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Investigation of choice in whole-body imaging in metastasis is
Whole body diffusion weighted imaging along with anatomical images such as T1 and T2 can be very useful for the evaluation of malignant tumors/metastasis alternative to PET/CT.The disadvantage is that it is time-consuming investigation The basic principle of DWI is based on the Brownian motion of water molecules which ...
1
MRI
Angiography
Venography
CT scan
Radiology
All India exam
bd08aa97-2254-411c-824f-1da2265f14b0
single
Acute symptomatic sinus bradycardia usually responds to-
Sinus bradycardia: A regular but unusually slow hea beat (50 beats/minute or less at rest). Fainting can occur with sinus bradycardia if the hea slows down even more. This can occur, for example, when the vagus nerve sends a signal to the hea that suddenly drops the hea rate Ref Harrison 20th edition pg 1456
3
Adrenalinea
Dopamine
Atropine
Norepinephrines
Medicine
C.V.S
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Accidental finding of incidentaloma (Adrenal mass) on USG is detected. Following is/are to be ruled out:
Ans is All Widespread use of imaging tests such as abdominal ultrasonography, CT, and magnetic resonance imaging (MRI) is causing increased detections of incidental adrenal masses k/a adrenal incidentalomas . The below given table lists the most common histologic types of adrenal incidentalomas: Causes of adrenal incid...
4
Cushing's disease
Metastasis
Adrenal adenoma
All
Surgery
null
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multi
For open pneumothorax which of the following is of choice
"Open Pneumothorax is one in which full thickness segment of the chest wall has been destroyed and the negative intrapleural pressure sucks air directly through the chest wall defect rather than through the trachea into the alveoli. It occurs most commonly after shotgun blasts explosion with flying debris. The pt. is s...
2
IPPV
ICD with underwater seal
Thoracotomy and close the rent
Wait and watch
Anatomy
Cardio thoracic surgery
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The bacterial drug resistance in tuberculosis results from
Refer Katzung 11/e p824 Resistance to INH occurs due to point mutation in inhA gene Resistance to Rifampicin occurs due to point mutation in rpoB gene Resistance to Ethambutol is due to mutation resulting in over expression of embB gene
4
Transduction
Transformation
Plasmid method
Mutation
Pharmacology
Chemotherapy
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single
The most common retrobulbar orbital mass in adults -
Commonest benign orbital tumor among adults with female preponderance(70%) ,is located in the retrobulbar muscle cone Ref: ak khurana 6th edition
3
Nerurofibroma
Meningioma
Cavernous haemangioma
Schwannoma
Ophthalmology
Tumors
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Aspirin irreversibly inhibits the following enzyme in the formation of eicosanoids:
Ans. B. CyclooxygenaseCyclooxygenase is required for the synthesis of prostaglandins by arachidonic acid. Aspirin, indomethacin, brufen, phenyl butazone and other NSAIDS inhibits COX (Cyclooxygenase). Aspirin inhibits COX of both PGHS-1 and PGHS-2 by acetylation
2
Lipoxygenase
Cyclooxygenase
Phospholipase-A2
Peroxidase
Biochemistry
Enzymes
36c32315-fe6d-4482-9dd3-636d2d416234
single
A child wakes up at night sweating and terrified does not remember the episode. Diagnosis ?
Sleep terrors/ Night Terrors individual gets up from sleep with a panicky scream and intense anxiety, body motility and autonomic hyperactivity. individual ahs limited recall of the event. Ref: synopsis of psychiatry, 11e, pg 539.
3
Narcolepsy
Nightmares
Night terrors
Somnambulism
Psychiatry
Sleep disorders and eating disorders
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Sirolimus is administered by which route?
Sirolimus is available only as an oral drug. Its half-life is about 60 hours, while that of everolimus is around 43 hours. Ref: Katzung 11th edition Chapter 61.
1
Oral
Inhalation
Intranasal
Intravenous
Pharmacology
null
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All of the following is true about Mullerain Agenesis except :
A condition where the mullerian duct is not formed and hence its derivates like vagina,uterus and tubes are not made. Ovary is spared because it is formed from the genital ridge. Mayer Rokitansky Kuster Hauser (MRHK) syndrome Also k/a Mullerian agenesis Occurs in 1:5000-1:20,000 women Features include Primary amenorrho...
3
Paial or complete absence of vagina
Wide array of uterine abnormalities
Wide array of ovarian abnormalities
Normal 46 XX karyotype
Gynaecology & Obstetrics
Mullerian Abnormalities
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Relative risk is represented by -
Ans. is 'a' i.e., Incidence among exposed/incidence among nonexposed Relative risk (risk ratio)o Relative risk is the ratio of the incidence of the disease (or death) among exposed and the incidence among nonexposed.Incidence of disease amone exposedRR =----------------------------------------------------------------In...
1
Incidence among exposed/incidence among non-exposed
Incidence among non-exposed1'incidence among exposed
Incidence in exposed minus incidence in non-exposed
None of the above
Social & Preventive Medicine
Analytical Epidemiology
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multi
Function of thyroid hormones:
Ans: A (Inhibits beta myosin heavy chain) Ref: Pal GK, The Thyroid Gland, In: Textbook of Medical Physiology, 2nd ed, Ahuja Publishing House 2011: 46: 352-55Explanation:Physiological Actions of Thyroid HormoneBasal metabolism| rate of oxygen consumption| Na+ K+ ATPase activityThermogenic actionOn nervous systemProlifer...
1
Inhibits beta myosin heavy chain
Increases cholesterol
Inhibits ovulation
Increases diastolic blood pressure
Physiology
Endocrinology metabolism
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Von Hippel Landau Syndrome is associated with which type of renal neoplasm?
