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http://www.dialogycabddh.es/ © Dialogyca BDDH. ISBN 978-84-691-8286-4. Propiedad intelectual: M-000333/2010. Registro de marca: 2855599. Dialogyca BDDH es una base de datos y biblioteca digital que aporta los datos obtenidos del análisis literario y bibliográfico exhaustivo de obras escritas en diálogo. Esta información se distribuye en 6 áreas temáticas y 39 campos que facilitan su consulta. Mediante hiperlinks se contemplan sus variadas formas de difusión. Se parte del concepto de ‘obra’ para precisar a continuación diferentes aspectos útiles en su estudio. Además, se ofrece la digitalización de los testimonios -manuscritos o impresos- que se conocen, su descripción codicológica o tipobibliográfica y una bibliografía secundaria actualizada y descargable en PDF con indicación expresa del autor de cada documento. Dialogyca BDDH es el resultado de diez proyectos UCM/Santander-CAM (desde 2004) y seis proyectos de I+D financiados en convocatorias sucesivas desde 2007. En la actualidad, mantiene convenios o acuerdos con 48 bibliotecas en todo el mundo y sus registros analíticos se enlazan desde los OPAC de la Biblioteca Nacional de España, la Biblioteca Histórica Marqués de Valdecilla de la UCM, de la Biblioteca Menéndez Pelayo y de la Biblioteca de la Real Academia Española. Se integra, además, en ARACNE: Red de humanidades digitales y letras hispánicas (http://www.red-aracne.es/), que coordina los proyectos de once grupos de investigación y relaciona mediante un metabuscador común los resultados de 24 bases de datos o bibliotecas digitales especializadas. Su información se recupera desde Hispana y Europeana. I Workshop CLARIAH-CM: Humanidades Digitales y Tecnologías del Lenguaje, 30 y 31 de mayo de 2024 Dialogyca BDDH: Estructura, contenido y aplicaciones Biblioteca Digital de Diálogo Hispánico Equipo Directoras: Consolación Baranda Leturio y AnaVian Herrero. Comité de dirección y supervisión general: Consolación Baranda Leturio, María Casas del Álamo, Celia Faba Durán, Mercedes Fernández Valladares, Germán Redondo Pérez, AnaVian Herrero. Secretario: Germán Redondo Pérez. Gestores de la web: María Casas del Álamo, Germán Redondo Pérez. Conjunto de investigadores: Alejandro Alvarado Fernández, Consolación Baranda Leturio, Sara Bellido Sánchez, Emilio Blanco Gómez, Alejandro Cantarero de Salazar, María Casas del Álamo, Nicolas Correard, Paloma Cuenca Muñoz, Pierre Darnis, Celia Faba Durán, Carlos Fernández González, Mercedes Fernández Valladares, María Jesús Fraga Fernández Cuevas, Felice Gambin, Catalina García-Posada Rodríguez, Theodora Grigoriadou, Daniel Lozano Díez, Jerónimo Miguel, Sergio Montalvo Mareca, José Luis Ocasar Ariza, Fabrice Quero, Germán Redondo Pérez, Sergio Rodríguez Lorenzo, Julio Salvador Salvador, Lucía Sanz Gómez, AnaVian Herrero. Colaboradores: Amparo Alba Cecilia, Corinna Albert, Elvezio Canonica, Gabriel Andrés Renales, María Soledad Arredondo Sirodey, Eleonora Arrigoni, Sònia Boadas, Gonzalo Cantarero de Salazar, Roberto Carmo Antunes, Ernesto Javier Carrillo Barroso, Antonio Castro Díaz, Rosa Chenlo, Pedro Conde Parrado, Pedro Luis Críez Garcés, Roger Friedlein, Donatella Gagliardi, Javier Espejo Surós, Jesús Gallego Montero, Marcos García Pérez, Jesús Gómez, Luis Gómez Canseco, Guillermo Gómez Sánchez-Ferrer, Esther Gómez Sierra, María Cristina González Hernández, José Miguel González Soriano, Milagro Laín Martínez, Óscar Lilao Franca, Santiago López-Ríos Moreno, Amaruc Lucas Hernández, María Luisa Martín Murillo, Alejandro Martínez Berriochoa, Ángel Montero Herrero (en 2007-2008), Ana Moure Casas, Eva Nieto McAvoy, Virginia Oprisa, Erika Petersen O’Farrill, Rafael M. Pérez García, Laura Puerto Moro, Alberto del Río Nogueras, Guadalupe Rodríguez Domínguez, Doris Ruiz Otín, Carlos Sainz de la Maza Vicioso, Javier San José Lera, Raquel Suárez García, Esmeralda Sánchez Palacios, José Miguel Sardiñas Fernández, Selena Simonatti, Pilar Torres Vicente, Juan Miguel Valero Moreno, AurelioVargas Díaz-Toledo. | poster |
Anaplastic astrocytoma (AA) is a rare, malignant brain tumor that arises from astrocytes, the supportive cells in the nervous system. Anaplastic astrocytomas (grade III) may also be called a “grade III glioma” or “high-grade glioma.” Symptoms of anaplastic astrocytoma can result from an increase of pressure in the brain. This occurs as the tumor grows larger and takes up space, compressing healthy brain tissue within the fixed volume of the skull. If not diagnosed early, tumors can grow large enough to block the normal flow of cerebrospinal fluid in the brain [1]. In this study, the regulation of GPR45 gene and the effect of lncRNA-CYTOR on it in anaplastic astrocytoma were examined using bioinformatics databases. Methods Conclusions The 2nd International Conference on Biotechnology and Global Development Investigate the relation between GPR45 gene and lncRNA-CYTOR in anaplastic astrocytoma Elnaz Nasiriyan1, Negar Amidi, Ali Attaripour Isfahani1, Tahereh Sadeghian-Rizi2,* 1 Department of Biological Science and Technology, Najafabad Branch, Islamic Azad University, Najafabad, Iran 2,* Department of Biotechnology, Faculty of Biological Sciences and Technology, Shahid Ashrafi Esfahani University, Isfahan, Iran Bibliography First, this gene was structurally analyzed in GeneCards then GPR45-related single nucleotide polymorphisms (SNPs) and microRNAs were found in GWAS Catalog and NCBI databases. Ultimately, the LncRNADisease database (version 2.0) helped to find a long non-coding RNA (lncRNA) connected with the GPR45 gene signaling pathways. [1] M. Caccese, M. Padovan, D. D'Avella, F. Chioffi, M.P. Gardiman, F. Berti, F. Busato, L. Bellu, E. Bergo, M. Zoccarato, M. Fassan, V. Zagonel, G. Lombardi, Anaplastic Astrocytoma: State of the art and future directions, Crit. Rev. Oncol. Hematol, 153(2020), 103062. The GPR45 gene, which encodes a member of the G protein-coupled receptor (GPCR) family and is located on chromosomal position 2q12.1, mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. According to findings from the GEPIA2 database, the GPR45 gene is highly expressed in astrocytoma. The analysis Indicated that the incidence of the SNP:rs2576789 can lead the cells to Anaplastic astrocytoma and outcome the involved miRNA- 4435-1 and lncRNA-CYTOR in this process. Through the process of this disease, the disease- associated SNP is located on the mRNA and the miRNA-4435-1 binds to 3’UTR of GPR45 mRNA as an activator. When lncRNA-CYTOR, binds to miRNA-4435-1, turns on miRNA- 4435-1 and the GPR45 gene is activated, finally intensifies the tumorigenesis of anaplastic astrocytoma. The present study inferred that, the interaction of lnc-CYTOR with rs2576789 could be useful biomarkers for the diagnosis of anaplastic astrocytoma. The miRNA-4435-1 proves also that GPR45 is an effective gene in anaplastic astrocytoma outbreak and its tumorigenesis, so there is hope for early diagnosis this malignant brain tumor. Introduction Results Anaplastic Astrocytoma Normal astrocytes Different parts of the brain tissue 0 1 2 3 4 5 6 Other brain diseases Anaplastic astrocytoma miR-4435-1 Up Regulated Down Regulated Figure1: Anaplastic Astrocytoma Diagram1: GPR45 gene expression level in different tissues of the human body. Diagram2: GPR45 gene expression level in anaplastic astrocytoma and other brain diseases. Figure2: The volcanic map of identification of significantly expressed miRNA in Anaplastic Atrocytoma. The red dots represent significantly up-regulated miRNAs and the green dots represent significantly down- regulated miRNAs. miRNA volcano | poster |
Distributed Text Services (DTS) A Community-driven Text Interoperability API Linked Pasts 6, University of London and British Library, December 2-16, 2020 DTS Community 46 Members Communication via Google Group list Technical exchanges: GH issues Minutes: meeting notes GH repo Want to join? Subscribe to the Google Group Why DTS? DTS provides a standard way for clients to interact with collections of TEI documents. A standard API allows users to access many text collections using the same client software. It also allows editors to publish text collections in a usable way that existing clients can use. What is DTS? Goal: enable machine-actionable operations across a wide variety of TEI texts. As DTS strives for genericity, it does not dictate: - how collections should be organized - type of persistent identifiers to use - what ontologies to use for metadata - how the texts are structured. Classes of objects in DTS Collections: - Hold metadata - Serve as a catalog - May be: - nested - readable - chunked into citable textual elements References: hold identifiers & metadata for subsections of documents Passages: hold textual content Endpoints & Operations Collections endpoint: - List available collections - Support for pagination & virtual collections - Navigate between nested collections Navigation endpoint: - List available text passages Documents endpoint: - Retrieve the text of a document Specs: w3id.org/dts Demo: web + notebooks FAQ page DTS-compliant resources APIs ENC Alpheios Perseids EDH Beta maṣāḥǝft A Generic Text API DTS supports: - Multi-level/competing text hierarchies - Any identifier scheme (*) - Non-homogeneous text hierarchies Implementations TEI publisher client/server Perseids DTS API Nautilus + MyCapytain | poster |
Background Stereotyping among Football Fans: Terror Management Perspective Abdulkadir Kuzlak, MS & Nuray Sakallı-Uğurlu, PhD Middle East Technical University, Department of Psychology, Ankara, Turkey Method Results & Discussion Violence and stereotyping are common among Turkish football fans and these turn into harmful acts against property and most importantly human life. Terror Management Theory (TMT) states that the unique human awareness that each human will die one day not only make us plan ahead but also behave differently, mostly negatively, when reminded with our own death. When participants are primed with Mortality Salience (MS) they evaluate other group members more negatively (Greenberg et al., 1990) The main purpose of this study was to understand whether stereotyping among football fans is rooted on existential concerns. Presented stereotyping difference between MS and dental pain (DP) conditions partially explain stereotyping among football fans. Subjects. 186 students from Middle East technical University 122 females whereas 64 males with a mean age of 21.47 (SD = 2.3) from various departments. Materials. Self-Esteem Scale (Rosenberg, 1965) – Mortality Salience Manipulation – Positive and Negative Affect Schedule (Watson, Clark, & Tellegen, 1988) – Word Search Puzzle – Stereotypical Thinking about Football Fans Scale (Developed within this study) – Sport Spectator Identification Scale (Wann, & Branscombe, 1993) Design and Procedure. Between subjects experimental design with 6 conditions (3x2, affiliated teams x experimental conditions) Self-esteem measured – Primed with MS or DP – Stereotyping toward supported or opponent team fans are evaluated – Identification with supported team measured FB fans reported significantly more interpersonal relations stereotyping towards FB fans in MS than in DP condition, F(1, 38) = 4.79, p = .035. Although it was expected that negative stereotyping would be higher in MS than in DP conditions, a positive out-group stereotyping was found. GS fans reported more competence stereotyping toward FB fans in MS than in DP condition, F(1, 81) = 3.14, p = .080. Findings seemingly contradict the previous results of TMT studies which were negative evaluation toward out-group members. But TMT literature shows that participants try to justify their worldview, in this sense GS fans justify that they perceive FB fans as competent in MS condition and FB fans justify GS fans are less competent in MS condition. Positive in-group stereotyping also corresponds with TMT findings. Beside, for DV, a scale without pessage was used which is different from most of the TMT studies. A study using pessage-like-DV and using highly identified football fans would be better for future research. References Rosenberg, M. (1965). Society and the adolescent self-image. Princeton, NJ: Princeton University Press Wann, D. L., & Branscombe, N. R. (1993). Sport fans: Measuring degree of identification with their team. International Journal of Sport Psychology, 24 (1), 1 - 17 Watson, D., Clark, L. A. & Tellegen, A. (1988). Development and validation of a brief measure of positive and negative affect: The PANAS Scales. Journal of Personality and Social Psychology, 54 (6), 1063 - 1070. Doi: 10.1037/0022-3514.54.6.1063. Greenberg, J., Pyszczynski, T., Solomon, S., Rosenblatt, A., Veeder, M., Kirkland, S., & Lyon, D. (1990). Evidence for terror management theory II: The effects of mortality salience on reactions to those who threaten or bolster the cultural worldview. Journal of Personality and Social Psychology, 58 (2), 308 - 318. Doi: 10.1037/0022-3514.58.2.308. Insult Items: Contemptible – Loser – Turncoat – Liar – Worthless – Prick – Studpid – Coward – Feminine Competence Items: Successful – Strong – Talented – Skillful – Self- confident - Fast Interpersonal Relations Items: Familiarity – Pure-minded – Calm – Adaptive - Positive Higher interpersonal relations stereotyping was made toward supported team fans Higher compet | poster |
FUDGE-5G: Fully Disintegrated Private Networks for 5G Verticals David Gomez-Barquero*, Antonio Borges†, Andre S. Gomes†, Luis Cordeiro†, † Joao Hen- riques†, Kashif Mahmood‡, and Sebastian Robitzsch§ *Universitat Politécnica de Valencia, Valencia, Spain †OneSource, Coimbra, Portugal ‡Telenor Research, Fornebu, Norway §InterDigital Europe, Ltd., London, United Kingdom The NPN concept allows for designing, deploying, and interconnecting capabilities for the specific needs of the use cases, motivating the NPN deployment in the first place. 3GPP studies two types of NPNs, falling under the categories of Standalone Non-Public Networks (S-NPNs) and Public Network Integrated NPNs (PNI-NPNs) PLATFORM ARCHITECTURE USE CASES NPN BENEFITS PROJECT COORDINATOR FUDGE-5G assumes: a unified access domain across all Access Networks as the shared communi- cation denominator; 1. utilising Software-defined Networking (SDN) on both control and user planes is fully supported by the platform; 2. Network Function Virtualisation (NFV)-enabled infrastructure. 3. Both for control and user plane 5G services, FUDGE-5G offers a Service-based Architecture platform realization covering: • unified service routing; • orchestration; • monitoring capabilities. 5GC lists innovations around: • 5G IP and Opportunistic Multicast (OMC); • 5G Time Sensitive Networking (TSN); • 5G Local Area Network (5GLAN); and interconnected S-NPNs. Service routing at the control plane is based on Name-based Routing (NbR), one of the three official deployment options of a Service Communication Proxy (SCP). User plane service routing offers the integration of NbR, which is complemented by a novel resource scheduling. With NPNs, the network can be designed, optimised, dimensioned and customized to serve different needs of enterprise and industrial verticals. It allows for: • tight integration of UEs with the RAN and 5GC; • customised QoS traffic flow support; • better coverage (optimized cell location); • high security (isolation); • adaptability and scalability; • greater flexibility; • high efficiency; • lower latency overall. Cloud Solution providers from Advisory board Industry 4.0 Stakeholder 5G Virtual Office Stakeholder PPDR Stakeholder Concurrent Media Delivery Stakeholder Interconnected NPNs Stakeholder The use case aims to illustrate a typical remote production and media delivery scenario at the same time, but in this case using 5G technology. The main objective in this UC is to provision transparent mis- sion-critical services to the end-user independently of the under- lying telecommunication infrastructure. In this UC, innovations will allow hospital staff to be able to work more effectively and for medical knowledge and expertise to be distributed over a much wider area. This UC aims at demonstrating the applicability of S-NPNs and their integration with 5GLAN and TSN, replacing fixed and wired alternatives for industrial communications with 5G. The main motivation of this UC is deployment of 5GLAN in case of federated 5G S-NPN and authentication and authorization of sub- scribers across multiple domains. Prof. David Gomez-Barquero Universitat Politecnica de Valencia iTEAM Research Institute Camino de Vera info@fudge-5g.eu /company/fudge-5g/ /fudge5geu This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 957242 C M Y CM MY CY CMY K fudge-publication-poster_v2-1.pdf 2 18/05/2021 15:13:17 | poster |
Very high broadsense heritability for the root angle in both species = 0,82. WEB LINK : HTTPS://WWW.SOLACE-EU.NET GENETIC VARIATION OF WHEAT SEEDLING ROOT ANGLE C. COLLET, B. MOTTOULLE, T. DAGBERT, G. LOBET AND X. DRAYE EARTH AND LIFE INSTITUTE, UNIVERSITÉ CATHOLIQUE DE LOUVAIN, BELGIUM. CONTACT: clothilde.collet@uclouvain.be Below-ground parts of plants play a significant role in water and nitrogen extraction, and adaptation to changing environments. BELOW-GROUND PARTS OF PLANTS, OUR KEY PLAYERS ! Seminal root angles of cereal seedlings are good predictors of top soil exploration during crop establishment. PHENOTYPING ROOT GROWTH DYNAMICS Seedlings growing at different matric potentials (height above the water level) displayed a significant root angle plasticity in the two panels, despite the very small amplitude of potential (25 cm). This plasticity is genetically variable only in bread wheat. à The mean seminal root angle is 96° à The mean seminal root angle is 125° ^^^^ Water ^^^^ Illustration of extreme bread wheat varieties SEMINAL ROOT ANGLE EXPERIMENT This research is part of the European project SolACE : • Two diversity panels (bread wheat panel and durum wheat panel) for association genetics. • Advanced phenotyping experiments in equipped fields and controlled conditions platforms. • Emphasis on a combined deficit of water and nitrogen. Knowing the variability and heritability of root angle is a preliminary step towards improvement of seedling root architecture. à 2 experiments presented here as part of SolACE project. Identification and tracking of root tips in image sequences : • Root growth rate. • Emergence. • Maximum length. • Apical diameter. RootPhAir : • Aeroponics. • High throughput phenotyping. • Time-lapse image sequences with 2h resolution. • Affordable and non- invasive technique. CONCLUSIONS & PERSPECTIVES Seminal root angle experiment : • The large heritability of root angle suggests QTLs will be detected. • Wheat seminal root angle responds to small differences of water deficit. • In bread wheat, this response is genotype-dependent and may lead to unexplored adaptation possibilities. Further analyses : • Characterisation of genetic determinism for the root traits. © Laure Beff Other data sources will be mobilised : • Aeroponics (RootPhAir) : dynamic root traits. • 4PMI platform (INRA Dijon). • Field data (Syngenta, Arvalis, INRA). Albidum Zitnica | poster |
Gaia DR3 determination of the Galactic bar pattern speed Romero-Gomez M1, Jiménez-Arranz, Ó4, Chemin L3, Hunt J5, Khanna S2, Drimmel R2, Poggio E2, Ramos P6, Andrae, R7 1 Institut de Ciències del Cosmos (ICCUB), Universitat de Barcelona (IEEC-UB), Barcelona, Spain 2 INAF - Osservatorio Astrofisico di Torino, Torino, Italy 3 Instituto de Astrofisica, Universidad Andres Bello, Santiago RM, Chile 4 Division of Astrophysics, Lund Observatory, Sweden 5 University of Surrey, United Kingdom 6 National Astronomical Observatory of Japan, Tokyo, Japan 7 Max-Planck-Institut fur Astronomie, Konigstuhl 17, D-69117 Heidelberg, Germany Previously, in Gaia Collaboration, Drimmel+2023... ●We selected RGB stars in the Galactic plane using Gaia gspphot astrophysical parameters. We used the 6D (positions and velocities) sample, including about 5.7M RGB stars towards the inner disc. ●3D velocity maps in cylindrical coordinates show the outstanding signature of the Galactic bar. ●Using a bisymmetric model of the tangential velocity component, we derive the position of the corotation radius of the bar, and from the tangential velocity curve, an estimate of the bar pattern speed. In the present study… ●We select RGB stars from Andrae, Rix & Chandra (2023) using XGBoost algorithm, which derives metallicities, effective temperatures and gravities trained using APOGEE stellar parameters and including CatWISE magnitudes. ●The catalogue now contains about 12M RGB stars in the Galactic plane. ●We make NEW 3D velocity maps in cylindrical coordinates, now taking into consideration the correlations between the astrometric variables and propagated to the galactocentric coordinates. ●New velocity correlation maps show vertex deviation of the local velocity elipsoid. In the present study… ●Alternatively to the experimental method used in the Gaia Collaboration, Drimmel+2023 paper, we use the Tremaine-Weinberg version of the code in Bovy+2019 to estimate the pattern speed of the Galactic bar from this new dataset. Results of the corotation radius and bar pattern speed are consistent with the ones found in the Gaia Collaboration paper. Note that… The estimated values of the pattern speed using the TW method show a strong dependence on the assumed angular orientation of the Galactic bar, and the maximum galactocentric radius defining the bar region. Some inherent to the method might not apply. Preliminary results ●A thorough analysis of the method when applied to simulated data shows a high sensitivity of the pattern speed with the estimation of the bar region or orientation angle. The hypothesis of a density gradient following an exponentially decreasing elliptical pattern might not be realistic. | poster |
24th International Conference on Evaluation and Assessment in Software Engineering 14-16 June, Oulu, Finland EASE welcomes papers addressing topics related to evaluating and assessing software products, processes, practices, tools & techniques including: • Defect and quality prediction • Estimation, decision-making, heuristics & biases in SE • Evaluation and comparison of software technologies (e.g. IoT, Context–Awareness, Cyber-physical) • Human factors and behavioral aspects of SE • Infrastructure and teachniques for conducting empirical studies • Inter- or multi-disciplinary studies intersecting SE • Modeling, measuring, and assessing product/ process quality, or SE success • Modeling, measuring, and assessing SE productivity and job performance • Software analysis, testing, verification, validation • SE analytics and metrics • Software project and knowledge management • Software technology transfer to the industry • Theory development and evaluation EASE also welcomes studies with negative findings or non-significant results. Similarly, EASE welcomes papers employing any of the following empirical methods: • Qualitative research including action research, case study, ethnomethodology, grounded theory, qualitative surveys (interviews) & qualitative simulation (e.g. protocol analysis) • Quantitative approaches including benchmarking, experiment, data science (i.e. AI or ML-based approaches), longitudinal studies (e.g. cohort studies), optimization studies, quantitative simulation, quasi-experiment, questionnaire surveys & repository mining. • Systematic literature review including case survey, critical review, meta-analysis, qualitative synthesis, & scoping review (systematic mapping) • Engineering research (also called “design as research” & “design science research”) • Mixed methods and multi-methodology • Replication studies • Meta-science (e.g. papers about research methods and methodological issues, whether empirical or conceptual). General Chairs Burak Turhan University of Oulu Sira Vegas Universidad Politécnica de Madrid Organization Chair Kari Liukkunen University of Oulu Program Chairs Maria Teresa Baldasarre University of Bari Paul Ralph Dalhousie University Vision and Emerging Results Chairs Aldeida Aleti Monash University Valentina Lenarduzzi University of Oulu Tentative dates Workshops proposals deadline December 2, 2022 Workshops proposals notifications December 19,2022 Full papers abstracts deadline January 13, 2023 Full papers deadline January 20, 2023 Full papers notifications March 6, 2023 Rest of tracks deadline March 10, 2023 Rest of tracks notifications April 16, 2023 Camera ready deadline April 28, 2023 The International Conference on Evaluation and Assessment in Software Engineering (EASE) is one of the premier conferences for research related to empirical software engineering. The EASE full research papers track seeks high quality submissions of technical research papers describing original and unpublished results. EASE 2023 Preliminary Call For Papers Image by David Mark from Pixabay REVIEW PROCESS Authors are encouraged to consult the ACM SIGSOFT Empirical Standards for Software Engineering Research at https://acmsigsoft.github.io/EmpiricalStandards/ when designing their studies and writing their manuscripts. EASE 2023 will employ a double-anonymous review process. Authors are also expected to comply with the SIGSOFT Open Science Policy (i.e., to properly archive data and artifacts to the extent ethically and practically possible, and include a links in a Data Availability section in their manuscripts). More details regarding the review process will be released closer to the submission deadline. CONFERENCE TRACKS AND SUBMISSIONS EASE 2023 features the following tracks: full papers, vision & emerging results, short papers & posters, industry and doctoral symposium. There will also be co-located events, including workshops and tutorials, and a track planned for journal-first presentations. All papers | poster |
POSTER SESSION THE PAPER IN BRIEF The paper aims to gain an understanding of the characteristics and requirements of the logistics pertaining to the reverse supply chain of circular sustainable floor coverings, as a crucial part of enabling circulation of the material, and to identify the regulations that affect the reverse logistics. The methodology includes a literature search and discussions with floor coverings sector stakeholders. The results show that there are special characteristics to consider pertaining to the logistics of the floor-coverings reverse supply chain, when increased circularity is aimed at, such as unpredictable supply, and several regulations affect logistics activities. The paper contributes to a better understanding of the logistics of reverse supply chains in the floor coverings sector. RESULTS • Major changes are needed to the current reverse supply chain if it is to become circular • Regulations affect circular floor coverings’ logistics. • The unpredictable supply of construction and demolition waste from various sources, posing challenges to e.g. to the collection and pretreatment. • In collection, contamination should be minimized for high quality of the collected material. Separate collection is the most efficient way to ensure the quality. • Streams from consumer sources are more scattered than those from commercial buildings. • Separate collection of all floor coverings together would require major material sorting before treatment. • Building centralized recycling facility to perform local pretreatment like separation and shredding would reduce the need for transportation capacity, carrying only material that will actually be recycled. • Planning of the material and installation of the floor coverings will set the direction of reverse supply chain activities and usability of the material after its initial use. • A need for new actors or role changes of current actors in the reverse supply chain to allow circulation of the materials. CHALLENGE The construction and demolition industry has significant potential for recycling and reuse due to its high volume of waste streams. One challenge, besides collecting the materials, is the location of related activities like sorting and pretreatment to avoid unnecessary transportation of not recyclable materials. Today, no widespread systems for collecting floor covering waste generated from e.g., demolished buildings or transport vehicles, or renewal activities. Some companies have developed their own systems, but a lack of logistics systems for collecting floor coverings and pretreating them locally has been identified as a major barrier to achieving circularity. CIRCULAR SUPPLY CHAIN MODEL The waste generation and collection phase of the value chain determines the fate of the waste and the recyclability of the waste and further the quality of the waste as a secondary raw material (SRM) and the continuity of supply ACKNOWLEDGEMENTS The authors wish to acknowledge the ‘CISUFLO’ (CIrcular SUstainable FLOor coverings) project, which has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement ID 101003893. The content reflects solely the authors’ views, and the EU is not responsible for any use of the information it contains. Identifying reverse logistics and related regulations in the circular supply chain of sustainable floor coverings Rosa Palmgren, Elina Pohjalainen, Margareta Wahlström, Ville Hinkka, Ismo Ruohomäki Design & products •Material choices and recyclability Waste generation •On-site sorting, dismantling Waste collection •Collection systems Sorting & separation •Feedstock quality Recycling/processing •Production of SRMs SRM markets •Use in manufacturing, market demand FLOOR COVERINGS REVERSE SUPPLY CHAIN Currently, floor coverings are collected mainly as mixed waste from construction and demolition sites and incinerated or landfilled. Ideally, the circularity of floor coverings would star | poster |
Measuring Stellar Long Surface Rotation Periods by Combining Multi-Sector/Cycles Long Cadence Data from TESS D.B. PALAKKATHARAPPIL¹, M. GILLES¹ ², R.A. GARCÍA¹, A. HAMY³, A. PRIN³, S.N. BRETON⁴, S. MATHUR⁵ & A.R.G. SANTOS⁶ 1. Université Paris-Saclay, Université Paris Cité, CEA, CNRS, AIM, F-91191, Gif-sur-Yvette, France, 2. ESTACA Paris-Saclay, Montigny-le-Bretonneux 3. École Centrale-Supélec, Univesité Paris-Saclay 4. INAF - Osservatorio Astrofisico di Catania 5. IAC - Instituto de Astrofisica de Canarias and ULL 6. Instituto de Astrofísica e Ciências do Espaço, Universidade do Porto, CAUP Introduction The evolution of surface magnetic features on stars, such as spots and faculae, produce modulations in light curves. These modulations allow us to measure the surface rotation period, Prot, of stars from Main Sequence (e.g. McQuillan et al. 2014, Santos et al. 2019, 2021) to Red Giant stars (Ceillier et al. 2017). Nevertheless, the effectiveness of determining Prot heavily depends on the length of the observation period. Previously, apart from the long observation campaigns of TESS (Ricker et al. 2015), it was not possible to measure Prot longer than about 13 days, half of TESS's 27-day sector observation period. TESS has completed two all-sky observations; combining this multi-sector data allows us to probe rotation periods beyond the typical limit of around 13 days. Measuring the rotation period from combined multi-sector data is challenging due to inter-sector gaps (~13 days), sector gaps (over years), and phase shifts in the light curve while combining long-gapped data. In this work, we evaluate the limits of going up to ~20 days from at least two continuous sectors in multiple campaigns, minimum possible multi-sector/cycle configuration. We assess the best strategies to extract Prot and provide yields based on Kepler (Borucki et al. 2010) data observed as TESS cycles. Identification of bad Sectors & Background correction PYTADACS Calibration TESS QLP Light Curves The MIT Quick Look Pipeline (QLP, Huang et al., 2020) generates light curves for approximately 19 million stars from FFIs. The 'SAP_FLUX' data product from QLP provides normalized best aperture photometric flux that is corrected for background without detrending the signal, ensuring that periodic features are preserved for accurate rotational period analysis. Additionally, the availability of pre-processed light curves eliminates the need to download Full Frame Images (FFIs) and compute light curves from scratch. However, several calibration strategies should be done to obtain precise rotation periods, as explained below. In a single sector, significant flux fluctuations can occur (Fig. 1, Sector 26), likely resulting from background calibration issues within the QLP. Such variations significantly compromise the accuracy of the Prot calculations, whether using the Autocorrelation Function (ACF) or the Global Wavelet Power Spectrum. It is crucial to identify these affected sectors and either remove or correct them for more reliable Prot estimation. The Fig. 2 on the right illustrates the estimation of an accurate period post- correction. Proper stitching of Light curves TESS data include inter-sector gaps of approximately 6 hours to 1 day around every ~13 days and sector gaps of 1-2 days. QLP flux is normalized by sector, which limits analysis to shorter rotation periods. To derive longer rotation periods, it is essential to properly stitch light curves across these gaps. As depicted in Fig. 3, without adequate stitching, the estimated rotation period will be biased. A stitching routine utilizing Bayesian inference, adapted from the TASOC pipeline (Handberg & Lund 2016, Handberg et al., 2021), has been implemented in PYTADACS (soon available through git, García et al. in prep.). This approach allows for the detection of longer periods, as illustrated in Fig. 4. Rotation Period Estimation After the correction of sectors and stitching of the light curve, a filter is appli | poster |
Hanle rotation signatures in Sr I 4607 Å Franziska Zeuner 1, Luca Belluzzi 1,2,3, Nuno Guerreiro1, Renzo Ramelli 1 and Michele Bianda1,3 1 IRSOL Istituto Ricerche Solari “Aldo e Cele Daccò”, Università della Svizzera Italiana (USI), CH-6605 Locarno-Monti, Switzerland 2 Leibniz-Institut für Sonnenphysik (KIS), D-79104 Freiburg i.Br., Germany 3 Euler Institute, Università della Svizzera Italiana (USI), CH-6900 Lugano, Switzerland Scattering polarization and Hanle rotation ●The limb of the Sun is linearly polarized due to scattering. ●Magnetic fields modify scattering polarization via the Hanle effect. ●One signature of the Hanle effect is a rotation of the polarization plane (e.g., observe Stokes U). ●One of the strongest linear polarization signals in the photosphere are found in the Sr I 4607 Å line. ●Hanle rotation signatures have been observed in many other lines, but they have not been detected yet in Sr I. ● observe the linear polarization in the Sr I 4607 Å line close to the limb, where zero Stokes U is expected ● We demonstrated the existence of Hanle rotation signatures in Sr I from weak longitudinal magnetic fields clearly for the first time. ●We used a new measurement technique for achieving high absolute accuracy. ● These signatures have an invaluable diagnostic potential. Contact: franziska.zeuner@irsol.usi.ch Link to Zeuner+ 2022, A&A 662, A46 Method U Q maximum zero Observation High-precision spectropolarimetry at the IRSOL observatory, Locarno: ● using a high-resolution spectrograph, slit perpendicular to the limb, +Q parallel to limb ● and ZIMPOL (fast modulating to suppress seeing- induced cross-talk) ● in combination with a new slow modulation technique (to achieve high zero level accuracy, see Zeuner et al. 2022 (SPIE Proc.)) Academic example of the linear polarization (Stokes Q and U) of the Sun’s limb from pure scattering. Polarization profiles at the limb (Stokes I and Q), and at one position with some magnetic activity (indicated by orange arrows in the previous figure showing the observed Stokes images). Profiles with suff- icient signal-to-noise are fitted with a Gaussian or the first derivative of a Gaussian (St- okes Q and V, respectively.) Low signal-to-noise profiles are spectrally averaged over a few pixel (orange shaded ar- eas). Sr I Stokes U profiles are clearly single lobed. Data reduction ● Applying ZIMPOL standard data reduction (dark frame and polarimetric calibration). ● Demodulating the slow modulation states to correct Stokes Q and U from systematic errors. ● Removing the mean of the Stokes V image (not corrected by slow modulation). ● Fitting the Stokes Q profiles in Sr I, Stokes V in Sr I and Fe I, and averaging Stokes U in a small spectral region within the core of both lines to asign each limb distance a polarization amplitude. Positive and negative Stokes U signals are visible in Sr I. Analysis limb Observed full St- okes images for 70 min integr- ation time at the limb, scattering polarization (St- okes Q) most prominently visi- ble in the Sr I line, not in the neighbouring Fe I line. Longitdinal Zeeman induced Stokes V is stro- nger in Fe I be- cause of its high- er Landé factor. The Stokes U amplitude is correlated with the Stokes V amplitude in Sr I. Therefore, cross-talk from Stokes Q to U can be ruled out as a source for Stokes U in Sr I. Such a correlation is not demonstrated in Fe I, therefore any cross- talk from Stokes V can be excluded as a source for Stokes U in Sr I. The transversal Zeeman effect can be excluded due to the single lobed shape of the Stokes U profiles. However, the correlation shows that longitudinal magnetic fields are a possible source for Stokes U and Stokes V. Correlation of the linear polarization amplitde in U (normalized to the maximum) with the cir- cular polarization ampli- tude V (normalized to the maximum), and fit- ted linear regressions. Conclusions | poster |
Three-dimensional mapping of organ geometry Laura Blackiea*, Pedro Gaspara, Lisa Gartnera, Hannah Beckwithb, Salem Moslehc, Lingjin Kongb, Yuhong Jina, Agata P. Zielinskaa, Todd Schoborgd, L. Mahadevane, John Thomasb, Ben Stattonb, Uday Patelf, Philip Lungf, Bernhard Kainzg, Irene Miguel-Aliagaa a Francis Crick Institute, London, UK; b Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK; c Department of Natural Sciences, University of Maryland Eastern Shore, MD, USA; d Department of Molecular Biology, University of Wyoming, WY, USA; e School of Engineering and Applied Sciences, Harvard University, MA, USA; f London North West University Health Care NHS Trust; g Department of Computing, Imperial College London, London, UK *laura.blackie@crick.ac.uk References (1) Blackie, Gaspar et al (2024) The sex of organ genometry. Nature. (2) Masselink et al (2019) Broad applicability of a streamlined ethyl cinnamate-based clearing procedure. Development. (3) Schoborg et al (2019) Micro-computed tomography as a platform for exploring Drosophila development. Development. (4) Arshadi et al (2021) SNT: a unifying toolbox for quantification of neuronal anatomy. Nature Methods (5) Yushkevich et al (2006) User-guided 3D active contour segmentation of anatomical structures: Significantly improved efficiency and reliability. Neuroimage. Loss of 3D information Opaque cuticle and toxic, long protocols Hard to label multiple organs at once Low throughput Loss of organ relationships Aim: map 3D organ shape and relationships Imaging method Confocal Light sheet Requires dissection Dissected Drosophila gut stained with DAPI imaged by confocal microscopy MicroCT Analysis methods Proximity to organ (μm) 590 295 442.5 147.5 0 767 0.00 0.25 0.50 0.75 1.00 75 25 50 100 0 Position along whole gut length (%) Distance to ovaries (mm) Left ovary n=44 Right ovary n=44 Extending to the human gut Segmentations - organ proximity analysis The gut tube of flies and humans is longer than the body so must fold and coil in order to fit into the abdomen. Does the gut fold into a stereotypical defined shape or is it random? Gut length differs between male and female flies - does gut shape also differ? Is gut shape important for gut function? To answer these questions we developed 3D imaging methods and 3D image analysis techniques(1). We scaled up micro-Computed Tomography (microCT) scanning(3), an x-ray based technique, by improving mounting methods. We mount 10 flies in a p10 pipette tip and stack four tips to scan ~40 flies in one run. Coupled with an automated sample changer, this allows us to scan 100s of flies automatically. Fly with GFP labelled gut cleared by 2Eci(2) and scanned by lightsheet microscopy. (Left) autofluorescence gives overview of fly body, (right) coiled gut can be seen in situ. 3D info remains intact - no dissection Most variable Least variable Overall mean Female mean Male mean 0.00 0.05 0.10 0.15 0.20 0.25 R L Ovary volume (mm3) *** n=60 90O 81.8% 6.8% 11.4% n=44 We used the ITKsnap software(5) to segment visible organs including the gut, ovaries and central nervous system. We then developed a method to measure the proximity between these organs and along the length of the gut. We identified several interesting asymmetries in organ arrangement for example the stomach more often contacts the fly’s right ovary. The fly’s left ovary is on average bigger than the right (left). Secondly we noted the fly’s stomach most often joins the gut from the left-hand side but a minority of individuals demonstrated an inverted arrangement (right). Left, example heatmap displayed on segmentation of gut showing gut proximity to ovaries (red = near, blue = far). Right, graph showing distance between gut and ovaries plotted along the length of the gut. We extracted parameters from the centreline including curvature, torsion and radius and found that females have higher curvature of their central midgut loops than males. Centrelines | poster |
