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All of the following statements about leprosy are true except -
A defaulter is a leprosy patient on MDT , who has not collected treatment for 12 consecutive months Reference; Park&;s Textbook of preventive and social medicine, 24th edition.Pg no. 340
3
Multibacillary leprosy is diagnosed when there are more than 5 skin patches
New case detection rate is an indicator for incidence of leprosy
A defaulter is defined as a patient who has not taken treatment for 6 months or more
The target for elimination of leprosy is to reduce the prevalence to less than 1 per 10,000 population
Social & Preventive Medicine
Communicable diseases
4091b1ea-d293-4873-a5a0-7a55915d09bc
multi
The characteristic features of El tor cholera are all except
Ans. is 'c' i.e., Secondary attack rate is high in family El Tor vibrio . It is much hardier than classical vibrios, capable of surviving in the environment much longer. . The severity of illness is much less, with a large propoion of mild and asymptomatic infections. . Moality is low and the carrier rate is high. . Fe...
3
More of subclinical cases
Moality is less
Secondary attack rate is high in family
El tor vibrio is harder and able to survive longer
Microbiology
null
d510aacd-e2a5-4132-a05f-52e9ec959644
multi
A normal-anion-gap metabolic acidosis occurs in patients with-
Alkali can be lost from the gastrointestinal tract from diarrhea or from the kidneys (renal tubular acidosis, A). In these disorders, reciprocal changes in and result in a normal anion gap (AG). * In pure non-AG acidosis, therefore, the increase in above the normal value approximates the decrease in .
1
Diarrhoea
Diabetic ketoacidosis
Methyl alcohol poisoning
Acute renal failure
Medicine
Fluid and electrolytes
764eb539-62b8-4057-b05f-98ebd0f79332
single
Thermatomyces is used in?
Ans. a (Sterilization standardization). (Ref. Ananthnarayan, Microbiology, 4th ed., 26, 29)# For determining the efficiency of moist-heat sterilization = Spores of bacillus stearothermophilus.# For determining the efficiency of dry-heat sterilization = Spores of non-toxigenic strains of C.tetani.
1
Sterilization standardization
Gram staining
Selective media preparation
Antibiotic sensitivity
Microbiology
General
ddb1742f-db3f-4c14-83dd-c25fdb6d6287
single
Large for date baby may be due to:
Beckwith syndrome is charectorised by : macrosomia, macroglossia and omphalocele. cytogenic location is 11q15 and is associated with wilm's tumour of kidney. other risk factors which our likelihood of large fetus are : large size of parents multiparity prolonged gestation increased maternal age male fetus previous infa...
4
Beckwith syndrome
Diabetic mother
Genetic predisposition
All of the above
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
f859527b-ed71-49e5-bbaf-08d86730b7c3
multi
The ratio of fat cells and blood cells in bone marrow is-
Fat to Cell ratio - in bone marrow should be 1:1 so 1/2 hemopoietic cells and 1/2 are fat cells myeloid: erythroid ratio -in bone marrow -should be 3:1 -an increased ratio is found in infections, chronic myelogenous leukemia, or erythroid hypoplasia.
3
1:04
1:02
1:01
2:01
Pathology
miscellaneous
9572ab4b-2cc4-474c-a7ad-b975e5817fdf
single
Incidence of Turner syndrome: MAHE 10
Ans. 1: 2500
4
0.388888889
0.736111111
1.083333333
1.777777778
Forensic Medicine
null
35930152-3c23-409d-a298-3214476db1e3
single
In secondary syphilis, true about rash is –
Initial lesion of secondary syphilis is characterized by macules which are :  i) Non-pruritic (asymptomatic)         ii) Bilateral symmetrical
3
Pruritic
Vesicular
Asymptomatic
Tender
Dental
null
f3e87300-d1e8-454c-a02d-d5764e307cbd
multi
Bedsore is an example of:
Ans. (b) Trophic ulcer* Bedsore is a pressure ulcer. Most common in sacrum site due to persistent pressure in the back.* This is a type of trophic ulcer.* This can be prevented by frequent change of positioning of the bedridden patient and using Water/Aqua bed.* Once bedsore is formed it is difficult to treat.* Treatme...
2
Tropical ulcer
Trophic ulcer
Venous ulcer
Post thrombotic ulcer
Surgery
Plastic & Reconstructive Surgery
86340e66-471e-4d96-81c8-2d24b5f00512
single
All are examples of hereditary neuropathies associated with abnormal lipid metabolism, EXCEPT:
Rare Hereditary Neuropathies A) Hereditary Disorders of Lipid Metabolism 1. Metachromatic leukodystrophy 2. Krabbe disease (globoid cell leukodystrophy) 3. Fabry disease 4. Adrenoleukodystrophy/adrenomyeloneuropathy 5. Refsum disease 6. Tangier disease 7. Cerebrotendinous xanthomatosis B) Hereditary Ataxias With Neurop...
3
Metachromatic leukodystrophy
Refsum disease
Cockayne syndrome
Fabry disease
Medicine
null
eb0987c6-e1c0-4e49-90fc-b4b492acc485
multi
Retinopathy of prematurity is commonly predisposed by –
null
1
Less gestation age
Low birth weight
O2 toxicity
Carbohydrate excess
Pediatrics
null
b14042a8-de64-408a-aaac-540ba8b5cfeb
single
The drug recently approved to be used along with phenteramine in the management of obesity is
null
3
Lorcaserin
Orlistat
Topiramate
Sibutramine
Pharmacology
null
4ee5763a-5eba-4e25-936c-4321cd66b7ff
single
Most common sets of Metastases of carcinoma bronchi
Distant metastases blood stream are widespread and early.The sites affected,in descending order of involvement,are:the liver,adrenals,bones,pancreas,brain,opposite lung,kidneys & thyroid. Textbook of pathology-6th edition,Harsh Mohan,6th edition,page no:502
1
Liver + Bones
Prostate
Kidney
Breast
Surgery
Cardio thoracic surgery
41fc199d-a232-40e0-95e3-815ba10117a4
single
Impoance of CVP measurements is :
A i.e. Need for blood transfusion
1
Need for blood transfusion
Assess amount of fluid to be given
Need for inotropic suppo
All
Anaesthesia
null
02c2d0ae-8648-44b8-9e27-a83714dfcfce
multi
Products accumulated in Hunter 's syndrome are
B i.e Dermatan sulfate
2
Keratan sulfate
Dermatan sulfate
Chondroitin sulfate
All
Biochemistry
null
8617765d-dcb4-44a6-a868-4d84b59bf8d8
multi
Characterstic CVS leison in syphils is -
Ans. is 'b' i.e., Aoic ring dilatation Syphilitic aoitis usually affects the proximal ascending aoa, paicularly the aoic root, resulting in aoic dilatation and aneurism formation.