Ans: A (Renal clear cell carcinoma) Ref: Campbell Walsh Urology, 10th edition. 2011, Page 1426Explanation: (See table below)Site of origin:Proximal tubule-Conventional (clear cell) RCC and papillary RCCDistal tubule - OncocytomasCollecting duct - Chromophobic and collecting duct RCCCalyceal epithelium near renal papill...
1
Renal clear cell carcinoma
Angiomvolipoma
Papillary renal cell carcinoma
Renal medullary carcinoma
Surgery
Renal Tumors
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Most common ovarian tumour in pregnancy is:
null
2
Mucinous cyst adenoma
Dermoid cyst
Metastasis
Dysgerminoma
Gynaecology & Obstetrics
null
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Tl-weighted axial gadolinium-enhanced MRI demonstrates an enhancing tumor of the right frontal lobe. The most likely diagnosis is
(D) Glioblastoma multiforme# On MRI, the tumors appear as ring-enhancing masses with central necrosis and surrounding edema.> Glioblastoma multiforme (GBM; malignant glioma) is the highest-grade form of astrocytoma and makes up about two thirds of all brain astrocytomas.> Prognosis for this tumor is at the extreme wors...
4
Oligodendroglioma
Ependymoma
PCNSL
Glioblastoma multiforme
Psychiatry
Miscellaneous
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"Window" of the limbic system through which it sees the external world is:
Amygdala has been called the "window" through which the limbic system sees the place of the person in the world because it receives neuronal signals from all poions of the limbic coex, as well as from the neocoex of the temporal, parietal, and occipital lobes, especially from the auditory and visual association areas.
2
Hypothalamus
Amygdala
Hippocampus
Thalamus
Physiology
Higher Functions
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Which of the following is not true of non depolarizing skeletal muscle relaxants?
Fasciculations are shown by depolarizing muscle relaxants. These agents do not cause hypothermia but their effect may be prolonged in hypothermia. KD Tripathi 8th ed.
3
Causes histamine release
Hypothermia prolongs their effect
Fasciculations of muscle
Ganglion blockade
Pharmacology
All India exam
381aa792-081d-4633-8040-b19e60222b91
multi
Nigro protocol is for which carcinoma
Nigro protocol or Nigro Regime for Anal Carcinoma (Norman Nigro, et al 1974):  * Initial radiotherapy for 3 weeks 3000 rads (30 Gy total) to perineum and pelvis  * Then chemotherapy--5 FU, for 4-5 days; is a radiosensitizer, staed on 1st day of as 1000 mg/m2 continuous infusion. Mitomycin C is 15 mg/m2 as single dose...
1
Anal
Colon
Hepatocellular
Pancreatic
Surgery
Urology
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Glycosaminoglycans located in CNS is
Proteoglycans linked to chondroitin sulfate by the Xyl-Ser O-glycosidic bond are prominent components of cailage. They are located at sites of calcification in endochondral bone and are a major component of cailage. They are found in high amounts in the ECM of the central nervous system and, in addition to their struct...
2
Hyaluronic acid
Chondroitin sulfate
Keratan sulfate 2
Heparan sulfate
Biochemistry
Metabolism of carbohydrate
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Bullet which is left inside the body for long is referred to as ?
Ans. is 'a' i.e., Souvenir bullet Projectile is an object propelled by force of rapidly burning gases. In shotgun these are lead shots and pellets (recently steel is also used instead of lead) and in rifled weapons (pistal, rifle, revolver), these are bullets. Tip of the bullet is knwon as nose. Varieties of bullets ar...
1
Souvenir bullet
Tracer bullet
Tumbling bullet
Tandem bullet
Forensic Medicine
null
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single
which pa of sperm helps in penetration of zona pellucida ?
Acrosome have acrosin enzyme which helps in penetration. Mitochondria is present in middle pa.
4
head
middle piece
neck
acrosome
Anatomy
Systemic histology
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single
In which of the following conditions parakeratosis most frequently occur?
Parakeratosis is defined as retention of keratinocyte nuclei within the horny layer cell layer. It can occur in condition with increased epidermal cell turnover or with inflammatory changes in epidermis. Dysplastic epithelial changes such as those occurring in actinic keratoses and Bowens disease are normally accompani...
1
Actinic keratoses
Basal cell carcinoma
Seborrheic keratoses
Molluscum contagiosum
Skin
null
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single
Which of the following statement regarding normal microbial flora present on the skin and mucous membranes is true?
Normal microbial flora are more or less constant for each species and are broadly classified as residents and transients. Residents constitute a constant population which cannot be completely removed permanently, while transient organisms vary from time to time and are not permanent. Antimicrobials cannot remove the no...
1
It cannot be eradicated by antimicrobial agents
It is absent in the stomach due to the acidic pH
It establishes in the body only after the neonatal period
It does not have any protective functions
Microbiology
null
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multi
Which of the following is related to occipital anchorage
null
3
Intra oral force
Tipping a tooth
Extra oral force
Bodily movement of anchor
Dental
null
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Forceps inside the abdomen postoperatively amounts to
Res ipsa loquitur (Latin for "the thing speaks for itself"): * Doctrine that infers negligence from the very nature of an accident or injury itself proves the negligent action of the physician in the absence of direct evidence. Res Judicata * Medical negligence case adjudicated by a cou and therefore may not be pursued...
1
Res ipsa loquitur
Res judicata
Respondent superior
Novus actus interveniens
Forensic Medicine
Medical Jurisprudence
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The crystalline lens derives its nourishment from -
The crystalline lens, being avascular structure is dependent for its metabolism on chemical exchanges with the aqueous humour. Some nutrition is also derived from the vitreous humour, but it is much less than that derived from aqueous humour.
