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Which of the following opioid analgesic acts primarily through K opioid receptors?
(Ref: KDT 6/e p464, 465) Pentazocine can cause dysphoric reactions (hallucinations) by stimulating the K receptors.
1
Pentazocine
Methadone
Buprenorphine
Pethidine
Anatomy
Other topics and Adverse effects
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single
Kappa statistics is used to measure
null
1
Inter examiner validity
Correlation
Regression
Proportion
Dental
null
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single
Which of the following is not a component of Glasgow Coma Scale?
Ans. is 'c' i.e. pupil size
3
Eye opening
Motor response
Pupil size
Verbal response
Surgery
null
8068717f-962e-4012-9a31-263500b618e0
single
Form the normal bacterial flora of the conjunctiva
Ans. Corynebacterium xerosis
1
Corynebacterium xerosis
E. Coli
Streptococci
All of the above
Ophthalmology
null
a2841be9-4b54-4065-9373-98b9919af87b
multi
Hypoceruloplasminimia is associated with which abnormality?
(A) Menkes disease # Deficiency or Lower-than-normal ceruloplasmin levels may indicate the following:> Wilson disease copper storage disease)> Menkes disease (Menkes kinky hair syndrome) (rare - UK incidence 1/100,000)> Overdose of Vitamin C> Copper deficiency> Aceruloplasminemia> Excess or Greater-than-normal cerulopl...
1
Menkes disease
Alzheimer's disease
Schizophrenia
Obsessive-compulsive disorder
Psychiatry
Miscellaneous
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single
According to triage patient having visible bleeding should be treated in:
null
1
Emergency.
Delayed.
Minimal treatment.
No treatment.
Surgery
null
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Apart from plasmodium, which of the following can infect RBCs in "ring forms"?
Ans. a (Babesia microti). (Ref. Harrison's, Principles of Internal Medicine, 16th ed., pg1232)Babesiosis (B. microti)# Babesiosis is a worldwide protozoan disease of animals that is transmitted by ticks; humans are infected incidentally and initially develop a nonspecific febrile illness that can lead to hemolytic anem...
1
Babesia microti
Tyrpanosomas
Schistosomia
Microfilaria
Microbiology
Parasitology
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Following clostridia are saccharolytic except ?
Ans. is 'b' i.e., Sporogenes . Clostridia may break down carbohydrate for energy (sacchrolytic) or break down protein for energy (proteolytic) or both. Different clostridia have different pattern :- . Both proteolytic and saccharolytic - Predominating proteolytic --> CL sporogenes, Cl botulinum A .B.F., Cl. bifermentan...
2
Welchii
Sporogenes
Septicum
Oedematiens
Microbiology
null
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multi
A 32-year-old primi gravida presents with DVT. There is history of 2 episodes of DVT in the past and was diagnosed to have antiphospoholipid antibody. Next step in management is:
Ans: B (Aspirin and heparin) Ref: Maternal-Fetal Medicine edited by Mary E. D'Alton. pg: 10-14 and DC Dutta's Textbook of Obstetrics. 7th edition, pg: 343 Explanation: "ACOG 2005 guidelines recommends low dos aspirin t5-80 mg orally per day along with unfractionated heparin 5000 unit subcutaneously twice daily. The the...
2
Aspirin alone
Aspirin and heparin
LMWH
Warfarin for 6 months
Unknown
null
a3136ec5-a8f7-41e3-9ea0-943e066f511a
multi
Iridocorneal endothelial syndrome is associated with –
Iridocorneal endothelial (ICE) syndrome is characterized by abnormal corneal endothelium which causes :- Iris atrophy, Secondary angle closure glaucoma in association with characteristic peripheral anterior synechiae, Corneal edema. Option 'c' may cause confusion here. You should keep in mind that in iridocorneal endot...
1
Progressive atrophy of iris stroma
Bilateral stromal edema of iris & cornea
Deposition of collagen in Descemet's membrane
Deposition of glycosaminoglycan in Descemet's membrane
Ophthalmology
null
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An elderly man complains of ear pain. During evaluation, the physician asks if the patient has tinnitus. What is tinnitus?
Tinnitus is the perception of abnormal noise in the ear or head. It is usually attributed to a sensory loss; pulsatile tinnitus occurs with conductive hearing loss and is due to carotid pulsations becoming more apparent.
1
A subjective sensation of noise in the head
A complication of chronic metal ingestion
An audible cardiac murmur
Dizziness with sounds
Surgery
Nervous System
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single
A 6 year old child with IQ of 50. Which of the following can the child do?
IQ is defined by as the mental age divided by the chronological age multiplied by 100. In this case, a child of 6 years of age with an IQ of 50%, means that his mental age is that of a 3 year old child. At 3 years of age, a child can identify two colours. Ref: Essential paediatrics by OP Ghai, 6th edition, Page 543.
1
Identify colours
Read a sentence
Ride a bicycle
Copy a triangle
Pediatrics
null
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single
In fracture surgical neck of humerus, the following nerve injury is common:
A i.e. Axillary
1
Axillary
Radial
Ulnar
Median
Surgery
null
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single
Not an indication for blood transfusion
Indications for Blood Transfusion  To correct anemia due to blood loss and to combat postpartum hemorrhage Patient with severe anemia seen in later months of pregnancy (beyond 36 weeks) Refractory anemia: Anemia not responding to either oral or parenteral therapy in spite of correct treatment Associated infection
1
Moderate anemia at 24-30 weeks
Severe anemia at 36 weeks
Blood loss anemia
Refractory anemia
Gynaecology & Obstetrics
null
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Trans-placental spread is least associated with?
