Datasets:
habdine
/
Prot2Text-Data

Dataset card Data Studio Files
xet
Community
1
accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
16
2.75k
function
stringlengths
6
5.51k
AlphaFoldDB
stringlengths
6
10
B5EB44
COAD_CITBB
Pantetheine-phosphate adenylyltransferase
Citrifermentans
MPLKLAVYPGSFDPVTYGHLDIIDRGLKIFDGVIVAVARNSEKNALFTVQERIELLTEILKDRPEARVETFDGLLVDYVRRVGASVVIRGLRAVSDFEFEFQLAQMNRNITRDVETLFMMTSVPYSYLSSSIVKEVSCLNGPVDKLVPPLVKSALDAKFRG
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
B5EB44
Q47EL1
ISPF_DECAR
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Dechloromonas
MNFRVGQGYDVHKLVDGRKLILGGVEIPHPTGLLGHSDADALLHAITDALLGAVALGDIGRHFPDTDPRYKGADSRVLLRAAVALLAERGWRPVNVDATLIAQQPKLAPHAVAMVANVAADLGISPDCVNIKGKTNERLGYLGREEAIEAQAVALVERVG
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Q47EL1
Q2S6X5
NAGB_HAHCH
Glucosamine-6-phosphate isomerase
Hahella
MRVIIADSPEAVARMGAEQCIRLLQDKPAAVLGLATGSTPIALYAHLIQRRQQGEVSFHQVRTFNLDEYIGIAPQHPQSYRSFMQKQLFDHIDVLPENTHIPNGMGDPIAESRAYEDKIHSAGGIDLQILGLGRNGHIGFNEPTSSLSSRTRAKTLTQETIRDNSRFFSADEEQPHLAITMGIGTILDARKIMLLAAGAAKADAVKAMVEGPISAMHPASALQMHPSALVIVDTDAASKLELIDYYRWVQSETLRVQGAYL
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
Q2S6X5
A0A2H5RJD4
CRN1_RHIID
Crinkler effector protein 1
Rhizophagus
MSITLLCLIKGNTLANAFPVDIDKDQLVGHLKKVIKAEQPQTFANVDAKDLKLWRVPISDDHDDQLRNLSLEDSDELLAIRKISKYFPDSPPEECIHVLVEPPESTATSEVLKLREEVASLQALLNKSVAFDVVVSPKRTKGFKWTVNIEQATLDGLKEHIRKMEKPPALENDGAVLNIVNESGKYSPLNDQDLREMLQLFVSNKNLKFTVFIETPSKAFSDWTFSSVCQLYGLNGETEDPTMTVFPNFSCGNVKPSQESLEGLMAELKSRLDNTPISLLSVEATKSLYVYSYLLAGANNFKGKFEIRPQKVISGPNGHGPLDFAIDLCQTAKTVGVTEVKKDDFVKGVAQCAVQLESSLSYRKRKADEMEERTFGRVFGIVTDAEKFYFMECSMDDQDRPSFKLSKPVTVVYEDNDLQTKVEKVLEHIVWLLEEAQKPDSALDVKEREIKRVRSGELPKVTDLEGKTN
Effector that participates in the arbuscule development step of the symbiosis. Arbuscular mycorrhizal (AM) symbiosis is one of the most prominent and beneficial plant-microbe interactions that facilitates mineral nutrition and confers tolerance to biotic and abiotic stresses . Is not involved in cell death processes .
A0A2H5RJD4
O79881
NU4M_PIG
NADH dehydrogenase subunit 4
Sus
MLKIIIPTTMLLPMTWMSKHNMIWINATVHSLLISLISLSLLNQLGENSLNFSLTFFSDSLSAPLLVLTTWLLPLMLMASQSHLSKETTTRKKLYITMLILLQLFLIMTFTATELILFYILFEATLVPTLIIITRWGNQTERLNAGLYFLFYTLAGSLPLLVALVYIQNTTGSLNFLIIHYWSHPLSNSWSNIFMWLACIMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRITTILNPLTNYMAYPFLMLSMWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAIMIQTPWSFMGATALMIAHGLTSSMLFCLANTNYERVHSRTMILARGLQTLLPLMATWWLMASLTNLALPPSINLIGELFIITASFSWSNITIILMGMNMMITALYSLYMLITTQRGKYTHHINNIKASFTRENALMALHILPLLLLTLNPKMILGPLY
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
O79881
Q8KQN8
CPHE_PSEAG
Extracellular cyanophycinase
Pseudomonas
MIRSFIRSSALLLALLPVTGYSAGPLILVGGGLKDDNTAIYQRLIQLAGGNGQARIGVITAASIPESDDPDAGTADAANSKANGEFYAQLLETYGAADAQWIPIDLDQISNNSNPQVVAQINSMTGFFFGGGDQSRLTQTLQTATRADSPALAAIRARHNAGAVLAGTSAGTAIMVQGPMVTGGESYDGLRYGVYTTPSGDDLSYDMQGGFGFFNYGLLDTHFSERGRQGRIVRLADHTQVPFAFGVDENTALLVQNNATLGQVEMEVIGENGVFIFDLRNKERGTGSTYALYDVLGSYLTAGDRYRPVTGQFVIASGKTSLRGRERYSAAMTVTTDIFSSPNNSGANGRRKPREFVKVSADLFDSRVTSTLGRTYETNPLSRRSVQKHAVRQPWLPGHRWRQEHAVLPAFADGFPS
Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.
Q8KQN8
Q8EEW2
NAGZ_SHEON
N-acetyl-beta-glucosaminidase
Shewanella
MSYLMLDLLSLDVSEAEAEMLRHPQVGGLILFSRNFTSREQLIALVQQIRQIRPEILIAVDHEGGRVQRFREGFTLIPAMGDILPAAKGDMALAKRWACELGFLMAIELLACDIDLSFAPVLDLNGISQVIGKRSFSANPDEVIALARSFIEGMAQAGMGAVGKHFPGHGSVAADSHIAQPIDEREGEVIFNQDILPFKELIFNGKLSGIMPAHVIYPKVDPNPAGFSSYWLKQILRKELGFNGVIFSDDLGMKGASFAGDYVGRAKAALDAGCDMILVCNDNPGVMTLLNGFVWPEAAPQHPASLLKPNMAQTALALENSARWENAKQLAEQIQLAQQAKV
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
Q8EEW2
Q8UD04
ALLA_AGRFC
Ureidoglycolatase
Agrobacterium tumefaciens complex
MTDFLEIRPLTKEAFTPFGDVIETTPSSMRHINGGQTERHHALSAPEAAGEGARIILNIFRGQPRVFPHKIDMMERHPLGSQSFSPLSGRPFLVVVAQDDGGRPARPQVFLARGDQGVNYRRNVWHYPLMPLQAVSDFLVADREGPGNNLEEYFFDEPFMIAEPSL
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
Q8UD04
Q7NMQ7
RSMG_GLOVI
16S rRNA 7-methylguanosine methyltransferase
Gloeobacter
MDSGALWQDLGWQPDTLQARSFERLYALVLAGNTRLNLTRITGREEFWEKHLFDSLRGLAAFQDQKEPSLIDIGTGAGFPGLPIAIAHPDWYVVLVDSVRKKIAFVLSTIQALGLTNAQALTGRAEDLAHRREHRESYDLAVLRAVAQANVCAEYALPFVKLGGAAVLYRGNWEVQEEVELARACRALGGEIVEVDAFELPVSRAVRHCVVIRKTGPGLRVFPRPAGLPTQHPLGAIEGAPRVESEEPEEP
Specifically methylates the N7 position of a guanine in 16S rRNA.
