1 1 Center for Computational Toxicology and Exposure, ORD, US EPA, RTP, NC, 2 Center for Public Health and Environmental Assessment, ORD, US EPA, Washington, DC 3ICF, Fairfax, VA History & Current Workflow ToxRefDB contains in vivo data from over 5000 animal studies for over 1000 chemicals. This database was developed via manual curation. The data collection tool (DCT) is an Oracle APEX software developed for curation of additional legacy documents with enhanced quality control and data provenance capabilities. The DCT includes: • Document allocation, curation and workflow management among users, and management review with data conflict resolution, resulting in a record that directly links quality-controlled curation to source documents. • Curation of basic study design metadata, dose-response, treatment- related and critical effects, and endpoint testing status information (with controlled vocabulary developed for ToxRefDB). • In vivo study results inform toxicity predictions as training data or may be used to build scientific confidence in the performance of new approach methodologies (NAMs). • NAM and animal study data need to be computationally accessible and interoperable. • An application-driven curation workflow was created to support expansion of the chemical and study data coverage in the Toxicity Reference Database (ToxRefDB). As curation of hundreds of additional DERs and study types (including chronic, subchronic, and multi-generational reproduction) with the DCT continues, this pilot dataset will be used to construct a sustainable pipeline for loading new legacy curations into ToxRefDB. These DEV studies will be reevaluated to understand their value added when compared to other DEV studies in future ToxRefDB releases. With ongoing curation, ToxRefDB will become a better resource for scientists and the interested public to access thousands of animal toxicity testing results, which is a crucial component in NAM validation to ultimately achieve reductions in animal testing. Rationale Disclaimer: This poster does not necessarily reflect U.S. EPA policy Figure 1: Inside a DCT Curation: The study wizard navigation bar displays the sections of the curation workflow: Chemical & Composition, Study, Dose, Dose Treatment Group, Dose Treatment Group Effect, and Observation. The Chemical & Composition page (displayed) features a document viewer that allows curators to view documents on a new tab within their internet browser. Results Conclusions Future Directions Acknowledgements Chemicals Studies Treatment Groups Treatment Groups with Effects Effectsa Critical Effectsb Unique Effectsc Unique Critical Effectsd Total 36 72 588 364 2079 673 155 119 Rat 35 35 290 183 1186 273 95 84 Rabbit 34 34 278 173 829 170 82 58 Mouse 3 3 20 8 64 6 22 5 Prenatal developmental (DEV) studies were selected for curation since they represent a current data gap for NAM development and validation. Data were extracted and made computationally accessible for 72 prenatal developmental (DEV) data evaluation records (DERs) from the EPA’s Office of Pesticide Programs (OPP). Dose Treatment Group Fetal F0 0 mg/kg/day 10 mg/kg/day 30 mg/kg/day 100 mg/kg/day Dose Fetal F0 Fetal F0 Fetal F0 Figure 2: DEV example of Dose Treatment Groups: As a prenatal developmental study design example, the number of doses administered (4) is multiplied by the number of treatment groups (2, dams and their litters) to determine the number of dose treatment groups (8) examined for effects at the time of sacrifice. Table A: Summary statisti | poster |
DETECÇÃO DE MUDANÇAS DA PAISAGEM COM DADOS LiDAR-ALS NO MUNICÍPIO DE PARAGOMINAS – PA ENTRE OS ANOS DE 2013 E 2017 Derica dos Santos Sousa, UDESC, Lages/SC, Brasil, derica@tuta.io; Felizardo Neto, UDESC, Lages/SC, Brasil, felizardo.neto@edu.udesc.br; Lucas Inácio, UDESC, Lages/SC, Brasil, lucasinacio1301@gmail.com; Veraldo Liesenberg, UDESC, Lages/SC, Brasil, veraldo.liesenberg@udesc.br. Introdução e Objetivos A expansão rápida de atividades agrícolas, exploração madeireira e outras ações antropogênicas têm impactado a cobertura florestal, resultando em perda de biodiversidade (FERREIRA; VENTICINQUE; ALMEIDA, 2005). O monitoramento dessas mudanças é importante para orientar esforços de conservação. O LiDAR-ALS é uma ferramenta eficaz nesse contexto, fornecendo informações tridimensionais detalhadas sobre a vegetação. Este estudo avalia a dinâmica da vegetação em Paragominas, Pará, entre 2013 e 2017, usando dados ALS para analisar a estrutura do dossel florestal. Metodologia Resultados e Discussões A comparação dos CHMs ao longo dos anos permitiu identificar áreas de supressão, regeneração e estabilidade, analisadas em diferentes resoluções espaciais (1m a 20m). Resoluções mais finas capturam detalhes localizados da estrutura florestal, enquanto resoluções mais amplas destacam padrões gerais de mudança. Essa abordagem multiescalar equilibra detalhe e abrangência espacial em grandes áreas florestais. Figuras e Tabelas Referências Bibliográficas FERREIRA, L. V.; VENTICINQUE, E.; ALMEIDA, S. O desmatamento na Amazônia e a importância das áreas protegidas. Estudos Avançados, v. 19, p. 157–166, abr. 2005. Conclusão A análise das mudanças da paisagem com dados LiDAR-ALS entre 2013 e 2017 no município de Paragominas evidenciou a importância do uso de técnicas de sensoriamento remoto para monitoramento ambiental. Os resultados permitiram identificar áreas de supressão, regeneração e estabilidade da vegetação em múltiplas resoluções espaciais, destacando a eficácia das resoluções mais finas para captar detalhes da estrutura florestal e das resoluções mais amplas para observar padrões gerais. Essa abordagem multiescalar possibilita uma compreensão abrangente da dinâmica florestal, sendo fundamental para apoiar estratégias de conservação, manejo sustentável e políticas públicas de preservação do bioma amazônico. Figura 1. Diferença no CHM P08 em 8 classes de altura de vegetação (a). Reclassificação em 3 classes de mudança, (-1) supressão, (0) estabilidade e (1) regeneração. a) b) Figura 2. Classes de mudanças por resolução – P11. | poster |
Community Registries (z.B. NFDI4Culture), allg. Suche Instit. Richtlinien, FAIR4RS, NFDI4Culture Guidelines u.a. Projekt- management, Software- managementplan NFDI4Culture Helpdesk, Foren, allg. Beratungs- angebote etc. GitLab, GitHub, Zenodo, Community Registries 01 Recherchieren - Gibt es schon eine (fast) passende Lösung? 02 Informieren - Best Practices und Leitlinien beachten 5 SCHRITTE ZU NACHHALTIGER(ER) SOFTWARE 03 Planen - Entwicklung vorbereiten und organisieren 04 Helfen lassen - Angebote für Unterstützung/Beratung nutzen 05 Teilen - Publizieren und Leistung anerkennen lassen CO-SPOKESPERSONS DES ARBEITSBEREICHS FORSCHUNGSWERKZEUGE UND DATENDIENSTE Dr. Lisa Dieckmann Dipl. Wirt.-Inf. Daniel Röwenstrunk MITARBEITENDE DES ARBEITSBEREICHS Dr. Martin Albrecht-Hohmaier Anne Ferger Franziska Fritzsche Sven Peter Astrid Probst Sabrina Ujkasevic Anastasia Wawilow KONTAKT https://nfdi4culture.de contact@nfdi4culture.de https://twitter.com/nfdi4culture Daniel Jettka Aleksander Marcic (inhaltl. verantw.) | poster |
C. Lazarou1,2, L. Wang3, A. Nikiforov3, C. Leys3, C. Anastassiou1,2, I. Topala4, A. S. Chiper4, I. Mihaila5, V. Pohoata4, P. Vogel6, A. Knodel6, B. Gilbert Lopez7, J. F. Garcia Reyes7, A. Molina-Diaz7, J. Franzke6 and G. E. Georghiou1,2 1 FOSS Research Centre for Sustainable Energy, Department of Electrical and Computer Engineering, University of Cyprus 2 ENAL Electromagnetics and Novel Applications Lab, Department of Electrical and Computer Engineering, University of Cyprus 3Department of Applied Physics, Ghent University, Belgium 4 Iasi Plasma Advanced Research Center (IPARC), Faculty of Physics, Alexandru Ioan Cuza University of Iasi 5 Integrated Center of Environmental Science Studies in the North-Eastern Development Region (CERNESIM), Alexandru Ioan Cuza University of Iasi 6ISAS—Leibniz Institut für Analytische Wissenschaften, Dortmund, Germany 7Analytical Chemistry Research Group, Department of Physical and Analytical Chemistry, University of Jaén (corresponding author email: lazarou.constantinos@ucy.ac.cy) • In this study, a two-dimensional axi-symmetric model has been developed to provide insight into the evolution of capillary helium plasma jet with and without the presence of oxygen admixtures and its interaction with a dielectric surface placed normal to the jet axis. • The model considers the gas mixing of helium and ambient air and the analytical chemistry between helium, nitrogen and oxygen species. • Experiments were performed in similar conditions as the simulations in order to get qualitative agreement between them. Understanding the evolution of a He and He/O2 capillary plasma jet This project has received funding from the European Union’s Horizon 2020 research and innovation programme under agreement No. 810686 Experimental Setup Results Acknowledgment Conclusions Introduction Theory and methodology Simulation domain • The gas dynamic model (GDM) is used to describe the flow of the helium jet in the ambient air [1]. The calculated profiles of the helium and air mole fraction and the mass average velocity are then fed into plasma fluid model (PFM). • The PFM uses the continuity equation in the drift diffusion approximation for the description of electrons and electron energy, and the multi-component diffusion equation for the description of the heavy species in the mixture (neutral, excited and ion species) [2]. • The equations of the PFM are coupled with the Poisson equation for the description of the electric field. Experimental Results Simulation Results Figure 1: Spatio-temporal evolution of the plasma bullet for (a) He and (b) He+O2 (1000 ppm) plasma jet. Time 0 ns corresponds to the plasma bullet just about the exit of the tube. The three dashed lines indicate the axial distance from the tube nozzle for z=0, 1 and 2 mm. Figure 2: Simulation results for the spatio-temporal evolution of the total ionization rate for (a) He and (b) He+O2 (1000 ppm) plasma jet. Time 0 ns corresponds to the plasma bullet just about the exit of the tube. The total ionization rate has units of mol/m3s. Figure 3: Simulation results of electron production rate in logarithmic scale for the He plasma jet. The plasma bullet is located at -0.75 mm from the tube exit. • The addition of oxygen admixtures in the helium gas promotes plasma bullet propagation on the axis of symmetry of the tube (instead off axis propagation for the pure helium plasma jet). • The simulation results show that the shape of the plasma bullet during its propagation is controlled by the generation of seed electrons in front of the streamer head. • For He/O2 plasma jets, the shape of the bullet remains sphere like because the seed electrons are mainly produced uniformly along the axis of symmetry in the helium channel, through Penning ionization of helium metastable species with the admixture of O2 molecules. • For the pure helium jet the bullet is torus shaped because seed electrons in the helium channel are mainly generated on the edges of the channel through | poster |
BD2K-LINCS DATA COORDINATION AND INTEGRATION CENTER Acknowledgements: This research was supported by grant U54HL127624 awarded by the National Heart, Lung, and Blood Institute through funds provided by the trans-NIH Library of Integrated Network-based Cellular Signatures (LINCS) Program (http://www.lincsproject.org/) and the trans-NIH Big Data to Knowledge (BD2K) initiative (http://www.bd2k.nih.gov). Correspondence: s.schurer@miami.edu The LINCS Data Portal and FAIR LINCS Dataset Landing Pages Abstract The LINCS Data Portal (LDP) presents a unified interface to access LINCS datasets and metadata with mappings to several external resources. LDP provides various options to explore, query, and download LINCS dataset packages and reagents that have been described using the LINCS metadata standards. We recently introduced LINCS Dataset Landing Pages to provide integrated access to important content for each LINCS dataset. The landing pages provide deep metadata for each LINCS dataset including description of the assays, authors, data analysis pipelines, and standardized reagents such as small molecules cell lines, antibodies, etc, with rich annotations. The landing pages are a key component to make LINCS data persistent and reusable, by integrating LINCS datasets, data processing pipelines, analytes, perturbations, model systems and related concepts as uniquely identifiable digital research objects. LDP supports ontology-driven concept search, free text search, facet filtering, logical intersection of filters (AND, OR), and list, table, and matrix views. LDP enables download of LINCS dataset packages, which consist of released datasets and associated metadata. LDP also provides several specialized apps including small molecule compounds and cell lines. A landing page facilitates interactive exploration of all LINCS datasets via several classifications. LDP is built on a robust API and is integrated with the MetaData Registry and interfaces with other components of the Integrated Knowledge Environment (IKE) developed in our Center. All LINCS datasets are also indexed in bioCADDIE DataMed. Amar Koleti1, 5, Vasileios Stathias1, 2, 5, Raymond Terryn1, 2, 5, Michele Forlin1, 2, 5, Dušica Vidović1, 2, 5, Caty Chung1, 5, Wen Niu4, 5, Caroline Monteiro3, 5, Christopher Mader1, 5, Avi Ma’ayan3, 5, Mario Medvedovic4, 5, Stephan Schürer1, 2, 5 1Center for Computational Science and University of Miami, Miami, FL; 2Department of Molecular and Cellular Pharmacology, University of Miami, Miami, FL: 3Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1215, New York, NY; 4Division of Biostatistics and Bioinformatics, Environmental Health Department, University of Cincinnati; Cincinnati, OH; 5BD2K LINCS Data Coordination and Integration Center LINCS Data Portal (LDP) http://lincsportal.ccs.miami.edu LINCS Datasets Small Molecules EBI services cross-references LINCS Small Molecules IDs LINCS Datasets in DataMed CLO LINCS Cell Lines | poster |
MORC2 Neurodevelopmental Disorder - a Mitochondrial Disease Masquerader Azzah Atiqah Ahmad, Sulekha Sivapatham, Chan Mei Yan Clinical Genetics Department, Hospital Kuala Lumpur. 1. OMIM® - Online Mendelian Inheritance in Man: MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 2; MORC2 (OMIM: 616661) 2. Guillen Sacoto MJ, Tchasovnikarova IA, Torti E, et al. De Novo Variants in the ATPase Module of MORC2 Cause a Neurodevelopmental Disorder with Growth Retardation and Variable Craniofacial Dysmorphism. Am J Hum Genet. 2020;107(2):352-363. doi:10.1016/j.ajhg.2020.06.013 3. Tchasovnikarova IA, Timms RT, Douse CH, Roberts RC, Dougan G, Kingston RE, Modis Y, Lehner PJ. Hyperactivation of HUSH complex function by Charcot- Marie-Tooth disease mutation in MORC2. Nat Genet. 2017 Jul;49(7):1035-1044. doi: 10.1038/ng.3878. Epub 2017 Jun 5. PMID: 28581500; PMCID: PMC5493197. References Differential diagnoses: • Leigh disease • Biotin-thiamine dependent basal ganglia disease • Viral encephalitis. Mitochondrial cocktail was prescribed and he showed an improvement in symptoms after initiation. • Dystonia resolved • Left sided weakness resolved • Swallowing improved • No more drooling • Able to swallow small amounts • Development forward progressing • Good head control in sitting position • Still unable to turn prone • Able to maintain tripod sitting posture • Pincer grip, object transfer • No speech MORC2 has a threefold function within the human body: • Epigenetic silencing by HUSH complex • Regulating ATP citrate lyase activity • Facilitating chromatin remodeling MORC2 encodes for an ATPase fundamental for epigenetic silencing by the human silencing hub (HUSH) complex. MORC2 mutations hyperactivates HUSH- mediated repression in neuronal cells CNS manifestations (eg: weakness, hyporeflexia, neuropathy) As MORC2 also binds to ATP citrate lyase which catalyses the formation of acetyl Co-A, this is the potential mechanism for mitochondrial-like disease features (Figure 2). MORC2 missense mutations • complex neurologic disorder • impaired motor and intellectual development, • hypotonia • poor overall growth • subtle dysmorphism • signs and severity are highly variable • hearing loss • pigmentary retinopathy • abnormalities on brain imaging, including cerebral or cerebellar atrophy, hypomyelination, and lesions in the basal ganglia or brainstem. Most common features of patients with MORC2 mutations (features in bold were also noted in the reported case) • Short stature • Microcephaly • Motor delay • Intellectual disability • Gait abnormalities • Hypotonia • Hyporeflexia Leigh syndrome-like lesions on MRI brain are present in approximately 28% of patients with MORC2 mutations. Discussion Conclusions REPLACE THIS BOX WITH YOUR ORGANIZATION’S HIGH RESOLUTION LOGO Introduction Mitochondrial disorders present in a myriad of ways. Tissues with the highest energy requirements are the most affected as mitochondria are the powerhouses of cells. Common organs affected include the brain, heart and skeletal muscle. Some conditions can mimic mitochondrial disorders in clinical presentation and radiological findings. Recognition of such conditions is important as accurate diagnosis is important for patient management and genetic counseling. Microrchidia CW-zinc finger type 2 (MORC2) gene mutations cause a newly described neurodevelopmental disorder with growth retardation and variable craniofacial dysmorphism (DIGFAN). The aim of this case report is to highlight the fact that other genetic conditions can masquerade as a mitochondrial disorder. Case description A 2 year-old Malay boy who was born to non consanguineous parents was referred for genetic evaluation of a possible Leigh syndrome. He was born at 36 weeks with birth weight of 1.9kg, and had a background of global development delay. Presented with • Hemiplegia • Dystonia • Neuroregression Physical examination • left upper motor neuron facial nerve palsy • left hemiplegia • hypotonia and hyporeflexia. Molecular anal | poster |
Johanna Vos1, Beth Biller1, Katelyn Allers2, Mariangela Bonavita1, Esther Buenzli3, Wolfgang Brandner3, Derek Homeier4,5, Thomas Henning3, Taisiya Kopytova3, Michael Liu6, E Manjavacas3,7, J Schlieder3,8 1University of Edinburgh, 2Bucknell University, 3MPIA Heidelberg, 4Universität Heidelberg, 5Université de Lyon, 6IfA Hawaii, 7IAC, 8NASA Ames Photometric Monitoring is a Key Probe of Weather Phenomena on Exoplanets Condensate Clouds in Exoplanet Atmospheres • The L/T transition is characterised by a J-band brightening as well as a dramatic blueward shift in the NIR color- magnitude diagram. • Directly imaged planets occupy the same temperature regime as L/T transition brown dwarfs, and were expected to exhibit similar atmospheric properties. • However most young exoplanets appear much redder in the near- IR than their brown dwarf counterparts at similar Teff,as shown in Fig. 1. Young, Isolated Brown Dwarfs: • Allow higher photometric precision than directly imaged planets • Young objects are likely to have higher variability amplitudes (Metchev et al. 2015). • By studying young objects we push further into the planetary mass regime. Condensate Clouds + Rapid Rotation Photometric Variability Photometric variability has been detected across the full L-T spectral range, with considerably higher variability amplitudes observed at the L/T transition. Directly imaged planets occupy the same temperature regime as L and T type brown dwarfs and are likely to exhibit similar variability. Main Objectives: • To discover the first weather patterns on planetary-mass objects. • To characterise these weather patterns via multi-wavelength follow-up monitoring. • Formation of condensate clouds in the atmosphere • Condensate clouds sink or break up. L Dwarfs @ 2100 K T Dwarfs @ 1200 K L0 L2 L4 L6 L8 T0 T2 T4 Spectral Type 0 1 2 3 4 5 Targets Fig. 2: Spectral type of objects observed. Fig. 1: Color-magnitude diagram of M, L, T brown dwarfs with directly imaged exoplanets plotted in colour (Liu et al., 2013). References Biller, B. A., Vos, J., Bonavita, M., et al. 2015, ApJ, 813, L23 Buenzli E. et al., 2012, Ap. J. L., 760, L31 Liu M. C. et al., 2013, Ap. J. L., 777, L20 Radigan J., 2014, Ap. J., 797, 120 Metchev, S. A., Heinze, A., Apai, D., et al. 2015, ApJ, 799, 154 Results and Future Prospects • High-amplitude variability detection (Figure 3) for the free-floating planet PSO J318.5-22 (Biller, Vos et al. 2015). • Multi-wavelength follow-up: • determine the rotational period • characterise vertical and horizontal cloud structures (Buenzli et al., 2012). • 4 tentative lower-amplitude variability detections (<5%), e.g. Figure 4. Fig. 4: Detrended light curve for a tentative variability detection shown in red. Sample reference star lightcurve shown in blue. Fig. 3: High amplitude variability detection for PSO J318.5-22. Reference star light curve shown in blue. (Biller et al. 2015) email: jvos@roe.ac.uk The First Search for Exoplanet Weather 0.96 0.98 1.00 1.02 1.04 JS 0 1 2 3 4 Elapsed Time (hr) 0.975 1.000 1.025 0.90 0.95 1.00 1.05 1.10 PSO J318.5-22 JS 0 1 2 3 4 5 Elapsed Time (hr) 0.95 1.00 1.05 • Constrain the fraction which show variability on rotational timescales. • Probe the effects of surface gravity on cloud structure via comparison with previous brown dwarf variability surveys such as Radigan et al. (2014). We are conducting the first statistically significant search for weather patterns on free-floating young planetary mass objects using the SoFI instrument at the New Technology 3.5m Telescope. Future Goals: | poster |
Oct. Nov. Dec. Jan. Feb. Mar. Apr. May 10 20 30 40 50 60 70 80 409 665 220 504 646 265 310 354 Updates number : 2013 October – 2014 May Data volume increase (raw text format only, in Mo) 40% 54% 6% Regularly Occasionally Not at all Oct. Nov. Dec. Jan. Feb. Mar. Apr. May 1866 2613 982 2127 2813 1230 1512 1430 Number of requests : 2013 October – 2014 May Average 2013-2014 Average 2012-2013 TWiki : A collaborative space of internal documentation ~ An efficient way to work together ~ The documentalists at Strasbourg astronomical Data Center treat publications to create content for the SIMBAD and VizieR databases. The publication treatment is quite complex and the ingestion process needs to be described. This requires precise knowledge and mutual support among the documentalists in interaction with computer engineers and astronomers. Documentalists at CDS have thought of an adapted way to organize and enrich their internal documentation. The “TWiki” collaborative space, recently reorganized and enriched, regroups documents about agreed-upon procedures and methods, directions for use of the software and tools, shared problems/solutions. It is a tool for sharing, preserving and enriching the common knowledge of the whole staff. E. Son, A. Eisele, A. Schaaff, E. Perret, M. Brouty, C. Bruneau, C. Brunet, M. Buga, F. Genova, S. Guehenneux, S. Lesteven, C. Loup, L. Miguel, M. Neuville, A. Oberto, P. Vannier, P. Vonflie, F. Woelfel Observatoire Astronomique de Strasbourg, Université de Strasbourg/CNRS, UMR 7550 An organization per boxes : ●Staff organization ●SIMBAD and VizieR databases ●CDS Tools (DJIN and COSIM) ●SIMBAD Dictionnary of nomenclature ●Astrophysics ●Computer science ●Useful links What kind of information can we find in the Twiki space ? ●General information ●Updating commands ●Meetings reports ●PDF documents and web links ●Follow-up of the work progress Documentalists Computer scientists Astronomers Edition : everyone can easily add, complete, correct and refine data. Home Page Shortcuts To the most used pages Links to pages... Contents The Twiki space on a day to day basis Common knowledge : the information is available for the wole staff One place to find the good information : it's easy and accessible Preservation of information, common memory Added value Normalisation of work practices Training of new staff and keeping track of the knowledge of retiring staff Someone struggles, fines a solution and shares it with everybody Work monitoring in real time for complex and shared tasks Save time Improve productivity and efficiency Number of requests Updates and volume increase Attending the meeting (Mo) 14 573 requests /8 months 3 373 updates /8 months + 92% Text data /1 year Use by the CDS staff (34 people) 1082 1822 Updates average : 422 /month (vs 172 /month last year) | poster |