Jonathan D. Geiger Lisa Kolodzie Jascha Schmitz Mareike Schumacher RaDiHum20-Webseite Webseite der DHd2024 RaDiHum20 auf Spotify Wissenschaftskommunikation (WissKomm) ist ein breites Feld des Managements wissenschaftlicher Kommunikate. Es kann zwischen einer internen WissKomm und einer externen unterschieden werden. Die interne Spielart umfasst dabei die Kommunikation wissenschaftlicher Inhalte, Ergebnisse oder Nachrichten innerhalb einer Fachcommunity, eines wissenschaftlichen Verbandes, Netzwerks, Projekts oder einer Institution. Die externe WissKomm unterscheidet die Kommunikation über Dritte (Wissenschaftsjournalismus) oder die Eigenvermittlung an verschiedene Publika (Politik, Öffentlichkeit usw.) zu verschiedenen Themen, mit verschiedenen Mitteln und verschiedenen Intentionen. Der Begriff “Podcast” setzt sich zusammen aus “pod” (“playable on demand”) und “cast” (von Broadcasting) und bezeichnet Audio-Sendungen (ferner auch Video- Sendungen) im Internet, die (im Unterschied zum klassischen Radio) jederzeit abrufbar sind. Wesentlich zu ihrer Verbreitung beigetragen haben RSS-Feeds in den späten 00er Jahren. Große Popularität erlangten wissenschaftliche Podcasts in Deutschland während der Corona-Pandemie – Vorreiter war insbesondere der Corona-Podcast des Virologen Christian Drosten (erste Episode vom 26.02.2020). Auch die wissenschaftliche Erforschung von Podcasts nahm in den letzten Jahren zu. Ein anderer Ansatz besteht darin, Interview-Podcasts als empirische Grundlage für die Entwicklung wissenschaftlicher Felder zu nutzen. Diesen Versuch unternimmt RaDiHum20 für die Digital Humanities: Über die verschiedenen Staffeln und Episoden hinweg wurde die Frage nach der Zukunft der Digital Humanities immer wieder gestellt, sodass ein Panorama möglicher Zukunftsvisionen der Digital Humanities entstanden ist. RaDiHum20 (“Radio Digital Humanities”, die “20” verweist auf das Gründungsjahr und das monatliche Erscheinungsdatum) ist ein Wissenschaftspodcast speziell für die Digital Humanities und den DHd-Verband. Er wurde in der ersten Jahreshälfte 2020 geboren und beteiligt waren und sind Jonathan D. Geiger, Lisa Kolodzie und Mareike Schumacher; Patrick Toschka verließ das Hostteam 2022, Nachfolger wurde Jascha Schmitz. Unterstützt werden sie mittlerweile von Clara Helmig. Mittlerweile sind insgesamt mehr als 70 Folgen in sechs Staffeln erschienen. Inhaltlich begleitet der Podcast nun schon die zweite DHd-Konferenz, interviewt Convenor*innen der verschiedenen Arbeitsgruppen des Fachverbandes und beleuchtet unter anderem Themen aus dem Bereich Wissenschaftsmanagement, Open Science und Wissenschaftskommunikation. Technisch setzt er insbesondere auf Discord und Zoom für die Aufnahmen, Audacity und Auphonic für die Audiobearbeitung sowie Wordpress und Mittwald für die Webseite und Kommunikation. Der Mastodonaccount hat über 200 Follower. Seit Einführung des Podcasts am 01.07.2020 wurden die Folgen insgesamt über 13.500 Mal angehört. Im Durchschnitt wurde jede Folge 190 Mal angehört. Rund 100 Abonnent*innen folgen RaDiHum20 über den Hosting-Service Podcaster.de, etwas mehr Follower*innen verzeichnet Spotify und 56 hören regelmäßig über Apple Podcasts zu. “Damals hieß DH in Deutschland eigentlich TUSTEP.” – Peter Gietz, S1E9, 20.04.2021 “Dann gab es den dritten Paradigmenwechsel (...), dass man sich plötzlich als weltweite Community versteht. Das ist mit dem Begriff Digital Humanities zu coinen.” – Peter Gietz, S1E9, 20.04.2021 “Ein wichtiger Impuls für die Gründung des Verbands war die Erkenntnis, dass die Community so weit ist, dass sie eine Institutionalisierung braucht, dass sie diese auch tragen kann und dass sie davon auch profitieren wird.” – Christof Schöch, S3E5, 20.06.2022 “Viele der Prozeduren [der Organisation der DHd-Konferenz], die heute normal sind, waren damals noch überhaupt nicht formalisiert.” – Elisabeth Burr, S6E2, 19.02.2024 “Ich sehe den DHd-Verband als Humus, aus dem ganz viele schöne Sachen wachsen können und die v | poster |
A first look into Gollum’s cave: Are we hoarding data because of legal uncertainties? Lea Sophie Singson (FIZ Karlsruhe), Jannes Uhlott (JKI), Constantin Bress (FIZ Karlsruhe), Sophie Boße (ZB MED), Anne Sennhenn (ATB Potsdam) We asked the agro science community a catalogue of questions regarding their experiences and reservations regarding the sharing of their data. Emphasis here was to gather insight from a legal perspective with questions surrounding the license landscape in institutions and familiarity of the community with licenses, the Good Scientific Practice and more. Here is what we know… We gathered that scientists are hesitant to publish research data, especially under a CC0 license or a public domain mark. One of the reasons for that seems to be the perceived risk of not being attributed by their peers. This was surprising, considering the participants also stated, that they are familiar with the Good Scientific Practice. It seems that although the name rings a bell, scientists do not know that the Good Scientific Practice forces attribution by other scientists. Also, the use of CC-BY licenses, which require citing, is widespread. In the survey, the scientists were asked if they had an understanding of what a CC-BY and a publication into the public domain legally means. The answers suggest that quite a few are confident in what the licenses do while many others either answered that they don’t know at all or that they are unsure. Those who answered “yes” or “I’m not sure” where then also asked to write down what exactly they think the licenses mean. Misunderstandings about the meaning of CC-BY seem to be common, however. Thus, training on data publication and licenses is required … and wanted! What do you think? Do you agree with this first look? Would you answer differently? Take the Survey! Get the Poster! | poster |
RESEARCH POSTER PRESENTATION DESIGN © 2015 www.PosterPresentations.com The Metadata Encoding and Transmission Standard (METS) is a metadata standard for encoding descriptive, administrative, and structural metadata for objects found in a digital library or archive. METS Preservation workflows for research data The Data Documentation Initiative (DDI) is a metadata standard for statistical and numeric data description. It is primarily used to describe social science research. DDI Preservation Metadata: Implementation Strategies (PREMIS) is a useful vocabulary and set of defining attributes to describe preservation actions and events needed by preservation repositories and systems. PREMIS AIP Archival Information Package (AIP) is conceptual information package for digital objects in a Open Archival Information System (OAIS). BagIt is a standard developed by the Library of Congress used to represent an AIP. AIP Structure ├── data │ ├── logs [log files generated during processing] │ │ ├── fileFormatIdentification.log │ │ └── transfers │ │ └── NADDI2017a0f309a-d3ec-43ee-bb48-a868cd5ca85c │ │ └── logs │ │ ├── extractContents.log │ │ ├── fileFormatIdentification.log │ │ └── filenameCleanup.log │ ├── METS.dfb0b75d-6555-4e99-a8d8-95.xml [AIP METS file] │ ├── objects [a directory w/digital objects being preserved, + metadata] │ ├── NADDI2017.jpg [an original file from Dataverse] │ ├── NADDI2017.sav [an original file from Dataverse] │ ├── NADDI2017 [a bundle retrieved from Dataverse] │ │ ├── NADDI2017.xml [DDI XML] │ │ ├── NADDI2017.ris │ │ ├── NADDI2017.xml │ │ └── NADDI2017.tab [TAB derivative file generated by Dataverse] │ ├── metadata │ │ └── transfers │ │ └── NADDI2017a0f309a-d3ec-43ee-bb48-a868cd5ca85c │ │ ├── agents.json [data source agent in the AIP METS file] │ │ ├── dataset.json [full json file retrieved from Dataverse] │ │ └── METS.xml [METS file generated by Archivematica] │ └── submissionDocumentation │ └── transfer-58-1a0f309a-d3ec-43ee-bb48-a868cd5ca85c │ └── METS.xml [standard transfer METS file w/all contents] AIP structure adapted from: Archivematica Wiki. 2017. https://wiki.archivematica.org/Dataverse https://creativecommons.org/licenses/by-sa/3.0/ Ontario Library Research Cloud (OLRC) Amber Leahey | Data and GIS Librarian Scholars Portal | amber.leahey@utoronto.ca Data curation that follows best practices in digital preservation can ensure that research data are actively managed for reproducibility and reuse by others, well into the future. Metadata for Research Data Preservation in Libraries / Archives METS Structure Full Mid Basic Format Identification ü ü No Normalization ü No, basic checks performed No, basic checks performed Example JPEG to TIFF, storing original JPEG SPSS, SAS and ArcGIS files STATA and MATLAB files What does it do? • Creates archival information packages (AIP) using best practice standards such as LC BagIt, METS, and PREMIS • Performs file identification, validity checking, and normalization based on Format Policy Registry (FPR) • Manage processing and storage transfer of AIPS for long-term preservation. What doesn’t it do? • Provide a transfer interface for data and metadata from researchers • Provide working storage for researchers • Register DOIs or report holdings to data registries • Manage retention periods and policies • Generate statistics for usage / access Dataverse Metadata Data Provenance and Preservation Events <mets:mets xsi:schemaLocation=http://www.loc.gov/METS...> <metsHdr CREATEDATE=“2017-31-03T15:00:00" STATUS="Complete"> ßSection for descriptive metadataà <mets:dmdSec CREATED=“2017-31-03T15:00:00” ID=“dmdSec_859112” STATUS=“original” > <mets:mdWrap MDTYPE=“DDI”> <mets:xmlData> <ddi:codebookversion=“2.5” xsi:schemaLocation=“URL”> <ddi:stdyDscr> <ddi:citation> <ddi:titleStmt> <ddi:title>NADDI2017 Rocks!</ddi:title> <ddiIDNo agency=“doi”>10.5072/SP/OGHTIM</ddiIDNo> </ddi:titleStmt> </mets:xmlData> </mets:mdWrap> </mets:dmdSec> <mets:dmdSec CREATED=“2017-31-03T15:00:00” ID=“dmdSe | poster |
Flat galaxy rotation curves Flat galaxy rotation curves naturally follow from dark matter filaments naturally follow from dark matter filaments Felipe J. LlanesEstrada Felipe J. LlanesEstrada Dept. Física Teórica & IPARCOS Dept. Física Teórica & IPARCOS Univ. Complutense de Madrid Univ. Complutense de Madrid Abstract Spiralgalaxy v(r) rotation curves look flat (constant v) unlike Kepler's 3rd law in 3dim. They are however natural in 2 dimensions. In our world, this is achievable with cylindrical symmetry. If cosmological scale filaments extend to galactic scale, the velocity will be constant indefinitely; if instead there are dark matter haloes which are prolate, eventually v(r) should be observed to decrease with r. ✔ Further reading: preprint DOI: 10.13140/RG.2.2.35022.41289 ✔Work supported with funding by grant MINECO:FPA201675654C21P (Spain) & UCM under research group 910309 and its Institute for Particle and Cosmological Physics (IPARCOS) Want to listen to it? https://youtu.be/5nxy38gXEyQ Want to listen to it? https://youtu.be/HvZhCvnuJYY Spiral galaxy rotation curves Unlike Kepler's are flat 3rd planetary law Vera Rubin et al. Astron.J. 118 (1999) 236260 SPARC data 1 2 1 3 4 Presented at the virtual conference “Galaxy Formation and Evolution in the Era of the Nancy Grace Roman Space Telescope” October 5th9th 2020 based on preprint DOI: 10.13140/RG.2.2.35022.41289 One conventional explanation: spherical dark matter haloes Weber and de Boer, A&A 509, A25 (2010) Fits to simulations give profiles that only momentarily look isothermal (exponent = 2) Additionally, cuspcore problem isothermal profile v(r) = constant (sketch by CTA observatory) Dark matter remains hidden and not for lack of searching Want to listen to it? https://youtu.be/s0AtB0iSCfU 2nd conventional explanation: MOND (Modified Newtonian Dynamics) My two pence: v(r) is constant if the source is not spherical, but rather cylindrical (But how would uninteracting dark matter thermalize?) TullyFisher: unexpected correlation between luminosity (ordinary matter) & rotation velocity (dark matter) Baryonic TullyFisher relation: Want to listen to it? https://youtu.be/nNecI7RLes An exponent 4 is exactly predicted by MOND, that is constructed to explain rotation curves: by lowering the acceleration (taking its geometric mean with a constant) it is in effect lowering one dimension of r. A bit distasteful: Newton and Gauss's theory is very compelling and we have 3 dimensions, not 2. Additionally, MOND runs into largescale cosmological problems. F~1/r implies v= √(2Gλ)=constant (λ is the linear mass density) R Adding a sphere (normal matter) to the filament: Cylinder thickness? Compelling 0th order physics! 4 7 5 What if…? Observational consequences Want to listen to it? https://youtu.be/QcisEL6Eh70 Want to listen to it? https://youtu.be/NAOgvuOhkBg Want to listen to it? https://youtu.be/sK0rW1TF10 6 Prolate Prolate dark matter haloes also flatten v(r), but not indefinitely Finite dark matter cylinder |z|< a Y. Sofue arXiv: 1504.05368 Vega-Ferrero, Yepes, Gottlöber, arXiv:1603.02256 DM simulations yield more prolate than oblate haloes Observational question: Observational question: can one establish that can one establish that break for spiral galaxies break for spiral galaxies (prolate haloes) or is v(r) (prolate haloes) or is v(r) indefinitely flat (filaments)? indefinitely flat (filaments)? TullyFisher baryon relation DM: search @ high latitude Imaging with grav. lensing: stacking galaxy pairs shows DM filament between next neighboors (not otherwise) Epps, Hudson, MNRAS. 468 2017 Helicoidal motion along a cylinder *Synchrotron radiation is small for finite R *Galactic aurora (Fermi bubbles?) What if…? Observational consequences Precession of orbital plane of objects outside disk M. Pawlowski arxiv 1802.02579 Accretion along narrow filaments could explain Milky Way anisotropic satellite distribution Virial theorem for small galaxy clusters threaded by orie | poster |
Further Reading General Info ● Arbetarrörelsens Arkiv och Bibliotek - https://www.arbark.se/ ● Folkrörelsearkivet för Uppsala Län - https://www.fauppsala.se/ ● Archiv der sozialen Demokratie - https://www.fes.de/archiv-der-sozialen-demokratie ● International Institute of Social History - https://iisg.amsterdam/ ● Riksbankens Jubileumsfond - https://www.rj.se/ ● Grant Information - https://www.rj.se/en/grants/2020/labours-memory.-digitization-of-annual-and-financial -reports-of-blue-collar-worker-unions-1880-2020/ Technology ● International Image Interoperability Framework (IIIF) - https://iiif.io/ ● Omeka S - https://omeka.org/s/ ● Archival IIIF server - https://github.com/archival-IIIF/server ● Archivematica - https://www.archivematica.org/ ● Archival Resource Key (ARK) - https://arks.org/ ● handle - http://www.handle.net/ ● Named Entity Recognition: Crina Tudor and Eva Pettersson. 2024. People and Places of the Past - Named Entity Recognition in Swedish Labour Movement Documents from Historical Sources. In Proceedings of the 8th Joint SIGHUM Workshop on Computational Linguistics for Cultural Heritage, Social Sciences, Humanities and Literature (LaTeCH-CLfL 2024). https://aclanthology.org/2024.latechclfl-1.17 ● Handwritten Text Recognition: "Loghi" - https://github.com/knaw-huc/loghi | poster |
In conclusion, the most efficient AOP for the inactivation of the bacteria studied is the combined UV-Chlorine process. However, the degradation of chlorine during the photolysis processes has been measured, the final free chlorine concentration has always been higher than 0.02 ppm, taking into account that the concentration of toxic chlorine becomes visible for concentrations higher than this value for the health of the aquatic environment, an active carbon filter should be installed before introducing the regenerated water into the aquaponic system. INTRODUCTION METHODOLOGY RESULTS CONCLUSIONS Some of the most effective methods used are Advanced Oxidation Processes (AOP), where oxidants such as hydroxyl radicals are formed to oxidize organic contaminants and microorganisms. Among these methods, the combination of ultraviolet radiation (UVC) with oxidizing agents such as chlorine or hydrogen peroxide (H2O2) stands out. This study focuses on bacterial inactivation in water for reuse purposes using UVC/Cl and UVC/H2O2 AOPs, forming mainly hydroxyl free radicals and chlorine, in a small-scale reactor. The use of oxidizing agents is supposed to increase the efficacy of this process to be applied as a tertiary treatment in a sewage treatment plant. INACTIVATION OF E. COLI AND ANTIBIOTIC RESISTANCE BY UVC/CHLORINE FOR THE FEEDING OF AQUAPONIC SYSTEMS WITH REGENERATED WASTEWATER. Molina Ramírez, María Dolores; Pablos Carro, Cristina; Marugán, Javier Department of Chemical and Environmental Technology, ESCET, Universidad Rey Juan Carlos, C/Tulipán s/n, 28933 Móstoles, Madrid, Spain. E-mail: mariadolores.molina@urjc.es G Grupo de Ingeniería Química y Ambiental ACKNOWLEDGEMENTS: The authors are grateful for the financial support of the Ministry of Science and Innovation through the AquaEnAgri Project (2022/00305/017) and the Horizon Europe Framework Program (HORIZON-CL6-2022-FARM2FORK-01, through AWARE Project, GA N. 101084245. Recirculating aquaculture systems (RAS) involves the accumulation of waste products and microbial load. To maintain optimal growth of plants and fish in aquaponics, filtration and contaminant removal systems must be implemented. A RAS advantage is the reduction of water requirements compared to raceway or pond aquaculture systems.. To go further and for this purpose, this work has evaluated the efficacy of photolysis process in bacterial inactivation with the goal of being applied as a regenerated wastewater treatment to be reused in the aquaponics system. In the case of E. coli inactivation processes, the kinetic constant increases linearly with irradiance and chlorine concentration. However, in the non-irradiated chlorination processes during ARB (Van) inactivation, no further degradation is observed with increasing chlorine concentration. This shows that the use of UV-C radiation is necessary to degrade this type of contaminant. Residual free chlorine at the end of each experiment comprises values between 0.06 and 0.09 ppm, at an initial chlorine concentration of 0.1 ppm and values of 0.06 and 0.17 ppm for an initial concentration of 0.25 ppm, depending on the light conditions. In the case of UV-H2O2 processes, they have shown to be less effective resulting in lower and similar kinetic constants despite the increase in concentration of the compound. TESTS Pollutants • Escherichia coli • Resistant bacteria to the antibiotic Vancomycin (ARB-Van) Kinetic constants calculation (k) Log (CFU/mL) = k · t (min) Oxidizing compound (ppm) Free chlorine Hydrogen Peroxide 0.1 20 0.17 50 0.25 0.5 UVC (254 nm) Radiation (W/m2) 2.89 4.79 7.89 34.42 82.41 0 5 10 15 20 25 30 0 10 20 30 40 k (min-1) Rad (W/m2) E. coli, UV-Cl Process 0 ppm 0.1 ppm 0.25 ppm 0 1 2 3 4 5 6 0 10 20 30 40 k (min-1) Rad (W/m2) E. coli, UV-H2O2 Process 0 ppm 20 ppm 50 ppm 0 5 10 15 20 25 30 0 10 20 30 40 k (min-1) Rad (W/m2) ARB (Van), UV-Cl Process 0 ppm 0.1 ppm 0.25 ppm 0 1 2 3 4 5 6 7 8 0 10 20 30 40 k (min-1) Rad (W/m2) ARB (Van), UV-H2O2 Process 0 | poster |
Do camel types exhibit geometric variation in torso shape? Insights from social media Randa Alaqeely, Hasan Alhaddad, and Bader H. Alhajeri Department of Biological Sciences, Kuwait University, Kuwait Introduction • Camels have unique morphological and behavioral adaptations to deserts that make them scientifically and culturally important. • There are different camel ‘types’, including groups bred for racing, others for milk production, as well as types bred for various other purposes. • Each camel type is characterized by certain features, such as a particular coat color and texture, unique hump position, as well as distinctive limb dimensions. • Few studies use detailed morphometric measurements to assess the extent and the direction of variation across camel types; to our knowledge, none use geometric morphometric data to assess this variation. • We obtained images of various camel types from various camel breeder social media accounts, which we use to quantify overall shape variation across types. • We assessed torso shape variation based on a sample of 2D landmarks— homologous anatomical loci—analyzed using geometric morphometrics. Objectives 1. Identify 12 landmarks that adequately capture overall torso shape. 2. Study shape variation across camel bodies using image-based geometric morphometrics—a method that generates size-independent shape variables that can be used to assess variation in camel types. Materials and Methods 5. Results Acknowledgments: This project would not have been possible without images posted by camel breeders on their social media accounts, including: ime1111, hjn_uae, alotaibi_654, smsrbywshr, djekv493hf, rashed1209, ahmedreshidi, aljhaam, 3lag_al7lal, camel.kw, theking2050, al_nahab, alsultan38, nsas669, zmool_alarab, o.77_, osaamah23, _a_qatar_9033, shr2222, swaihaan). • Camel images (n = 104) were acquired from publically available camel breeder social media accounts. Only photographs in which camels were positioned parallel to the camera plane were retained and analyzed. • The chosen camel photographs represent seven camel types (Onafi, Omani, Sudani, Mejaheem, Maghateer, Kenani, and Pakestani (Fig.1). • Six dorsal and six ventral torso landmarks were digitized in a standardized manner (Fig.2). • Landmark coordinates were then subjected to generalized procrustes analysis (GPA), in order to obtain size-independent shape variables (procrustes coordinates), that were used to compare camel type shapes. • Shape variation was then summarized to a smaller set of variables by performing principal component analysis on the procrustes coordinates. • The retained principal components (determined by the broken-stick criterion) were then visualized using a boxplot (PC1), with the individual camels divided based on type(Fig.3). • The magnitude of the differences in torso shape among the geometric mean of each camel type were visualized using the UPGMA clustering method (based on Euclidean distance) (Fig.4); the locations of the aforementioned differences were visualized using thin-plate spline deformation grids (Fig.5). Conclusion 1. We were successful in quantifying overall torso shape variation among camel types based on images extracted from social media. 2. While at this point we can conclude that overall torso shape among camel types does vary, the statistical significance of this variation needs to be assessed after the dataset sample size is increased. @jamalid_report jamalidreport@gmail.com @jamalidreport Fig.5: Thin-plate spline deformation grids. These grids depict the main shape differences between the consensus landmark configuration of each camel type vs. the consensus landmark configuration of the whole sample (all camel types combined, shown in the center). ONF KNN MJH SUD MGH PAK OMN Mezayen Racing Pakistani Kenani Majaheem Sudani Omani Onafi Omani Maghateer Fig.4: Phenograms resulting from the unweighted pair-group method with arithmetic mean (UPGMA) cluster analysis. UPGMA was performed | poster |
Statement of need Collec'ng, aggrega'ng, and analyzing data to produce metrics is easier than ever before. In the realm of academic research, data on the digital distribu'on of scholarly content provides new opportuni'es to understand the publishing ecosystem. A range of stakeholders currently generates and collects this data, o?en as products of content usage or sales. There is growing concern about the ownership of, access to, and analysis of this data for “predic've bibliometrics.” Despite the growing demand for rich data and predic've analy'cs, the high costs of providing or purchasing data-‐ related services are reinforcing inequi'es in the academic publishing landscape. Furthermore, the challenges associated with gathering, integra'ng, interpre'ng, and repor'ng usage data limit the ability of individual publishers, libraries, and other stakeholders to iden'fy— much less predict—important usage trends and opportuni'es through which these organiza'ons might extend their impact. Based on ins'tu'onal contribu'ons that would be used to seed-‐fund this project (at $1K and $5K levels), Project Meerkat will gather a diverse community of scholarly communica'on stakeholders, including authors and editors, to jointly develop governance, sustainability, and ethical frameworks for how usage data is gathered, analyzed, and shared, building upon the NISO Privacy Principles. The project team will also scope and develop analy'c and benchmark reports to meet the iden'fied needs of libraries, publishers, aggregators, and other stakeholders. The resul'ng Publishing Analy'cs Data Alliance will work to sustain the outcomes of Project Meerkat, providing its members with shared governance of collected data. Member organiza'ons will agree to a code of prac'ce as a condi'on of membership. Developing tools and protocols rela5ng to the collec5on, aggrega5on, and dissemina5on of usage data about digital monograph publica5ons A Publishing Analy'cs Data Alliance We invite publishers, libraries, research centers, socie7es, funders, aggregators, and other scholarly communica7on stakeholders to join Project Meerkat to develop guidelines and standards for digital scholarly monograph usage data and to construct a neutral organiza7onal apparatus for the ongoing collec7on and aggrega7on of data about these scholarly publica7ons. Current conveners for Project Meerkat Chris7na Drummond (Educopia Ins'tute) Mar7n Paul Eve (Birbeck, University of London & Open Library of Humani'es) Kevin Hawkins (University of North Texas) Sarah Melton (Emory University) Lucy Montgomery (Cur'n University & Knowledge Unlatched) Cameron Neylon (Cur'n University) Lisa Schiff (California Digital Library) Katherine Skinner (Educopia Ins'tute) Es7mated budget Project Meerkat (2017–2020): $480,500 To cover the costs of project facilita'on, development, and in-‐person convenings of experts to complement virtual working groups. Publishing Analy7cs Data Alliance (2020 forward) On-‐going revenue streams will be established to cover the costs associated with con'nued support of shared infrastructure and services. | poster |
U.S. Quantum Information Science School Micro-scale Types of Models Superfluidity Mathematical Analysis of Models of Superfluids Pranava Chaitanya Jayanti Department of Mathematics, University of Southern California Formerly: Department of Physics, University of Maryland Conversion between normal and superfluid phases with changing temperature. Adapted from [Vinen 2004]. Phase diagram of He-4. “Liquid II” = Superfluid. Adapted from [Young 1975]. D = integral length scale; l = inter-vortex spacing; 𝛏 = vortex core radius. Taken from [Jayanti 2022] Macro-scale • D A Young. Phase diagrams of the elements. Technical report, Lawrence Livermore National Lab, 1975. • W F Vinen. The physics of superfluid helium. Technical report, CERN, 2004. • P C Jayanti. Analysis of models of superfluidity. Doctoral dissertation, University of Maryland, 2022. • P C Jayanti, K Trivisa. Local existence of solutions to a Navier-Stokes-Nonlinear-Schrödinger model of superfluidity. J. Math. Fluid Mech., 2022. • P C Jayanti, K Trivisa. Uniqueness in a Navier-Stokes-Nonlinear-Schrödinger model of superfluidity. Nonlinearity, 2022. • J Jang, P C Jayanti, I Kukavica. Small-data global existence of solutions for the Pitaevskii model of superfluidity. arXiv, 2023. • J Jang, P C Jayanti, I Kukavica. Small-data global existence for the Pitaevskii model of superfluidity in 3D. In prep, 2023. • P C Jayanti, K Trivisa. Global Regularity of the 2D HVBK Equations. Journal of Nonlinear Science, 2021. q Most fluids are described by the Navier-Stokes equations (NSE) q Exhibit viscosity: microscopic roots in the entropic drive for particles to exchange momentum and achieve equilibrium, manifesting as dissipation at macroscopic length scales q Superfluids like Helium-4 are fundamentally inviscid: all the particles move in unison q Bose Einstein condensation below 𝑇! ≈2.17𝐾 for He-4 q Superfluid vorticity – discrete filaments, quantized circulation q He-4 (bosonic) and He-3 (fermionic) both display remarkable properties: critical velocity, film flow, fountain pressure q 𝑇= 0: Pure superfluid; 𝑇> 0: Part of normal liquid condenses into the superfluid q Essential to model and quantify the retarding interactions between phases Pitaevskii 𝜕!𝜓+ 𝜆𝐵𝜓= −1 2𝑖Δ𝜓+ 𝜇 𝑖𝜓"𝜓 𝐵= 1 2 −𝑖∇−𝑢# + 𝜇𝜓" 𝜕!𝜌+ ∇⋅𝑢𝜌= 2𝜆ℜ𝜓𝐵𝜓 𝜕! 𝜌𝑢+ ∇⋅𝜌𝑢⊗𝑢+ ∇𝑞= 𝜈Δ𝑢−𝛼𝜌𝑢−2𝜆ℑ∇𝜓𝐵𝜓 ∇⋅𝑢= 0 Hall-Vinen-Bekarevich-Khalatnikov ∇⋅𝑢$ = 0, ∇⋅𝑢% = 0 𝜕!𝑢$ + 𝑢$ ⋅∇𝑢$ + ∇𝑝$ = 𝜈$Δ𝑢$ + 𝜌% 𝜌𝐹 𝜕!𝑢% + 𝑢% ⋅∇𝑢% + ∇𝑝% = 𝜈%Δ𝑢% −𝜌$ 𝜌𝐹 𝐹= −𝐵 2 𝜔% 𝑢$ −𝑢% + 𝐵& 2 𝜔% 𝑢$ −𝑢% ' q Proposed by Pitaevskii in 1959 to model interacting dynamics between superfluid (nonlinear Schrödinger) and normal fluid (Navier-Stokes) q Order parameter 𝜓 describes superfluid; density 𝜌 and velocity 𝑢 characterize normal fluid q Both phases interact through bidirectional, nonlinear coupling operator 𝐵, consisting of relative kinetic energy and potential self-interaction q Normal fluid velocity taken to be divergence-free: incompressible, inhomogeneous fluid q For small data, global-in-time existence of weak solutions established for both 2D and 3D when 𝑝< 4, and exponentially/polynomially long existence time for 2D when 𝑝≥4 [Jang, Jayanti, Kukavica 2023] q Weak-strong uniqueness of solutions also studied [Jayanti, Trivisa 2022] q Main difficulty in analysis stems from sign-indefinite source in the continuity equation – converts superfluid into normal fluid (on average) q Ignore vortex dynamics and relaxation – continuous vorticity field q Assume both fluids classical, and add a nonlinear coupling q Useful when high density of vortex filaments are aligned (2D) q Studies on instability of superfluid Taylor-Couette flow, and quantum turbulence q Dealing with high frequencies: suppress in 𝑢", subgrid modeling like LES, or artificial viscosity q For 2D, system is globally-in-time well-posed: unique, smooth solutions with continuous dependence on initial data [Jayanti, Trivisa 2021] q Current work is on investigating system for analytic-in-time, Gevrey-in-space solutions (subset | poster |
PathoScope: a multi-omic approach to characterize microbiomes and identify pathogens Castro-Nallar E.1, Shen Y.2, Freishtat R.J.3, Pérez-Losada M.1, Manimaran S.2, Liu G.2, Spira A.2, Johnson W.E.2, and Crandall K.A.1 1Computational Biology Institute, George Washington University, Ashburn, VA 20147; 2Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA 02118; 3Division of Emergency Medicine, Children’s National Medical Center, Washington, DC 20010 INTRODUCTION • The human microbiome plays a key role in a variety of human health issues from obesity to respiratory disease (Huang et al., 2013). • Assessing taxonomic and functional diversity of microbiomes across time, individuals, and tissues within individuals is crucial to understand infection and disease. • The affordable costs of high-throughput sequencing (HTS) and the limitations of single gene inferences, are pushing microbiome studies towards shotgun metagenomics. • Identifying causal pathogens and characterize microbiomes in metagenomic studies is a daunting task due to the large volume of data generated. • A variety of techniques have been developed to isolate potential pathogens for HTS targets using molecu lar biological approaches. However, this limits the inferences with respect to the host response. • We developed a computational solution combining metatranscriptomic microbial identification and host differential gene expression signatures. • We applied this approach to identify pathogens associated with pediatric asthma. METHODS Sample Collection Nasal epithelial cells from the nares were collected from 8 children with asthma and 6 controls. Participants were part of the Asth MaP (Asthma Severity Modifying Polymorphisms) Project at Children’s National Medical Center. Total RNA was extracted using Trizol (Life Technologies) reagent and puri fied in silica columns (Ambion, Carls bad CA). Total RNA was subjected to RiboZ ero ribosomal RNA reduction prior to library preparation using Illumina TrueSeq Stranded Total RNA kit (San Diego, CA) and sequenced on a HiS eq 2500 instrument on two separate ‘Rapid’ flow cells. Analyses Reads were preprocessed using PrinSeq-Lite and PathoQC (trim ming reads and bases < 25 PHRED). Target and filter genome libraries were built in PathoLib. Reads were aligned using Bowtie2 (Langmead and Salzberg, 2012) and filtered against the human genome (hg19) using PathoMap. The microbial communities in each patient were then characterized in PathoID. Raw counts identified in Pa thoScope were normalized using regularized-log transformation in DESeq2. Taxa abundance was tested us ing a negative binomial Wald test also as in DESeq2. Plots were created in R using Phyloseq, ggplot2, gplot packages. Gene differential expression analysis were performed in TopHat (Kim et al., 2013) and Cufflinks (Trapnell et al., 2012). Host response gene expression signatures between groups were compared in PathoSig using an adaptive Bayesian factor analysis model. CASE STUDY: ASTHMA IN CHILDREN Metatranscriptomic microbial identification • RNA-Seq runs generated an average of 41.4 million single-end 100bp sequencing reads per sample: 90- 95% human and 5-10% microbial. • Five of the 8 cases showed a high prevalence of the bacterial species Moraxella catarrhalis and Moraxella nonliquefaciens, while controls showed low prevalence. • These findings confirm previous metagenomic surveys which found large proportions of Proteobacteria in cases but not controls, speculating that this could be explained by Moraxella spp. and Hemophilus spp. (Hilty et al., 2010). PathoLib Raw Sequencing Reads (fastq) Quality Controlled Reads (fastq) NCBI nucleotide database (fasta) Host, Filter, and Target Genome Libraries (fasta) Filtered Read Alignments (sam) Reassigned Read Alignments (sam) Detailed Report (xml) 2. PathoMap 4. PathoID 5. PathoReport 6. PathoDB 1. PathoQC 3. PathoDB Core Module Optional Module Modules 1. PathoDB A mysql database con | poster |
CSSI Frameworks: Re-engineering Galaxy for Performance, Scalability and Energy Efficiency Award #: OAC-1931531 NSF CSSI PI Meeting, Seattle, WA, Feb. 13-14, 2020 II. Our Objective Re-engineer the Galaxy framework to enable GPUs and accelerators like FPGAs as "first-class" compute engines. Enlarge the Galaxy community by bringing GPU and FPGA supported tools. Enable Galaxy tools to take better advantage of emerging cluster scheduling capabilities. Achieve significant improvements in performance scalability and energy efficiency. I. What is the Problem? Galaxy is an open source, web-based framework that is extensively used by more than 20,000 researchers world-wide in many areas. Current galaxy implementation does not support GPU and accelerators like FPGAs. There is no support for dynamic resource scheduling and management in Galaxy. Galaxy Centers Galaxy Popularity IV. Current Developments Identified existing GPU based tools such as Racon. Integrated a GPU based implementation of RACON, a genomic consensus tool to Galaxy Toolshed . Integrated a GPU-version of Smith- Waterman sequencing tool to Galaxy. Deployed Galaxy on a Kubernetes managed cluster. V. Next Steps Develop GPU based implementation for existing ML tools for RNN sequencing, using Keras framework. Use GPU plugin in Kubernetes to enable GPU access for Galaxy pods. Expose GPU metrics to develop resource utilization-aware scheduling policies. Develop a Reinforcement-based Machine Learning scheduling framework. Develop a distributed data-store using Rook, to enable near data placement based scheduling policies. https://galaxyproject.org Get in Touch: mtk2@psu.edu Acknowledgments: Galaxy project is also supported by NSF grant #1661497 and other NIH grants. III. Our Vision for Galaxy 300k page views Deployed in 128 platforms 8915 publications > 7 million Research funds > 7800 supported tools 10000+ online subscribers 8000+ twitter followers Learn More PI: Mahmut Taylan Kandemir *, Co-PIs: Chita R. Das *, Anton NekrutenkoΨ, Paul Medvedev * * Dept. of Computer Science and Engineering, Ψ Dept. of Biochemistry and Molecular Biology Institution: The Pennsylvania State University, University Park | poster |
Fairness wird mit Fairness-Metriken gemessen, die auf einer binären Einteilung beruhen. Um Fairness zu messen, muss Techie entscheiden, welche Gruppen verglichen werden sollen. Techie tut dies, indem sensible Merkmale (sensitive attributes) definiert und die Testdaten in zwei Gruppen aufgeteilt werden: privilegiert und nicht privilegiert. So kann Techie feststellen, ob sich das KI-Modell für verschiedene Gruppen unterschiedlich verhält. für vordefinierte Merkmale wie Geschlecht, Ethnie und sexuelle Orientierung. Sensible Merkmale Privilegiert (A) z.B. Menschen, die als männlich, weiß, nicht-queer gelesen werden Nicht-privilegiert (B) Ich fühle mich unwohl, Geschlecht, Ethnie und sozio- ökonomischen Status von Menschen auf Basis ihrer Daten anzunehmen... gruselig! Aber ich sehe keine andere Möglichkeit, um systemische Ungerechtigkeit zu erkennen... Für jedes Attribut erstellt Techie eine Tabelle für die privilegierten (A) und die nicht-privilegierten (B) Gruppen. Sie zeigt, wo das Modell korrekt prognostiziert hat und wo nicht. Durch den Vergleich dieser Zahlen wird deutlich, ob das Modell für privilegierte oder nicht-privilegierte Gruppen genauer ist. Fairness durch Unawarness Fairness bedeutet, dass sensible Merkmale bei der Entscheidungsfindung nicht explizit berücksichtigt werden. Treatment Equality Das KI-Modell ist fair, wenn: Das KI-Modell ist fair, wenn: Biases und Unfairness sind überall – wie kann Techie sicherstellen, dass deren KI-Modell fair ist? Fairness wird als Gleichbehandlung verschiedener Gruppen beschrieben. Das kann jedoch unterschiedlich interpretiert werden. Fairness durch Awareness Fairness bedeutet, dass ähnliche Personen unabhängig von ihrer Gruppe ähnlich eingeordnet werden. Demographic Parity Was denkst du ist fair? Was empfindest du als fair? Welcher der Ansätze hat dich überzeugt? Stimme mit einem Sticker ab! Intersektionaler Ansatz: Fairness bedeutet, dass wir Machtverhältnisse verschieben und Prozesse teilen. Sie zu quantifizieren ist weder möglich noch hilfreich. Es gibt viele verschiedene Fairness Metriken - welche ist die beste? Hier sind einige Beispiele: Fairness bedeutet, dass beide Gruppen dieselbe Wahr- scheinlichkeit haben, akzeptiert zu werden: 40% der Bewerber*innen sind weiblich – 40 % der neu Eingestellten sollten weiblich sein! Das Verhältnis zwischen den fälschlicherweise abgelehnten und den fälschlicherweise eingestellten Personen ist in etwa gleich groß. Fairness bedeutet, dass sich Fehler des KI-Modells auf beide Gruppen in ähnlichem Maße auswirken. Fairness-Metriken basieren auf binären Kategorien und erschweren die Berücksichtigung der Nuancen verschiedener Lebensrealitäten. Es gibt zwei Ansätze für Kritik an ihnen: Genauigkeitsbezogener Ansatz: Individuenbezogene Fairness metriken Feels fair? Wirken sich Fehler stärker auf eine Gruppe aus? Gruppenbezogene fairness metriken Bias zu reduzieren, bedeutet, Datensätze zu verändern. Diese Veränderungen könnten zu mehr Fairness, aber auch zu geringerer Genauigkeit führen. Es muss einen Abwägungsprozess geben, welche Kriterien angestrebt werden. Der Versuch, Bias zu verringern, macht KI- Modelle weniger genau. Genauigkeit Fairness Die Verwendung von Metriken zur Messung von Fairness ist zu eindimensional. Klasse, Geschlecht oder Ethnie sind nicht binär, sie überschneiden und überlappen sich. Fairness – die Gleichbehandlung verschiedener Gruppen – ist nicht immer der richtige Ansatz. Wenn es um Gerechtigkeit geht, dann muss Gerechtigkeit im Sinne gleicher Zugangsmöglichkeiten (Equity) eine Rolle spielen. Wichtiger als Metriken ist Anerkennung: Haben die betroffenen Menschen ein Mitspracherecht in den Prozessen? Alle Positiven Alle Alle Positiven Alle ≈ Gruppe A: Gruppe B: Falsch Negativ Falsch Positiv Falsch Negativ Falsch Positiv ≈ Gruppe A: Gruppe B: z.B. Menschen, die als nicht- männlich, nicht-weiß, queer gelesen werden Fairness entzieht sich Metriken wahr POSITIV FALSch NEGATIV FALSch POSITIV Wahr NEGATIV KI prognostiziert: einst | poster |
Multiphase Fluid-Structure Interaction Software Infrastructure to Enable Applications in Medicine, Biology, and Engineering Boyce E. Griffith1, Amneet P. S. Bhalla2, M. Gregory Forest1, Matthew G. Knepley3, and Neelesh A. Patankar4 1University of North Carolina at Chapel Hill, 2San Diego State University, 3University at Buffalo, and 4Northwestern University NSF Awards OAC 1931516 (UNC-Chapel Hill), OAC 1931372 (Northwestern), OAC 1931368 (SDSU), and OAC 1931524 (UB) ibamr.github.io OVERVIEW Coupled fluid-structure systems are ubiquitous in biology, physiology, and medicine, and these systems occur across a broad range of spatial scales: • writhing and coiling of DNA; • beating and pumping motions of cilia and flagella; • flow of blood in the heart and throughout the circulation; • swimming bacteria and fish, and flying birds and insects; • fluttering of leaves and dispersal of seeds and pollen by the wind. Fluid-structure interaction is also common in engineering applications. The immersed boundary (IB) method is an approach to to fluid-structure inter- action (FSI) that uses: • an Eulerian description of the momentum and incompressibility of the fluid-structure system; and • a Lagrangian description of the structural stresses, forces, and deformations. The IB approach to FSI: • facilitates the use of fast Cartesian grid solvers; • reduces or eliminates the need for dynamic regridding; and thereby • enables simulations with very large deformations/displacements. IBAMR is a C++ framework for FSI models based on the IB method. IBAMR provides support for Cartesian grid (structured) adaptive mesh refine- ment (AMR). Support for Lagrangian (unstructured) AMR is planned. Cartesian grid AMR allows high spa- tial resolution to be deployed only where needed (e.g. near the immersed bodies): IBAMR also enables numerical methods research, including work on Lagrangian- Eulerian coupling schemes, time-stepping algorithms, and fast solvers. IBAMR IBAMR provides modular structural de- scriptions to enable a range of models: • systems of springs and beams; • nonlinear elasticity; • peridynamics; • elastic rods; and • rigid structures and bodies with prescribed kinematics. This project is extending IBAMR’s multiphase fluids capabilities and en- hancing its Lagrangian-Eulerian coupling schemes, geometrical model representa- tions, and parallel performance. Recent methodological enhancements include: • efficient Brinkman penalization-based coupling; • polymeric fluid models; • one-sided IB coupling operators; • immersed interface method (IIM) coupling; • IIM-based schemes for rigid-body and flexible-body FSI; and • cut cell-based methods for advection-reaction-diffusion models in moving domains. IBAMR project milestones include: • six-month release cycle since 2018; • ≥460 unit and integration tests; • new CMake-based build system; • improved support for CI to automatically run tests on multiple platforms; • autoibamr: automatically compile and install IBAMR and its dependencies; • new algorithms for parallel IB data partitioning and load balancing; and • used in ≥130 peer-reviewed publications, ≥30 graduate and undergraduate theses. 2018 2019 2020 2021 2022 2023 0 100 200 300 400 500 600 700 800 900 1000 Total Execution Time, s libMesh deal.II Benchmark performance of IBAMR’s IBFE nonlinear elasticity FSI scheme with different finite element libraries. MAJOR ENHANCEMENTS Advection and diffusion of chemical species in moving subdomains with Robin boundary conditions that convert from one concentration to the other along the moving interface. Melting and solidification of an aluminum block with trapped gas. Porosity defect in metal 3D printing. Colors: yellow (solid Al), blue (molten Al), white (gas). Light rigid sphere rising in a water column via a new IIM-based sharp-interface FSI methodology. Contours: Q-criterion. Contact between rigid and elastic bodies via a new IIM-based sharp-interface FSI methodology. Colors: flow speed (red=fast, blue=slow). APPLICATION | poster |
