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A patient with ear discharge presents with diplopia and fever. What is the most probable diagnosis?
Presence of fever and diplopia in a patient with ear discharge suggests lateral sinus thrombosis, an intracranial complication of chronic suppurative ottitis media.
3
CSOM
Meningitis
Lateral sinus thrombosis
Petrositis
ENT
null
79cc612c-7173-443d-864c-38d6a2997c09
single
Dormia basketing is used for removal of renal calculi in the -
null
4
Pelvic ureteric juction
Upper 1/3 of ureter
Middle 1/3 of ureter
Lower 1/3 of ureter
Surgery
null
3204752d-d241-4bcb-b982-5401fdaa6761
single
In a female with appendicitis in pregnancy treatment of choice is
Acute Appendicitis incidence is about 1 in 1000 pregnancies. It is most common nongyneocological cause of acute abdomen requiring surgery. Management of appendicitis Treatment consists of laparotomy at the earliest oppuunity.Once the diagnosis is suspected it is better to operate rather than to wait until generalised p...
1
Surgery at earliest
Aboion with appendectomy
Surgery after delivery
Continue pregnancy with medical Rx
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
763b972e-9c06-4c95-bcb6-7af2e0b91c6f
single
The maximum permissible level of occupational exposure to radiation is ..... Per year -
Park's textbook of preventive and social medicine 23rd edition. * The amount of radiation from outer space and background radiationhas been estimated to be 0.1 rad a year,the additional permissible dose from man made sources should not exceed 5 rad a year.
1
5 rad
2 rad
10 rad
50 rad
Social & Preventive Medicine
Environment and health
99637561-309f-4b51-b325-cadcfec4f986
single
Moribund patient, triage color ?
Ans. is 'b' i.e., Black Triage When the quantity and severity of injuries overwhelm the operative capacity of health facilities, a different approach to medical treatment must be adopted. The usual principle of first come, first treated", is not followed in mass emergencies. Triage consists of rapidly classifying the i...
2
Red
Black
Yellow
Green
Social & Preventive Medicine
null
1af7fc5c-21df-451e-bab9-2cdd76a366d3
single
True about Schatzki&;s ring
SCHATZKI'S RINGS They are semicircular protrusion of lower oesophageal mucosa located at or just above the oesophagogastric junction (squamocolumnar junction). Its under-surface is lined by columnar gastric epithelium. * They involve only the mucosa and submucosa of the oesophagus, not the muscle. * They present with d...
2
Has skeletal muscle
Located at lower esophagus
Causes dysphagia
Contain all layers of oesophagus
Surgery
G.I.T
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multi
Relapsing fever is transmitted by -
Relapsing fever is transmitted by soft tick. Ornithodorus moubata is the soft tick that transmits relapsing fever. These ticks lack scutum. They have 5 nymphal stages. Other diseases transmitted by soft tick are KFD and Q fever. Park's Textbook of Preventive and Social Medicine, 25th Edition, Pg
3
Hard tick
Sandfly
Soft tick
Tsetse fly
Social & Preventive Medicine
Environment and health
fdb55089-60be-409f-8813-22143386b93a
single
One of the following is NOT a sign of diabetic retinopathy-
Non-proliferative diabetic retinopathy (NPDR) Opthalmoscopic features of NPDR include: Microaneurysm are seen in the macular area (the earliest detectable lesion) . These are formed due to focal dilation of capillary wall following loss of pericytes. These appaear as red dots and leak fluid, proteins.", lipids and also...
4
Microaneurysms
Cotton wool spots
Hard exudates
Choroidal neovascularization
Ophthalmology
Vitreous and retina
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single
Maximal level of cardiac output is seen at: September 2009
Ans. C: 30-34 Weeks of Pregnancy The cardiac output stas to increase from 5th week of pregnancy and reaches its peak 40-50% at about 30-34 weeks. Cardiac output increase fuher during labour (+50%) and immediately following delivery (+70%) It returns to pre-pregnancy level by 4 weeks time after labour.
3
22-26 weeks of pregnancy
26-30 weeks of pregnancy
30-34 weeks of pregnancy
34-38 weeks of pregnancy
Gynaecology & Obstetrics
null
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single
A 50 year old woman nulliparous. diabetic and obese presenting with post-menopausal bleeding can be any of the following except :
Carcinoma in situ of cervix
1
Carcinoma in situ of cervix
Carcinoma endometrium
DUB
None of the above
Gynaecology & Obstetrics
null
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multi
Avulsion of extensor tendon give rise to?
It is the flexion deformity of the distal interphalangeal joint usually due to avulsion of extensor tendon of distal phalanx. Ref: Current Diagnosis & Treatment in Ohopedics 3/e, page 538,564-65.
1
Mallet finger
Dupuytren's contracture
Trigger finger
Swan neck deformity
Surgery
null
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multi
Infedelity & jealousy involving spouse is the thought content of which disorder:
B i.e. Othello syndromeIt is characterized by nonbizzare delusion of atleast one month duration with overall well preserved personality (except in the area of delusion) and absence of significant hallucinations.