Insight on Solar Flare Forecast With Explainable Deep Learning Grégoire Francisco [1,2], Dario Del Moro[1], Teresa Barata[2], João Fernandes[3], Sabrina Guastavino [4], Michele Piana[4] . [1] Department of Physics, University of Rome Tor Vergata , [2] IA, Instituto De Astrofisica E Ciências Do Espaço, University of Coimbra, [3] CITEUC, Geophysical and Astronomical Observatory, University of Coimbra [4] MIDA, Dipartimento di Matematica, Università degli Studi di Genova . Contact : gfrancisco@roma2.infn.it This research is part of the Space Weather Awareness Training Net- work (SWATNet) funded by the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 955620 This research is also part of the Comprehensive Space Weather Studies for the ASPIS Prototype Realization (CAESAR) project, sup- ported by the Italian Space Agency and the National Institute of Astrophysics through the ASI-INAF n.2020- 35-HH.0 agreement for the development of the ASPIS prototype of scientific data centre for Space Weather. Acknowledgements • Coronal images showcase a 24h-window forecasting power close to the magnetogram • Each atmospheric layer consistently used by atmospheric models and contributing to improved performances • Overall Explainability Methods couple with Deep Learning proved to be useful to : - help to gain confidence in models prediction and provide key information on the predictions quality - provide a purely data-driven approach to study and identify flare precursors - identify model weakness and help to find remedies • Polarity Sandwiches identified as potential new flare precursors (they could also be an artefact of the pretrained models) • We are developing an automatic segmentation tool of Polarity Sandwiches based on Mathematical Morphology to perform a more systematic analysis of their correlation to the flares • We are developing automatic detection tools of the other mentioned features to consolidate and generalize our statistical analysis • We are working on reproducing our approach on videos of the Corona to identify temporal/dynamic Coronal flare precursors Conclusions and future works Solar Flares are sudden and violent release of magnetic energy from the Sun’s atmosphere in the form of electromagnetic radiation bursts. Being able to forecast Solar Flares accurately is essential to mitigate the risks associated with Space Weather, but it has been proven to be particularly challenging. Recently, Deep Learning Methods (DLMs) captured the interest of many re- searchers in the field and new data-driven approaches to the problem have been developed. With Explainability Methods (EMs) we can reverse this data-driven approach to gather insight on the actual physics of the events. We apply EMs to DLMs trained on Solar Corona images which perform as well as models trained on Solar Photosphere magnetograms alone to forecast Solar Flares in a 24h forecasting window. In these preliminary results we confirm that our models efficiently learn known physical precursors, such as the presence of sigmoidal coronal structures, which are observational signatures of highly twisted and sheared magnetic fields in the Solar Corona. From this proof of concept we also verified that DLMs trained on Solar Corona images can be efficient to forecast Flares near the Solar Limb, where it is harder for models using magnetograms alone. Model combining magnetograms and images of the different layers of the Solar Atmosphere seem to provide the best performances. Abstract Method We use Convolutional Neural Networks (CNN) to perform binary forecasts of C-class and higher flares. We use the publicly available SDOBenchmark dataset consisting of 9000 AR crops covering Solar Cycle 24 peak (https://i4ds.github.io/SDOBenchmark/) . We split the training dataset in 10 folds by randomly separating AR numbers and perform 10 folds Cross-Validations (CV) to fine-tune and evaluate our models. We use two distinct sets of fold for | poster |
ON SAFE GROUND NGI.NO Transport behaviour of PFAS and immobilization approaches with regenerated waste products in large scale unsaturated lysimeters 1. Objective The transport of PFAS through the lysimeter column was heavily influenced by the weekly irrigation. Figure 2 a) summarizes the leaching of PFOS based on the exchanged pore volumes and b) the residual PFOS concentration in each lysimeter. With the start of the irrigation PFOS concentrations are lowered due to a dilution effect (Figure 2a). With the end of the irrigation PFOS concentrations in the leachate were increasing again. The total amount of PFOS which leached was increased by 14% up to 47% for the additional 1.6 and 3.5 L/week irrigation, respectively, compared to natural precipitation. Figure 2b presents a chromatographic like distribution of PFOS in the different lysimeter columns, and their different retentions at the end of the experiment. Michel Hubert*1,2, Björn Bonnet*3, Lutz Ahrens3, Hans Peter H. Arp1,2 1 Norwegian University of Science and Technology (NTNU), NO-7491 Trondheim, Norway. 2 Norwegian Geotechnical Institute (NGI), NO-0806 Oslo, Norway. 3 Swedish University of Agricultural Sciences (SLU), P.O. Box 7050, SE-75007 Uppsala, Sweden. Figure 1 – Lysimeter experiment at SLU, Sweden. Immobilization technologies aim to stabilize per- and polyfluoroalkyl substances (PFAS) within the soil to reduce and manage PFAS leaching. Two hurdles for their successful implementation exist. The first is that a detailed knowledge of PFAS transportation in the unsaturated zone is needed, both with and without the technical immobilization, under different conditions. The second is that many binders may have their own risks, such as anthracitic carbon associated with a high carbon footprint. This study investigates hereby the following aims: 2. Methods and Materials Natural precipitation vs. enhanced precipitation Reducing leaching of PFAS from hot spots Testing of novel, carbon sequestering biochars for PFAS stabilization Transport behaviour of PFAS in the unsaturated zone with changing climate 10 outdoor lysimeters were set up at SLU, Sweden (Figure 1). All lysimeters were packed with sandy soil spiked with 18 PFAS at concentrations found at typical AFFF contaminated sites. All lysimeters received the natural rainfall over the experimental time of 1 year. In addition, two lysimeter were weekly irrigated (1.6 L = 35 mm/h and 3.0 L = 64 mm/h, respectively). Different lysimeters contained different amendments, including 1% powdered activated carbon (PAC), 1% and 4% waste timber biochar (WT-BC), 1 and 4% sewage sludge biochar (SL-BC) (Sørmo et al. 2023). Leachate samples were taken weekly when available and section wise soil samples were taken after the end of the experiment. Figure 2 – a) Leaching behaviour of PFOS, b) residual PFOS in the soil for non-amended lysimeters. 3. Transport behavior of PFAS 4. Stabilization using waste derived biochars Figure 3 compares the stabilization of the environmentally friendly, waste derived biochars with the PAC lysimeter. 5. Conclusion For all tested amendments, the retardation increased with increasing –CF2 chain length. Furthermore, there is a clear headgroup dependency with retention increasing in the order of FTS > PFSAs > PFCAs. Compared to 1% PAC the biochar derived from waste timber (WT-BC) showed 30 to 40% total retention for shorter chain PFAS and 50% for longer chain PFAS. The sludge derived biochar (SL-BC) performed comparable better, with total retention for shorter chain PFAS in the range of 60 to 70% and 70 to 90% for longer chain PFAS. The increase of the amount of biochar mixed into the soil from 1 to 4% led to 5 to 10% higher PFAS retention. Figure 3 –PFAS stabilization [%] compared to the lysimeter amended with 1% PAC. Green shade identifies shorter chain and red shade longer chain PFAS. • PFAS contaminated hot spots are vulnarable to a changing rainfall and irrigation events. • Sludge derived biochar showed prom | poster |
0.0 0.1 0.2 0.3 10 12 14 16 18 20 22 C"PEAK /pF Time /h Primary drying 0.244 pF ≡2 g water Drying rate (dm/dt) ~ 0.3 g/h DRIED PRODUCT RESISTANCE (RP) DETERMINATION o C"PEAK from TVIS is proportional to the amount of ice; therefore it is estimated for drying rate (dm/dt) o Partial pressure of ice (PICE) and condenser (PCONDENSER) calculated from temperature of ice (TICE) and condenser (TCONDENSER) by using Clausius- Clapeyron derived equation -70 -60 -50 -40 -30 10 12 14 16 18 20 Temperature/oC Time / h Temperature of ice (TICE) Temperature of condenser (TCONDENSER) Shelf temperature (TSHELF) The Application of Through Vial Impedance Spectroscopy (TVIS) for Optimization Freeze-Drying Process Yowwares Jeeraruangrattana and Bhaskar Pandya Leicester School of Pharmacy, Faculty of Health and Life Sciences, De Montfort University Supervisors: Professor Geoff Smith and Dr Irina Ermolina TVIS TECHNOLOGY In-line monitoring system for the freeze drying process consisting of: oFreeze-drying vial with external electrodes oPass through for cabling oExternal Impedance spectrometer. TVIS TECHNOLOGY PRINCIPLE Process analytical technology based on impedance spectroscopy o Electrical impedance determines the ability of materials to conduct electricity under an applied voltage . o Impedance is a function of dielectric and conductive properties and therefore the physical state of vial and its contents. o Principal parameter effecting measured impedance is resistance/conductivity of sample within the vial. o Changes in electrical parameters mirror the condition of the sample throughout the lyophilisation process. o The capacitance spectrum is related to the resistance/ conductivity and capacitance of the vial contents. o Data viewing software (LyoView ™) identifies the peak frequency (FPEAK) and the peak amplitude (CʺPEAK) in the imaginary part of the capacitance spectrum o FPEAK can be used to monitor phase behaviour (ice formation, glass transitions) and product temperature o CʺPEAK can be used to monitor the amount of ice remaining during primary drying, from which the drying rate and the end point may be determined. TVIS ADVANTAGE 1.Non-invasive, real time full cycle lyophilisation monitoring including : o Cooling rate, Freezing and Annealing o Primary and Secondary Drying end point 2. Optimization of the primary drying process by: o Heat Transfer Coefficient (KV) Determination o Dried Product Resistance (RP) Determination 3. Can be applied in standard freeze dryers 4. Integrated, bench top, single vial, TVIS enabled analytical freeze dryer “Non-invasive, real time lyophilisation process monitoring would increase process understanding and accelerate development of stabilized biopharmaceutical formulations at room temperature.” 101 102 103 104 105 106 -0.5 -0.4 -0.3 -0.2 -0.1 0 Frequency (Hz) C'' / pF Freezing 24.1 oC 12 oC -5.7 oC -24.3 oC 101 102 103 104 105 106 -0.3 -0.2 -0.1 0 0.1 Frequency (Hz) C'' / pF 11 h 12 h 13 h 15 h 14 h 17 h 16 h 18 h 19 h Primary Drying TVIS APPLICATIONS HEAT TRANSFER COEFFICIENT (KV) DETERMINATION o The product temperature (TPRODUCT) derived by TVIS is one of the parameters needed for KV determination o Sublimation rate or drying rate (dm/dt) is estimated by TVIS 𝐾𝐾𝑉𝑉= 𝑑𝑑𝑚𝑚 𝑑𝑑𝑑𝑑× 2844 𝐽𝐽ȉ 𝑔𝑔−1 0.00045𝑚𝑚2 𝑇𝑇𝑆𝑆𝑆𝑆𝑆𝑆𝑆𝑆𝑆𝑆−𝑇𝑇𝑃𝑃𝑃𝑃𝑃𝑃𝑃𝑃𝑃𝑃𝑃𝑃𝑃𝑃 TPRODUCT and dm/dt from TVIS KV determination 0.00 0.02 0.04 0.06 0.08 0.10 10 12 14 16 18 20 Drying rate (g/h) Time /h RP determination 𝑅𝑅𝑝𝑝= 𝑃𝑃𝐼𝐼𝐼𝐼𝐼𝐼−𝑃𝑃𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶𝐶 𝑑𝑑𝑚𝑚 𝑑𝑑𝑑𝑑 ȉ 3.8 𝑐𝑐𝑐𝑐2 0 10 20 30 40 50 60 70 0 10 20 30 40 50 60 70 80 0 30 60 90 Heat radiation (% of total heat transfer) Over all heat transfer Coefficient (O.H.T.C) (w/m-2k-1) Pressure (Pa) O.H.T.C (water exp.) O.H.T.C (ice exp.) Heat radiation (water exp.) Heat radiation (ice exp.) Kv from TVIS dm/dt from TVIS Figure 2. KV values for 10 mL tubing vials (Brülls et al. 2002) Kv from TVIS = 37 Figure 3. The ratio of Rp and dry thickness as the function of dry thickness References 1. BRÜLLS, M. and RASMUSON, A. | poster |
Kontakt Dr. Andrea Beyer Institut für Klassische Philologie daidalos-projekt@hu-berlin.de Mastertitelformat bearbeiten Fachspezifische Methodenkompetenz Digital – Data – AI Literacy als Teil von Forschungskompetenz in der Klassischen Philologie User Story: Wie findet man, was nicht explizit im Text genannt wird? (DFG-Heisenberg-Projekt „Formen des ,Vergessens‘ in der römischen Literatur“, Prof. Dr. Verena Schulz, KU Eichstätt-Ingolstadt) Hintergrund: Geschichtsschreiber erwähnen bestimmte Ereignisse nicht, obwohl sie diese aufgrund ihrer Relevanz erwähnen sollten, bspw. kommt bei Cassius Dio die Konferenz von Luca 56 v. Chr. nicht vor, Cicero lässt bspw. Crassus weg. Konkrete Forschungsfrage: Gibt es eine kanonische Art (Ort, Personal, Thema), diese Konferenz zu erwähnen? Welche Kontexte sprechen für eine Erwähnung, welche dagegen? Fach- und fallspezifische Digital Literacies: − Digital Literacy: z. B. Datenformate (DOCX, TXT, HTML) verstehen, Lizenzrechte kennen, Ressourcen nachnutzen − Data Literacy: z. B. Daten zusammenstellen (Korpusauswahl), Korpussuchwerkzeug nutzen, Umgang mit Datenvisualisierungen − AI Literacy: z. B. Lemmatisierung und NER kennen, Vektorisierung von Tokens verstehen, Ergebnisse kritisch analysieren und Erklärungen für Ergebnisse finden (Basis: Fachkompetenz) Daidalos: Wie viel Methodenkompetenz braucht ein User? Humboldt-Universität zu Berlin Klassische Philologie, Korpuslinguistik, Computer- und Medienservice Andrea Beyer, Konstantin Schulz „Wie soll ich ein Forschungsvorhaben entwickeln, bei dem der Einsatz von NLP- Methoden sinnvoll wäre, wenn ich diese Methoden gar nicht kenne?“ Forschungskompetenz Verstehen Anwenden Bewerten Gestalten Digital Literacy Unterschied DOCX & TXT DOCX in TXT umwandeln Problemstellen in TXT identifizieren TXT fallspezifisch modifizieren Data Literacy Annotationen einordnen Annotationen interpretieren Fehlerhafte Annotationen reflektieren Annotationen in HTML verändern AI Literacy Konzept NER: mehrere Tagger pro Sprache NER-Ergebnisse vergleichen NER-Fehler systematisch auswerten NER-Tagger durch Feedback weiterentwickeln Fallspezifische Umsetzung eines Kompetenzstufenmodells mit Kompetenzdeskriptoren für die digitalen Teilkompetenzen von klassisch-philologischer Forschungskompetenz Texte Kritische Editionen Literatur Sprach- erwerb Über- setzungen Kom- mentare Kultur: Interdepen- denz, Modelle Literatur: Intertextua- lität, Wirkung Text: Autor, Genre Sprache: Stil, Klang Forschungsfelder der Klassischen Philologie Sprachen: Latein und Altgriechisch NER Sentiment Topics Embeddings … POS Preprocessing orange = Forscher oder Forscherin, blau = Daidalos 1. Kontaktaufnahme & Basisinfos, 2. Erstgespräch Forschungsfrage, 3. Forschungsmaterial, 4. NLP & Ergebnisse, 5. Zweitgespräch Ergebnisdiskussion, 6. ggf. Iteration 3-5, 7. Kooperative Publikation 1. 2. 3. 4. 1. 5. 4. 7. 6. Ablauf eines Forschungstandems Designentwurf der Daidalos-Benutzeroberfläche für NLP-gestützte Forschung: User spezifizieren ihre Forschungsfrage, wählen ein Textkorpus und planen dessen Verarbeitung. Forschen ohne Code Exemplarisches Jupyter-Notebook mit Programmiercode zur Implementierung von Lemmatisierung und Named Entity Recognition für altgriechische Literatur Forschen mit Code & Lernen anhand eines kuratierten Workflows Interaktive Übungen mit automatischem Feedback zum Kompetenzaufbau im Sinne der AI Literacy als Teil der angestrebten Digital Literacies, implementiert mit H5P Lernen zum Ausbau der Forschungskompetenz Workshops & Colloquia | poster |
Sensitivity of a middle atmosphere GCM to consistent scale-interaction of parameterized orographic gravity waves Benjamin Wolf, Erich Becker – Leibniz-Institut of Atmospheric Physics e.V. at Rostock University, email: wolf@iap-kborn.de Summary We find that the circulation in the middle atmosphere is significantly sensitive to the details of the OGW scheme. In particular, the vertical diffusion induced by saturation of OGWs has a considerable impact on the polar night jet during northern hemispheric winter, both by the diffusivity itself and by the secondary effect due to an upward shift of the breaking levels of NGWs. In turn, these changes affect the summer mesopause region by the interhemispheric coupling mechanism. A strong sensitivity of the mesosphere to GWs has also been found in the simulations of sudden stratospheric warmings (McLandress et al. [2012]). The damping of OGWs by boundary layer turbulence and the energy deposition by OGWs are found to be of minor importance. Model Description Difference to conventional parametrizations Classical OGW scheme and extensions Excitation with subgrid scale orographic perturbation field and resolved near-surface wind + Wave equations allow long vertical wavelengths Lindzen saturation hypothesis (Lindzen [1981]): convective instability leads to turbulent vertical heat and momentum diffusion of OGWs + Wave propagation according to WKB-Approximation: total turbulent vertical diffusion affects OGWs Momentum deposition, drag, by OGWs (OGWD) affects the resolved flow + Turbulent diffusion due to saturation of OGWs affects all other scales (resolved large-scale flow, NGWs) + Energy deposition by OGWs Zonal-mean model climatology from December to February (DJF). (a) Temperature (K, colors) and residual mass streamfunction (contours for -100, -10, -1, +0.001, +0.01, +0.1, +1, +10 +100 Mt s-1) . (b) Zonal wind (m s-1, colors) and complete Eliassen-Palm-Flux (EPF) divergence, including resolved waves and parameterized GWs (contours for -60, -40, -20, -10, -5, 5, 10, 20, 40, 60, 80 m s-1d-1) References M.J. Alexander et al., A Review of Recent Developments on Gravity Wave Effects in Climate Models and the Global Distribution of Gravity Wave Momentum Flux, Quarterly Journal of the Royal Meteorological Society, 2009 E. Becker and U. Burkhardt, Nonlinear Horizontal Diffusion for GCMs, Monthly Weather Review, 2007 E. Becker and C. McLandress, Consistent scale interaction of gravity waves in the Doppler-spread parameterization, Journal of the Atmospheric Sciences, 2009. R. Knöpfel and E. Becker, An idealized radiative transfer scheme for use in a mechanistic general circulation model from the surface up to the menopause region, Journal of Quantitative Spectroscopy Radiativ Transfer, 2011 H. Körnich and E. Becker, A simple model for the interhemispheric coupling of the middle atmosphere circulation, Advances in Space Research, 2010 R.S. Lindzen, Turbulence and Stress Owing to Gravity Wave and Tidal Breakdown; Journal of Geophysical Research, 1981 N.A. McFarlane, The Effect of Orographically Excited Gravity Wave Drag on the General Circulation of the Lower Stratosphere and Troposphere, Journal of the Atmospheric Sciences, 1987 C. McLandress et al., Dynamical control of the mesosphere by orographic and non-orographic gravity wave drag during extended northern winters of 2006 and 2009, Journal of the Atmospheric Sciences, 2012 General influence of parameterized orographic gravity waves Zonal-mean model climatology from December to February (DJF). (a) differences in the orographic wave drag, OGWD (m s-1d-1, colors) between the new and the conventional parametrisation and OGW- induced vertical diffusion coefficient in the control run (contours for 1, 4, 8, 15, 30 m-2s-1d-1) for DJF. (b) Differences in the complete Eliassen-Palm-Flux (EPF) divergence (m s-1d-1, colors) and complete EPF divergence in the control run (contours for - 60, -40, -20, -10, -5, 5, 10, 20, 40, 60, 80 m s-1d-1). OGW | poster |
European XFEL Data Analysis Workflows for SFX and beyond Oleksii Turkot, Fabio Dall’Antonia, Richard J. Bean, Juncheng E, Hans Fangohr, Danilo E. Ferreira de Lima, Sravya Kantamneni, Henry J. Kirkwood, Faisal H. M. Koua, Adrian P. Mancuso, Diogo V. M. Melo, Adam Round, Michael Schuh, Egor Sobolev, Thomas A. White*, Raphaël de Wijn, James J. Wrigley, and Luca Gelisio European X-ray Free Electron Laser, Schenefeld, Germany. European XFEL GmbH, Fabio Dall’Antonia, Holzkoppel 4, 22869 Schenefeld, Germany, Phone +49 40 8998-6411, fabio.dall.antonia@xfel.eu www.xfel.eu The SPB/SFX instrument [1] at the European XFEL (EuXFEL) provides a portfolio of experiment techniques for the structural elucidation of biomolecules, relevant to the life science domain - among those single particle imaging (SPI), small-angle X-ray scattering (SAXS) and serial femtosecond crystallography (SFX). All of these can exploit the MHz repetition rate of both the FEL accelerator and synchronised megapixel detectors in order to capture dynamic processes in the nanosecond time regime. Due to the ultra-short, ultra-brilliant laser pulses combined with rapid sample re-supply in e.g. liquid jets, SFX can be applied to micrometer-sized crystals, producing millions of almost damage-free single-shot diffraction images. Conclusions and Outlook References [1] A. Mancuso et al. (2019). J. Synchrotron Radiat. 26, 660. DOI: 10.1107/S1600577519003308 [2] T. A. White et al. (2012). J. Appl. Cryst. 45, 335. DOI: 10.1107/S0021889812002312 [3] O. Turkot et al. (2023). Crystals 13 (11). DOI: 10.3390/cryst13111533 [4] https://github.com/European-XFEL/DAMNIT Acknowledgements This work was partially supported by the consortium DAPHNE4NFDI in association with the German National Research Data Infrastructure (NFDI) e.V. NFDI is financed by the Federal Republic of Germany and the 16 federal states and the consortium is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) - project number 460248799. You are most welcome to contact the EuXFEL Data Analysis Group at da@xfel.eu. HALRIC Meeting 2024 Due to the peculiar pulse structure, a vast number of data sources and specifics of custom- built MHz pixel detectors, EuXFEL data are both large and complex. Accessible and reproducible data analysis workflows require software that can manage the complexity of data and provide low-barrier entry points for scientists. EXtra-Xwiz is a SFX-workflow-specific pipeline tool to interface CrystFEL with the preprocessing of EuXFEL data and distributed computing on HPC clusters. Other pipelines at EuXFEL, such as for X-ray photon correlation spectroscopy (XPCS), exist. DAMNIT follows a generic philosophy for data extraction from primary experiment sources as well as embedded processing software, and can be used for any experiment technique at EuXFEL, including SFX, SAXS and SPI. We are working on better support for the NeXus data standard, which will further enhance interoperability between software as well as between photon science facilities CrystFEL [2] is a widely used software suite that specialises on SFX data processing. EXtra-Xwiz [3] is a tool that manages data processing pipelines using CrystFEL, streamlining aspects such as the ingestion of EuXFEL-format data files and the scheduling of distributed computing on the HPC cluster. It can be integrated to the DAMNIT software [4] for metadata extraction and data analysis workflow management. B SFX at EuXFEL – i. p. the SFB/SFX upstream interaction region in vacuum – exploits a huge number of “shots” at the sample which is delivered in a jet. The X-ray probe exhibits a discontinuous 10 Hz train structure with MHz pulse repetition. The crystal hit rate is mostly below 10%. Peak finding and indexing with indexamajig (right, step 2) allows to distinguish between Bragg diffraction images and useless image frames. DAMNIT is driven by high level Python code and presents run-based primary metadata as well as processing results | poster |
Start Here: On Ramps for the VIVO Project Mike Conlon, mconlon@duraspace.org; Julia Trimmer, julia.trimmer@duke.edu; Graham Triggs, gtriggs@duraspace.org Project Managers Ask Questions Join bit.ly/vivo-community and ask away! Read the Implementation Guide VIVO has a guide to implementation. See bit.ly/vivo-planning Work with Data Providers Speak with data providers about VIVO and your project. Share your interest in research discovery, open scholarship, and linked data Join Outreach and Engagement Calls Monthly calls for sharing outreach and engagement experiences bit.ly/vivo-oaeig Help us Grow The VIVO Registry bit.ly/vivo- registry lists all VIVO sites. Add your site. Developers Install VIVO github.com/vivo-project Read the Documentation bit.ly/vivo-docs Ask Questions Join bit.ly/vivo-tech and ask away! Join Developer Calls See bit.ly/vivo-dig Develop Ontology Ontologies used by VIVO are developed using open source processes. See github.com/openrif Review/Open JIRA tickets See bit.ly/vivo-jira Become a Committer See bit.ly/vivo-committers Faculty Learn about VIVO The VIVO Book is available here: bit.ly/vivo-book Join All Group Get VIVO Updates, a weekly summary of the VIVO news. bit.ly/vivo-all Advocate for VIVO Talk to fellow faculty members and administrators about VIVO and the case for open scholarship, research discovery, and linked data Participate in your VIVO Work with your local VIVO project to generate value for faculty. Ask us about your local project. mconlon@duraspace.org gtriggs@duraspace.org Participate in the VIVO Project The VIVO wiki bit.ly/vivo-wiki has more info Members Consider membership Financial support for VIVO comes from VIVO membership in Duraspace. See vivoweb.org/membership Become a member Not a member? Becoming a member is simple. See bit.ly/dura-join Join All Group Get VIVO Updates, a weekly summary of the VIVO news. bit.ly/vivo-all Attend the Summit Premium members are invited to the Duraspace Summit held in Washington DC each March. See bit.ly/dura-summit Participate in Governance Serve on Leadership and/or Steering. See VIVO charter bit.ly/vivo-charter Service Providers Learn About Registered Service Provider (RSP) Program See bit.ly/dura-rsp Join All Group Get VIVO Updates, a weekly summary of the VIVO news. bit.ly/vivo-all Become an RSP Questions? Contact Jonathan Markow (jjmarkow@duraspace.org) Help us Grow The VIVO Registry bit.ly/vivo-registry lists all VIVO sites. Add your sites. Ask Questions We want to hear from you. Drop us a note mconlon@duraspace.org, gtriggs@duraspace.org Participate in the VIVO Project The VIVO wiki bit.ly/vivo-wiki has more info VIVO has many on-line resources. Here are some suggestions to help you get started. | poster |