HSV infection may be acquired in utero, during the birth process, or during the neonatal period. Intrauterine and postpartum infections occur infrequently. Most cases of neonatal herpes result from maternal infection and transmission, usually during passage through a contaminated infected birth canal of a mother with ...
1
HSV
Rubella
HBV
HIV
Pediatrics
null
6025f06f-f128-461f-a138-a489777e81a3
single
Ovum is released due to
Ovulation-the discharge of a secondary oocyte from the Graafian follicle; in an adult woman, this normally occurs at intervals of about28 days and alternates between the two ovaries. As a rule, only one secondary oocyte is produced, but occasionally ovulation produces two or more; if more than one subsequently become f...
2
FSH
LH
Prolactin
HCG
Physiology
Endocrinology
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Sholy after the administration of an inhalational anesthetic and succinylcholine for intubation prior to an elective inguinal hernia repair in a 10-year-old boy, he becomes markedly febrile, displays a tachycardia of 160, and his urine changes color to a dark red. Which of the following is the most appropriate treatmen...
The cause of malignant hypehermia is unknown, but it is associated with inhalational anesthetic agents and succinylcholine. It may develop in an otherwise healthy person who has tolerated previous surgery without incident. It should be suspected in the presence of a history of unexplained fever, muscle or connective ti...
4
Complete the procedure but pretreat with dantrolene prior to future elective surgery.
Administer inhalational anesthetic agents.
Administer succinylcholine
Hyperventilate with 100% O2 .
Anaesthesia
Miscellaneous
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A gastric biopsy is performed on a patient with suspected graft-versus-host disease following bone marrow transplantation. The biopsy demonstrates many isolated dying epithelial cells in crypts showing fragmented, hyperchromatic nuclei and small discrete blebs containing both cytoplasm and nuclear fragments. The biopsy...
The changes described are those of apoptosis, which is a form of programmed cell death. Apoptosis can be seen in a variety of settings. In this case, it is occurring in the context of graft-versus-host disease, which is mediated by CD8+ and CD4+ cells. Apoptosis also occurs during embryogenesis, during hormone-dependen...
1
Apoptosis
Caseous necrosis
Coagulative necrosis
Gangrenous necrosis
Pathology
null
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multi
Varenicline is used in
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor paial agonist. Specifically, varenicline is a paial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor Ref Davidson 23rd edition pg 578
4
Pulmonary hemosiderosis
Sleep apnea
Anti-trypsin deficiency
Nicotine dependency
Medicine
Respiratory system
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Cyst seen in vagina are all except:
Ans: A (Nebothian cyst) Ref: Shows Textbook of Gynecology 15th ed pg 136Explanation:VAGINAL CYSTSVaginal cysts are rare and are located more commonly in anterior vaginal wallGartner's cystArises from remnants of mesonephric ductLies in anterolateral aspect of vaginal wallSmall cyst is asymptomaticLarge cyst causes dysp...
1
Nebothian cyst
Gartner's cyst
Bartholin's cyst
Inclusion cyst
Gynaecology & Obstetrics
Miscellaneous (Obs)
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multi
Features of achalsia cardia are all of the following except: March 2009
Ans. C: Rat-tail deformity and filling defect on barium study Dysphagia is the most common presenting symptom in patients with achalasia. The ingestion of either solids or liquids can result in dysphagia. Emotional stress and the ingestion of cold liquids are well-known exacerbating or precipitating factors. 80-90% of ...
3
Regurgitant vomiting
Elongated and dilated esophagus
Rat-tail deformity and filling defect on barium study
Increased difficulty in swallowing
Surgery
null
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A 6 year old girl presents with Recurrent E.coli infection in urine. Ultrasound of abdomen shows Hydroureter and Hydronephrosis. Micturating cysto – urethrogram shows filling defect in urinary bladder. The likely diagnosis is –
IVP in ureterocele usually shows a round filling defect, sometimes large, in the bladder corresponding to the ureterocele, and characteristic finding of duplication of the collecting system (ureteroceles are nearly always associated with ureteral duplication) Ureterocele : Is a cystic dilatation of the terminal ureter...
4
Sacrococcygeal Teratoma
Vesicoureteric Reflux – grade II
Duplication of Ureter
Ureterocele
Pediatrics
null
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Orchidopexy is done in cases of undescended testes at the age of
Ans. is 'a' i.e. Infancy Campbell's Urology writes - "Definitive treatment of an undescended testis should take place between 6 and 12 months of age. Because spontaneous descent occurs in most boys by 3 months of age and uncommonly thereafter, earlier interventions should be considered in order to theoretically prevent...
1
Infancy
1-2 yrs
5 yrs
Puberty
Surgery
Miscellaneous (Testis & Scrotum)
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A 45 year old woman develops abdominal and pelvic discomfo. Physical examination reveals a large mass in the right lower quadrant, which is surgically resected. The mass consists of a large (25 cm) cystic sac containing thick mucinous fluid within a thin wall. On careful inspection, the pathologist finds an area of inc...
Classification of ovarian tumors, like testicular tumors, is based on putative cell of origin. Thus, ovarian tumors can be divided into neoplasms of germ cells,surface epithelium, or stromal origin. Two thirds of all ovarian neoplasms derive from the surface (coelomic) epithelium. These cystic tumors may contain clear ...