3
Blood vessels
Connective tissue
Aqueous and vitreous
Zonules
Ophthalmology
Lens
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Epiglottitis in a 2-year-old child is diagnosed. Among the following options, most commonly Epiglottitis occurs due to infection with:
Ans. is 'c' i.e., Hemophilus influenza From the above given long list of references it must be evident, that this one was tough for us. is H. influenzae still the most common etiological agent of epiglottitis or has it receded back giving place to other agents such as Streptococcus? Harrison, 16/e and Nelson, 17/e, say...
3
Influenza virus
Staphylococcus aureus
Hemophilus influenzae
Respiratory syncytial virus
Pediatrics
Disorders of the Respiratory Tract
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Q fever is caused by-
Ans. is 'b' i.e., C. burnetii DiseaseAgentInsect vectorMammalian reservoir1. Typhus group a. Epidemic typhusR. prowazekiiLouseHumansb. Murine typhus (Endemic typhus)R. typhiFleaRodentsc. Scrub typhusR. tsutsugamushiMiteRodents2. Spotted fever group a. Indian tick typhusR.conoriiTickRodents, dogsb. Rocky mountain spotte...
2
R Quintana
C. burnetii
R typhi
R akari
Social & Preventive Medicine
Communicable Diseases
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Which of the following inhibits GH secretion from the anterior pituitary gland?
Growth hormone, also known as somatotropin, is secreted by somatotroph cells, which account for 50% of the anterior pituitary glands. The release of growth hormone from the anterior pituitary is pulsatile in nature, increasing after meals: with exercise, and during slow-wave sleep. Growth hormone, which is necessary fo...
1
Somatostatin
Growth hormone- releasing hormone (GHRH)
Hypoglycemia
Arginine
Medicine
C.N.S
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single
Which of the following is the treatment of choice for cryptococcal meningitis ?
null
4
Fluconazole
Itraconazole
Flucytosine
Amphotericin B
Pharmacology
null
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single
Conjugation does not involve -
Conjugation: it is the process whereby a male or donor bacterium mates or makes physical contact with a female or recipient bacterium and transfer genetic material into it. This has been considered to be the bacterial equivalent of sexual mating in higher organisms but the analogy is irrelevant as following conjugation...
1
Bacteriophages
HFr
Fr
Plasmids
Microbiology
general microbiology
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A 40-year-old hypeensive lady is brought to the emergency room after being unresponsive following a sudden bout of severe headache, vomiting and neck rigidity at work. 0/E her BP is 180/100 mmHg and her respiration is irregular and of Cheyne-Stokes type. She is agitated and doesn't follow commands, but moves her extrem...
Ans. Subarachnoid hemorrhage due to rupture cerebral aneurysm
1
Subarachnoid hemorrhage due to rupture cerebral aneurysm
Hypoglycemic coma
Conversion reaction
Addisonian crisis
Forensic Medicine
null
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Atheromatous changes of blood vessels affects early in
repeated question The risk factors are Constitutional- genetic abnormalities,family history , increasing age, male gender, hyperlipidemia,hypeension,cigaratte smoking, diabetes, inflammation Myocardial infarction is the main condition
2
Kidney
Hea
Liver
Spleen
Pathology
Cardiovascular system
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single
Which of the following drugs can be safely prescribed in pregnancy -
For pregnant women and women who have given bih, heparin is the anticoagulant of choice and is recommended by the Royal College of Obstetricians and Gynaecologists. It does not cross the placenta, and therefore is considered to be safe . Ref - Harrisons 20e p848-850
3
Warfarin
ACE inhibitors
Heparin
Beta-blockers
Medicine
Miscellaneous
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The preferred agent in treatment of typical B cell CLL among elderly patients is:
Typical B cell CLL/small lymphocytic lymphoma treatment: The most common treatments for patients with typical B cell CLL/small lymphocytic lymphoma have been chlorambucil or fludarabine. Chlorambucil is the preferred agent in elderly patients. Chlorambucil can be administered orally while fludarabine is administered IV...
2
Fludarabine
Chlorambucil
Cyclophosphamide
Bendamustine
Medicine
null
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single
Obermeyer test comes out to be positive in which disease
Amino acid Trytophan gives obermeyer test positive. Hartnup's disease is characterised by impaired absorption of neutral amino acids especially tryptophan. Thus Tryptophan gets excreted in large amounts and gives positive obermeyer test.
1
Hartnup's disease
Phenylketonuria
Alkaptonuria
Pellagra
Biochemistry
null
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single
Somites are derived from ----- mesoderm
The intraembryonic mesoderm splits into:Paraxial which forms SomitesIntermediate plate gives rise to the Genital & Urinary systemLateral plate encloses a cavity called the intraembryonic coelom, which fuher forms the pericardial, peritoneal & pleural cavities
3
Intermediate plate
Lateral plate
Paraxial
Extraembryonic
Microbiology
All India exam
e1f5f86a-d8a5-49a4-8d1c-b4bcf2c6f0e7
single
In AIDS , lymphadenopathy is most often due to -
Persistent Generalized Lymphadenopathy HIV patients develop PGL as an early clinical manifestation of HIV infection PGL is defined as presence of >1LN in two or three extra-inguinal sites for >3 months without an obvious cause Enlargement is due to follicular hyperplasia Ref: Harrison's 19th edition Pgno :1232-1233
2
Lymphoma
Non specific enlargement of lymph nodes
TB
Kasposi's sarcoma
Anatomy
General anatomy
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The differentiation of the Gonad into Male is dependent on:
null
1
Presence of SRY gene
Lack of SRY gene
Presence of AMH
Presence of Testosterones
Gynaecology & Obstetrics
Intersex
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A 63-year-old patient presents with a lesion on his toe that has doubled in size in the past year. It is non-tender and does not bleed, but his wife says it's getting bigger and darker on one side. The macule is 7mm in diameter. Which of the following is the best next step?