TORCH Digitization Hub: Streamlining Digitization Workflows for Natural History Collections Mr. Jason Best1, Mr. Diego Barroso1, Dr. Brian Witte2 1Botanical Research Institute Of Texas, Fort Worth, United States, 2Software Developer, , United States The TORCH Digitization Hub is a web-based platform designed to support specimen digitization workflows for multiple participants of a larger digitization group as well as workflows of individual organizations. The Hub bridges the gap between initial image capture and dissemination of images and metadata through specimen data portals. It is designed to provide collection managers, data managers, and digitization technicians with tools to simplify the processes of image upload, quality control, data extraction, and derivative image generation. The hub is a platform built on a foundation of open source components, allowing it to be freely distributed and modified and helping to accelerate the digitization workflows of natural history collections. Although many natural history collections have existing digitization workflows, these may not scale well internally or when multiple institutions must collaboratively digitize specimens across multiple collections. The Hub addresses some of these challenges by providing a solution for participants to upload specimen images into a central workflow platform where images and specimen data undergo multiple steps to ensure image quality, conformity, and completeness. Then, derivative images for dissemination are generated, and the complete end-product is uploaded to a web hosting platform to be used by the specimen portals. The Hub provides a web-based interface for managing workflows, monitoring progress and performance, and generating reports. It can be hosted in the cloud to support distributed digitization projects, or hosted locally to support workflows within a single institution. While the Hub was designed for the herbarium digitization workflows of the Texas Oklahoma Regional Consortium of Herbaria (TORCH) Thematic Collections Network, it can be adapted for other types of collections and workflows and, due to being open source, can be extended with other image management tools and technologies such as OCR and computer vision. The TORCH Digitization Hub project code and documentation is available at https://github.com/TORCH-TCN/torch_hub. | poster |
OICR - MaRS Centre, West Tower 661 University Avenue, Suite 465 Toronto, Ontario, Canada http://oicr.on.ca/ EMBL-EBI Wellcome Trust Genome Campus Hinxton, Cambridgeshire, CB10 1SD, UK http://www.ebi.ac.uk NYU Langone Medical Center 550 1st Ave, New York, NY 10016, United States http://www.med.nyu.edu/ http://www.reactome.org Iden%fiers submission interface Pathway Analysis Tool Suite Fabregat A1, Weiser J2, Jupe S1, Garapati P1, Forner O1, Porras P1, Haw P2, D'Eustachio P3, Stein L2, Hermjakob H1 (1) European Bioinformatics Institute, Hinxton (UK) (2) Ontario Institute for Cancer Research, Toronto (Canada) What is Reactome? Reactome is a free, open-source, curated and peer-reviewed knowledgebase of biomolecular pathways. One of its goals is to provide intuitive bioinformatics tools for the visualization, interpretation and analysis of pathway knowledge to support basic research, genome analysis, modeling, systems biology and education. (3) NYU Langone Medical Center, New York (US) New Pathway Analysis The performance has been boosted by creating a data structure to model Reactome objects and relationships which is directly placed in memory. The data structure is composed of a radix tree (1) for the identifiers used as cross-references to the target entities, a graph (2) to model these entities and the relationships between them (like the species orthology) and double-linked trees (3) to model the hierarchy. What does the Tool Suite provide? The analysis tool suite contains an enrichment analysis, an expression data analysis and a species comparison tool. Results are presented in the Pathway Browser in tabular form within the details panel, as an overlay on pathway diagrams and hierarchy. Besides improving stability, performance, reliability and scalability to cope with future demands, we have also extended functionality. Reactome currently annotates 7,460 human proteins and 1,462 chemical compounds. The analysis tool provides an enrichment analysis for a dataset of 1,215 protein identifiers in ca. 2 seconds. The tool suite is available via a RESTFul service (http://www.reactome.org/AnalysisService/) so the different analysis can be easily integrated in third party software. 1 7 1 9 0 1 2 6 3 8 7 2 P 0 2 6 9 2 5 P10620 P10635 P10636 P11086 P60468 P60484 P05480 P10639 2 9 3 8 9 1 0 5 4 8 0 P05386 P12931 0 3 8 6 6 N E T 4 0 8 6 4 8 6 7 P12938 P12939 P11087 P10622 P29172 P60467 Mus Musculus RaDus Norvegicus Saccharomyces Cerevisae Bos Taurus Homo Sapiens Canis Familiaris Homo Sapiens Mus Musculus RaDus Norvegicus Saccharomyces Cerevisae Bos Taurus Canis Familiaris 1 2 3 1. RADIX TREE Space-optimized data structure to rapid lookup whether the target identifier is present in the Reactome data. When a identifier is found the result is a pointer(s) to the related graph node(s). 3. DOUBLE-LINKED TREE Represents the pathways and their parent-child relationships for each species in Reactome. Once the tree leaf is reached, the entity is flagged as found in each node from it to the root (unless it was flagged before). 2. ENTITIES GRAPH Represents orthology relationships between proteins of different species. Used for the projection option in order to speed up the analysis (no queries to the database are needed). ANALYSIS EXAMPLE Green arrows show use cases where the identifier is analysed in its own species. Red arrows show a use case where the identifier is projected to human during the analysis. Enrichment analysis results Expression data analysis results Contact Reactome Acknowledgements This work was supported by the US National Institutes of Health (P41 HG003751), Ontario Research Fund, the European Molecular Biology Laboratory Core Funding and the Centre for Therapeutic Target Validation (CTTV). Help Desk: help@reactome.org URL: http://www.reactome.org | poster |
Simplified 2D Cavity Model Flow Field Characteristics of the Simple 2D Cavity I. Introduction IV. Results • Atrial fibrillation (AFib) is the most common cardiac arrhythmia. • The risk of stroke is increased approximately 5-fold in patients with AFib. • In 91% of patients, atrial thrombi develop within the left atrium and appendage. • It is still not fully understood how the AFib-induced flow would change the hemodynamic conditions in the LA • In this study, we performed an in vitro tomographic Particle Image Velocimetry study to quantitatively characterize the pulsatile flow in the left atrium under regular (double peak) and simulated AFib (loss of A wave) waveforms. V. Conclusions CAD Model of Left Atrium • A 2D side-wall cavity model (depth-to-width ratio is 1.5) was used to examine the vortex dynamics under normal and AFib waveforms. Left atrial flow waveforms: simulated vs clinical data 3D Flow Streamlines for Normal Double-Peak LA Flow The Cardiovascular Flow Simulator Tomographic Particle Image Velocimetry (Tomo-PIV) II. Methodology Fluid Dynamics of the Human Left Atrium under Simulated Normal and Atrial Fibrillation Conditions: A in vitro Tomographic PIV Study Sifat K. Chowdhury, Al Habib Ullah, Zachary Posch, Yan Zhang* Department of Mechanical Engineering, North Dakota State University *Speaker; Corresponding Author: yan.zhang.4@ndsu.edu, +1(701)-231-9217 • Phase-locked planar and Tomographic Particle Image Velocimetry (PIV) were used to quantify the flow characteristics in a 2D cavity model and in a realistic LAA model, respectively • The PIV system consists of o Double-pulsed Nd:YAG lasers o Synchronizing timing unit o Four CCD cameras o Imaging processing software • A closed-loop cardiovascular flow simulator was constructed with a pulsatile flow generator to mimic the heart, under both normal and AFib waveforms, III. Test Model and Conditions 3D Left Atrium Silicone Phantom Pulmonary Veins Left Ventricle Chamber (simplified outlet) Appen dage • The refractive index (RI) matching: RI = 1.43 of the silicone model. Mixture of water-glycerin (40 % and 60 % respectively by volume) Regular and AFib Flow Waveforms • A lump-parameter numerical model was used • The regular LA flow boundary condition features a double-peak flow (E-wave and A-wave), representing the early LV suction and the late atrial pumping effects • The simulated AFib flow was generated by smoothing out the A-wave (2nd peak). • Flow rate: 5 Liters/min • Heart rate: 75 beats per minutes Velocity vectors and out-of-plane vorticity fields of pulsatile flow past the simple cavity (a) the normal LA mitral flow and AFib flow waveforms used for experiments; (b - e) the flow fields under normal double-peak LA waveform reveals higher momentum of vortical flow inside cavity throughout the cycle; (f - i) the flow fields under AFib waveform reveals the cavity vortical flow dissipates faster after the E-wave. VI. Acknowledgement We would like to acknowledge the American Heart Association for the funding support under the AHA Institutional Research Enhancement Award (AIREA) #19AIREA34470008. • The Simple Cavity experiment results indicate that compared with the AFib waveform, the “double-peak” of the normal LA flow helps maintain the momentum of vortical flow and reduce flow stasis inside the appendage cavity. • Tomographic PIV results of LA flow suggest: • The clock-wise rotating helical flow (posterior view) is a predominant feature for LA flow, regardless of normal or AFib conditions • The secondary peak of flow under normal condition feeds into the momentum/energy of the helical flow in the LA chamber, potentially reducing flow stasis compared to Afib • The results emphasize the important role of normal atrial pulsation. Cross-Section for Tomographic PIV Measurement Volume (Volume Thickness ~10mm) Left Right Anterior Wall Posterior Wall 3D Flow Streamlines for AFib Single-Peak LA Flow Velocity Magnitude (m/s) Specific Kinetic Energy (𝒎𝟐/𝒔𝟐) Veloc | poster |
@ F A C EITArcti c @ F A C EITArcti c @ fa c e _i t_arc tic @ The F A C E -IT Pro j e ct www.face-it-project.eu FACE-IT has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 869154. Five categories were defined, each containing two or three drivers of change: • Cryosphere: Sea-ice, Glacier mass balance, Terrestrial runoff • Physics: Seawater temperature, Salinity, Light • Chemistry: Carbonate system, Nutrients • Biology: Primary production, Biomass, Species richness • Social: Governance, Tourism, Fisheries Each of these drivers of change are themselves an important facet of the overall socio-ecological fjord system, and most drivers have multiple, often complex interactions with others. Some of which, such as light penetration into fjord waters, are both very important to understand, and yet very difficult to project into the future. Arctic fjords serve as a point of confluence between land and sea. They are also the point at which the highest levels of human habitation and natural productivity intersect. The Arctic is however changing extremely rapidly, requiring that the monitoring and reporting of these changes keep pace. But what exactly is it that is changing? Or more complexly, which changes are affecting what? To answer these questions a broad team of experts was assembled under the FACE-IT consortium to investigate the drivers of change to socio-ecological systems in Arctic fjords. A survey was conducted amongst the experts within FACE-IT on what types of data (social and natural) were most important when studying change in Arctic fjords. This process created a long list of potentially important drivers (QR right), which were used to guide the review of available literature in the space. Finding the drivers of change We are providing a framework for future studies on any of the facets of change within Arctic fjord socio-ecological systems. The review publication (QR right) provides the necessary literature background to explain and prioritise the importance of the many drivers of change. The connected dataset provides researchers with the necessary data foundation to begin studying the historic state of the primary drivers presented here. After multiple rounds of deliberation the key drivers of change were refined down to a manageable length, and all in situ sampled data available for these drivers were sourced and amalgamated. This dataset was published open access and may also be queried via a user interface constructed by FACE-IT (QR right). Fig. 1 The interconnections between different drivers of change for socio-ecological Arctic fjord processes according to the available literature. The centre colour of the dots show the category of the drivers, and the border colour shows the direction of the long-term change. Arrows between dots show the direction of the relationship, and the colour shows if these are driving increases or decreases (or uncertain). Arctic fjord socio-ecological systems: Drivers of change Robert Schlegel1& all authorsofSchlegel et al. 2023 1Sorbonne University, CNRS, Laboratoire d’Océanographie de Villefranche, Villefranche-sur-mer, France robert.schlegel@imev-mer.fr Making all data available Which changes are affecting what?Cryosphere Physics Chemistry Biology Social Get Schlegel et al. 2023 | poster |
Combining NMR docking data with EPR distances and in silico calculations for a more complete model of colicin protein-protein interactions Morgan Bye, A. Stratford, C. Teutloff, G. Moore, F. MacMillan Henry Wellcome Unit for Biological EPR, University of East Anglia, Norwich, UK. School of Chemistry, University of East Anglia, Norwich, UK. (Currently) Fachbereich Physik, Freie Universitat Berlin, Berlin, Germany morgan.bye@uea.ac.uk morganbye.net Work supported by [1] Ferentz et al, Rev Biophys, 33, 29 (2000) [2] Palma et al, Proteins, 39, 372 (2000) [3] de Vries et al, Proteins, 69, 726 (2007) [4] MMM – http://www.epr.ethz.ch/software [5] HADDOCK – http://www.nmr.chem.uu.nl/haddock [6] Cascales et al, MMBR, 71, 1 (2007) Currently atomic resolution structures of protein-protein interactions are commonly limited to X-ray crystallography or NMR, developments in these fields have allowed for more accurate and biologically relevant structures to be developed [1] however ab initio information still remains a developing field [2,3]. Site-directed spin labelling (SDSL) in combination with electron paramagnetic resonance (EPR) pulsed electron double resonance (PELDOR) allows for the precise measurement of intra and intermolecular distances. New in silico methods allow for comparison to the experimental [4]. SDSL at several sites within a complex allows a three dimensional model to be built up using distance constraints, which when combined with NMR docking data gives a comprehensive model [5]. Using the well-characterised system, of colicin E9 and its cognate inhibitor, Im9 [6] a comprehensive solution is being developed to combine such NMR docking models, with PELDOR distance (and angle) constraints and in silico computations which are comparable to X-ray crystallographic models. The biology During times of stress it is evolutionarily beneficial to have an advantage over the competition, resulting in E. coli having developed colicins which act as bactericides to other species [1]. Here we focus upon the DNase colicin E9. To provide immunity to the host it is co- expressed with an immunity protein, Im9. A simple diagram of the E9 action. The E9 DNase domain (C domain) is in red, whilst the E9 T and R domains are in blue, Im9 in green Spin labelling Initial spin labelling efficiencies were < 1% using standard procedures. A change to buffer, aerobic conditions and the addition of EDTA, acceptable labelling efficiencies were obtained. E9 S3C 56% E9 S30C 25% E9 S80C 27% Im9 C23 33% X-band cw-EPR Here it can be seen (by lineshape, width and position of peaks) that the binding of the cognate protein slightly influences the cw spectra. All experiments here were run with the same parameters, with the same protein concentrations. References X – band PELDOR (above) Colicin E9 DNase domain in grey with residues S3C, S30C and S80C MTSL spin labelled. Colicin Immunity Protein, Im9, in cyan with residue C23 MTSL spin labelled (left) E9 S80C position showing all 95 spin label rotamers at 298K, electron location shown as a purple sphere. Rotamer opacity and sphere volume is proportional to rotamer population (above) E9 S30C PELDOR trace prediction at various temperatures, highlighted is the 80K prediction for comparison to below. E9 S30C cw spectra comparison at 80K (top) and 298K (bottom). In blue E9S30C*, green E9S30C*- Im9 red E9S30C*-Im9* cyan E9S30C-Im9* magenta Im9*. Where * indicates a spin label. 298K 80K Complete the PELDOR with other mutants Complete the data set at other frequencies Develop technique to accurately model Expanded to characterise other ill- defined non-cognate binding pairs of colicin E9 with Im2, Im7 and Im8. Pump Detect Field Swept Echo Fourier Transformation Distance Distribution Pulse Sequence PELDOR (using the 4 pulse technique shown left) has been conducted on the E9 S30C* - Im9 C23* complex at 50K. The result of this shows the main distance distribution to lie at 38.1 Å. This compares well with the 38.2 Å pre | poster |
Introducing extremely red quasars. Models predict that massive black holes mostly grow in obscurity inside a dusty starburst until a blowout of gas and dust quenches star formation and reveal a visibly luminous quasar. Dust-reddened quasars are believed to be in the transition phase and still partially embedded. At the peak epoch of galaxy formation and quasar activity, feedback should have the greatest impact. We discovered a remarkable population of “extremely red quasars” at z ~ 2–3 in the Baryon Oscillation Sky Survey (Hamann+17). ERQs have extremely red colors from rest-frame UV to mid-IR, high bolometric luminosities, and normal radio emission. They have exceptionally broad and blueshifted [OIII]5007 reaching speeds >6000 km s−1 (Perrotta+19). [OIII]5007 emissions in ERQs are compact. We obtained adaptive-optics integral-field spectra of 10 ERQs (Vayner+21; Lau+23). We identify physically distinct [OIII] kinematic components that are bimodal, and respectively trace ERQ-driven outflows and dynamically quiescent interstellar media. The outflows are ~1 kpc scales whereas the quiescent gas extends to few kpc. Compared to normal quasars the extremely fast ERQ-driven outflows are compact, supporting that ERQs are in a young evolution stage and represent unique physical conditions beyond orientation differences. The kinematically quiescent emissions are spatially- resolved but less extended than normal quasars, which can be explained by patchy obscuration. The hint of ionization cones suggests patchy torus. A deep survey for even redder, fainter ERQs. The extreme outflow properties are tied to their extreme red i−W3 (or z−W3) colors. We are searching for ERQs that are even redder to explore the possibility of more extreme physical properties tied perhaps to an even earlier evolution stage. We select candidates from DESI+WISE photometry based on the unique spectral energy distribution that is flat across rest-frame UV, and confirm with optical spectroscopy. If you study red quasars, I invite you to compare our selection techniques and the characteristic properties. Probing Quasar-Galaxy Evolution via Extremely Red Quasars / Probing Inflows onto Quasar Hosts via Associated Absorbers Marie Wingyee Lau (wingyeel@ucr.edu; University of California, Riverside), Fred Hamann 16000 16200 16400 16600 0 20 40 60 80 100 Average SB (10−17 cgs arcsec−2) 0.0" ≤ distance < 0.1" Data Fits 16000 16200 16400 16600 0 5 10 15 Average SB (10−17 cgs arcsec−2) 0.1" ≤ distance < 0.2" Data Fits 16000 16200 16400 16600 0 1 2 3 4 5 Average SB (10−17 cgs arcsec−2) 0.2" ≤ distance < 0.4" Data Fits 16000 16200 16400 16600 0.0 0.5 1.0 1.5 2.0 Average SB (10−17 cgs arcsec−2) 0.4" ≤ distance < 0.6" Data Fits Wavelength (Å) 16000 16200 16400 16600 0.0 0.5 1.0 1.5 2.0 Average SB (10−17 cgs arcsec−2) 0.6" ≤ distance < 1.0" Data Fits Wavelength (Å) Wavelength (Å) 16000 16200 16400 16600 0.0 0.5 1.0 1.5 2.0 Average SB (10−17 cgs arcsec−2) 1.0" ≤ distance < 1.4" Data Fits Wavelength (Å) Wavelength (Å) Wavelength (Å) −1 0 1 −1 0 1 (arcsec) (arcsec) 0.0 0.2 0.4 0.6 0.8 1.0 SB (10−14 cgs arcsec−2) J0006+1215 Hn3 Residual Relative Velocity (km s−1) Relative Velocity (km s−1) SiIV at z = 1.716 −400 −200 0 +200 +400 −2600 −2400 −2200 −2000 CIV 1548 CIV 1548 CIV 1550 CIV 1550 NV 1238 NV 1238 NV 1242 NV 1242 SiIV 1393 SiIV 1393 SiIV 1402 SiIV 1402 SiIII 1206 SiIII 1206 HI 1215 HI 1215 Left: Spectra extracted from nuclear and annular apertures of the reddest ERQ J0006+1215, and the best fits. We overplot the individual continuum, Hβ, broad and narrow [OIII] components. Right: Residual surface brightness map of J0006+1215 after subtracting the point spread function. The residuals are dominated by the narrow [OIII] component. Right: AB color vs. observed wavelength for candidates compared to median SED of known ERQs, Type 1 QSO with and without reddening, hot DOGs, highly reddened Type 1, Type 2 QSO, and starburst galaxy NGC 6240. Left: A newly-discovered ERQ. We see the characteristic s | poster |
Evolution of the HD 163296 Jet Axis Andrew Miller1, Aisling Murphy1, Christian Schneider2, Emma Whelan1, Catherine Dougados3, Jochen Eislöffel4 1Department of Experimental Physics, Maynooth University 2Hamburger Sternwarte, University of Hamburg 3IPAG, University of Grenoble 4Thüringer Landessternwarte Tautenburg, Tautenburg, Germany Abstract HD 163296 is a Herbig Ae star which drives a bipolar knotty jet with a total length of ~6000 au. Strong evidence exists that the disk of HD 163296 harbors planets which could affect the morphology of the jet, and ‘wiggling’ models have been proposed as a method to infer the presence of companions in other stars. Using the VLT/MUSE spectrograph, we investigate the morphology and proper motions of the HD 163296 jet with the aim of searching for evidence of its planetary system. In particular, we analyze the jet width and jet axis position with distance from the star and compare to ‘wiggling’ models to explore the possibility of orbital motion or precession in the jet axis. We conclude that there is no signature of this wiggle in the jet, and our results allow us to constrain the parameters of possible companions and further assess the robustness of the wiggling jet model as a method for detecting companions. 1. Introduction ●Astrophyiscal jets are ubiquitous in young stellar objects (YSOs), and accretion/outflow connection impacts circumstellar disk and potentially planet formation (Frank et al., 2014). ●Jets display complex structures, and sometimes present ‘wiggles’ in jet trajectory: potential signature of binary companions close to jet source (Masciadri & Raga., 2002; Murphy et al., 2021). ●Strong evidence for multiple planets embedded in HD 163296 disk (Teague et al., 2018; Pinte et al., 2018), and potential periodicity of jet ejection events may suggest a close-in companion (Ellerbroek et al., 2014) ●Using MUSE observations taken in 2018, we examine jet axis of HD 163296 to seek signatures of orbital motion or jet precession, and test the applicability of jet wiggling models to the case of planetary companions. 6. References 4. Results 3. Data Analysis ●Integrated spectro-images of forbidden emission lines (FELs) extracted from MUSE data cubes, focused on primarily on Hα, [N II]λ6583, and [S II]λλ6716,6731 (See Figure 1). ●Gaussian fitting along outflow axis yields jet FWHM and axis centroid position as a function of distance from the star. Deviation of centroids from axis center are examined for ‘wiggling’ signature. ●If wiggling motion is due to precession in jet axis, the motion can be expressed in terms of jet velocity (vj), precession period (ν), and half-opening angle (β) by: ●If wiggling is due to orbital motion of the jet source, the motion can be expressed in terms of orbital velocity (vo), jet velocity, orbital radius (ro), and phase angle () by: ●Each model is first fit with only vj constrained, then fit using proposed planets as function parameters. Figure 5: Parameter space of possible companion ranges expected to produce an observable ‘wiggle’ in the jet axis. Gray hatches indicated regions excluded by the MUSE observations. The green on the left indicates companions with unde- tectable effects. The top blue and bottom teal indicate periods too long or short to be observed. Figure 3: A plot of the [S II] centroids with free-fitted orbital and precession components over-laid. The distances are deprojected from the plane of the sky with x’ = xt / cos i. Only the jet velocity is held constant. The fitted parameters suggest a 0.2 M☉ companion at 8 au for an orbital motion model, while a precession model suggests a 48 MJup companion at < 0.35 au. The largest proposed planet in the HD 163296 disk is 2 Mjup, and the closest planet is located at approximately 83 au. These observations were collected with MUSE at the Very Large Telescope on Cerro Paranal (Chile), operated by the European Southern Observatory (ESO), under Program ID 099.C-0214(A). Figure 2: Co-added centroid (to | poster |
2018 LESSON PLAN Neelam Bharti Senior Librarian, Chemistry Matt Marsteller Principal Librarian, Engineering & Science Mike Melville Data Science Research Associate, Eberly Center Huajin Wang Librarian, Biology and Computer Science Sarah Young Senior Librarian, Public Policy Melanie Gainey Librarian, Biological Sciences University Libraries The Design and Implementation of Integrated and Interdisciplinary Information Literacy Instruction Project Design In 2017, we were invited to teach a one week unit on information literacy in large (180-250 students) MCS classes, EUREKA! and PROPEL. In 2018, we introduced a pre- and post-learning assessment. Our research question is how much do first-year science students learn from a one-week unit on information literacy? Lessons Learned Project Evaluation We compared students’ knowledge of information literacy concepts before and after a week of instruction in EUREKA! in the fall of 2018. We thank Ken Hovis for the opportunity to teach in the EUREKA! and PROPEL courses and for conversations about lesson planning. Insert Presenter’s picture here LECTURE • 1 hour lecture with 5 interactive Direct Poll questions and 2 think- pair-share exercises RECITATION • “Along the Graphene Trail” is a 7- step digital scavenger hunt that gives students the opportunity to navigate through several science information resources. • Recitations were led by teaching faculty. We supplied a lesson plan that included notes on strategy and pain points for each step of the exercise. • This exercise is easily adaptable for other disciplines We are developing interdisciplinary active learning lesson plans to teach information literacy in two large required science classes, EUREKA! and PROPEL. Our goal is to use learning gain assessments to systematically assess the effectiveness of different active learning exercises and target areas of weakness with interventions. INFO SCAVENGER HUNT at a glance • The learning gains assessment was administered on Canvas. • We used counter-balanced design to control for differences in the difficulty of the pre- and post-assessments and order effects. • Students were assigned version A or B depending on their recitation section and took one version at the beginning of lecture and the other at the end of recitation. • Students were given immediate feedback on the answers. • Results showed no significant difference between version A and B. THE SCENARIO You are browsing the June 2018 issue of Scientific American online and an article catches your eye “Quirky Graphene” by Prachi Patel. EXAMPLE STEPS STEP 1: As you read over the short news article, part of the article discusses electronic ID tags. Use the clues given in the article to locate the original work that they are describing. STEP 2: You have found the original article in ACS Nano. What clues do you have that this is a scholarly article? • Student engagement is quite variable across active learning exercises and recitation sections. • In spite of uneven engagement, 74% of students in 2017 reported in an attitudes post-assessment that they found a role-playing exercise to be useful for learning information literacy concepts. • Active learning exercises had to be fairly structured to be successful in these large classes. • Our implementation of Think-Pair-Share needs to be optimized. Students used the time to chat. • Group exercises worked better if the groups were limited to a few students. • The exercises often took a bit longer than the time we budgeted for them. • In 2018, we gained access to C@CMU and aimed to create lesson plans that built upon, rather than duplicated, that content. This allowed us to focus on more advanced concepts. • The learning assessment was really useful for understanding pre- existing knowledge and the effectiveness of our instruction and will guide lesson planning in future semesters. Students exhibited a significant learning gain from pre-test to post-test, t (181) = 10.71, p <.001, Cohen’s d = 1.04. Al | poster |
Restoring the West 2014 Comparing Channel Classification Frameworks to Better Inform Watershed Management Alan Kasprak1, Nate Hough-Snee1,2, Reid Camp1, Tim Beechie3, Gary Brierley4, Martha L. Jensen1, Joseph M. Wheaton1,2, Hiroo Imaki3, Gary O’Brien1 1 Utah State University, Department of Watershed Sciences, Logan UT 2 Utah State University, Ecology Center, Logan UT 3 NOAA Fisheries, Northwest Science Center, Seattle WA 4 University of Auckland, Auckland, New Zealand Introduction ▶The diversity of channel forms across a basin complicates watershed management Channel Classification: ▶Links watershed/local processes to channel form ▶Allows an understanding of watershed characteristics ▶May aid in prioritizing and planning stream restoration Study Setting: Middle Fork John Day River, Oregon ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! 0 10 20 30 40 Kilometers $ ! CHaMP Reaches Elevation (m) High: 2479 Low: 639 ! ! ! ! ! ! ! ! !! ! ! ! ! ! ! ! ! !! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! ! !!! ! Basin Characteristics ▶Located in northeastern Oregon, USA ▶117 km long, drains 2051 km2 ▶Physiographically-diverse meta-volcanic basin ▶Semi-arid watershed, large climatic and precipitation variability across elevations ▶Threatened native steelhead population ▶Ongoing intensive site-based fish and geomorphic monitoring, basin-wide channel classification efforts Methods: River Styles and Natural Channel Classification The River Styles Framework ▶Developed by Brierley and Fryirs [2005] ▶Hierarchical reach-scale classification using watershed- and local-scale variables ▶Number of River Styles is basin-dependent Natural Channel Classification ▶Developed by Beechie and Imaki [2014] ▶Predicts pre-disturbance planform ▶Streams < 8 m width using Montgomery and Buffington [1994] Straight Meandering Anabranching Braided Channel Slope 2-Year Discharge Valley Confinement Basin Forest Cover Basin Geology Data Sources Used: Channels < 3 m Classified via Slope: Pool-Riffle S < 0.02 Plane Bed 0.02 < S < 0.03 Step-Pool 0.03 < S < 0.08 Cascade S > 0.08 Valley Setting >90% of channel abuts confining margin Presence/absence extent of floodplain Planform Instream Geomorphic Units low sinuosity (superimposed meandering outline) Bed Material Texture River Style riffles, runs, cascades, steps plunge pools bedrock, steps, riffles, cascades riffles, runs, plane bed, bars cobble, gravel, sand boulder, cobble, gravel cobble, gravel ocsl. boulder STEEP PERENNIAL HEADWATER (Forced Meander) (Plane Bed Canyon) STEP-CASCADE cascades 2ndry Channel steps, pools bedrock boulder cobble low sinuosity STEEP EPHEMERAL HILLSLOPE CONFINED VALLEY BEDROCK RIVER riffles, runs, point bars, rapids cutbanks, anabranch step-pool cascade boulder, cobble, gravel, sand sand, gravel, cobble, boulders Laterally Confined occasional floodplain pockets floodplain absent recurring floodplain straight, slightly sinuous Floodplain Geomorphic Units boulder berms, terraces fine-grained floodplain, terrrace CONFINED VALLEY W/ FLOODPLAIN POCKETS ENTRENCHED BEDROCK CANYON fine-grained floodplain, terrrace Structural Elements* Valley Alignment CS woody debris CS and bar-forced woody debris BA woody debris CS and bar-forced woody debris BA woody debris CS = channel spanning BA = Bank Attached Methods: Natural Channel Design and Clustering Note: NCD and Clustering use data from the Columbia Habitat Monitoring Program (www.champmonitoring.org.) Natural Channel Design ▶Developed by Rosgen [1994] ▶Hierarchical reach-scale classification using local variables Statistical Clustering ▶Automated grouping with user-defined input data ▶Number of classes attempts to balance separating reaches with minimal reach overlap -50 0 50 100 -50 0 50 Middle Fork John Day Reaches by Cluster Membership PC 1 (86%) PC 2 (11%) Bankfull Width Profile Gradient D16 D50 D84 Wetted Width Width:Depth Ratio Cluster Membership 1 2 3 4 Predictor Variables Bankfull Width Sinuosity Gradient D16, D50, D84 Width-Depth Ratio Results: River Styles and Natur | poster |
www.postersession.com www.postersession.com Stars are thought to be commonly born and found in binary/ multiple systems. The diverse orbital configurations and rich dynamics in planet-bearing binary systems provide valuable conditions to test various theories and models of planet formation and evolution Conclusions We build our planet sample by retrieving data (on 04-March- 2021) from two online catalogues. i.e., (1) the catalog of exoplanet-hosting binaries with separations up to 500 AU[1], (2) the catalogue of exoplanets in binary star systems [2]. Furthermore, in order to have a unified criteria to define our sample, we adopted an upper mass limit (20 mJ) for planetary objects and a lower mass limit (50 mJ) for stellar objects. Finally, we obtain 110 planets in 80 systems, 61 (19) of which are single (multiple) planet systems. Introduction *To whom corresponding maybe addressed. Email: jwxie@nju.edu.cn Demographics of Exoplanets in Binaries (DEB). I. Architecture of S-Type Planetary Systems Revealed by the RV Sample Xiang-Ning Su1,2，Ji-Wei Xie1,2*，Ji-Lin Zhou1,2，Philippe Thebault3 1 School of Astronomy and Space Science, Nanjing University, Nanjing 210023, People’s Republic of China 2 Key Laboratory of Modern Astronomy and Astrophysics, Ministry of Education, Nanjing 210023, People’s Republic of China 3 LESIA, Observatoire de Paris, Meudon Principal Cedex, France orbital configurations of planets in binaries Most planets in binaries are currently found in S-type, there are 211confirmed S-type planets. Among them, 116 are from radial velocity (RV) surveys, 89 from transit surveys and 6 from others. S-type: planets orbit one of the binary stars; P-type: planets orbit both the binary stars. sample heterogeneity and observational bias The sample heterogeneity and observational bias are obstacles toward a clear figure of exoplanet demographics in the binary environment. We only focus on S-type planet systems from RV surveys to reduce the sample complexity and thus better take into potential observational bias. Sample and Method Results quantifying the RV detection constraints We adopt RV signal injection-recovery test to quantify observational bias: • we collect the RV data of each system and extract the RV residual. • we inject a test RV signale, and generate a set of simulated RV data • we evaluate whether the injected planet signal can be recovered from the simulated RV data. single planets VS. multiple planets Multiple-planet systems are more prevalent in wide binaries whereas single-planet ones are, on average, found in tighter binaries. There are no difference between single and multiple planet systems in the statistics of planetary mass and eccentricity distributions after considering the effect of detection limit. But singles and multiples seem to differ significantly in the 2-D distribution of the period-mass diagram. There is a rectangular- shaped gap (period = 10-300 days and Msini = 160-640 )in the period-mass diagram of single-planet systems but not for multiples. Close VS. Wide Binaries The period-mass gap identified for single-planet systems is also preferentially found in close-binaries. There is a rising upper envelope planets in the period-mass diagram for wide binaries (and single star systems) which is not found in the close-binary subsample. 1. Single (multiple) planetary systems are mostly found in close (wide) binaries with separation aB< (>) 100- 300 AU. 2. In binaries, single and multiple-planet systems are similar in 1-D distributions of mass and period as well as eccentricity (in contrast to the "eccentricity dichotomy" found in single-star systems) but different in the 2-D period-mass diagram. Specifically, there is a rectangular-shaped gap in the period-mass diagram of single-planet systems but not for multiples. This gap also depends on binary separation and is more prominent in close binaries. 3. There is a rising upper envelope in the period-mass diagram for planets in wide binaries as well as in | poster |
Ontology Explorer: An Ontology-Based Visual Analytics System for Exploring Time Series Data in Oil and Gas Well-founded ontologies are a powerful tool to make apparent the seman- tics of the data that supports the decision-making process in surveillance en- vironments. Optimizing oil and gas production requires the right-time analysis of a large amount of data produced by several distinct data providers that adopt their conventions and formats. The main contributions of this work are: ▪Ontology Explorer, a new Visual Analytics system that leverages the con- cept of Ontologies in the interactive exploration of time series in digital twins. ▪A case study that demonstrates an application of the Ontology Explorer in the oil and gas digital twins. SUMMARY ONTOLOGY EXPLORER SELECTED REFERENCES ACKNOWLEDGMENT REQUIREMENTS & ARCHITECTURE CONCLUSIONS AND FUTURE WORK • This work presents the Ontology Explorer, a visual analytics system for time series data in the oil and gas field, enhanced by the O3PO ontology to enable semantic interactive exploration of data. • Leveraging the semantics of the domain, the tool allows users to filter data in terms that closely reflect the core business, relieving the extra burden of thinking about the way information is stored. • Future work will focus on the ontological treatment of processes related to petroleum production (e.g., the event of injection loss), aiming to pro- vide a similar semantic exploration of them. We plan to release a general version of the tool, allowing users to plug in their ontologies, provided they meet certain requirements, along with necessary documentation. Also, regarding the larger landscape of the PeTwin project (petwin.org), the prototype has been validated and is being installed for evaluation and improvement at the corporate partner while also being integrated with a data analytics & machine learning module. 1. Nicolau Santos, Jonathan Rivera, Rafael Petry, Fabrício Rodrigues, Givanildo Nascimento, João Comba, Mara Abel. Ontology Explorer : An Ontology-Based Visual Analytics System for Exploring Time Series Data in Oil and Gas. Formal Ontology in Information Systems: Proceedings of the Fourteenth International Con- ference (FOIS 2023). IOS Press, 2023. 2. Nicolau O. Santos, Mara Abel, Fabrício Henrique Rodrigues, and Daniela Schmidt. Towards an ontology of offshore petroleum production equipment. In Emilio M. Sanfilippo, Mohamed-Hedi Karray, Dimitrios Kyritsis, and Arkopaul Sarkar, editors, Proceedings of the 12th International Workshop on Formal Ontologies meet Industry (FOMI 2022) Co-located with workshops about the Industrial Ontology Foundry (IOF) and the European project OntoCommons (EU H2020 proj- ect), Tarbes, France, September 12-15, 2022, volume 3240 of CEUR Workshop Proceedings. CEUR-WS.org, 2022. 3. Nicolau Santos, Fabrício Rodrigues, Daniela Schmidt, Régis Romeu, Givanildo Nascimento and Mara Abel. O3PO: A Domain Ontology for Offshore Petroleum Production Plants. Available at SSRN: https://ssrn.com/abstract=4280151 or http://dx.doi.org/10.2139/ssrn.4280151. Nicolau O. Santos, Jonathan C. Rivera, Rafael H. Petry, Fabrício H. Rodrigues, Givanildo S. Nascimento, João Comba, Mara Abel Lorem ipsum R1. Display the time series associated with sensor data as line graphs, supporting individual plots, or composed plots that allow comparisons; R2. Allow the user to define temporal filters to narrow the analysis to specific peri- ods (months, days, and hours); R3. Display the taxonomy of the ontology, allowing the user to hide, expand and inspect certain paths from the root of the taxonomy; R4. Support a text query from the user that highlights in the taxonomy the class nodes that match the input query, summarizing at each node the count of chil- dren nodes returned by the query; R5. Support selection of class nodes and inspection of their instances; R6. Support navigation through semantically non-hierarchical associations such as components or properties; R7. Support select | poster |
Lorraine Johnson JD|MBA*, Mira Shapiro MSc** *Principal Investigator, MyLymeData; **Biostatistician, Analytic Designers LLC Delayed Diagnosis Linked to Persistent Lyme Disease NAM Diagnostic Errors Schematic and Lyme Diagnostic Errors in Early Lyme Disease Most Patient Symptoms are Not Counted by CDC CDC Does Not Count Most Symptoms Acknowledgements We thank Dr. Elizabeth Maloney for her insightful comments, Allison Childs for graphic design, and the patients participating in MyLymeData, without whom this research could not have been done. Suggested Citation: Johnson, L.; Shapiro, M. (2019): Delayed Diagnosis Linked to Persistent Lyme Disease. figshare. Poster. https://doi.org/10.6084/m9.figshare.9947105 Contact lbjohnson@lymedisease.org | mira.shapiro@analyticdesigners.com Conclusion Most patients with persistent Lyme disease are not diagnosed until six or more months after symptom onset. Early diagnosis and treatment of acute Lyme disease usually prevents the progression to persistent Lyme disease. Diagnostic barriers include: using inaccurate geographic risk maps, failing to consider the most common early manifestations of the disease, and over reliance on imperfect lab tests. Remedying these identified diagnostic errors may significantly improve patient outcomes by providing patients with early diagnosis and treatment, which is associated with higher treatment success. References Newman-Toker, D. et al. Diagnosis 2019 Jul 11. doi:10.1515/dx-2019-0019 Khanna, G. AHRQ Blog. 2019 May 6. https://www.ahrq.gov/news/blog/ahrqviews/ahrqs-road-ahead.html NAM. 2015. Improving Diagnosis in Medicine. doi:10.17226/21794. Lee-Lewandrowski, E. et al. American Journal of Clinical Pathology. 2019 Jul. doi:10.1093/ajcp/aqz030 CDC, Lyme Case Report. 2009. https://www.cdc.gov/lyme/resources/LymeDiseaseCaseReportForm.pdf Introduction Lyme disease is the most common vector-borne disease in the United States. Diagnostic errors are believed to be common. Errors stemming from delayed or inaccurate diagnosis are generally the number one cause of serious harms among medical errors. (Newman-Toker 2019) The Agency for Healthcare Research and Quality has made reduction of diagnostic errors one of its three strategic priorities. (Khanna 2019) The National Academy of Medicine (NAM) has developed a schematic to identify points in the medical care system where diagnostic errors occur. (NAM 2015) It defines diagnostic medical error as “the failure to (a) establish an accurate and timely explanation of the patient's health problem(s) or (b) communicate that explanation to the patient." NAM looks at errors that occur when the patient first encounters the healthcare system, when clinical history is taken, during physical exam, and when diagnostic testing is being conducted. They then look at the consequences and costs of the diagnostic errors. This study analyzes patient responses from the MyLymeData Patient Registry using the NAM schematic to identify points of diagnostic errors in persistent Lyme disease. Sample Determination Methods and Results Lyme Lab Test Positivity Rates in 2016 The MyLymeData patient registry, developed by LymeDisease.org, enables patient healthcare data to be pooled. Since its launch in November 2015, over 12,000 patients have enrolled. This study included 3,903 US residents clinically diagnosed with Lyme disease who completed the Phase I Survey, which ran from November 2015-2016. Most participants (79%) have late or persistent Lyme disease. Questions included time to diagnosis, early symptoms, inaccurate lab tests, and whether their diagnosis relied on perception of Lyme in their state. The NAM schematic applied to acute Lyme disease diagnosis illustrates sources of errors including: inaccurate geographic exclusions, failure to consider full symptom range, and over reliance on inaccurate diagnostic tests. Diagnostic delays occur when clinicians restrict their diagnosis using the five CDC surveillance criteria: rash, neuropathy, Bell’s | poster |