2
Capgras syndrome
Othello syndrome
Hypochondrial paranomia
Declerambault's syndrome
Psychiatry
null
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True about xenon anaesthesia:
A i.e. Rapid induction and recovery Xenon is ine/ nobel, colourless, odorless, nonirritating, nonflammable and non explosive gas that is heavier than air (4 times), more dense/viscous than N2 & N20, more potent than N20, is very blood insolubleQ (B/G coefficienct 0.14) most ideal inhaled anesthetic agent with very rapi...
1
Rapid induction and recovery
Low potency
High blood solubility
All
Anaesthesia
null
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multi
True about osteoporosis -
Osteoporosis is a metabolic disease.Its characterised by diffuse reduction in bone density.due to decrease in bone mass.It occurs when rate of bone resorption exceeds bone formation. C/f: Loss of bone mass leads to loss of strength so that trivial trauma is sufficient to cause a fracture. A slight loss of height and in...
3
Low calcium
Low phosphate
Cod fish vertebrae
Raised alkaline phosphatase
Orthopaedics
null
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multi
True regarding cardiomyopathy -
Ans. is 'a' i.e., RV dilatation is present; 'b' i.e., May result from thyroxicosis; 'c'i.e. Secondary to alcohol Most common type of intrinsic cardiomyopathy is dilated cardiomyopathy in which all chambers of hea (including right ventricle) are dilated. Thyrotoxicosis and alcohol can cause dilated cardiomyopathy. CMDT ...
4
RV dilatation is present
May result from thyroxicosis
Secondary to alcohol
All
Pathology
null
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multi
Which of the following is a holocrine gland?
INDERBIR SINGH'S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:204 Sebaceous glands The outermost layer are small and rest on a basement membrane.the inner cells are larger,more rounded,and filled with lipid .this lipid is discharged by disintegration of the inner most cells that are replaced by proliferation of outer cells.the ...
4
Sweat gland
Breast
Pancreas
Sebaceous gland
Anatomy
General anatomy
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single
According to WHO the major sign of AIDS children in stage I is the following
According to WHO clinical staging of AIDS in children with confirmed infection, the symptoms of clinical stage 1 are patients may be asymptomatic they have persistent generalised lymphadenopathy. Reference : Ghai essential pediatrics, eighth edition, pg no:226
1
Generalised lymphadenopathy
Not gaining weight
Oral candidiasis
All of the above
Pediatrics
Infectious disease
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multi
Name the structure labelled D
(a) Right common carotid aery(b) Right subclan aery(c) Brachiocephalic trunk(d) Left subclan aery(e) Left common carotid aeryAngiography may be performed using CT, MRI or conventional angiography with a catheter. The catheter can be seen on this image in the aoic arch. Normal variants occur in the great vessels so it i...
4
Right common carotid aery
Right subclan aery
Brachiocephalic trunk
Left subclan aery
Anatomy
Upper limb : Miscellaneous
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single
Methylphenindate is drug of choice for
Ans. b (ADHD). (Ref. Pharmacology by KD Tripathi 5th/- 436; Harrison 18th/27, 369)Drugs used for ADHD# Methylphenidate# Amphetamine# PimolineMethylphenidate acts by releasing NA & dopamine in brain. It is preferred because it causes less tachycardia & growth retardation.
2
Obsessive compulsive disorder
ADHD (attention deficit hypersensitivity disorder)
Enuresis
Autism
Psychiatry
Child Psychiatry
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single
Mechanism of action of quinolones is by?
null
2
Inhibiting DHFRase
Inhibiting DNA gyrase
Inhibiting protein synthesis
Inhibiting cell wall synthesis
Pharmacology
null
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Schedule of post-exposure rabies prophylaxis in HIV infected persons -
Ans. is 'b' i.e., 0,3,7,14,28 o Immunocompromized HIV-infected people might not develop sufficient immunological response, as immunity depends upon the CD4 T-cell-dependent neutrilizing response to the G-protein.o Rabies vaccines are used for post-exposure prophylexis and pre-exposure immunogenicity (pre-exposure proph...
2
0,7, 28
0,3,7,14,28
0, 7, 14, 28
0,3,7,14
Social & Preventive Medicine
Principles of Immunization and Vaccination
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single
Which of the following increases the susceptibility to coronary aery disease:
Von Willebrand's disease, nephrotic syndrome and Familial hyperiglyceridemia (FHTG) also known as type V hyperlipoproteinaemia are not associated with an increased risk of coronary aery diseases. But in SLE the prevalence of coronary aery disease is 10 %. Ref: Harrisons principles of internal medicine, 18th edition, ch...
4
Type V hyperlipoproteinaemia
Von Willebrand's disease
Nephrotic syndrome
Systemic lupus erythematosus
Medicine
null
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single
A pregnant lady presented with 32 weeks of gestation with abdominal pain, elevated BP (160/110 mmHg), with proteinuria and retinal haemorrhage. Next step of management is:
HELLP syndrome is a form of severe preeclampsia. HELLP develops in 10-20% of women with preeclampsia/eclampsia. Signs and symptoms include abdominal pain, commonly occurring in the right upper quadrant or epigastrium, nausea, vomiting, and elevated blood pressure. Proteinuria less commonly accompanies symptoms. HELLP i...