Double-Active Membranes for a sustainable CO2 cycle DAM4CO₂ develops a novel membrane technology for the simultaneous CO₂ separation and its photocatalytic conversion to C4-C9 molecules, as renewable fuels. The project will deliver a prototype, designed using the design-build-test-learn approach, for a proof-of-concept validation that will be tested in lab-conditions. The DBTL approach is inherent in each scientific/technological WP of the project. Our objective: Partners: This project has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement No 101115488. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or European Innovation Council and SMEs Executive Agency (EISMEA). Neither the European Union nor the granting authority can be held responsible for them. WP1: Coordination & Management WP2: Materials Synthesis WP3: Materials Characterization WP4: Membrane preparation & Characterization WP5: Capture with Membranes WP6: Conversion with Membranes WP7: Multiscale Modelling & Life Cycle Assessment WP8: Dissemination & Communication & Exploitation WP9: Portfolio Activities Contacts PROJECT COORDINATOR Dr. Alessio Fuoco, CNR – ITM E-mail: alessio.fuoco@cnr.it Website: www.dam4co2.eu E-mail: dam4co2@itm.cnr.it Project number: 101115488 Project title: Double-Active Membranes for a sustainable CO2 cycle Project Acronym: DAM4CO2 Granting authority: EISMEA and UKRI Start date: 01/11/2023 Duration: 36 months EU Contribution: 2 975 275.00 € UK Contribution: 823 176.00 £ • Use of non-critical raw materials at any stage of the project • Greener material and protocols for membrane production • Development of the next generation membranes for CO2 capture using advanced polymers and MOFs • Development of photocatalytic membranes using mono and bi-functional catalysts for CO2 conversion into C4-C9 molecules • Integration of the CO2 management and valorisation processes into a single device • Design of novel membrane modules CNR (IT) INSTM (IT) ME-SEP (PL) UEdin (UK) PRIMALCHIT (ES) UPV-ITQ (ES) USwan (UK) DAM4CO₂, responding to the call "EIC Pathfinder Challenge: Carbon dioxide and nitrogen management and valorisation", aims at changing the existing paradigm within separation and utilization of CO₂ by coupling membrane and catalytic technologies. https://www.instagram.com/dam4co2/ https://www.linkedin.com/company/dam4co2 https://www.youtube.com/@DAM4CO2_EIC https://twitter.com/dam4co2 | poster |
Introduction • Radiation oncology physicists spend a lot of time performing and analysing pre- treatment patient-specific QA checks. Given this, we should ensure that our processes are fit for purpose. • Statistical control methods are suggested best practice for establishing, monitoring and retrospective review of QA processes and results1. These include histograms, control charts and control limits. • Our department used the installation of two new systems (the Varian Edge & Accuray Radixact) as an opportunity to reflect on and plan our future patient- specific QA processes, with control charts. Data SPC-derived control limit Modality points 2%/2mm 3%/2mm 3%/3mm VMAT (per beam) 61 93.3% 96.9% 99.1% VMAT (composite) 60 95.6% 98.4% 99.5% Tomotherapy 30 84.7% 96.0% 99.0% Radixact 35 98.1% 99.5% 99.8% Application of statistical process control methods in the retrospective review and design of patient-specific quality assurance processes Scott Crowe,1,2,3 Liting Yu,1,3 Samuel Peet,1,2,3 Tanya Kairn,1,2,3 1Royal Brisbane & Women’s Hospital; 2University of Queensland; 3Queensland University of Technology Conclusions • Control charts allow quantitative review of historical QA data and allow departments to determine tolerance limits specific to their planning, treatment and QA processes. This recommended by TG-2181 as best practice. • Consider how you record QA data and associated plan and dose information, to facilitate review, and in the future, potentially allow that data to be processed by machine- learning QA prediction tools. • Specificity and sensitivity testing in detection of simulated errors will be used to identify appropriate action limits. 90 92 94 96 98 100 0 10 20 30 40 50 60 2%/2mm gamma pass rate Quality assurance test case Individual control chart for VMAT QA results Background • Control charts are used to plot individual QA data points or differences between consecutive data (MR, moving range). • Control limits can be calculated from the QA data: Control limit = തx −2.66 MR • Typically calculated for a build phase, e.g., initial 30 results. • Control limits are tolerance limits and describe expected system performance. QA results beyond limits are assumed to have an assignable cause. Tolerances are distinct from action limits, which are defined by potential clinical impact. References 1.Miften M, et al. Med Phys. 2018;45:53–83. 10.1002/mp.12810 Disclosures The authors have nothing to disclose. The study was exempted from ethical review (EX/2021/QRBW/82062). scott.crowe@health.qld.gov.au Poster presented at EPSM 2022. Questions? Ask me! Calculated limit of 95.6% Out of control QA results Average result of 99.1% Methods Results • Build phase data was not entirely in control for some data, suggesting that there are assignable causes for QA failure. • For simplicity and conformity between modalities, tolerance limits of 95% (and action level of 90%) using 2%/2mm gamma criteria were preferred by the physics team for future VMAT composite and Radixact QA evaluations. • Process performance metrics indicate that our planning, dose calculation, delivery and QA processes should reliably produce plans that are able to meet these tolerance limits. Octavius 1500 data collected for 30+ VMAT, Tomo & Radixact plans. Pass rates calculated for multiple sets of gamma criteria pairs. Charts, limits, and process performance characterised for calculated data. Results and plans for ongoing QA discussed in physics team meeting. | poster |
IN VITRO REGENERATION PROTOCOLS FROM IMMATURE MALE FLOWER BUDS OF BANANA CV. KARPURA CHAKKARAKELI (AAB) AND ASSESSMENT OF GENETIC FIDELITY WITH SSR & ISSR MARKERS M. Viswanath 1* B. V. K. Bhagavan2 K. Ravindra Kumar3 P. Subbaramamma4 M. GirijaRani5 *1 Ph.D Scholar, Department of Fruit Science, College of Horticulture, V.R. Gudem, 2 Principal scientist & Head, 3Scientist, 4Associate professor, 5Senior Scientist & Head Dr. Y.S.R. Horticultural University, Venkataramannagudem – 534101, Andhra Pradesh, India. *Corresponding author’s email:viswahorti123@gmail.com An efficient in vitro propagation protocol has been developed for the first time on direct differentiation of shoot buds from immature male flower buds of banana cv. Karpura Chakkarakeli (AAB). MS media supplemented with 1.0 mgL-1 TDZ + 0.5 mgL-1 IAA + 2 mgL-1 CH was found optimal for per -cent cauliflower-like bodies (CLBs) formation (75.04%), maximum number of CLBs (15.01) explant-1 and minimum number of days (43.54d) taken for CLBs induction. The highest per cent (75.37%) and maximum number (12.78) of shoots proliferated explant-1 within 120 days after culture initiation. The regenerated plantlets rooted better in half MS media supplemented with 0.5 mgL-1 IBA and hardened with 97% survival rate. SSR & ISSR markers were employed to assess the genetic stability of in vitro regenerated and multiplied plantlets of banana cv. Karpura Chakkarakeli (AAB) recorded 100% monomorphic across all the regenerated plants with the mother plant. Plate 1. Different stages of in vitro regeneration in banana cv. Karpura Chakkarakeli (AAB). a Mother plant bearing fruits and male flower bud. b Excised male flower bud. c Reduced male floral bud (6-7cm). d A group of male flowers (hands) used for culture. e Floral explants initiated on MS basal medium supplemented with 1 mgL-1 TDZ + 0.5 mgL-1 IAA + 2 CH. f Clusters of Cauliflower-like-bodies (CLBs). g CLBs converting to shoots. h In vitro shoot clusters i Plantlets ready for hardening. Secondary hardened plantlets. . ur s Plate 2. Morphogenic responses from the immature male flower explants of banana cv Karpura Chakkarakeli (AAB) in T14 treatment A. Responded explant (7 DAI) B. Green colo swollen base (15 DAI) C. Perianth necrosis (20 DAI) D. Formation of Cauliflower-like-bodie (CLBs) (30 DAI) E. Formation of shoot buds (60 DAI) F. Shoot clusters(90 DAI). Murashige and Skoog’s (MS) media supplemented with 1.0 mgL-1 TDZ + 0.5 mgL-1 IAA + 2 mgL-1 casein hydrolysate was found optimal for per cent cauliflower- like bodies (CLBs) formation (75.04%), maximum number of CLBs (15.01) explant-1 and minimum number of days (43.54d) taken for CLBs induction. The highest per cent (75.37%) and maximum number (12.78) of shoots proliferated explant-1 within 120 days after culture initiation.The regenerated plantlets rooted better in half MS media supplemented with 0.5 mgL-1 IBA and hardened with 97% survival rate. SSR & ISSR amplified products were 100% monomorphic across all the regenerated plants and mother plant. RESULTS & DISCUSSION MS media supplemented with 1.0 mgL-1 TDZ + 0.5 mgL-1 IAA + 2 mgL-1 CH in 0.25% gel-rite was found optimum for mass production of this commercially important banana cv. Karpura Chakkarakeli (AAB) from IMF buds. CONCLUSION Amplification with SSR & ISSR primers A) Ma-SSR-230 B) UBC 868 300 bp B ABSTRACT INTRODUCTION Karpura Chakkarakeli (AAB), the choicest table cultivar of banana belongs to Mysore subgroup commercially grown in the coastal districts of Andhra Pradesh. Due to its highly recalcitrant nature, excessive phenol compounds, biotic contamination and poor multiplication rate causing the major hindrances for its commercial multiplication through shoot tip explants. Keeping in this view, this study was aimed to examine the potential of male flower explants as an alternate source material for culture establishment, morphogenetic responses and direct organogenesis with different combinations and concentrations of plant | poster |
support IL layer metal particle/center Improved electrochemical perfor- mance of Fe-N-C catalysts through ionic liquid modification in alkaline media Thomas Wolker, Ioanna Martinaiou, Ali Shahraei, Gui-Rong Zhang, A. Janßen, Stephan Wagner, Natascha Weidler, Robert W. Stark, Bastian J.M. Etzold*, Ulrike I. Kramm Electrochemistry 2018, 24.-26.09.2018, Ulm correspondence: Prof. Dr.-Ing. B.J.M. Etzold email: etzold@tu-darmstadt.de Ernst-Berl-Institut phone: +49 (0) 6151 / 16-29984 Alarich-Weiss-Str. 8 fax: +49 (0) 6151 / 16-29982 D-64287 Darmstadt http: www.etzoldlab.de literature: [1] Y. Nie, L. Li, Z. Wei, Chem. Soc. Rev. 44 (2015) [2] G.R. Zhang, M. Munoz, B.J.M. Etzold, ACS Appl. Mater. Interfaces 7 (2015) [3] G.R. Zhang, M. Munoz, B.J.M. Etzold, Angew. Chem. Int. Ed. 55 (2016) [4] I. Martinaiou, T. Wolker, B.J.M. Etzold, et al., J. Power Sources 375 (2018) Highly active oxygen reduction reaction (ORR) electrocatalysts that are stable under operating conditions are needed in order to enable a widespread commercialization of the fuel cell technology. State-of-the-art ORR catalysts are mostly based on platinum. Due to their high price noble-metal-free alternatives are highly desirable [1]. Carbon-based materials emerge as one of the promising candidates due to their remarkable advantages of low cost, abundant structural variety, tailorable surface chemistry, and good conductivity. Transition metal-nitrogen-carbon catalysts (e.g. Fe-N-C) are considered as one of the most promising representatives of this catalyst class. However, these systems often show a poor stability during electrochemical cycling and therefore still need to be improved in order to replace state-of-the- art noble metal catalysts. Quite recently we have demonstrated that filling the pores of Pt/C catalysts by a minor amount of Ionic Liquid ([BMIM][NTf2], [MTBD][NTf2]) would significantly boost the catalytic activity of Pt/C for ORR [2,3]. This was explained by the fact that the modification led to a new microenvironment around active centers that would prevent the poisoning with oxygenated species. Inspired by this work, herein we transfer this strategy to the Fe-N-C catalysts [4]. § Fe-N-C catalysts with and without sulfur were prepared § Sulfur addition led to a slightly increased micropore volume § Modification of sulfur free catalysts with [BMMIM][NTf2] increased the catalytic ORR- activity in a similar range as sulfur addition § The different behavior of the sulfur containing catalyst could be explained by pore blocking effects § IL modification could thus be an interesting way to obtain highly active and stable noble- metal free electrocatalysts for fuel cell aplications Introduction Oxygen Reduction Reaction Solid Catalysts with Ionic Liquid Layer (SCILL concept) α = 0 α = 10% α: pore filling degree α = VIL/Vpore,0 The pores of a catalyst are partially filled with Ionic Liquid to create a new microenvironment around active centers Highly active catalyst needed to overcome sluggish kinetics Selectivity towards 4 e- - pathway desired Conclusions O2 OH- HO2- O2 OH- HO2- 2e- 2e- 4e- O2 H2O H2O2 2e- 2e- 4e- Alkaline Acidic Dicyandiamide Iron acetate Phenanthroline Thermal decomposition 800 °C Acid leaching 2nd heat treatment Fe-(S)-N-C Sulfur ( ) ( ) Catalyst Synthesis and Modification Fe-(S)-N-C-SCILL Unreactive species Textural Characterization SBET /m2 g-1 SMicropore /m2 g-1 SMesopore /m2 g-1 VPore /cm3 g-1 -S 416 218 201 0.49 +S 442 299 165 0.44 Nitrogen sorption revealed similar textural properties Electrocatalytic Performance IL Modification can cause similar boosting as sulfur Stability can also be improved by IL addition [BMMIM][NTf2] TW, GRZ and BE acknowledge funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement n° 681719) Acknowledgment + IL | poster |
CO-CREATING EXERGAMES WITH PARKINSON’S DISEASE PATIENTS T. Savvidis*, E. Konstantinidis*, S. Dias**, V. Zilidou*, E. Romanopoulou*, L. Hadjileontiadis***, P. Bamidis* *Lab of Medical Physics, School of Health Sciences, Aristotle University of Thessaloniki **Faculdade de Motricidade Humana Universidade de Lisboa Lisbon, Portugal ***Faculty of Technology, Aristotle University of Thessaloniki teo.savvidi@gmail.com, evdokimosk@gmail.com, sbalula@fmh.ulisboa.pt, vickyzilidou@gmail.com, evangeliaromanopoulou@gmail.com, leontios@auth.gr, pdbamidis@gmail.com Introduction In this study, the Minimum Viable Product (MVP) model was applied with regards to “Measure-develop- learn” circle along with its impact on the decision for the development tools and technologies. An example of designing exergames for Parkinson’s disease (PD) patients by considering their valuable feedback [1] and how this influenced low-level technical decisions (changing game engine from 2D Exergames to 3D) are thoroughly discussed. PD Patients feedback Develop Learn/Design Methodology The designing procedure inluded the ivolvement of PD patients in a discussion in which a draft version of the games was presented through storyboards (Figure 1) [1] and followed by a questionnaire. The feedback collected through this process led the developers to design the first game in 2D as part of the wFitForAll web based platform [2][3]. The first 2D prototype game (Figure 2) was presented to the PD patients in an open discussion and a questionnaire has been utilised for the feedback acquisition. The most remarkable point was that although in the design thinking phase the PD patients had reported that they would prefer 2D simple graphics, they were not so enthusiastic but prefered more realistic 3D games. Results The results from the first MVP circle showed that 7/10 patients asked about storyboards/2D would like the abstract/animated design. The second MVP circle leaded to the creation of the Unity 3D prototype. The third MVP circle showed that 3/4 patients asked about the 3D prototype, they liked it more from the 2D. The evaluation process of the second 3D prototype lead us to create more games, 14 in total. Conclusion Using the MVP circles in a spiral way helped us to understand the needs of the PD patients regarding the exergames and develop them more efficiently. The 14 games will be evaluated again in the future during the pilot tests. References 1.S. B. Dias, E. Konstantinidis, J. A. Diniz, P. Bamidis et al., On supporting Parkinson's Disease patients: The i-PROGNOSIS Personalized Game Suite design approach. Computer-Based Medical Systems - IEEE CBMS, Thessaloniki Greece, 2017 2.WebFitForAll platform (www.fitforall.gr). 3.Konstantinidis E, Bamparopoulos G and Bamidis P. Moving Real Exergaming Engines on the Web: The webFitForAll case study in an active and healthy ageing living lab environment, IEEE Journal of Biomedical and Health Informatics, 2016 Acknowledgement The work has been partially supported by the EU H2020-PHC21-2015 ‘i-PROGNOSIS’ Project (N° 690494), as well as, the LLM Care (www.llmcare.gr) self-funded initiative that emerged as the business exploitation of the Long Lasting Memories Project originally funded by the ICT-CIP-PSP programme. We thank Parkinson’s disease association (Thessaloniki, Greece) for their support and their contribution on this study. Figure 1. Storyboard Using the Unity3D, the game was re-developed in 3D with realistic graphics and physics in high resolution (Figure 3) . The realistic physics and the high resolution graphics couldn’t be supported by the Android depth sensor, while the “Low Poly” design adopted, which offers faster rendering because of the small amount of polygons of the model. The final 3D prototype (Figure 4) developed following this new and modern style and improves the Frame per second (FPS) and the gameplay. Figure 2. 2D Prototype Figure 3. First 3D Realistic Graphics Figure 4. Final 3D Design Figure 5. Three out of f | poster |
ORIENTACIÓN Y DECORACIONES ASTRONÓMICAS DE HÓRREOS DEL SUR DE GALICIA Las poblaciones de Beade y Vilaboa Cintia Cabada (1,2), Marta González (1,3), Ana Ulla-Miguel (1,2), Fátima Braña (1), Esther Pérez (1,4), Beatriz Martínez (1,5) 1: Grupo de Astronomía, Astrofísica, Antropología Cultura y Educación (A3CE - Universidade de Vigo), 2: Centro de Investigación Mariña (CIM – GEOMA, Universidade de Vigo), 3: Universidad Internacional Valenciana, 4: IES de Beade, Vigo 5: CPI O Toural de Vilaboa e-mail: marta.gonzalezg@professor.universidadviu.com 5- AGRADECIMIENTOS: Un especial agradecimiento al alumnado colaborador del colegio CIP O Toural de Vilaboa y el instituto IES Beade de Vigo. También agradecemos el apoyo del Servicio Público de Empleo Estatal (SEPE) y de la Universidad de Vigo, bajo el contrato E-36-2023-0072917 1- RESUMEN: Los hórreos son construcciones elevadas para conservar el grano características del Norte de España. Actualmente, su interés trasciende su objetivo original y están considerados bienes de interés cultural en Galicia. Esto ha supuesto su protección e inclusión en catálogos oficiales, lo que permite recabar información para su estudio. Por desgracia, los catálogos están dispersos en diferentes entidades, y presentan formatos que dificultan un tratamiento automatizado y robusto de los datos. Este trabajo extiende estudios etnoastronómicos previos de dos parroquias del Concello de Vilaboa. Se presentan muestras consistentes, obtenidas in situ y enfocadas a la decoración astronómica, en las parroquias de Vilaboa y Beade, además de una muestra limpia y homogénea de más de 200 hórreos en la parroquia de Beade procedente del catálogo del Concello de Vigo. En ambas poblaciones, podemos encontrar hórreos que presentan decoración astronómica tanto en adornos sobre el tejado (relojes de sol) como tallados en las paredes de piedra (lunas y estrellas). Por ello, además de caracterizar los datos, se comparan ambas poblaciones desde la perspectiva de la astronomía cultural. 3- METODOLOGIA: 2- OBJETIVOS: ❖Actualizar el registro de los hórreos en dos ubicaciones diferentes (ayuntamiento Vilaboa y parroquia Beade, Vigo). ❖Comparar caracteres cuantitativos y cualitativos entre ambas poblaciones con un enfoque etnoastronómico. ❖Buscar si existe alguna relación entre alguno de los caracteres (principalmente el azimut) y la presencia de decoración con motivos astronómicos. Figura 2 - Hórreos del ayuntamiento de Vilaboa: a- Hórreo de piedra con una estrella de cinco puntas tallada. b- Decoración tallada en piedra de dos rosas hexapétalas. c- Estrella decorativa de cuatro puntas. d- Hórreo de piedra con 3 estrellas de cuatro puntas talladas y un “respiradero” en forma de media luna. Figura 4 - Histogramas de azimut, medidos entre 0 y 180 grados: a- Ayuntamiento de Vilaboa b- Parroquia de Beade Figura 6 - Diagramas sectoriales para los caracteres cualitativos estudiados: a- Parroquia de Beade. b- Ayuntamiento de Vilaboa. 4- CONCLUSIONES: ❖Este estudio ha permitido crear una base de datos de los hórreos en las poblaciones estudiadas y el registro de sus ubicaciones en mapas. ❖La prueba de Kolmogorov-Smirnov (a un 5% de significación) no rechaza la hipótesis nula de que ambas muestras provengan de la misma distribución de azimuts o anchos, pero sí en longitudes. ❖La pequeña concentración en longitudes bajas en la muestra de Beade no está presente en la de Vilaboa, donde ambas dimensiones muestran distribuciones más uniformes. ❖La mayoría (~3/4) de los hórreos en Beade están compuestos de materiales mixtos, mientras que la mayoría (>50%) de los hórreos en Vilaboa están hechos de piedra. ❖La mayoría de las muestras en Vilaboa muestran decoraciones en las paredes, en comparación con ~15% en Beade. En ambos casos, la mayoría tiene motivos astronómicos. Si incluimos relojes de sol, casi un tercio de los hórreos de Beade tienen un elemento astronómico. ❖El uso actual de los hórreos puede haberse visto alterado desde la fecha de recogida | poster |
Introduction Discussion Selected references Rayner (1998). Psych Bull, 124(3), 372–422. Vitu (2011). In : The Oxford handbook of eye movements (pp. 731–749). Rayner (1979). Perception, 8(1), 21–30. McConkie et al. (1989). Percept Psychophys, 46(3), 245– 253. Vitu et al. (2001). Vis Res, 41(25-26), 3513–3531. Henderson (1993). Can J Exp Psychol, 47(1), 79-98. van der Linden et al. (2015). J Vis, 15(5), 1–18. van der Linden et al. (2015). Att Percept Psychophys, 1– 16. Nazir et al., (1991). Bull Psychon Soc, 29(2), 171–174. Nuthmann et al. (2007). Vis Res, 47(7), 990–1002. Vitu et al. (1995). Percept Psychophys, 57(3), 352–364. Adeli et al., (2015), VSS. [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] Away from center Away from center Away from center Away from center 3° 5° PVL effects Away from center Away from center versus PVL OVP I-OVP PVL OVP I-OVP Real objects Meaningless non-objects Methods + 3° + + + + Stimulus type (between blocks) Eccentricity (within blocks) 3° 5° 5° Manipulations Real objects Stimuli Non-objects Hemera objects Width 0.85-2.10° Normalized on px Texture synthesis Width constant 0.85° Normalized on px + Task Saccade towards the object as fast as possible Landing positions Normalized x coordinates -0.5 0 0.5 on-object off-object off-object -1 1 Laboratoire de Psychologie Cognitive Lotje van der Linden1, Gregory J. Zelinsky2 and Françoise Vitu1 Aix Marseille université cnrs l.vanderlinden@cogsci.nl www.cogsci.nl/lvanderlinden 1. Aix Marseille Université, CNRS, Laboratoire de Psychologie Cognitive UMR 7290, Marseille, France 2. Department of Psychology, Stony Brook University, New York, United States Viewing-position effects in meaningless object viewing PVL OVP vêtements vêtements vêtements I-OVP Frequency Refixation probability Initial-fixation duration Eye movements during object viewing → same regularities [6-8] The center of a stimulus is optimal for visual extraction [9] 20° 10° 0° 10° 20° 40° 60° 0.0 0.2 0.4 0.6 0.8 1.0 Fovea Relative visual acuity vêtements Degrees from fovea Eye movements during reading → regularities [1, 2] Eyes land near the center of words → preferred viewing location (PVL) effect [3] Central landing positions result in less refixations → optimal viewing position (OVP) effect [4] and longer initial fixation durations → inverted OVP (I-OVP) effect[5] We know that... Several nocturnal animals were observed. Normal condition Zzzzzzz zzzzzzzzz zzzzzzz zzzz zzzzzzzz. Z-reading condition versus Differences → cognitive processing Similarities → visuomotor processing Real objects Meaningless non-objects versus Are PVL, OVP and I-OVP effects Directly caused by these visual-processing advantages? e.g. PVL = strategy to aim at center to optimize visual-information uptake All effects generalize to mindless reading e.g. 10, 11] Is the same true for mindless object viewing? Or are they visuomotor processes? e.g. PVL = automatic center-of-gravity effect Research question: Regularities during reading reflect visuomotor constraints PVL, OVP and I-OVP generalized → The eyes prefer to land at, and stay at, the center of stimuli We found that... regardless of stimulus content This suggests that... PVL, OVP and I-OVP effects reflect low-level visuomotor processing and not higher-level ongoing processing such as object recognition This is important for... models on eye guidance in scenes increased predictive power whenimplementing visuomotor constraints [12] Results | poster |