Poster template courtesy Faculty & Curriculum Support (FACS), Georgetown University School of Medicine Zevatars; the future of personalized cancer medicine Shaila Mudambi Ph.D; Anna Zdunek; Mary Pasquale B.S; Kamden Gray; Seray Er; Ceylan Metin; Paige Burkhardt, B.S; Saumya Kasliwal B.S; Russell Sillmon M.S; Stephen Byers Ph.D; Michael Pishvaian M.D; Ph.D Eric Glasgow Ph.D Department of Oncology, Lombardi Comprehensive Cancer Centre, Georgetown University, Washington D.C. Background Figure 1. Differential drug response in cryopreserved liver metastasis biopsy (primary pancreatic cancer): A (a,c,e): Images of implanted tumor (patient ID : 1-01302019-A) on Day 1 of either FOLFIRINOX (4.2mM Fluorouracil, 1mM folinic acid, 0.08mM irinotecan, 0.08mM oxaliplatin) or Gemcitabine (0.1mM) + abraxane (0.005mM) treatment. A(b,d,f): Images of tumors 3 days post treatment. (B) Percentage of fish that survived after drug treatment (C) Change in area of the tumor between Day 1 and Day 3 in each embryo in each group (D) Average change in area between treatment groups. Error bars represent standard deviation (E) Percentage of fish with metastasis after drug treatment. Recapitulating patient drug responses in the clinic using Zevatars Humanizing zebrafish embryos Hematopoietic chimeras and immune tolerance in cmyb+/- zebrafish embryos (Refer to oral presentation 104) Zevatars determine patient tumor drug response Conclusions and Future directions Figure 2- Summary of patient drug responses; change in tumor size, fish with metastasis and fish survival after 3-5 days of drug treatment: (A-C) Primary PDAC biopsies from 6 patients treated with 2 doses of gemcitabine (D-F) Liver metastasis from 7 patients with either primary pancreatic or colorectal cancer treated with gemcitabine, abraxane or folfirinox. Bars represent maximum-minimum interval range with mean. Interestingly, response varies greatly from one patient biopsy to another, recapitulating patient tumor behavior observed in the clinic SSC-A FSC-A Blood from engrafted fish for flow cytometry to detect hematopoietic cell populations Table 1 : Cell lineages of engrafted RFP-expressing cells in 6 cmyb+/- transplanted fish Human blood cells persisted in injected fish for at least 15 days. Two larvae injected at 2dpf were dissociated after 12 days and Dye I positive blood cells were observed by flow cytometry Zevatars • Zevatars involve implanting fresh or cryopreserved patient tumor pieces from biopsy samples into zebrafish and screening for best drug response before treating patients in the clinic • The main advantage of using zevatars is rapid drug response screening and ability to assess tumor proliferation, angiogenesis, and metastasis by imaging and finally by implanting tumor pieces takes into account the tumor microenvironment as compared to current methods involving injecting dissociated tumor cells • In this study we describe the application of Zevatars for personalized medicine in pancreatic adenocarcinoma and colorectal cancer. Humanizing zebrafish • Currently we cannot use Zevatars to test immunotherapy so therefore we aimed to generate humanized fish • cmyb mutant fish fail to develop definitive hematopoietic cells and therefore provides us a way to completely replace fish system with a human hematopoietic system 2 1 • Zebrafish embryos exhibit immune tolerance when whole kidney marrow is transplanted prior to development of adaptive immune response • Human peripheral blood was collected and red blood cells (RBCs) were lysed and removed. RBC free blood was then labelled with DiI. • Stage of development is important for immune tolerance so DiI labelled blood was injected into circulation of wild type zebrafish embryos at different stages of development (2dpf-7dpf) • Human blood engrafted and fish survived at least until 14 days post injection when injected into 2dpf embryos • Zevatars can used to screen for the best treatment and hence applied to patients to improve personalized can | poster |
Inicio de vida sexual EDAD PORCENTAJE 12 años 1.7% 13 años 7.3 % 14 años 18.7 % 15 años 36% 16 años 19.3% 17 a 19 años 17% El embarazo en la adolescencia es un problema causado por multiples factores sociales. A pesar de la educacion en salud sexual y reproductiva, los embarazos adolescentes continúan siendo una preocupación en America Latina. Este estudio se enfoca en analizar factores subyacentes y mejorar los programas de prevención. INTRODUCCIÓN • Estudio en base a revisión bibliográfica de 11 artículos científicos en bases de datos como UpToDate, PubMed, Scielo, Elsevier, Journal y Google Scholar. • Términos de búsqueda solos o combinados con los operadores booleanos “AND” u “OR” de palabras clave embarazo adolescente, factores de riesgo, educación sexual y reproductiva, madres adolescentes y embarazos en Ecuador • Criterios de inclusión: idioma ingles-español, calidad de los artículos; criterios de exclusión investigaciones con más de 5 años de antigüedad. MATERIAL Y MÉTODO RESULTADOS • Estas adolescentes no tenían antecedentes de consumo de sustancias adictivas y su embarazo no era producto de una violación. El embarazo adolescente es un desafío importante en salud sexual y reproductiva, con implicaciones para el bienestar materno-infantil. Se requiere abordar los diversos factores que contribuyen al embarazo adolescente, con énfasis en la educación, la prevención y el acceso a servicios de salud adecuados. CONCLUSIÓN Guanoliquin Sonia, Pilatasig Erika, Tarco Estefanía edad porcentaje 14 a 19 años 62% 20 a 44 años 38% EDAD DE LA PAREJA DECISIÓN DE LA GESTANTE PORCENTAJE ABORTOS 55% CONTINUA LA GESTACION 45% Análisis de los Factores Subyacentes que Contribuyen a los Embarazos Adolescentes a Pesar de la Promoción y Educación en Salud Sexual y Reproductiva TOTAL CASO MUJERES 10-14 AÑOS 15-18 AÑOS 19-24 AÑOS 22239 7587 6053 8599 EMBARAZOS POR NO USO DE METODO ANTICONCEPTIVO 71,6% 58,0% 59,3% | poster |
Binaural Audio Tools for the Creative Industries MORE INFORMATION www.binci.eu @BINCI_EU NEW CULTURAL EXPERIENCES THROUGH 3D AUDIO www.binci.eu The project has received funding from the EU’s Horizon 2020 programme. Grant Nº 732130. 3D AUDIO IN MUSEUMS & CULTURAL SITES ewesemann@antennainternational.com PROJECT COORDINATOR info@binci.eu All partners of the BINCI project have been working collaboratively to develop an integrated market-ready software and hardware solution to ease the production, postproduction and distribution of binaural or 3D audio content. Sound designers, producers and artists will be able to create 3D audio content for interactive applications in the fields of music, virtual reality and cinema more easily. BINCI is a EU-funded project aimed at providing audio technology solutions to the European Creative Industries in order to push and pull the European market offer of innovative audio contents. THE PROJECT | poster |
NANOAOD: a new compact event data format in CMS Karl Ehatäht (NICPB, Tallinn) on behalf of the CMS collaboration karl.ehataht@cern.ch Future prospects References • Promote the format to achieve target adoption of 50-70% of all CMS physics analyses • Develop customized NANOAOD formats for specialized tasks such as automation of object calibration workflow • Explore the possibility to add support for alternate choices of generator information and parton distribution functions which are currently expressed as event weights but do not fit within the typical NANOAOD event size • Increase the frequency of producing new NANOAOD Ntuples [1] "The NanoAOD event data format in CMS", M. Peruzzi, G. Petrucciani, A. Rizzi, ACAT 2019 [2] "A further reduction in CMS event data for analysis: the NANOAOD format", M. Peruzzi, G. Petrucciani, A. Rizzi, EPJ Web Conf. Volume 214, 2019 AK4 jets, 382, 23% Generator-level particles, 310, 19% Electrons, 117, 7% Generator-level AK4 jets, 91, 6% Vertices, 87, 5% Hadronic taus, 84, 5% Muons, 75, 5% Trigger objects, 73, 4% Others, 422, 26% 1-3 MB 500 kb 50 kb 1-2 kb RAW AOD MINIAOD NANOAOD Event size Introduced in year 2009 / 2010 Run1 2011 / 2012 LS1 2013 / 2014 End of Run2 2018 / 2019 Typically run twice a year ~1 month runtime, run every few months 1-2 week runtime Motivation ROOT Ntuple ‒ nObject ‒ Object_var[i] ‒ Object_otherIdxQualifier[i] ‒ ... Self-descriptive collection name (example: Electron, Muon, Tau, Jet) Size of the collection (range of [i]) (example: nMuon, nPhoton) Link / cross-reference to associated collection (example: Muon_jetIdx, GenPart_genPartIdxMother) Event-level variables such as: MET (MET_pt, MET_phi), PDF weights (n/LHEPdfWeight), trigger bits (HLT_*), … i-th object in the collection Attribute of the object (example: Tau_eta, Jet_btagDeepB) Provenance tracking TTree::GetEntry() to access the event content ROOT::TTree ROOT::TBranch Figure 2. Breakdown of a simulated 𝑡ҧ𝑡event by average storage size of its high level objects (in bytes). Figure 1. Evolution of data tiers used in CMS. Figure 4. Structure of NANOAOD Ntuple [2]. ‒ Events ‒ LuminosityBlocks ‒ Runs • Standardized access to complex high level physics objects – simplifies automation of physics analyses • No need for CMS software to perform data analysis • Lower barrier of entry for new students • Enables open data access for people outside CMS • Documentation of physics objects embedded in NANOAOD Ntuples • Increases integrity and quality of physics analyses • Modular structure of the NANOAOD format promotes parallel and continuous development • Time between data recording and publication shortened • No need for custom Ntuple production by individual analysis groups • Typical thresholds used in physics analyses applied to high level physics objects (𝜇, 𝑒/𝛾, 𝜏ℎ, jets) • Storing the output of 𝑒/𝛾, 𝜏ℎand 𝑏-jet identification algorithms, rather than the input variables to these algorithms • Not storing redundant information that can be later derived from the event content (such as systematic variations of jet energy scale) • Not storing 32-bit floating point numbers at full precision because experimental measurements are not performed at this high precision • File size further reduced with LZMA compression algorithm • Production fast at 10 events / second / core • Reading faster than kHz with decompression • Required storage in data tiers projected to reduce by a factor of two (more than 2 exabytes) if 50% of the analyses switch from MINIAOD to NANOAOD during HL-LHC [1] • No tracks or individual particle • No details about detector configuration candidates, store jets instead • No object cleaning and skimming applied to maintain flexibility on an analysis level 0 20 40 60 80 100 120 09/2017 03/2018 09/2018 03/2019 09/2019 Number of forks Centrally maintained companion tool available to perform analysis-specific steps after NANOAOD production: • Computation of systematic variations of physics observables, data to simulation c | poster |
TERAHERTZ COMMUNICATION: A STORY OF BANDWIDTH AND SILICON PHOTONIC INTEGRATION PHOTONICS RESEARCH GROUP & IDLAB, DEPARTMENT OF INFORMATION TECHNOLOGY (INTEC) Dennis Maes, Emilien Peytavit, Bart Kuyken, Sam Lemey Contact dennis.maes@ugent.be linkedin.com/in/dennis-maes/ Wireless networks are hungry for bandwidth The need for higher wireless data rates makes the radio spectrum congested. In addition to spatial multiplexing and spectral optimization, higher carrier frequencies with more available bandwidth can be used to accommodate this need. The mmWave and terahertz (THz) spectrum (100 GHz and beyond) offer this much needed bandwidth. (IEEE 802.15.3d- 2017) >50 Gbit/s - 300 GHz 69 GHz (1), 13 GHz(5) 5G NR (3GPP rel.15) sub-6 GHz mmWave THz 4G) (LTE) 300 Mbit/s - 800, 1800, 2600 MHz BE 20 MHz (10s) WiFi 5 (IEEE 802.11ac) 6.9 Gbit/s - 5 GHZ 160 MHz (2)EU WiFi 4 (IEEE 802.11n) 900 Mbit/s - 2.4, 5 GHz 40 MHz (2+12)EU WiGig (IEEE 802.11ad) 7 Gbit/s - 60 GHz 2 160 MHz (6) 4G+ (LTE-A) 1 Gbit/s - 800, 1800, 2600 MHz BE 100 (5x20) MHz (10s) WiFi 6E (IEEE 802.11ax) 9.6 Gbit/s - 2.4, 5, 6 GHz 160 MHz (0,3,3)EU Max. data rate - Carrier frequency Max. channel bandwidth (supported # of channels) > 10 Gbit/s - 0.7, 3.8, 26, 36 GHz BE 100 MHz (<10), 400 MHz (<10) Phased Antenna Array (PAA) Array of integrated opto-electronic antenna elements Low-loss optical Si3N4 waveguides Optical beam forming network (OBFN) On-chip modulatorIntegrated amplifiers Integrated laser sources Ultra fast photodetector Laser 2 Laser 1 Modulator νopt λ1 > λ2 Optical waveguides Electrical waveguide fRF fTHz fTHz THz signals can be efficiently generated by on-chip photomixing Beating two optical signals on a photodetector (photomixing) will result in a radio signal at their offset frequency. The only limitation is the conversion efficiency of the photodetector, a very high bandwidth photodiode is thus needed. Beamforming improves signal strength but requires a low-loss feed network A phased antenna array (PAA) is used to generate narrow, high-gain beams. Beamforming not only improves signal strength to overcome higher path loss at THz frequencies, but it also allows more spectral reuse. # of antenna elements Gain [dB] 1 2 5 10 20 50 100 200 500 20 17 13 10 7 3 0 -3 -7 -10 -13 -17 Optical power splitterPRF∽Popt2Feed network (CMOS) Feed network (III/V) Feed network (SiPh) Optical (SiPh full-passive)Distributed amplifier Optical (SiPh + III/V optical amplifiers) Electrical (CMOS)Power splitter Electrical (III/V)More antennas+10 dB/dec -10dB/dec -20dB/dec Array gain A Silicon Photonic (SiPh) beamforming chip leverages the low-loss waveguides for efficient RF signal routing and allows distributed optical amplification to overcome power splitting losses. A high-speed photodiode on a low-loss SiPh platform enables data rates beyond 100 Gbit/s at 280 GHz 16-QAM at 35 GBaud (140 Gbit/s) 11% EVM 32-QAM at 25 GBaud (125 Gbit/s) 7% EVM By means of micro transfer printing, we have heterogeneously integrated a Uni- Traveling-Carrier photodiode (UTC-PD) on a Silicon Nitride (SiN) waveguide. This ultra-fast photodetector has a bandwidth of 155 GHz. We demonstrated a back-to-back THz link at 280 GHz achieving data rates beyond 100 Gbit/s. Electrical contact pads to extract THz signal SiN optical grating coupler SiN low-loss waveguide Waveguide-coupled photodiode 100 µm 10 µm PD coupon just after transfer-printing Conclusion Immense bandwidths are available in the THz spectrum Photonic chips offer compact solutions for beamforming Heterogenous integration of UTC-PDs on SiN waveguides results in ultra-fast detectors needed for photomixing These detectors enable super-fast THz links at 280 GHz with a data rate of more than 100 Gbit/s More information? D. Maes et al., “High-Speed Photodiodes on Silicon Nitride with a Bandwidth beyond 100 GHz“, 2022 Conference on Lasers and Electro-Optics (CLEO), 2022 | poster |
Qualität von Montessori-Kindergärten und traditionellen Kindergärten und ihre Effekte auf die kindliche Entwicklung Antonia Baumeister, Heiner Rindermann, Technische Universität Chemnitz Kerstin Steinhauser, Karl-Franzens-Universität Graz Stichprobe Raum Graz: 8 Kindergärten; 3 Kindergruppen; 1 Kinderhaus Alter der Kinder: 4;2 – 7;3 Jahre (M = 5;10 J.; SD = 0;6 J.) Montessori-Kindergartenpädagogik „Hilf mir, es selbst zu tun“ nach Maria Montessori (1870 - 1952) Besuchsdauer: mind. 6 Monate – 4 Jahre (M = 2;5 Jahre; SD = 8 Monate) Aufenthaltsdauer pro Woche: mind 15 Std – max 46 Std ( ) Grundsatz: Förderung der Entwicklung, Selbständigkeit & Unabhängigkeit des Kindes, z.B.: Sinnesmaterialien Sprachförderung Mathematische Materialien Übungen des tägl. Lebens http://www.einsatzzylinder.de/ Ausrichtung Betreuungsstätte Anzahl Kinder weiblich männlich traditionell 7 52 27 25 Montessori 5 45 29 16 N 12 97 56 41 Aufenthaltsdauer pro Woche: mind. 15 Std. max. 46 Std. (M = 30 Std. 37 Min.; SD = 7 Std. 49 Min.) Ergebnisse Höhere Qualität von Montessori-Kindergärten (β = .68, p < .01; d = 1.36) Höhere Qualität des Kindergartens sagt höhere kognitive Fähigkeiten (β = .36, p < .01) und bessere hli h E t i kl h (β 37 01) Untersuchungsfragen Weisen Montessori-Kindergärten eine höhere Qualität auf als traditionelle Kindergärten? Hat die Qualität des Kindergartens einen Einfluss auf die kognitiven und sprachlichen Fähigkeiten sowie die sprachfreie Intelligenz? h sprachliche Entwicklung vorher (β = .37, p < .01); kein Zusammenhang mit sprachfreier Intelligenz (β = .20, p > .10) Höhere Bildung der Eltern sagt höhere kognitive Fähigkeiten (β = .49, p < .01), bessere sprachliche Entwicklung (β = .42, p < .01) sowie höhere sprachfreie Intelligenz (β = .36, p < .01) vorher - 3 - Hat die Bildung der Eltern einen Einfluss auf die kognitiven und sprachlichen Fähigkeiten sowie die sprachfreie Intelligenz? - 1 - Methode Variable Funktion Messung 3 Diskussion 1) Höhere Qualität von Montessori-Kindergärten durch: - mathematische, motorische & sprachliche Förderung - höhere Qualifikation der Kindergartenpädagoginnen (z.B. Zusatzausbildungen in: Mototherapie, Malspieltherapie, Interkultureller Pädagogik, Waldpädagogik, Variable Funktion Messung Inhaltliche Ausrichtung (traditionell vs. Montessori) Prädiktor Befragung Schul- & Berufsausbildung der Eltern Prädiktor Befragung Kindergartenqualität (Rahmenbedingungen 1.) Kriterium 2.) Prädiktor Kindergarten-Skala (KES-R; Tietze, g g , p g g , Suchtprävention im Kindesalter) - bessere Rahmenbedingungen (z. B. Größe des Innenraumes) - pädagogische Arbeit & Elternarbeit eventuell zielgerichteter als in traditionellen Kindergärten 2) Bildung der Eltern weiterhin sehr wichtig für Entwicklung der Kinder. (Rahmenbedingungen, Ausbildung, Elternarbeit, pädagogische Arbeit, Förderung sprachlicher / motorischer Entwicklung & mathematischer Kompetenzen) 2.) Prädiktor ( ; , Schuster, Grenner & Roßbach, 2007) (Skalenauswahl) Sprachliche Entwicklung Kriterium Wiener Entwicklungstest (WET; Kastner-Koller & Deimann 2002) Literatur Kastner-Koller, U. & Deimann, P. (2002). Wiener Entwicklungstest: Ein Verfahren zur Erfassung des allgemeinen Entwicklungsstandes bei Kindern von 3 bis 6 Jahren. 2. Aufl. Göttingen: Hogrefe. Schmidtke, A., Schaller, S., & Becker, P. (1980). CPM Raven-Matrizen-Test. Weinheim: Beltz. Tietze, W., Schuster, K.-M., Grenner, K. & Roßbach, H.-G. (2007). Kindergarten-Skala (KES-R) Feststellung und Unterstützung pädagogischer Gesamtwert kognitiver Fähigkeiten Deimann, 2002) (Skalenauswahl) Sprachfreie Intelligenz Kriterium Coloured Progressive Matrices (CPM; Raven & Raven Jr., 1976; Schmidtke, Schaller & 1 < Fakultät/Bereich/Professur > Kontakt: antonia.baumeister@psychologie.tu-chemnitz.de 47. Kongress der Deutschen Gesellschaft für Psychologie (DGPs), Bremen, 26.-30. September 2010 Kindergarten-Skala (KES-R). Feststellung und Unterstützung pädagogischer Qualität in Kindergärten. 3. Auflage. Berlin | poster |
Introduction There are over 7000 rare diseases and most of these do not have a treatment or a cure. The general public is barely aware that they exist unless a member of their family or a friend has the disease. We are already seeing pharmaceutical companies eyeing rare diseases as a potential money machine with some treatments costing >$300,000 per year/ per patient. We are increasingly seeing a shift to more companies, institutes and researchers openly sharing data on the internet. Alongside this there are increasing efforts by researchers to publish in open access journals and release data into open or free databases. Researchers working on these diseases are generally spread throughout the globe and in developing countries. Many of the rare diseases attract little funding and therefore less research, so how can we draw attention to them? How can we possibly connect all of this data and impact research? We believe scientific mobile apps [1] may have a role to play in collaboration and aggregating the available data for different diseases. This lead us to develop a free app called Open Drug Discovery Teams (ODDT) for the sharing of scientific data initially focused on neglected and rare disease drug discovery. These tools could also be used as part of a drug repurposing [2, 3] or other strategy for rare or orphan disease research [4]. We have created a user interface via the ODDT app, for iOS-based devices (iPhone, iPod and iPad) that is "Flipboard or magazine-like". The user initially selects from a list of topics, and from there can flip through recently posted content. The app was launched April 12 2012 and is free for anyone to use, and provides content-consumption features as its primary purpose. We are capturing content on a server and make use of Twitter as the primary source (as a proof of concept), which is regularly polled and assimilated into the data collection. The service provides an API for accessing ODDT topics and content. As the project evolves, the server will be gradually augmented to recognize particular data sources and information streams, and provide value added functionality. Currently it is able to recognize chemical data such as molecular structures, reactions and datasheets. The project is open to participation from anyone and provides the ability for users to make annotations and assertions, thereby contributing to the collective value of the data to the engaged community. Methods Using the hashtags #huntingtons, #sanfilipposyndrome and #hhf4gan we capture Twitter feeds for Huntingtons Disease, Sanfilippo syndrome and Giant Axonal Neuropathy, respectively. We can also inject chemistry related and other content into the App. Results Discussion In order to expand ODDT further we have launched an IndieGoGo crowdfunding campaign to fund support of the server for 3 years and increase the number of sources of data integrated (http://www.indiegogo.com/projects/122117). In return donors get to select additional diseases which we will add into the App. This will enable the community to decide which rare diseases can be followed in the same way as those currently (Fig 1). References [1] A. J. Williams, S. Ekins, A. M. Clark, J. J. Jack, R. L. Apodaca, Drug Disc Today 2011, 16, 928. [2] S. Ekins, A. J. Williams, M. D. Krasowski, J. S. Freundlich, Drug Disc Today 2011, 16, 298. [3] S. Ekins, A. J. Williams, Pharm Res 2011, 28, 1786. [4] C. L. Beaulieu, S. Ekins, M. Samuels, K. M. Boycott, A. MacKenzie, Orphanet J Rare Dis 2012, In Press. Acknowledgements We kindly acknowledge Jill Wood and Lori Sames for supplying the images for Sanfillipo Syndrome and GAN and we thank our alpha testers. Open Drug Discovery Teams: Sharing Data for Rare Diseases Sean Ekins1 and Alex M. Clark2 1 Collaborations in Chemistry, 5616 Hilltop Needmore Road, Fuquay Varina, NC 27526, U.S.A. 2 Molecular Materials Informatics, 1900 St. Jacques #302, Montreal, Quebec, Canada H3J 2S1. We have defined a small number of rare orphan disease | poster |
101 102 Eν [GeV] 0.0 0.2 0.4 0.6 0.8 1.0 P (νµ →νµ) cos(θ) = −1.00 (L = 12737 km) No sterile ∆m2 41 = 10 eV2 ∆m2 41 = 0.1 eV2 ∆m2 41 = 10−2 eV2 ∆m2 41 = 10−3 eV2 ∆m2 41 = 10−4 eV2 SK (2015): Phys. Rev. D 91, 052019 IC (2017): Phys. Rev. D 95, 112002 IC (2020): Phys. Rev. D 102, 052009 ANTARES (2019): J. HEP 2019, 113 MINOS+(2020): PRL 125, 071801 ORCA115: J. HEP 2021, 180 (2021) Sensitivity of KM3NeT/ORCA6 to light sterile neutrino mixing parameters Louis Bailly-Salinsa on behalf of the KM3NeT collaboration aUniversité de Caen Normandie, ENSICAEN, CNRS/IN2P3, LPC Caen UMR 6534, F-14000 Caen, France KM3NeT/ORCA Cherenkov neutrino telescope under construction in the Mediterranean sea. Atmospheric ν 1 - 100 GeV. Light Sterile Neutrino Analysis workflow ORCA6 510 days, 433 kton-year Expected number of events: Loss of sensitivity <10-2 eV2 1) Short BaseLine (SBL) anomaly: Δm2 41~ 1 eV2 MSW resonance > 1 TeV: hard to see with ORCA ORCA main feature on P(νµ→ νµ) at 1st osc. maximum (E~25 GeV for vertical upgoing νµ) θ24 & θ34 change amplitude; when both ≠0, change position depending on δ24 value Sensitivity Results 2) Dependency on Δm2 41 Wide range of E & L: can scan wide Δm2 41 range including very-low sterile (Δm2 41 <10-2 eV2) mass, not yet constrained by cosmology. E~25 GeV feature disappears for very low-mass, instead effects at ≤ 10 GeV (L/E > 1000 km/GeV) 101 102 103 104 Eν [GeV] 0.0 0.2 0.4 0.6 0.8 1.0 P (νµ →νµ) cos(θ) = −1.00 (L = 12737 km) No sterile sin2 θ24 = 0.1 sin2 θ34 = 0.1 sin2 θ24 = sin2 θ34 = 0.1 sin2 θ24=0.1 Determine parameters of interest x through Maximum Likelihood Estimator: (Poisson + Gaussian for constrained nuisance parameters η’) Std osc. params: NuFit 5.0 w/o SK + Daya Bay for Δm2 31 HONDA 2014 @ Fréjus, solar minimum GENIE 3 classes: low VS high-purity (LP / HP) tracks VS showers (BDT) Pν y→ν x(Et ,θt) σν x(Et) ϕatm ν y (Et,θt) Ri(Et,θt,ν x, Er ,θr) ni( Er,θr) × × × ⇒ ϕatm ν y (Et,θt) M eff ν x (Et) × νhor/νver skew νe/νe skew νµ/νµ skew νµ/νe skew Spectral index Overall norm. ντ-CC norm. NC norm. Energy scale HE light sim. HP track norm. Shower norm. Muon norm. Δm2 31 θ23 Systematics 1 Detection Unit (DU) = 18 DOMs 115 DUs when complete ⇒ 7 Mton instrumented water 3-D array of photomultiplier tubes: 1 Digital Optical Module (DOM) = 31 PMTs Constrained No prior Compare measured ni,j VS predicted µi,j 2D (Er, cos θr) reconstructed event distributions for each class i l (x , η)=2 ∑ i=1 N classes ∑ j =1 N bins [μi , j (x , η)−ni , j +ni , j ln( ni, j μi , j(x , η))]+∑ k=1 N priors ( ηk' −⟨ηk' ⟩ σk ) 2 ● Asimov data set in null hypothesis, both true mass ordering tested ● Assume Wilk’s theorem: Δl ∼χ2 2 ● No sensitivity to θ14 ⇒ θ14 = δ14 = 0 δ24 free unless stated otherwise HP tracks LP tracks Showers Total 1870 2002 1959 5831 Δm2 41- dependent sensitivities to θ24 and θ34 Sensitivity to Uµ4 and Uτ4 with Δm2 41 = 1 eV2 ORCA6 ≠ ORCA115 (21 Mt-y) ⇒ mostly from statistics ORCA6 not competitive for θ24 Close to SK and IC for θ34 Competitive for Uτ4 δ24 is important Δm2 41=1 eV2 Main goal: Neutrino Mass Ordering Here ORCA6 (6 DUs), operated Jan. 2020- Nov. 2021 References 10−3 10−2 10−1 100 sin2 θ24 10−4 10−3 10−2 10−1 100 101 ∆m2 41 [eV2] KM3NeT/ORCA6 Preliminary, 433 kt-y 99% CL sensitivity ORCA6 NO ORCA6 IO ORCA115 NO ORCA115 IO 99% CL upper limit SK (2015) IC (2020) MINOS+ (2020) 0.0 0.2 0.4 0.6 0.8 1.0 sin2 θ34 10−4 10−3 10−2 10−1 100 101 ∆m2 41 [eV2] KM3NeT/ORCA6 Preliminary, 433 kt-y 99% CL sensitivity ORCA6 NO, θ24 free ORCA6 IO, θ24 free ORCA6 NO, θ24 = 0 ORCA115 NO ORCA115 IO 99% CL upper limit IC (2017) SK (2015) 0.00 0.05 0.10 0.15 0.20 0.25 0.30 |Uµ4|2 = sin2 θ24 0.00 0.05 0.10 0.15 0.20 0.25 0.30 0.35 |Uτ4|2 = cos2 θ24 sin2 θ34 KM3NeT/ORCA6 Preliminary, 433 kt-y 99% CL sensitivity ORCA6 NO, δ24 free ORCA6 IO, δ24 free ORCA6 NO, δ24 = 0 ORCA115 NO ORCA115 IO 99% CL upper limit ANTARES (2019) IC (2017) SK (2015) | poster |
Kyung-Ae Park1,2 and Eun-Young Lee1 1 Department of Earth Science Education, Seoul National University, Seoul, Korea 2 Research Institute of Oceanography, Seoul National University, Seoul, Korea Abstract Study Area and Data Conclusion Comparison with Numerical Model Simulation Spatial Distribution of Extreme SSTs Extreme value analysis (EVA) has been extensively used to understand and predict long-term return extreme values. This study provides the first approach to EVA using satellite-observed sea surface temperature (SST) data over the past decades. Representative EVA methods were compared to select an appropriate method to derive SST extremes of the East/Japan Sea (EJS). As a result, the peaks-over- threshold (POT) method showed better performance than the other methods. The Optimum Interpolation Sea Surface Temperature (OISST) database was used to calculate the 100- year-return SST values in the EJS. The calculated SST extremes were 1.60–3.44 °C higher than the average value of the upper 5th-percentile satellite-observed SSTs over the past decades (1982–2018). The monthly distribution of the SST extremes was similar to the known seasonal variation of SSTs in the EJS, but enhanced extreme SSTs exceeding 2 °C appeared in early summer and late autumn. The calculated 100-year-return SSTs were compared with the simulation results of the Coupled Model Intercomparison Project 5 (CMIP5) climate model. As a result, the extreme SSTs were slightly smaller than the maximum SSTs of the model data with a negative bias of –0.36 °C. This study suggests that the POT method can improve our understanding of future oceanic warming based on statistical approaches using SSTs observed by satellites over the past decades. ◀Figure. (A) Shape parameter (k) and (B) modified scale parameter (σ*) with 95% confidence intervals for every value of the threshold (μ). The red dot indicates the 98th percentile of SSTs. Thresholds for POT • In this study, the 98th-percentile value was selected as the threshold by checking the change and significant interval of the shape (k) and scale (σ) parameters according to the threshold setting. • We selected the thresholds marked by red dots. These values have also been used in previous studies (Parey et al., 2007; Laurent and Parey, 2007; Cheng et al., 2014), which compute the extreme values of surface air temperatures. A similar approach was applied to calculate the extreme values of precipitation (Cheng and AghaKouchak, 2014). Monthly Distribution of Extreme SSTs ▲Figure. Examples for the computed result of the monthly extreme SST. (A-L) Distribution of the probability of monthly SST values, where the red line represents the fitted distribution for the computation of the extreme SST by the POT method and (M) Q-Q plot for all months. ▲ Figure. Spatial distribution of (A) monthly 100-year return SSTs using the POT method and (B) temperature differences between the computed SST extremes and mean values of satellite-observed SSTs (1982 – 2018) within the upper 5th percentile. ▲Figure. (A) Bathymetry of the Northwestern Pacific, where the red box shows the study area, and (B) spatial distribution of sea surface temperatures (SSTs) averaged for the period from 1982 to 2018 in the study area. Satellite-observed Sea Surface Temperature Data • The daily Optimal Interpolation SST (OISST) data • provided by the National Oceanic and Atmospheric Administration (NOAA)/Oceanic and Atmospheric Research (OAR)/Earth System Research Laboratory (ESRL) Physical Sciences Lab (PSL) • based on NOAA/AVHRR data the longest period from 1981 onwards • The data used in this study covered the period from 1982 to 2018. Simulated Sea Surface Temperature Data of Climate Model • The Coupled Model Intercomparison Project 5 (CMIP5) monthly data on single-level • extracted from global ocean data from Dec. 2005 to Nov. 2099 • obtained from the Representative Concentration Pathway (RCP) 4.5 experiment using the HadGEM2- ES model (UK Met Office, UK) St | poster |
Archaeological Subsurface Survey of Lighthouse Archaeological Subsurface Survey of Lighthouse Archaeological Subsurface Survey of Lighthouse P i t S th El th B h Point South Eleuthera Bahamas Point, South Eleuthera, Bahamas T cker Beckett Brigid Carr Charlie Fichtner Tucker Beckett, Brigid Carr, Charlie Fichtner, Rachael Pridmore, Sarah Sasek, and Daisy Spencer Rachael Pridmore, Sarah Sasek, and Daisy Spencer Advisors: Justin Symington Gabe Wofford Taylor Fargo and Francesca Perkins Advisors: Justin Symington, Gabe Wofford, Taylor Fargo, and Francesca Perkins Introduction Methods Introduction Methods An X and Y axis was created (see The Lucayans were a group of An X and Y axis was created (see figure 2) in order to establish waypoints people who migrated from Venezuela to figure 2) in order to establish waypoints where test pits would be dug for a sub- the Bahamas from the years of 2100 where test pits would be dug for a sub surface survey BCE to 500 CE. (see Figure 1) They surface survey. maintained residence there for about 1000 1000 years, until they came into contact i h C l b d hi i 1492 with Columbus and his men in 1492. Th i l ti k d t 40 000 di d Their population peaked at 40,000 died t ithi 20 Si th L out within 20 years. Since the Lucayans h d itt d th i littl Li hth had no written records, there is very little k b t th i lt Th h Lighthouse known about their culture. There has b h l i l k d i Lighthouse Bay g Road been some archaeological work done in th B h hi h h b f d Lighthouse Bay Road the Bahamas which has been focused i l i th i l d N mainly in the islands New P id S S l d d T k Providence, San Salvador, and Turks d C i t th i till h t and Caicos; yet, there is still much to learn. Th f thi t d t The purpose of this study was to t i th t f th P ascertain the nature of the Pre- C l bi t Li hth P i t Lighthouse Fi 2 Colombian usage at Lighthouse Point. Thi it h ff h d Lighthouse Figure 2 This site has offshore cays and ca es hich are closel associated ith Point caves, which are closely associated with Lucayan religious and ceremonial Steps to a Sub Surface Survey Lucayan religious and ceremonial traditions In addition there are reefs Steps to a Sub-Surface Survey traditions. In addition, there are reefs nearby to provide food and sandy nearby to provide food, and sandy beaches which would have made a good Excavate: beaches which would have made a good area to land canoes This information led Each test pit was a Soil Profile from Soil Profile from area to land canoes. This information led the archaeology team to hypothesize Artifacts by Areas Each test pit was a circle with a 50 Soil Profile from Li hth R d Soil Profile from the archaeology team to hypothesize that the Lucayans used Lighthouse Point 0 10 y circle with a 50 centimeter diameter Lighthouse Road Lighthouse Point that the Lucayans used Lighthouse Point for religious and ceremonial purposes 0-10 centimeter diameter and averaged 80 g for religious and ceremonial purposes. 10-20 a d a e aged 80 centimeters deep. 20-30 p Every 10 30-40 M y centimeters, dirt is 40 50 30 40 n C , removed from the 40-50 h in Lighthouse Road pit. 50-60 pth Lighthouse Road Li hth B p 60-70 Dep Lighthouse Bay 70-80 D Lighthouse Point Sift 80 90 70-80 Sift: 80-90 The dirt and 90-100 materials were 0 10 20 sifted through a 0 10 20 one quarter inch Number of Artifacts screen. Figure 3 Figure 4 Fi 5 Fi 6 Figure 3 Figure 4 Figure 5 Figure 6 Fi 1 Figure 1 Results Discussion Record: Results The majority of the materials found at Discussion We found no conclusive evidence of Lucayan Finally, our findings Literature Cited The majority of the materials found at Lighthouse Point were ecofacts and fire affected We found no conclusive evidence of Lucayan habitation or activity at Lighthouse Point However the y, g were recorded. Carr, Robert et Al. An Archaeological and Historical Assessment of Preacher's Cave Eleuthera Bahamas AHC Bahamas Technical Report Lighthouse Point were ecofacts and | poster |
An International Plant Sentinel Network as an early-warning system; research on future pest threats (IPSN II) Funding Mixed funding mechanism: Non-competitive and virtual pot. Each funder only pays for the participation of their own national researchers, in certain cases after national selection. Total funding € 440 000 ca. Picture 1 Picture 1 Picture 1 Goals The IPSN’s overall goal is to act as an early warning system for new and emerging plant pests and diseases; providing information that can help mitigate the impacts of such organisms or prevent their introductions altogether. In order to do this, the IPSN will utilise its already established network of botanic gardens, arboreta, plant protection scientists and National Plant Protection Organisations (NPPOs) as well as the tools and resources developed in the previous project. Research consortium DEFRA (GB), BMLFUW (AT), FPS (BE), CISTA (CZ), BMEL (DE), CREA (IT), SASA (GB), APHIS (USA), UNITUS (IT), UdL (ES), PHA (AU), UCPH (DK), CABI (GB), BBB (NZ), SLU(SE), CABI (CH), SDU (TR) Contact information Project coordinator: Katherine O’Donnel katherine.odonnell@bgci.org Key outputs and results • Key training and standardised surveying materials aimed at supporting garden staff with the opportunity to explore utilisation by a wider range of stakeholders. • European and international workshops in Euphresco partner countries and prioritised areas around the world. • Best practice and general support for botanic gardens and arboreta wishing to run citizen science projects or education programmes. • An electronic reporting system and front-facing database to track changes in plant health and gather information to enhance early detection and/or risk assessments. • Maps illustrating the distribution of gardens, host species and pest species. • Sentinel research projects for priority organisms and priority host species. Objectives • Enhanced early detection of new and emerging pests and diseases; including known and unknown organisms. • The project will support Pest Risk Analysis (PRAs) through research coordination and evidence gathering to address knowledge gaps to support PRA activities. • The establishment of a self-sustainable network. 01/2017-12/2019 | poster |
Renewable Energy Generation Expansion Pathways for Cameroon Yvan Ayuketah, Marilyn Bongmo 1 Regional Center for Energy and Environmental Sustainability (RECEES), Ghana. 2 Ministry of Water Resources and Energy, Cameroon 1. Context Contact: Yvan Ayuketah: yvanayuketah@gmail.com ; Marilyn Bongmo:bimewoman1gmail.com 5. Policy insights, conclusions and future work 3. Methods & Scenarios 2. Aim • Cameroon has a population of 25.88 million and GDP of $39.50 billion in 2020 [1]. • The nation aims to reduce its dependence on hydropower and diversify its energy mix. • its Nationally Determined Contributions (NDCs) aim to reduce emissions by 32% in 2035 [3]. • With developmental goals greatly hindered by inadequate power generation, the nation seeks increase thermal generation and renewables to increase its 70% access rate [4]. • Cameroon aim to ensure a 25% share of renewables in the generation mix by 2035. This would also increase energy its security [5]. • The OSeMOSYS, an open-source integrated least-costs energy model was used with clicSAND as the modelling interface. • The key assumptions and data sources were gotten from [4] • Modelling period was from 2020 to 2050 • Three scenarios were developed for Cameroon: (i) The business-as-usual (BAU) • No obligation to meet the energy diversity, RE and other energy sector targets in masterplans such as Vision 2035, the Development Project of the Energy Sector (PDSEN) and the Rural Electrification Master Plan (REMP) [4]. • No constraints on generation system emissions. (ii) NDC scenario • 25% and 45% RE target by 2035 and 2045 respectively • Reduced dependence on hydropower • No constraints on emissions (ii) Net-zero scenario • Zero electricity sector emissions by 2050. • Reduced dependence on hydropower. 4. Results 6. References • To evaluate the least-cost optimal generation expansion pathway up to 2050 for Cameroon under current trends and no policy intervention. • To determine the optimal generation expansion pathway that attains a 25% and 45% renewable energy share by 2035 and 2050 respectively. • To evaluate the optimal generation expansion pathway for Cameroon that achieves net-zero emissions by 2050. Conclusions: • Continuous reliance on Hydropower for over 75% of generation mix in the BAU scenario, • The 25% RE target in the NDC is not enough to reduce dependence on hydropower. However, attaining a 45% target by 2050 significantly reduces this dependence. • Its possible to transition to net-zero in Cameroon due to the small contribution of fossil fuels Policy insights • An intervention is needed to reduce Cameroon’s dependence on hydropower for increased energy security. • Priority and incentives should be allocated to renewables. This would enable them phase out fossil fuels in the generation mix. Future work • Asses the flexibility of power system under higher penetrations of RE. • Investigate the impact on increased RE penetration on the stability an reliability of the power system. • Investigate the impact of carbon pricing and emission trading in the power system. JOINT SUMMER SCHOOL ON MODELLING TOOLS FOR SUSTAINABLE DEVELOPMENT | 2022 Figure: The map of Cameroon. Source [4] A Cost-benefit analysis of Policy, Programs and Projects (C3PO) that is Retrievable, Reusable, Repeatable, Reconstructible, Interoperable and Auditable (u4RIA) [1] World Bank, "Cameroon Development Indicators," The World Bank Group, 2022. [Online]. Available: https://data.worldbank.org/country/cameroon. [Accessed 9 June 2022]. [2] MINEPDD, "Intended Nationally Determined Contribution (INDC)," 29 July 2016. [3] IEA, "World Energy Outlook 2020," International Energy Agency, Paris , 2020. [4] KEEI, "A Study for Establishment of the Master Plan of Renewable Energy in Cameroon" Korea Energy Economics Institute, Ulsan, 2017. [5] Allington, et al, "Selected ‘Starter Kit’ - Energy system modelling data for Cameroon (#CCG)," Research Square, pp. 1-15, 2021 0 50 100 150 200 250 2015 2016 2017 2018 2019 2020 2021 | poster |
Research data services in academic libraries: the essential list Ana Doñate-Cifuentes1, Fernanda Peset2, Antonia Ferrer-Sapena2, Consol García3 1Universidad CEU Cardenal Herrera, València, Spain; 2Universitat Politécnica de València, Spain; 3Universitat Politécnica de Catalunya-Barcelona Tech, Spain; consol.garcia@upc.edu Our objective: study about research data services in this type of library settings (America and Europe). Previously, the Carol Tenopir’s team reviews the situation in North America and Canada. The aim of our work is to build a list with the essential data services for the small libraries with a little budget, and describe the European situation. Acknowledgements: Wolfram Horstmann, Carol Tenopir, Imma Subirats and Eulàlia Serveto. Conclusion: The three essential services that all the academic libraries must offer as default are: consulting with faculty, staff or students on data management plans and metadata standards, and preparing data sets for deposit into a repository. Method: select the best institutions by bibliography and expert opinion, and the medium by regional criterion and DOAR review; check their web sites looking for the RDS; classify them by Tenopir’s team work. Consulting with faculty, staff or students on data management plans (costs, standards, storage...) Consulting with faculty, staff or students on data and metadata standards. Preparing data / data sets for deposit into a repository (formats, organizing, documentation, legal aspects, integrity,...) Providing technical support for research data services (RDS) systems (e.g., a repository, access and discovery systems) where can I release my data? Providing reference support for finding and citing data / data sets. Creating web guides and finding aids for data / data sets / data repositories. Identifying data / data sets that could be candidates for repositories on or off campus Creating data or transforming metadata for data or data sets. Discussing research data services (RDS) with other librarians, or other people on campus, or RDS professionals on a semiregular frequency. Deaccessioning / deselection of data / data sets for removal from repository Outreach and collaboration with other research data services (RDS) providers either on or off campus. Directly participating with researchers on a project (as a team member). Training coworkers in your library, or across campus, on research data services (RDS). 0000-0001-5708-8902 0000-0001-6432-917X 0000-0003-3706-6532 0000-0001-8085-0088 10 services 8 services 8 services 8 services 7 services 6 services 6 services 6 services 6 services 2 services Expert criterion: DOAR criterion: 6 services 5 services 4 services 3 services | poster |