1
Borderline mucinous tumor
Mucinous cystadenocarcinoma
Mucinous cystadenoma
Serous cystadenocarcinoma
Gynaecology & Obstetrics
null
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multi
A man is brought to casualty who met with A. He sustained multiple rib fractures with paradoxical movement of chest. Management is
Ventilator suppo with IPPV(intermittent positive pressure ventilation) is the treatment of choice.Assisted ventilation is required for several days until the chest wall stabilises.If ventilator suppo is required for more than 10 days,then tracheostomy is done to prevent laryngeal stenosis which can occur due to prolong...
4
Tracheostomy
Consult cardiothoracic surgeon
Strapping
Intermittent positive pressure ventilation
Surgery
Cardio thoracic surgery
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single
The hookworm thrives on ?
Ans. is 'b' i.e., Plasma Hook worms Ancylostoma duodenale - Old world hookworm Nector americanus - New world hook worm Habitat - Small intestine (Jejunum > duodenum > Ileum) Infective form - Filariform larva Mode of infection - Penetration of skin Plasma forms the main source of nourishment for hookworm, the red blood ...
2
Whole blood
Plasma
Serum
RBC
Microbiology
null
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single
Which of the following penicillins has the best gram negative spectrum?
null
2
Methicillin
Ampicillin
Penicillin V
Cefixime
Pharmacology
null
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single
Eminectomy is done for treatment of:
null
2
TMJ ankylosis
TMJ dislocation
Coronoid fracture
All of the above
Surgery
null
ac331422-2134-43a3-bf9d-60d4c273ec09
multi
Which of the following is a RNA virus?
null
1
Measles virus
Herpes virus
Papaya virus
Adeno virus
Microbiology
null
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single
Following drugs are the first choice in treating patients with candidiasis except-
Ans. is "d' i.e., Caspofungin Choice of drugs for systemic mycosesDiseaseDrugs1st Choice2nd Choice1) Candidiasisoral/vaginal / cutameous deep / invasive AMB/VORIAMB/VORIHRFLU/CAS/POSA2. CryptococcosisAMB/+-5-FCFLU3. HistoplasmosisITR/AMBFLU4. CoccidioidomycosisAMB/FLUITR.'KTZ5. BlastomycosisITR/AMBKTZ/FLU6. Sporotricho...
4
Fluconazole
Nystatin
Amphotericin B
Caspofungin
Pharmacology
Anti-Fungal
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multi
All of the following are anti HIV agents except ?
Ans. is 'b' i.e., Acyclovir
2
Ritonavir
Acyclovir
Didanosine
Zidovudine
Pharmacology
null
3253af62-3b54-465e-a439-105e1ef4ddc8
multi
Which one of the following drugs of abuse is most typically associated with the illustrated complication??
Answer C. CocainePerforation of the nasal septum and palate are well recognized complications of intranasal cocaine use.
3
Ketamine
Heroin
Cocaine
Phencyclidine
Medicine
Drugs
7808cdb3-be99-4d58-8751-dea69c907d35
multi
Most common symptom associated with adult OCD?
(a) Pathological doubt, Ref: Complete review of psychiatry by Dr. Prashant Agrawal, ed.,, 2018, ch- 7, pg. 164 Explanation: Variable % Obsessions (N=200) Contamination 45 Pathological doubt 42 Somatic 36 Need for symmetry 31 Aggressive 28 Sexual 26 Other 13 Multiple obsessions 60 Compulsions (N=200) Checking 63 Washing...
1
Pathological doubt
Need for symmetry
Sexual
Aggressive
Psychiatry
Mood Disorders
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Pralidoxime acts by -
Ans. is 'a' i.e., Reactivating cholinesterase enzyme o Pralidoxime is most commonly used cholinesterase reactivater.OXIMESo Oximes 1 Pralidoxime 2-PAM, obidoxime and diacetyl-monoxime (DAM)J are used in organophosphatepoisoning.o Oximes acts by reactivating cholinesterase enzyme.o Mechanism of actionIn organophosphate ...
1
Reactivating cholinesterase enzyme
Promoting synthesis of cholinesterase
Promoting synthesis of acetylcholine
Direct action on cholinergic receptors
Pharmacology
Cholinergic System
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single
Malignant cells in urine cytology are most commonly seen in
Ans. c (Urothelial carcinoma). (Ref. Harrison's Medicine 17th ed. 555)# Urothelial malignancy classically shows polychronotropism & multicentricity.# In urothelial or transitional carcinoma of renal pelvis or ureter, the examination of urine for malignant cells is positive and even may indicate whether tumor is well or...
3
Renal cell carcinoma
Prostate carcinoma
Urothelial carcinoma
Bladder carcinoma
Surgery
Urinary Tract
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Drug of choice for mushroom poisoning is :
null
1
Atropine.
Solefenacin.
Oxybutynin.
Tolterodine.
Pharmacology
null
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Surya kant is prescribed with first generation antihistaminic. He should be advised to avoid:
Ans. A. Driving motor cycleFirst generation antihistaminic like promethazine, diphenhydramine crosses the blood brain barrier and have higher incidence of sedation. Another property of these drugs is that they show anticholinergic side effects. Due to this patient is asked not to drive any vehicle.
1
Driving motor cycle
Consuming cheese
Physical exercise
All of the above
Pharmacology
Miscellaneous (Pharmacology)
317c6251-f5b1-4b02-8baa-947e91e1d59f
multi
Pivot shift test is positive with
Ans. a (Anterior cruciate ligament tear) (Ref. Adam's orthopedics 11th/pg, 315-325)Knee Joint Injuries1Normal range of motion# Flexion: 135 degrees# Extension: 0 to 10 degrees above horizontal plane2Patellar apprehension test# Evaluates for patella subluxation3Anterior cruciate ligament (ACL) stability tests# Lachman t...