Q7NMQ7
Q8Q0J1
OTC_METMA
Ornithine carbamoyltransferase
Methanosarcina
MKRDVLSITDLSREEIYELLESAADLKKKRKAGEPTEYLKHKSLGMIFEKSSTRTRVSFEVAMSDFGGHALYLNSRDIQVGRGETIEDTARTLSGYLHGIMARVMSHDTVEKLARFSTIPVINALSDREHPCQILGDFMTIMEYKNRFEGLKFAWIGDGNNVCNSALLGSAIMGMEFVIACPEGYEPGAEFLEKAKALGGKFSITDDPKTAAKDADIIYTDVWVSMGDEAEQEKRLKDFGSFQVNTELLGVAKPDVIVMHCLPARRGLEITDEVMDGPNSVIFEEAENRLHAQKALILKLMR
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
Q8Q0J1
Q1RKD1
NUOH_RICBR
NDH-1 subunit H
belli group
MIELFFEYIFPLIIIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNADKILFVLAPMITFILSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEVSMGLVIITVLLTTGTLNLSQIVEAQRTMPWWIDLMLMPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALFFLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTLFWVVLVSSVLIYTDHLPNV
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
Q1RKD1
Q88FY6
NICT_PSEPK
Nicotinate degradation protein T
Pseudomonas
MPIANATTVHSDIDHGTKALYSKITWRLIPFLCFCYLAAYLDRINVGFAKLQMLEDLQFSTAAYGLGAGLFFVGYIIFEVPSNLILQRVGAKLWIARIMITWGLLSACTMFVTSTTQFYILRFLLGAAEAGFLPGVLYYLTMWYPTYRRGRIIALFMIGLPLSSVIGGPISGWIMGHFDQVQGLHGWQWLFLLEAIPSVLLGILTFWALPNHFQQAKWLSADDKAQLAADLAADDAEGKDSKHSFRDGFFNLKVWMLGGIDFSILLSAYAMGFWMPTFIRDAGVSDTFHIGLLTAIPSLAALAGMLMIGASSDRHRERRWHIIVPFIIGAIAMASSTLFSQNLVMTVVLFAIASAAIIGAVPVFFSLPATFLKGTAAATGFALACSVANIAGLVSNSLMGVVTDLTGTSHAALWVFAGCLILSCFLVIALPAKLVNR
Probable transporter, possibly involved in the aerobic nicotinate degradation pathway.
Q88FY6
Q7VQP7
ORN_BLOFL
Oligoribonuclease
Candidatus Blochmannia
MNEDNLIWIDLEMTGLNPERDRILEIATLITDNELSILSEGPVLTIYQPESQLLLMDEWNTYTHSSNGLLKEVRSSKLNECDASILVLKFLKNWVPCKSSPMCGSSVAQDRRFLLKYMSELESYFSYRYLDVSTIKELMFRWRPDLKTGLQLHKSHRALADIQESVLELKYYRKYFINCN
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
Q7VQP7
B1KQ37
ATPD_SHEWM
F-type ATPase subunit delta
Shewanella
MAEITTIARPYAKAAFDFAIEKNAVDSWAEMLNFAAMVSENETMKPLLSGSLASHQLAELFIGVCGEQVNEQGQNLLKVMAENGRLETLPAVSQLFVEMKHEWAKEIEANVVSATELSSEQQQEISVSLEKRLTRKVKLNCSIDASLIAGLIITAGDLVIDGSVRGKVSRLSDSLQS
This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
B1KQ37
C5BES7
DER_EDWI9
GTP-binding protein EngA
Edwardsiella
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVNGHEFIIIDTGGIDGTENGVETHMAEQSLMAIEEADIVLFLVDARDGLLPADEAIARHLRSRDKATFLVANKTDGIDAEVAVGDFYSLGMGEVHPIAASHGRGVTQLIEDALVPFIPQEAPAPVLSEEEENAAYWAELEAEADGEAQEEEEAFDPINQPIKIAIVGRPNVGKSTLTNRILGEDRVVVYDMPGTTRDSIYIPMERDEREYVLIDTAGVRKRGKVTDTVEKFSVIKTLQAIEDANVVLLVIDARQGISDQDLSLLGFILNSGRSLVVVVNKWDGLSLEVKEQVKDMLDLRLGFVDFARIHFISALHGSGVGNLFESIQEAYESATRRVSTAMLTRIMTMAQDDHQPPMVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRRSLNVMGTPIRIQFKEGDNPFANKRNTLTPNQMRKRKRLLSHLKKTK
GTPase that plays an essential role in the late steps of ribosome biogenesis.
C5BES7
Q09X16
YCF3_MORIN
Photosystem I assembly protein Ycf3
Morus
MSRSRINGNFIDKTFSIVANILLRIIPTTSGEKEAFAYYRDGMSAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTRNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEIAEAWFDQAAEYWKQALALTPGNYIEAQNWLKITGRFE
Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.