Eleanor J. Junkins1, Katharine M. N. Lee2, & Kathryn B. H. Clancy3,4 1 Department of Psychology, College of LAS, UIUC; 2 Division of Public Health Sciences, Washington University in St. Louis; 3 Department of Anthropology, UIUC; 4 Beckman Institute, UIUC Enhancing Knowledge through Engagement: Participation in an Unpaid Survey-Based Health Research Acknowledgments This research was supported in part by the University of Illinois Beckman Institute for Advanced Science and Technology, the University of Illinois Interdisciplinary Health Sciences Institute and the University of Illinois Center for Social & Behavioral Science Small Grant Program. Contact Me junkins2@illinois.edu References 1. Borno, H., Siegel, A., & Ryan, C. (2016). The problem of representativeness of clinical trial participants: Understanding the role of hidden costs. Journal of Health Services Research & Policy, 21(3), 145–146. 2. Kennedy-Martin, T., Curtis, S., Faries, D., Robinson, S., & Johnston, J. (2015). A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results. Trials, 16(1), 495. 3. Gobat, N. H., Gal, M., Butler, C. C., … & Nichol, A. (2018). Talking to the people that really matter about their participation in pandemic clinical research: A qualitative study in four European countries. Health Expectations, 21(1), 387–395. 4. Chin, L. J., Berenson, J. A., & Klitzman, R. L. (2016). Typologies of Altruistic and Financial Motivations for Research Participation: A Qualitative Study of MSM in HIV Vaccine Trials. Journal of Empirical Research on Human Research Ethics, 11(4), 299–310. 5. Sober, E. (1988). What Is Evolutionary Altruism? Canadian Journal of Philosophy Supplementary Volume, 14, 75–99. https://doi.org/10.1080/00455091.1988.10715945 6. Lee, K. M., Junkins, E. J., Fatima, U. A., Cox, M. L., & Clancy, K. B. (2021). Characterizing menstrual bleeding changes occurring after SARS-CoV-2 vaccination [Preprint]. Obstetrics and Gynecology. 7. R Core Team. (2022). R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing. 8. Silge, J., & Robinson, D. (2016). tidytext: Text Mining and Analysis Using Tidy Data Principles in R. JOSS, 1(3). 9. Hvitfeldt, E. (2020). textdata: Download and Load Various Text Datasets. 10. Grün, B., & Hornik, K. (2011). topicmodels: An R Package for Fitting Topic Models. Journal of Statistical Software, 40(13), 1–30 Conclusions It is evident that people found the survey through a variety of means and trusted sources. Many described googling for their symptoms and found our study. Altruistic motives, including existential, vernacular, and political, were apparent from this analysis. The implication of this work is that responsive, flexible post-clinical trial survey research with lower barriers of participation may be possible and may be able to reach people more widely. It may also serve to create active communication between scientists and the public to keep everyone informed of post-vaccine experiences. Future clinical trial research can be informed by attention to the large range of symptoms experienced by people. Aims 1) How did people hear about the study? 2) What were people’s interest in the study? 3) How do these interests relate to altruistic motivations of participation? Data Survey Instrument Demographics include age, country of birth, gender, race, and ethnicity. Open-ended text responses: • How did you hear about this project? • What is your interest in this project? Sample Data was derived from a large, online mixed-methods survey on menstruation and vaccine side-effects following COVID-19 vaccination6 (N~102,000). The current sample was limited to people in the USA who responded to both these questions in English. • N= 22,737 • Age M=33.7 years (SD=9.8) • 90.4% cisgender women; 83.4% white; 81.6% non- Hispanic Introduction Health research—and more specifically clinical trials for vaccines—is oft | poster |
Most biological models are composed of single-compartment neurons. Despite recent findings on dendritic computational properties, these features have been only rarely exploited [1]. We introduce a multi-compartment model for pyramidal neurons [2], in which bursts and dendritic input segregation allow for biologically plausible target-based learning [3]. The solution of a problem is represented as a spatio-temporal pattern of bursts, suggested to apical tufts of neurons. A store-and-recall and a nontrivial navigation tasks are learned, the latter by introducing a hierarchical architecture of layers enabling the decomposition into simpler subtasks (hierarchical imitation learning) [2]. Acknowledgements This work has been supported by the European Union Horizon 2020 Research and Innovation program under the FET Flagship Human Brain Project (grant agreement SGA3 n. 945539) and by the INFN APE Parallel and Distributed Computing Laboratory. References [1] Payeur, Guerguiev, Zenke, Richards, Naud. Nature neurosci. (2021) 24, 1010. [2] Capone, Lupo, Muratore, Paolucci. arXiv (2022) 2201.11717. [3] Muratore, Capone, Paolucci. PloS one (2021) 16(2), e0247014. Cosimo Lupo*,1, Cristiano Capone*,1, Paolo Muratore2, Pier Stanislao Paolucci1 1 INFN, Sezione di Roma, Rome, Italy — 2 SISSA, Trieste, Italy. * These authors contributed equally to the work. Burst-dependent plasticity and dendritic amplification support target-based learning and hierarchical imitation learning Coincidence mechanism • Somatic spikes open a window • Apical spikes within the window create the coincidence • Result is a burst activity Store-and-recall task • Learn a target 3D trajectory • After many presentations: - Internal bursting activity spontaneously reproduced - Accurate output (mse ~10-2) Target-based learning Soma+distal internal bursting activity is the target, soma+proximal bursts have to reproduce it: Multi-compartment pyramidal neuron • Dendritic segregation • Apical proximal compartment for recurrent synapses from other neurons • Apical distal compartment for target and context signals Apical context as target selector • Desired target is selected by the context • Successful target recover even after apical context switch-off or corruption through noise • Basal context has no such robustness Hierarchical architecture • High network: - task-selecting output as context for low network • Low network: - task-actuation output, selected by injected context Hierarchical imitation learning • Manager/worker architecture is able to solve the task • High network learns which task to solve • Low network learns how to reach the target (button or food) • Learning on ~100 button/food examples Performances • Test is done in closed loop • Button reaching rate ~100% • Apical context crucial for hierarchical decomposition (basal context not able to properly assign the task) Button-and-food task • First reach the button and unlock it; then reach the food • Reaching food in first place gives no reward • Button/food positions are random Contacts Email: cosimo.lupo89@gmail.com Conclusions • Target-based learning is an alternative to error-based approaches, offering several advantages • Bursts and dendritic segregation naturally support it • Target-based learning also allows to successfully implement hierarchical policies boosting Hierarchical Imitation Learning Future outlooks • Effects of sleep (replay of burst patterns and performance improvement) arXiv preprint Accepted in ICML 2022 | poster |
@M4ESTRO_Project M4ESTRO EU Project www.m4estro-project.eu Technology Transfer Syst Resilient, transparent and flexible manufacturing processes in value chains A holistic framework based on 4 pillars Resilient equipment, AI and trusted data for adaptive manufacturing Resilient Simulations to the Industrial Metaverse for responsive manufacturing Human centered Manufacturing Resilience and Sustainability 17 Partners - 8 Countries - 42 Months – 6 Million Euros in funding Strategies and models for flexible, resilient, and reconfigurable value networks through Trusted and Transparent Operations Industrial Manufacturing As a Service | poster |
Participación e involucramiento de madres de preescolares cuando usan conjuntamente dispositivos móviles. PhD(c) Rodrigo Arroyo (rarroyob@udd.cl) Doctorado en Ciencias del Desarrollo y Psicopatología Estudio Dos Situación experimental Introducción N=30 díadas EG Lúdico Contexto inducido El uso conjunto (Joint media engagement, JME10) refiere a los momentos cuando 2 o más personas (la madre e hijo/a) se acompañan y comparten mientras alguno de los dos (o ambos) ve, reproduce, busca, lee, juega o crea en el dispositivo. La evidencia sugiere que JME es una forma de aumentar el impacto positivo derivado de dicho uso, tanto para el desarrollo de los niños como para la relación entre madres e hijos. 11,12,13,14 Reportes internacionales muestran que las instancias JME se desarrollan principalmente en medios tradicionales (TV, libros), con un 63% de padres que refieren JME-DM15. Al explorar los predictores de JME-DM, se han analizado las características sociodemográficas (edad, educación), uso y experiencia de uso materna de DM5, junto con el sistema de creencias que enmarca y se traduce en las prácticas parentales16,18,19. La evidencia muestra una fuerte relación con el contexto cultural18, así como el peso de otras influencias marco, tal como la relacionadas al juego digital y la participación materna19. Los dispositivos móviles (DM) como los teléfonos inteligentes y las tabletas se han vuelto una parte integral en nuestro día a día. La adopción de estos dispositivos en nuestro país muestra que el 92% de los hogares con niños entre los 9 y 17 años cuenta con télefono inteligente y el 50% con una tableta1, aunque no contamos con datos que visualicen el uso por población preescolar. La experiencia internacional apunta que los niños acceden a tecnologías a menor edad y con mayor frecuencia que las generaciones anteriores2. Estos dispositivos son atractivos, fáciles de usar por niños preescolares3, sensibles al tacto4, portátiles5 y proveen una respuesta contingente e interactiva 6,7. Junto con la abundante oferta de contenidos y actividades disponibles a través de las aplicaciones (apps)6, explican parcialmente que los padres usen esta tecnología para que sus hijos aprendan y se entretengan. Si bien ha sido establecido que las conductas parentales y la cualidad de la interacción padres e hijos moldean de manera crítica el desarrollo infantil8,9, existe poca investigación que investigue como cambia el rol de los padres cuando interactúan con sus hijos durante el uso conjunto de DM5. 1. ¿Cuál es la frecuencia de JME-DM en Chile? 2. ¿Cuál es la relación entre los factores sociodemográficos, las creencias y la frecuencia de JME-DM? 3. ¿Difiere la interaccion madre-hijo/a en sesiones JME- DM dependiendo del contexto inducido por el investigador? Preguntas de Investigación Estudio Uno Encuestas Metodología Referencias Madres >18a con hij@ 4a Al menos un DM en casa N=359 Tamaño Criterio de exclusión Datos socio demográficos Cuestionario uso de TD y creencias relacionadas Patient Health Questionnaire (PHQ-9) Escala de involucramiento Temperamento niño (surgencia, CBQ-vsf) N=60 díadas N=30 díadas EG Educativo 10’ minutos video grabados JME-DM “usen el DM tal como típicamente lo harían en su hogar cuando quieres que tu hijo/a [juegue/ aprenda] con la tableta.” Fidelidad Interacciones madre e hijo: Contenido Positivo (andamiaje) y Negativo (intrusión) Afecto Positivo y Negativo Responsividad al niño Compromiso en la tarea Verbalizaciones Playfullness madre Interacciones hijo a madre: Afecto Positivo y Negativo Responsividad a la madre Compromiso en la tarea Verbalizaciones • Madres de mayor edad • Con mayor años de educación • Con más uso de DM • Más involucradas en la vida del niño • Creencias positivas relativas al uso de DM Frecuencia JME-DM (+) (+) (+) (-) • Madres que creen que su hijo es “nativo digital” Participación de las madres en JME-DM 1 Cabello, P., Claro, M., Lazcano, D., Cabello-Hutt, T., Antezana, L., & Ochoa, J. M. (2017). Implem | poster |
Context Questions Methods Step 1. We used modeling and simulation to predict the crop phenotypic plasticity resulting from the interaction of plant traits, climatic variability and management actions. e SUNFLO crop model [1,2] was parameterized for 35 recent oleic and linoleic sunflower cultivars. e values of the genotype-dependent parameters were obtained by measuring 10 phenotypic traits in dedicated field platforms (2 locations per year) or controlled conditions [3,4]. Variety assessment is a key component of crop performance improvement (e.g. potential yield, quality, disease resistance, abiotic stress tolerance, environmental benefits) and this process is still largely based on experimental approaches in field. Plant phenotyping and crop modeling open the possibility to predict crop performance in agricultural conditions that are not tested in the variety assessment chain, yet which can occur in the target population of environments. Our objective is to present an integrated framework for variety assessment based on crop modeling in order to widen and complete the current informations on varieties provided by national advisory services or extension services for a large range of environmental and agronomic conditions. e potential use of this framework will be illustrated on sunflower crop as a proof of concept. Results Figure 1. Design of the MET used for model evaluation. First, we phenotyped newly released hybrids varieties in independent trials in field and controlled conditions to set up the genotype-dependant parameterization of the crop model. en, we evaluated SUNFLO prediction capacity on the MET (relative RMSE for oil yield: 15.8%) and its capacity to rank those commercial hybrids (Kendall’s tau = 0.39, p < 0.01) for oil yield. We also tested the model capacity to simulate GxE interactions in the numerical experiment (step 3) by comparing two nested linear mixed models differing by the interaction term (LRT: χ2(482) = 3561, p < 0.001, interaction model was a better fit). Additionally, we showed that the SUNFLO crop model could provides indicators of the crop exposition to abiotic stress, which could be used to explain yield variance (Figure 3). ‣ How to leverage crop modeling to improve the assessment and recommendations for new varieties ? ‣ Can we recommend varieties to reduce phenotype-environment mismatch in the targeted cropping area ? Figure 2. A four step approach to include crop modeling in the variety recommendation process. e representation of the variety assessment chain (upper part in the diagram) is based on the current French system, with two years on trials before variety release (variety evaluation MET), and two year aer (agricultural extension MET). e presented approach leverage existing trials to get informations on tested varieties and to evaluate the crop model (steps 1-2). Aer designing numerical experiments, simulation would then provides recommendation for variety choice, accounting for growing conditions and climatic uncertainty (steps 3-4). e simulation of phenotypic plasticity makes possible a set of applications in variety assessment for breeders and advisers [5]: ‣ e characterization of abiotic stress as perceived by plants in each trial environment, providing that few control genotypes are included. ‣ e benchmarking of performance for material registered in different years, i.e. having experienced distinct climatic conditions. ‣ e determination of agronomic suitability of released varieties, and especially their suitability to drought-prone areas and the optimal management for each variety type. Conclusions and perspectives References and contact 1. Casadebaig P, Guilioni L, Lecoeur J, Christophe A, Champolivier L, Debaeke P. SUNFLO, a model to simulate genotype-specific performance of the sunflower crop in contrasting environments. Agricultural and Forest Meteorology. Elsevier; 2011;151: 163–178. doi:10.1016/j.agrformet.2010.09.012 2. Lecoeur J, Poiré-Lassus R, Christophe A, Pallas B, | poster |
Faculty of Polymer Techology • Ozare 19, SI-2380 Slovenj Gradec • M: +386 31 339 985 • W: www.ftpo.eu Understanding the bonding strength of hybrid-produced thermoplastic composites to enable homogenous recycling T. Stiller a, J. Slapnik b, B. Zink c, C. Wick d, J. Vidal e, R.C. Kerschbaumer a a Polymer Competence Center Leoben GmbH, Leoben, Austria | roman.kerschbaumer@pccl.at INTRODUCTION Nowadays the development of technologies leads to more possibilities regarding applications and properties. Especially the progress of existing technologies enables the production of high-performance composite structures with recyclable thermoplastic matrices. By combining different processing technologies, a hybrid-produced part joins their advantages. Nevertheless, by combining materials and technologies the path at end of life usually ends in thermal recycling. Without doubt this is a waste of resources, since thermoplastic components can be easily recycled if separated correctly. RESULTS REFERENCES 1 A. Szuchács et al. (2022) Bonding strength calculation in multicomponent plastic processing technologies, Mater. Manuf., 37:2, 151-159, DOI: 10.1080/10426914.2021.1948052 2 Gašper Tič, Influence of processing parameters and surface roughness on the adhesion between overprinted thermoplastic polyurethane components and injection molded polyamide plates, Master thesis (2023) IPPT_TWINN | July 2023 www.ippt-twinn.eu IPPT_TWINN - Reinforcing the scientific excellence and innovation capacity in polymer processing technologies of the Faculty of Polymer Technology ACKNOWLEDGEMENT: This research was funded by the Horizon Europe Framework Program and the call HORIZON-WIDERA-2021-ACCESS-03, under the grant agreement for project 101079051 – IPPT_TWINN. b Faculty of Polymer Technology, Slovenj Gradec, Slovenia c Budapest University of Technology and Economics, Budapest, Hungary d Eastern Switzerland University of Applied Sciences, Rapperswil, Switzerland e AITIIP Technology Center, Zaragoza, Spain METHODOLOGY Within the IPPT_TWINN project it is the goal to manufacture thermoplastic composites via hybrid technologies as thermoplastic resin transfer molding (T-RTM) [1], injection molding (IM), and additive manufacturing (AM). Not only technologies are combined, but also materials such as polyamide and thermoplastic elastomers, to adapt properties locally, e.g., the bonding strength. Especially AM enables the individualization of parts. Therefore, AM will be applied to print structures or geometries on test specimens manufactured via the T-RTM and IM technology . To study the correlations between printing parameters and bonding strength, a mathematical model is developed [2]. Finally, the bonding strength is tested by fracture mechanical approaches. These tests provide information of the maximum bonding strength and, hence, the required energy to separate the materials from each other. By this, the separated materials can be recycled in a homogenous material stream to raw material and, thus, reused. Manufacturing Testing (A) Production of parts with hybrid technologies and different material combination (B) Investigation of dominant parameters for bonding strength with different testing methods (C) Successful separation of material combinations can be introduced to recycling cycle (A) (B) (C) 𝑴𝑝𝑟𝑜𝑐𝑒𝑠𝑠, 𝑚𝑎𝑡𝑒𝑟𝑖𝑎𝑙, 𝑐𝑜𝑚𝑏𝑖𝑛𝑎𝑡𝑖𝑜𝑛+ 𝑻𝐴(𝑣, 𝑇, 𝑝, … ), 𝐵𝑣, 𝑡, 𝐹, 𝑇, . . . , 𝐶 = 𝑄(ℎ𝑦𝑏𝑟𝑖𝑑𝑝𝑎𝑟𝑡) CONCLUSION The correlation between bonding strength and the single parameters, follows a polynomial function, with an optimum in bonding strength for a special parameter setting. This correlation defines the hybrid part quality. By combining different settings optimums at a similar level can be achieved. Further tests are planned to include more processing parameters. Considering this information, composite parts can be optimized in the bonding but furthermore separated to ensure a homogenous recycling stream which is necessary to keep the quality of recycled material. Thermoplast | poster |
In July 2013, the Becker Medical Library at Washington University in St. Louis held a workshop for librarians on the Becker Model, a framework developed by research assessment librarians for quantifying medical researchers' individual and group outputs. Following the workshop, the Becker Model was analyzed for content to adapt it to the physical sciences. This poster presents the process and results of applying their model to the curriculum vitae of a Yale University astronomy professor. ABSTRACT • Examine commonalities and differences between medical and physical sciences fields regarding research impact. • Review literature on scholarly assessment in astronomy to determine the types of assessment that matter. • Apply the Becker Model to citation data and ancillary CV data of an astronomy faculty member at the institution as a proof-of-concept for adapting the Model. • Create a program for research impact workshops to address a diverse physical, life, and social sciences clientele. OBJECTIVES Borne, K. (2001). Data mining in astronomical databases. Mining the Sky, 671–673. doi: 10.1007/10849171_88 Bornmann, L., & Daniel, H. (2009). The state of h index research: Is the h index an ideal way to measure research performance? EMBO Reports, 10(1). doi:10.1038/embor.2008.233 Fortson, L., Masters, K., Nichol, R., Edmondson, E. M., Lintott, C., Raddick, J., Schawinski, K., & Wallin, J. (2012). Galaxy Zoo. In M. J. Way, J. D. Scargle, K. M. Ali, & A. N. Srivastava (Eds.), Advances in Machine Learning and Data Mining for Astronomy (pp. 213–236). Boca Raton, FL: CRC Press. doi:10.1201/b11822-16 Garfield, E. (1979). Is citation analysis a legitimate evaluation tool? Scientometrics, 1(4), 359–375. doi:10.1007/BF02019306 Ginsparg, P. (2011). ArXiv at 20. Nature, 476(7359), 145–7. doi10.1038/476145a Harley, D., Acord, S. K., Earl-Novell, S., Lawrence, S., & King, C. J. (2010). Assessing the future landscape of scholarly communication: An exploration of faculty values and needs in seven disciplines. Berkeley, CA. Retrieved from https://escholarship.org/uc/item/15x7385g.pdf Havemann, F., & Larsen, B. (2014). Bibliometric Indicators of Young Authors in Astrophysics: Can Later Stars be Predicted? arXiv Preprint, 1–14. arXiv:1404.3084 Hourclé, J. A. (2012). Advancing the practice of data citation : A to-do list. Bulletin of the American Society for Information Science and Technology, 38(5), 20–22. Retrieved from http://www.asis.org/Bulletin/Jun-12/ JunJul12_Hourcle.pdf Jamali, H. R., & Nicholas, D. (2009). E-print depositing behavior of physicists and astronomers: An intradisciplinary study. The Journal of Academic Librarianship, 35(2), 117–125. doi:10.1016/j.acalib.2009.01.005 Kousha, K., Thelwall, M., & Rezaie, S. (2010). Can the impact of scholarly images be assessed online? An exploratory study using image identification technology. Journal of the American Society for Information Science and Technology, 61(9), 1734–1744. doi:10.1002/asi.21370 Larivière, V., Sugimoto, C. R., Macaluso, B., Milojević, S., Cronin, B., & Thelwall, M. (2014). arXiv E-prints and the journal of record: An analysis of roles and relationships. Journal of the Association for Information Science and Technology, 65(6), 1157–1169. doi:10.1002/asi.23044 Lawrence, B., Jones, C., Matthews, B., Pepler, S., & Callaghan, S. (2011). Citation and peer review of data: moving towards formal data publication. The International Journal of Digital Curation, 6(2), 4–37. Lozano, G., Larivière, V., & Gingras, Y. (2012). The weakening relationship between the Impact Factor and papers’ citations in the digital age. arXiv Preprint, 2140–2145. doi:10.1002/asi Penfield, T., Baker, M. J., Scoble, R., & Wykes, M. C. (2013). Assessment, evaluations, and definitions of research impact: A review. Research Evaluation, 23(October 2013), 21–32. doi:10.1093/reseval/rvt021 Pepe, A., & Kurtz, M. J. (2012). A measure of total research impact independent of time and discipline. PloS One, 7(11), e46428. do | poster |
METHODS Three different protocols were tested: ▪Horse constitutes an important veterinary patient and a relevant animal model owed to their physiopathological analogies with human. ▪MSCs are promising therapy for several diseases, including musculoskeletal disorders. ▪However, MSCs present several drawbacks → senescence in culture and require repeated tissue harvesting: more heterogeneity and invasive procedures. ▪To increase MSC availability and reduce invasive procedures, it is possible to derive MSCs from iPSCs → iMSCs. ▪While human iMSCs are being intensively studied, only two equine studies have reported the generation of eiMSCs to date (Lepage et al., 2016 and Chung et al., 2019). INTRODUCTION Derivation of equine induced Mesenchymal Stem Cells (eiMSCs) from equine induced Pluripotent Stem Cells (eiPSCs): a promising step for veterinary and translational regenerative medicine María Belén Serrano1, Elvira Bernad1, Alina Cequier1,2, Francisco José Vázquez1,2, Antonio Romero1,2, Arantza Vitoria1,2, Pilar Zaragoza1, Clementina Rodellar1, Laura Barrachina1,2 (1) Laboratorio de Genética Bioquímica LAGENBIO – Instituto Agroalimentario de Aragón – IA2 (Universidad de Zaragoza – CITA) – Instituto de Investigación Sanitaria de Aragón (IIS), Zaragoza, Spain (2) Servicio de Cirugía y Medicina Equina, Hospital Veterinario, Universidad de Zaragoza, Zaragoza, Spain Contact: lbarrach@unizar.es RESULTS ➢Deriving eiMSCs from eiPSCs is feasible and these could be established as an interesting alternative to eMSCs. ➢We have detected some differences in eiMSCs among lines and compared to eMSCs, such as immunophenotype and their differentiation potential, mainly for chondrogenesis. However, variability of eMSCs has also been noted among tissue sources and between individuals. ➢Further studies are needed to analyse eiMSCs properties and immune function to improve cell therapies under One Medicine perspective. CONCLUSIONS Cell culture Spontaneous differentiation Directed differentiation ABBREVIATIONS: DMEM LG = Dulbecco`s Modified Eagle`s Medium Low Glucose; FBS = Fetal Bovine Serum; L-glut = L-glutamine; S = Streptomycin; P = Penicillin; VTN = Vitronectin; SB431542 = TGF-β receptor kinase inhibitor; bFGF = basic Fibroblast Growth Factor; eiNCCs = equine induced Neuro Crestal Cells; CDM = Chemically Defined Medium; CHIR99021 = GSK-3α/β inhibitor; AF = Attachment Factor; MEFs = Mouse Embryonic Fibroblasts; EGF = Epidermal Growth Factor. To obtain eiMSCs and compare their main characterization criteria over primary equine MSCs (eMSCs). OBJECTIVE PROTOCOL 3. Differentiation via neural crest pathway →3 stages PROTOCOL 1. Switch to MSC media Chung et al., 2019 PROTOCOL 2. Switch to specific differentiation media Lepage et al., 2016 Immunophenotype (flow cytometry) Trilineage differentiation Gene expression (qPCR) PID2020-116352GB-I00 The first 2 passages →VTN; next passages →tissue-treated culture plate DMEM LG 10% FBS 2mM L-glut 0.1 mg/mL S 100 U/mL P 10 µM SB431542 5 ng/mL bFGF The first 2 passages →VTN; next passages →tissue-treated culture plate The first 10 days of culture DMEM LG 10% FBS 2mM L-glut 0.1 mg/mL S 100 U/mL P 20 ng/mL bFGF The first 2 passages →VTN; next passages →tissue-treated culture plate CDM 10 µM SB431542 1 µM CHIR99021 VTN; 4 passages AF + MEFs; 10 days CDM 10 µM SB431542 20 ng/mL bFGF 20 ng/mL EGF 1. eiNCCs induction 2. eiNCCs expansion 3. eiMSCs induction Ctrl C A O Ctrl = control culture A = Adipogenic differentiation C = Chondrogenic differentiation O = Osteogenic differentiation Ctrl C A O eiMSCs line 1 eiMSCs line 3 eiMSCs line 2 Ctrl C A O Reference sample →each eiPSCs line PROTOCOL 1 eiPSCs eiPSCs PROTOCOL 2 1. eiNCCs induction 2. eiNCCs expansion 3. eiMSCs induction PROTOCOL 3 eiPSCs line 1 eiPSCs line 2 eiPSCs line 3 eiMSCs line 1 eiMSCs line 2 eiMSCs line 3 Fukuta et al., 2014; Chijimatsu et al., 2017; Nakamura et al., 2021; Kamiya et al., 2022 Bone marrow eMSCs DMEM LG 10% FBS 2mM L-glut 0.1 mg/mL S 100 U/mL P C | poster |
Our Advisory Board, collaborators and adopters include: BioSharing is a web-based, searchable portal of 3 interlinked registries, containing both in-house and crowd-sourced curated descrip?ons of standards, databases and data policies. Indicators of readiness and use highlight mature standards and databases endorsed by data policies from journals and funders. It’s so simple and quick to register your resource. Go to biosharing.org/new to get started. | poster |
NOAA STAR SOCD OceanView: The Level-4 thermal fronts module Prasanjit Dash1,2, Marouan Bouali3, Jorge Vazquez4, Paul DiGiacomo1 1NOAA STAR SOCD, College Park, MD, USA; 2CSU CIRA, Fort Collins, CO, USA; 3IOUSP, São Paulo, Brazil; 4JPL/Caltech, Pasadena, CA, USA Preamble: The NOAA STAR SOCD OceanView (OV) v1.0 was publicly released in May-2021 at https://www.star.nesdis.noaa.gov/socd/ov/. The OceanView is a web-based application delivering an integrated display of remote sensing, in situ, and model data over oceans, polar areas, and coastal and inland waterways [1]. It incorporates products primarily from NOAA and some from NASA and other sources. The application comprises several modules, including an experimental thermal fronts component capable of deriving and interactively visualizing level-4 SST fronts. This L4 fronts module will potentially contribute to the GHRSST Climatology and L4 Inter-comparison Task Team (IC-TT) in discussion with its participants and other enthusiasts. Here, we demonstrate the existing capability with only one L4 SST and aim to gauge features of interest and potential extension to meet GHRSST TT objectives. S3. Calibration, validation and product assessment Abstract ID 42; virtual The Satellite Oceanography and Climate Division (SOCD) of NOAA STAR released the OceanView v1.0 in 2021. The L4 fronts module of OceanView currently has only one L4 SST front (NOAA GOES-POES blended). However, the system is scalable and will be expanded depending on identified needs and the path forward. This preliminary illustration aims to gauge features of interest and potential extension to meet GHRSST IC-TT objectives. The work is experimental and will likely undergo improvements in both algorithm and validation approaches. References [1] Dash, P. and DiGiacomo, P, 2021: The NOAA STAR SOCD OceanView (OV): an application for integrated visualization of satellite, in situ, and model data & ocean events – the debut release.; GHRSST XXII Proc. Virtual meeting, 7-11 June 2021. https://doi.org/10.5281/zenodo.5750123 [2] Maturi, E., and Coauthors, 2017: A New High-Resolution Sea Surface Temperature Blended Analysis. BAMS, 77–80, 21–30, https://doi.org/10.1175/BAMS-D-15-00002.1 [3] Martin, M., and Coauthors, 2012: Group for High Resolution Sea Surface temperature (GHRSST) analysis fields inter-comparisons. Part 1: A GHRSST multi-product ensemble (GMPE). DSR. II, 77–80, 21–30, https://doi.org/10.1016/j.dsr2.2012.04.013 [4] Dash, P., and Coauthors, 2012: Group for High Resolution Sea Surface Temperature (GHRSST) analysis fields inter-comparisons. Part 2: Near real time web-based level 4 SST Quality Monitor. DSR. II, 77–80, 31–43, https://doi.org/10.1016/j.dsr2.2012.04.002 Acknowledgment JPSS program, Ocean Remote Sensing (funding); GHRSST IC-TT members for discussions. 23rd International Science Team Meeting (GHRSST XXIII), Barcelona 27 June – 1 July 2022 and virtual; contact: prasanjit.dash@noaa.gov (https://orcid.org/0000-0002-8789-0506) Simplified overview of: Science Technology Example Summary Experimental L4 front module • interactive profiler for individual fronts • filters for avg length, gradient & avg. SST 1. Calculate gradient values per pixel using finite difference, with central differences in the interior and first differences at the boundaries. 2. Use Sobel operator to detect edges. Canny was also tested (Marouan B.) but did not seem to provide significant improvement. Numerical operations 3. Adaptive threshold for Sobel filter using cumulative distribution function 4. Binarize to 1 or 0 using the above threshold 5. Skeletonize to make it thinner (1-pixel) 6. Contourize the detected edges (computer vision) Morphological operations 7. Store gradient values & location info for each point on the contours (for web interactivity) 8. Store average SST and length for each contour as attributes (for web interactivity) 9. Save all features in a GeoJSON file for web-display *These steps enable web-visualization & provide in | poster |
Одним из аспектов исследования режимов использования участков ЛПХ является оценка степени распаханности, базирующаяся на детектировании наличия и площади пашни, показывающая долю культивируемой пашни от общей площади участка. На участках ЛПХ выделены полигоны трёх классов: пашня, здания и сооружения, прочие объекты. По данным спутниковых снимков Sentinel-2 вычислены временные ряды индексов GNDVI, MCARI, MSI и NDMI, и их статистики за вегетационный период. Были обучены 4 модели машинного обучения – градиентный бустинг, деревья решений, случайный лес и метод опорных векторов. Классификация выполнена на уровне пикселей. Выбор классификационной модели на основе оценок точности по тестовой выборке. Итоговая предиктивная классификация всех участков территории выполнена методом градиентного бустинга который показал точность классификации выше остальных рассматривавшихся методов. Номер класса Метрики точности Градиентный бустинг (Gradient Boosting) Случайный лес (Random Forest) Дерево решений (Decision Tree) Метод опорных векторов (Support Vector Machines) Overall Accuracy 0.973 / 0.877 0.986 / 0.870 0.891 / 0.856 0.924 / 0.853 1 Producer’s Accuracy 0.984 / 0.984 0.959 / 0.973 0.928 / 0.963 0.981 / 0.992 User’s Accuracy 0.977 / 0.857 0.987 / 0.856 0.924 / 0.848 0.981 / 0.825 2 Producer’s Accuracy 0.954 / 0.656 0.976 / 0.664 0.864 / 0.634 0.840 / 0.584 User’s Accuracy 0.956 / 0.945 0.988 / 0.919 0.846 / 0.892 0.948 / 0.967 3 Producer’s Accuracy 0.934 / 0.712 0.935 / 0.680 0.584 / 0.696 0.677 / 0.560 User’s Accuracy 0.968 / 0.918 0.975 / 0.904 0.694 / 0.837 0.916 / 0.946 Распаханность 0.0 – 0.1 0.1 – 0.2 0.2 – 0.3 0.3 – 0.4 0.4 – 0.5 0.5 – 0.6 0.6 – 0.7 0.7 – 0.8 0.8 – 0.9 0.9 – 1.0 0.00 0-0.1 0.1-0.2 0.2-0.3 0.3-0.4 0.4-0.5 0.5-0.6 0.6-0.7 0.7-0.8 0.8-0.9 0.9-1 0.05 Доля участков Распаханность 0.10 0.15 Класс 1 – пашня (524 объекта) Класс 2 – иные земли (116 объектов) Класс 3 – здания и сооружения (177 объектов) а) Градиентный бустинг (Gradient Boosting) б) Дерево решений (Decision Tree) в) Случайный лес (Random Forest) г) Метод опорных векторов (Support Vector Machines) Распахиваемые земли Здания и сооружения Иные земли Степень распаханности: N – общее количество пикселей участка N1 – количество пикселей класса 1 (распахиваемые земли) R= N 1 N Оценка степени распаханности участка выполнена на основе попиксельной классификации как отношение количества пикселов, классифицированных как класс «пашня» к общему количеству пикселов участка, попадающего в полигон, выраженной в процентах. Результаты классификации были картированы с использованием цветовой шкалы степени распаханности от 0 до > 100%. На территории исследования по состоянию на 2022 год около 18% всех участков имеет распаханность менее 10%, низкий уровень распашки (от 0 до 20%) имеет около 30% участков, средний уровень (от 20 до 50%) – около 50% участков, около 20% участков имеет высокий уровень распашки (более 50%). Введение Методы Результат I Алгоритм обработки данных Выборка объектов Классификация Расчёт степени распаханности Оценка распаханности участков личных подсобных хозяйств с использованием методов машинного обучения по данным Sentinel-2 Артем Александрович Сабаев (artsab@yahoo.com), Елена Владимировна Понькина (ponkinaelena77@mail.ru) Алтайский государственный университет, Барнаул Территория — с. Кытманово, пос. Тягун, Кытманушка, Алтайский край Результат II Точность классификации, объекты тренинговой выборки/объекты тестовой выборки Разработанный инструментарий представляется перспективным для внедрения в систему мониторинга режимов использования участков ЛПХ на уровне сельских населенных пунктов, в частности детектирования пашни и забрасываемости участков. Анализ пространственных паттернов как и поиск факторов культивации пашни на участках ЛПХ в населенных пунктах представляет интерес для дальнейшего исследования. Заключение DOI: 10.5281/zenodo.14048405 | poster |
AN INTERNATIONAL CENSUS OF RESEARCH SOFTWARE IN INSTITUTIONAL ACADEMIC REPOSITORIES. This work expands on previous research, which examined 182 academic IRs from 157 universities in the UK¹. Few records of research software were found in IRs and the majority of IRs could not contain software as independent records of research output due to the underlying Research Information System (RIS) platform. Expanding on this work, similar analyses were performed on international IRs in what we believe is the first such census of its kind. 4,970 repositories from 125 countries were examined for the presence of software, along with repository-based metadata for potentially correlating factors. This will add evidence to the movement to recognise software as distinct and recordable research output in its own right. KEY RESULTS INTRODUCTION References [1] Carlin D, Rainer A, Wilson D. 2023. Where is all the research software? An analysis of software in UK academic repositories. PeerJ Comput. Sci. 9:e1546 http://doi.org/10.7717/peerj-cs.1546 [in press] [2] OpenDOAR. Online: https://v2.sherpa.ac.uk/opendoar/ CONCLUSIONS Dr. Domhnall Carlin | Centre for Secure Information Technologies, Queen’s University Belfast, N. Ireland. | d.carlin@qub.ac.uk No software search 50% Does not contain software 22.5% Error 19.9% Contains software 7.6% Analysis of repositories METHODOLOGY Source data were compiled from OpenDOAR², the directory of global Open Access Repositories. A list of institutional academic repositories was derived, providing URLs, country code and RIS platform. Each URL from 4,970 repositories across 125 countries was visited manually to search for research software. Each repository was categorised as one of: Contains software: software is a searchable item and the repository contains such records Does not contain software: software is a searchable item but the repository contains no such records No software search: software is not recognised as a specific item of output Europe 1856 America 1439 Asia 1364 Africa 214 Repositories per continent 0 500 1,000 1,500 2,000 2,500 dspace eprints weko digital commons Unknown islandora opus contentdm hal pure Top 10 RIS platforms Only 7.6% of IRs sampled globally contained software Around 30% could contain software Half did not recognise software as a discrete type of output Dspace accounts for nearly 40% of repositories Default config includes software as a type¹ However, 64.4% had no search item for software Defaults may have been removed A single word in a config file can allow software types (e.g. EPrints) Many IRs adopt Dublin Core Metadata format, but do not use defined vocab for types 1. Software is scarcely indexed in IRs 2. RIS platforms appear to have defaults altered 3. This may often be a policy issue, not a technical one FUTURE WORK Create a dedicated dashboard to monitor the change over time of software in IRs Automate the detection of software artefacts through lightweight and ethical harvesting Increase the coverage of the source data, particularly in underrepresented regions and countries Systematically clean the data using source code from repositories to provide metadata Use this evidence to inform policy lobbying initiatives Acknowledgements This work was supported as part of Dr Carlin’s UKRI EPSRC Research Software Engineering Fellowship (EP/V052284/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. | poster |
88 09-10 | 05 | 2019 Αθήνα | Ελλάδα 2019 ΕΛΕΒΙΤ - Ελληνική Εταιρεία Βιοϊατρικής Τεχνολογίας 2019 ELEVIT- Hellenic Society for Biomedical Technology c c PRELIMINARY RESULTS ON COMPUTERIZED ANALYSIS OF BOWEL SOUNDS CAPTURED FROM A NOVEL WEARABLE DEVICE V. Charisis*, S. Hadjidimitriou*, D. Iakovakis*, H. Placido da Silva**, S. Bostantzopoulou***, Z. Katsarou****, and L. Hadjileontiadis***** *Department of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, **PLUX Wireless Biosignals, Lisbon, Portugal, ***Third Neurological Clinic, G. Papanikolaou Hospital, Thessaloniki, Greece, ****Department of Neurology, Hippokration Hospital, Thessaloniki, Greece, *****Department of Electrical and Computer Engineering, Khalifa University of Science and Technology, Abu Dhabi, UAE vcharisis@ee.auth.gr, stellios22@gmail.com, dimiiako12@gmail.com, hsilva@plux.info, bostkamb@otenet.gr, katsarouzoe@gmail.com, leontios.h@kustar.ac.ae Abstract Bowel sounds (BS), the noises produced by the movement of fluids and gas during the peristaltic movement of intestines, are useful in clinical practice as their auscultation constitutes a traditional technique for identifying gastrointestinal (GI) health status. Assessing patients with GI disturbances presents many challenges for a health professional. In this direction, there are research efforts that focus on computerized BS analysis systems in order to detect GI motility problems. The aim of this work is to present an alternative technique to process BS, captured by a novel comfortable wearable device, namely smart belt, that captures 3-channel BS recordings at up to 3KHz sampling frequency, during a soda tolerance test (STT). The processing pipeline is applied separately on each sound channel and consists of two steps. At Step 1, the BS recordings are adaptively denoised via a wavelet transform-based stationary non-stationary filter (WTST-NST) [1] that separates sound events of interest (SEOI) from background noise. By applying the WTST-NST filter, the coherent structure of bowel sounds or other similar sound events (non-stationary) is revealed and separated from the superimposed interfering background noise (stationary). The output of Step 1 is subjected to time-frequency analysis based on the Continuous Wavelet Transform using the Morlet wavelet. The target is to identify the frequency content of each candidate bowel sound event and characterize it as bowel sound or artefact [2]. In this context, the output of this process is a bowel sound mask signal per channel with non-zero values that correspond to the positions of bowel sound events. Finally, three GI mobility indices are calculated, i.e., BS per minute (BSPM), sound-to-sound interval (SSI) and mean BS duration (BSD). The above analysis pipeline was evaluated on a dataset consisting of BS recordings from 7 adult subjects during an STT, along with expert-based BS annotations as the ground truth. The performance is evaluated via the measures of the true positive rate (TPR) and sensitivity. In overall, the TPR is 40-80%, implying that in many cases there are a lot of false positive events, whereas the highest TPR of each subject, produced by a single channel, ranges between 60-80%. The relatively high number of false positives may be caused by the way the expert evaluated the abdominal sound recordings, i.e., by listening to a single three-channel audio file rather than three separate single audio files. In this way, the expert may have missed or misinterpreted bowel sounds that appear on a single channel and are suppressed by the superposition of the other two. Sensitivity, in overall, ranges from 50% to 98% while the best performance by a single channel for each subject is higher than 70% in most cases. The results of the motility indices calculation validate the expected behaviour, i.e., BSPM increase and SSI decrease during the SST. However, this was not the case for BSD that slightly decreased instead of the op | poster |