1
Anterior cruciate ligament tear
Posterior cruciate ligament tear
Medial meniscus injury
Lateral meniscus injury
Orthopaedics
Injuries Around the Thigh & Knee
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Antidepressant drug used in nocturnal eneuresis is -
Drugs used in nocturnal enuresis are imipramine and desmopressine.
1
Imipramine
Fluoxetine
Trazdone
Sertaline
Psychiatry
null
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single
A pregnant lady at 32 weeks of gestation presents with a BP of 160/110 mmHg, proteinuria with retinal haemorrhage. What is the definitive treatment of choice in this patient?
This patient is showing features of severe hypeension which is an indication for delivery. Induction of labour is the definitive treatment of choice which is most preferable. In order to prevent the onset of seizures magnesium sulfate prophylaxis should be given. Features of severe pre eclampsia are: BP > 160/110 >- 3 ...
4
Ritodrine
Nifedipine
Magnesium sulphates
Termination of pregnancy
Gynaecology & Obstetrics
null
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Which is not a component of APGAR Score –
null
4
Colour of the body
Muscle tone
Heart rate/minutes
Respiratory rate per minute
Pediatrics
null
cf641071-6dbd-4872-b895-c2a6cacf6688
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Chromosome in which centromere is close to one end which result in short arm being very short is which type of chromosome?
Ans. d (Acrocentric). (Ref. Cell & Molecular Biology by DeRobertis, 7th /pg. 348)CHROMOSOMES# The entire genetic information contained in the genes is packaged in the chromosomes. All the somatic cells of an individual organism contain the same number of chromosomes.# Genes are arranged linearly on the chromosomes and ...
4
Metacentric
Submetacentric
Telocentric
Acrocentic
Anatomy
General
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Which among the following is a mechanism of action of colchicine?
Colchicine is known to suppress many immune functions in the setting of crystal induced ahritis by 1. decreasing neutrophil chemotaxis 2. decreasing neutrophil adhesion 3. decreasing release of multiple inflammatory mediators 4. decreasing phagocytosis of urate crystals by neutrophils. Mechanism: Colchicine binds to tu...
1
Suppression of immunity
Increase in uric acid excretion
Decrease in uric acid synthesis
None of the above
Pharmacology
null
52326d02-8302-4436-be24-ea5a5f44d82b
multi
Bollinger bodies are seen in -
null
3
Chickenpox
Cowpox
Fowlpox
Smallpox
Microbiology
null
870d7455-f9a8-4e98-9576-0886fd889ee7
multi
About Kawasaki disease all are true, EXCEPT:
Suppurative lymphadenopathy
4
Mucocutaneous lesions
Coronary aery is involved
Seen in children
Suppurative lymphadenopathy
Medicine
null
d1869c29-3776-4ff6-85b8-34120edf484b
multi
Which of the following is a L-type calcium channel blocker:
Ans. (d) All of the aboveRef. KDT 6th ed. / 528Types of Calcium Channel Blocker L-Type (long lasting current)T-type (transient current)N-Type (neuronal)Locations and function* Excitation -contraction coupling in cardiac and smooth muscle* SA, A-V node: conductivity* Endocrine cell: Hormone release* Neurons: transmitter...
4
Nifedipines
Amlodipines
Diltiazem
All of the above
Pharmacology
Anti-Hypertensive
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multi
Male to male transmission is seen in -
Robbins basic pathology 9th edition page no 218,Heading=Transmission patterns of single-gene disorders Disorders of autosomal dominant inheritance are manifested in the heterozygous state, so atleast one parent in an index case usually is affected, both males and females are affected, both males and females are affecte...
1
Autosomal dominant diseases
Autosomal recessive
X-linked dominant
Mitochondrial disease
Pathology
General pathology
bafc4838-ff95-4fac-bf18-7522993b43cf
single
Sputum from one patient is disinfected immediately following expectoration, this is known as:
Ans: a (Concurrent) Ref: Park, 19th ed, p. 108Sterilization is the process of destroying all life including spores.Disinfection- is the killing of infectious agents outside the body by direct exposure to chemical or physical agents.Types of disinfection:a) Concurrent disinfection- It is the application of disinfective ...
1
Concurrent
Pre current
Recurrent
Terminal
Social & Preventive Medicine
Communicable Diseases
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single
'Sequestration' is best defined as:
Ans. B. A piece of dead bone surrounded by infected tissue (Ref. Maheshwari ortho 3rd/pg.l60)Maheshwari orthopaedics 3rd/pg. 160...."Sequestrum is a piece of dead bone, surrounded by infected granulation tissue trying to 'eat' the Sequestrum away"CHRONIC OSTEOMYELITISPresents in 3 forms:A. Chronic osteomyelitis seconda...
2
A piece of dead bone
A piece of dead bone surrounded by infected tissue
A piece of bone with poor vascularity
None of the above
Orthopaedics
Infection of Bones & Joints
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multi
Dose of Rabies immunoglobulin is?
Anti rabies serum is given in class III bites (Single or multiple transdermal bites or scratches, licks on broken skin, Contamination of mucous membranes with aalvia, exposure to bats) It is found to prolong the incubation period. Passive immunization in rabies may be given by : Horse Anti-rabies serum : 40 IU/kg body ...