Q09X16
P50939
NUOL_RHOCA
NDH-1 subunit L
Rhodobacter
MTTIILLAPLLGALIGGFGWRLITEKGALVVTTGLLFLSCILSWVVFLTLPAETQHIHLLDWIRSGALDTSWGIRLDRLTAIMLIVVTTVSALVHLYSWGYMAHDENWTHHEAYKARFFAYLSFFTFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFYYKKPSANAAAIKAFVVNRVGDFGFALGIMGLFFLTDSIDMDVIFASAPELAKTELHFLAWEFNAANLLAVLLFIGAMGKSAQLFLHTWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPLFEYAPEAKMMVVYVGAVTAFFAATVGLVQNDIKRVIAYSTCSQLGYMFVAAGSGVYSVAMFHLLTHAFFKAMLFLGAGSVIHAMHHEQDMRNYGGLRKKIPFTFAIMMIGTLAITGVGIPFFSIGGVPVGFAGYLSKDAIIESAFASGNGFAFYVLVAAAGMTSFYSWRLIFLTFYGEARGDHHKHDHAHESPAVMLAPLALLAVGSVLAGMVWYHSFFGDKVASFFNLPAAAHGEAHGTEHATEGHVPEAAMTAEAAHEAAMAGTMAMAEPAAEHAVAKAPQGAIFMAETNHVIHDAHGVPDWVKLSPFGAMVTGFFFAWLYYIGDKPLPGRTARALPGLYRFLLNKWYFDELFDLLFVNPAKSLGRKLWKGGDGAVIDGAINGLALGWIPFFTRVAGRIQSGYLFHYAFAMVLGIVALMFWVVRTGGMN
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
P50939
A6LEM6
MIAB_PARD8
tRNA-i(6)A37 methylthiotransferase
Parabacteroides
MVNQENGVDLKSATQSDERKLFIETYGCQMNVADSEVVASIMKMDGYSMTENIEEADAIFVNTCSVRDNAEQKIYGRLQYFQSLKRKKKSLIVGVLGCMAERVKEDLIHVHHADLVVGPDSYLDLPNLVGAVEHGEKAINVELSTQETYKDVIPLKLPGVHISGFVSIMRGCNNFCTYCIVPYTRGRERSRDIESILNEIRDMHEKGFKEVTLLGQNVNSYSFEKEGETITFPILLDRVAKEVPDMRIRFTTSHPKDMSDDTLRVIAANDNICKFIHLPAQSGSSRILKVMNRKYTREWYLDRIAAIRRIVPDCAISTDLFCGFHSETEEDYQETLSLMREVGYDSAFLFKYSERPGTYAASHLEDNVPEEEKVRRLQGMIDLQNKLSEESNLRDIGKTFEVLIEGFSKRSREQLFGRTSQNKVVIFDKKNYHVGQFIKVKIHKASSATLFGEPVEE
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
A6LEM6
A3PH14
ILVC_CERS1
Ketol-acid reductoisomerase type I
Cereibacter
MRVYYDRDCDINLIKDKKVAILGYGSQGHAHALNLRDSGAKNVVVALREGSPSAKKAEAEGLKVMGIAEAAAWCDLIMFTMPDELQAETYKKYVHDNLREGSAIAFAHGLNVHFGLIEPKPGVDVIMMAPKGPGHTVRGEYVKGGGVPCLVAVHNDATGKAMEIGLSYCSAIGGGRSGIIETNFRQECETDLFGEQAVLCGGLVELIRMGFETLVEAGYEPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVSGPRILPYEETKARMKAVLTDIQTGKFVRDFMQENAVGQPFFKATRRINDEHQIEQVGEKLRGMMPWISKGKMVDRARN
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
A3PH14
Q9GZM5
YIPF3_HUMAN
Protein YIPF3, 36 kDa form III
Homo
MATTAAPAGGARNGAGPEWGGFEENIQGGGSAVIDMENMDDTSGSSFEDMGELHQRLREEEVDADAADAAAAEEEDGEFLGMKGFKGQLSRQVADQMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKMVNFPQKIAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHLHALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLEGPNIPPIQRVPRDIPAMLPAARLPTTVLNATAKAVAVTLQSH
Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
Q9GZM5
Q8AA14
THIG_BACTN
Thiazole synthase
Bacteroides
MEKLVIAGREFDSRLFLGTGKFNSNEVMEQAILASGTEMVTVAMKRIDMDDKEDDMLKHIIHPNIQLLPNTSGVRDAEEAVFAAQMAREAFGTNWLKLEIHPDPRYLLPDSIETLKATEQLVKLGFIVLPYCQADPVLCKRLEEAGAATVMPLGAPIGTNKGLQTKEFLQIIIEQAGIPVVVDAGIGAPSHAAEAMELGASAVLVNTAIAVAGNPVEMALAFKAATEAGRRAYEAGLGLQADNFIAEASSPLTAFLE
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
Q8AA14
Q47745
VANS_ENTFA
Vancomycin histidine protein kinase
Enterococcus
MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRAMEAQQTVKSYQPLVELIQNSDRLDMQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNADTSNSVRPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMTTPIKALADSANKMANLKEVPPPLERKDELGALAHDMHSMYIRLKETIARLEDEIAREHELEETQRYFFAAASHELKTPIAAVSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKTISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLSDPKLIQKALSNVILNAVQNTPQGGEVRIWSEPGAEKYRLSVLNMGVHIDDTALSKLFIPFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPPTSTL
Member of the two-component regulatory system VanS/VanR. Activates the transcription of vanH, vanA and vanX in response to vancomycin which results in vancomycin resistance. VanS activates VanR by phosphorylation.
Q47745
B7VMZ9
ATPD1_VIBA3
F-type ATPase subunit delta 1
Vibrio
MSDLTTIARPYAKAAFDFAVDKGELDQWGQMLTFAAEVAQNDDVHNLLSGSMTAEKLAEVFIVICGEQFDEFGQNLIKVMAENGRLMAFPDVCKEFFILKKEYEKEIDVEVTSAVELSEEQRAEISSKLEQRLARKVQLNCSIDETLLSGVIIRAGDLVIDNSARSRLDRLSDALQS
This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
B7VMZ9
B5XL15
PYRF_STRPZ
OMP decarboxylase
Streptococcus
MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGPDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAIKAVTPTGFNCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVATYQAIKAEWAG
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
B5XL15
P41543
OST1_YEAST
Oligosaccharyl transferase subunit alpha
Saccharomyces
MRQVWFSWIVGLFLCFFNVSSAAQYEPPATWENVDYKRTIDVSNAYISETIEITIKNIASEPATEYFTAFESGIFSKVSFFSAYFTNEATFLNSQLLANSTTAPGDDGESEIRYGIIQFPNAISPQEEVSLVIKSFYNTVGIPYPEHVGMSEEQHLLWETNRLPLSAYDTKKASFTLIGSSSFEEYHPPNDESLLGKANGNSFEFGPWEDIPRFSSNETLAIVYSHNAPLNQVVNLRRDIWLSHWASTIQFEEYYELTNKAAKLSKGFSRLELMKQIQTQNMRQTHFVTVLDMLLPEGATDHYFTDLVGLVSTSHAERDHFFIRPRFPIFGGWNYNFTVGWTNKLSDFLHVSSGSDEKFVASIPILNGPPDTVYDNVELSVFLPEGAEIFDIDSPVPFTNVSIETQKSYFDLNKGHVKLTFSYRNLISQVANGQVLIKYDYPKSSFFKKPLSIACYIFTALMGVFVLKTLNMNVTN
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
P41543
Q4K4E4
YQGF_PSEF5
Putative pre-16S rRNA nuclease
Pseudomonas
MALRLILGFDYGTKQIGVAVGQAITGQARELCTLKAQNGVPDWNQVEALIKEWKPDAVVVGLPLNMDGSPSDMCVRAEKFARRLNGRFNVPFYTHDERLTTFEAKGERLARGGQKGSYRDNPVDAIAAALLLQGWLDENAGLLNT
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
Q4K4E4
Q5E7N0
DAPB_ALIF1
4-hydroxy-tetrahydrodipicolinate reductase
Aliivibrio
MVRVAIAGAAGRMGRNLIKAVNGSQFAVLAAASERPESSLIGVDVGEMAGLGKSGILIVDDLAKVTDDFDVIIDFTLPISTLKNIELCQEHNKAIVIGTTGFSEPGKEIIDQASKEIPVVMAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIVEAHHRYKVDAPSGTAIGMGEAIAGAMGNKLEDVAVYAREGITGERSKDEIGFATIRAGDIVGEHTAMFADIGERVEITHKATDRMTFANGAVRASHWLHKKEPGFYTMHDVLNLDQI
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
Q5E7N0
A8S6A4
3S11_AUSSU
Short neurotoxin 1
Austrelaps
MKTLLLTLVVVTIVCLDLGYTMTCCNQQSSQPKTTTTCAESSCYKKTWRDHRGTIIERGCGCPNVKPGIQLVCCETNECNN
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
A8S6A4
Q8NGU4
OR2I1_HUMAN
Putative olfactory receptor 2I4
Homo
MLANQASAEERFLLLGFSDWPSLQPVLFALVLLCYLLTLTGNSALVLLAVRDPRLHTPMYYFLCHLALVDAGFTTSVVPPLLANLRGPALWLPRSHCTAQLCASLALGSAECVLLAVMALDRAAAVCRPLRYAGLVSPRLCRTLASASWLSGLTNSVAQTALLAERPLCAPRLLDHFICELPALLKLACGGDGDTTENQMFAARVVILLLPFAVILASYGAVARAVCCMRFSGGRRRAVGTCGSHLTAVCLFYGSAIYTYLQPAQRYNQARGKFVSLFYTVVTPALNPLIYTLRNKKVKGAARRLLRSLGRGQAGQ
Odorant receptor.