2
Aneurysm of arch of aoa
Aoic ring dilatation
Medial necrosis
All
Pathology
null
ec3eca14-25ae-4c45-be6c-4f495a35bdb5
multi
Which of the following is not a radiographic indication of systemic disease?
Because systemic disorders affect the entire body, the changes manifested in the appearance of the jaws in diagnostic images are usually generalized and often nonspecific, making it difficult to identify the diseases based on imaging characteristics alone. The general changes that can be seen in the jaws include the fo...
1
Change in mature tooth density
Change in cortical bone density
Change in the number of trabeculae
Change in overall bone shape and size
Radiology
null
87d2f2b3-dc7b-4178-8bc6-bcafe6c055b5
multi
Drug used for obesity:
(A) Orlistat # Anti Obesity Drugs:> Sibutramine: serotonin and nor-epinephrine reuptake inhibitor.> Orlistat: gastric and pancreatic lipase inhibitor.> Rimonabant: Selective cannabinoid receptors antagonist. Other Drugs> Leptin analogs: Under investigational study.> Orlistat is a synthetic hydrogenated derivative of a ...
1
Orlistat
Rivatat
Nitousoxide
Phenylepherine
Medicine
Miscellaneous
bf39b6d2-0a60-41f6-b1e8-82bc3edb870a
single
Which of the following will quality as a class III exposure to rabies?
<p> caterogies of contact and post exposure prophylaxis in rabies:- Category 1: touching or feeding animals, licks on intact skin. PEP- none. Category 2: nibbling of uncovered skin, minor scratch/abrasions without bleeding. PEP- immediate vaccination and local treatment of wounds. Category 3: single/ multiple transderm...
3
Licks on intact skin a dog
Bites by wild animals
Bites on legs by a dog
Drinking unboiled milk of a suspect animal
Social & Preventive Medicine
Communicable diseases
8d666c0a-90bb-4560-b7ed-e2ccca67b62b
single
Type I hypersensitivity is mediated by which of the following immunoglobulins?
Type I hypersensitivity reaction is IgE dependent. Cytotoxic IgE antibodies are fixed on the surface of tissue cells ( mast cells and basophils) in sensitized individuals. The antigen combines with the cell fixed antibody, leading to release of pharmacologically active substance that produces the clinical reaction. Ref...
4
Ig A
Ig G
Ig M
Ig E
Microbiology
Immunology
140e1ef2-28d0-48d3-8c43-148fdab7344b
single
Which of the following should be the line of management in a pregnant female with controlled diabetes?
Ans. b (Pregnant females with controlled diabetes are more likely to deliver child by normal vaginal delivery without any complication). (Ref. Dutta, Obstertics, 6th ed., p 284)DIABETES IN PREGNANCY# Gestational diabetes usually begins in the second half of pregnancy, and goes away after the baby is bom.Effects on the ...
2
Even controlled diabetes in pregnancy does not disappear on its own and needs extensive treatment even after delivery
Pregnant females with controlled diabetes are more likely to deliver child by normal vaginal delivery without any complication.
In all females with gestational diabetes, blood sugar levels remain too high, and daily insulin therapy is essential.
LSCS is must in almost every case of gestational diabetes
Gynaecology & Obstetrics
Miscellaneous (Gynae)
e8662762-7b8f-4ba7-a429-9f6c6dd4b072
multi
SIADH feature
(A) Hyponatremia with sodium excretion > 20mEq/l # Syndrome of Inappropriate Antidiuretic Hormone (ADH) secretion (SIADH) is defined by the hyponatremia and hypo-osmolality resulting from inappropriate, continued secretion or action of the hormone despite normal or increased plasma volume, which results in impaired wat...
1
Hyponatremia with sodium excretion > 20 mEq/L
Hypernatremia with hypokalemia
Hypernatremia with Na+ excretion < 20 mEq/L
Hyponatremia with hyperkalemia
Medicine
Miscellaneous
a3ba4b69-8ca0-44d0-82bb-2ba12a338a7b
single
All of the following are true regarding enoxaparin EXCEPT:
Ref KDT, 6th ed. pg. 599-600* Low molecular weight heparin, Enoxaparin, inhibits only factor Xa whereas unfractionated heparin inhibits both factor IIa and factor Xa.
2
It has higher and predictable bioavailability
It act by inhibiting both factor Ila and factor Xa
Monitoring is not required
It has more favorable pharmacokinetics
Pharmacology
Hematology
02b6e8e2-392d-4aa6-922b-fab3a9de01ef
multi
Which is true about Widal reaction -
Ans. is 'a' i.e., Antibody to 'H' antigen appears first and persists
1
Antibody to H Ag appears first and persists
Antibody to 0 Ag appears first and persists
Antibodies to H & 0 Ag appears simultaneously and persists
None of the above
Microbiology
null
01c8b111-a1fb-4a3b-8edb-b5733c6aea62
multi
Blow out carotid is characteristically seen in
History of radiation exposure followed by radical neck dissection increases the risk of carotid blowout in head and neck cancers. * Carotid blowout refers to rupture of the carotid and its branches* It is one of the most devastating complications associated with therapy for head and neck cancers * Carotid blowout tends...