Implications of the mid-IR for ALMA flare observations Hugh Hudson1,2, Sam Krucker2,3, Matt Penn4, and Paulo Simões1 1U. of Glasgow, UK; 2UC Berkeley, USA; 3FHNWS, Windisch, Switzerland; 4NSO Tucson, AZ USA Synopsis: Mid-IR observations (the 10µ band) of solar flares have now become possible (Kaufmann et al. 2015; Trottet et al. 2015; Penn et al. 2016). This poster reviews the new data in the ALMA context. Right: Schematic global spectra of a solar flare as it appeared to Ohki & Hudson (1975), for the impulsive phase (;eft) and the gradual phase (right) of a solar flare. The new IR observations: Several flares have now been observed in the 10µ band (Kaufmann et al. 2015). The most detailed results come from observations at the McMath-Pierce telescope of SOL2014-09-24 (Penn et al. 2016). Figures 1-4 (map, timeseries, overlays, spectrum) show these observations, made with independent QWIP array detectors in broad passbands at 5.2 µm and 8.2 µm. Above: There really is a gap in our observational parameter space, being fiilled in now via ground-based IR observations from above, and ALMA from below. pre-flare (5 μm) pre-flare (8 μm) flare peak (5 μm) flare peak (8 μm) 10 100 1000 frequency [THz] 102 103 104 105 differential radiative energy flux [sfu] 100 x hot coronal free-free pre-flare black body from IR source 10 1 wavelength [micron] 8.6 micron: 24-Sep-2014 17:49:24.483 -385 -380 -375 -370 -365 -360 -355 X (arcsecs) -330 -325 -320 -315 -310 -305 Y (arcsecs) 20-100 keV 8.6 micron HMI 617 nm: 24-Sep-2014 17:49:18.900 -385 -380 -375 -370 -365 -360 -355 X (arcsecs) -330 -325 -320 -315 -310 -305 Y (arcsecs) 20-100 keV 617 nm AIA 94 A: 24-Sep-2014 17:49:13.120 -385 -380 -375 -370 -365 -360 -355 X (arcsecs) -330 -325 -320 -315 -310 -305 Y (arcsecs) 20-100 keV 94 A Fig. 1: Peflare (upper) and flare (lower) images in the two mid-IR passbands. Note the well-resolved sunspots and faculae, and the excellent signal-to-noise ratio for the flare emissions. The flare footpoint sources are not resolved spatially. Fig. 2: Light curves of the two mid- IR bands and hard X-rays observed by RHESSI. The background gray figure shows GOES 1-8Å. The IR time variability is not well resolved at 1 s. Fig. 3: Images at 8.2µ, HMI white light, and AIA 94Å, overlaid with RHESSI hard X-ray contours. Fig. 4: Spectrum at the peak of the flare, combining the two mid-IR points with the HMI observation in “white light.” The infrared spectrum matches that expected from optically-thin thermal bremsstrahlung. Significance: The excellent signal-to-noise ratio in the observations of SOL2014-09-24 leads to great optimism about future observations, since it was a minor event (GOES class C7.4). We were surprised to see the clear identification of the mid-IR sources with the impulsive-phase signatures in the deep atmosphere. These data therefore will contribute enormously to our knowledge of the main flare energy release. Other new IR observations: The observations described above add to the remarkable progress of the group of Pierre Kaufmann (São Paulo) in several directions, including the observation of several other flares at 30 THz (the 10µ band). They have also successfully observed solar flares in the “sub- THz” range at 212 GHz and 405 GHz. These systematic observations come from a dedicated facility at the El Leoncito site in the Andes. Most recently, this group has recently completed a successful balloon flight pioneering solar observations in the far IR at 3 THz and 7 THz. All of this contributes to filling in the great spectral gap that has heretofore existed. Implications for ALMA: Between the new mid- and far-IR observations now appearing, and the forthcoming ALMA flare observations, we will be able to characterize the flaring atmosphere directly, using the easy-to-characterize continuum rather than having to rely on the complexities of radiative transfer in spectral lines. The figure below (Wedemeyer et al. 2016) shows quiet-Sun contribution functions for the A | poster |
MetaSearch: Phenotypic Search across public MRI data Satrajit Ghosh1, B. Nolan Nichols2, Katja Heuer3, Amy Robinson Sterling4, Roberto Toro5 1Massachusetts Institute of Technology, Cambridge, MA, 2Genentech, Menlo Park, CA, 3Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 4Princeton University, Princeton, NJ, 5Institut Pasteur, Paris, France Acknowledgements We acknowledge all who have made data available publicly and the support of Phase I funds for the Open Science Prize challenge. References [1] http://openneu.ro/ [2] https://github.com/OpenNeuroLab/metasearch [3] https://zenodo.org/ [4] https://osf.io/ Introduction Growing number of human brain imaging datasets shared online that have related metadata, such as disease diagnostics, age, sex and other phenotypic, demographic or imaging information. The 1000 Functional Connectomes Project (FCP) and International Neuroimaging Data-sharing Initiative (INDI) are great examples of openly available brain imaging datasets with corresponding metadata. However, these data have diverse directory structures and file formats that make cross-dataset queries a time intensive project. With MetaSearch, we propose a Web platform that allows finding resources, filtering information by a user's needs, and enables social, distributed curation of scientific data. It is provided by the Open Neuroimaging Laboratory as a companion to BrainBox, a brain MRI curation and annotation tool. Methods MetaSearch provides an integrated view of projects organized under the FCP efforts, but also data from Open Science Framework, Zenodo, Dropbox and others. It accomplishes this by extracting metadata for these projects from the AWS cloud, transforming it into a common data model, and then loading the integrated dataset into the MetaSearch app. MetaSearch uses an implementation of parallel coordinate charts written in D3.js that allows for selecting subsets of multidimensional datasets that are also rendered in a tabular format using SlickGrid. By using this app you can perform queries visually to select a cohort of participants with brain imaging data based on their demographics and phenotypic information and then link out to imaging measures. Using GitHub, we provide a common platform for other developers to contribute additional datasets to the search engine. Faceted search Brainbox Integration Map your data | poster |
Introduction Method Results Results Discussion Future Prospects Abstract Stuart Hall's communication model shows that media and other cultural contexts are molded by dominant discourses and power systems. Hence, this study uses Hall's model to analyze viral and harmful media stereotypes, their toxic effects on individuals and society, and media's role in shaping cultural perceptions. This study examines three levels of stereotypes— masculine power, gender stereotypes and social stigmas. Evidence synthesis is employed to evaluate several studies on damaging media stereotypes that match with Hall's postulations to extract and frame these biases for critical discourses. This study adds to the body of research on media representations by revealing how media stereotypes impair historical, cultural, and sexual identities. In the field of media and cultural studies, Stuart Hall’s (1973) communication model provides a useful framework for analyzing the interplay between discourse, power structures, and media. *Figure 2. Circle size is related to the number of studies mentioning the word. Circle color is related to the stereotype category. The lines connecting the nodes indicate semantic relationships or associations. The network reveals clusters of related terms. The semantic variability of this text network analysis is focused because it centers around specific themes and interconnected terms Text Network Analysis showing nodes extracted from titles, abstracts and/or Intros of the 61 studies Semantic Variability Scale of Nodes *Figure 5 . The United States made a complete contribution to all the selected research, accounting for 100% (61). These studies were sourced from 18 different states within the country. The research institutions in the Northeast region of the country accounted for 56% of the selected studies. New York State provided 33% of the entire papers, closely followed by California State in the Southwest, which accounted for 20%. Spatial Analysis showing the %-distribution of the selected studies (n = 61) within the US L - R The current analysis incorporates a range of trends shown in reviewed studies. The first chart shows 63% of respondents saying that the different forms of stereotypes are either perpetuated or reinforced by the media. The second chart shows 57% of respondents admit that the media perpetuates and reinforces human- related stereotypes by selectively covering specific pieces of information rather than the entirety. According to the third chart, most respondents (58%) believe that television is the primary medium through which media-driven stereotypes are spread (for example, in the form of films or broadcasts from news outlets.) Media in all its forms has long shaped society's values, norms, and beliefs (Tankard & Paluck, 2016). The fact that media signals are encoded with unique meanings by content providers is an endorsement of Hall's communication model. According to Hall (2000), these interpretations are impacted by many social, cultural, and political factors. Castleberry (2016) argues that ideological frameworks frequently impact the media's ability to encode messages that become stereotypes by giving more weight to some narratives and viewpoints and less weight to others. Take gender stereotypes as an example. Media portrayals frequently uphold damaging and restricting perceptions of masculinity and femininity by adhering to established gender norms and roles. Women are typically shown as nurturing figures or romantic interests, whereas males are typically portrayed as strong and dominating. These stereotypes normalize and legitimize uneven gender interactions, which in turn helps to perpetuate preexisting power systems. Bødker (2018) notes that audiences have a crucial role in understanding media messages and creating meaning by drawing on their personal experiences, beliefs, and cultural backgrounds, as emphasized by Hall's model. On the other hand, viewers may infer stereotypes from media por | poster |
ZeroPM - Policy The main objective of WP3-Policy is to stimulate and support policy changes to more effectively tackle persistent and mobile substances through regulatory measures. With this approach WP3 feeds into the “prevention”-objective of the toxic- free hierarchy. This will be achieved through the following sub-objectives: ▼To describe relevant European and international policy objectives and actions as well as needs and challenges for realising them. ▼To analyse opportunities and gaps in existing policy frameworks for preventing persistent and mobile substances from entering the environment. ▼To develop policy actions tailored to groups of persistent and mobile substances, uses or sectors and assess their impacts on different actors and sectors as well as their feasibility of facilitating a transition towards zero pollution from persistent and mobile substances (with WP4 Market transition) ▼To design roadmaps for groups of persistent and mobile substances, uses or sectors as well as to develop and disseminate concise policy messages by engaging with all relevant stakeholders throughout the project. Hans Peter Arp Deputy Coordinator hans.peter.arp@ngi.no Norwegian Geotechnical Institute & Norwegian University of Science and Technology Alicia McNeill Associate Advisor Alicia.McNeill@milieu.be Milieu Law & Policy Consulting Jona Schulze Associate Advisor Jona Schulze@uba.de German Environment Agency (UBA) Introduction ▼Analysis of the EU-level zero-pollution policy ambitions: actions, needs and challenges with respect to selected persistent and mobile substances ▼Suggested policy actions and roadmaps for meeting the zero-pollution ambitions ▼Policy briefs presenting key findings and recommendations for policy actions for meeting the zero-pollution ambitions Results ▼‘Regulatory watch’ to identify opportunities to feed findings into the EU regulatory process, e.g., upcoming reviews of the Urban Wastewater Treatment Directive, the Sewage Sludge Directive, and other relevant regulatory frameworks including REACH, CLP, and product legislation ▼Analysis of survey data and stakeholder feedback for new and recent legislative initiatives, including the Chemicals Strategy for Sustainability ▼Mapping of existing EU regulatory frameworks on chemicals including substances used in specific products as well as water, waste and soil policy ▼Development and assessment of policy options Example tasks Acknowledgements Mariya Gancheva, Melanie Muro, Tugce Tugran, Lucille Labayle, Milieu Law & Policy Consulting Alexander Badry, Tobias Mohr, UBA This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101036756. Sarah Hale Project Coordinator sarah.hale@ngi.no Norwegian Geotechnical Institute Partners Ivo Schliebner Advisor Ivo.Schliebner@uba.de German Environment Agency (UBA) Michael Neumann Advisor Michael.Neumann@uba.de German Environment Agency (UBA) Gretta Goldenman Advisor G.Goldenman@milieu.be Milieu Law & Policy Consulting Lise Oules WP3 leader Lise.Oules@mileu.be Milieu Law & Policy Consulting The first PMT/vPvM substances to be listed as SVHCs or to be proposed for restrictions under REACH zeropm.eu ▼Stakeholder interviews and workshops to explore the feasibility of policy measures ▼Synthesis and development of policy messages HFPO-DA (GenX) 1,4-dioxane PFHexA PFBS | poster |
The Effects of Ocean Acidification on the Metabolic Rate and Swimming Performance of Bonefish (Albula vulpes) Jake Valente, Makayla Barton, Kearney McDonnell, Sean McGurl, Olivia Millspaugh, Mickey Mittermeier, and Rennie Meyers Advisors: Aaron Shultz and Kit Hayward Methods Bonefish were collected with a seine net from Starved Creek in the spring of 2010, in Southern Eleuthera. They were transported back to the Cape Eleuthera Institute wet laboratory, where they were transferred to holding tanks. Bonefish remained in the holding tanks for a minimum of 48 hours before being transferred to their acclimation tanks. Tank pH was adjusted over a 24-hour period to predicted ocean acidification levels in 100 years made by the Intergovernmental Panel on Climate Change. The pH levels in the acclamation tanks were 7.8, 7.6, and 7.4. The bonefish were acclimated for a minimum of 7 days to the following pH treatment: 7.8, 7.6, and 7.4. Fish were not fed 48 hours prior to testing. The volume and weight of each fish was recorded before they were loaded into respirometry chambers, and this process is exemplified in figure 2. AutoResp4 software recorded oxygen consumption overnight during alternating recirculation and flush periods (Figure 3). During the recirculation period, water flows past a dissolved oxygen probe in a closed system. The six lowest oxygen consumption values collected during the recirculation period with r² >0.95 were averaged. Water from the surrounding tank is pumped through the chamber during the flush period in order to refresh the water. The following day, fish were transferred to a saltwater pool, with 3 parallel lines each 37 cm apart, and were exercised by pinching their caudal fins. The number of times a fish crossed a line and time until exhaustion was recorded. Fish were considered exhausted when they did not burst swim after 2 consecutive caudal pinches. Total and fork length of the bonefish was recorded, after which fish were recovered and released. Introduction Global Climate Change can be defined as any change in climate over time. Before the Industrial Revolution, CO2 concentrations were at a value of 280 parts per million (ppm), driving that level up to 385 ppm in 2008. Temperatures are rising at the fastest rate they ever have in the past 1,000 years. Coastal flats are classified as shallow marine environments including tidal creeks, lagoons and mangrove swamps. These environments are vital to the entire marine ecosystem because of their roles as nurseries for juvenile reef fish. Ocean acidity resulting from increased CO2 in the atmosphere may have negative impacts on fish. The average pH of the oceans has dropped by 0.1 and there has been a 30% increase in hydrogen ion concentration. When fish ventilate their gills, these ions diffuse through their gills and into their blood stream, creating and imbalance in their acid-base chemistry. This may increase the stress levels of fish, causing them to consume more oxygen, which in turn makes it difficult for the fish to carry out life processes. A species of fish that may be affected by these three factors is the bonefish. Bonefish also play a key role in local economies of the Bahamian Archipelago. Because of their strength and difficulty to catch, anglers travel to the Bahamas for recreational fishing. The purpose of this study was to test the effects of global climate change caused by anthropogenically produced CO2 on Bonefish. The test will measure both the oxygen consumption and the swimming performance of bonefish when they are exposed to incremental decreases in pH, which are the values predicted by the IPCC for the next 100 years. It was hypothesized that as pH decreased the swimming performance of Bonefish would decrease while their metabolic rate increased. Literature Cited Brierly, Andrew S and Kingsford, Micheal J. 2009. “Impacts of Climate Change on Marine Organisms and Ecosystems.” Current Biology. 19: 602-614. A.J. Danylchuk, S.E. Danylchuk, S.J. | poster |
Elevation Control on Vegetation Organization in a Semiarid Ecosystem in Central New Mexico Sai Siddhartha Nudurupati1, Erkan Istanbulluoglu1, Jordan M. Adams2, Daniel Hobley3, Nicole M. Gasparini2, Gregory E. Tucker3 and Eric W. H. Hutton4 1 Department of Civil and Environmental Engineering, University of Washington, Seattle, WA, USA 2 Department of Earth and Environmental Sciences, Tulane University, New Orleans, LA, USA 3 CIRES and Department of Geological Sciences, University of Colorado, Boulder, CO, USA 4 Community Surface Dynamics Modeling System (CSDMS), University of Colorado, CO, USA INTRODUCTION Semiarid and desert ecosystems are characterized by patchy and dynamic vegetation Topography has been observed to play a commanding role on vegetation patterns In this study, we investigate the role of elevation dependent climatology on vegetation organization in a semiarid catchment in New Mexico, USA We develop a ecohydrologic cellular automaton model within Landlab, a component based modeling framework for earth surface (http://landlab.readthedocs.org). The model couples local vegetation dynamics model with cellular automata plant establishment and mortality model based on Zhou et al. (2013). The model is driven by elevation dependent rainfall, temperature and radiation Model results reproduce elevation and aspect controls on observed vegetation patterns LANDLAB: ECOHYDROLOGY VEGETATION ORGANIZATION: ASPECT VEGETATION ORGANIZATION: ELEVATION MODELING ELEVATION DEPENDENCEKnow More About The Landlab here: http://Landlab.github.ioContact: saisiddu@uw.edu & erkani@u.washington.edu Landlab Ecohydrology Components: Storm Generator: generates rectangular Poisson distributed storms Radiation: calculates daily spatially distributed solar radiation (Radiation Factor) Potential Evapotranspiration (PET): uses solar radiation fields and weather variables to calculate PET at each model element Soil Moisture: solves root zone water balance between two storms given PET and rainfall fields ; returns actual evapotranspiration and soil moisture at inter storm durations Vegetation: computes net primary productivity based on actual evapotranspiration and calculates leaf area index and biomass Cellular Automata Competition: models competition by keeping track of probabilistically calculated mortality and establishment of plants driven by water stress and plant age Fig. 1: Point Model Validation of Leaf Area Index at Nebraska Sand Hills Fig. 2: Simulation on flat topography Fig. 3: Simulation on actual topography in Sevilleta, Central New Mexico Fig. 5: Observed elevation dependent land cover in a catchment in central New Mexico Fig. 4: Elevation dependence on Potential Evapotranspiration and Precipitation [1]References: 1. Caylor, Kelly K., Salvatore Manfreda, and Ignacio Rodriguez-Iturbe. "On the coupled geomorphological and ecohydrologicalorganization of river basins." Advances in Water Resources 28.1 (2005): 69-86.2. Zhou, Xiaochi, Erkan Istanbulluoglu, and Enrique R. Vivoni. "Modeling the ecohydrologicalrole of aspect‐controlled radiation on tree‐grass‐shrub coexistence in a semiarid climate." Water Resources Research 49, no. 5 (2013): 2872-2895. CONCLUSIONS To increase computational efficiency ecohydro- logically similar grids are developed into bins for soil moisture and water stress simulations. 10 slope bins X 12 aspect bins X 5 elevation bins X 4 vegetation type bins are used. Water stress is mapped from representative grid to actual (topography) grid annually. CA plant competition is driven by water stress Sample Area for Analysis PET & Precip Gradient: Year 2000 Precip Gradient: Year 2000 PET Gradient: Year 2000 Landlab Driver for this Analysis Fig. 6: Modeled elevation dependent vegetation organization in a catchment in central New Mexico This study demonstrates a preliminary evaluation of Landlab: Ecohydrology in Central New Mexico. The model shows general agreement with observed aspect-dependent and elevation-dependent | poster |
Transferencia de energía en NP de polímeros conjugados: modelado y contraste con datos experimentales. Rodrigo A. Ponzio1.2.*, Franco N. Bellomo1.†, Lucas E. Bellomo1.‡, Daniel A. Bellomo3, Rodrigo E. Palacios2 1. Dpto. de Física, FCEFQyN, UNRC 2. Dpto. de Química, FCEFQyN, UNRC 3. UTI, UNRC *rponzio@exa.unrc.edu.ar †fnbellomo@protonmail.com ‡lbellomo@protonmail.com 1. Introducción 3. Propiedades de la NP 4. Eficiencia de Desactivación Agradecimientos y Ref. • A la organización de la Escuela Giambiagi por otorgarnos las ayudas económicas. • Rodrigo A. Ponzio posee una beca interna doctoral de CONICET. • Rodrigo E. Palacios es miembro de la carrera de investigador científico (CIC) del CONICET. • Este trabajo fue financiado por: ANPCyT (PRH23 PICT 140/08, PME), ANPCyT-CONICyT (PICT 2691/11), SECyT UNRC (PPI/10) MINCyT Córdoba (PID 033/2010) • Al Unidad de Tecnología de la Información (UTI) UNRC y al Centro de Cómputos de Alto Rendimiento - CONICET Rosario. • Al Dr. Federico Agazzi. 2. Algoritmo de generación de puntos en una esfera Fig. 2 Puntos distribuidos en la superficie. Siendo R el radio de la NP y U una variable aleatoria (v.a.) uniforme en (0, 1) para la generación volumétrica o 1 para el caso superficial. X1, X2, X3 son v.a.i. normales. Fig. 1 Puntos distribuidos en todo el volumen. 3. Modelado de Transferencia de Energía • Los resultados de las simulaciones reproducen satisfactoriamente los resultados experimentales utilizando valores de y iguales para tres sistemas con distintos dopantes. • Se contrastará con datos experimentales simulaciones de NPs dopadas superficialmente. El grupo de Fotoquímica de la UNRC posee experiencia en la síntesis de NPs dopadas superficialmente y ya se dispone de los resultados experimentales necesarios para realizar esta comparación con la simulación. • Se ampliará el algoritmo de TEN para tener en cuenta la distribución real de tamaños de NP, y no sólo su tamaño medio. Dicha distribución ya ha sido medida por nuestro grupo utilizando un Microscopio de Fuerza Atómica. 6. Conclusiones y Proyecciones 5.Resultados 1- Se generan X dopantes en la NP, donde X viene dado por la densidad de dopaje de la NP. El excitón se genera con la misma probabilidad en cualquier punto de la NP debido a que la longitud de penetración de la luz de excitación es mucho más grande que el diámetro de la NP, por lo que la intensidad del haz de luz se puede asumir constante en todo su volumen (Fig. 3). 2- Se calcula la probabilidad de transferencia del excitón a cualquier dopante (Eq. 2) asumiendo un mecanismo de TE de tipo Förster (Eq. 3) que depende de la distancia a cada uno de estos (Fig. 4) de la forma: Fig. 3 Generación de dopantes y excitón en la NP Los polímeros conjugados son macromoléculas compuestas por monómeros que presentan enlaces simples y múltiples alternados. Dentro de la cadena existen segmentos (cromóforos) de longitud variable en donde los electrones π se encuentran deslocalizados. Debido a la heterogeneidad estructural de estos materiales, los procesos de transferencia de energía (TE) entre cromóforos y dopantes son altamente complejos. El mejor entendimiento de estos procesos es de importancia para el desarrollo de dispositivos orgánicos-electrónicos1. En este trabajo se presentan simulaciones de Monte Carlo realizadas con TEN (Trasnferencia de Energía en NanoParticulas) y su validación con datos experimentales2. TEN es sofware libre disponible en github3 implementado en python, desarollado por el Laboratorio de Microscopia Óptica Avanzada de la UNRC. Las librerías utilizadas son Numpy4, Matplotlib5 y MPI4py6, con este última paralelizandolo para poder correr en el cluster. Poster Nº24 Fig. 4 Distancia del excitón a los dopantes. Fig. 5 Paso aleatorio del excitón. 3- Se generan números aleatorios que se comparan con las probabilidades de los dos procesos para determinar si el excitón ha experimentado un decaimiento o se a transferido a un dopante, terminando la trayectoria. De no ser así, el ex | poster |
Customized workflow development and data integration concepts in Systems Medicine Markus Wolfien markus.wolfien@uni-rostock.de Gustav Steinhoff gustav.steinhoff@med.uni-rostock.de Olaf Wolkenhauer olaf.wolkenhauer@uni-rostock.de www.sbi.uni-rostock.de References [1] Lott SC, Wolfien M, Riege K, Bagnacani A, Wolkenhauer O, Hoffmann S, Hess WR. Customized workflow development and data modularization concepts for RNA-Sequencing and metatranscriptome experiments. Journal of Biotechnology. 2017 doi.org/10.1016/j.jbiotec.2017.06.1203 [2] Wolfien M, Rimmbach R, Schmitz U, Jung JJ, Krebs S, Steinhoff G, David R, Wolkenhauer O. TRAPLINE: A standardized and automated pipeline for RNA sequencing data analysis, evaluation and annotation. BMC Bioinformatics. 2016. doi: 10.1186/s12859-015-0873-9. [3] Steinhoff G, Nesteruk J, Wolfien M, Kundt G, The PERFECT Trial Investigators. Cardiac Function Improvement and Bone Marrow Response Outcome Analysis of the Randomized Perfect Phase III Clinical Trial of Intramyocardial CD133 + Application After Myocardial Infarction. EBioMedicine. 2017. doi.org/10.1016/j.ebiom.2017.07.022 Workflows: Symbiosis of research and tool integration for clinical application What is TRAPLINE? bit.ly/TRAPLINE_RNAseq 0 Integrating data using a Systems Medicine approach Systems Biology Data integration (DisGeNet, miRCancer, TriplexRNA, …) ATCATG101000111 TAGTG101010101111 TTCATAA00011011 AAGCA1010011 Statistics Evaluation of omics data (RPKM, FDR, Bayes, …) Bioinformatics Automated and scalable data processing, e.g. TRAPLINE [2] Med. Informatics Data management Clinic Improved diagnosis, prognosis and therapy Unexplained symptoms New insights mRNA1 miRNA1 mRNA2 miRNA2 mRNA3 Up regulated Down regulated Disease associated GO term 101000111ATCATG 101010101111TTCATAA 00011011AAGCA 1010011TAGTG 0 -10 10 log2(fold change) significant yes no 0 1 2 3 4 -log10(p value) Disease Biomarkers miRNA 2 mRNA 1 miRNA 1 mRNA 2 mRNA 3 Machine learning Data classification and prediction Application of the integrative workflow: The Phase III clinical trial PERFECT Workflow management frameworks and cloud computing services are bridging the gap between tool developers and end users, aiming towards an easy applicable and up-scalable computational data analysis. This in turn allows for an improved data reproducibility, process documentation, and monitoring of submitted jobs. Finally, workflows facilitate the use of state-of-the-art computational tools which would be hard to access for non-experts without graphical user interface frameworks. However, the use of workflows could be even more simplified for experimental and clinical researchers by strengthening the specific focus on the addressed research hypothesis and lessening the effort for the selection of the most appropriate tool [1]. Regenerative therapies using stem cells for the repair of heart tissue have been at the forefront of preclinical and clinical development during the past 16 years. To build upon this progress, the Phase III clinical trial PERFECT was designed to assess clinical safety and efficacy of intramyocardial CD133+ bone marrow stem cell treatment combined with coronary artery bypass graft (CABG) for induction of cardiac repair. The primary endpoint was delta left ventricular ejection fraction (∆LVEF) at 180 days compared to baseline measured with magnet resonance imaging (MRI). Responders (R) classified by ∆LVEF ≥5% after 180 d were 60% of the patients (35/58) in both treatment groups (+17.1% in R vs. non-responders (NR). The PERFECT trial shows that cardiac tissue repair and restitution of left ventricular function can be successfully installed in ischemic heart disease by CABG surgery associated with presence of enhanced circulating CD133+ and CD34+ EPC level. Using this new computer-aided diagnostic technology, responsive patient characteristics can be accurately identified prior to treatment with bypass surgery and stem cells [3]. Outcome results of the PERFECT trial. | poster |
Research goals The main goal will be a detailed analysis of the communication between Emperor Sigismund of Luxembourg and Nuremberg based on diplomatic materials. It will provide a diplomatic analysis of Sigismund‘s charters for Nuremberg combined with the question of how Nuremberg used its contacts to the emperor's court to win the ruler's favor. Combining the approaches from political communication and diplomatics with digital humanities, the project aims to discuss “new uses for an old science” (Duranti). Diplomatic analysis Includes the classic approach of studying the analytic dimension of charters (style, forms, chancery notes, etc.) and the genetic dimension, focusing on the phases of creation of the charters and persons involved. Digital Humanities Application of computer-based methods (primarily HTC and NLP) on an enhanced source corpus (including charters for burghers, Jews, burggrave of Nuremberg, etc.) for a comparison of the diplomatic material About this project Previous research verified close diplomatic and financial ties between Nuremberg and emperor Sigismund of Luxembourg. However, a study on political communication between both remains a desideratum. The many privileges issued by Sigismund for promise a valuable insight into the relationship between the emperor and one of his closest allies. They form the main subject of the following research- project, for which we applied to the Czech Science Foundation (GAČR) for three-year funding. The Communication between Sigismund of Luxembourg and the imperial city of Nuremberg Project Schedule 2025 Joint-organizing of a section at the Summer School Scriptorium Brunense in Brno focusing on Digital Humanities (summer) and an international Workshop on royal and imperial diplomatics concerning medieval towns (autumn/winter) 2026 Publication of two case studies 2027 Completion of a monograph by Stanislav Bárta and Tobias Heil Project details Project leader: Stanislav Bárta, PhD. (Brno) Co-researcher: Tobias Heil (Brno) Collaberative Partners: Regesta Imperii Branch Office Brno / Vienna States archive Nürnberg Dr. Daniel Luger (Graz, DiDip) as consultant Duration: 2025 – 2028 Funding (planned): Czech Science Foundation (GAČR) Contact: Tobias.Heil@mail.muni.cz Political communication Involves the reconstruction of the council’s network of contacts at the royal court and chancery with the help of accounting books and correspondence. This sheds light on the council’s active role during negotiations of privileges. Picture credits: Hidden Cat, miniature from Conrad of Megenberg, ‘Das Buch der Natur’, Germany ca. 1434. Strasbourg, Bibliothèque nationale et universitaire, Ms.2.264, fol. 85r (https://www.openculture.com/2022/10/cats-in- medieval-manuscripts-paintings.html); Sigismund of Luxembourg, miniature from Eberhard Windeck: Das Buch von Kaiser Sigismund, folio 212r (commons.wikimedia.org); Emperor Sigismunds charter for the city of Nuremberg (1433, May 31), StA Nürnberg, LosungA, Kaiserprivilegien, Nr. 337 (Digitalisat, Staatsarchiv Nürnberg); Nürnberg: miniature from Braun, Georg; Hogenberg, Franz; Novellanus, Simon: Beschreibung vnd Contrafactur der vornembster Stät der Welt, 1572, Köln 1582 (Digitalisat der Universitätsbibliothek Heidelberg) Tobias Heil, MA Institut of Auxilary Historical Science, and Archival Studies, Masaryk University, Brno Poster-presentation at the Summer School “Computational Language Technologies for Medievalists” Graz 8th – 12th of July 2024) | poster |
. . . . DasLabelingSystem–einfreierBaukasten fürkontrollierteVokabulare Michael Piotrowski, Florian Thiery, Kai-Christian Bruhn . . Problem . • Maschinenlesbare Annotationen sind Voraussetzung für semantische Verarbeitung von Daten. • Kontrollierte Vokabulare sind notwendig, um Annotationen maschinell verarbeitbar zu machen. • Kontrollierte Vokabulare abstrahieren von natürlichsprachlichen Ambiguitäten und Konnotationen: entscheidend für die semantische Verarbeitung von Forschungsdaten. • Für projektübergreifende Zusammenarbeit und semantischen Datenaustausch müssen Vokabulare nicht nur kontrolliert, sondern auch formell oder informell standardisiert sein. • Standardisierte kontrollierte Vokabulare ermöglichen Austausch, Kombination und gemeinsame Analyse annotierter Daten aus verschiedenen Quellen sowie Implementierung generischer Werkzeuge. • Erstellung und Wartung standardisierter kontrollierter Vokabulare sind jedoch teuer. • Alle beteiligten Parteien müssen zu gemeinsamem Verständnis der Begriffe kommen und Balance zwischen möglichst breiter Anwendbarkeit und möglichst präziser Analyse andereseits finden. • Ziele insbesondere in den Geisteswissenschaften schwierig zu erreichen: Potentielle Forschungsfragen extrem weit gefächert, Kategorisierung der Daten ist häufig ein essenzieller Teil des Forschungsprozesses selbst. ➜Eklatanter Mangel an standardisierten kontrollierten Vokabularen in den Geisteswissenschaften. Digital-Humanities-Projekte sind gezwungen, eigene, projektspezifische Vokabulare zu definieren. Projektspezifische Vokabulare können internen Bedarf kurzfristig befriedigen, sind aber nicht interoperabel und verhindern zukünftigen Austausch und Nachnutzung annotierter Daten. . . Ansatz . Concept Concept Concept Concept Concept Concept Term Label Label ... Vocabulary Reference thesaurus Da es in der geisteswissenschaftlichen Forschung praktisch unmöglich ist, kontrollierte Vokabulare zu definieren, die alle denkbaren Anwendungen abdecken und generell akzeptiert sind, schlagen wir ein anderes Vorgehen vor. Bei unserem Ansatz definieren Projekte ihre eigenen Vokabulare, aber anstelle natürlichsprachlicher Definitionen werden die Terme mit einem oder mehreren Konzepten in einem Referenzthesaurus verknüpft. Der projektspezifische Term dient also quasi als »Label« für eine Menge gemeinsamer Konzepte. Dieser Ansatz ermöglicht es Projekten, Vokabulare entsprechend ihrer Bedürfnisse und unter Verwendung der im jeweiligen Forschungsgebiet üblichen Bezeichnun- gen benutzen, während gleichzeitig die Interoperabilität mit anderen Projekten über den Referenzthesaurus gewährleistet ist. . . Implementierung: Das Labeling System . Webanwendung, die es Benutzern ermög- licht, SKOS-Vokabulare zu erstellen und auf einfache Weise deren Terme mit einem oder mehreren Konzepten in einem oder mehreren Referenzthesauri zu verknüp- fen (broadMatch, narrowMatch, close- Match, exactMatch, relatedMatch, see- Also, sameAs und isDefinedBy). Die Benutzeroberfläche ermöglicht die Vi- sualisierung der definierten Vokabulare in einer Baumstruktur. Mit der CSV-Upload- Funktion kann ein CSV-Dokument hochge- laden werden, das mehrere prefLabels, altLabels, notes und definitions ei- nes Labels enthält und zudem Relatio- nen broader/narrower/related inner- halb von Vokabularen sowie die Links zu externen Ressourcen beschreibt. Externer Zugriff auf Vokabulare über SPARQL-Schnittstelle. Das Labeling System basiert auf ausgereif- ten Open-Source-Komponenten und ist selbst ebenfalls frei verfügbar. place types winery monastery inn church http://vocab.getty.edu/aat/300056005 - worship http://vocab.getty.edu/aat/300379053 – meal http://vocab.getty.edu/aat/300379053 – meal http://vocab.getty.edu/aat/300265204 – wine making http://vocab.getty.edu/aat/300056005 – worship http://vocab.getty.edu/aat/300265204 – wine making . . Institut für Raumbezogene Informations- und Messtechnik Hochschule Mainz University of Applied Sciences http://labeling.i3mainz.hs-mainz.de/ Michael P | poster |
Heavy neutral lepton (HNL) Heavy neutral lepton (HNL) production searches at NA62 production searches at NA62 XXVIII International Conference on Neutrino Physics and Astrophysics, Heidelberg, June 2018 Lorenza Iacobuzio, University of Birmingham - lorenza.iacobuzio@cern.ch Neutrino Minimal Standard Model Previous measurements HNL production searches at NA62 Event selection Data-MonteCarlo comparison SM extension accounting for baryon asymmetry of universe (BAU), dark matter (DM), neutrino masses and oscillations 3 additional right-handed, singlet, Majorana HNLs (not observed yet) N1 mass O(10 keV/c2), good DM candidate N2,3 mass O(1 GeV/c) [2] B(K+ → l+N) depends on BSM(K+ → l+ν), HNL-lepton coupling U 2 l4, and kinematic factor [2] Fixed-target experiment at CERN SPS: SPS 400 GeV/c p beam onto Be target → 75 GeV/c K+ In-flight K+ decays in 60 m long fiducial volume (FV) Data taking (2015-2018) with possibility to extend beyond 2021 Measure B(K+ → π+νν) with 20% precision to study CKM matrix element Vtd Perform hidden sector searches in presence of K+ beam (axions, dark photons, HNLs) Minimum bias run (2015) [1]: Data collected during 1.2·104 SPS spills (about 3 s effective spill) 0.4% - 1.3% of nominal beam intensity (3.3·1012 protons on target per spill) HNL production searches in kaon decays [1]: Kaons tagged with upstream Cherenkov detector (70 ps time resolution) Lepton tracks reconstructed in downstream spectrometer (130 μm spatial resolution) Particle ID with downstream Cherenkov detector, spectrometer and calorimeters One positive track with momentum in (5, 70) GeV/c, in time with kaon No extra activity in photon veto systems Positrons and muons identified through energy-momentum ratio [1] Squared missing mass: m2 miss = (PK - Pl)2 (SM K+ → l+ν peak at m2 miss = 0) HNL signal regions: 170 < mmiss < 448 MeV/c2 for K+ → e+N and 250 < mmiss < 373 MeV/c2 for K+ → μ+N [1] [2] JHEP0710:015 (2007) [3] Physical Review D 91, 052001 (2015) [4] Physical Review Letters 49, 18 (1982) [5] Physics Letters B 772, 712–718 (2017) ν M S M p a r t i c l e z o o l o g y NA62 schematic layout. HNL signal topology is visible ● PMNS mixing matrix between ● HNL flavour and mass eigenstates ● Expected and observed UL (at 90% CL) from NA62 2007 data-taking [4] Production searches: Look for peaks in missing mass distribution Decay-model independent Sensitive to long-lived HNLs Previous measurements in K + → μ+N 90% CL upper limits (UL) on HNL-muon coupling U 2 μ: KEK E089 (1982) [3]: (10 6 −, 10 4 −) for mN in (70, 300) MeV/c2 BNL E949 (2015) [4]: (10 9 −, 10 7 −) for mN in (175, 300) MeV/c2 NA62 (2017) [5]: (2·10 6 −, 10 5 −) for mN in (300, 375) MeV/c2 ● Expected and observed number of events: K+ → e+N (left) and K+ → μ+N (right) [2] ● Squared missing mass distributions for data and simulated events passing the e+ (left) and μ+ (right) selections [2] Technique, results and future prospects ● Squared missing mass distributions for data and simulated events passing the e+ (left) and μ+ (right) selections [2] Mass scans performed in HNL signal regions with step size of 1 MeV/c2 For each HNL mass hypothesis, background evaluated from sidebands of data mmiss distribution No statistically significant HNL production signal observed UL on B(K+ → l+N) established for each HNL mass hypothesis UL on coupling computed from UL on BR UL on |U2 e| in (10 7 −, 10 6 −) for mN in (170, 448) MeV/c2 and on |U2 μ| in (10 7 −, 10 6 −) for mN in (250, 373) MeV/c2 [1] Results improve world existing limits on HNL production searches on |U2 e| (over whole mass range) and on |U2 μ| (for masses above 300 MeV/c2) 2016-2018 data collected by NA62 much larger than 2015 sample Opportunity to further improve existing limits on |U2 e| and |U2 μ| Published in Physics Letters B 778, 137–145 (2018) [1] | poster |
PROVISIONAL FINDINGS - Emergency Laws are Political Legal Regimes They are not temporary but permanently incorporated into the legal system 1. 2. They are performative, to declare them is also to create the emergency 3. They are under- performing War - First World War Insurgency - Algerian War Terrorist Threat - 2015-2016 Dictatorship - Vichy’s Government Riots & Violences - 1985 New Caledonia - Kanaky Disaster - COVID-19 How to react when the state security, when the public order is threatened? When the legal frame appears insuficient to properly answer to an unexpected crisis so important that it could lead to the political and social unstability of the nation? In these situation , the State often end up relying on Emergency measures taking the form of regimes of exception. Through Legal History, and with fundamental interdisciplinary elements from sociology and from political sciences, the goal of this research is to analyse these exceptionnal regimes through their applications in France in the last century. It analyses, by observing ke y periods of the application of emergency laws, how did they impact the legal frame of normalcy, the Fundamental Rights and Legal a nd Political Thought in general ? Louis Bremond louis.bremond@UGent.be WHAT ? - Case Study of applied Emergency Laws WHEN ? - 1914-2024 WHERE ? - France, its territories and its former colonies Taming the Black Swans A Century of Law and Emergency in France 4. They are “field regime” and variates greatly depending on the context | poster |