GND in a Nutshell Ein Normdatensatz beschreibt regel- basiert eine bestimmte Entität. Die Datensätze enthalten Informationen, die die entsprechende Entitäten ex- plizit charakterisieren und so identifizieren. Die Gemeinsame Normdatei (GND) ist ein Dienst, um Normdaten kooperativ nutzen und verwalten zu können. Diese Normdaten reprä- sentieren und beschreiben Entitäten, wie Personen, Körperschaften, Kon- ferenzen, Geografika, Sachbegriffe und Werke, die in Bezug zu Kulturgut sowie kulturellen und wissenschaft- lichen Sammlungen stehen. Anforderungen sammeln Auf der Grundlage vorliegender Erfahrungen aus der Text+ Community, die zum Beispiel über die zahlreich eingereichten User Stories gesammelt wurden, werden Bedarfe an eine GND- Agentur ermittelt. Diese Aufgabe führen wir im Rahmen verschiedener Formate wie dem GND-Forum weiter, wobei ein Ergebnisbericht zum Dezember 2023 vorliegen wird. In Case Studies überführen Die ermittelten Bedarfe werden in Case Studies überführt. In der Datendomäne Editions schauen wir anhand von drei Editions- projekten an der SUB Göttingen, wie die Bedarfe an GND-Norm- datensätzen in konkreten Work- flows umgesetzt werden können. Ähnlich werden wir für die Datendomänen Collections und Lexical Resources verfahren. Die Workflows aus den Case Studies sollen in allgemeine, skalierbare Workflows bis April 2024 übertragen werden. Prototypische Strukturen testen Wir möchten die bereits vorhandenen und in Planung befindlichen Strukturen testen. Damit wollen wir gewährleisten, dass die technischen, administrativen und daten- theoretischen Strukturen der Agentur für die Text+ Community adäquat sind. Die Produktivnahme ist zum Juni 2025 geplant. Das NFDI-Konsortium Text+ wird gefördert durch die Deutsche Forschungsgemeinschaft (DFG) unter der Projektnummer 460033370. Text+ ist Teil der Hintergrund: „Frankfurt am Main“ im GND-Explorer. DNB 2022. CC BY-SA 3.0 Icon Nutshell: Tatyana. Noun Project. Icon Road: Sergey Krivoy. Noun Project. beide CC BY 3.0 https://gnd.network/Webs/gnd/DE/UeberGND/FAQ/faq_node.html Agenturaufgabenbaum. Jürgen Kett, DNB, Mai 2022. CC BY-SA 3.0 Task Area Infrastructure/Operations Ein Baum in der Roadmap Kontakt: gnd-info@dnb.de Poster: „Ein Baum in der GND – Gemeinsame Normdatei“ Inhalt: Text+ Infrastructure/Operations Verantwortlich: Marie Annisius , Barbara Fischer , Alexander Steckel Event: Text+ Plenary, 12-13. September 2022, Mannheim | poster |
An Exploration of <object> using Antarctic Artifacts Suzanne Raybuck and Sarah Stanley Problem The recent inclusion of <object> to the TEI has been a long-awaited addition to the language that was adapted from the msdescription module. With this project, we set out to test the effectiveness of the <physDesc> element within <object> and the effectiveness of the current concept of describing general objects. Methodology To test the effectiveness of <physDesc>, we selected six objects from FSU Special Collections. These objects demonstrated a variety of physical characteristics we wanted to capture. We then described these objects in as much detail as possible through observation then took the resulting document and converted it into descriptive markup in the TEI. While marking up our descriptions, we paid special attention to which current child elements of <physDesc> were applicable to the object. We also tested how the current content model restricts accurate description and markup. Based on this markup we then created an ODD file to add elements that would address the observations and questions we had while initially describing the objects. Result and Discussion We produced six descriptions of our objects to test the utility of <physDesc> and its child elements <objectDesc>, <decoDesc>, and <typeDesc>. Each object presented a different challenge to describe and resulted in a number of questions about the current version of <physDesc>, such as: • What is the difference between <physDesc> and <objectDesc> when describing objects and not manuscripts? • Are the current child elements from the msdescription module still applicable to general objects? • How do we subdivide objects into parts that can be described within <physDesc>? Based on our observations, we decided to create two models for segmenting objects for description: one that was meant to segment the descriptions themselves, and another that segmented the objects and linked these segments to their descriptions. Figure 7. Model of a United States Navy Icebreaker. Figure 3. U.S. Naval Mobile Construction Battalion Plaque. Figure 1. Ceramic Penguin Figurine. Customization #1 – <objectSector> • Creates an <objectSector> element within <object> which lays out segments of the object • Assigns an @xml:id for linking to corresponding prose in <objectDesc> • Considers the segmentation of the object information about the object itself Figure 5. Navy Icebreaker description using <sectorDesc>. Customization #2 - <sectorDesc> • Creates a <sectorDesc> within <objectDesc> element • Provides the user a way of being more precise by segmenting the description of the object • Considers segmentation a feature of the description, rather than the object Both Customizations • Created subdivisions of objects for more nuanced description • Allow for the use of @place to segment the objects • Utilize custom att.3Dcoordinates which allows the user to define a box-like space that encloses the area being described. Ideally these coordinates will map onto some 3D model of the object Figure 4. Navy Icebreaker description using <objectSector>. Figure 6. Schema for our att.3dcoordinates attribute class. View all our files for this project in our GitHub repository at https://github.com/sraybuck/AntarcticObject Figure 2. Emergency Lantern. | poster |
libEnsemble: New capabilities for coordinating dynamic ensembles of calculations Stephen Hudson Jeffrey Larson John-Luke Navarro Stefan M. Wild Overview libEnsemble is a Python toolkit for coordinating dynamic, asynchronous ensembles of calculations on massively parallel resources. Worker processes launch simulation and generator functions. libEnsem- ble also provides: • Ad-hoc task generation • Dynamic Resource management • Application monitoring • Portability and flexibility • Coordinating data-flow between tasks • Low startup cost: pip install libensemble • Configure via Python scripts or yaml/toml/json Cross-System Ensembles libEnsemble can submit remote apps and user functions via the Balsam and funcX platforms. With Balsam: Remote applications With funcX: Remote simulation functions Multifidelity optimization of a WarpX laser-plasma simulation Multi-fidelity simulations have demon- strated 10x speedup over single fidelity equivalents. Progress from ten replications of libEnsem- ble+WarpX with two multifidelity meth- ods and a single (highest) fidelity method. Objective value is computed from the highest fidelity simulation. Variable Resource Management libEnsemble’s Resource Manager now divides resources into resource sets that can be assigned (and dynamically reas- signed) to workers. This enables easy support of multi-fidelity simulations. Community Examples and Integrations The libEnsemble repository includes many simple exam- ple functions. Users can also now contribute to a separate growing library of functions and complete workflows, encouraging maximum code re-use. Example genera- tors include optimization, calibration, machine learn- ing, and many others. Libensemble/libe-community-examples All Workflows are Portable • Summit • Polaris • ThetaGPU • Perlmutter A New Pythonic Interface Download or Contribute Available through pip: pip install libensemble conda through conda-forge channel: conda install -c conda-forge libensemble Spack: spack install py-libensemble GitHub: http://github.com/Libensemble/libensemble Read the Docs: https://libensemble.readthedocs.io | poster |
Primary cilium remodelling mediates a cell signalling switch in differentiating neurons Gabriela Toro-Tapia1 and Raman M. Das1. 1Division of Molecular and Cellular Function, Faculty of Biology Medicine and Health, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK. INTRODUCTION • Neurons are amongst the most highly polarised cell types [1,2]. • Cells undergoing neuronal differentiation shed their apical membrane via the regulated process of apical abscission [3], leading to acute loss of cell polarity and delamination from the neuroepithelium (A,B). • Apical abscission also results in disassembly of the apical primary cilium, leading to curtailment of Shh signalling and onset of cell cycle exit (C). • Newborn neurons repolarise in response to extracellular signals, leading to extension of a nascent axon in the correct orientation. Figure 1: A) Cartoon represents a two-day-old chick embryo. The transverse section of the spinal cord shows the apicobasal polarity of neural progenitors and the sequence of events leading to neuronal differentiation. B) The primary cilium and centrosome are located at the apical pole of cells in the early stages of neuronal differentiation. C) Apical abscission leads to acute loss of apical polarity and primary cilium dis-assembly. B C RESULTS CONCLUSIONS References: [1] Takano, T., et al. (2015). "Neuronal polarization." Development 142(12): 2088-2093;[2] Barnes, A. P. and F. Polleux (2009). "Establishment of axon-dendrite polarity in developing neurons." Annu Rev Neurosci 32: 347-381;[3] Das, R. M. and K. G. Storey (2014). "Apical abscission alters cell polarity and dismantles the primary cilium during neurogenesis." Science 343(6167): 200-204. A I) The primary cilium is dynamically disassembled and remodelled during neuronal differentiation II) Intraflagellar trafficking is inactive in the Arl13b+ particle and reactivated during apical process retraction • Cells delaminating from the neuroepithelium undergo primary cilium dis-assembly and inherit a small Arl13b+ particle, leading to acute cessation of canonical Shh signalling. • Arl13b+ particle elongates and progressively initiates intraflagellar trafficking (IFT) as it transits towards the cell body, indicating primary cilium remodelling. • Ciliary accumulation of the Shh transducer Smoothened (Smo) is gradually restored during cilium remodelling in the absence of Gli transcriptional activity. • The remodelled primary cilium directs neuron polarisation and subsequent axonogenesis via a non-canonical Shh signalling. • This work indicates that cilium remodelling provides differentiating neurons the opportunity to configure a new signalling centre to facilitate a qualitatively different response to the common signalling environment. Apical process { Figure 2:. A) Time-lapse sequence showing Arl13b+ particle retention following apical abscission. White arrow indicates apical abscission, white arrowhead the retained Arl13b+ particle and yellow arrowhead the abscised primary cilium. Dashed magenta lines indicate ventricular surface. Scale bar: 10µm. Boxed regions are enlarged in right-hand panels. Primary cilium is highlighted by dashed white lines. Scale bar: 0.7µm. B) Time-lapse sequence of a cell undergoing primary cilium reassembly during apical process retraction. Dashed cyan lines demarcate cell body of differentiating neuron and white arrowhead the reassembling primary cilium. Boxed regions are enlarged in right-hand panels. Scale bar: 5µm and 0.7µm (enlarged region). C) Cell undergoing axonogenesis transfected with Arl13b-GFP to label the ciliary membrane (green), mKate2-GPI to label cell membrane (red), and Ngn2-GFP (green), Scale bar: 5µm. D) Representation of differentiating neurons at different stages of apical process retraction and early stages of axonogenesis. E) Immunostaining to detect Tuj1+ cells (green) and endogenous Arl13b (red) at different stages of apical process retraction. Scale bar: 5µm an | poster |
System Development for Potato Crop Growth Management Tao Zheng, Meng Cheng, Hong Sun *, Minzan Li, Wei Yang, Lihua Zheng, Man Zhang Key Laboratory of Modern Precision Agriculture System Integration Research Ministry of Education Key Laboratory of Modern Precision Agriculture System Integration Research, Ministry of Education, China Agricultural University, Beijing 100083, China. sunhong@cau.edu.cn A large number of data on the growth of potato crops and environmental parameters were collected through the sensor during the growth of the potato crop. In order to improve management efficiency and provide production decisions, a system for potato crop growth management was developed. The system can store, retrieve, manage and make decision on potato crop growth, and provide guidance for real-time monitoring and optimization of crop growth process. The system is a convenient, fast, efficient and low-cost agricultural management system. Introduction The system selected the current mainstream J2EE architecture, SSH framework, the database using MySQL, and the application of Eclipse for system development, forming a clear framework to improve the reusability of t Methods Non-destructive detection of chlorophyll content of potato crop leaves can indicate crop growth and guide field management. The hyper-spectral images of 65 potato leaves were collected and divided into 400 regions of interesting (ROI) Meanwhile the SPAD values of these 400 ROI Experiment and Discussion , g g y Fig. 1 SSH framework components. (ROI). Meanwhile, the SPAD values of these 400 ROI samples were measured. All of the data mentioned above could be managed by the system. After long-term operation, the software system ran normally. Moreover, the data could achieve the correct load and output. In the future, the system could be optimised and used to connect with the farmland information collection device. Wh th t i th fi ld Th i d t Th t i di id d i t f d l i f ti When the sensors were set up in the field. The sensing data could be collected data every 5 minutes and sent it to the server. The software system then retrieved the data from the server for management and subsequent processing. The system is divided into four modules information platform and auxiliary functions. i. Common operation module related to the management for farmland data and user data. ii. System management module viewed the data collected in the experiment and spectral data analysis results. iii. Information platform module mainly aimed at the function of agriculture warning. iv. Auxiliary functions module had a very strong expansibility, and viewed the mapping analysis and so on. Fig. 3 The system operating result The system reduced a large number of system requirements analysis and system development costs, and provided Fig. 2 The structure of software system effective information support for special users with specific needs. The system makes it easy for people to search and query information about growing potato crops. 1. The system considered the optimal allocation of environmental resources, cultivated land resources, Conclusions and Acknowledgements varieties and chemical fertilizers, such as light and warm water produced by potato crop. 2. The system realized the data synchronization between the server and the browser. Users could make real- time use of information to make timely agricultural decision-making. 3. This study was supported by Research on Rapid Diagnosis Method and Mechanism of Nitrogen Nutrition of Dry-planted Potato Crops Supported by the National Natural Science Foundation of China (31501219). 照片 Tao Zheng | poster |
Neutrino quantum decoherence in supernovae explosions Vasily I. Bokov1, Konstantin L. Stankevich1, Alexander I. Studenikin1,2 1. Faculty of Physics, Lomonosov Moscow State University, Moscow 119991, Russia 2. Joint Institute for Nuclear Research, Dubna 141980, Moscow Region, Russia Correspondence: kl.stankevich@physics.msu.ru; studenik@srd.sinp.msu.ru 1 Introduction We study the influence of the neutrino quantum decoherence (see [1–4] and references therein) on collective neutrino oscillations. Collective neutrino oscillations is a phenomenon engendered by neutrino-neutrino interaction. It is significant in different astro- physical environments where the neutrino density is extremely high. Examples of such environments are the early universe, su- pernovae explosions, binary neutron stars, accretion discs of black holes. The effect of collective neutrino oscillations attracts the growing interest in sight of appearance of multi-messenger astron- omy and constructing of new large-volume neutrino detectors that will be highly efficient for observing neutrino fluxes from super- novae explosions. Previously, it was shown that neutrino quantum decoherence can significantly modify the neutrino fluxes from reactors and the sun. Here below we study the influence of the neutrino quantum de- coherence on supernovae neutrino fluxes. The peculiarity of the supernovae fluxes is that one of the main modes of neutrino oscil- lations in supernovae is engendered by the collective effects. We note, that previous works dedicated to collective neutrino oscilla- tions (see [5] and references therein) accounted only for the kine- matical decoherence. 2 Equations of motion Consider the two-flavor neutrino mixing scenarios, i.e. the mixing between νe and νx states where νx stands for νµ or ντ. Here below we focus on the derivation of the neutrino oscillation probability and highlight the interplay between collective neutrino oscillations and neutrino quantum decoherence. We use the simplified model of supernova neutrinos that was considered in [6, 7]. In such a model neutrinos are produced and emitted with a single energy and a single emission angle. The neutrino evolution in supernovae environment that accounts for neutrino quantum decoherence is determined by the following equation idρf dt = [H, ρf] + D[ρf] , id¯ρf dt = [ ¯H, ¯ρf] + D[¯ρf], (1) where ρf (¯ρf) is the density matrix for neutrino (antineutrino) in the flavour basis and H ( ¯H) are total neutrino (antineutrino) Hamiltonian. Neutrino quantum decoherence is described by the dissipation term D[ρ] that we define in the next section. Hamiltonian H contains the three terms H = Hvac + HM + Hνν, (2) where Hvac is the vacuum Hamiltonian, HM and Hνν are Hamil- tonians that describe matter potential and neutrino-neutrino inter- action correspondingly. In the flavour basis they are given by Hvac = δm2 4E −cos(2θ) sin(2θ) sin(2θ) cos(2θ) , (3) HM = √ 2 2 GFne 1 0 0 −1 , (4) Hνν = √ 2GFnν (1 + β)ρf −α(1 + ¯β)¯ρf , (5) where β represents the initial asymmetry between the electron and x-type neutrinos, and ¯β the asymmetry between electron and x- type antineutrinos, α is the ratio of electron antineutrinos relative to electron neutrinos, ne and nν describe the electron and neutrino density profiles. 3 Neutrino quantum decoherence In our previous studies [1–4] we developed a new theoretical framework that enabled one to consider a concrete process of parti- cles interactions as a source of the decoherence. In particular, in [1] a new mechanism of neutrino quantum decoherence engendered by the neutrino radiative decay. In parallel, another framework was developed [8, 9] for the description of the neutrino quantum decoherence due to the non-forward neutrino scattering processes. Both mechanisms are described by the Lindblad master equation in form [10,11]. In this paper we are are not interested in a specific mechanism of neutrino quantum decoherence. Therefore, we use the Lindblad master equation for the descr | poster |
DATABASE OF COPYRIGHT AND OPEN ACCESS SELF-ARCHIVING POLICIES OF POLISH SCIENTIFIC JOURNALS About: Only 79 publishers from Poland and only 319 policies of Polish journals are registered in the Sherpa/RoMEO database which shows copyright and Open Access self-archiving policies. At the same time, there are over 4,500 journals published in Poland. Not only do Polish authors have problems finding information about the policies of the other journals. This is often a big challenge for foreign authors. Lack of information or difficulty in accessing it also present problems for librarians who manage institutional repositories. Hence the idea of creating Database of Copyright and Open Access Self-Archiving Policies of Polish Scientific Journals which is to serve as a tool for authors and librarians. The database is also to supply the Sherpa/RoMEO database with current data. Self-Archiving Policies of Polish Scientific Journals Database Open Science Competence Center - Gdansk University of Technology Library Bridge of Knowledge Open Access resources Open Research Data Repository Virtual Microscope Open Access Journals Publishing Service PROJECT a an at a D ly t g ic i s B Our Team · 18 team members from GUT Library (different disciplines and specializations) How do we do it? · Checking a journal's websites and databases (e.g. DOAJ,SHERPA/RoMEO) · Contacting with the journals' publishers · Gathering information in our institutional CRIS, which is called My GUT · Providing public access to the content of the database on Bridge of Knowledge Platform · The database is a support for scientists who apply for research funding · It is a guide which shows relevant and verified information · It is a reliable source for information about how to select the most suitable journal for publication of an article · It shows different Open Access options dr Anna Wałek anna.walek@pg.edu.pl Benefits for libraries Our greatest challenges GUT LIBRARY The database is currently in the phase of development and will eventually be a part of the Bridge of Knowledge platform dedicated to Open Science Kamila Kokot kamila.kokot@pg.edu.pl authors: www.mostwiedzy.pl The Bridge of Data is co-financed by the European Regional Development Fund within the the framework of an Operational Programme Digital Poland for 2014-2020 · Checking the publishing policy · Selecting and verifying of information · Collecting data · Training and promoting of Open Science The role of Library's team Project in numbers · Starting point – October 2018 · Total number of Polish scientific journals: 4500 · Checked policies until June 2020: 1 376 · Verified policies: 950 · Open Access policies: 838 Benefits for researchers · The database is a convenient tool for librarians to support researchers It is a quick way to find relevant information from various sources · It is adapted to the new requirements set out by the most important · funding institutions in Poland (eg. National Science Centre, Ministry of Science and Higher Education) · Lack of information or incomplete information about the licenses and self-archiving policies on publishers' websites · Unobtainable websites and broken links · Lack of knowledge about Open Access aspects (problems with basic definitions, unawareness on topics dealing with copyright and CC licenses) · Lack of contact, or trouble contacting publishers https://orcid.org/0000-0002-3355-5198 https://orcid.org/0000-0001-8782-013X graphic design: Tytus Caban https://orcid.org/0000-0002-4391-7009 This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) Since the 2016 Gdańsk University of Technology implements a project called Multidisciplinary Open System Transferring Knowledge - the Bridge of Knowledge (pol. MOST Wiedzy). An essential part of the platform is the open repository of scientific publications, currently being developed towards a research data repository, as a part of the second stage of the project called The Bridge of Data. As part of the proj | poster |
Poster nr.: 421.08 −10 −5 0 5 10 value −10 −5 0 5 10 value -5 8 Natural History Placebo Video instructions and practice phase Placebo+Conditioning Standard task General Questionnaires Electrode preparation Waiting (10 min) Expectation Questionnaire 1 Standard task Manipulated task Experience Questionnaire 1 Sham tACS Expectation Questionnaire 2 Standard task Experience Questionnaire 2 Sham tACS Task 1 Task 2 Task 3 Block 2 Block 3 Anticipated (before) Experienced (after) decrease neutral improve decrease neutral improve 0 10 20 30 0 10 20 30 n Group NHG Placebo Placebo+Conditioning Expected and experienced changes in performance (forced choice) ● ● ● ● ● ● ● ● ● ● ● ● Anticipated (before) Experienced (after) 2 3 2 3 10 20 30 40 task value Group ● ● ● NHG Placebo Placebo+Conditioning Expected and experienced changes in performance (estimate) ● ● ● ● ● ● ● ● ● Total reward 1 2 3 200 300 400 task Reward Group ● ● ● NHG Placebo Placebo+Conditioning ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● alpha beta w NHG Placebo Placebo+conditioning −2 0 2 4 0.00 0.25 0.50 0.75 −0.5 0.0 0.5 1.0 1 2 3 1 2 3 1 2 3 val Task Task effects ● ● ●● ● ● ● ● ● ● 0.25 0.50 0.75 1.00 beta 0.25 0.50 0.75 1.00 alpha ● ● ●● ● ● ● ● ● ● 0.25 0.50 0.75 1.00 w 0.25 0.50 0.75 1.00 alpha ● ● ● ● ● ● ● ● ● ● 0.25 0.50 0.75 1.00 w 0.25 0.50 0.75 1.00 beta group 100 200 300 Expected Reward NHG Placebo Placebo+ Conditioning ● ● ● ● ● ● ● ● ● ● 0.1 0.2 0.3 0.4 beta 0.85 0.90 0.95 1.00 alpha ● ●● ● ● ● ● ● ● 0.3 0.4 0.5 0.6 0.7 w 0.85 0.90 0.95 1.00 alpha ● ● ● ● ● ● ● ● ● 0.4 0.5 0.6 0.7 w 0.1 0.2 0.3 0.4 beta q | poster |