3
10 IU/Kg body weight
15 IU/kg body weight
20 IU/kg body weight
25 IU/kg body weight
Unknown
null
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single
Progressive cognitive impairment is Alzheimer's disease is characterized by
Memory impairment is typically an early and prominent feature in dementia, especially in dementias involving the coex, such as dementia of the Alzheimer's type. Early in the course of dementia, memory impairment is mild and usually most marked for recent events. As the course of dementia progresses, memory impairment b...
2
Nominal aphasia
Recent memory loss
No behavioral abnormalities
All
Psychiatry
Organic mental disorders
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multi
Mesothelioma is most commonly caused by?
Ans. (a) AsbestosisRef: Harrison 19th ed. /1689* Working with asbestos is the most common risk factor for mesothelioma.* Indeed, the relationship between asbestos and mesothelioma is so strong that many consider mesothelioma a "signal" or "sentinel" tumor.* In rare cases, mesothelioma has also been associated with irra...
1
Asbestosis
Silicosis
Anthracosis
Coal workers pneumoconiosis
Medicine
Pneumoconiosis
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single
The following rosette cataract is seen with
null
2
Steroid induced cataract
Traumatic cataract
Syndermatotic cataract
Rose thorn injury to lens
Ophthalmology
null
1eefadf6-c0eb-44cd-8281-d04adeb68264
single
Which of the following is true about typhoid?
Convalescent carriers excrete the bacilli for 6-8 weeks.Persons who excrete the bacilli for more than a year after a clinical attack are called chronic carriers.In chronic carriers, the organism persists in the gallbladder. Vi antibodies are present in about 80% 0f chronic carriersFecal carriers are more frequent than ...
2
Fecal carriers are less common
Vi antibodies are present in about 80% of chronic carriers
Gall bladder usually not involved in carrier state
Tetracycline is the DOC for carriers
Social & Preventive Medicine
Communicable diseases
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multi
A 5 yr. old male child has multiple hyperpigmented macules over the trunk. On rubbing the lesion with rounded end of pen, he developed urticarial wheal, confined to border of lesion, most likely diagnosis is:
Ans. C. Urticaria pigmentosa* It is urticaria pigmentosa.* It is cutaneous mastocytosis presenting with pigmented lesions.* On rubbing the lesions mast cells degranulate releasing histamine.* This produces the wheal and flare of the lesion. It is known as Darier's sign.Epidermal acantholysis in mid epidermis with "dila...
3
Fixed drug eruption
Lichen planus
Urticaria pigmentosa
Urticarial vasculitis
Skin
Miscellaneous
9f8dcde7-4ab4-4390-8ecc-387c17e340ce
single
Long term control of diabetes is assessed by
Ans. D i.e. HbA1c
4
Random blood sugar
Microalbuminuria/ creatinine ratio
HbA2
HbA1c
Medicine
null
5e58e064-06c9-44f7-8a4b-f79b38a6adf0
single
Primary open-angle glaucoma is associated with all of the following except:
Ans. Pars planitis
4
Diabetes mellitus
Myopia
Hypehyroidism
Pars planitis
Ophthalmology
null
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multi
Direction of water jet while doing syringing of ear should be:
In syringing (done to remove impacted wax) pinna is pulled upwards and backwards and a stream of water from the ear syringe is directed along the posterosuperior wall of the meatus.
2
Anteroinferior
Posterosuperior
Anterosuperior
Posteroinferior
ENT
null
b0dbf3bb-0859-4668-82ef-9d12ec3333b6
single
Biological value is maximum of:
Egg
1
Egg
Milk
Soyabean
Pulses
Social & Preventive Medicine
null
de7b164f-b828-442f-bc44-3bf035863901
single
Among the given hormones which are stored the longest in a cell
Hormone Supply Stored in CellSteroids and 1,25(OH)2-D3NoneCatecholamines and PTHHoursInsulin DaysT3 and T4WeeksRef: Harper; 30th edition; Pg:515
2
Insulin
T3
PTH
Testosterone
Biochemistry
Structure and function of protein
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single
The most common effect of colchicine which is dose limiting is :
null
1
Diarrhea
Dyspepsia
Retinal damage
Loss of taste sensation
Pharmacology
null
96d171c3-ed59-4539-9f65-2991a015773a
single
Not a feature of Treacher-Collins syndrome:
Ans. D. Mongoloid slant of palpable fissureMandibulofacial dysostosis is also known as Franceschetti-Klein syndrome or Treacher-Collins syndrome.Important features are as under:MicrognathiaColobomas of lower eyelidSunken cheek bonesBlind fistulas between the angles of mouth and earsDeformed pinnasAtypical hair growth e...
4
Deafness
Colobomas of lower eyelid
Hypoplasia of zygomatic bone
Mongoloid slant of palpable fissure
Pediatrics
Genetics And Genetic Disorders
f1d1ed18-131e-4d84-ae73-40c6007f2b84
single
Most potent stimulator of NaiveT-cells -
Question repeated
1
Mature dentritic cells
Follicular dentritic cells
Macrophages
B-cell
Pathology
General pathology
9dacd22c-982f-4023-a8df-4a2b7a46a0b8
single
Layers of the scalp include all of the following except-
Ans. is 'b' i.e., Adventitious layer Layers of scalp have been explained in NEET Dec.-16
2
Galea aponeurotica
Adventitious layer
Skin
Pericranium
Anatomy
Head & Neck
45ca83ff-dc48-49a8-9d42-7ac346189b18
multi
Which of the following adverse effects characteristically associated with methysergide ?
null
2
Pulmonary hypertension
Retroperitoneal fibrosis
Hepatotoxicity
Ischemic heart disease
Pharmacology
null
e8b96f11-a402-4f70-9684-d0ba21a935a4
multi
Binge eating disorder is characterized by ?