Q8NGU4
P19963
ALL1_OLEEU
Allergen Ole e I
Olea
EDIPQPPVSQFHIQGQVYCDTCRAGFITELSEFIPGASLRLQCKDKENGDVTFTEVGYTRAEGLYSMLVERDHKNEFCEITLISSGRKDCNEIPTEGWAKPSLKFKLNTVNGTTRTVNPLGFFKKEALPKCAQVYNKLGMYPPNM
May be involved in recognition between pollen-stigma and pollen tube-style cells.
P19963
Q10PI9
PUB75_ORYSJ
RING-type E3 ubiquitin transferase PUB75
Oryza sativa
MPQYQELPCGGQVLDIDTALKDGILGGGPELGDAAAGDGGKQPVELRKMMDELDAAGDGGGDEAVPAVFICPISLEPMVDPVTLCTGQTYESANISRWLALGHRTCPTTMQELWDVTPIPNTTLRQLIAAWFSRRYTRFKKRSADFHGRAAELVHALRGTAVPKRQPLKGQARVAALRELRSLAAAHQSVTKAIAEAGGVGLLTSLLGPFTSHAVGSEAVAILVSGVPLDADAKAALMQPAKVSLLVDMLNEGAVDTKINCVRLIRILMEEKGFRPDTVASLSLLVGVMRLVRDKRHPDGVAAGLELLNSICAVHKPARSLIVSIGAVPQLVELLPELPTECVEPALDILDALAAVPEGRIALKDCPRTITNAVRLLMRVSEACTRRALSMLWVVCRMAPEECAPAALDAGLGAKLLLVIQSGCGPELKQQASELLKLCTMNCTSTVFISKCKLTKTIQ
E3 ubiquitin ligase that may function as positive regulator of brassinosteroid (BR) signaling. Possesses E3 ubiquitin ligase in vitro . Acts together with the heterotrimeric G alpha subunit GPA1 at the plasma membrane to mediate a BR signaling pathway that affects plant growth and development. Does not seem to be involved in gibberellin or cytokinin responses .
Q10PI9
Q29478
CP2CV_CAPHE
CYPIIC31
Capra
LVSTPWIELFNAFPSLLRHFPGSHNTIFKNMTEQRKFILEEIKKHQESLDLNNPQDFIDYFLIKMEKEKHNKHSEFTMDNLITTVWDVFSAGTETTSLTLRYGLLLLLKHPEVTAKVQEEIDRVVGRNRSPCMQDRSRMPYTDAVLHEIQRYIDLVPSNLPHVATQDVKFREYLIPKGTAILTSLTSVLHDGKEFPNPGQFDPAHFLDESGNFKKTDHFMAFSAGKRVCVGEGLARMELFLLLVSILQHFTLKPVVDPKHIDIAPSFKGMLSIPPFCEMCFIPV
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Q29478
Q6Y4S4
KISS1_MOUSE
Metastin45-54
Mus
MISMASWQLLLLLCVATYGEPLAKVAPLVKPGSTGQQSGPQELVNAWEKESRYAESKPGSAGLRARRSSPCPPVEGPAGRQRPLCASRSRLIPAPRGAVLVQREKDLSTYNWNSFGLRYGRRQAARAARG
Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals.
Q6Y4S4
A5WHD5
SYT_PSYWF
Threonyl-tRNA synthetase
Psychrobacter
MVAITLPDGNVKEFDGATTVMEVAQSIGPGLAKATIAGRVDGKLVDASDPITQDASVEIVTAKDKDGVDIIRHSTAHLLGHAVKQLYPNVKMVIGPVIEDGFYYDIFSEKPFTPEDMAAIEKRMAELIKQNYDVIKKMTPREEAIKIFEERGEDYKLKLIADMPEEKELGLYHHQEYVDMCRGPHVPNTRFLKVFKLMKMSGAYWRGDAKNEQLQRIYGTAWADKKDLQAYIQRIEEAEKRDHRKIGKALNLFHMQEQSPGMVFWHPNGWTIYQVLEQYMRKVQKDNGYQEIKTPQIVDRSLWEKSGHWGNYATNMFTTSSESRDYAVKPMNCPCHVQVFNQGLKSYRELPIRLAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTQAQIQEEVANFIKLTLDVYKDFGFDQIEMKLSTRPEKRVGTDESWDIAEKALADALDSSGLEWEYLPGEGAFYGPKIEFSLKDSLGRVWQCGTIQVDPNMPERLEAEFVNENNERETPIMLHRAILGSFERFLGMLIEHYAGWMPVWLAPQQVVVMNITDKQADACQNVASELQNAGLRAITDLRNEKIGFKIRERTLERIPYMLVLGDKEVESGQVNVRTREGENLGVMSVADFIELVQKAVAQKGRLTTKTDEE
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
A5WHD5
A6LLN6
IF1_THEM4
Translation initiation factor IF-1
Thermosipho
MSNKEDIIKMEGTIVEALPNAMFRVELENGHKILAHISGKMRKNFIRLVPGDKVVVELTIYDLTKGRIVYRKKS
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
A6LLN6
Q9GRC4
CEM20_MEGRO
20 kDa cement protein
Megabalanus
MKWFLFLLTTAVLAAVVSAHEEDGVCNSNAPCYHCDANGENCSCNCELFDCEAKKPDGSYAHPCRRCDANNICKCSCTAIPCNEDHPCHHCHEEDDGDTHCHCSCEHSHDHHDDDTHGECTKKAPCWRCEYNADLKHDVCGCECSKLPCNDEHPCYRKEGGVVSCDCKTITCNEDHPCYHSYEEDGVTKSDCDCEHSPGPSE
Component of the insoluble proteinaceous cement which allows underwater adhesion to rocks and other surfaces . Shows specific adsorption on calcite substrates .