4
Ritodrine
Nifedipine
Magnesium sulphates
Termination of pregnancy
Gynaecology & Obstetrics
null
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multi
REPEAT QUESTION. Renal Calculi associated with proteus infection
Triple phosphate or struvite ( Calcium phosphate with ammonium magnesium phosphate ) is smooth and diy white. It grows in alkaline urine. Proteus being urea splitting organism splits urea to give ammonia and co2 whixh makes urine alkaline and promotes stag horn calculus ref : - Bailey and Love 27th edition ,chapter 76 ...
1
Triple phosphate
Uric Acid
Calcium Oxalate
Cysteine Stones.
Surgery
Urology
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single
In forceful inversion of foot, fracture of the tuberosity of 5th metatarsal is due to pull exerted by which tendon:
Ans. is 'b' i.e. Peroneus brevis Tuberosity or tubercle at the base of 5th metatarsal gives attachment to the peroneus brevis tendon.The base of the fifth metatarsal can be fractured during forced inversion of the foot (pot-hole injury), at which time the tendon of peroneus brevis muscle exerts a pull on the tuberosity...
2
Peroneus longus
Peroneus brevis
Peroneus tertius
Extensor digitorum
Anatomy
Foot
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single
Not true regarding Dandy-Walker cyst:
Characteristic Triad of Dandy Walker : * Hypoplasia of Vermis * Cephalad Rotation of Vermian remnant and Cystic Dilation of Fouh Ventricle extending posteriorly * Enlarged Post Fossa with Torcular Lambdoid inversion
3
Cerebellar vermis hypoplasia
Hydrocephalus
Arachnoid cysts
Posterior fossa cyst
Surgery
Cerebrovascular Diseases
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multi
Tetracycline with highest anti leprotic propey
Minocyline is a tetracycline group given in cases where clozamine is not tolerated minocycline is given in such cases 100mg per day in such cases. Ref: KDT 6/E P753
1
Minocycline
Doxycycline
Demeclocycline
Oxyteacycline
Pharmacology
All India exam
d6e70c2c-bb7f-41fc-aea0-cff55bf0efd0
single
A 50 year old lady with history of jaundice in the past has presented with right upper quadrant abdominal pain. Examination and investigations reveal chronic calculous cholecystitis. The liver functions tests are within normal limits and on ultrasound examination the common bile ducts is not dilated. Which of the follo...
Ans. is 'a' i.e., Laparoscopic cholecystectomy
1
Laparoscopic cholecystectomy
Open choledocholithotomy with CBD exploration
ERCP+- cholecystectomy followed by laparoscopic cholecystectomy
Laparoscopic cholecystectomy followed by ERCP +- choledocholithotomy
Surgery
null
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single
Temporary hardness of water is due to the presence of following salts of calcium and magnesium:
null
1
Bicarbonates
Sulphates
Chlorides
Nitrates
Dental
null
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single
Mechanism of action of terbinafine is?
Antifungal Drugs: CLASS IFICATION 1. Antibiotics A. Polyenes:AmphotericinB (AMB),Nystatin, Hamycin, Natamycin (Pimaricin) B. Heterocyclic benzofuran: Griseofulvin 2. Antimetabolite Flucytosine (5-FC) 3 Azofes A. lmidazoles (topical): Clotrimazole, Econazole, Miconazole, Oxiconazole (systemic): Ketoconazole B. Triazoles...
4
Binds to ergosterol
Prevents formation of purine
Inhition of microtubule formation
Inhibition of ergosterol synthesis
Pharmacology
Chemotherapy
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A 80-year-old patient present with a midline tumor of the lower jaw, involving the alveolar margin. He is edentulous. Treatment of choice:
Surgery is the treatment of choice in mandible cancers. Radiotherapy is contraindicated as it can lead to osteoradionecrosis of mandible. Mandible is managed surgically by marginal or segmental resection. Marginal (rim) resection keeps the outer/lower rim (1 cm thick mandible) intact to maintain cosmesis. It is indicat...
3
Hemimandibulectomy
Commando operation
Segmental mandibulectomy
Marginal mandibulectomy
ENT
null
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single
Race of an individual can be found out by
Cephalic index helps to find the race
3
Ischiopubic index
Corporo Basal index
Cephalic index
Medullary index
Anatomy
All India exam
b1025870-6d69-46bc-9817-e8d5c8803c3e
single
Mechanism of action of propylthiouracilin hypehyroidism is:
(Ref: KDT 6/e p248) Propylthiouracil, carbimazole and methimazole act by inhibiting the enzyme, thyroid peroxidase. It catalyses: Oxidation of iodine Organification Coupling
4
Inhibition of organification of iodine
Inhibition of oxidation of iodine
Inhibition of coupling of two DIT residues
All of the above
Anatomy
Other topics and Adverse effects
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multi
Necrotizing fasciitis is caused by, all except
Ans. is. d. Pneumococcus
4
Staphylococcus aureus
Beta haemolytic streptococci
Clostridium perfringens
Pneumococcus
Microbiology
null
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multi
Tzanck smear test is used in the diagnosis of
Tzanck test is also used for diagnosis of viral diseases like Herpes Zoster.
1
Pemphigus
ANUG
Apthous disease
Lichen planus
Pathology
null
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single
Commonest cause of pulmonary embolism is: CMC (Vellore) 09
Ans. Thrombus
3
Fat
Amniotic fluid
Thrombus
Air
Forensic Medicine
null
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single
Which of the following is observed during sleep induction?