@ F A C EITArcti c @ F A C EITArcti c @ fa c e _i t_arc tic @ The F A C E -IT Pro j e ct www.face-it-project.eu FACE-IT has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 869154. The Porsangerfjord in Northern Norway is a sub-arctic fjord with an inner arctic part and face an invasion by the red king crab Paralithodes camtschaticus since the end of the 1990’s. This offers the opportunity to study the dynamics of an Arctic ecosystem facing multiple stressors, i.e., climate change and invasive species. The Inner Fjord as a Refugium In the Porsangerfjord, fish species respond to climate change while bottom-living (= benthic) invertebrates are more threatened by invasive species such as the king crab. Fish diversity increases towards the inner fjord due to Arctic cold-adapted assemblages overlapping with newly arriving warm-adapted species. This effect was not observed in bottom- living invertebrates, yet the refuge function of the inner fjord might be unbalanced due to the red king crab’s predation on Arctic species. Red King Crab Paralithodes camtschaticus Climate Change Response in a Sub-Arctic Fjord: Fishes and Invertebrates Respond DifferentlyLaurène Mérillet1,2, Morten D. Skogen1,2, Frode Vikebø1,2, Lis LindalJørgensen3 1Institute of Marine Research, Bergen, Norway 2Bjerknes Centre for Climate Research, Bergen, Norway 3Institute of Marine Research, Tromsø, Norway Berengere.Husson@hi.no The main environmental changes in the fjord were: • freshening of the water • increase of the seabed current • decrease of the maximum sea ice extent. Species richness and diversity of fishes significantly increased into the fjord, due to the arrival of warm-water species over time that overlapped with cold-water species that have seen their biomass significantly reduced. No significant decrease in the biomass of the cold-water benthic (= sea floor associated) species was visible, which could indicate an efficient refugee effect of the inner fjord. Sampling areas between 2007 and 2019 Examples of bottom-living invertebrates Get Mérillet et al. 2022 | poster |
Department of Computer Science, University of Helsinki Tommi Meskanen and Valtteri Niemi (tommi.meskanen@helsinki.fi, valtteri.niemi@helsinki.fi) Trust, Security and Privacy for HELIOS HELIOS is an EU Horizon 2020 project • duration of 3 years • budget 5 million euros • 15 partners around Europe, both industrial and academic HELIOS is a social media platform that is • modular • peer-to-peer • open-source • open for developers to build their apps on One of the main concepts of HELIOS platform is Trust. • Trust level is automatically calculated for other users the ego connects to. • Trust level is calculated based on the frequency and level of interactions between the ego and other users. No central authority. Security is based on encryption and authentication using the public keys that every user has and that are shared to their friends. For Privacy • all communication between users is end-to-end encrypted • all files on the users’ devices are encrypted HELIOS is able to identify the Context the user (Ego) is in. Based ot the context HELIOS decides which friends (Alters) or activities should have priority. The HELIOS platform enables users to create Ad Hoc groups • users can join and leave. • all communication in the group is again encrypted • people outside the group cannot read it | poster |
A Finite Element Study on the Biomechanics of Intracorneal Implants in Keratoconus Corneal Models Shima Bahramizadeh Sajadi1, Hamid Reza Katoozian2, Philippe Büchler3 1,2Department of Biomedical Engineering, Polytechnic of Tehran, Tehran, Iran 1,3Computational Bioengineering, ARTORG Center for Biomedical Engineering Research Introduction • Keratoconus (KC) is a progressive corneal disease characterized by thinning, weakening and steepening of the cornea. • KC progression is manifested by corneal protrusion, irregular astigmatism and severe unilateral and bilateral myopia. • The prevalence is 0.05% in Western countries but higher in the Middle East and Asia (0.76% - 3.30%). • KC-associated anatomical deviations strongly impact the patient’s vision and quality of life. • The etiology of KC is not well understood and there is no cure. • Corneal geometric alterations affect ophthalmic surgical plans. • Intracorneal ring segment (ICRS) implantation proved to be a clinically effective approach in retrieving the corneal curvature in more advanced stages of the disease. • Empirical nomograms are used by clinicians to define the surgical planning. Nomograms provide a homogenized view of the treatment. GOALS → Ring implant simulations in prediction of post-surgical deformation and internal stresses → To investigate geometrical features of ICRS surgeries to propose personalized sets of segments based on each patient’s corneal topographic maps Results and Discussion • Generic models Methods • A round, central KC cornea was modeled with physiological intraocular pressure. • Combination sets of ICRS implants were considered. References [1]. Flecha-Lescún, et al., Biomech Model Mechanobiol, 2018: pp. 1-16. [2]. Ariza-Gracia, 2020. Transl. Vis. Sci. Technol., 9(11), pp.26-26. [3]. Kling, S. and Marcos, S., Invest Ophthalmol Vis Sci, 2013. 54(1): pp. 881-889. [4]. nkcf.org, National Keratoconus Foundation Gallery. Ongoing/Future Work • Patient-specific models • Characterizing mechanical properties of corneas | poster |
NuSTAR results + conclusions Methods Motivations Mathematisch- Naturwissenschaftliche Fakultät Using Vela X-1 to understand accretion and wind structure in High-Mass X-ray binaries (HMXBs) 60 58 56 54 52 50 48 12 10 8 6 4 2 35 30 25 20 ECRSF,H [keV] Luminosity [1036erg s−1] ECRSF,F [keV] 1 0.8 0.6 0.4 0.2 0 100 80 60 40 20 0 CF NH,1 [1022cm−2] • Vela X-1: convenient physical parameters (close distance, high inclination, small orbital separation) which facilitate the observation and analysis of the system • Two observations taken on January (NuSTAR) and May 2019 (simultaneous NuSTAR+XMM-Newton) at orbital phases ~0.68–0.78 and ~0.36–0.52, respectively 0.6 0.4 0.2 0.0 0.8 0.6 1400 1200 1000 800 600 400 200 0 Rate [mCrab] Phase single-absorption model best-fit model without 10 keV feature best-fit model without CRSF best-fit model 1 0.1 0.01 10-3 a) 0 b) 1 0.5 c) 1.2 1 d) 70 50 30 20 15 10 7 5 4 3 1.2 1 Counts s−1 keV−1 χ Ratio Ratio Energy (keV) Ratio References XMM-Newton PN analysis • Preliminary XMM-Newton results showing a strong variation of the absorption column density of the stellar wind along the orbital phase when the wakes are passing through the line of sight • drops after flaring episodes, which can be explained by accretion of clumps thus reducing the density of the material. NH,1 [1] C.M. Diez, V. Grinberg, et al. 2022, Continuum, cyclotron line, and absorption variability in the high-mass X-ray binary Vela X-1, A&A 660, A19 [2] El Mellah, et al. 2018, Accretion from a clumpy massive-star wind in supergiant X- ray binaries, MNRAS 475, 3240–3252 [3] Mushtukov, et al. 2014, On the origin of cyclotron lines in the spectra of X-ray pulsars, EPJ Web of Conferences 64, 02005 [4] Fürst, F., Pottschmidt, K., Wilms, J., et al. 2014, NuSTAR discovery of a luminosity dependent cyclotron line energy in Vela X-1, ApJ, 780, 133 [5] C.M. Diez, V. Grinberg, I. El Mellah, et al., paper in prep. [3] [1] Fig. 6: Spectral parameter as function of the 3-79 keV luminosity based on our orbit-by-orbit spectroscopy results ( for observation I, for observation IIa, and for observation IIb) together with ks-integrated spectral fits from Fig. 7 in [4] ( ). Upper panel: photon index . The black dot-dashed line is a linear regression through all data points, meant to guide the eye. Middle panel: energy of the harmonic cyclotron line . The black solid line is the theoretical prediction for = 1, = 30 keV and = 1.9 . The above and below dot-dashed lines are for = 1.7 and = 2.1 respectively. Lower panel: energy of the fundamental line . Γ ECRSF,H Λ ENS MNS M⊙ MNS M⊙ MNS M⊙ ECRSF,F Fig. 5: Stellar wind absorption as function of the covering fraction based on our orbit-by-orbit and pulse-by-pulse spectroscopy results. are the results of the orbit-by-orbit analysis and of the pulse- by-pulse analysis both for observation I, are the results of the orbit-by- orbit spectroscopy and of the pulse-by-pulse spectroscopy both for observation IIa, are the results of the orbit-by-orbit spectroscopy and X of the pulse-by-pulse spectroscopy both for observation IIb. NH,1 CF Fig. 4: NuSTAR 3–79 keV flux for observation I (red) on January 2019 and observation II on May 2019 (blue) and Swift/BAT 15—50 keV flux averaged over all data since 2005 (black solid line) plotted over the neutron star’s orbital phase where 0 is defined with T90. Fig. 3: Time-averaged spectrum for observation I. FPMA data in red and FPMB data in blue, models for both focal plane modules are shown in the same color and are hardly distinguishable with the naked eye. The first panel shows the count spectrum. Top-down description of the residual panels: a) best-fit model (black), b) best-fit model with CRSFs (yellow) turned off but not fitted again, c) best-fit model with 10-keV feature (green) turned off but not fitted again, d) single-absorption model (magenta). C. M. Diez1, V. Grinberg1,2, F. Fürst3, E. Sokolova-Lapa4,5, A. Santangelo1, J. Wilms4, K. Pottschmidt6,7, S. Martínez-Núñez8, C. Malacar | poster |
A High Resolution H- and K-Band Spectroscopic Sequence of Ultracool Dwarfs Jennifer J. Greco1,2,3, Michael C. Cushing3 1. Uppsala University, 2. The Swedish Collegium for Advanced Study, 3. University of Toledo To see the full online interactive version of this poster scan this QR code or go to: http://astro1.panet.utoledo.edu/~jgreco/posters/cs20p5 •Ultracool dwarfs have been studied extensively using photometry and low- and moderate-resolution spectroscopy, but rarely using high-resolution spectroscopy. •We have assembled the first high-resolution H- and K-band spectroscopic sequence of ultracool dwarfs. Our sample contains 31 objects with spectral types ranging from M1.5V to T6, and also contains low-gravity objects at five spectral types (M9, L0, L1, L2, L3, L5). •All spectra were obtained using the Immersion GRating INfrared Spectrometer (IGRINS) on the 4.3 meter Lowell Discovery Telescope at a resolving power of R~45,000. • We compared 22 of our objects to synthetic spectra created from the atmospheric models of Saumon & Marley 2008. •We fit both the whole K-band (2.05-2.35𝜇m) and the CO band (2.27-2.35𝜇m), to obtain estimates of Teff, logg, vsini, fsed for our objects. • Shown here as an example are the CO band and K-band fits for the T2.5 dwarf SIMP0136+09. The best fitting model for each is shown in cyan. • We find that our Teff values (shown in blue) are high when compared to those calculated using photometry by Filippazzo et al 2015 (shown in black) but agree well with those found using the same models at moderate resolution by Cushing et al 2008 (shown in red). •We also find that the Teff values obtained in the CO band are all greater than or equal to those obtained in the K-band. •We find similar systematic differences between the values of logg, vsini, and fsed from the K-band and CO band fits (see online version of poster for more information). •We are still investigating the cause of these systematic differences. If you have any questions please email jennifer.greco@physics.uu.se | poster |
0 1 2 3 4 5 10 15 20 25 0 1.6875 3.375 6.75 12.5 25 50 100 Generation Crossed to Domestic % Bengalness Theoritical Asian Leopard Cats BxL LxD BxD Random Bengal Breed cats % Bengalness 0 25 50 75 100 ALC LxD BEN ACURL BOM BUR CREX EGY MANEE PERM MCOON MUNCH ORI PBALD RBLUE SREX SIR SPH VAN BxL BxD ABY BIR BSH CHR DREX JBOB KOR LYK MANX NFC PER RAG SFOLD SIA SOM TREX WIR Findings: 1) Department of Biological Science, Kuwait University, Kuwait 2) College of Veterinary Medicine, University of Missouri-Columbia, Columbia, MO 3) Department of Population Health & Reproduction, University of California - Davis, Davis, CA Degree of Bengalness: A measure of the measure of genomic contribution of Asian Leopard Cats into Bengal breed cats Mona Abdi1, H. Alhaddad1, B. Gandolfi2 R. Grahn3, and L. A. Lyons2 Dataset & Analysis: The idea & Significance • The Bengal breed cats result from hybridizing domestic cats (DOM) and Asian Leopard Cats (ALC). • First generation hybrids can be further crossed to domestic cats and still be considered Bengal cats as long as phenotypic and behavioral characteristics retained (see cat below). • The ALC genomic contribution into registered Bengal cats is usually unknown and likely variable. • Significance of the study: 1. Develop a panel of diagnostic markers to measure ALC genomic contribution in Bengal cats (degree of Bengalness). 2. The panel can be used to study the genetics of the Asian Leopard cat and the ALC-DOM introgression zones in the wild. Dataset: • A total of 2161 cats (from 48 breeds/populations) genotyped using the 63K Feline SNP array were used. • ALC (N = 9) and domestic cats (N = 1765). • Calculate the allele frequency for each marker in each group independently. • Select the markers that are fixed with allele 1 (A1) in ALC and absent in domestic cats or have a minor allele frequency < 0.05. • Evaluate the positions of the selected markers. • Select a subset of the identified markers with near uniform inter-marker distances. Objective 1: Identify diagnostic markers that are fixed for different alleles in the two groups (ALC & DOM) 1. 674 markers were identified as diagnostic markers and they were distributed in all 19 cat chromosomes (Fig. 1a). 2. To avoid markers being in linkage disequilibrium, 287 were selected with an inter-marker distance ~ 5 Mb (Fig. 1b). Fig.1: Distribution of ALC specific markers along cat chromosomes. (a) Relative positions of all markers identified. Many markers are close to one another and may be in linkage disequilibrium. (b) Relative position of a subset of markers from (a) where markers are ~ 5Mb apart. SNP Relative Position (Mb) A1 A2 A3 B1 B2 B3 B4 C1 C2 D1 D2 D3 D4 E1 E2 E3 F1 F2 X 0 25 50 75 100 125 150 175 200 225 250 a. SNP Relative Position (Mb) b. 0 25 50 75 100 125 150 175 200 225 250 Objective 2: Estimate the genomic contribution of ALC in: (1) known pedigree, (2) Bengal breed, (3) Other cat breed Dataset & Analysis: • Diagnostic panel (All: 287 markers, Auto: 262 markers). • ALC-DOM pedigree (N = 98), random Bengal cat (N = 98), and 33 cat breeds (N = 1452). • Calculate % of ALC alleles (% bengalness) in each individual using autosomal markers only. • Using known pedigree samples, estimate range of % bengalness and validate the estimates using pedigree information. Fig. 2: Genomic contribution of ALC. (a). Known pedigree crosses of ALC-DOM. LxD: first generation hybrid. BxL: backcross to ALC. BxD: backcross to DOM. BEN: Bengal cat unknown pedigree (b). Percent bengalness in known pedigree, random bengal cats, and other cat breeds. ALC DOM LxD BxL BxD BEN a. b. Findings: 1. Known ALC-DOM pedigree (Fig. 2a) provides information about theoretical % bengalness. In pedigree samples, theoretical and observed are similar (Fig. 2b, Table 1). 2. Random Bengal cats on average have ~ 7% benglness whereas other cat breeds, combined, exhibit ~ 1% with some variations (Table 1). 3. Proportion of ALC into Bengal cats is unmatched by any of the other breeds with the | poster |
4TH PRESS RELEASE 2ND Annual Meeting of A.I.M.S. Cluster The A.I.M.S. Cluster takes its name by its 4 founding projects: Algae4IBD, InnCoCells, MARBLES and SECRETed, which are funded under the same EU topic: FNR-11-2020: Prospecting aquatic and terrestrial natural biological resources for biologically active compounds. The A.I.M.S. Cluster aims to bridge the gaps among the 4 projects by sharing knowledge about common challenges and identifying complementary activities. The projects also effectively cooperate in terms of dissemination activities (social media, conferences and scientific publications) enlarging their audiences’ volume. Sustainable Exploitation of bio-based Compounds Revealed and Engineered from naTural sources COPYRIGHT© Algae-based bio compounds for prevention & treatment of inflammatory bowel disease Bioactive cosmetic ingredients based on underutilized engineered plant resources Marine microbes for drug discovery and sustainable production of fish and crops Engineered strains for industry-driven biosurfactants and siderophores production The SECRETed project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Grant Agreement No. 10100079. This publication reflects only the author’s views and the European Union is not liable for any use that may be made of the information contained therein. | poster |
iAtlas Tour of Modules Immune Checkpoint Inhibitor Trials Meet the Team CRI iAtlas is made possible through collaboration between the Cancer Research Institute (cancerresearch.org), Sage Bionetworks (sagebionetworks.org), the Institute for Systems Biology (isbscience.org), and the Vincent Lab (unclineberger.org/vincentlab) at the UNC Lineberger Comprehensive Cancer Center. Our team combines expertise in software design and engineering, bioinformatics, computational biology, immuno-oncology and immunogenomics. David L. Gibbs, Carolina Heimann, Andrew E. Lamb, Dante Bortone, Thomas Yu, Brad Macdonald, Milen Nikolov, Adam J. Taylor, Amy Heiser, Steven P. Vensko II, Susheel Varma, Vesteinn Thorsson, Benjamin G. Vincent Accelerating cancer immunotherapy research with the CRI iAtlas data resource and web portal New IO Data Types CRI iAtlas is grateful for support from the Cancer Research Institute. All references cited here are listed, along with a PDF version of this poster, in Figshare at https://doi.org/10.6084/m9.figshare.26932027 Immune Landscape of Cancer Amy Heiser Milen Nikolov Thomas Yu Immuno-oncology (IO) is one of the most promising areas of cancer research, with IO-based treatments demonstrating high efficacy within certain cancer types and subsets of patients. The Cancer Research Institute (CRI) iAtlas1 (cri-iatlas.org) is a platform for interactive IO data exploration and discovery, originating in a pan-cancer working group study by the Cancer Genome Atlas (TCGA)2, exploring the relationship between tumors and the immune microenvironment and its impact on patient outcomes. iAtlas provides topic-oriented analysis modules using the R/Shiny4 framework, each generating visualizations and statistics for studying interactions between tumors and the immune microenvironment. Using single cell data we have three new modules, UMAP, Immune Features, and Immunomodulators. Vésteinn Þórsson David Gibbs Carolina Heimann Andrew Lamb Benjamin Vincent We continue to expand the breadth of data in iAtlas, including newly published ICI trials with accompanying outcome data, as well as large-scale cancer -omics datasets such as the Human Tumor Atlas Network11. Dante Bortone Steven Vensko Models and notebooks We aim to make iAtlas a platform that both democratizes analysis for IO researchers and enables contributions from tool developers or data scientists. Everything we build is intended to follow FAIR principles, to advance and accelerate discovery in combating cancer. Expanding iAtlas functionality. Examples of newer modules include (above) a Cytoscape6-powered module showing how receptor-ligand interactions mediate interactions among tumor and immune cells and right iAtlas development has been generously supported by CRI since 2017 iAtlas analysis modules. (left) Interactivity enables users to explore different views or “drill down” into results. (right) List for either large-scale genomics datasets or harmonized ICI study data are driven by flexible features for cohort selection. iAtlas is working hard to ramp up new data ingestion! Among the various data types we host, we've added single cell RNA-seq, with a focus on immuno-oncology studies. In our beta version (in test now), we have six new data sets that come from the Human Tumor Atlas Network (HTAN) and other public resources. Acknowledgement, References & Contact (Above) For ICI datasets with DNA- and RNA-seq data available, the Vincent Lab has developed a workflow (using Nextflow DSL2) to predict tumor antigens derived from a comprehensive set of genomic sources. The Landscape of Effective Neoantigens Software (LENS)21 workflow provides a portable and reproducible process for deriving these data for use in translational applications. In the TCGA study3, we identified six immune subtypes—associated with differences in somatic aberrations, microenvironment, and survival—that span cancer types and molecular subtypes. For each sample, we characterized the tumor microenvironment in terms of | poster |
KEY ART-RESEARCH-EXHIBITION PROJECT • IMAGES OF IDENTITY (2020–21) This project combined the visual arts with interdisciplinary research in the humanities and social sciences, focusing on the question of ‘identity’. To explore this theme, the conference was divided into five thematic panels, each presenting the creative perspectives of five artists exhibiting at the BPA. The exhibition and the accompanying conference ‘Our Everyday Identity’ were part of the interdisciplinary research project ‘The Question of ‘Identity’ in an Interdisciplinary Approach’. Organised by BPA, PUNO and the University of the National Commission in Krakow (UP, Poland). Side events: guided tours of the exhibition with curators, artists’ talks, an international conference and the publication of selected artworks and texts in an academic journal. VIRTUAL GALLERY A Nexus of Artistic Practice and Research Authors: Dr Justyna Gorzkowicz, Email: justyna.gorzkowicz@puno.ac.uk, ORCID: 0000-0003-1139-2137 MA Jarosław Solecki, Email: jaroslaw.solecki@puno.ac.uk, ORCID: 0000-0002-5929-2023 DARIAH Annual Event 2024, Lisbon, Portugal KEY ART PROJECTS • THE DYSTOPIA OF IMITATION (series of artworks by Jarosław Solecki, 2021–23) Supported by Arts Council England, this project evolves from a virtual installation to augmented reality (AR). It features an animated 3D sculpture inspired by Johannes Vermeer’s ‘The Milkmaid’, blending traditional sculptural techniques with digital methods to create a generative AR art object. This project demonstrates the potential of virtual galleries and AR to broaden access to art, foster global collaboration, and democratise the art process. Side events: guided tour of the exhibition with the curator, artistic talk, e-book. • CYPRIAN NORWID’S SKETCHES (2021–23) Featuring sketches by Polish poet and artist Cyprian Norwid, this exhibition underlines the gallery’s commitment to non-commercial activities and its role as a nexus of artistic practice and research. Developed as part of the larger project ‘Norwid in Great Britain’ by PUNO, the Union of Polish Writers Abroad in London, and the University of Warsaw. Side events: guided tour of the exhibition with curators and e-book launch, research element: international conference and post-conference monograph; educational component: online lectures with young students, including presentation of a virtual exhibition, series of short documentary films tracing Norwid’s footsteps in London, telling the story of the poet’s emigrant legacy, closing symposium. INTRODUCTION Blue Point Art Gallery London (BPA) places the arts and humanities at the heart of a technologically evolving society. Our mission is to bridge the gap between artists and researchers, promoting open and accessible knowledge about culture and society. BPA brings together a diverse team skilled in the visual arts, digital technologies and humanities, enabling us to create innovative and interactive projects that engage audiences. Our expertise includes theoretical and methodological research, providing artistic and cultural anthropological context to contemporary activities, and publishing scholarly work. We see digital technology as a powerful tool for exploration and development, tailoring our projects to meet the specific needs of each initiative. This approach values the diversity of research ecosystems and artistic activities, enriching the wider research community. Our gallery serves as a small experimental platform for knowledge exchange, fostering a collaborative and inclusive environment. While our focus is on Polish culture, we aim to provide broad access to knowledge about heritage in an international context. Our practices have the potential for significant impact, advancing the scholarly, artistic and cultural heritage for the public interest. BPA projects are divided into three main types: artistic projects, research- exhibition projects and art-research-exhibition projects. • WAKE-UP CALL (winning posters from the 11 | poster |