Rapana venosa Rapană CUM O RECUNOAȘTEM? Familia Muricidae, Clasa Gastropoda Gastropod de talie mare, cu cochilia globuloasă, cu spira evidentă, formată din 3 - 4 anfracte, care cresc încet şi regulat. Ultimul anfract este foarte dezvoltat, mult dilatat. Apertura este foarte largă, de formă ovală, strălucitoare în interior, de o culoare portocalie- roşcată; marginile aperturii prezintă cute. Ombilicul este mărginit de o îngroşare puternică, care formează o creastă pe marginea inferioară a cochiliei. Dimensiunile maxime ale cochiliei sunt de 7 - 12 cm înălţime şi 9 cm lăţime. Coloritul este brun-roşcat, adesea cu benzi brune sau striuri colorate mai intens. Specie răpitoare, bentală, are un regim nutritiv flexibil consumând atât hrană vie cât și organisme aflate în descompunere. În alimentație predomină stridiile și midiile. Activitatea metabolică scade semnificativ în perioada rece a anului (toamna-iarna) când se afundă în nisip, mâl sau se adăposteşte în crăpăturile stâncilor fixându-se foarte strâns cu talpa de substrat. Perioada de reproducere durează din aprilie până în septembrie. Pontele sunt depuse sub forma unor cocoane semitransparente cu aspect de ciorchine. Numărul ouălelor într-o capsulă variază între 200 – 800. În medie o rapană depune 400 - 600 de capsule care sunt legate între ele, iar durata de formare a unei ponte este de 2 - 3 zile. Foto credit: https://ro.wikipedia.org/wiki/Rapan%C4%83#/media/Fi%C8%9 9ier:Rapana_Black_Sea_2008_G1.jpg https://ro.wikipedia.org/wiki/Rapan%C4%83#/media/Fi%C8%9 9ier:Rapana_venosa_01.JPG https://www.researchgate.net/publication/272992445_Dyna mics_of_Rapana_venosa_VALENCIENNES_1846_Gastropoda_Mu ricidae_Population_in_the_Black_Sea/figures?lo=1 http://ukrbin.com/index.php?id=339780 https://www.inthemoodforfood.fr/en/odessa-food-guide- ukraine/ Eclozarea larvelor se realizează după o lună de la reproducere. O perioadă larvele înoată activ în masa apei, perioadă în care se hrănesc intens cu ciripede şi, ulterior, se aşează pe fund. Activitatea fiziologică se intensifică la începutul verii, când execută deplasări active în căutarea hranei prin intermediul piciorului musculos, cu o viteză medie de 30 cm/min. În această perioadă execută migraţii ample pe verticală şi poate fi întâlnită între 0,5 - 30 m adâncime. Capsule cu ouă | poster |
Probing Effect of External UV Radiation on Young Stellar and Substellar Mass Objects: Is Orion a Special Place for Observing External Photoevaporation of Disks? Orion A Star Forming Regions NGC 1977 provides a milder radiation environment than Orion Nebula Cluster (ONC): ONCprovides strong radiation environment (with multiple O stars), since a B1 star is the highest mass star in NGC 1977. Compared to θ1 Ori C (O6.5V), surroundings of 42 Ori (B1V) has ~30 times lower FUV field, yet we find photoevaporation playing an important role on YSO evolution. L1641 which has similar age as NGC 1977 and ONC provide weaker UV environment. Proplyds in NGC 1977 30’ north of Orion Nebula Age: ~1-1.5 Myr (similar to ONC) Difference between Orion Nebula and NGC 1977: No O star! B1V is the earliest type star in the region FUV field ~ 3,000 G0 Proplyds are found for the first time near a B star! J. Serena Kim (Univ. of Arizona), Min Fang (Univ. of Arizona), Josh Eisner (Univ. of Arizona), Ilaria Pascucci (Univ. of Arizona), Daniel Apai (Univ. of Arizona), Cathie Clarke (IoA, Cambridge), Stefano Facchini (MPE), Carlo Manara (ESA/ESTEC), Marina Kounkel (WWU), Kevin Covey (WWU), NExSS/EOS team, and APOGEE2-YSO team Orion B 1 Myr Barnard’s loop OB 1a 6-10 Myr OB 1b 5 Myr Orion Nebula σOri 3-4 Myr NGC 2068 2071 NGC 2024 NGC1980 NGC1977 ~1-1.5Myr ~1-1.5 Myr 1-2 Myr ~1.5 Myr 25 Ori 7-10 Myr L1641 Photoevaporating Protoplanetary Disks Is Orion SFRs at special time to observe Photoevaporating YSOs? Orion Nebula has the most number of extensively studied proplyds around Trapezium stars, especially around θ1 Ori C (O6.5). There are only a few proplyds known in other star forming regions all around O stars (e.g.,Balog et al. 2006, Koenig et al. 2006, Fang et al. 2012). NGC 1977 has the 2nd most number of proplyds found so far. There are handful of proplyds in other regions but in small numbers. Disks in ONC near θ1 Ori C are truncated and smaller than other SFRs! A Candidate Planetary Mass Proplyd in ONC: Proplyd 133-353 Star forming regions and approximate ages of SFRs in Orion. Background image is courtesy of Roberto Bernal Andreo In the table… #4 and 5 has K ~ 17-18mag (from UKIRT, Kim et al. in prep). These are below Spitzer detection limit (Megeath et al. 2012) and we place an upper limit: Mproplyd< 0.015Msun Proplyds in NGC 1977 (HST/ACS image F658N) from Kim et al. (2016). The yellow arrows point toward the B1 star, 42 Ori. NGC 1977. The blue stars are the locations of B stars and the red circles are the locations of proplyds (Kim et al. 2016). The other symbols are the candidate YSOs (Fang, Kim et al. in prep.) Modeling of proplyds Model: from Facchini et al. (2016) For B1 star (~10 M⦿, NLy = 1045/s, LFUV= 2x1037 erg/ s.) (Diaz-Miller et al. 1998, Armitage 2000) FFUV ~ 3000 G0 at d = 0.2-0.3 pc from B1 star Ṁphot ~ 10-8 - 10-9 M⦿ yr-1 Rdisk ~ 40 - 50 AU RIF ~ 70 - 400 AU for Rdisk ~ 40 – 50 AU References Balog, Z., Rieke, G. H., Su, K. Y. L., et al. 2006, ApJL, 2006, 650, 83 DaRio, M.. Tan, J. C., Covey, K. R. et al. 2016, ApJ, 818, 59 Eisner, J. et al. 2018, ApJ, 860, 77 Facchini, S., Clarke, C. J., & Bisbas, T. G. 2016, MNRAS, 457, 3593 Fang, M. van Boekel, R., King, R. R. et al. 2012, A&A, 539, 119 Fang, M., Kim, J. S., Pascucci, I. et al. 2016, ApJ. 833, L16 Fang, M. Kim, J. S., Pascucci, I. et al. 2017, ApJ, 153, 188 Kounkel, M. et al. 2018, AJ, accepted Kim, J. S., Clarke, C. J., Fang, M., & Facchini, S. 2016, ApJ, 826, L15 Megeath S. T., Gutemuth, R., Muzerolle, J. et al., 2012, AJ, 144, 192 This work benefits from the EOS NExSS collaboration. We acknowledge the European Research Council under ERC-2013-ADG. The HST data presented in this paper were obtained from the Mikulski Archive for Space Telescopes ( MAST) at https:// archive.stsci.edu/hst/ . Background image credit: ESA/NASA/JPL-Caltech Proplyd 133-353 is near θ1 Ori C at the center of ONC. Our Near-IR spectroscopic data found it to be M9.5 And have a mass of ~13 Jupiter mass at an age o | poster |
Methodology Factors Related to Prehospital Delay in the Presentation of Acute Stroke and Level of Awareness among Stroke Patients in a District Setting SH Lim1, TL Tan1, PW Ngo1, LY Lee1, SY Ting2, HJ Tan3 1Medical Department, Hospital Seri Manjung, Perak, Ministry of Health, Malaysia 2Clinical research Department, Hospital Seri Manjung, Perak, Ministry of Health, Malaysia 3Neurology Department, Hospital Kuala Lumpur, Kuala Lumpur, Ministry of Health, Malaysia P-152 NMRR-19-2047-49080 (IIR) Introduction • Early presentation to hospitals has been shown to predict better functional outcomes in stroke patients. • Lack of these local data poses great challenge in the mission of establishing more acute stroke ready hospitals among district populations. • Aims: To examine how stroke patients in district setting in Malaysia react to stroke symptoms and factors contributed to their prehospital delay to seek treatment. Characteristics n (%) Age in years, mean(SD) 59 (12.7) Male gender 65 (63.7) Ethnicity Malay Chinese Indian Others 67 (65.7) 26 (25.5) 7 (6.9) 2 (1.9) Comorbidities Hypertension Diabetes mellitus Dyslipidemia Ischemic heart disease Previous stroke None 73 (71.6) 39 (38.2) 29 (28.4) 15 (14.7) 18 (17.6) 21 (20.6) NIHSS score, median(IQR) 5 (6.0) Perception of stroke Yes No Not sure 39 (38.2) 21 (20.6) 42 (41.2) Patients’ perception of symptom & severity Limb weakness Severe Facial asymmetry Severe Dysarthria Severe 92 (89.3) 59 (57.8) 31 (30.1) 11 (10.8) 56 (54.4) 25 (24.5) Aware of thrombolysis service 4 (3.9) Subtype of stroke LACI PACI POCI TACI 82 (80.4) 11 (10.8) 6 (5.9) 3 (2.9) Decision delay in minutes, median(IQR) 120 (645.0) Transport delay in minutes, median(IQR) 161 (192.5) Prehospital delay in minutes, median(IQR) 364 (957.5) Table 1: Demographic and clinical characteristics Results Variables Adj. OR (CI 95%) P value Ethnicity Malay Chinese Indian Others 11.30 (1.93, 66.19) 4.06 (0.64, 25.65) 1.00 0.60 (0.02, 15.00) 0.019 0.007 0.136 0.753 No previous stroke 4.15 (1.21, 14.25) 0.024 Not aware of thrombolysis service 17.12 (1.28, 229.17) 0.032 Table 2: Significant predictors for PREHOSPITAL DELAY by multivariate logistic regression Variables Adj. OR (CI 95%) P value No comorbid 8.63 (1.40, 53.22) 0.020 NIHSS score 0.87 (0.78, 0.96) 0.006 Perception of stroke Yes No Unsure 1.00 3.67 (0.95, 14.17) 3.78 (1.24, 11.55) 0.040 0.059 0.020 Not aware of thrombolysis service 15.27 (1.10, 211.46) 0.042 Table 3: Significant predictors for DECISION DELAY by multivariate logistic regression 1. Patients without any comorbidity had higher likelihood of decision delay as they were never screened for any cardiovascular risk factors or received any clinic consultations prior to stroke. 2. No association was found between having at least one cardiovascular risk factor with prehospital or decision delay, suggesting the lack of stroke education for patients who are at risk of stroke. 3. Our study population had poor awareness and knowledge for stroke as evidenced by less than half of the patients were able to recognize FAST symptoms as stroke. 4. Those who perceived stroke symptoms correctly had shorter decision time compared to those who were unsure, but the former did not have shorter prehospital delay. This shows that even good knowledge of stroke symptoms is insufficient as there was a significant discrepancy between awareness and action taken following stroke. 5. Reasons for decision delay were symptoms being mild, unable to get help, symptoms being perceived as self-limiting and not knowing how to react. 6. Decision delay is not significantly shorter in patients who perceived their symptoms to be severe. In conclusion, there is a substantial lack of knowledge and lackluster response to stroke among our studied populations. Various strategies are required in the future not only to disseminate knowledge of stroke, but also to modulate the public behaviour as these represent the main obstacles towards early hospital presentation a | poster |
IMF-σ: core & power-law galaxies Our analysis reveals a separation in the IMF-σ relation for M87 and NGC7619 (squares), compared to NGC1332 and NGC0307 (circles). Larger symbol sizes indicate smaller radii. The former are pressure-supported core galaxies with luminosity profiles that turn over at a certain radius while the latter are rotation-supported power-law galaxies containing surface brightness profiles with a steep power-law. Power-law galaxies appear to have more bottom-heavy IMFs and higher M/L than core galaxies of the same σ (see also [6]). While σ drives the overall trend for galaxies, offsets are seen in the relation for different galaxies. We are adding more core and power-law galaxies to the sample and aim to explore any differences in radial gradients between them. Method We create high S/N Voronoi binned spectra [1], subtracting emission lines and deriving kinematics using PPXF [2]. We measure optical absorption features as well as perform full spectrum fitting with ALF [3], example fits shown below. We obtain consistent results from both for age, metallicity, Mg abundance using different stellar population models [3][4]. Introduction The stellar initial mass function (IMF) has implications for a wide range of problems in astrophysics and is one of the largest uncertainties when analysing the integrated light of galaxies. Through MUSE we focus on a galaxy-by-galaxy approach to study detailed spatial variations in age, metallicity, individual element abundances, and the low-mass IMF slope by fitting the full spectrum with stellar population models. We perform the analysis for galaxies with different kinematics and explore trends with velocity dispersion. M87: elliptical, slow rotator Having masked the contaminated jet and central region, we find a constant age~13 Gyrs, [Mg/Fe]~0.4 dex, strong negative gradients in [Fe/H] and [Na/Fe], and mild negative gradients in the IMF slope and M/L. The IMF is slightly steeper than Salpeter in the centre and Salpeter at 0.5 Re. Comparing M/L from dynamical models for M87 reveals a value of ~6.5 in the centre, which is lower than the results from stellar population analyses (see also [5]). NGC1332: E/S0, fast rotator This galaxy, viewed edge-on, also has an old stellar population with a very shallow gradient out to 1 Re, and a negative metallicity gradient. [Mg/Fe] is lower at ~0.3 dex. A steep negative gradient is found in [Na/Fe] with maximum values of 0.6 dex and a slope of -0.3 dex/Re. The low-mass IMF has a slope of 3.4 in the centre, decreasing to 3 at 1 Re, corresponding to a very high central M/L ~10-15 in the V band. NGC1332 shows an interesting v-h3 correlation which suggests the presence of a bar, viewed end-on. The stellar population maps also show some asymmetry, supporting this. Spatially-Resolved Stellar IMF in a Sample of Kinematically Distinct MUSE Galaxies Taniya Parikh⭑, Roberto Saglia, Jens Thomas, Kianusch Mehrgan, Ralf Bender Max-Planck-Institut für extraterrestrische Physik, Garching, Germany ⭑tparikh@mpe.mpg.de 1 Cappellari & Copin 2003, MNRAS, 342, 345 2 Cappellari 2017, MNRAS, 466, 798 3 Conroy et al. 2018, ApJ, 854, 139 4 Thomas, Maraston & Johansson 2011, MNRAS, 412, 2183 5 Sarzi et al. 2018, MNRAS, 478, 4084 6 Bernardi et al. 2019, MNRAS, 489, 5633 | poster |
Resonances in doubly anisotropic, high-index nanoplatelets Bingying You, Tom T. C. Sistermans, and Alberto G. Curto background: n=1.0 nab = 4.5 Field monitor (for multipole expansion) Total-field/scattered-field (TFSF) source Scattering field monitor nab = 4.5 nab = 4.5 nz = 1.5 nz = 4.5 260 nm 230 nm 500 0 1 2 3 600 700 800 Wavelength (nm) 500 600 700 800 0 1 2 3 90 nm 60 nm Wavelength (nm) Scattering cross section ( 105 nm2) nz = 4.5 nz = 1.5 500 600 700 800 Wavelength (nm) 0 1 2 3 Anisotropy Diameter Height MoS2 layered structure MD ED 0 3 4 2 1 k E H scattering cross section (10⁵ nm2) 0 3 4 2 1 Total k E H MQ EQ 0 3 4 2 1 EQ ×10 ×10 MQ 500 700 600 800 Wavelength (nm) k E H 500 500 600 700 800 600 700 800 The two peaks exhibit different sensitivities to changes in anisotropy, which is a different behavior compared to changes in geometry Therefore, an in-plane magnetic dipole resonance is more sensitive to anisotropy than an in-plane electric dipole resonance Magnetic dipole is more sensitive to changes in anisotropy Multipolar decomposition Optical anisotropy plays a crucial role in the manipulation of light. However, its strength is limited to low values in conventional materials. Transition metal dichalcogenides possess both high refractive index and giant birefringence due to their layered structure. Here, we study the resonant optical response of individual nanoplatelets. We investigate the distinct impact of changing geometry and birefringence on the tunability of different resonances. We use a multiple expansion for analyzing the contribution of electric and magnetic dipole responses to resonances in nanoplatelets. These electric and magnetic multipolar resonances are sensitive to geometry and anisotropy in distinct and different ways. We envision that films consisting of disordered but oriented nanoplatelets could be used to enhance and direct light scattering and light emission, with applications in light-emitting devices and random lasers. Current and anisotropy Normalized current |Jz| Normalized current |Jx| ED 50% ED + 50% MD 90% ED + 10% MD λ = 521 nm, nz = 1.5 λ = 521 nm, nz = 4.5 λ = 690 nm, nz = 4.5 X z 0 0 10 20 30 60 100 nm Resonances dominated by electric and magnetic dipoles Anisotropy affects out-of-plane electric field/current Different resonances for different illumination conditions Understanding the impact of anisotropy Total: scattering cross section ED: electric dipole MD: magnetic dipole Total 500 600 700 800 Wavelength (nm) 0 0.5 1 1.5 2 2.5 Scattering cross section (105 nm2) MD ED Scattering with varying anisotropy Simulation configuration Layered structure Birefringence Ermolaev et al. Nat Commun 12, 854 (2021) Tatsuki,.et al. OSA Continuum 5, 4 (2021) weak interlayer force strong intralayer interactions large intrinsic Δn (nab-nc) high refractive index Giant anisotropy between ab-plane and c-axis Impact of changing anisotropy on resonances Geometrical tunability of resonances Resonances in nanoplatelets photonics.intec.ugent.be nano-optics.be Photonics Research Group, Ghent University-imec, Belgium | poster |
Zentraler Fonds für eine dezentrale Forschungsorganisation Open-Access-Publikationsfonds der Leibniz-Gemeinschaft www.leibniz-gemeinschaft.de Stand: September 2016/ Die erfolgreichen Anträge verteilen sich ungleichmäßig über die Sektionen der Leibniz-Gemeinschaft. Verteilung der Kosten pro Sektion Die zehn am häufigsten vertretenen Verlage. Grundlage: 144 bewilligte Förderungen. Verteilung der Kosten pro Artikel Sektion Motivation • Umsetzung von Open Access an Instituten konkret fördern • Open-Access-Publizieren der Wissenschaftler/ innen ermöglichen • Open-Access-Anteil erhöhen - erklärtes Ziel der Leibniz-Gemeinschaft • Erfahrungen mit zentralem Fonds sammeln, Zukunftsmodell planen • Finanzierung: Publikationsgebühren aus Strategie- fonds der Leibniz-Gemeinschaft; Personalaufwände von TIB, ZB MED, ZBW Erfahrungen • positives Feedback der Nutzer • bisher keine Impulse für den Auf- oder Ausbau eigener Institutsfonds • in Einzelfällen in Einzelfällen Fehlentwiclung (z. B. Abbau institutioneller Förderung) • effiziente und professionelle Antragsprüfung und finanzielle Abwicklung • erstmals zentrale Daten zum Publikationsverhalten im Hinblick auf APC-basiertes OA • Vorteile eines zentralen Fonds sichtbar • wie bei anderen Einrichtungen: APC-Management aufwändig • Ausreißer erschweren Arbeit (fehlende CC-Lizenz, hohe Kosten) • aufgrund fehlender absoluter Kostengrenze vergleichsweise hohe durchschnittliche APC-Höhe Fortsetzung • Auswertung und Dokumentation der Erfahrungen • Diskussion von Verstetigungsmodellen • Ergänzung durch zentrale Verhandlungen über Erleichterungen • dezentrale Struktur der Leibniz-Gemeinschaft zu berücksichtigen Zentrale Kennzahlen • 144 geförderte Artikel • in 71 verschiedenen Zeitschriften • nahezu alle Artikel verfügen über einen DOI • 142 Artikel unter Creative-Commons-Lizenz, fast ausschließlich CC-BY-Lizenz • Nachweis in LeibnizOpen (Texte) und bei Open APC Initiative (Kosten) Verlag Artikel Springer Nature 47 PLOS 32 Frontiers 10 MDPI 10 Wiley 6 Copernicus Publications 4 OSA 4 AAAS 3 AIP Publishing LLC 3 IOP 3 Autor/innen Marco Tullney Technische Informationsbibliothek (TIB) - Leibniz-Informationszentrum Technik und Naturwissenschaften und Universitätsbibliothek orcid.org/0000-0002-5111-2788 Anita Eppelin Geschäftsstelle der Leibniz-Gemeinschaft orcid.org/0000-0003-3184-5930 0 10 20 0 1000 2000 3000 4000 Artikel Artikel Euro Euro ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ●● ● 0 1000 2000 3000 4000 ● ● ● ● ● A − Geisteswissenschaften und Bildungsforschung B − Wirtschafts− und Sozialwissenschaften, Raumwissenschaften C − Lebenswissenschaften D − Mathematik, Natur− und Ingenieurwissenschaften E − Umweltwissenschaften 0 20 40 60 80 A − Geisteswissenschaften und Bildungsforschung B − Wirtschafts− und Sozialwissenschaften, Raumwissenschaften C − Lebenswissenschaften D − Mathematik, Natur− und Ingenieurwissenschaften E − Umweltwissenschaften 0 500 1000 1500 Leibniz−Publikationsfonds Open APC Initiative Durchschnittliche Kosten (in Euro) | poster |
The Astromaterials Data System: A Comprehensive Platform for Preservation, Access, and of Mining Analytical Data of Extraterrestrial Samples Peng Ji, Kerstin Lehnert, Columbia University Cindy Evans, Ryan Zeigler, NASA Johnson Space Center Contact: pengji@ldeo.columbia.edu The Astromaterials Data System (AstroMat) is a joint project of the Geoinformatics Research Group at the Lamont-Doherty Earth Observatory and NASA’s Johnson Space Center (JSC) to develop a comprehensive data system that supports discovery, access, preservation, and analysis of analytical data generated by the study of extraterrestrial materials curated by JSC’s Astromaterials Acquisition and Curation Office, including lunar samples, meteorites, cosmic and interplanetary dust, solar wind, and other samples. AstroMat continues the NASA-funded MoonDB project, expanding data compilation to all JSC astromaterials collections, refining and augmenting the MoonDB database schema, and upgrading MoonDB applications to provide both integrated and specialized access to the JSC astromaterials collections. AstroMat is developed as an ecosystem that will help researchers, data curators, and developers track, manage, access, search and explore data and comprises the following components: - AstroDB: Storage database (PostgreSQL) with rich metadata content that integrates (fuses) data previously scattered across the scientific literature and in online PDF documents, making the data easily searchable and minable as a single data product with human and machine-readable interfaces. - AstroRepo: Repository for user-submitted digital content from astromaterials research (analytical data, data synthesis, images, models, etc), will seek CoreTrustSeal certification for Trusted Data Repositories. Includes RepoDB as the document database (MongoDB). - A series of web applications for specific purposes: - AstroAPIs: serves as a bridge between the storage database and all applications that retrieve data from the AstroDB database. - AstroAdmin: enables curators to create, curate, organize, annotate, and manage highest quality data content including metadata and analytical data. - AstroSearch, AstroRef, AstroPages and AstroVis provide interfaces for users to browse and explore the content of AstroDB, select samples and data that they are interested in, view and browse them, and download them in a useful format. ESIP Winter Meeting Jan 2019, DC AstroRef: Browsing the content of Astromat | poster |
Results • Different result patterns between L2 learners and native speakers of Chinese in terms of the Stroop facilitation effect were found. • Critically, Stroop facilitation effect was found in native speakers, but not in L2 Chinese learners in the S-T+ condition. Research questions 1) Can L2 learners of Chinese automatically process tonal information in a similar manner as native speakers during visual word recognition? 2) Does the involvement of the production system impact the processing of tonal information in different ways in L1 and L2 visual word recognition? Chinese tones • Four common lexical tones marked as in ā á ǎ à • Tones serve as a critical part of Chinese phonology • Tones are necessary if learners want to master Chinese as an L2 Automaticity • According to some researchers, if a linguistic feature has been acquired implicitly, it should be processed automatically (e.g., Jiang, 2004). -> This study, thus, explores automatic tonal processing in L2 and L1 during visual word recognition. Automatic tonal processing in L1 Chinese • Li, Lin, Wang, & Jiang (2013) • Native Chinese speakers were tested in a naming Stroop task. • Tonal information is automatically processed in L1 Chinese visual word recognition, so is segmental information (which is similar to vowels and consonants in English). Automatic tonal processing in L2 Chinese • It is understudied. • Li, Wang, Davis, & Guan (2019) reported that L2 learners do not represent and access tones in a comparable manner as the native speakers. However -- • Li et al. (2019) may be insufficient to reflect how L2 tones are represented and accessed because they used the homophone judgement task. • It replies on metalinguistic knowledge to complete the task. • It allows strategic processing. • It is hard even for native speakers of Chinese (Taft & Chen, 1992). Studying L2 tonal processing visual word recognition will reveal -- • How phonological information is represented and/or processed in L2. • The similarities and/or differences in how phonological information is represented and/or processed in L1 and L2. Rongchao Tang1, Naoko Witzel1, Xiaomei Qiao2, & Jia Chen2 1University of Texas at Arlington 2Shanghai University of Finance and Economics Automatic tonal processing in L2 Chinese learners during silent reading Introduction Experiments 1 & 2, Naming Stroop Task Discussion Selected References Acknowledgements Summary of results Contact: rongchao.tang@mavs.uta.edu Design • A button-pushing Stroop task, i.e., press button to indicate the ink color of Chinese characters • A Pinyin identification task • Confirmed that participants have the explicit knowledge of the stimuli • Same six conditions following Exps. 1 & 2 Participants • Experiment 1: 18 native Chinese speakers • Same as Li et al. (2013) • Experiment 2: 27 L2 leaners of Chinese • Passed HSK5 (high proficient L2 Chinese learners) • None of them reported having deficiencies in identifying color. Materials for Experiments 1 & 2 • 20 Chinese monomorphemic characters This study was supported in part by the CoLA Dean’s Award for Research, University of Texas at Arlington,, awarded to first author, Rongchao Tang. • Robust Stroop facilitation effects in the S-T+ conditions for native speakers, but not for L2 learners -> L2 learners cannot automatically process tonal information, while native speakers can. Results Experiments 3 & 4, Button-pushing Stroop Task • Li, C., Lin, C. Y., Wang, M., & Jiang, N. (2013). The activation of segmental and tonal information in visual word recognition. Psychonomic bulletin & review, 20, 773-779. • Li, C., Wang, M., Davis, J., & Guan, C.Q. (2019). The role of segmental and tonal information in visual word recognition with learners of Chinese. Journal of Research in Reading, 42, 213-238. • Stroop, J. R. (1935). Studies of interference in serial verbal reactions. Journal of Experimental Psychology, 18, 643-662. • Taft, M., & Chen, H. C. (1992). Judging homophony in Chinese: The influence | poster |
CSSI Elements: Development of Assumption-Free Parallel Data Curing Service for Robust Machine Learning and Statistical Predictions PI: In-Ho Cho, Co-PI: Jae-Kwang Kim Institutions: Iowa State University Award #: 1931380 NSF CSSI PI Meeting, Washington D.C., July 25-26, 2022 Grand Challenges Research Objective Proposed Methods Results User-Friendly Service Conclusions • Incomplete data issue is everywhere in broad science and engineering • Theories and methods of missing data curing (called “imputation”) is limited to small data • Naïve imputation may substantially hamper the accurate machine learning (ML) and statistical learning (SL)-based predictions (see Fig below) • Lack of theories and software for large/big incomplete data curing Fig. Positive impact of the proposed data curing method (FHDI) on statistical learning (SL) and ML predictions: Generalized additive model (GAM); Extremely randomized trees (ERT); Artificial neural network (ANN). Root mean square error (RMSE) is shown. • Develop a new community-level large data curing service running on NSF Cyberinfrastructure (XSEDE) and local HPC • No restriction of data sizes, types, high- dimensionality; No distributional assumptions or expert knowledge on data science required • Pursue a purely data-driven imputation by developing the ultra data-oriented parallel fractional hot deck imputation (UP-FHDI) ➤Assumption-Free, General Data Curing; Only Observed Data Are Needed for Imputation (thus, “Hot-deck”) ➤Provide “Cured” large/big data set for convenient subsequent ML and SL Ultra Data-Oriented Parallel Fractional Hot Deck Imputation (UP-FHDI) [Ultra Data: Big-n & Big-p] [Step 1] Parallel Imputation Cell Construction Hybrid Data (Continuous & Categorical) [Step 2] Imputation Cell’s Joint Probability Parallelized Modified EM Algorithm [Step 3] Fractional Hot Deck Imputation Parallelized Donor Selection with KNN [Step 4] Parallel Variance Estimation Parallelized Jackknife & Parallel Linearization [Step 0] Sure Independence Screening (SIS) Selectively Done for big-p (high-dimensional) Data Data: U(size, variables, missing rate) Fig. Scalability of UP-FHDI • Deployment of the UP-FHDI on NSF XSEDE • Graphical User Interface (GUI) for UP-FHDI • Open data sets, examples, and manual videos big-n data big-p data big-n & big-p data • UP-FHDI has been developed for improving prediction accuracy of ML and SL with Ultra incomplete data (up to millions of instances and 10,000 variables) • The program is deployable on NSF XSEDE and local HPC • Serial version R Package FHDI available on CRAN Acknowledgement • PIs work supported by NSF OAC-1931380 • HPC at Iowa State University: Condo supported by NSF MRI grant CNS-1229081 and CRI-1205413; Nova by MRI-1726447 and 2018594 ULTRA DATA Fig. UP-FHDI Can Tackle Three Data Types References of the PIs • Yang et al., 2022, IEEE TKDE (under 2nd review) • Yang et al., 2020, IEEE TKDE • Song et al., 2019, IEEE TKDE • Im et al., 2018, The R Journal Adopted OOOPS (Huang and Liu, 2020) Fig. Average Standard Error Fig. RMSE Synthetic Big-p Data (n=10,000, p=0.1 million, Missing=0.3) with increasing randomness (SD) in data Mean Abs Error GUI-App for UP-FHDI Fig. Accuracy of UP-FHDI Fig. New Variance Est. Method’s Efficiency Test Data Sets | poster |
574 Uruguayan savanna 652 Central Anatolian steppe and woodlands 703 Northern Anatolian conifer and deciduous forests 799 Northeast Spain and Southern France Mediterranean forests 686 Western European broadleaf forests 664 European Atlantic mixed forests 654 Central European mixed forests 647 Baltic mixed forests 651 Celtic broadleaf forests Study sites Litter decomposition in ponds across a large latitudinal gradient Relation to hydroperiod Decomposition rate (A) and stabilization factor (B) were lower in temporal ponds than in permanent ponds. Ecoregions based on Olson et al. 2001 Conclusions 1. In contrast to soils, the results suggest that ponds favor carbon sequestration. 2. Within the studied latitudinal range, the vegetation land cover might be more relevant than latitudinally climate-related factors 3. The existence of drought periods in temporal ponds limits the decomposition process. 4. Total Phosphorus in water positively correlated with k , showing nutrient influence on decomposition dynamics. References Martín, L.1 *, Pastor, A.1, Cuenca-Cambronero, M.2, Antón-Pardo, M.3, Colina, M.4,5, Dede, C.6, Demierre, E.7, Fahy, J.C.7, Girard, L.8, Greaves, H.9, Lemmens, P.10,11, Meerhoff, M.4,12, Mülayim, E.B.6, Patmore, I.R.9, von Plüskow, L.M.10,11, Wijns, R.10, Brucet, S.2,13, Boix, D.1, Romaní, A.M.1 1GRECO, Institute of Aquatic Ecology, University of Girona, Spain; 2Aquatic Ecology Group, University of Vic - Central University of Catalonia, Spain; 3Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, Spain; 4Departament of Ecology and Environmental Management, Centro Universitario Regional del Este-Universidad de la República, Uruguay; 5Department of Ecology, Radboud Institute for Biological and Environmental Sciences, Radboud University, The Netherlands; 6Limnology Laboratory, Biological Sciences Department, Middle East Technical University, Turkey; 7Ecology and Aquatic Systems Engineering group, HEPIA, University of Applied Sciences and Arts Western Switzerland, Switzerland; 8Agroecology and Environment Research Unit, France; 9University College London (UCL) Pond Restoration Research Group, Department of Geography, Gower Street, London; 10Laboratory of Freshwater Ecology, Evolution and Conservation, KU Leuven, Belgium; 11Leibniz Institute für Gewasserökologie und Binnenfischerei (IGB), Germany; 12Department of Ecosciences, Aarhus University, Denmark; 13ICREA, Catalan Institution for Research and Advanced Studies, Spain Ponds play an important role in the process of plant litter decomposition, contributing to the carbon cycle. Ponds are highly vulnerable to pollution and climate change, which can affect decomposition. The aim of this project was to quantify the potential for microbial litter decomposition rate in ponds along a latitudinal gradient in different ecoregions, to identify the main drivers of its variability by using the Tea Bag Index (TBI), defined by the different decomposition of a labile tea (green tea) and a recalcitrant tea (rooibos). Introduction Relation to latitude We observed contrasting patterns of decomposition parameters across the latitudinal gradient. While k (A) increased with absolute latitude, S (B) decreased. Relation to nutrients We observed a positive correlation between water total phosphorus (TP) and k (A), indicating the influence of nutrients on decomposition dynamics. In contrast, a negative relations between TP and S (B) was observed, but only with marginal significance. k (decomposition rate) proxy to mass- loss rate of plant litter organic mater. S (stabilization factor) refers to the inhibiting effect of environmental conditions on the decomposition. High values indicate increase carbon sequestration potential. A total of 250 ponds were selected, distributed across eight countries compassing nine ecological regions. The ponds were located at varying latitudes and exhibited diverse land-use intensities, including both permanent and intermittent | poster |
Putting Everything Together Ruslan Belikov1, Maxwell Moe2, Stephen Bryson1, Lily Zhao3, Jack Lissauer1 1NASA Ames Research Center, Moffett Field, CA 2University of Arizona, Tucson, AZ 3Flatiron Institute, New York, NY Folding in Other Effects and Priors Summary • Alpha Centauri AB is a promising system in the search for potentially habitable planets, representing the closest (by a large margin) Sun-like stars to the Solar System. • Planets can and do form around binary stars like Alpha Centauri, and the habitable zones of both stars are stable. However, planet formation around binaries may not be as efficient as around single stars • This work estimates the number of potentially habitable planets around Alpha Centauri AB system as 0.28−0.12 +0.25, but if at least one planet is confirmed, this number can rise to 1.2 −0.3 +0.7. A lot of uncertainty still remains Expected Occurrence Rates and Types of Planets Possible in the Alpha Centauri AB System Occurrence Rates from Kepler (around single and binary stars) Selected References Total expected number of planets [0.5-13 Re, 0-2.5AU] Expected number of Potentially habitable planets [0.5-1.5 Re, Kopparapu et al. 2013 conservative HZ] Combined single+binary occurrence from Kepler (per star) ~ 3 0.40−0.2 +0.5 after correction for binarity (per system, i.e. counting both stars) ~ 2 0.30−0.13 +0.27 after accounting for RV non- detections (both stars) ~ 2 0.28−0.12 +0.25 if NEAR candidate is real, and assuming it does not disrupt HZ (both stars) ~ 8 ~ 1.2 −0.3 +0.7 Ruled out by dynamical stability Ruled out by RV non-detections (note: this region boundary is very uncertain due to mass-radius relationship uncertainty) 1.92aCenBaCenA Caveat: due to numerous uncertainties, and evolving understanding of various effects, the above numbers are continuing to evolve a Cen AB Kraus et al. 2016: Moe and Kratter, 2020: Howell et al. 2021 a Cen AB Suppression factor ~0.3 Suppression factor ~0.25−0.10 +0.15 Due to observation bias against binaries, suppression factor estimates may be too aggressive hearth(aCenA) ~ hearth(aCenB) ~ 0.40−0.2 +0.5 x 1.44−0.12 +0.12 x 0.25−0.1 +0.15 = 𝟎. 𝟏𝟓−𝟎.𝟎𝟗 +𝟎.𝟏𝟗 Conservative HZ single+binary hearth Conversion to single- star hearth Binary suppression hearth(aCenAB) ~ hearth(aCenA) + hearth(aCenA) = 𝟎. 𝟑𝟎−𝟎.𝟏𝟑 +𝟎.𝟐𝟕 Alpha Centauri contains the closest (by a large margin) Sun-like stars to the Solar system Interest in observing aCen planets is mounting, e.g.: • VLT / NEAR (thermal IR direct imaging, Wagner et al. 2020) • JWST / MIRI (F1550C, 15.5mm, Beichman et al. 2020) • ALMA (astrometry, Akeson et al. 2020) • Toliman (astrometry w/ small space telescope, Bendek et al., Tuthill et al., ) • Window is opening for new RV observations due to increasing separation • Work is on-going to enable aCenAB direct imaging on Roman, IR/O/UV mission (Belikov et al., Bendek et al.) • 2021 Breakthrough Discuss conference was dedicated to Alpha Centauri: https://breakthroughinitiatives.org/initiative/5/discuss2021) MSWC Simulation SNWC Lab Demo : 1.4RE in HZ of aCenB (Gibbous phase) : 7RE @1.1AU, aCenA (quadrature) SAG13 (2016) Dulz et al. 2020 Bryson et al. 2021 • Meta-analysis of Kepler occurrence rates as of 2016 • Extended SAG13 to larger periods • Used for LUVOIR / HabEx yields • Latest / final analysis by Kepler team • Accounts for updated stellar radii, reliability, etc. • Treats occurrence rates in terms of instellation flux instead of period SAG13 / Dulz et al Bryson, low extrapolation Bryson, high extrapolation Conservative Kopparapu HZ, 0.5-1.5 Re 0.40−0.14 +0.48 𝟎. 𝟑𝟕−𝟎.𝟐𝟏 +𝟎.𝟒𝟖 0.60−0.36 +0.90 Optimistic Kopparapu HZ, 0.5-1.5 Re 0.58−0.2 +0.7 0.58−0.33 +0.73 0.88−0.51 +1.28 Wagner et al. 2020 R ~ 3.3 – 7 Re Maxwell Moe • If C1 is a real planet, then the suppression factor may not apply (or not as strongly) – aCenAB occurrence rates may become similar to single stars. • However, because C1 is in the HZ, it will “carve out” some of the HZ, leaving less space for rocky HZ | poster |
Introduction Queen Conch (Strombus gigas) are herbivorous gastropod mollusks; they live in shallow waters, and are commonly found in sand and sea grass substrates. They are significant to the Bahamas for a multitude of reasons. Economically, conch are important because they are the second largest fishery in the Bahamas (Danylchuck, 2003) . Queen conch are ecologically important because they keep the balance in the food chain by eating algae, and are a prey source for a variety of predators. Socially, conch are a symbol of Bahamian culture and a major food source. Despite their significance, conch populations have declined in recent years due to overfishing, degradation of sea grass beds, water pollution, and a lack of regulatory fishing mechanisms (Turnquest, 2012). Past studies comparing the population density of a marine protected area (MPA) and an unprotected area have shown that the density in the MPA is higher than the unprotected area (Stoner and Ray 1996). Previous Island School semesters have shown that there is good nursery habitat right off the cape in South Eleuthera, and the area is currently part of the proposed MPA. While conch juveniles settle in South Eleuthera, we are less aware of the abundance of adults. Queen conch are a density-dependent species, because of their internal fertilization, slow movement, and sex ratio of 1:1 (Stoner et al.2, 2012). In other words, they can only reproduce at a certain density. Therefore, if less than 47 individuals are present in a hectare (ha) there is little chance of reproduction occurring (Stoner et al. 1, 2012). In addition, conch reach sexual maturity after four years; this elongated process of sexual maturity adds to their decline because they cannot reproduce quickly. Methods Our research was conducted in and around the proposed MPA boundaries in Cape Eleuthera, Bahamas. Our methods were consistent with those of Stoner and Ray (1996). We conducted transects (1000m x 6m) based off of systematically randomized coordinates on a GPS (Fig. 1). Two snorkelers were towed behind a boat (Fig. 2), and signaled the presence and age of conch with hand signals, which were recorded by students on the boat (Fig. 3). Depth, time, and bottom type were also recorded. Some collected conch were brought back to the lab and measured (Fig. 4). Results A total of 114 queen conch were seen in 25 transects run in Cape Eleuthera, the Bahamas. The mean number of sub adults/ha were higher than the means of both the adults and juveniles/ha (Fig. 5). The highest densities of queen conch were observed in the western half of the proposed MPA grounds, reaching a maximum of 400 individual conch/ha(Fig. 6). However, despite this high number of conch, there were 12 transects where no conch were seen at all. 91% of the hectares observed did not have enough adult conch for reproduction. In addition, the highest densities of conch observed were in macroalgae substrates, not in sand and seagrass substrates. There was a mean of <1 adult conch/ha in sand substrates and there was a mean of 18 adult conch/ha in macroalgae substrates (Fig. 7). Discussion Our first hypothesis was that in the proposed MPA there would not be enough adult conch/ ha. for reproduction to occur. We formulated this hypothesis because it takes more than 47 conch/ha. for reproduction (Stoner et al. 1, 2012), and we think that density will be too low due to overfishing. 91% of the transects run (SP 12 and FA 12 data) did not have enough adults for reproduction, supporting our first hypothesis. Our second hypothesis was that we would find most adult conch in sandy substrates near reefs, because previous studies in the Caribbean found that adult conch use reefs in sand substrates for protection (Glazer and Kidney, 2004). We determined that most of the adult conch in South Eleuthera were found in macroalgae and seagrass substrates, rejecting our second hypothesis. We would like to suggest revising the boundaries of the proposed MPA here in Sout | poster |