The cholinergic neurons in pontine reticular formation on stimulation, induce sleep. When the activity of norepinephrine and serotonin containing neurons (locus coeruleus and raphe nuclei) is dominant, there is a reduced level of activity in acetylcholine-containing neurons in the pontine reticular formation leading to...
2
| Norepinephrine and serotonin
| Acetyl Choline
| Histamine
| GABA
Physiology
Nervous system
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single
Cherry red spot is seen in all of the following except
.
3
Spranger disease
Faber disease
Retinitis pigmentosa
Central retinal aery thrombosis
Ophthalmology
All India exam
327e5f8e-661c-4a89-b5bc-c8418863256d
multi
BRCA 1 gene is located on chromosome
A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumour suppressor genes. ... Women with harmful mutations in either BRCA1 or BRCA2 have a risk of breast cancer that is about five times the normal risk, and a risk of ovarian cancer that is about ten to thiy times normal.
2
17p21
17q21
13p21
13q21
Pathology
General pathology
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single
A 32-year-old female is admitted to the emergency department with dyspnea, dysphagia, hoarseness, and severe anxiety. Her medical history reveals that she has lived on a liquid diet for some months and has lost more than 30 lb. Over the past several weeks, she has had bloody sputum during attacks of coughing. Fluorosco...
The left recurrent laryngeal nerve passes superiorly in the tracheoesophageal groove after looping around the aorta. The compression of this nerve and compression of the esophagus against the trachea would result in the presenting symptoms. The right recurrent laryngeal nerve loops around the right subclavian artery be...
3
Right recurrent laryngeal nerve
Left vagus nerve, posterior to the hilum of the lung
Left recurrent laryngeal nerve
Greater thoracic splanchnic nerve
Anatomy
Thorax
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multi
Most dietary deficiency of thiamine is the result of poor dietary intake. Thiamine requirement increases in excessive intake of:
Primary food sources for thiamine include yeast, organ meat, pork, legumes, beef, whole grains, and nuts. Milled rice and grains contain little thiamine, if any. Thiamine deficiency is therefore more common in cultures that rely heavily on a rice-based diet. Tea, coffee (regular and decaffeinated), raw fish, and shellf...
1
Carbohydrate
Amino acid
Fat
Lecithine
Biochemistry
null
25a4e4f8-4b44-4084-a1bb-b5ccd1bcb1a3
single
Which of the following infectious disease is treated using multidrug therapy?
Among the options given in the question, multidrug therapy is indicated in the treatment of leprosy. Rifampicin, Dapsone and Clofazimine are drugs used in its treatment. Reference: Essentials of Medical Pharmacology by K D Tripathi, 5e page 713.
2
Syphilis
Leprosy
Typhoid
None of the above
Medicine
null
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multi
Preanesthetic medication is used for A/E :
B i.e. Decrease BP
2
Decrease of anesthetic dose
Decrease BP
Prevent aspiration
Produce amnesia for peri-operative events
Anaesthesia
null
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single
A patient developed breathlessness and chest pain, on second postoperative day after a total hip replacement. Echo-cardiography showed right ventricular dilatation and tricuspid regurgitation. What is the most likely diagnosis-
*Onset of chest pain and breathlessness, together with echocardiographic evidence of right ventricular dilatation and tricispid regurgitation after a high risk procedure like total hip replacement suggests a diagnosis of pulmonary embolism. REF:Campbell's 11th/e Chapter-7
2
Acute MI
Pulmonary embolism
Hypotensive shock
Cardiac tamponate
Anatomy
Miscellaneous
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Treatment of Thyroid crisis are all EXCEPT
C i.e. (Iodine) (714 - CMDT- 09) (2237- H17th) (988 - 09)THYROTOXIC CRISIS OR THYROID STORM* Presents as life threatening exacerbation of hyperthyroidism* Fever, delirium, seizures, coma, vomiting, diarrhea and jaundice* Mortality rate due to cardiac failure, arrhythmia or hyperthermia* Precipitating factors, acute ill...
3
Neomethimazole
Propranol
Iodine
Iodide
Medicine
Endocrinology
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True about Propagated epidemic is following Except
A propagated epidemic is most often infectious origin and results from person to person transmission of an infectious agent.The e[idemic usually shows a gradual rise and tails off over a much longer period of time.The speed of spread depends upon herd immunity, oppounities for contact and secondary atttack rate.Park 23...
1
Secondary waves are absent
Spreads from person to person
The speed of spread depends upon Herd immunity
Shows gradual rise and fall over long period of me
Social & Preventive Medicine
Epidemiology
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Intermediate filaments in muscle cells
Intermediate filaments are used as tumor markers Epithelial cells:keratin Muscle cells:desnin Nucleus:lamin Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:8,9,14
1
Desnin
Keratin
Vimentin
Lamin
Anatomy
General anatomy
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single
Elevated levels of alkaline phosphatase are typical findings in each of the following conditions EXCEPT-
ALKALINE PHOSPHATASE. Serum alkaline phosphatase is produced by many tissues, especially bone, liver, intestine and placenta and is excreted in the bile.
4
Cirrhosis
Hepatitis
Polycythemia vera
Myocardial infarction
Pathology
miscellaneous
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multi
Central macular fixation develops at
The critical period of developed of fixation reflex is 5-6 months of age.This is the reason why unilateral cataracts in children should be operated early.Remember - Binocular vision develops at 5-6 years.