Evaluation of the Types of Farms and Their Effects on the Development of Asthma and Allergies INTRODUCTION The purpose of this study is to determine the factors that are significantly involved in reducing asthma risk in farm environments. CONCLUSION FUTURE IMPLICATIONS Meram Alamoudi1, Shandra Bellinger1, Armando Marull1, Melany Santana1, Felix E. Rivera-Mariani, PhD1 1College of Biomedical Sciences, Larkin University According to the WHO, asthma is the most common non- communicable disease among children with approximately 235 million people suffering worldwide. It has skyrocketed in recent decades, specifically in urban and modernized environments globally. Epidemiological studies have demonstrated that children who grew up in rural areas have less asthma than those in urban environments. This study aims to discuss the various factors that are instrumental in reducing the susceptibility of asthma and allergies in children that were exposed to living on farms in the United States. There have been limited studies comparing asthma risks in children who grew up in farm environments in the U.S. as there aren’t many that have been done nationally in every single state. This poses a problem in attempting to produce a more accurate depiction of the patterns associated with lower asthma rates in children and farm exposure. Figure 2 Showcases the asthma rates of the states with the highest number of farms (Texas), lowest number of farms (Alaska), and a state in the middle (Louisiana). More studies need to be conducted to determine accurate comparisons of asthma-reduction effects with difference types of farms (in example, agricultural farms versus traditional farms). Does the climate the farms are in matter in asthma prevalence? • All research articles reviewed in this study suggest that farms have a positive effect on the development of both allergies and asthma in children. • The Hygiene Hypothesis is a theory suggesting that an environment that is too clean will not expose those in it to enough allergens needed to build their immune system. • The endotoxin that is in farm dust and produced by bacteria is present in most types of farms; allowing farms to act as protective environments against allergy development. • The types of farms reviewed are dairy farms, poultry farms and crop farms, and in all settings, children exposed were less likely to develop allergies as adults. • Data suggest that the exposure to animals on the farm (dairy and poultry farms) help to reduce the risk of allergy and asthma development. • The location (by state) of the farm does not seem to influence the effectiveness of the farm dust as protection, as each study reviewed farms in different states. • Industrialized and traditional farming practices displayed consistent findings however traditional farms had a greater impact. • Asthma rates per state reported by the CDC were compared against the number of farms reported per state; Texas had the most amount of farms and lowest percent with current asthma • Childhood exposure to farms will help decrease the occurrence of allergies and asthma. Figure 1 Figure 2 The following are differences that were present in the various studies reviewed but the relationship between farming and decreased risk of developing Asthma and Allergies is consistent: • Dairy, poultry and crop farms • Location of the farm (different states) • Industrialized vs. traditional farming practices • Exposure to animals on a farm These findings indicate that there is no significance in the type of farm the child is exposed to or the location of the farm. The results denote that the farm dust present will act as protection against the development of asthma and allergies when the child is exposed at a young age. PURPOSE METHODS RESULTS DATA LIMITATIONS Figure 1 Showcases the states with the highest number of farms (Texas), lowest number of farms (Alaska), and a state in the middle (Louisiana). | poster |
A Milestone-Based Approach to Monitoring Disease Progression in Parkinson’s Disease Michael C. Brumm,1 Andrew Siderowf,2 Tanya Simuni,3 Elliot Burghardt,1 Chelsea Caspell-Garcia,1 Arthur W. Toga,4 Douglas Galasko,5 Brit Mollenhauer,6,7 Lana M. Chahine,8 Tatiana Foroud,9 Vanessa Arnedo,10 Mark Frasier,10 Alyssa Reimer,10 Caroline Tanner,11 Kathleen Poston,12 Daniel Weintraub,2,13 Samantha J. Hutten,10 Karl Kieburtz,14 Kenneth Marek,15 and Christopher S. Coffey1 1University of Iowa, Iowa City, IA, USA; 2University of Pennsylvania, Philadelphia, PA, USA; 3Northwestern University, Chicago, IL, USA; 4University of Southern California, Los Angeles, CA, USA; 5University of California, San Diego, CA, USA; 6University Medical Center Goettingen, Goettingen, Germany; 7Paracelsus-Elena-Klinik, Kassel, Germany; 8University of Pittsburgh, Pittsburgh, PA, USA; 9Indiana University, Indianapolis, IN, USA; 10The Michael J. Fox Foundation for Parkinson’s Research, New York, NY, USA; 11University of California, San Francisco, CA, USA; 12Stanford University, Stanford, CA, USA; 13Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, USA; 14University of Rochester, Rochester, NY, USA; 15Institute for Neurodegenerative Disorders, New Haven, CT, USA OBJECTIVE RESULTS DESIGN/METHODS Clinical features at baseline that predicted reaching at least one milestone included increasing age (p<0.0001), greater MDS-UPDRS total score (p<0.0001) and greater depression score on the GDS-15 (p=0.0341). Biomarker predictors of reaching a milestone included decreasing DAT SPECT binding (p=0.0043) and CSF lower total alpha-synuclein (p=0.0033). Dopaminergic treatment was not significantly associated with the endpoint (p=0.1639). To assess the frequency of progression to clinically meaningful disease milestones and examine baseline predictors of reaching these milestones in early Parkinson’s disease (PD) using Parkinson Progression Marker Initiative (PPMI) data. CONCLUSIONS Clinically relevant milestones occur frequently within five years of follow-up even in early PD, and are associated with baseline clinical and biological markers, but not significantly associated with dopaminergic treatment. The results of this analysis are relevant for patient selection and outcome assessment in clinical trials. Funding agencies: PPMI – a public-private partnership – is funded by the Michael J. Fox Foundation for Parkinson’s Research funding partners 4D Pharma, Abbvie, Acurex Therapeutics, Allergan, Amathus Therapeutics, ASAP, Avid Radiopharmaceuticals, Bial Biotech, Biogen, BioLegend, Bristol-Myers Squibb, Calico, Celgene, Dacapo Brain Science, Denali, The Edmond J. Safra Foundaiton, GE Healthcare, Genentech, GlaxoSmithKline, Golub Capital, Handl Therapeutics, Insitro, Janssen Neuroscience, Lilly, Lundbeck, Merck, Meso Scale Discovery, Neurocrine Biosciences, Pfizer, Piramal, Prevail, Roche, Sanofi Genzyme, Servier, Takeda, Teva, UCB, Verily, and Voyager Therapeutics. BACKGROUND Assessment of time to clinically relevant milestones could serve as a composite endpoint in clinical trials and be implemented in trials including patients receiving dopaminergic treatment. We measured 25 milestones across six domains: “walking and balance”; “motor complications”; “cognitive”; “autonomic”; “functional independence”; and “activities of daily living.” Milestones reflected severe manifestations of a given problem (e.g., a score ≥ 3 on relevant MDS-UPDRS items). Progression Milestone Assessment(s) Criteria Walking and Balance Domain Walking and Balance MDS-UPDRS Item 2.12 Response ≥ 3 Freezing MDS-UPDRS Item 2.13 Response ≥ 3 Gait MDS-UPDRS Item 3.10 Response ≥ 3 (ON or OFF) Freezing of Gait MDS-UPDRS Item 3.11 Response = 4 (ON or OFF) Postural Stability MDS-UPDRS Item 3.12 Response ≥ 3 (ON or OFF) Hoehn and Yahr Stage Hoehn and Yahr Stage Response ≥ 4 (ON or OFF) Motor Complications Domain Dyskinesias MDS-UPDRS Items 4.1 and 4.2 Response ≥ 3 (on BOTH) Fluctuations (Functiona | poster |
Result 4 – PS-Eu affects surfactant secretion/production and boosts metabolic activity in Sub and ALI samples, while changing cell morphology (TEM) in ALI (increased authophagy and protein aggregation, reduced Mitochondria/ER contacts and lamellar bodies). Sub samples ultrastructure is still under evaluation. No effect on barrier integrity, PS-Eu translocation or cytotoxicity was found. Result 2 – PS-Eu affect acidic organelle activity (NRU) in a dose-dependent manner and are uptaken by A549 grown under standard submerged conditions (culture method A). 600nm * N LD * PS-Eu 50 µg/ml PS-Eu 100 µg/ml 200nm Control LB * PS-Eu 25 µg/ml 200nm 600nm Particle uptake (TEM) Impact of Polystyrene Nanoparticles on Lung Epithelial Barrier Formation and Functionality Sara Michelini, Neža Repar, Ema Kurešepi, Katarina Šimunović, Francesco Barbero, Martin Schicht, Katharina Jüngert, Victor Ganin, Ivana Fenoglio, Friedrich Paulsen, Andreja Erman, Barbara Šetina Batić, Ines Mandič-Mulec, Anita Jemec Kokalj, Damjana Drobne. Background: Micro- and nanoplastics (MNPs) are one of the most widespread pollutants of our time. They can be manufactured in specific sizes for a specific purpose or be released into the environment through the degradation of plastic products. Humans are generally exposed to MNPs via two main routes: food ingestion or inhalation of air. In the latter case, it has already been reported that airborne particles can enter and accumulate in the lower respiratory tract, leading to occupational diseases. This study aims to assess the impact of 274 nm europium-doped polystyrene (PS-Eu) particles on the integrity and functionality of the lung barrier, especially in terms of surfactant production. The presented results were produced both on A549 cells grown in “standard” submerged (Sub) conditions as well as by performing the assays in Air-liquid interface conditions (ALI) using transwells which resemble more closely the real-life settings. Result 3 – Model characterization. Epithelial barrier forms 10 days post seeding. After 17 days ALI-grown A549 produce more surfactants, and have more microvilli than Sub cells. hello@plasticsfate.eu www.plasticsfate.eu plasticsfate Linkedin.com/groups/12519441 PlasticsFatE has received funding from the European Union’s Horizon 2020 Research and Innovation programme, under the Grant Agreement number 965367 Conclusion and outlook: PS-Eu has been found able to increase acidic organelle activity and, in cells grown on transwells, also surfactant production and metabolic activity. Additionally in ALI, which is a more physiological model, TEM analysis revealed that PS-Eu caused a dose-dependent reduction of both LB and mitochondria-ER contacts (structures known to be critically involved in surfactant production/secretion), possibly by inducing autophagy upon uptake. Many LB were in fact found in autophagic vacuoles. Taken together these results may indicate that PS-Eu, upon uptake, are able to affect LB trafficking, vesicle acidification and mitochondria/ER activity causing a dose-dependent reduction of intracellular surfactant production which possibly will affect, at later timepoints, the extracellular surfactant pool, which is up to now not drastically affected with the exception of SP-D and SP-D. Sub samples ultrastructural analysis might shed more light on the mechanisms underlying the shown effects. Acknowledgements: Method images were created with BioRender.com. Figure 2: Impact of different concentrations of PS-Eu on A549 cells in terms of A) cytotoxicity (LDH assay), B) metabolic activity (Resazurin assay), C) protein content (CBB assay) and D) acidic organelles activity (Neutral Red Uptake assay). Particle uptake was confirmed via TEM E). LB, lamellar body; N, nucleus; LD, lipid droplet; asterisk, PS-Eu. Figure 3: Model characterization. A) OT permeability and TEER of A549 cells grown in ALI or submerged conditions on transwells (culture method B). B) Confocal microscopy showing OT barrier for | poster |
Betreuung: Prof. Dr.-Ing. Nils Jensen & Prof. Dr. rer. nat. habil. Torsten Sander Vorhaben einer Masterarbeit im Online-Masterstudiengang Medieninformatik Jens Gäbeler Fakultät Informatik ENTWICKLUNG EINER STEUERUNGSKOMPONENTE ZUR PRIORISIERUNG VON AUFTRÄGEN FÜR VERTEILTE WEBCRAWLS Motivation Mithilfe des Open Web Index (OWI) möchte die Open Search Foundation eine europäische Alternative zu den kommerziellen Webindizes der Firmen Google, Microsoft, Baidu und Yandex schaffen. Dieser Index als öffentliche Infrastruktur soll von europäischen Organisationen genutzt werden können, um vielfältige Dienste erstellen und anbieten zu können. Die geplante modulare Bauweise des OWI (siehe Abbildung 1) ermöglicht die Konzentration auf einzelne Aspekte, wie zum Beispiel das in der Masterthesis zu bearbeitende Thema der Priorisierung und Verteilung von Crawlaufträgen. Fragestellung Vor der Erstellung einer Steuerungskomponente zur Priorisierung entstehen die folgenden wissenschaftlichen Fragen: Vorgehensweise Die Masterthesis durchläuft geplant 5 Phasen (siehe Tabelle 1). Davon finden die ersten beiden Phasen parallel statt, die weiteren Phasen laufen konsekutiv. Zeitplanung Der Beginn der Masterarbeit ist der 19.09.2019. Das späteste Abgabedatum ist der 23.07.2020. Dies entspricht einer Bearbeitungszeit von 44 Wochen in Teilzeit. In Abbildung 3 sind die geplanten Arbeitspakete und deren Zeiten dargestellt. Stand der Arbeit Organisatorisch Die Literaturrecherche erweist sich als umfangreicher als während der initialen Planung gedacht. Daher wurde der Zeitplan für die ersten beiden Phasen um zwei Wochen verlängert. Im Gegenzug wird der zeitliche Rahmen der Realisierung gekürzt. Abbildung 3 zeigt die aktuelle Version. Wissenschaftliche Erkenntnisse (Phase 1) Mit der Methode SLR (Systematic Literature Review) werden zu den Forschungsfragen passende wissenschaftliche Arbeiten gesucht, kategorisiert und ausgewertet. Zum aktuellen Stand wurden die folgenden relevanten Arbeiten identifiziert: Des Weiteren wurden die folgenden Grundlagenwerke zur umgebenden Recherche des Themas ermittelt: Technische Bereitstellung (Phase 2) Die OWI Architektur wurde analysiert und folgender Einhängepunkt der zu entwickelnden Steuerungskomponente identifiziert: Für die Realisierung wird Python und das Microframework Flask verwendet. Python eignet sich durch die umfangreichen Funktionen seiner Standardbibliothek und durch eine Vielzahl an Bibliotheken zur Berechnung (z.B. Numpy, SciPy), Datenhaltung (z.B. Pandas) und bei Bedarf Künstlicher Intelligenz (z.B. SciKit, Keras, TensorFlow). Das Microframework Flask eignet sich sehr für die Erstellung einer Anwendung, die über eine REST API zur Verfügung gestellt wird. Phase Methode Ziel 1. Akademische Analyse SLR & Kriterienaufnahme Katalog mögl. Priorisierungs- und Evaluationstechniken 2. Techn. Vorbereitung Bereitstellung der techn. Umgebung Erstellung einer Minimalversion 3. Entwurf Umsetzung auf Basis von 1) Funktionsentwurf & Prozessentwurf 4. Realisierung Umsetzung auf Basis von 3) Prototyp 5. Evaluation Vergleich Ranking [1] Huss, N.; Lewandowski, D.; Sander-Beuermann Wolfgang; Ude, A.: Proposal for an Open Web Index, Hannover 2017. https://openwebindex.eu/wp-content/uploads/2019/01/Open_Web_Index_proposal.pdf, abgerufen am 09. August 2019 Quelle Abbildung 1: Modularer Aufbau der Dienste des OWI [1] 1. Welche Arten der Priorisierung von Crawler-Warteschlangen gibt es? 4. Welche Vergleiche gibt es und wie erfolgt die Evaluation? 2. Gibt es Priorisierungstechniken explizit für verteilte Crawler? 3. Welche geotopologische Ansätze gibt es bereits? Abbildung 2: Forschungsfragen Tabelle 1: Phasen der Masterthesis Jul 20 Okt 19 Nov 19 Dez 19 Jan 20 Feb 20 Mrz 20 Start Abgabe Apr 20 Mai 20 Jun 20 Sep 19 4. Realisierung 5. Evaluation 6. Schriftl. Ausarbeitung 7. Projektmanagement 1. Analyse 3. Entwurf 2. Admin. Vorbereitung Puffer M3 M4 M5 M1 M2 OSS Abbildung 3: Zeitplanung der Masterthesis Abbildung 4: Verortung der Steuerun | poster |
OCL 2.0 Reference Card Author: Fernando Brito e Abreu (fba@iscte-iul.pt) Affiliation: ISTAR-IUL / ISCTE-IUL Collection type operations Set Bag OrderedSet Sequence Description collection->size(): Integer V V V V Number of elements in the self collection collection->isEmpty(): Boolean V V V V True if the self collection is empty collection->notEmpty(): Boolean V V V V True if the self collection is not empty collection1 = collection2 : Boolean V V V V True if the first collection is equal to the second collection collection1 <> collection2 : Boolean V V V V True if the first collection is different to the second collection collection->isUnique(expr: T): Boolean V V V V True if the argument expression is unique within the self collection collection->select(expr: Boolean): Collection(T) V V V V Elements of the self collection that match the argument condition collection->reject(expr: Boolean): Collection(T) V V V V Elements of the self collection that do not match the argument condition collection->sortedBy(OclBasicType): Sequence(T) V V V V Elements of the self collection sorted by the argument expression collection->collect(expr: T): Collection(T) V V V V Flattened collection of expression values obtained from the self collection members collection->collectNested(expr: T): Collection(T) V V V V Nested collection of expression values obtained from the self collection members collection->iterate(x:I [; acc:J=init]|expr: T|Collection(T)): T|Collection(T) V V V V Iterator that allows defining its logic collection->forAll(expr: Boolean): Boolean V V V V True if the argument expression holds for all members of the self collection collection->exists(expr: Boolean): Boolean V V V V True if the argument holds for at least one member of the self collection collection->one(expr: Boolean): Boolean V V V V True if the argument holds for only one member of the self collection collection->includes(element: T): Boolean V V V V True if the argument is part of the self collection collection->excludes(element: T): Boolean V V V V True if the argument is not part of the self collection collection->includesAll(collection: Collection(T)): Boolean V V V V True if all members of the argument collection belong to the self collection collection->excludesAll(collection: Collection(T)): Boolean V V V V True if none of the members of the argument collection belong to the self collection collection->including(element: T): Collection(T) V V V V The self collection with the argument added to it collection->excluding(element: T): Collection(T) V V V V The self collection with the argument removed from it collection->union(collection: Collection(T)): Collection(T) V V V V The union of the self collection with the argument collection collection->intersection(collection: Set(T) | Bag(T)): Set(T) | Bag(T) V V The intersection of the self collection with the argument collection collection1 - collection2: Set(T) V The first set excluding all elements of the second set collection->symmetricDifference(collection: Set(T)): Set(T) V Union of the self collection with the argument collection, minus their intersection collection->prepend(element: T): OrderedSet(T) | Sequence(T) V V The self (ordered) collection prepended with the argument collection->insertAt(pos:Integer,element:T):OrderedSet(T)|Sequence(T) V V The self (ordered) collection with the argument inserted at the position collection->reverse(): OrderedSet(T) | Sequence(T) V V The self (ordered) collection in reverse order collection->append(element: T): OrderedSet(T) | Sequence(T) V V The self (ordered) collection appended with the argument collection->flatten(): Collection(T) V V V V The self collection flattened; only produces effect if the self collection is nested collection->sum(): Integer | Real V V V V The addition of all elements of an Integer or Real collection collection->max(): Integer | Real V V V V The largest element of an Integer or Real collection collection->min(): Integer | Real V V V V The smal | poster |
Amphipods Crabs Barnacles Brine shrimp Copepods Amphipods Antennae Head Thorax Telson Abdomen They are considered "bees of the sea" for pollinating the seagrass flowers Design & illustration: Alberto Guerra Content consulting: María Muciño Carlos Paz In the world there are: and in Mexico: from the greek “amphi”: both sides of and “podos”: foot (Feet on both sides) Coordinación: Diana Ugalde and Nuno Simões ±10,000 species The largest is 29 cm The first 4 feet facing backward The last 3 feet facing forward They parasitize dolphins and whales Intertidal zone Beaches Buoys Seaweeds Boat hulls Sand or mud tubes Inside burrows live on the water bottom (marine or freshwater) Seagrasses Sea stars Sponges Tunicates Hydrozoans Vertical migration in the water column 1 mm You can find them in the deepest place on the earth: The Mariana Trench They live in: Crustaceans Gammarids Feeding: Caprellids Hyperiids Talitrids Cyamids 0 m ±11,000 m Are the prey of: they are essential in the food chains of fish, mollusks, and birds Some adhere to fish gills to get food. Seaweeds Detritivores and Scavengers Filter-feeders Herbivores ±950 species The female has a "ventral brood pouch" where the eggs develop. Female caprellids protect hatched juveniles on their bodies and gammarids in burrows. (skeleton shrimp) (sand fleas) Fish Shrimp Polychaetes and nemerteans worms They are the favorite food of seahorses! ♀ ♂ Life cycle Corales Corals | poster |
RESEARCH POSTER PRESENTATION DESIGN © 2015 www.PosterPresentations.com RAN2 Summary & Remaining Work 1. NOAA STAR, 2. GST Inc. Olafur Jonasson1,2, Alexander Ignatov1 ACSPO VIIRS SST Reanalysis 2 (RAN2) GHRSST XX Science Team Meeting, Frascati, Italy, June 3-7, 2019 olafur.jonasson@noaa.gov Acknowledgement. This work is supported by the NOAA JPSS program. Thank to M. Goldberg, L. Gumley, S. Dutcher, J. Stroup for setting up and conducting SNPP ACSPO RAN1. We thank our SST colleagues Y. Kihai, B. Petrenko, M. Pennybacker, I. Gladkova for help. We thank Edward Armstrong and Wen-Hao Li for assistance with archival at PO.DAAC. The views, opinions, and findings in this report are those of the authors and should not be construed as an official NOAA or U.S. government position or policy. Background & Objectives of VIIRS SST Reanalyses (RANs) • Suomi NPP launched 28 Oct 2011; Cryoradiator door opened 18 Jan 2012. • N20 (aka “J1”) launched 18 Nov 2017; Cryoradiator door opened 3 Jan 2018. • VIIRS SST produced 1-2 days after opening the cryoradiator doors using NOAA Advanced Clear Sky Processor for Ocean (ACSPO) enterprise system. • This poster summarizes SST Reanalysis 2 (RAN2), from NPP & N20. • L2P (swath) & L3U (0.02º; gridded) data reported in 10-min granules (144/day). • Regression (‘sub-skin’) SST & SSES (used to derive ‘depth’ SST) are reported. • Cal/Val is performed using match-ups with in situ data from NOAA in situ SST Quality Monitor (iQuam; www.star.nesdis.noaa.gov/sod/sst/iquam) • Quality Control and Cal/Val statistics are published in the NOAA SST Quality Analysis Monitor (SQUAM; www.star.nesdis.noaa.gov/sod/sst/squam) • ACSPO Regional Monitor for SST (www.star.nesdis.noaa.gov/sod/sst/arms/; ARMS) monitors regional performance of VIIRS SST imagery, and compares it with other polar AVHRR/MODIS and geostationary ABI/AHI SST products. • Monitoring IR Clear-sky Radiances (www.star.nesdis.noaa.gov/sod/sst/micros/; MICROS) compares measured brightness temperatures (BTs) in VIIRS SST bands to simulations using the Community Radiative Transfer Model (CRTM) • Data in GDS2 format archived in NASA PO.DAAC & NOAA CoastWatch/NCEI. VIIRS SST Reanalysis 1 (RAN1; NPP only) • RAN1 was performed in 2015 in conjunction with U. Wisconsin CSPP Team, using ACSPO v2.40, and covered a period from Mar’2012-Dec’2015. Period from Dec’2015-on was supplemented from NRT processing (ACSPO v2.41/2.60/2.61). • Results of NPP RAN1 are available on the NOAA CW website. Its monitoring was included in SQUAM and MICROS. • Fig. 1 show results of validation of RAN1 ‘sub-skin’ and ‘depth’ L2P SSTs vs. iQuam in situ SSTs (drifters + tropical moorings). Each point represents 24hr global statistics. Statistics for the full period are summarized in Table 1. • Global mean biases ‘Sub-skin minus in situ SST’ and ‘Depth minus in situ SST’ in Figs. 1a-b are fairly stable in time, with residual seasonal variations up to ~0.1 K (more during the daytime, likely due to increased skin-depth SST difference). • The standard deviations are larger for ‘sub-skin’ SST (Fig. 1c), especially during the daytime, due to increased skin-depth differences. The standard deviations and day-night differences, are reduced for ‘depth’ SST (shown in Fig. 1d). Figure 1. Daily statistics of global (a-b) mean biases and (c-d) standard deviations (SDs) of ACSPO L2P minus iQuam SSTs. From mid-Dec’2015 – Apr’2019, NPP RAN1 (Mar’2012 – mid-Dec’2015) is supplemented by operational data. (Left) Global Regression (GR; proxy for ‘sub-skin’ SST); (right) Piece-Wise Regression (PWR; proxy for ‘depth’ SST). RAN1 (NPP) L2P (‘sub-skin’) L3U (‘sub-skin’) L2P (‘depth’) L3U (‘depth’) Bias (night) [K] +0.029 +0.045 +0.012 +0.017 Bias (day) [K] +0.014 +0.009 +0.032 +0.027 SD (night) [K] 0.32 0.32 0.27 0.27 SD (day) [K] 0.39 0.39 0.30 0.30 Table 1: NPP VIIRS RAN1 SST biases and standard deviations (SD) from 1 Mar 2012 – 30 Apr 2019. “L2P ‘sub-skin’ minus in situ” statistics are from Fig. 1a,c and “L2P ‘depth’ minus | poster |