Q9GRC4
Q28MJ1
COXX_JANSC
Heme O synthase
unclassified Jannaschia
MSDFTAQTTTEPREYDAGFGDYFALLKPRVMSLVVFTALVGILVAPGGVSPMIGFTAILFIALGAGASGALNMWYDADIDAVMKRTAKRPVPAGKVPAGEALTLGLWLSAISVAMLGLATNWVAAGLLAFTIFFYAVVYSMWLKRATPWNIVIGGAAGSFPPMIGWAAVTGDVSLASVLMFGIIFMWTPPHFWALALFLKKDYNNAGVPMLTVTHGRTETRRQILIYTILLVPVALGLVLTEVAGPVYLITALVCNAIFLKGAYDIWKRDEAMAEADGYAVEKKVFKFSLLYLFLHFGALLLDAIWRLI
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
Q28MJ1
Q17YG0
HEMH_HELAH
Protoheme ferro-lyase
Helicobacter
MNLAQENLNSPNNLGNNATKSPKETVILLNMGGPNSLYEVGVFLKNMFDDPFILTIKNNFMRKMVGKMIVNSRIEKSKKIYEKLGGKSPLTPITFALTERLNELDPSRFYTYAMRYTPPYASMVLQDLALKEVESLVFFSMYPQYSSTTTLSSFNDAFNALKSLETFRPKVRVIERFYASEKLNEIILNTILSTLNNHKSQDFVLIFSVHGLPKSIIDAGDTYQQECEHHVDLLKDLMRQKNIHFKQVLLSYQSKLGPMKWLEPSTEGLIEKHRKSNIIIYPLAFTIDNSETLYELEIQYRLMAARLAIKEYLVCPCLNDSIEFAKFIIELVKNLKDE
Catalyzes the ferrous insertion into protoporphyrin IX.
Q17YG0
P22302
SODF_NICPL
Superoxide dismutase [Fe], chloroplastic
Nicotiana
KFELQPPPYPMDALEPHMSSRTFEFHWGKHHRAYVDNLNKQIDGTELDGKTLEDIILVTYNKGAPLPAFNNAAQAWNHQFFWESMKPNGGGEPSGELLELINRDFGSYDAFVKEFKAAAATQFGSGWAWLAYKPEEKKLALVKTPNAENPLVLGYTPLLTIDVWEHAYYLDFQNRRPDYISIFMEKLVSWEAVSSRLKAATA
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
P22302
A7HSA5
RLME_PARL1
rRNA (uridine-2'-O-)-methyltransferase
Parvibaculum
MTNSGKTGGKSGKGGTGGARALKVRVKTARKRSNSSTRWLQRQLNDPYVHAAKREGYRSRAAFKLAEIDDKYRFLKPGGRVVDLGCAPGGWCQVAVARVKAEGGDAGAEGRHGRVIGLDYLEMDPVPGATILQLDFLSEGADDQVKELLAGEADVVLSDMAAPTTGHKQTDHMRIMSLCEIAAHFATEVLAPGGTFLAKVLRGGTENELLVLLKQHFKTVRHVKPKASRADSAEMYVLAQGFKGRSESPLDDAE
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
A7HSA5
P40985
HUL4_YEAST
HECT-type E3 ubiquitin transferase HUL4
Saccharomyces
MVSLFDKLNAKKDGRDGSVSKELLSHSVAHTKNRLPKSGRRTSERSLAASVKDGSCSNSKSNKRNSSASVSGEEDKSCLISLNCLCCGVPLRFPASITKFRCSACQVTVIVKEPEINSNLESSTHISCTLEGLQMVVRRCHDDLQRLKKTGILDKERKGLIFQPVITYLLDRFHDVSILNRSFLVHDGGKNIKMLNYEVLQRFYSILSNLPTRKPYYSMLCCCNDLLKRITINKGENLQILQYRWLLIILNIPTIRTCLIRDRKSKNVFETQQIRAVSYELAKRCIGYLSNLSTKTSQQLIQSLRRTPTDNFSYQVEILNLYINFQFSRLLSNELSNRTAKNNVKPEDEMRSRLRRHHTTGHEFLSTRPISAQSNDKQGSGFTHPVNNKMKFKFFQYEEDWHIHSAAKLTFIYYVANTRRNGRGALSIQSFYNITLDFIDYKQDFDHWRGVAQKTKMNQLIEEWGNSTTKKCFSFCKYPFILSLGIKISIMEYEIRRIMEHEAEQAFLISLDKGKSVDVYFKIKVRRDVISHDSLRCIKEHQGDLLKSLRIEFVNEPGIDAGGLRKEWFFLLTKSLFNPMNGLFIYIKESSRSWFAIDPPNFDKSKGKNSQLELYYLFGVVMGLAIFNSTILDLQFPKALYKKLCSEPLSFEDYSELFPETSRNLIKMLNYTEDNFEDVFSLTFETTYRNNNWILNDSKSSKEYVTVELCENGRNVPITQSNKHEFVMKWVEFYLEKSIEPQYNKFVSGFKRVFAECNSIKLFNSEELERLVCGDEEQTKFDFKSLRSVTKYVGGFSDDSRAVCWFWEIIESWDYPLQKKLLQFVTASDRIPATGISTIPFKISLLGSHDSDDLPLAHTCFNEICLWNYSSKKKLELKLLWAINESEGYGFR
Probable E3 ubiquitin-protein ligase, component of the TRAMP (TRF4) complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information. Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates.
P40985
Q1LTU7
MNMG_BAUCH
Glucose-inhibited division protein A
Candidatus Baumannia
MLKNYFFDVIIIGGGHAGTEAAVASAKIGCNTLLLTHNIKTIGEMSCNPAIGGIGKGHLAKEVDAMGGIMAKAIDAAGIQFRILNASKGPAVRATRAQADRYLYRKAVYNMLKNTNNLLVLQQFVENLIIKNNNVIGVISKAKDKFYANSVILTVGTFLDGKIHIGLNSYPGGRTGDLSSISLSSNLRKLPFRVKRLKTGTPPRIHASTVNFNILTKQESDNPLPVFSFTGSVSEHPRQIPCYITYTNKNTHDIIYNNLHYSPIYTKNIEGIGPRYCPSIEDKIIHFAHRDSHQIFLEPEGLMSNIIYPNGISTSLPVDIQLKIVQSIEGLEKASIIQPGYAIEYDFFDPRDLKNTLESKIINGLFFAGQINGTTGYEEAAAQGLIAGINAAKKVLEQDSWYPNRSQAYIGVLIDDLCLQGIEEPYRMFTSRAEYRLSLREDNADLRLTEIARKLGLVNENHWHKFCIKLDYIERERQRLRNLWVQPNTIGIQDLNQLLKKPIMCKINGEELLRRPEINYKTLTNLSFFQPTLKNIQAAEQIEIQIKYEGYIAQQQEQILRQLNYEQTLLPKNMDFSLVTGLSNEAISQLNNHQPYSIGQALRISGITPIAISLLLLWLKKNNLLANKINK
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
Q1LTU7
Q4PSR7
ATB22_ARATH
Homeodomain transcription factor ATHB-22
Arabidopsis
MEYWSSSFIDGASSSSFISPFYNFDHFSGNQDNRCLGTMMGAQQDILHVPLAMVESGYGEESNSFNGQEKKKKKMTSEQLKFLERSFQEEIKLNPDRKMKLNPDRKMKLSKELGLQPRQIAVWFQNRKARWKNKQLEHLYESLRQEFDIVSREKELLQEELIQLKSMIREDSSCKKKQTWEKACS
Probable transcription factor.