4
Sistrunk operation
Thyroidectomy
Parathyroidectomy
Radical neck dissection
Anatomy
Head and neck
715defae-2749-40df-a357-ac4a091e2206
multi
Multiple 'punched out holes' in skull are seen in:
Ans. Multiple myeloma
2
Hyperparathyroidism
Multiple myeloma
Thalassemia major
Acromegaly
Radiology
null
281f5ee2-8a0c-445b-98ef-8a7ea9c8425c
single
Placental alkaline phosphatase is marker of
Placental alkaline phosphatase is a marker of seminoma. Also know Gamma-glutamyl-transpeptidase is marker of - seminoma testis AFP is not produced by - seminomas and Choriocarcinomas
4
Theca cell tumour
Teratoma
Choriocarcinoma
Seminoma
Anatomy
Urology
1cc80d08-ee1c-4af3-a59f-02a140f9deab
single
Which one of the following laboratory tests differentiates leukemoid reaction from chronic myeloid leukemia ?
null
1
LAP (leukocyte alkaline phosphatase)
LCA (leukocyte common antigen)
MPO (myelo-peroxidase)
TRAP (tartrate resistant alkaline phosphatase)
Medicine
null
aab785b4-44f3-4b7f-9c90-c8e955731540
single
Randomisation is useful to eliminate:(1994)
Ans: bRef: Park, 17th ed, p. 72 & 18th ed, p. 76
2
Observer bias
Confounding factors
Patient bias
Sampling bias
Social & Preventive Medicine
Epidemiology
65848bd9-4c61-4b86-b1ce-4cfaea76c1e4
single
Which of the following is not associated with actions of siuins?
Siuins They are a family of NAD-dependent protein deacetylases. There are at least 7 types They have non-redundant functions designed to adapt bodily functions to various environmental stresses, including Food deprivation and DNA damage. Functions:- These include proteins that inhibit metabolic activity Reduce apoptosi...
4
Inhibit metabolic activity
Reduce apoptosis
Increased insulin sensitivity
Reduced by calorie restriction
Pathology
Miscellaneous
0e6a007b-3609-4343-9732-a407c7d89cf2
single
Which of the following is the most common origin of cerebral metastasis?
Lung: 40% Breast : 10 - 30% Melanoma : 5 - 15% Unknown : 15%
1
Lung cancer
Breast cancer
Melanoma
Colon cancer
Surgery
null
f583e168-b3e4-48ba-9f66-f8f278ee490a
single
A 50 year old male patient complains of reduced mouth opening. Patient gives h/o RTA 1 week back. A panoramic X-ray was taken using fast intensifying screen. Which of the following is not true about the screen used in this patient?
Fast screens have large phosphor crystals and efficiently convert X-ray photons to visible light, but produce images with lower resolution. Fast screens also have a thicker phosphor layer and a reflective layer, but these properties also decrease sharpness. In deciding on the combination to use, the practitioner must c...
4
They have large phosphor crystals
They produce images with lower resolution
They have a thicker phosphor layer and a reflective layer
They increase image sharpness
Radiology
null
5b842410-0bfd-4ae0-bcd4-0bfc90483a39
multi
Chronic asbestos exposure causes
null
1
Mesothelioma
Carcinoma of pharynx
Leukoplakia
Erythroplakia
Medicine
null
be464d96-697a-4a3e-9179-c308bba5f05f
single
The most impoant factor decreasing the systemic bioavailability of orally administered drugs is
Bioavailability is defined as the fraction of unchanged drug reaching the systemic circulation following administration by any route. For an intravenous dose of the drug, bioavailability is assumed to be equal to unity. For a drug administered orally, bioavailability may be less than 100% for two main reasons: 1. The i...
2
Incomplete dissolution of oral dosage form
First pass metabolism
Drug degradation by gastric acid
Drug degradation by digestive enzymes
Pharmacology
General anatomy
1e9f8ed0-3a3f-49b2-afc2-4688c60cdc0e
multi
Which cells produce surfactant in conducting part of the lung?
Ans. (d) Clara cells(Ref: Robbins 9th/pg 670; 8th/pg 679)Club cells, also known as bronchiolar exocrine cells, originally known as Clara cells, are dome-shaped cells with short microvilli, found in the small airways (bronchioles) of the lungs, produce substances similar to surfactant.
4
Goblet cells
Brush cells
Basal cells
Clara cells
Pathology
Respiration
398be206-b6f1-4866-b075-25e53245910c
single
Normal cardiac index is
Experiments have shown that the cardiac output increases approximately in propoion to the surface area of the body. Therefore, cardiac output is frequently stated in terms of the cardiac index, which is the cardiac output per square meter of body surface area. The average human being who weighs 70 kilograms has a body ...
1
3.2
2.8
2.4
4.4
Physiology
Cardiovascular system
dcab83bd-2163-4aef-a8bd-09215454872c
single
Sequence of events, after salpingitis, in gonorrhoeal pelvic infection is: March 2013
Ans. B i.e. Pyosalpinx, hydrosalpinx, pelvic abscess
2
Hydrosalpinx, pyosalpinx, pelvic abscess
Pyosalpinx, hydrosalpinx, pelvic abscess
Pelvic abscess, hydrosalpinx, pyosalpinx
Pelvic abscess, pyosalpinx, hydrosalpinx
Gynaecology & Obstetrics
null
1f016c82-36d1-47e9-b392-c1b0be631b71
single
Antrochoanal polyp is characterized by:
Nasal polyps are non-neoplastic masses of edematous nasal or sinus mucosa. They do not bleed on touch and are insensitive to probing and never present with epistaxis or bleeding from nose. Recurrence is uncommon in case of antrochoanal polyp. Antrochoanal polyps arise from maxillary arum and then grow into choana and n...