Any pigmented cutaneous lesion that has changed in size or shape or has other features suggestive of Malignant melanoma is a candidate for biopsy. An excisional biopsy with 1-3 mm margin is suggested. Accurate measurement of thickness, if the lesion is melanoma, and constitutes definitive treatment if lesion is benign....
1
Excisional biopsy
Topical imiquimod cream
Liquid nitrogen cryotherapy
Reassurance and observation
Dental
Tumours of skin
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Which of the following causes increased rennin on prolonged use ?
Ans. is 'b i.e., Enalapril
2
Clonidine
Enalapril
Methyldopa
Blocker
Pharmacology
null
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Grid is a device used for -
X ray grid ensures the contrast of image on X ray film. X ray grid absorbs the scattered xrays and filters out radiations
1
Reducing scattered radiation
Reducing patient's exposure time
Reducing the contrast of the X-ray
All of the above
Radiology
Fundamentals in Radiology
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True statement regarding fracture base of the skull are all of the following except: March 2008
Ans. C: Early surgery is indicated for optimal outcome
3
Prophylactic antibiotics are usually not required
Associated with 8 cranial nerve palsy
Early surgery is indicated for optimal outcome
May present with CSF otorrhoea
Surgery
null
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multi
Penicillin would be LEAST effective in treating:
Mycoplasma organisms do have a cell wall and are therefore resistant to penicillin. Other forms of bacteria that lack a cell wall are spheroplasts and protoplasts, which are formed from gram-negative and gram-positive bacteria, respectively, through the action of penicillin or by other procedures that remove the cell w...
4
Syphilis
Streptococcal pharyngitis
Pneumococcal pneumonia
Mycoplasma pneumonia
Microbiology
null
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Which pa is high sensitive to radioactivity:
Radio sensitivity of different cells or tissues: White blood cells (lymphocytes) Red blood cells (erythrocytes) Immature reproductive cells Epithelial cells Endothelial cells Connective tissue cells Bone cells Nerve cells Brain cells Muscle Ceells
2
Adult bone
Growing skin
Pancreas
CNS
Radiology
DNB 2018
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Nitroglycerine causes all, EXCEPT:
Nitroglycerin is predominantly a venodilator. With large doses of NTG, a significant fall in blood pressure and a reflux sympathetic activation resulting in tachycardia occurs. Ref: KDT 6th Edition, Page 523; Essentials of Medical Pharmacology By K D Tripathi, 5th Edition, Pages 488-90
1
Hypotension and Bradycardia
Methamoglobinemia
Hypotension and Tachycardia
Vasodilatation
Pharmacology
null
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Antischkow cells are -
Ans. is 'a' i.e., Modified macrophages Pathologic Features of Acute Rheumatic Fever :-o Aschoff bodies focal inflammatory lesions seen in acute rheumatic fever consisting of foci of T lymphocytes, occasional plasma cells, and plump activated macrophages,o These activated macrophages called Anitschkow cells (pathognomon...
1
Modified macrophages
Modified neutrophils
Modified B cells
Modified RBCs
Pathology
Rheumatic Fever
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Artemesinin is best used for
Treatment of cerebral malaria: IV Quinine: Needs continuous cardiac monitoring; can cause QTc prolongation, hypoglycemia IV Artesunate has better efficacy and safer than quinine, 2.4 mg/kg IV BD. then OD Exchange transfusion if parasite index is > 10% Artemisinin (qinghaosu) acts rapidly against erythrocytic stages of...
3
Relapse of malaria
Chronic malaria
Cerebral malaria
Recrudescent malaria
Medicine
null
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What one structural feature do all blood capillaries have in common -
Ans. is None The blood flows from the hea through aery, aeriole, capillary, venule and vein, and then returns to the hea. Structure of aery and aeriole o It is made up three layers ? Tunica Intima o The inner most layer (towards lumen) of aery is intima. o It consists of endothelial cells which rest on basment membrane...
4
Absence of intracellular fenestrations in the endothelial cells
Presence of intracellular fenestrations
A discontinuous basement membrane
null
Pathology
null
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Which of the following condition has a propensity to invade the poal or hepatic vein?
Hepatocellular carcinoma has a propensity to invade poal or hepatic veins. Neo vascularity within the thrombus in the poal or hepatic veins on Doppler US is considered diagnostic of hepatocellular carcinoma. Common factors associated with increased risk of developing HCC: Cirrhosis from any cause Hepatitis B or C chron...
2
Cavernous hemangioma
Hepatocellular carcinoma
Focal nodular hyperplasia
Hepatic adenoma
Surgery
null
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Which of the following malignancy is associated with underlying progression and spreads characteristically in a stepwise fashion and hence staging the diseaseis an impoant prognostic factor?
Ans. is `a' i.e., Hodgkin's lymphomao Hodgkin's lymphoma encampasses a distinctive group of neoplasms that arise almost invariably in a single lymph node or chain of lymph nodes and spread characteristically in a stepwise fashion to the anatomically contiguous nodes.o Therefore staging of Hodgkin's lymphoma not only de...
1
Hodgkin's lymphoma
Multiple myeloma
Mature T cell NHL
Mature B cell NHL
Pathology
null
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Methylation of deoxyuridylate to thymidylate involve one carbon metabolism. Cofactor in one carbon metabolism is:
FH4 is an intermediate in reactions involving the transfer of one-carbon units from a donor to an acceptor. One-carbon units enter the folate pool principally the serine hydroxymethyltransferase reaction which requires pyridoxal phosphate as cofactor. The most impoant clinically is the methylation of deoxyuridylate to ...