Q4PSR7
Q2HXI5
PCS2_CAMPL
Theobromine synthase PCS2
Camellia
MKEVKEALFMNKGEGESSYAQNSSFTETVTSMTMPVLENAVETLFSKDFHLLQALNAVDLGCAAGPTTFTVISTIKKMMEKKCRELNCQTLELQVYLNDLPGNDFNTLFKGLSSKVVGNNCEEVSCYVVGVPGSFHGRLFPRNSLHLVHSCYSVHWLTQAPKGLTSKEGLALNKGKIYISKTSPPVVREAYLSQFHEDFTMFLNSRSQEVVPNGCMVLILRGRLSSDPSDMESCFTWELLAAAIAELVSQGLIDEDKLDTFNVPSYFPSLEEVKDIVERNGSFTIDHMEGFELDSPQMQENDKWVRGEKFATVARASTEPIISNQFGHEIMDKLYEKFTHIVISDLEAKIPKVTSIILVLSKIVG
No detectable N-methyltransferase activity.
Q2HXI5
Q6BKA3
3DHQ_DEBHA
3-dehydroquinate dehydratase
Debaryomyces
MVKKILLINGPNLNSLGTREPEKYGTTTLKDIEQAAIEQAKAKGSEMAVYQNNTEGFIVDRIHEAKKQGVEYILINAGAYTHTSVAIRDALSAVAIPFIEIHITNVHSREEFRHKSYLSDTAVAVICGLGVYGYTAAIDFALNK
Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
Q6BKA3
Q9HDQ1
LEU3_WICAN
Beta-IPM dehydrogenase
Wickerhamomyces
MSEKTIVVLPGDHVGTEITNEAIKVLKAIEEVRPNVKFNFQHHLIGGAAIDATGVPLPDEALEAAKKADAVLLGAVGGPKWGTGAVRPEQGLLKIRKELNLYANLRPCNFASESLLELSPIKAEFAKGTDFTVVRELVGGIYFGERKEDDGSGVASDTETYSVPEVQRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRKTVTETIEKEFPQLTVQHQLIDSAAMILIKSPTTLNGIVITSNMFGDIISDEASVIPGSLGLLPSASLASLPDTNKAFGLYEPCHGSAPDLPANKVNPIATILSAAMMLKLSLDLFEEGVALEKAVKEVLDAGVRTGDLRGSNSTKEVGDAAVEAAKRILKN
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
Q9HDQ1
B6YSQ2
RS11_THEON
30S ribosomal protein S11
Thermococcus
MSEEQQVVNLKKKEKWGVAHIYSSYNNTIIHITDLTGAETVSRWSGGMVVKADRDEPSPYAAMIAAKRAAEEAMEKGFVGVHIKVRAPGGSKSKTPGPGAQAAIRALARAGLRIGRVEDVTPIPHDGTRPKGGRRGRRV
Located on the platform of the 30S subunit.
B6YSQ2
Q5F7G6
PYRG_NEIG1
UTP--ammonia ligase
Neisseria
MTKFIFVTGGVVSSLGKGIAAASIAAILESRGLNVTMLKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFIDSTMTRRNSFSTGQVYENVIAKERRGDYLGGTVQVIPHITDEIKRRIHEGAAGYDVAIVEIGGTVGDIESLPFLEAIRQMRSQLGRNNTLFAHLSYVPYIAAAGEIKTKPTQHTVKEMLSIGLQPDILICRMDRKMPADERRKIALFCNVEERAIVGSYDVDSIYECPEMLHDQGIDNIITEQLQLNVQQADLTAWKKIVHAVKNPKHTVKIAMVGKYVDLTESYKSLIEALKHAGIHTETDVQITFVDSESIEKNKGDVSVLKDMDAILVPGGFGSRGVEGKIAAVRYARENNVPYLGICLGMQIALIEYARDVAGLKGANSTEFDLKCAAPVVALIDEWQTADGSVETRDESADLGGTMRLGAQEVELKAGSLAVKIYGSGHIRERHRHRYEVNNNYVSALEQAGLVIGGVSAGRERLVETIELPNHPWFFACQFHPEFTSNPRKGHPLFTAFVKAALNNKKA
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
Q5F7G6
Q5GRT9
RUVC_WOLTR
Holliday junction resolvase RuvC
unclassified Wolbachia
MTRIIGLDPGMSKTGWAIIDMDERSNIEFLGSGTISTGNKLGMGERLHVIFEQLKKVISLYSPSEAAIEKIFVNKNPKSSLTLGYARGIVILVLEITELTMNEYDTNYVKKSITGNGHADKDQVIFMVKQIIKNLNIKCHHAADALAVAICHVYTKSSYFVR
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
Q5GRT9
Q8KA64
SECE_BUCAP
Protein translocase subunit SecE
Buchnera
MKIRIPDQKKAKNLEKIKWFFITAIFITSFFINNFFDKIGYFTRISIITLLVVFAISIALYTKKVKNVFVYINASKNEMKKITWPQYKETLYTTFIIISVTILISLLLWGLDSIIFRLIAFIISVRF
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Q8KA64
C1DPH8
ISPH_AZOVD
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Azotobacter
MHIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVDDLRSRGAIFVEELDQVPDNVIVIFSAHGVSQAVRQEAARRGLKVFDATCPLVTKVHMEVARYSREGRECILIGHQGHPEVVGTMGQYDTANGGAIYLVEDEEDVARLQVRNPVSLAFVTQTTLSMDDAARMIDALRARFPGIGGPRRDDICYATQNRQDAVRQLAGECQLVLVVGSSSSSNSNRLRELAESIGVPAYLVDGAQDLRREWFDGIRRVGVTAGASAPEVLVRDVIDRLRQWGVVNVEELTGREENITFSIPKELRVVSSD
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
C1DPH8
B5Z069
TRMA_ECO5E
tmRNA (uracil(341)-C(5))-methyltransferase
Escherichia
MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIALDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECSVLLTAK
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
B5Z069
P15647
BACH_NATPH
NpHR
Natronomonas
MTETLPPVTESAVALQAEVTQRELFEFVLNDPLLASSLYINIALAGLSILLFVFMTRGLDDPRAKLIAVSTILVPVVSIASYTGLASGLTISVLEMPAGHFAEGSSVMLGGEEVDGVVTMWGRYLTWALSTPMILLALGLLAGSNATKLFTAITFDIAMCVTGLAAALTTSSHLMRWFWYAISCACFLVVLYILLVEWAQDAKAAGTADMFNTLKLLTVVMWLGYPIVWALGVEGIAVLPVGVTSWGYSFLDIVAKYIFAFLLLNYLTSNESVVSGSILDVPSASGTPADD
Light-driven anion pump. Binding affinity for the anions is in the order, bromide > chloride > nitrate > azide > bromate and binding is pH dependent.
P15647
Q38XV5
RL21_LATSS
50S ribosomal protein L21
Latilactobacillus
MYAIIKTGGKQYKVEAGQAIYVEKLTAEAGEKVTFDQVILVGGETTKVGTPNIDGVTVDGTVEKQGREKKVVTFKYKPKKHSHQKKGHRQPYTKVMIDAINA
This protein binds to 23S rRNA in the presence of protein L20.