3
Usually bilateral
It is of allergic origin
It arises from maxillary antrum
All
ENT
null
45c2a979-90a9-4c5a-93c3-9853603be4a8
multi
Most common chromosomal defect is:
Ans: a (Downs) Ref: Robbins, 7th ed, p. 175Down's syndrome is the most common of the chromosome disorders and a major cause of mental retardation.Cytogenetic abnormalityNon disjunction (MC) = 95%Translocation (robertsonian) = 4 %Mosaicism = 1%Increased maternal age is the main risk factor .Translocation carriers carry ...
1
Down's
Turner
Edward
Patau
Pathology
Genetics
423d5d29-5d8e-4a2d-b6ca-8dd41e27cd83
single
Level of which clotting factor falls first after giving warfarin?
Ans. is 'c' i.e., VII
3
V
VI
VII
VIII
Pharmacology
null
15826a03-cbf5-4053-8ea8-6358bd9fc87b
multi
A 32 year old patient with history of recurrent headache was sent for fundus evaluation. He was found to be having generalized aerial attenuation with multiple cotton wool spots and flame shaped haemorrhages in both eyes. The most likely cause is:
Hypeensive retinopathy
2
Diabetic retinopathy
Hypeensive retinopathy
Central retinal aery occlusion
Temporal aeritis
Ophthalmology
null
99a3076a-1980-4668-9174-5b106160200c
multi
Pacemaker of respiration
null
4
Dorsal nuclear group
Apneustic centr
Pnemotaxic centre
Pre Botzingeer complex
Physiology
null
62e9a497-1543-483f-a702-8078a01476a3
single
A person with radiologically confirmed reflux nephropathy develops nephrotic range proteinuria. Which of the following would be the most likely histological finding in the patient?
The pathogenesis of primary FSGS is unknown. Some investigators have suggested that FSGS and minimal-change disease are pa of a continuum and that minimal-change disease may transform into FSGS. Others believe them to be distinct clinicopathologic entities from the outset. In any case, injury to the podocytes is though...
1
Focal segmental glomerulosclerosis
Nodular glomerulosclerosis
Membranous glomerulopathy
Proliferative glomerulonephritis with crescents
Pathology
Urinary tract
d6aa29a5-917e-4150-b281-d23c0ba4995e
multi
Thymic hypoplasia is:
DiGeorge Syndrome (Thymic Hypoplasia) DiGeorge syndrome is caused by a congenital defect in thymic development resulting in deficient T-cell maturation. The disorder is a consequence of a developmental malformation affecting the third and fouh pharyngeal pouches, structures that give rise to the thymus, parathyroid gla...
3
Wiskott Aldrich syndrome
Henoch Schonlein disease
Digeorge syndrome
Bloom syndrome
Pathology
Miscellaneous
088f821d-5105-4b68-85de-c55f21c199e8
single
Feature of human hair are all EXCEPT:
Differences b/w Human and Animal hair- Trait Human hair Animal hair General Fine & thin Coarse & thick Cuticle Scales sho, broad, flattened/ thin. Scales large, wavy projections/step-like projections. Coex Thick, 4-10 times as broad as medulla. Thin, rarely more than twice as broad as medulla Medulla Varies, narrow, co...
2
Cuticular scales are sho and flattened
Medulla is continuous and wide.
Coex is thick and medulla is one third of shaft diameter
Pigment in medulla is light and broken.
Forensic Medicine
null
22a10468-6be5-4679-b1d8-1848db18f92b
multi
"Classical phenyl ketonuria" is caused by deficiency of
(Phenylalanine hydroxylase) (470 - RS 7th) (366 - U.S)PHENYLKETONURIA - 5 types of hyperphenylalaminemiasHYPER PHENYLALANINEMIASTypeConditionProbable enzyme defectTreatmentIClassical phenyl ketonuriaPhenylalanine hydroxylaseLow phenylalanine dietIIPeristent hyperphenyl alaninaemiaDecreased phenylalanine hydroxylase enz...
2
Phenylalanine transaminase
Phenylalanine hydroxylase
Tyrosine transaminase
Tyrosine hydroxylase
Biochemistry
Proteins and Amino Acids
61a08891-b452-454e-90d1-e6160cad0ccf
single
Oral pill may prevent the development of :
Ovarian malignancy
2
Carcinoma breast
Ovarian malignancy
Sub - mucous fibroid
All of the above
Gynaecology & Obstetrics
null
6b462be0-cd41-45e1-ad19-a5fa6c956673
multi
Aldosterone is secreted by-
Ans. is 'a' i.e., Zona glomerulosa * The adrenal gland consists of an outer cortex and inner medulla. The hormones secreted by the adrenal cortex are called corticosteroid, which are classified into glucocorticoids, mineralocorticoids and androgens. The hormones secreted by the adrenal medulla are epinephrine and some ...
1
Zona glomerulosa
Zona fasiculata
Zona reticularis
Adrenal medulla
Physiology
Endocrinology and Reproduction
d183646c-4650-4f37-9fac-b3142880a379
single
A patient of post-cholecystectomy biliary stricture has undergone an ERCP three days ago. Following this she has developed acute cholangitis. The most likely organism is
The most common bacteria linked to ascending /acute cholangitis is Escherichia coli(25-50%),followed by other gram negative bacilli like Klebsiella(15-20%),proteus and pseudomonas.Among gram positive,enterococcus is common(10-20%)and anaerobes like Clostridium. Reference:SRB's manual of surgery,5th edition,page no:643
1
Escherichia colli
Bacillus fragilis
Streptococcus viridans
Pseudomonas aerogenosa
Surgery
G.I.T
d074820d-1dfc-4c8f-b73f-804ec9a961b9
single
A 55-year-old male firefighter is admitted to the hospital after blunt trauma to his right axilla. Examination reveals winging of the scapula and partial paralysis of the right side of the diaphragm. Which of the following parts of the brachial plexus have been injured?