Bringing the Grey Literature Out of the Shadows: The Demise of a Technical Report Database Silo Willow Dressel, Engineering and Plasma Physics Librarian, Princeton University Introduction The Library at the Princeton Plasma Physics Laboratory (PPPL) started in the 1950s in the early years of the lab. In the beginning, the collection primarily consisted of theoretical papers in the form of either technical reports or journal articles. In the 1960s the first librarian, Elizabeth “Betty” Graydon, was hired. Betty, assisted by summer students, built a card catalog of the holdings of the library. * The card catalog was not just a record of the library’s holdings, but a local index of the literature in plasma physics and controlled fusion. Being one of the only Department of Energy laboratories solely devoted to research in Plasma Physics and Controlled Fusion, the library has always attempted to maintain as complete a collection of relevant literature as possible. Materials collected by the library were largely in the form of technical reports and journal articles. Incoming journals were thoroughly examined and card catalog records created for individual articles as well as technical reports and other materials. The Plasma Physics Library Catalog (PPLCat) was started on July 1, 1986 to continue to provide bibliographic citations to the library’s technical reports, journal articles, and conference proceedings. The back catalog of technical reports produced by PPPL was added to PPLCat. Although the library had access to the Energy Citations Database through Dialog, librarians felt it was important to maintain the tradition of having a local index of the literature. Monographs, journal holdings, and similar materials were now a part of Princeton University Library’s online GEAC catalog.* Around 2000, PPLCat was moved to a Microsoft Access database and a web interface was created bringing the collection online and making it more visible. A sample record from PPLCat. An aging database. By 2005 the only materials being added to PPLCat were the technical reports received in print at the library. Proprietary and public databases had become more reliable, timely, and comprehensive gateways in to the literature and individual journal articles had reached a critical mass where maintaining a local database was too cumbersome. At the same time many laboratories in the field stopped the expensive process of mailing print copies of reports and began posting digital copies online, including PPPL itself. As of 2005, all new PPPL technical reports were made available on the lab’s website. *“History of the Plasma Physics Library: Growth by Decade (1960-current)”, n.d. http://www.pppl.gov/library/History/history.html. Abstract At the Furth Library in the Princeton Plasma Physics Laboratory (PPPL), staff have been using a Microsoft Access database called PPLCat to keep track of a variety of materials held in the library including technical reports and journal articles since 1985. The database has grown outdated, is slow to use, and has limited functionality compared to newer publicly available databases. Working with librarians from the Library Systems and Cataloging departments, a project was developed to identify and transfer relevant records from PPLCat into Princeton’s main library catalog. In 2009 the Access database was starting to show its age. Little new material was being added and many of the advanced search features of the web interface no longer worked. It went from being a valued local bibliographic database, to a separate inventory of technical reports holdings. As the library started to look at new discovery systems, these types of local inventories began to be seen as unnecessary silos of information. In addition, the programmer who designed PPLCat was retiring and his replacement would not be expected to support the database after he was gone. Transferring records to the Main Catalog: XML to the rescue Thanks to XML, PPLCat records cou | poster |
THE YEDOMA CLIFF OF SOBO‑SISE ISLAND ‑ INSIGHTS INTO PAST AND MODERN PERMAFROST DYNAMICS AND RELATED ORGANIC MATTER STOCK AND RELEASE Afiliations * Alfred Wegener Institute Helmholtz Centre of Polar and Marine Research, Potsdam, Germany ** Faculty of Geography, Lomonosov Moscow State University, Moscow, Russia *** Polar Geography, Arctic and Antarctic Research Institute, St. Petersburg, Russia References Fuchs et al. Rapid )luvio‐thermal erosion of a yedoma permafrost cliff in the Lena River Delta, Front. Earth Sci., 2020, 8, 336. Margold et al. Repeated mega)loods from glacial Lake Vitim, Siberia, to the Arctic Ocean over the past 60,000 years, Quaternary Sci. Rev., 2018, 187, 41‐61. Wetterich et al. The cryostratigraphy of the Yedoma cliff of Sobo‐Sise Island (Lena Delta) reveals permafrost dynamics in the Central Laptev Sea coastal region during the last about 52 ka. TCD, under review, https://doi.org/10.5194/tc‐2020‐179. Figure 1. Profile positions of sediment profiles SOB18‐01, SOB18‐03 and SOB18‐06 as well as ice‐wedge profiles in 2014 and 2018. Lena Delta inset from ESA‐BELSPO 2015, produced by VITO (ESA Earth online). Yedoma (MIS3) 1 The Sobo‑Sise Yedoma Cliff Syngenetic late Pleistocene Ice Complex of the Yedoma type is widespread in East Siberian lowlands and intentively studied in the Lena Delta and the Laptev Sea coastal in recent decades by joint Russian‑German efforts (LENA Expedition). Diagnostic for Yedoma Ice Complex are the presence of syngenetic ice wedges, the oversaturation of the sediment with pore ice and segregated ice (excess ice) forming lenticular and reticulate cryostructures within mainly )ine‐grained deposits. During a )ield campaign in 2018, the entire permafrost sequence of the Sobo‑Sise Yedoma cliff has been sampled in 0.5‐m vertical intervals via rope decending in three overlapping pro)iles (Wetterich et al., 2020; Figure 1). The studied Yedoma cliff on Sobo‐Sise Island is remarkable for its rapid shoreline erosion of up to 22.3 m yr⁻¹ (1965‐2018; Fuchs et al., 2020) over about 1.9 km length with a mean annual retreat rate of 9.1 m yr⁻¹. The present study of the permafrost exposed the Sobo‐Sise Yedoma cliff provides a comprehensive cryostratigraphic and organic matter inventory, insights into permafrost aggradation and degradation over the last about 52 thousand years and their climatic and morphodynamic controls on regional scale of the Central Laptev Sea coastal region in NE Siberia. Sebastian Wetterich*, Matthias Fuchs*, Alexander Kizyakov**, Jens Strauss*, Ingmar Nitze*, Michael Fritz*, Juliane Wolter*, Thomas Opel*, Hanno Meyer*, Aleksei Aksenov***, Lutz Schirrmeister*, Guido Grosse* 2 Geochronology and cryostratigraphy The geochronological record of the Sobo Sise Yedoma spans the last 52 ka cal BP based on radiocarbon dating and age‐height modelling (Figures 2, 3). The sequence differentiates into three cryostratigraphic units that are MIS 3 Yedoma IC (52–28 ka cal BP), MIS 2 Yedoma IC (28–15 ka cal BP) and MIS 1 Holocene cover (7–0 ka cal BP). The cryostratigraphic sequence is not continuous, but has chronological gaps at 36–29 ka cal BP, at 20–17 ka cal BP and at 15–7 cal ka BP (Figure 2). These gaps represent traces of past changes in climatic conditions as well as in permafrost deposition and/or erosion regimes. Similar observations have been made on adjacent Yedoma IC sites on Bykovsky Peninsula and Kurungnakh‐Sise Island (Figure 4) and are likely related to repeated outburst )loods of glacial Lake Vitim along the Lena Valley into the Arctic Ocean during MIS 3 and MIS 2 as proposed by Margold et al. (2018). The cryostratigraphic units of the Yedoma cliff are built of poorly sorted sandy silt but differ in prevalent grain‐size fractions ranging from )ine silt to middle sand. The organic matter content is highest in the thin MIS 1 (unit C) Holocene cover (TOC of 11.3±9.9 wt%, TN of 0.6±0.3 wt%), but still substantial in MIS 3 (unit A) Yedoma IC (TOC of 4.5±2.5 wt%, TN of 0.3±0.1 wt%) and in MI | poster |
Label-free quantification is an important mass spectrometry method that requires no specific sample labeling. Instead, it utilized MS/MS generated signals of specific peptides for comparison to define protein expression modifications between samples. Two alternative label-free quantification strategies are frequently used, Spectra Count (SC) and peptide ion intensities measurements (a.k.a., XIC, extracted ion chromatography), with the latter being more accurate and widely used. Label-free quantification requires highly stable and reproducible liquid chromatography with tandem mass spectrometry (LC-MS-MS) and has no requirement for expensive isotopes for labeling. Label-free based quantitative proteomic analysis can be applied to analyze almost all regular biological samples (cells, tissues, biofluids, feces, plant samples, etc.), especially for large quantity sample comparison. Tel: 1-631-275-3058 (USA) Fax: 1-631-614-7828 Email: info@creative-proteomics.com Label-Free Quantification Disease biomarker research Drug efficacy evaluation Plant growth and development research Plant disease resistance and insect resistance research Microbial stress and adversity physiology research Food component and quality identification Environmental risk assessment Special behavior mechanism and food/medicinal value research Application Areas | poster |
Contact: Confidential This work is supported by: AN INTERFACE WITH COMPUTER-GENERATED FACIAL EXPRESSIONS AS AN ALTERNATIVE FOR MOOD SELF-REPORTS IN AN EMA CONTEXT Hristo Valev[a,b], Tim Leufkens[a], Joyce Westerink[a,c], Corina Sas[b] Philips Research [a] Lancaster University [b] Technical University Eindhoven [c] hristo.valev@philips.com h.valev@lancaster.ac.uk Abstract Traditionally numerical scales, colors, abstract representations or animated characters have been for reporting one’s own mood. While working in practice, they do not provide a universal stable representation between participants. Abstract representations or colors rely on subjective interpretation, while numerical or animated characters require mapping the subjective feeling of mood onto a scale, which is also differentially interpretable. The described approach relies on computer-generated facial expressions to span a scale, which can be used for mood self-reports. Generating facial expressions [1] O. Langner, R. Dotsch, G. Bijlstra, D. H. J. Wigboldus, S. T. Hawk, and A. van Knippenberg, “Presentation and validation of the radboud faces database,” Cogn. Emot., vol. 24, no. 8, pp. 1377–1388, 2010. Participants 37 healthy participants in the Netherlands (20 male and 17 female) with an mean age of 30 years old were recruited. All participants provided an informed consent form prior to their recruitment. Relationship between type of assessment, oscillations and assessment duration On the left hand side you see all participants (N=37) that took part in the study. The amount of assessments is represented by the thickness of the lines. Each provided assessment with the facial expression interface and the slider is depicted in the first band. For each assessment we captured the ‘oscillations’ or turning points in the pattern of their selection, represented in the second band. The final band depicts the time it took to provide an assessment, where the label describes the higher bound of the duration except for the highest value. Graph has been generated with raw-graphs ("How to make an alluvial diagram", by RAWGraphs Team. Licensed under CC BY-NC-SA 4.0. Accessed: May 12, 2020, from https://rawgraphs.io/learning/how-to-make-an-alluvial-diagram/) Results This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska- Curie grant agreement No 722022. Discussion • We have recruited healthy participants, which is why as expected the distribution is heavily represented in the happiness dimension. This may have unforeseen implications for sadness. • The high correlation between both assessments gives us the insight that both assessment methods can be used interchangeably with high certainty that they will yield comparative results. • Albeit not conclusive, the significantly higher variance captured by the facial expression interface could mean that it describes better the modality of mood. Furthermore, two-thirds of the assessments provided with the facial expression interface featured more than one turning points in their trace. This is indicative of the desire of the participants to be more particular in their input. • The quality of the generated facial expressions was good as they were easily understood, even though the only real facial expressions used to train the model were the expressions for extreme happiness (i.e. 200), extreme sadness (i.e. 0) and the neutral expression. Considerations • The happiest or saddest facial expressions might not necessarily be representative of their respective extremes, which could explain the offset between the distributions for the facial expression and slider assessments. • Timestamps were only recorded during the interaction with the assessment elements. This might have reduced the time required to provide an assessment with the slider as a single tap would have a 0 seconds duration. AffecTech: Personal Technologies for Affective Health Distribution plot of a | poster |
Faraday Rotation Spectroscopy (FRS): What is it? Hybrid-FRS: high-sensitivity detection of O2 for environmental sensing Eric J. Zhang, Brian E. Brumfield, Gerard Wysocki* Dept. of Electrical Engineering, Princeton University, Princeton N.J. 08544 *email: gwysocki@princeton.edu Summary We present a hybrid-FRS technique combining laser-noise cancellation with signal-to-noise optimization for near- shot noise limited performance. Highly- sensitive O2 detection is demonstrated using < 5 W power for low-power field deployable operation. • Present chemical O2 sensing systems do not combine high- sensitivity, robustness and low-power usage compared to optical sensing methods • Monitor changes in O2 with < 1 ppmv/√Hz for biotic respiration and combustion monitoring • Low-power Faraday rotation spectroscopy (FRS) based gas sensors for paramagnetic molecule detection (e.g. O2, NO, OH, NO2, etc.). • Magnetic field Circular birefringence Polarization rotation • Analyzer converts polarization rotation into intensity change • ~ 100ൈimprovement over direct absorption spectroscopy w/ dynamic range > 105. Absorption Spectrum Dispersion Spectrum Experiment • O2 detection in near-infrared (762 nm); techniques developed are applicable to other paramagnetic species. • DC-magnetic field for zero-power field generation • Variable attenuator allows simultaneous use of 45° and 90° methods • Attenuate reference beam without reducing FRS signal • Operating point: α ≈8°, 50:1 ref:sig split ratio. 90° method vs. 45° method • Two implementations of FRS: (i) 90° method / angle optimization, (ii) 45° method / balanced detection O2 Detection Limits Benefits of Hybrid-FRS Future Directions Conclusions Acknowledgements The authors would like to acknowledge the NSF-ERC MIRTHE Center and Lynn and Thomas Ou for their generous contribution. Professor Mark Zondlo and Kang Sun assisted with the multi-pass cell construction. • Hybrid-FRS is a superset of 90°-method + 45°-method • O2 detection limit: 0.6 ppmv @ 1-sec., 1.4x shot-noise limit • Power consumption: < 5 W using permanent magnets • Laser power optimization can provide up to 3x sensitivity enhancement. • When P0,min < 1.1 mW, the 45° method provides greatest sensitivity • When P0,max > 1 W, SNR degrades due to ‘leaky’ polarizers • Hybrid-FRS utilizes both noise cancellation and SNR optimization. • Detector saturation limit is removed due to constant signal beam power (excess power not contributing to the FRS signal is dumped using attenuator). Motivation • Line of constant Psig does not intersect with detector saturation curve • Three methods of SNR enhancement: (i) line of constant α (balanced detection) (ii) line of constant P0 (angle optimization) (iii) line of constant Psig (hybrid-FRS) • For increasing power, (i) balanced detection and (iii) hybrid- FRS give the same SNR ~ ܲenhancement. • Balanced detection limited by detector saturation, hybrid- FRS limited by laser power! | poster |
Sam Pepler/STFC NCAS conference demo, 2008, Bristol Overlay Journals Sam Pepler Science and Technology Facilities Council STFC The OJIMS project is investigating the idea of data publication in the atmospheric sciences. It is creating the required mechanics for overlay journals and examine their long term sustainability. The project will also set up a document repository for the atmospheric sciences. This would preserve a range of documents relevant to atmospheric science including journal papers, technical reports, and images. Overlay Journal Infrastructure for Meteorological Sciences (OJIMS) The project partners are the Royal Meteorological Society and The National Centre for Atmospheric Science (NCAS). The OJIMS project is funded by NERC and JISC http://proj.badc.rl.ac.uk/ojims A Journal (Any online journal system) PDF PDF PDF PDFPDF Word with journal template 1) Author prepares the paper using word processing software. 3) Reviewer reviews the PDF file against the journal’s acceptance criteria. 2) Author submits the paper as a PDF file. Traditional online journal model BADC Data Data BODC Data Data Pangaea Data MetData (Using Open Journal System) xml xml xml xml xml Overlay editor with journal configuration 1) Author prepares the overlay XML document using the web editor.. 2) Author submits the dataset as an XML file. 3) Reviewer reviews the XML file and the dataset it points to against the journal’s acceptance criteria. Overlay journal model for publishing data Potential benefits of a Data Journal to the UK met community: •Extend the value of peer-review from papers to data, to provide assurance that data documentation meets the necessary scientific standards. •Provide an overview of the quality and applications of data, enabling it to be used more easily and appropriately in research and applications. •Provide recognition for the work of collecting and describing data. •Raise awareness of the meteorological datasets available to UK and international community. | poster |
Fred Hänel 0000-0002-3385-3267 Technische Hochschule Ingolstadt - Bibliothek Bibliothek FDM-Services der Hochschulbibliothek der TH Ingolstadt: Ohne Nachnutzung und Vernetzung geht es nicht Angebot: Informationen auf der Website der Bibliothek Ziel: Bereitstellung grundlegender Informationen zum FDM an einer Stelle als kompakter Überblick Nachnutzung öffentlich zugänglicher Informationsangebote, z. B. forschungsdaten.info, DFG, GO FAIR, forschungsdaten.org Verweis auf genutzte Quellen für weitere, vertiefte Informationen Angebot: Individuelle Beratung auf Anfrage Ziel: Unterstützung bei konkreten Bedarfen, z. B. Projektanträge (DMP) und Daten-Veröffentlichung / Repositorien-Suche spezifische Beratung nach individuellen Bedarfen Vermittlung öffentlich zugänglicher Tools, z. B. offene RDMO-Instanz von forschungsdaten.info, re3data Angebot: Schulungen Ziel: Vermittlung von Kenntnissen über FDM insgesamt, Teilbereiche und spezielle Tools Bereitstellung von Selbstlernkursen, Videos und Quizzes aus öffentlich zugänglichen Quellen im Aufbau: eigenes Angebot an Kurzschulungen („Coffee Lectures“), auch unter Nachnutzung von OER Angebot: Tools Ziel: Bereitstellung einer (grundlegenden) technischen Infrastruktur Verweis auf öffentliche und hochschuleigene Tools und Infrastrukturen z. B. DataCite Metadaten Generator, FAU-Box Maßnahme: Vernetzung Ziel: Erfahrungsaustausch mit anderen Expertinnen und Experten Teilnahme an Netzwerken wie „rdmuc – Münchner Arbeitskreis für Forschungsdaten“ und „FDM-Kompetenzpool des Bayerischen Bibliotheksverbunds“ verstärkter Ausbau: interne Vernetzung an der eigenen Hochschule Maßnahme: Aktuelle Entwicklungen verfolgen Ziel: Kenntnisse und Wissen aktuell halten Abonnements von Newslettern, Teilnahme an Mailing-Listen z. B. RfII Infoticker, FDM-Bayern Maßnahme: Kontinuierliche Weiterentwicklung Ziel: Bereitstellung eines umfassenden Angebots entlang des Forschungsdaten-Lebenszyklus Erweiterung des Informationsangebots, Ausbau der Schulungsaktivitäten, Kompetenzausbau im Team, Bereitstellung Infrastruktur z. B. Community bei Zenodo, Nachweis von Forschungsdaten im Repository der Hochschule Die Inhalte dieses Posters (ausgenommen Logos, Markenzeichen, Fonts) sind unter CC BY 4.0 lizenziert. | poster |
The recruitment and retention of high quality teachers is one of central tenets of many education systems around the world. Some of the strategies used by many countries to maintain their stock of high-quality teachers include better monetary compensation, continuing professional development, leadership training, and also performance based increases in pay. However, many countries – especially those in the developing world – continue to face shortages of high quality secondary education teachers in several critical areas including science and mathematics (1). An additional approach that developing countries must use to attract the most talented science students into the teaching profession is to employ more media campaigns across TV, radio, and also the web. Such campaigns must show how important science teachers are for the future, and the important place they occupy next to other respected professions in society. Overtime, such active exposure will help (a) inspire more young students to start thinking early about a career in science education and (b) highlight the importance of science teachers in society which will in turn help slowly elevate the status of science teachers across all education levels. The success of the media campaigns will require coordination between schools, academic institutions, non-governmental agencies, foundations, and also the federal government to ensure the message is consistent. Of course, no single strategy is sufficient by itself as a number of factors govern the sufficient recruitment and retention of high quality science teachers. Media campaigns should be used as one part of a wider strategy in tackling science teacher shortage. Education: Using media to promote K-12 science teachers 1. UNESCO, Wanted: Trained teachers to ensure every child’s right to primary education. POLICY Pap. 15 / FACT SHEET 30 (2014), (available at http://www.uis.unesco.org/Library/Documents/fs30- trained-teachers-to-ensure-right-to-primary-education-en.pdf). References G|M Advocacy Group Fanuel Muindi, PhD GM Advocacy Group, Boston MA Abstract | poster |
Il contributo offre una panoramica degli strumenti informatici e della loro applicazione nella realizzazione di materiale didattico semplificato e facilitato. Grazie all’aumentata interattività, che permette allo studente di apprendere in un ambiente dinamico, sono numerose le potenzialità che le varie figure educative possono sfruttare padroneggiando le tecnologie. Di seguito viene proposta una classificazione delle tecnologie in base al loro utilizzo in tale ambito. Le tre casistiche proposte sono corredate da altrettanti esempi applicativi, con l’obiettivo di fornire al docente spunti metodologici per pianificare una didattica inclusiva attraverso l’utilizzo delle tecnologie. CASO B 1 Liceo Scientifico “P.Levi” 2 Saint Camillus International University Maria Chiara Mattacchione1, Luca Del Greco2 Tecnologie digitali per la realizzazione e adattamento di contenuti scolastici facilitati e semplificati CASO A CLASSIFICAZIONE • Caso a Il docente si avvale degli strumenti digitali per realizzare contenuti da presentare all'allievo, prevedendo la realizzazione di materiale semplificato e facilitato o di strumenti facilitanti. In questo caso lo strumento digitale è funzionale al lavoro di predisposizione del materiale didattico adattato e pertanto non è direttamente proposto allo studente; • Caso b L’alunno utilizza, in autonomia o supportato da una figura adulta, gli strumenti digitali. Tali strumenti possono essere utilizzati dallo studente per costruire supporti didattici attraverso i quali focalizzare meglio un argomento studiato in classe o supportare l’esposizione orale nel momento della verifica. In questo caso lo strumento digitale è di ausilio allo studio individuale dell’alunno. La tecnologia è funzionale alla predisposizione del materiale ed è utilizzata direttamente dell’alunno; • Caso c Il docente propone all’allievo attività su piattaforme digitali, quali, ad esempio, quiz per la verifica degli apprendimenti, piattaforme di condivisione dei contenuti e ulteriori stimoli interattivi. In questo caso non viene realizzato alcun prodotto, ma è lo stesso strumento digitale a fungere da ausilio allo studio individuale dell’alunno. CONCLUSIONI • Con il presente contributo si è voluto proporre una tassonomia in grado di classificare i diversi utilizzi delle tecnologie in ambito didattico, distinguendo tre categorie specifiche, corredate da altrettanti esempi esplicativi. • I contenuti mostrati negli esempi non sono comprensivi dell’intero panorama disponibile, ma consentono di evidenziare le differenze tra le categorie proposte. • Tale classificazione può essere d’aiuto per i docenti, al fine di renderli maggiormente consapevoli circa la possibilità di applicazione dei vari strumenti all’interno del contesto scolastico, sia per gli sviluppatori che possono in tal modo orientare lo sviluppo dei software anche in funzione delle esigenze della comunità scolastica. Docente Materiale adattato Alunno Materiale adattato Alunno Docente Attività in digitale Docente Alunno CASO C ESEMPI STORYBOARD THAT CANVA KAHOOT FUMETTO FLASH-CARD QUIZ INTRODUZIONE | poster |