4
3 weeks
6 weeks
3 months
6 months
Microbiology
All India exam
0de79a99-7a64-44fc-98cc-ca69436cbddc
single
In gene cloning, largest fragment can be incorporated in -
null
3
Plasmid
Bacteriophage
Cosmid
Retrovirus
Biochemistry
null
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single
Action of topoisomerase III ?
Ans. is 'd' i.e., Single strand breakTopoisomerase I Removes negative supercoiling.Topoisomerase II Relaxes positive supercoils and forms negative supercoiling by condensation. of chromosome.Topoisomerase III Can introduce single strand breaks during recombination that are required for DNA to be exchanged by adjacent c...
4
Remove positive supercoil
Remove negative supercoil
Form negative supercoid
Single strand break
Biochemistry
null
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single
Hemiplegia is most commonly due to Occlusion Of?
The MCA is the most common site for the occurrence of ischemic stroke. Contralateral hemiparesis and hemisensory loss of the face, upper and lower extremities is the most common presentation of MCA syndrome Ref Harrison20th edition pg 2234
1
Middle cerebral aery
Basilar aery
Veebral aery
Anterior cerebral aery
Medicine
C.N.S
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single
The use of porcelain laminates is indicated for:
All other options are relative contraindications of porcelain veneers.
3
Teeth in parafunction
Heavily restored teeth
Closure of 1 mm diastema
Lower anterior teeth
Dental
null
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single
All of the following are features of acute nongranulomatous iridocyclitis except:
Ans. Minimal aqueous flare
3
Marked ciliary congestion
Numerous small keratic precipitates
Minimal aqueous flare
No iris nodules
Ophthalmology
null
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multi
Neonatal sepsis and meningitis most common cause –
null
2
Streptococcus pyogenes
Streptococcus agalactacea
Enterococcus fecalis
Staphylococcus aureus
Pediatrics
null
50285059-78da-4a3b-bf32-28e4bdc80abb
single
T/t used for lower ureteric stone is
Ans is 'a' ie Endoscopic removal Best modality of t/t for ureteric stone is - Ureteroscopic removal.There are other methods alsoEndoscopic Dormia basket - can only be used for small stones that are within 5-6 cm of the orifice.This has been replaced by ureteroscopic technique.Endoscopic Meatotomy - this is for removal ...
1
Endoscopic removal
Diuretics
Drug dissolution
Laser
Surgery
Urolithiasis
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single
A multipara patient was brought to the emergency with signs and symptoms of small bowel obstruction. After resuscitation, X-ray was performed and the findings are given below. What is the most probable diagnosis?
X-ray: kidney- Bean sign | Cecal volvulus Cecal volvulus: Misnomer Ileoceco-colic volvulus Small bowel obstruction S/S Predisposing factors: Multiparity Ligament dividing Sx - for mobile cecum Malrotation Distal obstructing lesion X-ray findings Kidney bean sign Comma shaped cecum Mx: Ileocolectomy + Ileotransverse ana...
4
Adhesive small bowel obstruction
Crohn's disease
Obstructed hernia
Cecal volvulus
Surgery
Large intestine
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multi
Drug of choice for treatment of chloroque resistant falciparum malaria-
Ans. is None o Aemisinin base combinations are DOC for chloroquine resistant falciparum malaria. o If you will have to choose one option, go ahead with option 'a' i.e. quinine, as quinine can be used along with doxycycline if aemisinin based preparations are not available. Remembers very simple funda o Forget about chl...
4
Quinine
Chloroquine
Pyrimethamine
null
Pharmacology
null
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Incision for superficial parotidectomy:-
Incision for superficial parotidectomy is S-shaped. Parotidectomy: The most commonly used incision is the 'lazy S' pre-auricular-mastoid-cervical. Name of incisions for parotidectomy: Lazy 'S', modified Blairs or Sistrunk incision
3
L-shaped
Y-shaped
S-shaped
Z- shaped
Surgery
Salivary Glands
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During ventricular pressure pulses square root wave is seen in -
null
4
ASD
MVPS
Dilated cardiomyopathy
Constrictive pericarditis
Medicine
null
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single
All are reduced in Iron deficiency anaemia EXCEPT:
Ref: Robbins E- Book P 454Iron deficiency anaemia has all parameters reduced except Total iron binding capacity. Iron deficiency anemiaHematocrit| to |||MCV| to |||MCHC|Serum iron| to |||Serum TIBCNormal to | Serum ferritin| to ||Stainable iron in marrowAbsentReticulocytesNormal to |
1
T.I.B.C
Percentage saturation of Transferrin
Hemoglobin
Ferritin
Pathology
Hemodynamics
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Lyme disease is caused by:
Ans. (b) Borrelia BurgdorferiRef.: Microbiology by Ananthanarayan and Paniker 8th ed. /377, 379, 381* Causal agent of lyme disease: Borrelia Burgdorferi (I.P. 3 to 30 days)# Vector: Ticks* Lyme disease occurs in 3 stages:# Stage 1: localized infection, appears an annular skin lesion (Erythema Migrans)# Stage 2: dissemi...