The winged scapula results from a lesion of the long thoracic nerve, which supplies the serratus anterior muscle. This muscle is responsible for rotating the scapula upward, which occurs during abduction of the arm above the horizontal. The long thoracic nerve comes off the C5 to C7 roots of the brachial plexus. The di...
3
Cords
Divisions
Roots
Terminal branches
Anatomy
Upper Extremity
7aa5185e-64f7-4424-a486-a3f2d47002c8
single
Calcitonin is secreted from -
Calcitonin is a hypocalcemic peptide hormone that in several mammalian species acts as an indirect antagonist to the calcemic actions of PTH. Calcitonin is produced by the thyroid medullary C cells, derived from the neural crest derivatives from the ultimobranchial body. The C cells are interspersed throughout the thyr...
3
Ancinar cells of thyroid
Chief cells of parathyroid
"C" cells of thyroid
Oxyphil cells of parathyroids
Medicine
Endocrinology
9c2070ba-2308-4336-b697-fd45254035e8
single
Luteal phase defect is best diagnosed by :
Endometrial biopsy
2
Serum progesterone levels
Endometrial biopsy
Basal body temperature
Ultrasonography
Gynaecology & Obstetrics
null
332267c5-5d09-4798-a306-5221616f091a
single
Calculus is most commonly seen in which salivary gland:
Stone formation is most common in submaxillary (submandibular) gland (80-90% cases) followed by parotid gland (10-20%). It can occur at any age with a predilection for men. Predisposing factors for stone formation are systemic disease (Hyperparathyroidism, hypercalcemia, gout, diabetes and hypeension) therefore submand...
4
Sublingual
Palatal
Parotid
Submandibular
ENT
null
19aa01af-f8ce-471f-8071-fd9d0f201500
single
Most common indication of liver transplantation in children:-
Indications of Liver Transplantation MC indication of LT HCV induced cirrhosisQ 2nd MC indication of LT Alcoholic liver diseases MC indication of pediatric LT Biliary atresiaQ MC metabolic disorder requiring LT Alpha-1 antytrypsin deficiencyQ MC indication for LT following acute liver failure Acetaminophen toxicityQ
1
Biliary atresia
Wilson's disease
Hemochromatosis
Primary biliary cirrhosis
Surgery
NEET 2019
1871516b-e496-4a38-acad-7b9e5cbe8eb7
single
Which of the following is typical of apoptosis?
Apoptosis is characterized by the activation of endonucleases, which leads to DNA fragmentation. The chromatin of apoptotic nuclei appears clumped as inpyknosism, but karyolysis does not occur. Nuclei may become fragmented, but this fragmentation is distinct from the mitotic division. Apoptosis does not induce an influ...
2
Activation of DNA synthesis, as in the mitotic cycle
Activation of endogenous endonucleases
Reduced cytosolic free calcium
Karyolysis
Pathology
General pathology
587e0987-cdac-410c-98eb-ac38d0cb682f
single
Indications for fine needle aspiration in liver abscess are
Indications of fine needle aspiration in liver abscess are - in case of large abscess (>10cm), infected abscess, failure of drug therapy, large left lobe abscess, seronegative, abscess in pregnancy where drug therapy cannot be used. Reference :SRB edition 5 ,page no.599
4
Recurrent
Left lobe
Refractory to treatment after 48-72 hrs
> 10 cms size
Surgery
G.I.T
c61e6b5c-a20d-4e9a-8530-2f94919a8919
single
Corticosteroids are potent suppressors of the body’s inflammatory response. Which of the following conditions or actions do they suppress?
Option C: Corticosteroids suppress eosinophils, lymphocytes, and natural killer cells, inhibiting the natural inflammatory process in an infected or injured part of the body. Option A: Excessive corticosteroid therapy can lead to Cushing’s syndrome. Options B and D: Corticosteroids do not suppress the pain receptors an...
3
Cushing syndrome
Pain receptors
Immune response
Neural transmission
Dental
null
b15e6670-b733-424a-9a52-951ceca9aa72
single
Group A streptococcus causes all except -
Ans. is 'd' i.e., Epidermolysis bullae
4
Scarlet fever
Erysipelas
Impetigo
Epidermolysis bullae
Microbiology
null
3edf8314-249d-4aa3-8935-72d312095fbc
multi
Investigation of choice to evaluate intracranial hemorrhage of less than 48 hours is -
Ans. is 'a' i.e., CT o Procedure of choice for emergent evaluation of acute intracerebral hemorrhage - CT scan.
1
CT scan
MRI
PET
SPECT
Radiology
Brain Imaging: Anatomy, Trauma, and Tumors
3afa0cc0-79b2-4f0e-ad1b-474f7bb231d2
single
Fredrich's ataxia is caused by which type of mutation-
Ans. is 'b' i.e., Expanded trinucleotide repeat o Freidrich ataxia is an autosomal recessive disorder.o It is caused by loss of functional mutation in frataxin gene (FxN) gene.o Frataxin gene is located on chromosome 9ql 3.o Majority of patients have an expanded trinucleotide repeat in intron 1 of both alleles of frata...
2
Point mutation
Expanded trinucleotide repeat
Missense mutation
Inversion
Medicine
Ataxic Disorders
0e544944-bc73-4d74-90bd-3b9e6634b39e
single
Wound with bloody discharge belongs to which grade as per Southampton wound grading system
Southampton wound grading system for healing and injection : Grade 0 is normal healing. Grade 1 is with bruising / mild erythema. Grade 2 is severe erythema with other features of inflammation at or around wound. Grade 3 is serous or bloody discharge. Grade 4 is presence of pus or deep infection or tissue break - down...
3
Grade 1
Grade 2
Grade 3
Grade 4
Surgery
null
f6a4d100-3fa3-499d-9353-e90291ff1821
single
Cracked nipple may be-
• This may occur during lactation and be the forerunner of acute infective mastitis. • If the nipple becomes cracked during lactation, it should be rested for 24–48 hours and the breast should be emptied with a breast pump. • Feeding should be resumed as soon as possible.