1
Folic acid
Thiamine
Pyridoxine
Riboflavin
Biochemistry
null
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All of the following organizations have their head quarter at Geneva EXCEPT:
Ans. a (UNICEF). (Ref. Park PSM 22nd/pg. 862)UNICEF (UNITED NATIONS INTERNATIONAL CHILDREN EDUCATION FOUNDATION)# Established in 1946# Regional office -Delhi# Head quarter -Newyork# Contents of child health (UNICEF) =- Child health- Child nutrition- Family and child welfare- Education# Currently UNICEF is promoting a c...
1
UNICEF
WHO
ILO
null
Social & Preventive Medicine
Healthcare of the Community & International Health
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Febrile response in CNS is mediated by
ref Harrison 18/e 143p -145 Fever is produced in response to substance called pyrogens that acts by stimulating prostaglandins synthesis in vascular and periferal cells of hypothalamus.there are exogenous and endogenous pyogens
1
Bacterial toxin
IL1
IL6
Interferon
Anatomy
General anatomy
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single
Frequency of sterilization services at different health facilities at "Fixed day static services (FDS)" is given below. Find out the wrong one:
In District hospital sterilization is done weekly. Govt. of India is promoting FDS approach in sterilization services within public health system with the aim of increasing access to sterilization services. Ref: Park's textbook of Preventive and Social Medicine, 21st edition, page-475
1
District hospital - daily
Sub-district hospital - weekly
CHC/ Block PHC - fonightly
24*7 PHC/ PHC - monthly
Social & Preventive Medicine
null
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single
A normal healthy child has a height of 100 cm and weighs 16 kg. What is his most likely age ?
null
2
3 years
4 years
5 years
6 years
Pediatrics
null
78b90890-c775-4092-8261-1c65d5a4552c
single
Study state plasma concentration is achieved after?
Ans. is 'd' i.e., 5 t%
4
2 t1/2
3 t1/2
4 t1/2
5 t1/2
Pharmacology
null
8335fba2-2f41-4faa-89d0-856ca61401ef
single
Tender hepatomegaly is seen in all except?
Tender hepatomegaly * CHF (acute) * Viral hepatitis * Amoebic liver abscess Reye syndrome - Anicteric hepatitis with combination of Aspirin + V. Zoster
4
CHF (Acute)
Viral hepatitis
Amoebic liver abscess
Reye syndrome
Medicine
Hepatitis
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multi
Which of the following is false regarding suspended animation?
Ans. is 'd' i.e., It usually lasts for 6 hrs Suspended animation (sudden death) It is apparent death, i.e. signs of life are not found as the functions are interrupted for some time or are reduced to minimum. The person is not dead i.e. there is no somatic death, brain death or molecular (cellular) death. Life continue...
4
Can be produced voluntarily
Patient can be resuscitated
It is state of apparent death
It usually lasts for 6 hours
Forensic Medicine
null
24e3f054-77c7-4b90-b200-76ca21c1c0ab
multi
Anticancer drug with disulfuram like action -
Ans. is 'a' i.e., Procarbazine Disulfiram like reaction Ceain drugs when taken concurrently with alcohol produce disulfiram like actions. That means these drugs produce similar distressing symptoms as disulfiram, when taken with alcohol - flushing, burning sensation, throbbing headache, prespiration, unesasiness, tight...
1
Procarbazine
Nitrosurea
5 FU
Methotrexate
Pharmacology
null
e9450913-6b7a-46da-b758-bb45def9a060
single
A middle aged female presented with a 4cm mass in upper outer quadrant of the breast. Biopsy showed densely packed cells within large lakes of mucin. Which of the following is the most likely diagnosis of this patient?
Colloid (mucinous) carcinoma is an invasive variant. Colloid carcinoma has a glistening surface and mucoid consistencyon cut section Composed ofsmall clusters of epithelial cells,occasionally forming glands,floating in pools of extracellular mucin. In its pure form,colloid carcinomahas a considerablybetter prognosistha...
2
Medullary carcinoma of breast
Colloid carcinoma of breast
Tubular carcinoma of breast
Papillary carcinoma of breast
Pathology
NEET Jan 2020
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single
The sulphonylurea with relative longer duration of action is:
The duration of action of various sulfonylureas is given below: Tolbutamide: 6-8 hours Glipizide: 10-16 hours Glibenclamide: 16-24 hours Chlorpropamide: 30-36 hours
1
Chlorpropamide
Tolbutamide
Glibenclamide
Glipizide
Pharmacology
null
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single
Heriditory spherocytosis is caused by
Spectrin causes membrane loss leading to spherical shape of rbc
1
Spectrin deficiency
Hb deficiency
Incresed sodium levels
Increased calcium levels
Anatomy
General anatomy
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single
Main pa of pulmonary aery is a derivative of which of the following branchial arch?
The ventral pa of the 6th arch forms the main pa of the pulmonary aery. The dorsal pa on the left side persist as ductus aeriosus which closes after bih and remains as ligamentum aeriosum. The dorsal pa on the right side disappears. Vascular elements of branchial arches:First arch: Maxillary aerySecond arch: Stapedial ...
4
2nd arch
3rd arch
4th arch
6th arch
Anatomy
null
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single
55 year old male patient who is a know case of chronic kidney disease present to emergency with vomiting and Is diagnosed with uremic acidosis. His ABG analysis report is pH= 7.42 pCO2= 40 HCO3= 25 Na+= 140 mmol/L K+= 3 mmol/L Cl-= 95 mmol/L
PH is higher, but CO2 and HCO3 look normal. So look at Anion gap = 20 . But difference in HCO3 = 0  so is a case of High Anion Gap metabolic acidosis + metabolic alkalosis.