2
Borrelia vincenti
Borrelia Burgdorferi
Borrelia Recurrentis
Treponema Pertenue
Microbiology
Mycology
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single
Which is the most common cranial nerve involved in raised ICP?
A-Abducens= Longest subarachnoid course(so whenever ICP will raise abducens nerve will affect first) B-Trochlear=Longest intracranial route, thinnest, only nerve has dorsal origin C- Trigeminal=Thickest nerve D-Facial= Longest intraosseous route
1
Abducens
Trochlear
Trigeminal
Facial
Medicine
Raised ICP and Brain death
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single
By estrogen administration in a menopausal woman, which of the following is increased?
Hormone therapy reduces the rate of bone resorption and results in an increase in bone mass density (BMD). Estrogen therapy acts the inhibition of bone resorption. Both BMD and fracture rate are improved with estrogen therapy. However, with cessation of estrogen therapy, there is a rapid and progressive loss of bone mi...
3
Gonadotrophin secretion
LDL-cholesterol
Bone mass
Muscle mass
Gynaecology & Obstetrics
null
b8d419e6-4bcb-40ac-b4b5-94f38a8b59c2
single
Which one of the following is found on the crown of permanent mandibular first molars but is not found on the crowns of mandibular second molars?
DB developmental groove is not found on mandibular second molars.
2
MB cusp.
Distobuccal groove.
Lingual groove.
DB cusp.
Dental
null
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Which of the following is the diagnosis for a condition having mutation in COL4A5 chain?
COL4A5 chain represents the a5 chain of collagen type IV. It is associated with the development of Alpo Syndrome.
1
Alpo's syndrome
Good pasture's syndrome
Thin membrane disease
Nodular glomerulosclerosis
Pathology
Basic Concepts
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single
A patient presented with hemoptysis and persistent cough. The chest X-ray of the patient was normal. The next best investigation is?
* For most patients, the first step in evaluation of hemoptysis should be a standard chest radiograph. * If lesion is not seen then a high resolution CT chest should be done for visualization of lesion . * If all of these studies are unrevealing, bronchoscopy should be done .
2
Helical CT
High resolution CT
Bronchoscopy
Angiography
Medicine
Miscellaneous Questions
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Autosplenectomy occurs in:
b. Sickle cell anemia(Ref: Nelson's 20/e p 2336, Ghai 8/e p 345)Patients of sickle cell anemia may undergo auto-splenectomyQ due to multiple infarcts in splenic artery, that causes spleen to be reduced to fibrous tissue (splenic atrophy spleen may become non-palpable).
2
Thalassemia
Sickle cell anemia
HbH disease
Hydrops fetalis
Pediatrics
C.V.S.
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single
Third generation IUCD ?
Ans. is 'a' i.e., Mirena
1
Mirena
Nova-T
Lippe's loop
CuT-200
Social & Preventive Medicine
null
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single
Saturnism is a feature of?
Ans. (b) Lead poisoningRef. Parikh 6/e, p 9.18
2
Mercury poisoning
Lead poisoning
Arsenic poisoning
Thallium poisoning
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
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multi
Which of the following is known as suicidal enzyme? (AIIMS November 2013, May 2013)
Ans. b. Cyclooxygenase (Ref: Harper 27/e p204 Harrison 18/e p146Cyclooxygenase is a suicidal enzyme.Suicidal enzyme is one. which undergoes self-destruction in order to terminate its own acitivity. e.g. Cyclooxygenase.Switching off of prostaglandin activity is partly achieved by a remarkable property of cyclooxygenaseQ...
2
Lipoxygenase
Cyclooxygenase
Thromboxane synthatase
5' nucleotidase
Biochemistry
Mechanisms of Enzyme Action
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Compound microscope was invented by: September 2004
Ans. C i.e. Robe Hook
3
Louis Pasteur
Hippocrates
Robe Hooke
Leeuwenhoek
Microbiology
null
335056bb-f185-4686-87b0-19c3d2dd7f60
single
Pancreatic juice rich in water and electrolytes poor in enzymes is secreted in response to :
C i.e. Secretin
3
Pancreatozymin
Cholecystokinin
Secretin
Proteins
Physiology
null
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single
Metabolism of drugs is mostly done by which enzyme-
Ans. is 'b' i.e., Cytochrome P450 o Biotransformation reactions (metabolism) of drugs can be classified :A. Non-synthetic (phase I) reactions# Metabolism brings about a change in the drug molecule by:1. Oxidation2. Reduction3. Hydrolysis4. Cyclization5. Decyclization# The new metabolite may retain biological activity o...
2
Cytochrome C
Cytochrome P450
Glucronyl transferase
Acetylase
Pharmacology
Pharmacokinetics
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single
Hard chancre is seen in?
Ans. b (Syphilis). (Ref. Harrison, Internal Medicine, 15th ed., 845, 990, 1045, 1191 and 1220).Chancres are seen in chancroid, syphilis, tularemia, African trypanosomiasis and few other parasitic diseases. SyphilisChanchroid1PapulePustule2Usually singleUsually multiple, coalesce35-15 mm diameterDiameter variable4Sharp ...
2
Chancroid
Syphilis
Tularemia
All
Skin
S.T.D.
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STEPS is for -
Ans. is 'b' i.e., Non-communicable disease STEPS risk factorso The WHO STEPwise approach to surveillance of non-communicable diseases risk factors (STEPS) was developed by WHO as a part of a global surveillance strategy in response to the growing need for country-level trends in non-communicable diseases.o By using sam...