4
Due to syphilitic chancre
Cause of retention cyst
Pagets disease of nipple
Forerunner of breast abscess
Surgery
null
d0ee7a65-1cc3-430f-a153-d60282795ada
single
Which of the following is used for Rickettsia -
null
1
Weil-Felix reaction
Rose-waler test
Poul-Bunnel test
VDRL
Microbiology
null
73ec2ce2-e643-4a45-aad1-acb48ed9a7d2
single
Common design which can be employed while fabricating a sanitary pontic:
Fishbelly pontic is also known as conventional pontic. Perel pontic is also known as modified sanitary pontic or arc-fixed partial denture.
4
Bar sanitary pontic.
Fish-belly pontic.
Perel pontic.
All of the above.
Dental
null
a0d37cf7-24e0-4024-aaaa-0143083f7d10
multi
Which is not a feature of pilonidal sinus:
"Recurrence is common, even though adequate excision of the track is carried out." - Bailey & Love "Once an acute episode has resolved, recurrence is common"- Schwartz 9/e p1067 Pilonidal disease Pilonidal disease consists of a hair-containing abscess or chronic sinus, occurring in the intergluteal cleft. It is an acqu...
2
Branching tracts are common
Recurrence is uncommon
Bony involvement is uncommon
Seen in Drivers
Surgery
null
28699c9a-dfdd-43af-9655-4d049f5e9373
single
Which of the following statements are True or False? 1. Genetic polymorphisms of the P450 enzyme system, specifically CYP1A1, or chromosome fragility are associated with the development of lung cancer. 2. Cigarette smoking increases the risk of squamous and small cell lung cancer cell types only. 3. Varenicline-nicotin...
Cigarette smoking increases the risk of all the major lung cancer cell types. Extrathoracic metastatic disease is found at autopsy in >50% of patients with squamous carcinoma. This is an impoant topic for entrance read thoroughly. Ref: Harrisons Principles of Medicine, 18th Edition, Pages 741-42
2
1,2,3 True & 4,5 False
1,3,4 True & 4,5 False
2,4,5 True & 1,3-False
2,5 True & 1,3,4-False
Medicine
null
8185e4ff-3a0e-4f2b-82d5-3238f2eac2da
multi
Barr body is not seen in:
Barr body, or X chromatin Inactive X can be seen in the interphase nucleus as a darkly staining small mass in contact with the nuclear membrane known as the. Number of Barr bodies = number of X chromosome -1 , Turner syndrome patients, number of Barr body = 1-1=0.
2
Klinefelter syndrome
Turner syndrome
Normal female
XXX syndrome
Pathology
Specific Cytogenetic Disorders
5f3ee709-7649-4acf-9ca7-80649551c08e
single
Supracristal plane is above ?
Ans.a. Highest point of iliac crestSupracristal plane is an anatomical transverse plane lying at the upper most pa of the pelvis, the iliac crest.This is usually at the level of the L4 veebrae.It passes through the umbilical region and the left and right lumbar regions.
1
Highest point of iliac crest
Anterior superior iliac spine
Posterior superior iliac spine
Ischeal tuberosity
Anatomy
null
84a8ae9c-3c71-4001-849b-4cc7514597e2
multi
Hyper segmented neutrophils are seen in:
null
1
Megaloblastic anemia
Iron deficiency anemia
Thalassemia
Idiopathic thrombocytopenic purpura
Pathology
null
fbd61cb0-9277-45ee-ba68-feacce4242ae
single
Bilateral upper limb pulse less disease is?
bilateral upper limb pulseless disease is caused by aooaeritis Takayasu's aeritis (also known as, "aoic arch syndrome," "nonspecific aooaeritis," and "pulseless disease) is a form of large vessel granulomatous vasculitis with massive intimal fibrosis and vascular narrowing, most commonly affecting often young or middle...
3
Giant Cell Aeritis
Polyaeritis Nodosa
Aooaeritis
HSP
Medicine
C.V.S
19868e50-1865-4c2f-b246-175a7ce6bda8
single
Biphasic pattern on histology is seen in?
Synovial cell sarcoma can have dual lining of differentiation consisting of epithelial and spindle tumor cells.
3
Osteosarcoma
Osteoclastoma
Synovial cell sarcoma
Rhabdomyosarcoma
Pathology
null
9672d1af-bde0-4019-9aa8-b366b4b7c862
single
Ramla, 65 yrs old male presents with low backpain especially at L3, anaemia and fatiguability) His investigation profile reveals -Hb =7gm%, TLC-9000/cmm, DLC -N- 55%, L-30%, M-10%, E-1%, -2%,Serum proteins-8gm %, ratio-2.9/5.9, ESR-90 and serum creatinine-3.2 mg%. Likely diagnosis is -
null
2
Waldenstroms macroglobulinemia
Multiple myeloma
TB spine
Secondaries in spine
Medicine
null
62adab44-b508-43df-bebb-7c7754ecc8e9
multi
In JVP y descent is absent and X wave is prominent? Thiscsuggests:
Ans. (b) Cardiac tamponadeRef.: Harrison 19th ed. /1573JVP FindingsJVP WavesFindingsConstrictive pericarditisFindingsCardiac tamponadeX waveProminentProminentY waveProminentAbsent
2
Restictive cardiomyopathy
Cardiac tamponade
Constrictive pericarditis
Right Ventricular Failure
Medicine
C.V.S.
5c94af56-0a5e-4cb4-960f-ed2d7fda4f8d
single
Investigation of choice in the early phase of renal transplant
• Vascular complications after renal transplantation are low, presents during the first week after transplantation with sudden pain and swelling at the site of the graft. • Diagnosis is confirmed by Doppler ultrasonography. • Urgent surgical exploration is indicated and, in most cases, transplant nephrectomy is require...