3
Respiratory acidosis
Respiratory Alkalosis
High Anion Gap metabolic acidosis + metabolic alkalosis
High Anion Gap metabolic acidosis + Respiratory Alkalosis
Medicine
null
39c325f4-b6f7-4544-ba54-0a1891b74c49
single
Which is not a side effect of POP
Adverse effects of progestin only pill (minipill) Menstural irregularities Headache, nausea, dizziners Bloating or weight gain Increased risk of INDDM Ovarian cysts Breast tenderness Acne Ectopic pregnancy Ref : Shaw book of gynecology 8th Ed
2
Ovarian cysts
Venous thromboembolism
Increased risk of diabetes mellitus
Ectopic pregnancy
Gynaecology & Obstetrics
All India exam
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single
Tense bullous lesions are seen in -
In bullous pemphigoid, there will be large, tense, oval or round blisters arise on normal or erythematous skin which may contain serous or hemorrhagic fluid. Page no.283. Reference IADVL's concise textbook of dermatology
3
Pemphigus vulgaris
Pemphigus foliaceous
Bu11ous pemphigoid
Pemphigus vegetans
Dental
Vestibulobullous disorders
3717fae3-6056-4fdf-a40b-d413ea5e47db
single
Colonic divericulosis and diverticulitis maximally seen in:
Ans. (a) Sigmoid colonRef: Sabiston 20th edition, Page 1333Acquired diverticulum:* Most common site in colon -- sigmoid* Most common site in small intestine -- duodenum
1
Sigmoid colon
Rectum
Transverse colon
Ascending colon
Surgery
Small & Large Intestine
f7973e2c-db32-4532-86d0-97f514af2409
multi
Proximal & distal renal tubular acidosis is differentiated by all except -
null
2
Stones in kidney
Hypokalemia
Daily acid secretion
Presence of Fanconi syndrome
Medicine
null
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multi
The major pressures that determine filtration and absorption of fluid by capillaries are the:
Ans. A. Capillary hydrostatic pressure and plasma colloid osmotic pressureAll The other possibilities include one minor force for filtration or absorption.
1
Capillary hydrostatic pressure and plasma colloid osmotic pressure
Plasma colloid osmotic pressure and interstitial hydrostatic pressure
Interstitial hydrostatic pressure and tissue colloid osmotic pressure
Capillary hydrostatic pressure and tissue colloid osmotic pressure
Physiology
Kidneys and Body Fluids
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single
Suprasellar aneurysms causes
(B) Bitemporal hemianopia # Sagittal (central) lesions of the chiasma.These are characterized by bitemporal hemianopia and bitemporal hemianopic paralysis of pupillary reflexes.> Lateral chiasmal lesions: Salient features of such lesions are binasal hemianopia associated with binasal hemianopic paralysis of the pupilla...
2
Binasal hemianopia
Bitemporal hemianopia
Homonymous hemianopia
Congruous homonymous hemianopia
Medicine
Miscellaneous
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single
Which of the following statements about pneumothorax is true:
Answer is D (Often need chest tube inseion): Pneumothorax is associated with decreased breath sounds, hyperresonant (increased) percussion note. Chest tube drainage is often required but is not necessary in all cases. Many small pneumothoraces resolve spontaneously as air is reabsorbed from the pleural space. In reliab...
4
Breath sounds are increased
Percussion note is decreased
Always needs chest tube inseion
Often needs chest tube inseion
Medicine
null
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multi
Circumferential clasp is
null
1
Aker's clasp
Retentive arm Lies at the occlusal third
Clasp can be easily adjusted
Encircles the tooth from the point of origin
Dental
null
6069fec7-5c7e-4c83-97ae-bd70ae101037
single
Hepatitis C virus TRUE finding is -a) Spreads along fecooral routeb) Antibody to HCV may not be seen in acute stagec) Does not cause chronic hepatitisd) It cannot be cultured
Two choices are correct in this Question : Antibody to HCV may not be seen in Acute stage "Antibody to HCV appears late and irregular, limiting their diagnostic utility" it cannot be cultured “HCV cannot cultured It can only be cloned in E. coli" Modes of transmission of HCV Blood transfusion, through contaminated bloo...
1
bd
d
ab
ac
Microbiology
null
143cc470-aa4f-44e2-883d-6197719ecd87
multi
Kallu 2 yrs child weighing 6.7 Kg presents in the casualty with history of vomiting & diarrohea for last 2 days. On examination skin pinch over the ant. abdominal wall go quickly to its original position. Interpretation of skin - pinch test in this child will be-
Ans. is 'd' i.e., Skin Pinch can't be evaluated in this child Frist step in assessing the skin pinch requires status of malnutrition of child as skin pinch is less useful in infants or children with Marasmus (severe wasting), Kwashiorker (Severe malnutrition with edema), Obese children Child in the given question is 2 ...
4
No dehydration
Some dehydration
Sever dehydration
Skin pinch can not be evaluated in this child
Pediatrics
null
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multi
A patient presented with blunt trauma to the abdomen to the emergency department. His heart rate is 150/min and his BP is 80/50 mm Hg. He is scheduled to undergo an emergency laparotomy. Which of the following is the anaesthetic agent of choice ?
Inducing agents of choice patients with hypotension are Ketamine and Etomidate :- (1) If the patient is hypertensive at the time of induction → Etomidate is preferable. (2) If the patient is normotensive or mild hypotensive → Either of two can be used. (3) If the patient is severely hypotensive → Ketamine is preferred.
3
Thiopentone
Midazolam
Ketamine
Propofol
Anaesthesia
null
7fb9025b-6880-4f7c-85aa-530d61a77569
single
False statement about trigeminal nerve is
Trigeminal nerve has 4 nuclear which are main sensory nucleus (carrying sensation from face & anterior scalp motor nucleus (supplying muscles of mastication, tensor tympani /palatini, mylohyoid & digastric anterior belly), mesencephalic nucleus and spinal nucleus (extending in medulla oblongata & spinal cord upto C2 se...