2
Communicable disease
Non-communicabie disease
Both
null
Social & Preventive Medicine
Non-Communicable Diseases
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multi
Cause of myringosclerosis ?
Ans. is 'b' i.e., Grommet inseion Tvmpanosclerosis Tympanosclerosis is a condition in which there is calcification of tissue in the eardrum (tympanic membrane) and middle ear. Tympanosclerosis may be classified as : - Myringosclerosis : - Involving only the tympanic membrane. Intratympanic tympanosclerosis : - Involvin...
2
Genetic
Grommet inseion
Otosclerosis
null
ENT
null
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multi
Site of lesion affecting V, VI & VII cranial nerve
B. i.e. Pons- 3rd & 4thQ cranial nerve attach to mid brain; 5th Q c.n. to pons; 6t1, 71), & gth Q to junction between pons & medulla; 9th, 10th, 11th, & 12th Q attach to medullaAcoustic neuroma is most common cerebellopontine angle tumorQ. 5th nerve is the earliest nerve to be involved.Q f/b gth, 9th, 10th, 6th, 7th et...
2
Midbrain
Pons
Medulla
All
Anatomy
null
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multi
Which is inhibitor to cytochrome oxidase?
Ans. is 'd' i.e., Cyanide Inhibitors of Electron transport chain (Respiratory chain)o Complex I:- Barbiturates (amobarbital), piercidin A, rotenone, chlorpromazine, guanithidine.o Complex II:- Carboxim TTFA, malonate.o Complex III :- Dimercapro!, BAL. actinomycinA, Naphthyloquinone.o Complex IV(cytochrome c oxidase) Ca...
4
Malonate
BAL
Oligomycin
Cyanide
Biochemistry
Respiratory Chain
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single
Patient is treated with dentrolene. All the following are adverse effects except:
- Central muscle relaxant - Used in malignant hypehermia, neuroleptic malignant syndrome etc- Cause respiratory muscle weakness - breathlessness- Chronic dantrolene use - liver dysfunction, kidney dysfunction- Bradycardia Dantrolene contributes to prolonged non depolarizing neuromuscular blockade, In addition to volati...
1
Hypokalemia
Muscle weakness
Breathlessness
Bradycardia
Anaesthesia
JIPMER 2017
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multi
The following is of serious pathological significance in infants –
An infant should gain weight progressively, except for the first few days of life. Liver, spleen and kidney may be palpable in normal newborn. ___________________ Nelson Sometimes trachea may be deviated from midline without any significance.
1
Loss of weight
Palpable left kidney
Palpable spleen
Deviation of trachea from midline
Pediatrics
null
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single
An oval radiolucent area between the apices of maxillary incisors is
null
1
Nasopalatine foramen
Lingual foramen
Nasal fossa
Incisive canal
Radiology
null
ec8bb7ac-e653-47e8-b76e-7c167559c7f8
single
In a patient with starvation for 72 hrs which of the following would be seen:
D i.e. Increased GluconeogenesisEnergy is derived mainly from glycogenolysis (initial few hours) -gluconeogenesis (upto 72 hours) -*Degradation of fast (3 days - 2weeks) -*Break down of tissue protein (last 1 weeks)Q
4
Increased glycogenolysis
Increased ketosis due to break down of fats
Degradation of proteins
Increased gluconeogenesis
Biochemistry
null
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single
The leukotriene receptor antagonist used in bronchial asthma is -
Ans. is 'a' i.e., Zafirleukast
1
Zafirleukast
Zileuton
Ketotifen
Nedocromil
Pharmacology
null
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single
Hepatitis B infectivity is indicated by:
Answer is B (HBs Ag + HBe Ag) HBe Ag: Its principal clinical usefulness is an indicator of relative infectivity - Harrison HBs Ag: Its presence in serum indicates infection /pervious vaccination with hepatitis B virus. HBs Ag Anti- HBsAg Anti Hbe HBe Ag Anti-Hbe Acute HBV infection High infectivit - IgM + - Chronic HBV...
2
Anti-HBsAg
HBsAg + HBeAg
Anti-HBsAg - Anti-HBc
Anti-HBeAg + Anti-Hbs Ag
Medicine
null
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single
'Amount of liquor is maximum at :
36-38 weeks
2
32-34 weeks
36-38 weeks
34-36 weeks
38-40 weeks
Gynaecology & Obstetrics
null
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single
All of the following statements hold true for melanoma of vulva except :
Melanoma of vulva accounts for 3-5% of all vulval tumors It may arise de novo,but some arise from a pre-existing juctional naevus. occur frequently on clitoris or labia minora have poor prognosis Reference : textbook of gynaecology Sheila balakrishnan, 2nd edition, pg no: 292,293
2
It is the 2nd most common vulval cancer
M/C site is labia majora
May arise from junctional nevus
Has a poor prognosis
Gynaecology & Obstetrics
Gynaecological oncology
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multi
Tzank smear is done for all except
Tzanck smear is a bedside test. It enables cytodiagnosis in vesicular and bullous lesions to demonstrate acantholytic or multinucleated cells. Acantholytic cells are keratinocytes which are large round cells with a dark central nucleus and peripheral condensed pink cytoplasm. These cells may be singular or in groups an...