Q38XV5
Q8RXT4
NEK4_ARATH
NimA-related protein kinase 4
Arabidopsis
MERYEVLEQIGKGSFGSALLVRHKQERKKYVLKKIRLARQSDRARRSAHQEMELISTVRNPFVVEYKDSWVEKGCYVCIVIGYCQGGDMTDTIKRACGVHFPEEKLCQWLVQLLMALDYLHSNHILHRDVKCSNIFLTKEQDIRLGDFGLAKILTSDDLTSSVVGTPSYMCPELLADIPYGSKSDIWSLGCCMYEMAAHKPPFKASDVQTLITKIHKLIMDPIPAMYSGSFRGLIKSMLRKNPELRPSANELLNHPHLQPYISMVYMKLESPRRSTFPLQFSERDATLKERRRSSFSNDRRLNPSVSDTEAGSVSSSGKASPTPMFNGRKVSEVTVGVVREEIVPQRQEEAKKQSGAARTPRVAGTSAKASTQRTVFKHELMKVSNPTERRRRVSLPLVVENPYTYESDITALCSLNSPDVSVNTPRFDKIAEFPEDIFQNQNRETASRREVARHSFSSPPCPPHGEDNSNGSITKDKCTVQKRSVSEVKQRRFDTSSYQQRAEALEGLLEFSAKLLQQERYDELGVLLKPFGAERVSSRETAIWLTKSFKEASV
May be involved in plant development processes.
Q8RXT4
Q1GT68
RL1_SPHAL
50S ribosomal protein L1
Sphingopyxis
MAKLTKKQKALEGKVDAQKLHGVDEAIKLVRELATAKFDETLEIAMNLGVDPRHADQMVRGVVTLPAGTGKDVKVAVFARGDNAEKALAAGADKVGAEDLMEDMLAGNLDYGRVIATPDMMGIVGRLGKTLGPKGLMPNPKLGTVTPNVAEAVKAAKGGQIEFRVEKVGIIHAGLGKLSFGEEKLRQNFDAFVDAIVKAKPAGAKGKYVRKVALSSSMGPGVKVDTAELTGA
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
Q1GT68
Q291K8
SIN1_DROPS
Stress-activated map kinase-interacting protein 1
Sophophora
MATYSNQHWLLSHIRNSFISTDDTGMCETVMLSDDMPKHYLRKFNSSAGVESHRRRPLKPPLASALPDRNTRHPDAPMQEVDFMCYPGLDLSDDEEDMSTHSFDIQMYPEVGAHRFRSNTAQKLEKLDIAKRRAARIKSINYNEEVQPPEDKDFFMRKEIPNIKPTIPKEKKANDDELSDEGVQSMLTEQLAKSPKQTQNKFIEFARFDGTSQVGMQTKRINVYLNMLPEPDRNYPLKVCVLSTAKIQEVIGFVCYKTSLQYPDVPLKSLQHYGLYMTEDNDDMEDFPPLDNREPCSKFGFSHLTLAERRPLAPVTRVDYPGQLGNKSMTSEDDKATLADAALRALKNITLNGGAADPGGGAVGGGEGDGDGDDSPHDNVKEYEKRLLNHNDMLEAPMHRSFRLNIIDKRFFKSDVTLGISGERIEIDQYKNAKFWPQKKPVSTPIDLVAHCEIVERRHLKALLRIWLKSNSSSSSLPSGCTSAPINASVTTLNTGTGSSSAGIAHSPSSPGNSFGFFMTSNIRFKHYDFDTDTHTAEQINSKLNCILEMRSSELRREFLQQRERKQERQQVKKQLKL
Component of a multiprotein complex that phosphorylates Akt1, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes.
Q291K8
Q6G336
PURQ_BARHE
Phosphoribosylformylglycinamidine synthase subunit I
Bartonella
MKTAIIQLPGLNRDRDMVAALHHITGVEPLKIWQTESTIPDVDVIVIPGGFSYGDYLRCGAIGARTPVLQAVREKAQKGVTVIGICNGFQILLEAGLLPGTLMRNTSLKFVCREIKLEVVNVNTKFSRYYSKGQIICCPVAHHDGNYFVDSETLKQMEENEQIIFRYAENTNPNGSVNDIAGIINKAGNILGMMPHPENFIEPAHGGTDGRLFFQSALELAKG
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
Q6G336
Q28HN9
CENPL_XENTR
Centromere protein L
Silurana
MQSPTNGVSTPKDFSSARRSIQFQNTGFPQIGLASARRHTPFHHAPSKRRIPQTSPLSETVDPLKIALLLSKQWTLYSVTPMHKFSYTNLKEYARLLSAHICAEKQKGLAVEVGTELNVKATFSPLPGLKGREQDPGSILIQVLAKPQFSAAGAQDRIVWSGCFCCTFADEDTLDLLTSETLLCLPLFLVNGAEALTAMVGTWFQKAFDCSFSNLPISSRDLAWMAAMWTGYEAHEHITATEFIFSVPIEPHMDISYAIHPEDIKALWSNIHKGQDEVLAEEVDLLFQCLYTHFFRHFKIHLSATHLVKVSTSVASAHCDGKVKFLSKEYLLQVLGYLTELAINNIQY
Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.
Q28HN9
P85883
PLS3_PITAZ
Phylloseptin-8
Pithecopus
MAFLKKSLFLVLFLGLVSLSICEEEKRETEEEEYNQEDDDKSEEKRFLSLIPTAINAVSALAKHFG
Has antimicrobial activity.