3
Caries sensation from face and scalp
Has motor branch
Arise from C8 nerve root
Composed of spinal nucleus
Anatomy
null
fb6c9728-0481-47cc-9bbd-71cb5c3686b5
multi
Macrophages with abundant cytoplasm containing dusty brown pigment are seen in
Desquamative interstitial pneumonia is characterized by large collections of macrophages in the airspaces in a current or former smoker. The macrophages were originally thought to be desquamated pneumocytes, thus the misnomer "desquamative interstitial pneumonia."The most striking finding is the accumulation of a large...
1
Desquamative Interstitial Pneumonia
Pulmonary Alveolar Proteinosis
Pulmonary Langerhans Cell Histiocytosis
Pulmonary Eosinophilia
Pathology
Respiratory system
38c4b14e-f6f6-4bfb-8b04-04d949be6156
single
Most common cause of death due to measles is
null
2
Pneumonia
Secondary bacterial infection
Measles encephalitis
Otitis media
Social & Preventive Medicine
null
8dc21618-1e70-4baa-b03e-86db8f05eb5e
single
All of the following statements about carcinoid syndrome are true except:
Answer is C (Metastasis to bone is common in Midgut Carcinoids): Palliative Care (Oxford University Press, 2009)/ 452; Multiple references Metastasis to bone is rare in Midgut Carcinoids and is Common in Foregut Carcinoids. Features Foregut Midgut Hindgut Site Esophagus Jejunum Transverse Colon(Distal) Stomach Ileum De...
3
Midgut carcinoids produce typical carcinoid syndrome
Plasma serotonin levels may be normal in atypical carcinoid syndrome
Metastasis to bone is common in Midgut Carcinoids
Carcinoid Syndrome is rare in Hindgut Carcinoids
Medicine
null
d90d9b76-fc95-4f1e-9625-578dd48027d6
multi
cleft palate is the side effect of
- SIDE EFFECTS OF THE DRUG - APLASTIC ANEMIA - AGRANULOCYTOSIS - Hyponatremia - Steven Johnson's syndrome - Liver enzyme elevation - It has teratogenic potential - CLEFT PALATE, FINGER NAIL HYPOLASIA, - SPINA BIFIDA Ref, kaplon and sadock, synopsis of psychiatry, 11 th edition,pg no.935
1
carbamezepine
clozapine
risperidone
olanzapine
Anatomy
Pharmacotherapy in psychiatry
1c5d91d8-3a19-4ce8-b54e-03b163bf8867
single
Features of pulmonary venous hypertension are A/E–
Radiological findings of PVIER :- Prominent upper lobe vessels (due to diversion of blood to upper lobe veins), cephalization of pulmonary vascularity, peribronchial cuffing, Kerley B lines (due to interlobar septal thickening), Perihilar haze, Alveolar edema, pleural effusion, Ground glass appearance of lung, Pulmonar...
4
Perihilar haze
Peribroncheal cuffing
Upper lobar diversion
Uniformly branching lines parallel to pleura
Radiology
null
7aaa1d2d-28f9-4fdc-86ea-97729a0c747e
multi
A child with bladder exstrophy and chronic renal failure. The Anaesthesia of choice for the child while operating exstrophy is –
"Atracurium and cisatracurium are muscle relaxants of choice for both liver and kidney failure".
1
Atracurium
Mivacurium
Pancuronium
Rocuronium
Anaesthesia
null
1731048d-1f5c-4647-be1d-9ff1507b1459
single
Melphalan is used in -
Ans. is 'a' i.e., Multiple myeloma o Melphalan is an anticancer (alkylating) agent which is most effective in multiple myeloma.
1
Multiple myeloma
Wilm's tumour
Neuroblastoma
Retinoblastoma
Pharmacology
null
9105fa8d-a25e-46e0-87d4-b8e40109bd4a
single
The liver biopsy in acute hepatitis due to hepatitis B virus is likely to show all of the following, except ?
Ans. is 'b' i.e., Ground glass hepatocytesGround glass hepatocytes are large hepatocytes containing surface antigen. Their cytoplasm is ground glass in appearanceo These cells are seen in chronic hepatitis (not acute hepatitis)o Ground glass hepatocytes can be identified histochemically with orcein or aldehyde fuschin ...
2
Ballooning change of hepatocytes
Ground glass hepatocytes
Focal or spotty necrosis
Acidophil bodies
Pathology
null
668e422c-b4f0-4c1b-95a2-d5f3b6f3ace3
multi
The type of fracture occur by fall from height on the feet or buttock is
Ring fracture It is a fissured fracture which encircles the foramen magnum. This type of fracture may occur by fall from a height on the feet or buttock A heavy blow on the top of head may also cause a ring fracture. In traffic accidents a forceful impact on the front of chin may also cause an annular fracture probably...
4
Comminuted fracture
Pond fracture
Sutural fracture
Ring fracture
Anatomy
Special topics
a5b7534c-742e-4c62-9ad6-d83c0e215054
multi
Minimum Alveolar concentration of halothane is
Halothane is a potent anesthetic with a MAC of 0.74%. Its blood/gas partition coefficient of 2.4 makes it an agent with moderate induction and recovery time. It is not a good analgesic and its muscle relaxation effect is moderate.
1
0.74%
1-2%
6%
2%
Anaesthesia
null
b54da3ac-d32d-43c3-8221-6e3b8cb5142d
single
HPV is associated with ?
Ans. is 'd' i.e., Carcinoma head neck Cancers associated with HPV are :?Cervical carcinomaAnal carcinomaVulvar carcinomaPenile carcinomaVaginal carcinomaOropharyngeal carcinoma (soft palate, base of tongue, tonsils).