OPEN ACCESS Lizenziert unter CC BY 4.0 | https://creativecommons.org/licenses/by/4.0 Erstellt an der TU Berlin BY VORTEILE UND HERAUSFORDERUNGEN Finanzen Traditionell wird der Zugang zu Zeitschriften über teure Abonnements gesichert. Nur wer sich die Lizenz leisten kann, hat Zugriff auf die Inhalte. Im Open Access sind Artikel für jedermann frei im Internet verfügbar. Sichtbarkeit & Verfügbarkeit Die freie Verfügbarkeit erhöht die weltweite Sichtbarkeit der Forschungsleistungen. Freiheit Verzicht auf Übertragung von Exklusivrechten an Verlage stärkt Rechte der Autorinnen und Autoren. Qualität Frei zugängliche Publikationen können von jedermann uneingeschränkt überprüft werden. Impact Open-Access-Publikationen werden häufiger zitiert. Remix Neue Ausgaben, Modifikationen, Übersetzungen werden erleichtert, da für Open-Access-Inhalte meist freie Creative-Commons-Lizenzen verwendet werden. Kosten Auch Open Access kostet Geld. Zeitschriften finanzieren sich häufig über Publikationsgebühren. Geschäftsmodelle und etablierte Abläufe müssen angepasst werden. Langzeitarchivierung Digitale Publikationen sollen auch digital archiviert werden. Technische Lösungen sind in der Entwicklung. Nachnutzbarkeit Eine konsequente Vergabe freier Creative- Commons-Lizenzen ist erforderlich, um eine einfache Nutzung von Werken zu ermöglichen. Qualitätskontrolle Erkennen unseriöser Verlage. Open-Access-Infrastruktur Freier Zugang und Nachnutzbarkeit sind als Standard in allen Prozessen zu verankern. VORTEILE HERAUSFORDERUNGEN Mit öffentlichen Mitteln finanzierte Forschungsergebnisse sollten öffentlich zugänglich sein. Open Access beschreibt das Ziel, wissenschaftliche Informationen frei im Internet zugänglich zu machen, so dass Interessierte die Volltexte lesen, herunterladen, kopieren, verteilen, drucken, in ihnen suchen, auf sie verweisen und sie auch sonst auf jede denkbare legale Weise benutzen können. Einzige Bedingung ist stets die korrekte Nennung der Urheberschaft. | poster |
OPEN REPOSITORIES AND SUSTAINABLE DEVELOPMENT GOALS: BRIDGING THE INFORMATION GAP MPUNDU CHILONGA KWAME NKRUMAH UNIVERSITY - ZAMBIA 1. Introduction SUSTAINABLE DEVELOPMENT GOALS 5. Notable Open Repositories This is an exploratory study of the important role which Open Repositories in Zambia can play to support The Sustainable Development Goals (SDGs), established by the United Nations in 2015 as part of the 2030 Agenda for Sustainable Development. The aim of the SDGs to address the most pressing global challenges, including poverty, inequality, climate change, environmental degradation, education, health, and peace and justice. They require a collaborative and collective action from governments, civil society, private sector, academia, and individuals worldwide.to ensure that no one is left behind in the pursuit of development. By aligning policies, investments, and actions with the SDGs, we can strive towards a more sustainable and resilient future for present and future generations. 2 In Zambia, Open Repositories are relatively a new phenomenon, and only a limited number of them are found, particularly in Public Universities. ORs Specifically designed to support the Sustainable Development Goals (SDGs): Climate Data Store (CDS): https://cds.climate.copernicus.eu/ Data.gov: Website: https://www.data.gov/ Global Open Data for Agriculture and Nutrition (GODAN): https://www.godan.info/ OpenSDG: https://open-sdg.org/ SDG Knowledge Hub: https://sdg.iisd.org/ SDG Tracker: https://sdg-tracker.org/ UN Data: http://data.un.org/ 6. Benefits of Open Repositories for SDGs The benefits of open repositories in supporting global efforts towards sustainable development: • Accessibility and Open Access, • Knowledge Sharing and Collaboration, • Data Sharing and Transparency, • Reproducibility and Rigor, • Capacity Building and Learning, • Innovation and Collaboration Beyond Boundaries, • Global Knowledge Exchange, • Monitoring and evaluation 3. Open Repositories and Achieving the SDGs Contributions of open repositories to the achievement of the SDGs: Accessible Knowledge: Making relevant knowledge easily accessible to stakeholders. Knowledge Sharing and Collaboration: Fostering a culture of collaboration and cross-sectoral sharing. Capacity Building and Learning: Providing resources for acquiring skills and knowledge. Evidence-Based Decision-Making: Supporting policy-makers with reliable and up-to-date information. Innovation and Technology Transfer: Promoting the sharing of innovative solutions. Monitoring and Evaluation: Providing a transparent platform for tracking progress. 2. Importance of Open Repositories 7. Challenges and Future Directions The key aspects of open repositories in supporting the SDGs: Collaboration: Bringing diverse stakeholders together to foster interdisciplinary collaboration. Data Sharing: Facilitating the sharing of research data, reports, and relevant datasets. Open Access to Information: Providing free and open access to SDG-related resources. Knowledge Dissemination: Acting as a centralised hub for collecting, organizing, and disseminating knowledge. Capacity Building: Offering learning resources and training materials for SDG- related skills development. Monitoring and Evaluation: Supporting progress tracking and data-informed decision-making. The challenges faced by Zambian ORs that may hinder future directions for their development include: Data Quality and Standardisation, Data Privacy and Ethics Capacity Building and Awareness Interoperability and Integration with Existing Systems, User Engagement and Collaboration, Sustainability and Long-term Support. 4. Key Features of Open Repositories for SDGs The essential features that open repositories should possess to effectively support the SDGs: Open Licensing, Metadata Standards, Version Control, Search Functionalities, Interoperability, User Engagement, Data Management Tools, Accessibility and Usabil | poster |
Non-Cognitive Predictors of Student Success: A Predictive Validity Comparison Between Domestic and International Students Focusing on the future impacts of current scientific research may increase students’ self-efficacy in science. Non-Cognitive Predictors of Student Success: A Predictive Validity Comparison Between Domestic and International Students TEACHING & LEARNING ISSUE: MOTIVATION Student attitudes, particularly the motivation to learn, play a significant role in student achievement in science courses. 1,2 Positively influencing student motivation to learn science, thus, is a route to improving student outcomes in science courses. Studies based in Social Cognitive Theory suggest that the temporal focus of a situation—its relation to the past, present or future—can affect motivation 3, yet no investigations of temporal focus within science classrooms have been reported. RESEARCH QUESTION Does the temporal focus of a classroom discussion impact students’ motivation to learn science? Hypothesis: Focusing discussion problems on the future impacts of scientific research will increase student motivation to learn science. METHODS 50 high school students over 2 years self-sorted into 4 sections of a 50-minute discussion course during a voluntary enrichment program. Questions from the Science Motivation Questionnaire II 4, a previously validated measure of student motivation to learn science, assessed outcomes. KEY RESULTS • Statistically significant (p < .0005) increase in self-efficacy for individuals in the future- focused discussion sections. • Students prefer to learn about current scientific research. REFLECTION Quick one-time interventions are valuable and can yield statistically significant improvements to student outcomes. Further investigation of temporal focus within the science classroom is encouraged. ADDITIONAL INFORMATION Motivation to learn science: “an internal state that arouses, directs, and sustains science- learning behavior.”4 SMQII Question Examples: Lecture Information: Students were introduced to historic examples of the impacts of research on society through machine learning as it relates to Netflix recommendations. The areas of scientific impact were then presented. This introduced students to the real-world consequences of scientific research and demonstrated a framework for evaluating the broader impacts of research. Insignificant Results: There were no significant changes measured for 4 factors of motivation (intrinsic motivation, career motivation, self- determination, and grade motivation). Students indicate that they prefer to learn about current scientific research PRESENTER: James Schwabacher The temporal focus of a discussion question may impact students’ motivation to learn science James C. Schwabacher @jschwabacher 0 2 4 6 8 10 12 14 16 18 -2 -1 0 1 2 Number of students Change in self-efficacy measure Intervention A Intervention B 0 4 8 12 16 20 1 2 3 4 5 Number of responses Self-efficacy measure Student responses to a measure of self-efficacy for pre- and post-interventions pre-A post-A pre-B post-B Pre-class survey Brief lecture Intervention A Intervention B Post-class survey Intervention A: Past-focused Intervention B: Future-focused 0 2 4 6 8 10 12 Strongly Prefer Past Slightly Prefer Past No Preference Slightly Prefer Current Strongly Prefer Current Number of responses Intervention A Intervention B REFERENCES (1) Reardon, R. F. et al. Discovering the Determinants of Chemistry Course Perceptions in Undergraduate Students. J. Chem. Educ. 2010. (2) Smist, J. M. General Chemistry and Self-Efficacy. Natl. Meet. Am. Chem. Soc. 1993 . (3) Karniol, R.; Ross, M. THE MOTIVATIONAL IMPACT OF TEMPORAL FOCUS: Thinking About the Future and the Past. Annu. Rev. Psychol. 1996. (4) Glynn, S. M. et al. Science Motivation Questionnaire II: Validation with Science Majors and Nonscience Majors. J. Res. Sci. Teach. 2011. Wilcoxon signed-rank test between pre- and post-intervention B scores for individuals i | poster |
Luminosity measurements at the Large Hadron electron Collider (and FCC-eh) K. Piotrzkowski and M. Przybycień AGH University of Science and Technology – Kraków The beam-size effect (BSE) was discovered at the VEPP-2 collider and later observed at HERA but remained ever since an elusive and poorly studied phenomenon, despite its impact on the electron and positron beam lifetimes at LEP and KEKB, for example. At the LHeC and FCC-eh, due to very small beam-sizes, this effect will be much stronger than at HERA and its understanding is essential for a precise determination of the luminosity at these electron-hadron colliders, using bremsstrahlung. Rate = L s ? Ee E′ e Eγ Q2 Ep E′ p e + p →e’ + g + p’ unique signatures it is kinematically allowed that qg = qe’ = qp’ = 0 hence there is no transfer of transverse momentum, which results in (for LAB variables): |q|min = me2 mp Eg /(4 Ep Ee E’e), where Q2 = -q2 ≈-q2min + qT2 For example, at the LHeC, for Ee = 50 GeV, Ep = 7000 GeV and Eg = 1 GeV, one gets the minimal longitudinal momentum transfer, in the proton rest-frame, Dpz = |qmin|/c = 0.00001 eV/c. The corresponding (kinetic) energy transfer = (Dp)2/2M ≈6.10-20 eV! From the uncertainty principle Dpz corresponds to the longitudinal distance ≈ℏ/Dpz of 21 mm whereas in the transverse plane the impact parameters is often even larger, as qT is often smaller than |q|min: d4s/dEg dqedqg df ∝Q-4 Higher beam energies/lower photon energy ⇒more extreme it becomes! Beam-Size Effect – effective bremsstrahlung suppression at high energies due to small lateral beam-sizes of both colliding beams: Event rate = Luminosity × cross section where colliding particles are represented by PLANE waves – and this assumption breaks down if the lateral beam sizes are comparable to typical impact parameters of a process. Using Van der Meer scans: Longitudinal view Transverse view We proposed a novel powerful test of the BSE by measuring the bremsstrahlung spectrum while displacing transversally a hadron beam. This will be at the same time a unique direct study/demonstration of long-range nature of bremsstrahlung process – for such lateral beam displacements we predict a strong effective increase of its cross-section! BSE calculations were made following Kotkin, Serbo & Schiller, Int. J. Mod. Phys. A 7, 4707 (1992) ⇐ 3 - 10 2 - 10 1 - 10 1 y 0 0.05 0.1 0.15 0.2 0.25 0.3 0.35 0.4 /dy) BH s /dy) / (d corr s (d EIC 1 EIC 2 = 10 GeV e E 18 GeV = 275 GeV p E 275 GeV m µ = 93 x s m µ 50 m µ = 7.8 y s m µ 5 HERA = 30 GeV e E = 820 GeV p E m µ = 290 x s m µ = 77 p y s m µ = 65 e y s LHeC = 50 GeV e E = 7000 GeV p E m µ = 5 x s m µ = 5 y s At the LHeC and FCC-eh the bremsstrahlung spectrum will be strongly suppressed over the entire range of photon energies! Both the beam sizes as well as beam alignment will have to be very well controlled. https://journals.aps.org/prd/abstract/10.1103/PhysRevD.103.L051901 LHeC IR layout’22 luminometer ➝ ⤳ 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1 y 0 0.05 0.1 0.15 0.2 0.25 0.3 0.35 0.4 0.45 /dy) BH s /dy) / (d corr s (d FCC-eh = 60 GeV e E = 50 TeV p E m µ = 2 x s m µ = 2 y s LHeC = 50 GeV e E = 7 TeV p E m µ = 5 x s m µ = 5 y s From paper in preparation y = Eg/Ee | poster |
Erik Crosman and John Horel Department of Atmospheric Sciences, University of Utah, Salt Lake City, UT; erik.crosman@utah.edu Lake SST Algorithms • Generally use a single satellite platform • Historically used split-window algorithms --Tuned to buoy if data available • Recent more sophisticated algorithms using radiative transfer models using ECMWF or NCEP reanalyses to estimate atmospheric profiles over various lakes to estimate the atmospheric variability observed in different lake locations (Hulley et al. 2011; McCallum and Merchant 2012) Motivation for Study •Lake surface temperature critical for ecology, climate change, and numerical weather prediction •The quality and availability of satellite- derived lake SST for cloudy seasons and smaller lakes in many regions is poor •No consensus on appropriate algorithms •Cloud contamination and sampling errors not well-documented •What is the path forward for obtaining improved lake SST? Satellite-derived Lake Surface Temperature: Review of Current State and Future Needs Key Sources of Error •Cloud contamination (insufficent cloud mask) •Sampling and representativeness, processing, limited QC flags •Geolocation and land contamination •Retrieval algorithm •Air-water interactions and diurnal effects . We gratefully acknowledge discussions with all members of the the GHRSST Near Shore Water Working Group (NSWWG), and helpful discussions with Jorge Vazquez, Ed Armstrong, Mike Chin, Simon Hook, Chris Merchant, Robert Grumbine and John D. Lenters and discussions with the Global Lake Temperature Collaboration (http://www.laketemperature.org/). Funding for this work is through NASA grant #NNH13CH09C entitled “Multi-sensor Improved Sea Surface Temperature (MISST) for IOOS.” We also are grateful to Chelle L. Gentemann and Remote Sensing Systems for the opportunity to collaborate with this work Chin, T.M., Milliff, R.F., and Large, W.G., (1998). Basin-scale, high- wavenumber sea surface wind fields from a multiresolution analysis of scatterometer data. Journal of Atmospheric and Oceanic Technology, 15: 741-763 Crosman, E., and J. Horel, 2009: MODIS-derived surface temperature of the Great Salt Lake, Remote Sensing of Environment., 113, 73-81 Fiedler, E., Martin, M. and Roberts-Jones, J. 2014. An operational analysis of lake surface water temperature. Tellus A. 66, 21247. DOI: 10.3402/tellusa.v66.21247 Grim, J.A., J.C. Knievel, and E. Crosman, 2013: Techniques for Using MODIS Data to Remotely Sense Lake Water Surface Temperatures. J. Atmos. Oceanic Technol., 30, 2434–2451 Hulley, G.C., S.J. Hook & P. Schneider, 2011, Optimized split-window coefficients for deriving surface temperatures from inland water bodies, Remote Sensing of Environment, 115, 3758-3769 Layden, A., Merchant, C., and MacCallum, S. 2015. Global climatology of surface water temperatures of large lakes by remote sensing. International Journal of Climatology, 35 (15). pp. 4464-4479. ISSN 0899-8418 MacCallum, S.N., and C.J. Merchant, 2012.:Surface Water Temperature Observations of Large Lakes by Optimal Estimation. MacCallum. Can J Remote Sensing, 38(1), 25 – 45 O’Reilly, C. M., et al. , 2015: Rapid and highly variable warming of lake surface waters around the globe, Geophys. Res. Lett., 42, 10,773– 10,781, doi:10.1002/ 2015GL066235 Riffler et al., 2015: Lake surface water temperatures of European alpine lakes (1989–2013) based on the advanced very high resolution radiometer (AVHRR) 1 km data set Earth System Science Datas, 7 (2015), pp. 1–17 Sharma, S., et al., 2015: A global database of lake surface temperatures collected by in situ and satellite methods from 1985–2009, Sci. Data, 2 Liu, G. et al. ,2015: Validating and Mapping Surface Water Temperatures in Lake Taihu: Results From MODIS Land Surface Temperature Products." Selected Topics in Applied Earth Observations and Remote Sensing, IEEE Journal of 8.3: 1230-1244 Cloud Contamination and Temporal Averaging Errors • Crosman and Horel (2009) required visual inspection of all | poster |
Towards prediction of low dimensional QoIs with data-driven LES closures in 2D turbulence Rik Hoekstra (rik@cwi.nl) , Wouter Edeling & Daan Crommelin Problem description Goal: ▶Predict low dimensional quantities of interest for a multiscale system. More specific: their statistical distribution. Learn a data-driven LES closure: 1 ”CNN” approach: ▶Unclosed component is a field, same size as solution. 2 ”Tau orthogonal” approach: ▶Unclosed components are time series. Why: ▶Learning time series is low dimensional and leads to explainable SGS terms. Large eddy simulation The coarse grained vorticity stream formulation of Navier-Stokes: ∂¯ω ∂t + ¯ J ( ¯ψ, ¯ω) = ν∇2¯ω + µ(¯F −¯ω) + r, (1) ∇2 ¯ψ = ¯ω, J (ψ, ω) := ∂ψ ∂x ∂ω ∂y −∂ψ ∂y ∂ω ∂x . (2) Subgrid scale (SGS) contributions are captured in: r = ¯ J ( ¯ψ, ¯ω) −J (ψ, ω). (3) For accurate LES we need a closure term: ˜r ¯ψ, ¯ω ≈r (ψ, ω). (4) ▶We apply: ▶a slow high fidelity solver, ▶a faster low fidelity solver which needs a closure term. ▶Parameter values for Earth sized aqua planet: ▶ν ≈4.4 · 10−6, µ ≈1.8 · 10−3. 1⃝Convolutional neural network as closure We use a CNN architecture inspired by Guan et al. [2]. The network consists of 11 2D-conv layers, with 5 × 5 kernels and periodic padding. The hidden layers have 64 channels. CNN ¯ω ¯ ψ ¯f ˜r ▶Trained on 1800 snapshots. ▶Correlation of 0.95 on test set. 2⃝Tau orthogonal method [1] Goal: track d low dimensional QoIs Qi(t) = ZZ qi(¯ω, ¯ψ)dxdy, i = 1, .., d. (5) Assume ˜r = d X i=1 τi(t)Pi(x, y, t), (6) and orthogonality ∂qi ∂¯ω, Pj = 0, if i ̸= j. (7) Now the i-th term of ˜r only influences Qi: dQi dt = resolved contributions + τi ∂qi ∂¯ω, Pi . (8) Track all Qi in the training domain using τi = dQi D ∂qi ∂¯ω, Pi E, dQi = Qref i −QLF i . (9) ▶It is possible to apply the Tau orthogonal method and the CNN simultaneously. [1] W. Edeling and D. Crommelin. Reducing data-driven dynamical subgrid scale models by physical constraints. Computers & Fluids, 201:104470, 2020. [2] Y. Guan, A. Subel, A. Chattopadhyay, and P. Hassanzadeh. Learning physics-constrained subgrid-scale closures in the small-data regime for stable and accurate LES. Physica D: Nonlinear Phenomena, 443:133568, 2023. Overview modeling approach ω(t = 0) HF ω(t) comp. expensive ¯ω(t = 0) LF ¯ω(t) r coarse graining eq. (1) + (2) integrate QoI: RR φ(¯ω, ¯ψ)dxdy 0 250 500 750 1000 days 3.6 3.8 4.0 4.2 4.4 Energy 1e 4 Results QoIs of the form Ei,j or Zi,j, which denote the energy/enstrophy in wave numbers i ≤∥k∥≤j. With 4 QoIs: E0,15, Z0,15, E16,21 and Z16,21. Training (500 days): 0 50 100 150 200 250 0 5 1e 8 dE0, 15 0 50 100 150 200 250 days 1 0 1e 8 dE16, 21 3.2 3.4 3.6 3.8 4.0 4.2 4.4 4.6 E0, 15 1e 4 0.0 0.5 1.0 1.5 2.0 Density 1e4 ref LF + TO CNN + TO LF Probability density functions ▶Adding the CNN centers the time series around zero. ▶Given the time series the tracking of the QoIs is exact. Extrapolation (5000 days): ▶Using mean of dQi series for TO method 3.25 3.50 3.75 4.00 4.25 4.50 4.75 5.00 E0, 15 1e 4 0 1 2 Density 1e4 ref LF LF + TO CNN CNN + TO 0.6 0.8 1.0 1.2 Z0, 15 1e 2 0 2 4 Density 1e2 ref LF LF + TO CNN CNN + TO 1 2 3 4 5 E16, 21 1e 6 0 1 Density 1e6 ref LF LF + TO CNN CNN + TO 0.2 0.4 0.6 0.8 1.0 1.2 1.4 1.6 Z16, 21 1e 3 0 2 4 Density 1e3 ref LF LF + TO CNN CNN + TO ▶The low fidelity simulation gives biased QoIs. Adding the TO method improves the distributions of E and Z in the higher wave numbers. ▶The CNN based closure works remarkably well. Adding the TO method with constant dQi does not improve it. Outlook Need better prediction for time series: ▶Fit a stochastic process to the time series. ▶Use (recurrent) neural network to predict the time series. ▶Use GAN to predict the time series. This research is funded by the Netherlands Organization for Scientific Research (NWO) through the ENW-M1 project ”Learning small closure models for large multiscale problems” CWI is the national research institute for mathematics and computer science in the Netherlands. ht | poster |
across subjects? Draw on knowledge from Will the session(s) be co-taught? Taught separately What methods would this discipline use to investigate the question? How does this discipline interpret the question? Is this building on existing knowledge? 1 Building on Current Practice 5 minute lesson plan – bridging subject boundaries Before they investigate, what Can Nuclear Power save the Planet? r Learning Objectives: 1. The generation of electricity using nuclear fission and fusion. 2. An appreciation of the environmental demands and challenges of doing so. Do they already need to know? A basic knowledge of the nuclear fission and fusion processes to investigate the technological requirements for the process. Challenging misperceptions? Acting as extension? areas of the school curriculum? In addition to science, students will explore draw on geography, religion, economics, history, mathematics and politics whilst investigating broader matters of things like global cultures and international relations.* 2 Developing Epistemic *Note from the Research team - this section can be used to link to specific Insight: How can the students be supported to answer these three questions? curriculum objectives especially if the big question goes beyond the requirements of the curriculum ? How would (someone in) this discipline know they had a good answer? Helping Hands… What expertise/ methods/norms of thought can you draw on from other disciplines to support or contrast? 3 Building Permeable Classroom Walls: Forming links across the curriculum other subjects Ideally, yes. Specialist knowledge needs to be gathered from different disciplines and brought together provide a complete picture. the need to draw on wider disciplines to answers these aspects of the question could be noted "within" the science lesson or could be embedded through coordinated delivery on related topics in Geography, politics, religious studies etc. What is the misperception/ boundary/ epistemology you are trying to address? Highlighting that science answers whether we can create nuclear power, but not if/how we should implement it. What it requires and what the consequences might be. What are the (global) risks and benefits? Can this be checked in another classroom? Evaluation and judging costs. Statistics on nuclear power contribution to carbon neutral targets (% of the overall energy portfolio?). Where the fuel comes from, the materials and resources needed to build stations. Where they need (or are likely) to be built, the geopolitical ramifications, infrastructure demands and costs. The influences of historical events (Chernobyl, Fukushima etc)**. **Note from the Research Team - students' understanding of How does this map on to other Science: How is nuclear power produced and how efficient it is, particularly the level of greenhouse emissions in relation to other sources of energy. Stewardship: Considers the ethical consequences, encouraging a global perspective – sharing responsibility. Science: Observation and experiment, repeat tests, analysing data about efficiencies. It is quantifiable. Stewardship: Considers the value/impact of nuclear power and its implications for our planet globally and for individual societies. More qualitative. Science: Objective and quantifiable data which can be repeated and tested by multiple sources. Stewardship: Draws on the ethical and values driven argument, referred to and justified by religious belief or worldviews. Mathematics: calculation of efficiencies Mathematics: analysis and calculation of data Mathematics: reliance on quantifiable data | poster |
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