Ans. C. ObesityBinge eating disorder (BED) is characterized by insatiable cravings that can occur any time day or night, usually secretive, and filled with shame.There are no comPensatory mechanisms associated with the binge to get rid of calories, so individulas with BED are more likely to be overweight or obese, whil...
3
Normal weight
Weight loss
Obesity
Self induced vomiting
Psychiatry
null
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single
Anemia of chronic disease is characterised by
(Ref: Robbins 8/e p662) Anemia of chronic disease- Impaired red cell production associated with any chronic diseases that would be infectious/inflammatory/neoplastic. Chronic diseases produce a cytokine “IL-6” that increases the production of hepcidin from liver.  Hepcidin inhibits ferroportin function in macrophages ...
3
Increased sideroblast
Increased TIBC
Increased bone marrow iron
Increased protoporphyrin
Unknown
null
b8930b48-32e6-4700-9951-bd12426ad066
single
Choose the true statement about mit DNA:
Ans. D. It codes for less than 20% of the proteins involved in respiratory chainIn ETC there are around 67 subunits, out it 13 proteins are coded by Mit DNA, which comes around 19%.Mitochondrial DNA has high mutation rate almost 5 to 10 times that of nuclear DNA.It has 16,569 bpMitochondrial DNA has maternal inheritanc...
4
Few mutation compared to nuclear DNA
It has 3x109 base pairs
It receives 23 chromosomes from each parent
It codes for less than 20% of the proteins involved in respiratory chain
Biochemistry
Molecular Genetics
629939d5-2989-485c-8051-7ec91f016bf0
multi
Cataract in newborn is:
Ans. Zonular
1
Zonular
Coronary
Snowflake
Coical
Ophthalmology
null
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single
Drug of choice for treatment of type 2 Brittle Asthma is -
Ans. is 'd' i.e., Subcutaneous epinephrine o Brittle asthma is a type of asthma distinguishable from other forms by recurrent, severe attacks.o There are two subtypes divided by symptoms: Type 1 and Type 2, depending on the stability of the patient's maximum speed of expiration, or peak expiratory flow rate (PEFR).o Br...
4
b-adrenergic agonist
Inhaled corticosteroids
Antileukotrines DM
Subcutaneous epinephrine
Medicine
Asthma
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single
A 22-year-old woman is admitted to the hospital because of right-hand anaesthesia, that developed after an argument with her brother. She is in good spirits and seems unconcerned about her problem. There is no history of physical trauma. The neurologic examination is negative EXCEPT for reduced sensitivity to pain in a...
(D) Conversion disorder # Conversion disorder is characterized by symptoms or deficits of die voluntary motor or sensory functions dial cannot be explained by neurological or other medical conditions.> These symptoms are precipitated by psychological conflicts.> Term 'Hysteria' was used in die nineteenth century (and d...
4
Body dysmorphic disorder
Histrionic personality disorder
Parietal brain tumor
Conversion disorder
Pharmacology
Miscellaneous (Pharmacology)
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multi
A person following a road-traffic accident presented in emergency with laceration of inguinal region. On examination there was swelling of inguinal region and distal pulsation was felt; internal iliac artery was normal, common iliac and external femoral artery was normal but common femoral vein is transected. Treatment...
null
1
Vein repair with continuity
Sclerotherapy
Ligation of femoral artery and vein
Amputation below knee
Surgery
null
ab7779d0-18c3-4d45-a732-33612120f24c
single
A patient with ASD has the murmur similar to mitral regurgitation and left axis detion of 40 degrees. He is likely having:
Presence of pansystolic murmur of mitral regurgitation in a patient with ASD suggests the presence of ostium primum defect with cleft mitral leaflet or a floppy mitral valve with mitral valve prolapse. ECG shows right axis detion in ASD, and extreme left axis detion in ostium primum ASD. Clinical presentation of ostium...
4
TGA
Ostium secondum
Ostium primum
Floppy mitral valve
Pediatrics
null
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single
GLUT 4 is present in -
Ans. is 'c' i.e., Cardiac muscle* GLUT4 transporters mediate insulin dependent glucose uptake in skeletal muscle, cardiac muscle and adipose tissue
3
Endothelium
Liver
Cardiac muscle
Lens
Biochemistry
Carbohydrates
545927bc-c9c0-48c5-98a4-855a6e901674
single
Which is the best test to detect pulmonary embolism
CTPA is the first-line diagnostic test. It has the advantage of visualising the distribution and extent of the emboli or highlighting an alternative diagnosis, such as consolidation, pneumothorax or aoic dissection. The sensitivity of CT scanning may be increased by simultaneous visualisation of the femoraland poplitea...
4
D dimer assay
MRI
Ventilation Perfusion scan
CT with IV contrast
Medicine
Respiratory system
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single
A 54-year-old clerk complains of having had dysphagia for 15 years. The clinical diagnosis of achalasia is confirmed by a barium study. What is TRUE in this condition?
Dysphagia in esophageal achalasia is described as paradoxical in that it is more pronounced for liquids than solids. There are numerous reports of an increased incidence of carcinoma in achalasia, ranging from 3% to 10%. In 1975, Belsey reported a 10%. incidence in 81 patients in whom symptoms tended to occur at a youn...
1
The most common symptom is dysphagia.
In the early stages, dysphagia is more pronounced for solids than liquids
The incidence of sarcoma is increased.
Recurrent pulmonary infections are rare.