4
Varicella
Herpes
Pemphigus
Psoriasis
Dental
Vestibulobullous disorders
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multi
Absorption of which of the following drug increases with food intake ?
null
3
Tetracycline
Diazepam
Griseofulvin
Ampicilin
Pharmacology
null
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single
After taking a drug a patient developed some abdominal problem for which he consulted a physician, who adviced X-ray. X ray findings was radiopacity in bowel. Probably he might have taken A/E:
D i.e. Coicosteroid
4
Salicylate
Iron
Phenothiazine
Coicosteroid
Radiology
null
3ec7904c-a266-41f6-b504-ce8ebe906a4f
single
Which of the following produces VWF:
Ans. (A) Endothelial cells(Ref: Robbins and Cotran Pathologic Basis of Disease 10th ed; Pg 489)Synthesis of VWF is large multimeric glycoprotein in blood plasma and produced constitutively as ultra-large VWF in endothelium (in the Weibel-Palade bodies), megakaryocytes and platelets (a-granules of platelet), and subendo...
1
Endothelial cells
Platelets
Neutrophils
Macrophages
Pathology
Blood
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Epithelial lining of Baholins duct is :
Transitional Epithelium
2
Columnar
Transitional
Cuboidal
Squamous
Gynaecology & Obstetrics
null
1887db8b-78e2-4895-be9e-a1edd592ddff
single
What is the term used for microbial killing by an antibiotic below its "Minimum inhibitory concentration"?
Post antibiotic effect refers to continued suppression of bacterial growth that persists after removal of an antimicrobial agent. When a drug has prolonged post antibiotic effect it may be effective against pathogens even during intervals between the doses when serum and tissue levels have dropped below MIC. Carbapenem...
4
Concentration dependent killing
Time dependent killing
Sequential blockade
Post antibiotic effect
Pharmacology
null
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single
Female presents to gynaecological OPD with a complaint of cyclical pain, dyspareunia and infertility. The best investigation to establish the diagnosis would be-
Clinical features of infertility, dyspareunia, and cyclical pain (i.e. dysmenorrhea) are highly suggestive of endometriosis and the investigation of choice/ gold standard investigation for the diagnosis of endometriosis is laparoscopy. TVS is the mainstay for evaluating symptoms associated with endometriosis. It is acc...
2
TVS
Diagnostic laparoscopy
Hormonal study
Aspirate from the pouch of douglas
Gynaecology & Obstetrics
null
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single
WHICH OF THE FOLLOWING IS NOT A PA OF NEPHRON ?
Nephron - Nephron is the structural and functional unit of kidney and there are about 1-4 million nephrons in each kidney. The nephron consists of a renal corpuscle (or Malpighian corpuscle), and a long complicated renal tubule. Renal tubule is made up of three pas: The proximal convoluted tubule, Loop of Henle, The di...
2
The distal convoluted tubule
Loop of Henle
The proximal convoluted tubule
Collecting Duct
Anatomy
General anatomy
c261eea2-53da-4ea4-b4ad-1226971a421c
single
Bird shot retinopathy is characterised by all except
Birdshot chorioretinopathy, also known as birdshot uveitis, birdshot retinopathy, or HLA-A29 uveitis, is an uncommon chronic posterior uveitis characterized by vitritis and multiple ovoid spots, which are orange to cream in color and hypopigmented Ref AK khurana 6/e p 280
2
Common in females
Unilateral
HLA 29 positive
Creamy yellow spots
Ophthalmology
Vitreous and retina
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While analyzing a data, allocation into similar groups is done to ensure -
Both groups (study and control) should be comparable in respect of all the possible varibles, which may influence the outcome. So that, except for the factor under study will not influence the outcome → confoundation and bias can be minimized.
1
Comparability
Accuracy
Validity
Sensitivity
Social & Preventive Medicine
null
26fb9e2e-d422-4137-acde-e2625c9dc05b
multi
Vestibular Schwannoma arises most frequently from:
Superior Vestibular nerve is the most common nerve of origin, followed by Inferior Vestibular Nerve.
1
Superior Vestibular Nerve
Inferior Vestibular Nerve
Cochlear Nerve
Facial Nerve
ENT
null
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single
Sickle cell trait patient do not have manifestations as that of Sickle cell disease, because:
In Sickle cell trait, the patient is heterozygous and only one parent contributes the abnormal S gene. in each cell of these patients approximately 40% of the hemoglobin is HbS. The rate of sickling is influenced by the intracellular concentration of hemoglobin S and by the presence of other hemoglobins within the cell...
1
50% HbS is required for occurrence of sickling
HbA prevents sickling
50% sickles
HbA prevent polymerization of Hbs
Pathology
null
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single
A 1–month old baby present with frequent vomiting and failure to thrive. There are features of moderate dehydration. Blood sodium in 122 mEq/1 and potassium is 6.1 mEq/1. The most likely diagnosis is –
Blood parameters indicate Hyponatremia and Hyperkalemia in this patient. All conditions other than 21 hydroxylase deficiency present with Hypokalemia.
3
Gitelman syndrome
Bartter syndrome
21–hydroxylase deficiency
11–β hydroxylase deficiency
Pediatrics
null
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single