4
Carcinoma lung
Carcinoma brain
Carcinoma kidney
Carcinoma head neck
Microbiology
null
708e5fd6-3ef0-48cd-a8e5-2f853102204b
single
Contraindication of induction of labour :
Hea disease
4
PIH
Bad obstetrical history
Diabetes
Hea disease
Gynaecology & Obstetrics
null
4ce0b68f-5e1b-42a0-b1bd-fa06c1e064e6
single
Which technique is used to study structure of molecules -
In the question, they have not mentioned about the nature of structure such as 1o, 2o or 3o etc. In this case, consider teiary structure (3D structure). So, mark X-ray crystallography (X-ray crystallography can detect 3-D structure of any macromolecule). ADDITIONAL INFORMATION ON THIS TOPIC Mass spectrometry: Best tech...
1
X-ray crystallography
Ion exchange chromatography
Electron microscopy
Agarose gel electrophoresis
Biochemistry
Proteins bonds and structure
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multi
Which of the following bacterium is non-motile? (D. REPEAT 2013)
Ref: Colour Atlas and Textbook of Medical Microbiology. Elmer W Koneman, 5th edition, Page 195Explanation:Please note that all the bacteria asked in the options are members of the Enterobacteriaceae.Here is a list of enterobacteriaceae members with their motilitv.Motile Enterobacteriaceae aceae membersNon-motile Entero...
1
Klebsiella spp.
Citrobacter spp.
Escherichia spp.
Salmonella spp.
Microbiology
Enterobecteriaceae
708ab9db-f8ac-4248-96e9-7d46fcca95f8
single
Gravindrex test can detect pregnancy in: MAHE 12
Ans. 2 weeks
1
2 weeks
4 weeks
8 weeks
12 weeks
Forensic Medicine
null
413c5fab-5c87-4a54-9b5e-3f0a460b1554
single
The immediate treatment of 10 kg weight infants presented with tetany -
Ans. is 'b' i.e., IV calcium gluconate with cardiac monitory
2
IV Diazepam
IV calcium gluconate with cardiac monitoring
IV slow phenobarbitone
Wait and watch
Pediatrics
null
abdf0e47-7ea3-41d7-b435-5dd8b3c69047
single
Carphologia is seen in:
Carphologia is seen in Datura poisoning Typical pill rolling movements Pull imaginary threads from fingeips Threads imaginary needles Other sign and symptoms: Dry mouth, irrelevant slurred speech, dry and hot skin, dilated pupils. Physostigmine, a reversible acetylcholine-esterase antagonist, is effective treatment for...
1
Datura poisoning
Digitalis poisoning
LSD overdose
Alcohol withdrawal
Forensic Medicine
Toxicology - 1
2fb68cbd-7016-448e-a3dc-96a68ae90acc
single
A lady wants LASIK surgery for her daughter. All the following are indications for performing LASIK surgery, EXCEPT:
Currently FDA has approved the use of LASIK only in people above 18 years of age. Indications for performing LASIK includes myopia, myopic astigmatism and hyperopia. Hyperopia ranging upto 6 diopters is correctible but at a higher level of attempted correction, predictability is reduced. Ref: Lasik: Fundamentals, Surgi...
1
Age of 15 years
Myopia of 4 Diopters
Stable refraction for 1 year
Corneal thickness of 600 microns
Ophthalmology
null
cb393cb3-b202-4426-ba05-1e68b5d046ed
multi
Test shown in the video is for which structure & its nerve supply:
Test shown in the video is for Supraspinatus (C5,C6) Empty can test: This tests the strength of Supraspinatus . The patient is asked to raise his /her arms to a position of 90-degree abduction,30 degrees of forward flexion and internal rotation(thumbs pointing to the floor, as if emptying an imaginary can) The examiner...
3
Infraspinatus C6,C7
Subscapularis C5,C6
Supraspinatus C5,C6
Teres minor C6,C7
Orthopaedics
Nerve Injuries - 1
a5534a3b-8d71-4c8b-90fb-e14a574464dc
single
Most common complication of meningitis in children is -
Ans. is 'b' i.e., Seizure Complications of meningitis in children Seizure is the commonest complication of meningitis in children. It occurs in about 30% of patients. o Other common complications of meningitis. 1) Subdural empyema or effusions -- It is commonly seen after meningitis with H. Influenza. 2) Brain Abscesse...
2
Hearing loss
Seizures
Hydrocephalus
Mitral regurgitation
Pediatrics
null
3bcd606b-9813-4466-8263-3d4bfa144f1a
single
Watery diarrhea in children is caused by ?
Ans. is 'b' i.e., EPEC
2
ETEC
EPEC
EEC
EAEC
Microbiology
null
4f2f152d-0875-48a0-a15c-0072a60fbf09
single
Which of the following is not included in &;5 cleans&; in conduct of delivery?
Cleans of safe Delivery: &;Five cleans&; (Practices) under strategies for elimination of neonatal tetanus include, Clean delivery surface Clean hands (of bih attendants) Clean cord cut (blade or instrument) Clean cord tie Clean cord stump (no applicant) Ref: National Health Programs of India by Dr. J. Kishore 8th editi...
2
Clean hands
Clean perineum
Clean cutting and care of cord
Clean surface for delivery
Social & Preventive Medicine
Maternal and child care
d1e0f2d1-0396-4f1a-9d0d-9522916eb9ce
single
High false positive cases in a community signify that disease has:
High Incidence and Low Prevalence Actually when a disease has high incidence and low prevalence, it implies people are getting cured earlier. Low prevalence leads to high false positives as chances of picking a healthy person wrongly is higher. If there is higher incidence but low prevalence, then by the time the confi...
2
High prevalence and Low incidence
High incidence and Low prevalence
Low prevalence and Low incidence
High incidence and High prevalence
Social & Preventive Medicine
Definition and Concepts, Examples from NHPs
40cc497f-8dac-4eb2-8ffe-6a2d84daa99f
multi