Surgery
Stomach & Duodenum
106bb8c1-7fb2-40fb-8ac2-327f733b2492
multi
Uveitis is caused by all except:
Ans. Klebsiella
4
T.B.
Staphylococcus
Streptococcus
Klebsiella
Ophthalmology
null
dfd75847-f4df-40bb-ab84-fcb5038fefe3
multi
Which of the following is false regarding plasmid
Plasmids contain their own signals for replication and can replicate independently.
4
Circular genetic material
Double stranded DNA
Extra chromosomal
Synchronised with chromosomal multiplication
Biochemistry
null
5cc9e218-a6f9-4ce9-acf2-f69baddbac40
multi
Commonest cause of right ventricular failure is ?
Ans. is 'd' i.e., Left ventricular failureRight sided hea failureo Most common cause of right sided hea failure is left sided hea failure, i.e. right hea failure occurs as a consequence of left hea failure because left hea failure increases pressure in pulmonary circulation that produces an increased burden on the righ...
4
Corpulmonale
Pulmonary involvement
Endomyocardial fibrosis
Left ventricular failure
Pathology
null
eadf0100-f37f-4bd3-af71-f15226951a7c
single
Which of the following anti-histaminie has very less cholinergic side effects?
Loratidine is a second generation anti-histamine which has lesser sedation and cholinergic side effects.
4
Promethazine
Chlorpheniramine
Hydroxyzine
Loratidine
Pharmacology
null
a8638e28-2393-4823-9101-da47173a14e9
single
following are decomposition changes except
Decomposition changes Discoloration: greenish discoloration of right iliac fossa due to sulphmethemoglobin, marbling, discoloration under surface of liver, staining of aoa, blackish discoloration of skin is due to formation of ferric sulphide. Distension: abdomen, breasts, penis, scrotum, face bloated, eyes budget out ...
4
Discoloration
Discharge
Degloving
Dilatation
Forensic Medicine
Death and postmortem changes
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multi
A 31 year old female patient complaints of bilateral impairment of hearing for the past 5 years. On examination, tympanic membrane is normal and audiogram shows a bilateral conductive deafness. Impedance audiometry shows normal curve and acoustic reflexes are absent. All of the following constitute pa of its treatment,...
The patient is showing features of otosclerosis. It is a condition due to new spongy bone formation. About 50% of the cases may have a positive family history and deafness stas between the age of 20-30 years. Non surgical treatment of otosclerosis includes use of hearing aid and sodium fluoride. Use of high doses of so...
1
Gentamicin
Hearing aid
Stapedectomy
Sodium fluoride
ENT
null
a8338743-57d1-455a-b44b-69e9eb067a90
multi
A 43-yrs-old female patients, who has sustained a head injury in a fall, has significant problems wit memory. Her brain injury is most likely to the
The area of the brain most closely associated with memory is the temporal lobe, paicularly the hippocampus. PE presents with a syncopal episode up to 15 percent of the time. Altered mental status and generalized seizures may also be the presenting complaint, especially in the elderly. The most common presenting symptom...
1
Temporal lobe
Frontal lobe
Parietal lobe
Occipital lobe
Surgery
null
698b9d08-8ac1-42eb-bf13-8515cca5f63d
multi
Antidote for ethylene glycol poisoning is/are: a) Methyl violet b) Fluconazole c) Fomepizole d) Ethyl alcohol
null
2
ac
cd
ad
bc
Pharmacology
null
1ee618bb-4cf0-470a-8895-0eaec35f9975
single
Which among the following is not a beta lactamase resistant Penicillin?
Ans. is 'b' i.e., Carbenicillin
2
Methicillin
Carbenicillin
Nafcillin
Oxacillin
Pharmacology
null
1f1c517b-5f2f-4232-a332-c14dabd8a883
single
Class IV Kennedy Classification is:
The following is the Kennedy classification: Class I: Bilateral edentulous areas located posterior to the natural teeth. Class II: A unilateral edentulous area located posterior to the remaining natural teeth. Class III: A unilateral edentulous are with natural teeth remaining both anterior and posterior to it. Class I...
4
Bilateral edentulous area located posterior to the remaining natural teeth.
Unilateral edentulous area located posterior to the remaining natural teeth.
Unilateral edentulous area with natural teeth remaining both anterior to the remaining natural teeth and posterior to it.
A single but bilateral (crossing the midline) edentulous area located anterior to the remaining natural teeth.
Dental
null
f6c76e86-a0e5-4407-93eb-010141dcddc8
multi
Earliest fetal anomaly to be detected by USG :
Anencephaly
2
Hydrocephalous
Anencephaly
Achondroplasia
Spina bifida
Gynaecology & Obstetrics
null
c87cd9ce-def0-49f6-a75d-60c0517a8d87
single
A 54-year-old male nonsmoker is seen with complaints of a flulike illness. Initial symptomatic treatment is provided. Two days later, he returns, as he is still not feeling well. His primary physician prescribes a macrolide along with the symptomatic treatment. After 5 days of this treatment, the patient says he is run...
This x-ray shows a nonhomogeneous airspace density in the left middle and lower zones with areas of incomplete consolidation and evolving pneumatocele formation. The left diaphragm is raised and the trachea appears shifted to the left, suggesting loss of volume of the left lung. There is minimal blunting of the left co...