3
IVP
Retrograde cystourethrogram
Ultrasonogram
CT scan
Surgery
null
f45fead1-36e2-4aac-833d-ff1ca0408595
single
A child with complaints of cough. Characteristic 'inspiratory whoop. Sample for investigation is –
"Culture of nasopharyngeal secretion remains the gold standard for diagnosis of whooping cough" - Harrison
1
Nasopharyngeal swab
Tracheal aspiration
Cough plate culture
Sputum culture
Pediatrics
null
bd655a34-39dd-4907-a1ea-81e4c9cd38e6
single
IgA nephropathy is characterised by:-
IgA nephroapthy is also known as Berger nephropathy Gross Hematuria in IgA nephropathy occurs within 1-2 days of onset of an upper respiratory or GI infection (skin infection leads to poststreptococcal glomerulonephritis (PSGN)and not IgA nephropathy). Mild to moderate hypeension can be seen May be associated with loin...
3
Hematuria occur after skin infection
Severe Hypeension
Normal serum levels of C3
Serum IgA levels have a diagnostic value
Pediatrics
Nephritic & Nephrotic Syndrome
c4e44980-8d57-4cd7-aabe-cd2b78cbbedf
single
Which of the listed diseases is most strongly suggested by the above antibody studies? Anti-centromere High titer Anti-Scl-70 Not detected Anti-Pol-I Not detected Anti-RNP Not detected Anti-dsDNA Not detected
Anti-centromere antibodies are a marker for the CREST (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia) variant of scleroderma. The markers for diffuse scleroderma, anti-Scl-70 and anti-Pol-I, are usually negative in CREST syndrome, as are most other autoantibodies. The marke...
1
CREST
Diffuse scleroderma
Mixed connective tissue disease
Sjogren's syndrome
Microbiology
null
5002570b-d43c-456e-a12e-5084e20395ee
multi
Fast breathing in a 3 year old child is?
ANSWER: (C) > 40REF: OP Ghai 7th ed p. 356According to WHO fast respiratory rate:>60/ min< 2 months> 50/min2-12 months>40/min12-60 months
3
> 60
>50
>40
>30
Pediatrics
Disorders of the Respiratory Tract
53a04775-54ca-415c-a1c4-0a44b9a1cfc7
single
Predisposing factor for pneumococal pneumoniaa) CRFb) Lymphoma c) Thalassemiad) Cystic fibrosis
null
1
abc
bc
acd
bcd
Medicine
null
eabe080e-8670-4a18-a4c0-a708fec57ec5
single
Onion skin thickening of aeriolar wall is sees in-
Hyperplastic aeriosclerosis is more typical of severe hypeension. Vessel exhibit onion skin . Concentric laminated thickening of aeriolar walls and luminal narrowing Robbins 9 th edition page no. 334
4
Atherosclerosis
Median calcific sclerosis
Hyaline aeriosclerosis
Hyperplastic aeriosclerosis
Pathology
Cardiovascular system
dc69e381-266b-4828-998b-cae21312deaa
multi
Pupillary reaction to light is still normal in lesion/injury to
Ans. (b) Optic disc* Optic disc is not involved in papillary light reflex.* Pathway of papillary light reflex:Retina - Optic Nerve - Optic Chiasma - Optic Tract - Prerectal Nucleus - Edinger Westphal Nucleus - Inferior Division of 3rd Nerve - Ciliary Ganglion - Short Ciliary Nerves - Sphincter Pupillae
2
Optic nerve
Optic disc
Optic tract
Optic chiasm
Ophthalmology
Diseases of the Optic Nerve
19e0e53b-7d97-40c2-8a62-2ba59cfc8751
single
Centrosome duplication takes place in -
Centrosome duplication is heavily regulated by cell cycle controls. This link between the cell cycle and the centrosome cycle is mediated by cyclin-dependent kinase 2 (Cdk2). There has been ample evidence that Cdk2 is necessary for both DNA replication and centrosome duplication, which are both key events in S phase. I...
3
M phase
GO phase
S phase
G2 phase
Pathology
General pathology
1efb898b-d249-4170-b3ad-003dfd0ea8df
single
Herberdens nodes are seen in:
null
3
Rubella
Rubeola
Osteoarthritis
Typhoid
Medicine
null
c9ccc63e-46e6-4158-984d-4705a7e18d0f
single
In acute tubular necrosis, all are true except
Acute tubular necrosis: - Muddy brown granular or tubular epithelial cell casts- FENa > 1%- UNa > 20 mmol/L- SG < 1.015 Ref: Harrison's 17/e p1757 table 273-2
4
Specific gravity of urine < 1.020
Urine Osmolatlity > 500
Blood urea: creatinine ratio < 20
Urine sodium < 20mmol/l
Medicine
All India exam
4936aa7b-8903-41d7-8816-8e7365f6260a
multi
Which of the following is used in tracking transfer of MS from mother to infant, to detect risk of early childhood caries?
null
2
Albans test
GC-Saliva check SM
Dentocult lactobacilli test
Fosdick calcium dissolution test
Dental
null
855514ec-18ce-4e66-872e-f623581ca15e
single
Coils are incorporated in orthodontic appliances to:
null
2
Decrease the amount of force
Increase the range of movement
Increase flexibility
Increase the amount of force
Dental
null
de979103-43f5-4c50-ab7b-6a8a16215187
single
Differential Cyanosis occurs in which of the following disease:
Ans. D. All of the aboveDifferential cyanosis can be caused by* Persistent pulmonary hypertension of Newborn* Coarctation of Aorta* Interrupted aortic arch
4
Severe coarctation
PPHN
Interrupted aortic arch
All of the above
Pediatrics
C.V.S.
5bdebb79-a8a2-4a74-b15c-d649b4459f49
multi
All drugs are used in Treatment of Mania except -
Drugs used for mania are Lithium, Valproate, Carbamazepine / Oxcarbazepine, Typical & atypical antipsychotics (olanzapine, risperidone, quetiapine, ziprasidone, aripiprazole, haloperidol), benzodiazepines. Trihexylphenidyl is a central anticholinergic drug used in Drug induced Parkinsonism.