g LeptOspirose bei Rindern in Niederösterreich (LORN) Ein gezielter Ansatz zur Verbesserung der Veterinärdiagnostik und zur Verhinderung einer beruflichen Exposition gegenüber Zoonosen Cynthia Sohm1,2,3, Clair L. Firth2, Thomas Wittek3, Romana Steinparzer4, Amélie Desvars-Larrive1,2,5 1 VetFarm der Veterinärmedizinischen Universität Wien, 2563 Pottenstein, Österreich 2 Abteilung für Öffentliches Veterinärwesen und Epidemiologie, Veterinärmedizinische Universität Wien, 1210 Wien, Österreich 3 Universitätsklinik für Wiederkäuer, Veterinärmedizinische Universität Wien, 1210 Wien, Österreich 4 Institut für veterinärmedizinische Untersuchungen, Österreichische Agentur für Gesundheit- und Ernährungssicherheit (AGES), 2340 Mödling, Österreich 5 Complexity Science Hub Vienna, 1080 Wien, Österreich Dieses Projekt wird durch das Land Niederösterreich gefördert. . Kontakt Cynthia Sohm (Doktorandin): Cynthia.sohm@vetmeduni.ac.at Acknowledgements • Leptospiren sind zoonotische Bakterien (Familie Spirochäten). • Leptospirose gilt in Europa als "(re-)emerging disease" [1]. • Die Übertragung der Leptospiren auf Mensch und Tier erfolgt zumeist durch den direkten Kontakt mit Urin oder Abortmaterial infizierter Tiere, oder indirekten Kontakt mit kontaminierter Umwelt. • Landwirt/innen, Jäger/innen und Tierärzt/innen haben ein höheres Infektionsrisiko als die restliche Bevölkerung [2,3]. • Rinder gelten als Reservoir des Serovars Hardjo, das am häufigsten zu chronischen Fruchtbarkeitsstörungen führt (Abb. 1). Eine Zirkulation von Leptospiren in der Herde könnte daher mit direkten und indirekten finanziellen Verlusten verbunden sein. • Über die Leptospirose bei Rindern in Österreich gibt es wenige Daten. • Die serologische Antikörper-Diagnostik stützt sich in Österreich auf „fremde“ Referenzstämme, obwohl die Weltgesundheitsorganisation WHO die Verwendung lokal isolierter Stämme zur Erhöhung der Empfindlichkeit des Tests nachdrücklich empfiehlt [4]. • Ziel des LORN Projekts ist es, regional pathogene Leptospiren-Stämme in Niederösterreich von infizierten Rindern in Betrieben und Schlachthöfen zu isolieren und die Sensitivität der serologischen Routinediagnostik für Mensch und Tier zu verbessern. • Zudem wird diese Studie auch ein verbessertes Verständnis der Prävalenz und der lokalen Epidemiologie dieser Zoonose in Niederösterreich ermöglichen. Bei Rindern verursachen Leptospiren häufig einen Milchleistungsverlust, der mit Fieber und Mastitis einhergehen kann. Die wichtigste Auswirkung hat eine Leptospiren- Infektion auf die Fruchtbarkeit: Sie senkt die Trächtigkeitsraten und erhöht die Abortrate. Der Abort erfolgt in der Regel 6-12 Wochen nach der Erstinfektion. In Herden, die sich zum ersten Mal mit der Krankheit anstecken, können bis zu 30 % der Tiere verwerfen. Bei chronisch infizierten Herden kann es zu einer Abortrate von bis zu 5 % kommen. Leptospiren siedeln sich in den Nieren an und vermehren sich auch dort. Verdächtige Tiere Schlachtkörper Nierengewebe Harn Datenübertragung und Analyse Gezielte Probenahme Max. 2 Stunden Max. 2 Stunden Max. 2-6 Stunden Genehmigung der Ethikkommission Inokulation in Kulturmedium (Feld) Isolierte lokale Leptospira Stämme Inokulation in Kulturmedium (Labor) PCR und Sequenzierung Phylogenie Genomdaten veröffentlichen • Wird zur Diagnose verwendet • Auf Anfrage geteilt (Labor, Universitäten) Schlachthof Niederösterreich Abb. 1: Typische Symptome der Leptospirose (Serovar Hardjo) bei Rindern. Teilnehmende niederösterreichische Tierärzte Problem Ziel PCR und Sequenzierung • Gezielte Probennahme: Nierengewebe und/oder Urinproben werden von: a) routinemäßig geschlachteten Rindern in niederösterreichischen Schlachthöfen, die als besonders infektionsgefährdet gelten (ermittelt durch statistische Auswertung serologischer Daten und Literaturrecherche) und b) Rindern in niederösterreichischen landwirtschaftlichen Betrieben, welche Symptome von Leptospirose zeigen, entnommen. • Genetik: Die Proben werden mittels PCR ges | poster |
MICRO-CT ANALYSIS APPLIED TO LIME MORTARS FOR DAMAGE ASSESSMENT DUE TO ACCELERATED WEATHERING C&E RESEARCH GROUP Dulce Elizabeth Valdez Madrid*, Nele De Belie, Veerle Cnudde Introduction Weathering of construction materials is one of the main causes for building deterioration and failure. Amongst some of the most important factors contributing to this outcome is the presence of salts in the system and their crystallization/dissolution behavior during ageing. These salts occupy the space within the pore network of the materials and manifests itself only once some damage has already been caused. It is of outmost importance to develop efficient methods for testing, evaluating and development of damage prediction of this phenomena to obtain better and more durable materials. Research questions – Can lime-based mortars show any representative damage due to salt damage? – Is it possible to assess and quantify damage caused by salt crystallization and weathering inside the porous media in a non- destructive manner? – Can a lab-based protocol imitate real life weathering damage without destroying the samples? Experimental conditions Six lime-cement mortars were tested for NaCl weathering by comparing two different contamination and propagation of damage regimes. These regimes consist of cycles of temperature and relative humidity variations followed by rewetting steps with water. Contact dulceelizabeth.valdezmadrid@ugent.be https://pprogress.ugent.be/index.php Universiteit Gent @ugent https://www.linkedin.com/in/dulzabeth/ Methodology For the non-destructive damage assessment, high resolution X-ray micro-computer tomography will be used as a non-traditional characterization technique before and after weathering [Fig. 1]. Weathering by salt damage tests were performed under similar experimental conditions to assess the impact of water and the length of temperature and relative humidity samples on the durability of the mortars. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under Marie Sklodowska-Curie project SUBLime [Grant Agreement n.º 955986]. 150.00 155.00 160.00 165.00 170.00 175.00 180.00 185.00 190.00 Weight (grams) 1:0:3 4:1:15 2:1:9 1:1:6 1:2:9 0:1:3 CYCLE 1 CYCLE 2 CYCLE 3ContaminationDryingWeatheringRewettingDryingWeatheringRewettingDrying Weathering 150.00 155.00 160.00 165.00 170.00 175.00 180.00 185.00 190.00 195.00 Weight (grams 1:0:3 4:1:15 2:1:9 1:1:6 1:2:9 0:1:3 CYCLE 1 CYCLE 2 CYCLE 3 CYCLE 4ContaminationDryingWeatheringRewettingDryingWeatheringRewetting WeatheringRewettingDrying WeatheringDrying Figure 3. Test 2 photographic documentation and weight monitoring results expressed in grams. Lower mass fluctuations and final mass gains are observed by the end of the 4th cycle (Fig. 5). Figure 2. Test 1 photographic documentation and weight monitoring results expressed in grams. Significant mass gains are observed by the end of the 3rd cycle (Fig. 5). 0.29 0.17 0.36 0.51 0.36 0.00 0.05 0.11 0.15 0.07 0.02 0.01 1.72 3.40 2.39 2.27 2.58 2.51 0.30 0.29 0.36 0.42 0.50 0.33 0.00 1.00 2.00 3.00 4.00 1:0:3-1 4:1:15-1 2:1:9-1 1:1:6-1 1:2:9-1 0:1:3-1 1:0:3-2 4:1:15-2 2:1:9-2 1:1:6-2 1:2:9-2 0:1:3-2 Relative difference of masses before and after testing (%) Debris (%) TEST 1 TEST 2 Figure 5. Final relative mass differences obtained before and after weathering (light blue), including final mass of total resulting debris (dark blue). DIFFERENCE IN MASS BEFORE AND AFTER TESTING Accelerated weathering There are currently some protocols and recommendations to test materials’ performance towards salt crystallization. Nevertheless, these are mainly focused on rocks, bricks and masonry units, aiming towards failure. This research intends to propose a more suitable protocol for mortars that allows for the characterization of the salt crystallization and its products in a more reliable and quantifiable manner, based on the RILEM TC ASC-271 recommendations. After 4th cycle Initial s | poster |
Reduced numerical precision in data storage for weather and climate simulations Peter Düben, Martin Leutbecher, Linus Magnusson European Centre for Medium-Range Weather Forecasts; Contact: peter.dueben@ecmwf.int 1. Introduction: Data storage generates significant cost for weather and climate modelling. If precision in data storage can be reduced with no reduction in information content, we can reduce data volume and store more fields more frequently at the same cost. We investigate how a reduction in precision will influence data quality for weather and climate simulations. We focus on the reduction of data volume for ensemble forecasts. A single operational ensemble forecast at ECMWF generates 11 terabytes of data. 2. GRIB data format: GRIB is a standard data format for output of weather and climate models. Here, real numbers are stored as scaled integers: The maximal and minimal value of a field are identified and the space in between is divided into 2n equidistant numbers where n is the number of bits that is used to store field values (n=16 in standard model output). 3. Climate runs: We have reduced precision for model output of climate simulations and evaluated the impact on several diagnostics. If we half precision to n=8 bits we see only very small significant changes. The evaluation of blocking frequency at reduced precision for IFS model data (cycle 43R1) is presented in the figure below as an example. 5. Two new methods to achieve a stronger reduction in precision in ensemble simulations: Method 1: Reduced Mean. Global fields can vary significantly over the globe. → If we store perturbations from the ensemble mean instead of absolute fields, the max-min distance is greatly reduced. → Precision can be reduced stronger for data storage of ensemble members (50 at ECMWF). However, we need to store the ensemble mean as an additional field. See error plots below. Method 2: Reduced spread. Ensemble spread and predictability can vary significantly over the globe. → We should store data values as normalized perturbations against ensemble spread. → We calculate and store the minimal value (mi) and the ensemble spread (si) at each grid point (two fields) and store a field value vi as: vi‘=(vi−mi)/si. This method links precision of data to predictability. → Rounding errors will be large if ensemble spread is large and model values are uncertain. See errors plots above. 6. Conclusion: To reduce precision in order to reduce data volume for both weather and climate model output appears to be a promising approach. Different model fields should be stored at different precision levels and precision in storage may be reduced as model errors grow with forecast lead time. If the ensemble mean and ensemble standard deviation is used to normalise ensemble data, numerical precision can be reduced much stronger, keeping precision high at the beginning of the forecast where it is needed most. 4. Ensemble weather forecasts: We have reduced precision for model output of ensemble weather forecasts and investigated the influence on Continuous Ranked Probability Scores for different model quantities (Z, T, u, and v) and locations (southern and northern extra-tropics and tropics). Differences are hardly significant if we store data with n=12 bits. If precision is reduced stronger, the minimal precision level that should be used can be different for different locations and model quantities. The impact of a precision reduction is smaller towards the end of the forecast. | poster |
www.didip.eu @DiDip_ERC Digital contributions to a 300 years old methodology: Diplomatics & DH Computer vision approaches for diplomatics: ground truth of a random selection of 1000 charters from the Monasterium.net corpus reformulating layout analysis as an object detection problem instead of the typical image segmentation approach defined a group of visual elements of charters in 11 different classes of interest in our future studies: "Seal", "Writable Area", "Ornament", "Old Text", “Old Note”, "Neww Text", “Neww Other”, “Fold” (i.e. Plica), “Calibration Card”, “No Class” and “Ignore” Daniel Luger, Anguelos Nicolaou, Georg Vogeler, Franziska Decker, Tamás Kovács, Florian Atzenhofer-Baumgartner, Florian Lamminger, Sandy Aoun {forename.surname}@uni-graz.at Preliminary results: We annotated 1000 charters with all these 11 classes within 40 hours and trained an object detection model with similar bounding boxx regressors: between 97% and 70% accuracyy depending on the class at a 50% intersection over union (IoU) threshold Diplomatics = the search for characteristic features of groups of charters, information on their historical context, and for a certain chanceryy practice (“Kanzleimäßigkeit”) The problem: number of 14th and 15th centuryy documents in Central and Southern Europe is beyond the capacityy of a single researcher: e.g. Monasterium.net contains over 600,000 charters from all over Europe (majorlyy Germany, Italyy, Austria, Slovakia, Czech Republic, Hungaryy) Manual detection of charter features for datasets this large is not possible! Screenshot from Monasterium.net as of May 28th 2023 Object detection and other computational methods may revolutionize the study of late medieval charters! possible concrete research questions: ? influences of public notaries on the authentication of charters in the late Middle Ages (Weileder 2019) ? spread of humanistic charter script in the European context and an analysis of the humanistic networks behind it (Luger 2016) References: Luger, Daniel. Humanismus und Humanistische Schrift in der Kanzlei Kaiser Friedrichs III. (1440-1493). Vol. 60. MIÖG Erg. Bd. Wien u.a.: Böhlau, 2016. Weileder, Magdalena. Spätmittelalterliche Notarsurkunden: Prokuratorien, beglaubigte Abschriften und Delegatenurkunden aus bayerischen und österreichischen Beständen. Vol. 18. Archiv für Diplomatik. Beiheft. Köln, Wien: Böhlau, 2019. Screenshot of a charter annotated in FRAT (Fast Rectangle Annotation Tool) | poster |
Antineutrino Energy [MeV] 0 10 20 30 40 50 0 0.5 1 1.5 ] -1 MeV -3 ) [10 e ν → ) µ ( µ ν ( osc P × φ 0.03 0.04 0.05 0.06 Oscillation Probability e ν → ) π ( µ ν (cp) = 0 δ /2 π (cp) = δ π (cp) = δ /2 π (cp) = 3 δ ν / ν CP-Violation Framework Exploiting π Decay at Rest F. Pessina* [PUC (Rio de Janeiro BR)], M. Grassi** [APC/CNRS (Paris FR)] A. Cabrera [APC/CNRS (Paris FR) & LNCA (Chooz FR)], S. Dusini [INFN (Padova IT)], H. Nunokawa [PUC (Rio de Janeiro BR)], F. Suekane [Tohoku U. (Sendai JP)] (Anti)Neutrino Energy [MeV] 0 10 20 30 40 50 ] -1 dN/dE [MeV 0 5 10 15 20 25 30 35 40 3 − 10 × Neutrino energy (MeV) 10 20 30 40 50 60 70 80 90 100 Cross section (10–38 cm2) 10–7 10–6 10–5 10–4 10–3 10–2 10–1 1 10 102 cohNC-p IBD νe-e νx-e νe-e νx-e NC-12C νe-12C νe-12C NC-16O νe-16O νe-16O cohNC-40Ar νe-40Ar νe-40Ar NC-ν-208Pb NC-ν-208Pb νe-208Pb Neutrino Detection Neutrino Interaction Neutrino Production & Oscillation Open Questions in Neutrino Physics Why yet another neutrino CP violation experiment ? Analysis Methods Results: Sensitivity to CP Violation Loading Fraction ) η Number of Interactions at 30 MeV ( 0 0.2 0.4 0.6 0.8 1 osc P × σ × targets N = n Neutrino Antineutrino Loading [g(Pb)/kg(LS)] 10 0.01 20 0.02 50 0.05 100 0.10 200 0.20 500 0.50 Exploit Charged-Current Quasi-Elastic interactions yielding positrons and electrons in the final state Antineutrino: Inverse beta decay (IBD) on liquid scintillator H Neutrino: element with cross-section larger than IBD to be loaded into liquid scintillator. Eg Lead Sensitivity via χ2 analysis Main external uncertainty: sin2(θ23) = 0.5 ± 0.04 [3] ✤Implemented via pull parameter Different exposures studied through a scale factor B ✤Detector efficiency (assumed 100%) scanned via B Near Detector foreseen to investigate ✤Beam-on backgrounds (intrinsic neutrino contamination) ✤Flux normalization through 12C(v,v)12C* reaction ✤Cross-section of the element X loaded into liquid scintillator, normalized to IBD: σ(ν Χ)/σ(v p) ✤If σ(ν Χ) was suppressed (eg. Pb), use 12C charged-current interactions to bridge X and IBD Expected to be leading systematic uncertainty ✤Accounted for through parameter η ✤Scan both η central value and uncertainty References & Acknowledgments Past proposals to investigate CP violation in the neutrino sector aimed at exploiting oscillation-induced distortions in the ve appearance spectrum at multiple baselines, with either a decay-in- flight (HH) [5] or a decay-at-rest [6] neutrino source. The left plot shows how our approach yields better sensitivity in the case of a single-baseline detector, and the expected improvement in the case of a multiple-baseline configuration. Beyond CP Violation Pb allows to tag neutral current interactions thanks to neutron emission ▶︎ Use CC & NC to constrain non-standard v interactions. In case of Supernova burst, clear detection of ve, ve, vx [1] Bolozdynya at al, Arxiv 1211.5199 [2] Scholberg, Annu. Rev. Nucl. Part. Sci. 62 (2012), 81 [3] Capozzi et al, PRD D 95 (2017), 096014 [4] https://europeanspallationsource.se/technology [5] Minakata, Nunokawa PLB 413 (1997), 369 [6] Conrad et al, PRL 104 (2010), 141802 MG acknowledges support by the Marie Curie Research Grants Scheme, grant 707918. FP supported by CnPq and CAPES. *frcs.pessina@aluno.puc-rio.br,**marco.grassi@apc.in2p3.fr ⇡+ ! µ+ + ⌫(⇡) µ µ+ ! e+ + ⌫(µ) e + ¯⌫(µ) µ ⇡−! µ−+ ¯⌫(⇡) µ µ−! e−+ ¯⌫(µ) e + ⌫(µ) µ Accelerated protons hitting target produce pions. Pion decay (τ~28ns) results in mono energetic neutrino emission. Subsequent muon decay (2.2 μs) results in neutrino spectra characterized by 52.8 MeV endpoint. Distance source-detector L=16km (first maximum) Look for appearance of electron (anti)neutrinos from π+ decay chain: %CRVWTGF D[VCTIGV Neutrino: counting analysis (“rate” analysis) Antineutrino: rate & shape analysis v OSCILLATION + ⌫(⇡) µ ¯⌫(µ) µ ⌫(µ) e FLAVOR SOURCE ⌫(⇡) µ ! ⌫e ¯⌫(µ) µ ! ¯⌫e Loading fraction in terms of η = ¯⌫e + p ! e+ + n 208Bi⇤! 208−YBi + Xγ + Yn ⌫e +208Pb ! 208 | poster |
H2020 -731016 The AENEAS (Advanced European Network of E-infrastructures for Astronomy with the SKA) project has been funded in the Horizon 2020 Work Programme call “Research and Innovation Actions for International Co-operation on high-end e-infrastructure requirements” supporting the Square Kilometre Array (SKA). The SKA is an ambitious project to construct the world’s largest radio telescope and enable transformational science and discoveries impossible with current facilities. Built over two sites in Australia and Africa, it will, when complete, provide over a million square metres of collecting area through many thousands of connected radio antennas. The SKA is currently foreseen to be constructed in two phases. By adopting a phased rollout, more developed technologies will be utilized early on in the project to secure the first wave of scientific discoveries at the earliest opportunity and then upgraded with new technology currently under development during the second phase. Together with other countries in the world, European member states are leading partners in the construction. The scientific potential of the forthcoming SKA radio telescope is simply unprecedented and represents one of the highest priorities for the international scientific community in the coming decade. By the same token, the large scale, rate, and complexity of data the SKA will generate present challenges in data management, computing, and networking that are similarly world-leading. Like the SKA itself, a coordinated, global effort will be required to solve these challenges and fully realize the ground-breaking scientific potential of the project. The next few years will be crucial in preparing to support this first SKA science. Based on current projections, it is expected to produce an archive of standard data products with a growth rate on the order of 50—300 petabytes per year. Although the challenges associated with populating and maintaining the SKA science archive are already impressive, these data products actually represent only the first part of the full science extraction chain. Further processing and subsequent science extraction by the community will require a significant research infrastructure providing capacity in networking, storage, computing, and expertise. The AENEAS project represents an opportunity to pursue the design, deployment, and operation of the necessary research infrastructure for SKA science at a European level and in close coordination with the SKA project, the host countries, and other international partners. Ultimately, our ambition is to ensure the astronomy community has the resources it will need to achieve the truly transformational science potential of the SKA. The SKA has been widely identified as one of the major “Big Data” challenges for the next decade. The technical challenges in computing, storage, networking, and analytics required to deploy a research infrastructure capable of supporting European SKA science are also attractive to the IT community, and have much wider applicability both within an academic but also commercial context. A distributed and federated European SRC, therefore, can provide a platform for a European and nationally focused partnership with industry for the continued development of these core technologies and hence a clear route to delivering impact and return. The ultimate objective of the AENEAS project is to develop a concept and design for a distributed, federated European Science Data Centre (ESDC) to support the astronomical community in achieving the scientific goals of the SKA. This design must include the functionality required by the scientific community to enable the extraction of SKA science and integrate the necessary underlying infrastructure not currently provided as part of the SKA Observatory to support that extraction. Taken all together, the European contribution to the SKA design and construction phase represents a large fraction of the total project, and th | poster |
Understanding the Dominance Hierarchy of North American Feeder Birds Eliot T Miller David N. Bonter Charles Eldermire Benjamin G. Freeman Emma I. Greig Luke J. Harmon Wesley M. Hochachka Unlike many organisms, for which competition must be inferred, birds sometimes compete in dramatic, readily quantified ways. Birds at feeders are a good example. * Are the outcomes of these interspecific aggressions predictable? * Can feeder birds be put into a linear dominace hierarchy? * What predicts dominace between these species? ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● Merlin Black Vulture Black−billed Magpie Northwestern Crow Pileated Woodpecker Boat−tailed Grackle Yellow−bellied Sapsucker Western Scrub−Jay American Crow Turkey Vulture Mallard Ring−necked Pheasant Fox Sparrow Eurasian Collared−Dove Evening Grosbeak Band−tailed Pigeon Palm Warbler Red Crossbill Gray−crowned Rosy−Finch Canyon Towhee Varied Thrush Black−crested Titmouse Eastern Phoebe Oak Titmouse Northern Mockingbird Common Grackle Red−bellied Woodpecker Northern Flicker Red−headed Woodpecker European Starling Blue Jay Hairy Woodpecker Red−winged Blackbird American Robin Baltimore Oriole Western Tanager yaJ s'relletS Brown−headed Cowbird Eastern Towhee Gray Catbird Mourning Dove Pine Grosbeak Northern Cardinal Eastern Bluebird White−throated Sparrow Song Sparrow Downy Woodpecker White−crowned Sparrow House Sparrow Yellow−rumped Warbler Spotted Towhee House Finch Chipping Sparrow White−breasted Nuthatch Carolina Wren Red−breasted Nuthatch Pine Warbler Dark−eyed Junco Pine Siskin Purple Finch American Tree Sparrow American Goldfinch Common Redpoll Tufted Titmouse Bushtit Black−capped Chickadee Carolina Chickadee Lesser Goldfinch Chestnut−backed Chickadee White−winged Dove Brown Thrasher Golden−crowned Sparrow California Towhee Swamp Sparrow Orange−crowned Warbler Carolina:Black−capped Chickadee Brown Creeper Mountain Chickadee Ruby−crowned Kinglet hcniF s'nissa C Brown−headed Nuthatch Boreal Chickadee Hermit Thrush Sharp−tailed Grouse Wood Duck Last year we harnessed the power of citizen scientists, participants in Project FeederWatch, to address these questions. This pilot effort, run externally, still received over 2,000 submissions. This coming season the project will be integrated directly into FeederWatch, and we anticipate much greater participation. Find out more at http:// eliotmiller.weebly.com/feederwatch-interactions The vast majority (99%) of interactions between three species are transitive. However, there are some notable three-species intransitive (cyclic) relationships, and a number of larger cycles. This makes assigning species to a linear dominance hierarchy somewhat difficult. Still, there are few instances where inferred subordinate species displaced inferred dominant species (red lines to right). Much of the variance (~35%) in rank is explained by body mass, with some notable phylogenetic influences: woodpeckers are more dominant than expected based on body mass, while parids are less dominant than expected. Downy Woodpecker White-breasted Nuthatch Red-breasted Nuthatch Example of a cyclic (intransitive) triad Email: eliot.isaac@gmail.com Twitter: @EliotITMiller House Sparrow Blue Jay Downy Woodpecker European Starling Northern Cardinal House Finch Dark-eyed Junco American Goldfinch Mallard Ring-necked Pheasant Tufted Titmouse Common Grackle Red-winged Blackbird Mourning Dove Frequency of interaction Rare Frequent Aggressive interactions may shape species' distributions. Can we predict the direction of these interactions? Sharp−tailed Grouse Ring−necked Pheasant Mallard Wood Duck Merlin Eastern Phoebe Western Scrub−Jay Blue Jay yaJ s'relletS American Crow Northwestern Crow Black−billed Magpie Oak Titmouse Tufted Titmouse Black−crested Titmouse Carolina Chickadee Black−capped Chickadee Carolina:Black−capped Chickadee Mountain C | poster |
New Research Opportunities by Open Data Open Source GIS meets the DWD Open Data Portal Dr. Peter Löwe, DIW Berlin (ploewe@diw.de) Mario Hafer, DWD (mario.hafer@dwd.de) • INSPIRE (Infrastructure for Spatial Information in the European Community) is an EU initiative to establish an infrastructure for spatial information in Europe to make spatial information more accessible and interoperable for a wide range of purposes supporting sustainable development. • In parallel, the number of freely available geospatial open source software tools to derive information from spatial data sources continues to grow. • The combination of these two developments has created a critical mass of research opportunities for (citizen) scientists within and beyond Europe. Deutscher Wetterdienst (DWD) is the German Meteorological Service based in Offenbach am Main. Basic charges are to monitor weather and meteorological conditions across Germany and to provide weather services for the general public and for nautical, aviation, agricultural and hydrological purposes. It is governed by the Federal Ministry of Transport and Digital Infrastructure. Principal tasks include warning on weather-related hazards as well as monitoring and accessing climate variability and trends affecting Germany. DWD operates its own numerical weather prediction model suite on its supercomputer and a network of 17 C-Band weather radars for reliable weather forecasts. DWD also manages the national climate archive and one of the largest libraries dedicated to weather and climate worldwide. SELECTED REFERENCES • Metereological data is a valuable ressource for near-real time and retrospective analysis • Measuring, archiving, provision and analysis of streams of metereological data, which continue to grow in volume, variety and velocity, require reliable digital infrastructures. • European initiatives ensure open access to publicly funded geospatial data for citizens, science and education. • Open source software tools opens up new opportunities for innovation in science, education and commerce. • 4D Data Visualisation and Quality Control: https://doi.org/10.5281/zenodo.1422359 • SAWS MaxCAPPI / CFAD video: DOI:10.5281/zenodo.1418432 • SAWS CFADT video: DOI:10.5281/zenodo.1288304 • SAWS Space Tine Cube video: DOI:10.5281/zenodo.1415411 • Methoden der Künstlichen Intelligenz in Radarmeteorologie und Bodenerosionsforschung (urn:nbn:de:bvb:20-opus-7594) • DISSIX: DOI:10.5281/zenodo.1164724 Radar-based Precipitation Climatology of DWD: • 10.5676/DWD/RADKLIM_RW_V2016.003 (gauge-adjusted one-hour precipitation sum) • 10.5676/DWD/RADKLIM_RW_V2017.002 (gauge-adjusted one-hour precipitation sum) • 10.5676/DWD/RADKLIM_YW_V2017.002 (quasi gauge-adjusted five-minute precipitation rate) Das DIW Berlin ist Mitglied der www.diw.de | Oktober 2018 MOTIVATION CONCLUSIONS Deutscher Wetterdienst New Opportunities Stakeholders The German Institute for Economic Research (Deutsches Institut für Wirtschaftsforschung) or more commonly DIW Berlin is one of the leading economic research institutes in Germany. It is an independent, non-profit academic institution which is involved in basic research and policy advice. DIW Berlin presents its research results in science journals, within the scope of national and international scientific events as well as at workshops, symposia and colloquia. Current economic and structural data, forecasts and advice as well as services in the area of quantitative economics are provided to decision makers in economics and policy and the broad public. DIW Berlin endues a target group specific range of publications, events and data sources. DIW is committed to the FAIR (Findable, Accessible, Interoperable, Reusable) paradigm to enable Open Science and is a signatory of the Enabling FAIR Data commitment statement. The Open Source Geospatial Foundation (OSGeo) is a non-profit non- governmental organization whose mission is to support and promote the collaborative development of open ge | poster |
Medienbruchfreie Digitalisierung: Vom Gesetzestext zur digitalisierten Leistung in der öffentlichen Verwaltung HERAUSFORDERUNGEN BEITRÄGE ANSATZ Prof. Dr. Birgitta König-Ries, Universität Jena Dr. Frank Löffler, Universität Jena Marianne Mauch, Universität Jena Leila Feddoul, Universität Jena Sarah T. Bachinger, Universität Jena Max Raupach, Universität Jena Hannes Legner, Universität Jena Suresh Kumar Bonagiri, Universität Jena Robin Erd, Universität Jena Friedrich Tydecks, Universität Jena Balaramakrishna Paritala, Universität Jena Denys Forshayt, Universität Jena Norman Klewer, Universität Jena Pirmin Karg, Universität Jena Philipp Bornheimer, Universität Jena Daniela Erhardt, Stadtverwaltung Jena Sebastian Apel, Stadtverwaltung Jena Dr. Sirko Schindler, DLR e.V. Dr. Clemens Alexander Brust, DLR e.V. Tim Fritzsche, DLR e.V. Dr. Felicitas Löffler, Thüringer Finanzministerium Prof. Dr. Sina Zarrieß, Universität Bielefeld Clara Lachenmaier, Universität Bielefeld Jörg Schröder, BFPI GmbH Prof. Dr. Antje Dietrich, Hochschule Kehl Dr. Naouel Karam, InfAI Infinity GmbH Stephan Löbel, Stein Hardenberg Institut Dr. Tilo Wend, betterlaw Knowledge Tools Automation GmbH Kontakt: Marianne Mauch Friedrich-Schiller-Universität Jena Institut für Informatik Leutragraben 1, Raum 18N03/04 07743 Jena Schreiben Sie uns unter: opendva@uni-jena.de Website Twitter E-Mail Arbeitsgruppe offenes Design digitaler Verwaltungsarchitekturen (openDVA) Gefördert durch:openDVA VISION Fehlender Zugang zu notwendigen Informationen Hochkomplexe föderale IT-Landschaft Divergierende Interessen von Dienstleistern Mangelnde Flexibilität in Verwaltungsleistungen Dokumentation / Modellierung von Wissen zu Normen, Dienste und zuständigen Behörden Umsetzung von Verwaltungsleistungen (jenArbeit) Erweiterung des FIM-Standards / Referenzarchitektur Rechtstexte als Basis für Verwaltungsprozesse Identifizierung von Prozesselementen (Akteure, Aktivitäten, usw.) Annotationsunterstützung durch NLP Ziel: Formale Beschreibung von Verwaltungsprozesse Verschiedene Datenaustauschformate wie XOEV, FIM-Artefakte oder E-Akte Formale Beschreibungen von FIM (Leistung, Prozess, Datenfelder) und Entscheidungen (Rule Mapping) Ziel: Maschinenlesbare Artifakte als Basis für semantische Beschreibungen Wiederverwendbare Basisdienste wie Authentifizierung und Bezahlung Nahtlose Integration mit anderen beteiligten Systemen Ziel: Medienbruchfreie Digitalisierung und bürgerfreundliche, intelligente Automatisierung Rechtstextanalyse Formale Beschreibung Digitale Verwaltungsleistung Analyse Low- / No-Code Gemeinsame, verknüpfte Terminologien Ontologie GerPS-onto für Beschreibung von Verwaltungsprozessen (Verknüpfung bestehender Terminologien (E-Gov Core Vocabularies [1] und BBO [2]) Ziel: semantische Interoperabilität als Basis für Automatisierung Wissensgraphen Softwareentwicklung für Domain- Experten zur Erstellung eigener Leistungen Beseitigen von Kommunikationsengpässen Ziel: modularer, intelligenter Baukasten zur Erstellung von Leistungen basierend auf Datenschutz, Sicherheit und Qualität Low-Code / No-Code [1] https://joinup.ec.europa.eu/collection/semantic-interoperability-community-semic/solution/e-government-core-vocabularies [2] Annane, A. et al.: BBO: BPMN 2.0 based ontology for business process representation. In: ECKM 2019. volume 1, pp. 49–59, 2019 https://github.com/fusion- jena/GerPS-onto Unterstützung von fuzzy Suchanfragen, die über exakte Übereinstimmungen hinausgehen Strukturierte Abfragen zur Einschränkung der Suche, z.B. auf Akteure in bestimmten Rollen Semantische Suche Wenn sich Gesetzestexte ändern, was muss angepasst werden (Prozess, …)? Ermöglichung von Probeläufen während des Gesetzgebungsverfahrens bevor Änderungen in Kraft treten Änderungsmanagement Erstellung zielgruppenspezifischer Versionen, z.B. für Laien oder in einfacher Sprache Prozesse für ein breiteres Publikum zugänglich und verständlich gestalten Textgenerierung | poster |
DAGA 2014 40TH GERMAN ANNUAL CONFERENCE ON ACOUSTICS Oldenburg, Germany March 10–14, 2014 How Microtonal is a Well-Tuned Concert Grand Piano? Timour Klouche Staatliches Institut für Musikforschung PK, Berlin, Germany Introduction The core question of this paper is how accurate the tun- ing of a well-tuned concert grand piano is. The underly- ing experiment is a direct extension of previous studies [1] [2] centering on methodological issues concerning validating tuning accuracy [1], and measuring micro- tonal accuracy of virtual instruments respectively [2]. After first presenting a series of measurements, we focus on exemplary details and relate the final outcome to that of the virtual piano presented at DAGA 2013. A more de- tailed version of the paper will be available online [3]. Setup and Methods The minimization of external influences to the mea- surements has been given high priority throughout the inception of our microtonal validation series [1]. We thus applied the very same, already validated and tested ex- perimental setup. That in turn makes a direct compar- ison with last years’ virtual piano (Pianoteq software synthesizer) tuning measurements possible. The inter- ested reader is directed to the publication [2] for details of the setup incl. all measurement and preprocessing parameters. Following is a very brief summary of the steps involved: The complete pitch gamut of a Steinway D concert grand piano is recorded directly after the tun- ing process preparing public concerts in the Curt-Sachs Saal of the Staatliches Institut für Musikforschung. Each recording consists of 88 piano pitches in the way that each key is depressed for 6s followed by 6s silence, cap- tured by ORTF condenser microphones. Subsequently the sound file (2 channel 192 kHz, 24 bit) is monoized, segmented with a MATAB rms-dependent script and analyzed via Praat. The fundamental frequency is calcu- lated with the F0 autocorrelation function of Praat (for all details see [2]). Two aspect are changed in comparison to the setup used in the last publication: Firstly, we had to include a recording chain to the measuring setup prior to the analyzing procedure, and secondly, a human player is added. How both factors are influencing the results will be analyzed in later experiments as are perceptive and cognitive implications. Here we focus deliberately on the signal description layer with measuring the funda- mental frequencies of piano tones. Results Results A: Measurements of 16 fresh tunings The analysis of the series of measurements (n=16) is de- picted in Fig. 1 and 2. Interestingly, outliers (up to roughly 3000 cents) are not everywhere and seem to be not equal- ly distributed (Fig. 1). Remarkable areas are the smooth re- gions around A4 and A5-A6 and the downturn from A6 on associated with large ranges but within also a zone with notably small measuring ranges. The downturn area is possibly indicating a measuring- or stimuli related artifact leading to a result approx. one oc- tave (but notably less than; cf. Results D) below the ex- pectancy value. Figure 2 depicts a zoomed window illus- trating how most values average around the expectancy value within 10 cents deviation with outliers not exceed- ing 40 cents in the mid frequencies. Results B: Selection of the best-fit piano tuning The single tuning with statistically least deviation to the expectancy had been chosen for further examination and later reprocessing (see Results C). Figure 3 shows a smooth fluctuation around 5 cents (indicating an offset) with out- lier areas below A1 and over A6. Intra-note ranges are de- picted in Fig. 4 that exhibits a similar picture with fluctua- tions around 5 cents and respective outliers. The ranges’ outliers are excessive only in the lows, likely indicating more plausible measuring errors in that area and a stimuli related problem in the highs (with below 30 cents ranges). Results C: Data reprocessing & comparison with a virtual piano Three aspects were c | poster |
> AUSBAU SCHULUNGSANGEBOT Fachspezifische Forschungs- datenrepositorien 1 repräsentatives Repositorium pro Bereich der TUD Schulungsreihe auf der Grundstruktur des Prototyp Workshops Veröffentlichung als OER auf Zenodo Multidisziplinär: Prototyp Zenodo Workshop Wissensbasis FDM für weitere Schulungen nachnutzbar repositorienspezifischer Aufbauteil veränderbar Mathematik und Naturwissenschaften: 4TU? Spektrum: Naturwissenschaften, Ingenieurwissenschaften und Design Core Trust Seal Geistes– und Sozialwissenschaften: GESIS forschungsbasierte Infrastrukturein- richtung für Sozialwissenschaften Core Trust Seal Ingenieurwissenschaften: NOMAD? Fokus: Materialwissenschaften von FAIRmat entwickelt Bau und Umwelt: PANGAEA Fokus: Geodaten Core Trust Seal Medizin: German Central Health Study Hub Spektrum: klinische, Public Health, epidemiologische Forschung Metadatenveröffentlichung mit Information zum Datenzugang Kontakt: forschungsdaten@slub-dresden.de | janna.little@slub-dresden.de | poster |
Development of bioprinted osteochondral tissue: an in-vitro model for drug discovery Shahrbanoo Jahangir1, Jana Vecstaudža2, Elena Canciani3, Jānis Ločs2, 4, Mauro Alini1, *, Tiziano Serra1 1- AO Research Institute Davos, Davos, Switzerland 2- Rudolfs Cimdins Riga Biomaterials Innovations and Development Centre of RTU, Institute of Genera Chemical Engineering, Faculty of Materials Science and Applied Chemistry, Riga Technical University, Pulka Street 3, LV-1007, Riga, Latvia 3- Laboratory of Immunomics, Department of Health Sciences, center of translational research on Autoimmune & Allergic Diseases, CAAD. University of Eastern Piedmont, UPO. Corso Trieste 15/A. 28100 Novara- Italy 4- Baltic Biomaterials Centre of Excellence, Headquarters at Riga Technical University, Riga, Latvia Introduction: Osteochondral (OC) disorders like osteoarthritis (OA) and rheumatoid arthritis (RA) damage the joint's cartilage and subchondral bone. Their treatment remains a significant challenge for both researchers and orthopedics. In vitro models of OC tissue have become an essential tool to help investigate pathogenesis, develop drug screening, and test potential therapeutic approaches. This study aims to create a bio-printed OC construct recapitulating the bone and cartilage compartment as drugs testing platforms. Methodology: Two different hydrogels including a blend composed of gelatin methacrylate (GelMA) with nanosized hydroxyapatite (nHA) and tyramine-modified hyaluronic acid (THA) were selected for the bioprinting of bone and cartilage tissue mimics. The composition of GelMA hydrogel (10% w/v) with different concentrations of nHA (1-10% w/v) and THA with concentrations of 2.5-5% w/v were characterized by rheology and their cytotoxicity was assessed via live-dead assay. Later, the pre-differentiated osteoblast and endothelial cells were encapsulated into GelMA-nHA and micropellet chondrocytes into THA hydrogels for bioprinting osteochondral construct. After 2 weeks of culturing, the successful generation of OC tissue was confirmed by real-time RT-PCR and histology. Results: The storage modulus (G') of all GelMA/nHA hydrogels was significantly higher than GelMA, however, there was no significant difference in G' values for the GelMA/nHA as a function of added nHA. Due to the know temperature sensitivity of GelMA, a rheological temperature sweep and series of printing tests were performed to establish a suitable printing temperature, which was confirmed to be 20°C, independent of the addition of nHA. Calcein- AM (Ca-AM) and Ethidium Homodimer-1 (EthD-1) staining for GelMA (10% w/v) with three | poster |
WHY DOES ENGLISH NEED TO BE BOTHERING WHILE ROMANCE JUST BOTHERS? Eugenia Mangialavori Rasia1 and Josep Ausensi2 1CONICET & 2Universitat Pompeu Fabra WHY DOES ENGLISH NEED TO BE BOTHERING WHILE ROMANCE JUST BOTHERS? Eugenia Mangialavori Rasia1 and Josep Ausensi2 1CONICET & 2Universitat Pompeu Fabra Introduction • We focus on Intransitive Causatives (ICs), an underexplored argument structure realization in verbs entering causative alternation, with key implications for argument structure and verb formation/derivation. We focus on the asymmetry between English (1) and Romance (2). (1) a. Smoking kills. b. Bleach disinfects. c. Alcohol dehydrates. d. Rice constipates. e. Shaving creams irritate. f. Sunlight oxidizes and discolors. g. Normal dryers wrinkle. (2) a. Fumar mata. b. La lejía desinfecta. c. El alcohol deshidrata. d. El arroz estriñe. e. Las cremas de afeitar irritan. f. La luz solar oxida y destiñe. g. Las secadoras arrugan. • ICs challenge major claims on argument structure and causative alternations: 1. The internal argument defined a constant constituent in the causative alternation (Haley & Keyser 2002) 2. The prediction that a unique argument in causative alternating verbs will be interpreted as undergoer by default (Levin & Rappaport Hovav 2005). Conversely, ICs show defective cause(r) reading. Aspect and semantics of ICs • (a) ICs cannot appear in perception reports, be located in space (3) or license habitual readings (4). (3) a.#John saw smoking kill. (cf. I saw John kill Tom) b.#Shaving creams irritate in the bathroom. (4) a. Alcohol (#regularly) dehydrates. (cf. John regularly kills ani- mals) b. Smoking (#regularly) kills. • They are odd in contexts forcing eventive readings (5). Modals gen- erate epistemic (not deontic) readings (6). This pattern is the one ex- pected for states (Maienborn 2005, Rothmayr 2007). (5) a.#What the dryer did was wrinkle. (cf. What John did was kill animals) b.#What happened was that rice constipated. (6) a. Smoking must kill (OK It probably has property x | #It is under obligation to kill) b. John must kill Tom (#He probably has property x | OK He is under obligation to kill) • (b) ICs are similar to middles in that they are restricted to generic tenses (*Smoking killed/This vase broke easily). Both constructions pattern sta- tively, and like dispositional generics. • They do not entail a deontic reading, but report a property of the sub- ject (Lekakou 2015). ICs are thus true in virtue of properties inherent to the subject • ICs contrast with dispositional habituals that “assert the existence of a pattern of regularly recurring events” (Krifka et al. 1995) (true insofar as there were actual helping events in the past, e.g., John helps homeless people). • ICs crucially differ from middles in that the sole DP is not internal but external: hence, the property is not attributed to an undergoer (theme), but to a cause. • (d) Genericity is a property shared with another dyadic/monadic argu- ment structure alternation (Unexpressed/Null Object alternations, Levin 1993) (8): PROPERTY-OF-AGENT ALTERNATION. (7) a. This dog bites (#but hasn’t bitten anybody yet). b. Stand back! This horse kicks (#but hasn’t kicked anybody yet). • Yet, ICs are distinct in verb type (activity/manner verbs in (8) vs. re- sult verbs in ICs) and interpretive and selectional restrictions on the subject (animate/volitional actor in (8) vs. inanimate causer in ICs). Syntax of ICs Unlike Property-of-Agent Alternation (7), ICs are not null-object con- structions (NO). • ICs do not allow null-object-oriented depictive predication, which is OK if arbitrary implicit arguments are present (cf. Il dottore visita [ ] nudi ‘The doctor visits [ ] naked’ (Rizzi 1996)). (8) a. *Smoking kills dead/depressed. b. John cooks healthy. c. John buys cheap. • ICs do not allow null object quantification either (e.g. bare molti, Ital- ian) (9) a. *Smoking kills a lot. b. John eats a lot. • Ne-cliticization and inchoative/passive morphol | poster |
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