4
Septic ahritis
Endocarditis
Brain abscess
Reye syndrome
Radiology
Respiratory system
c1a49e19-4984-4a6a-8acb-c927b5a920b6
multi
Subclan steal syndrome is due to
Subclan steal syndrome refers to steno-occlusive disease of the proximal subclan aery with retrograde flow in the ipsilateral veebral aery and associated cerebral ischaemic symptoms.CausesClinical presentationIpsilateral upper limbNeurological, radiationCongenital Weak or absent pulseDecreased blood pressure (>20 mmHg)...
2
Blockage of first pa of subclan aery
Blockage of second pa of subclan aery
Blockage of third pa of subclan aery
Thrombosis of subclan vein
Pathology
All India exam
e94ea92f-3d1b-4f02-949c-e37f05e38d4f
single
GABA is produced from:
Glutamate
3
Alanine
Glycine
Glutamate
Glutamine
Physiology
null
81f3ce8d-ce5d-4da1-a6b3-b8228d4856ce
single
Palpatory thud, an audible snap is seen in
A foreign body in trachea may move up and down the trachea between the carnia and the undersurface of vocal cords causing "audible slap" and "palpatory thud&;.Symptoms and signs of foreign bodies at different levelsSite of foreign bodiesSymptoms and signsLarynxChoking, Cyanosis, Complete obstruction leading to death* P...
1
Tracheal foreign body
Bronchial foreign body
Laryngeal foreign body
Foreign body in ear
ENT
Larynx
4123ffcc-6830-456b-8b4e-669fac15fae4
single
A drug used in LUMINATE programme for non-infectious uveitis is –
Voclosporin is an immunomodulatory drug which inhibits the enzyme calcineurin. The chemical structure of voclosporin is similar to cyclosporine with a difference in one amino acid, leading to superior calcineurin inhibition and less variability in plasma concentration. The LUMINATE (Lux Uveitis Multicenter Investigatio...
2
Cyclosporine
Voclosporin
Methotrexate
Infliximab
Ophthalmology
null
d1a4d2e7-43f2-4634-b991-f4938c88cebb
single
Average of length of maxillary cuspid is:
null
1
26 mm
33 mm
21 mm
18 mm
Dental
null
57815d37-3ae7-417d-ad46-4eccf10f80d5
single
The nerve root blocked in pudendal block is
Pudendal nerve block : Pudendal nerve arises from S2,3,4. Doesn't relieve the pain of labor Cause perineal analgesia and relaxation Ref: Dutta Obs 9e pg 480.
3
L 1,2,3
L 2,3
S 2,3,4
S 4
Gynaecology & Obstetrics
General obstetrics
00b3f0c1-994f-4eb2-9caa-e37dd57c19c9
single
A 45 year old male , known case of diabetes mellitus from last 15 years ,presents with Diabetic ketoacidosis . What shall be the initial line of management?
Diabetic ketoacidosis (DKA) is a problem that affects people with diabetes . It occurs when the body stas breaking down fat at a rate that is much too fast. The liver processes the fat into a fuel called ketones, which causes the blood to become acidic. Initial management is - 0.9% saline Treatment of choice - Insulin ...
3
3 % saline
5% dextrose
0.9 % saline
Colloids
Medicine
DNB 2018
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multi
All of the following are true regarding pilonidal sinus except: September 2009
Ans. A: Seen predominantly in women Pilonidal disease is described back as far as 1833, when Mayo described a hair-containing cyst located just below the coccyx. Hodge coined the term "pilonidal" from its Latin origins in 1880. Pilonidal disease describes a spectrum of clinical presentations, ranging from asymptomatic ...
1
Seen predominantly in women
Occurs only in sacrococcygeal region
tendency for recurrence
Obesity is a risk factor
Surgery
null
c3738a59-7894-4e55-9854-efe08aedc855
multi
Fever & hemorrhagic rash are seen in ail except:
Ans: D (Sand,.) [Ref: Ananthanarayan 8th/514.518-19; Harrison 18th/l50,1629; Medical microbiology by Greenwood 16 th /4961The viral HF syndrome is a constellation of findings based on vascular instability and decreased vascular integrity. An assault, direct or indirect, on the microvasculature leads to increased permea...
4
Dengu fever
Lassa fever
Rift Valley fever
Sand fly fever
Microbiology
Virology
c17b05e7-6815-4b07-9917-72b3ab94ab9b
multi
Argentaffin cells in the GIT produce
Their granules contain a chemical called serotonin, which stimulates smooth muscle contractions.
4
Gastrin
Pepsin
HCl
None of the above
Anatomy
Systemic histology
84aa7cd3-d2f6-49d4-a2cd-a1ab53324c85
multi
A 46-year-old man has a swelling in the scrotum. It shows clear transillumination anterior to the testis when a light is applied to the scrotum in a dark room. This physical exam is most consistent with?
In adults, this is diagnostic, but in children, transillumination is also seen in an indirect inguinal hernia. As epididymal cyst may transilluminate but is posterior to the testis.
3
Cyst of the epididymis
Torsion of testis
Hydrocele
Direct inguinal hernia
Surgery
Urethra & Penis
3c372938-0d3a-43c0-a2ae-4e6d55a8f27f
single
A 35-year patient recalls episodes where he smells a pungent odor, becomes sweaty and loses consciousness. His family member says while unconscious he was having facial twitching with lip-smacking movements. What is the most probable diagnosis?
The patient is exhibiting focal seizures which are accompanied by transient impairment of patient's ability to maintain normal contact with environment. Chewing, lip smacking, swallowing or picking movements of hands are called Automatism. Full recovery after the episode range from seconds to an hour. Due to involvemen...
1
Focal seizures
Hysteria
Atonic seizures
Myoclonic seizures
Medicine
Epilepsy and EEG
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multi