2
Haloperidol
Trihexylphenidyl
Lithium
Carbamazepine
Psychiatry
null
eb1bc9fa-4563-44e8-8389-9ef19777a1ab
multi
Which of the following drug is not a uricosuric agent?
Drugs increasing the excretion of uric acid (Uricosuric agents) Probenecid Sulfinpyrazone Benzbromarone Lesinurad
4
Probenecid
Sulfinpyrazone
Benzbromarone
Febuxostat
Pharmacology
Kidney
b9dbbdf1-89d8-4948-aac5-8b0b6993437c
single
The gene that regulates normal morphogenesis during development is :
Ans. is 'b' i.e. Homeobox gene Homeobox geneis associated with normal morphogenesis.Their expression results in the production of localized cellular condensation of primitive mesenchyme in the sites of future bones.They play an important role in patterning of limbs, vertebrae and craniofacial structures.Mutations in Ho...
2
FMR-1 gene
Homeobox gene.
P-16
FTEN.
Pathology
Cytogenetic Disorders
446f9a49-7e0c-4230-bff4-6a8e221bebb7
single
Double-bubble sign in X-ray is seen in
Duodenal atresia
2
Colon carcinoma
Duodenal atresia
Acute pancreatitis
Perforation
Radiology
null
59090ee3-1ac9-4531-87f4-fe99253430ef
single
Card test is done for-
Ans. is 'a' i.e., Plamar interossei * Card Test: This is for palmar interossei (adductors) of the fingers. In this test, the examiner inserts a card between two extended fingers and the patient is asked to hold it as tightly as possible while the examiner tries to pull the card out. The power of adductors can thus be j...
1
Plamar interossei
Dorsal interossei
Abductor pollicis brevis
Palmaris longus
Anatomy
Upper Extremity
97201a22-8d56-4687-8e1f-64e5f06e1ba0
single
Infection of submandibular space is seen in:
(a) Ludwig angina(Ref. Scott Brown, 8th ed., Vol 3; 628; Stell & Maran, 5th ed., 229)Ludwig angina is infection of the submandibular space, i.e. floor of mouth.Vincent angina is ulcerative gingivitis along with involvement of the tonsils.Prinzmetal angina and unstable angina are the acute coronary syndromes.
1
Ludwig angina
Vincent angina
Prinzmetal angina
Unstable angina
ENT
Pharynx
5b6cc3d2-b4c8-4e92-9a10-e6d4f2f0d330
single
High impact resin has?
High impact resin = Butadiene rubber (5 to 10%) in powder
2
Polysterene
Butadine-Styrene rubber
Polyehtyl methacrylate
Polyamides
Dental
null
2680a2dc-cf95-4ef3-a3fb-f6a7d1e073aa
single
A 60-year-old woman complained of weakness, lethargy and easy fatigability. Investigation showed that she had iron deficiency anaemia (Hb. 8 g/dl). She was prescribed cap. ferrous fumarate 300 mg twice daily. She returned after one month with no improvement in symptoms. Her Hb. level was unchanged. On enq...
Gastric acid is required for the absorption of oral iron salts. Concurrent ingestion of antacid tablets could  have interfered with iron  absorption.  Hence,  the  anaemia  failed  to  improve.
1
Lower pH is required for absorption of oral iron salts
Higher pH is required for absorption of oral iron salt
Oral iron can not cross biomembranes in any form
Any of the above can be possible reason.
Pharmacology
null
97cac6f1-7b82-4089-ab2c-c676730e79fd
multi
Contusion usually result from
null
3
Cut injury
Crush injury
Blunt trauma
Penetrating injury
Dental
null
9135dbbf-d0ec-4473-9cfa-05840beaaedb
multi
Pain insensitive structure in brain is:
Choroid plexus Repeat from Al 2009Choroid plexus is pain insensitive structure.Harrison writes-"Relatively .few cranial structures are pain-producing; these include the scalp, middle meningeal aery, dural sinuses, .falx cereberi, and proximal segments of the large pial aeries. The ventricular ependyma, Choroid plexus, ...
4
Falx cerebri
Dural sheath surrounding vascular sinuses
Middle meningeal aery
Choroid plexus
Anatomy
null
78d4a208-75ed-4834-82dc-8fdd5252d060
single
In which phase of sleep, does the bruxism occur?
Bruxism occurs in both stage I and stage II. But more common in stage II. Note: OSA is not associated with a reduction in total sleep time, but individuals with OSA experience a much greater time in stage 1 NREM sleep (from an average of 10% of total sleep to 30–50%) and a marked reduction in slow-wave sleep (stages 3 ...
1
NREM 2
NREM 3
REM sleep
NREM 4
Physiology
null
dee042f1-9be4-474a-8b55-f4b8c702b136
single
80 year old, asymptomatic man present with a Total Leucocyte Count of 1 lakh, with 80% lymphocytes and 20% PMC's. What is the most probable diagnosis?
Answer is C (CLL) : Incidental finding of Lymphocytosis (80,000/mcL) in an elderly and' asymptomatic patient suggests the diagnosis of CLL. Why is CLL the single best answer of choice here ? 'CLL is a disease of older patients wth 90% of cases occurring after the age of 50 years and median age of presentation is 65 yea...
1
HIV
CML
CLL
TB
Medicine
null
a2ab3b4c-82f8-4f10-a71d-f44e696c692e
single
In a patient with cardiac output 5 liters/minute and body surface area 1.7 m2 what will be the cardiac index
A i.e. 3 liters / min/m2
1
3 liter/ min/ m2
4 liter/min/m2
5 liter/ min/ m2
2.5 liter/ mkin/ m2
Physiology
null
c1d8f793-5051-4e27-8a32-476e51c82d31
single