P85883
Q2KDZ5
IF2_RHIEC
Translation initiation factor IF-2
Rhizobium
MTDSNDDKTLSVTGKKTLTLKPSGMSQGTVRQDMGRGRTKAVVVETRKRRPMRPEDEKPITPATPAAPVRAAEPAPAPAQARPQQSTPAPRIHQPGGQANQRPQQSYQPPRANDRPRPVVLNHLSPEEMDARRRALAESQARDAQDAIRRAEEEKRRAAEEAVRKAAEAEEAARRAVEEAARQAEAAAAAAAEPAVTAPAPAPVTAEARPNTSPRPAAPAPAARRPDADGAAARPAPGAPAAVRGRRNDGDDDDRGASRGGPARGRVVRPEPAKPVTTRPKTDEERRRGKLTITTADVDGEDAGRSRSLSAMRRRQEKFRRSQVQETREKISREVVLPETITIQELSQRMSERAVDVIKYLMKEGQMMKPGDVIDADLAELIAGEFGHTVKRVSESDVELGIFNIADVEGDRVSRPPVVTIMGHVDHGKTSLLDAIRHANVVAGEAGGITQHIGAYQVEQNGQKITFIDTPGHAAFTAMRARGAQATDIAILVVAADDSVMPQTIESINHAKAAGVPIIVAINKIDKHEADPQKVRNQLLQHEVFVESMGGETLDVEVSAKTGKNLDKLLEAVLLQAEILDLKANPNRTAEGTVIEAQLDRGRGAVATVLVQNGTLKPGQIIVAGDVWGRVRALVNDKGEHMKEAPPAMPVEVLGLSGTPQAGDKFAVVESESRAREISEYRQRLARDKAAARQSGQRGSLEQMMTQMQSTGIKEFPLVIKGDVQGSIEAIAGALEKLGTDEVRARIVHLGAGGITESDISLAEASNAAIIGFNVRANAQARQFAERQGIEIRYYNIIYDLVDDVKAAMSGLLSPERRETFIGNAEILEVFNITKVGKVAGCRVVEGKVERGAGVRLIRNDVVVHEGKLKTLKRFKDEVSEVPMGQECGMAFENYEDMRVGDVIECFRVEHITRTL
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Q2KDZ5
Q13X51
MUTS_PARXL
DNA mismatch repair protein MutS
Paraburkholderia
MGIQTATASDVAQHTPMMQQYLRIKAEHPGTLVFYRMGDFYELFFEDAEKAARLLDLTLTQRGASAGNPIKMAGVPHHAVEQYLAKLVKLGESVAICEQIGDPATSKGPVERKVVRVVTPGTLTDAALLSDKNDVYLLAMCVAHNRRGVATSVGLAWLNLASGALRLAELAPDQVAAALERIRPAEVLVADTPGDAASWTPPVNAGALTRVPVWHFDIASGTQRLCDQLEVAGLDGFGAHSLTCAWGAAGALLLYAAATQGQQLRHVRSLKVEYESEYIGLDPATRRNLELTETLRGTESPTLCSLLDTCCTTMGSRLLRHWLHHPPRESAVAQARQQAIGALLEAPPGAGVDSLRGALRQISDIERITGRLALLSARPRDLSSLRDTFIALPELRAQLAAVSPNADSLARIDASLEPPQACVELLRRAVAEEPSAMVRDGGVIARGYDAELDELRDISENCGQFLIDLETRERARTGIGNLRVEYNKVHGFYIEVTRGQTDKVPDDYRRRQTLKNAERYITPELKTFEDKALSAQERALARERSLYDALLQALLPFIPDCQRVASALAELDLLAAFGERARALDWVAPTFSPDAGIEIEQGRHPVVEAQVEQFIANDCSLTPERKLLLITGPNMGGKSTFMRQTALIALLAYVGSYVPARRAAFGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILNDATPQSLVLMDEIGRGTSTFDGLALAWAIARHLLAHNGCHTLFATHYFELTQLPAEFPQAANVHLSAVEHGHGIVFLHAVSEGPANQSYGLQVAQLAGVPNAVIRAARKHLAYLEQQSAAQPAPQLDLFAAPMPMLLEDADDERDSKAEALVPPAMQALVERLRGIDPNDLRPREALDLLYELHELAAAPDADH
This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
Q13X51
B1Z5M2
KATG2_BURA4
Peroxidase/catalase 2
Burkholderia cepacia complex
MQKKRIGKSVVAALAIIAMSAGTVAAWADGAPRTNDFWWPERLDLSPLRQHDVESNPYGKDFDYAQAFNKLDIEAVKKDIRATLTTSQDWWPADYGNYGPFFIRMAWHGAGTYRTYDGRGGAGGAQQRFEPLNSWPDNANLDKARRLLWPIKKKYGQNISWGDLMVLTGNVALESMGFQTFGFGGGREDDWQSDLVYWGAGTKFMSDNRDKNGKLEKPLAATQMGLIYVNPEGPNGNPDPVAAAKDIREAFGRMAMNDEETLALIAGGHTFGKAHGAASPDKCVGAAPAGAGVEAQGLGWANKCGTGKGADTITSGLEGAWSVDPVHFTMQYLDNLLEHDWVLTKSPAGAHQWMPKDAQDIVPDAHDPSKRHPLMMFTTDIALKVDPAYSAIAKRFQAHPEEFKLAFAKAWFKLTHRDLGPKARYLGKDVPKVDLIWQDPLPVAGYQMIGDADIAELKRRILASGVPKSELIKTAWASAASFRATDYRGGANGARIRLAPENAWAVNDPASLSKVLKSLEDIQSGFNRNRTDGKQVSLADLIVLGGSAAVEDAARKAGYDVKVPFSPGRVDATQAQTDVASFAVLEPTSDGFRNYYRKSNERSPAELMVDRASKLDLSVPEMTVLVGGLRALDANAGHSRLGVLTNRPGTLSNDFFVNLLDMSTQWTKSSSADGTYEGRDRKTGALKWTASPVDLVFGSSSELRAVAEVYASDDAHEKFVRDFVHAWTKVMNLDRFDLKRS
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
B1Z5M2
Q2J302
PIMT1_RHOP2
Protein-beta-aspartate methyltransferase 1
Rhodopseudomonas
MAASGSRHPPISDDATSFAAQRERMVAQQISARGVRDPLVLAAMRQVPREAFLPERMRDLAYDDSPLPIGHGQTISQPYIVAAMIEALQLNGGERVLEIGAGSGYAAAVLAQIAGEVTTIERIGALADKAAAALAALGIGNVQVRQGDGSRGWPPGAPYDAIVVAAGGPHLPQSLKTQLAIGGRLVMPVGADQSAQRLVRLTRTSVDDVRCEQLADVRFVPLIGDEGWASVAPEPRADRPATVRK
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Q2J302
P14848
LGB2_SESRO
Srglb2
Sesbania
MGFTEKQEALVNASYEAFKQNLPGNSVLFYSFILEKAPAAKGMFSFLKDSDGVPQNNPSLQAHAEKVFGLVRDSAAQLRATGVVVLADASLGSVHVQKGVLDPHFVVVKEALLKTLKEAAGATWSDEVSNAWEVAYDGLSAAIKKAMS
Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.
P14848
B2D2C0
DEFI_ORNCO
Defensin
Ornithodoros
MVRARRGCGCPLNQGACHRHCKSIGRRGGYCAGFLKQTCTCYRN
Antibacterial peptide mostly active against Gram-positive bacteria.
B2D2C0
P11482
TBB1_VOLCA
Beta-tubulin
Volvox
MREIVHIQGGQCGNQIGAKFWEVVSDEHGIDPTGTYHGDSDLQLERINVYFNEATGGRYVPRAILMDLEPGTMDSVRSGPYGQIFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVVRKEAESCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVVPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPTFGDLNHLISAVMSGITCCLRFPGQLNADLRKLAVNLIPFPRLHFFMVGFTPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNVKSSVCDIPPKGLKMSATFIGNSTAIQEMFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASAEEEGEFEGEEEEN
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
P11482
Q61885
MOG_MOUSE
Myelin-oligodendrocyte glycoprotein
Mus
MACLWSFSWPSCFLSLLLLLLQLSCSYAGQFRVIGPGYPIRALVGDEAELPCRISPGKNATGMEVGWYRSPFSRVVHLYRNGKDQDAEQAPEYRGRTELLKETISEGKVTLRIQNVRFSDEGGYTCFFRDHSYQEEAAMELKVEDPFYWVNPGVLTLIALVPTILLQVPVGLVFLFLQHRLRGKLRAEVENLHRTFDPHFLRVPCWKITLFVIVPVLGPLVALIICYNWLHRRLAGQFLEELRNPF
Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.
Q61885
A1WXL3
RLMM_HALHL
23S rRNA 2'-O-ribose methyltransferase RlmM
Halorhodospira
MELQGWILHCRAGYEQTLASEATMAAHERDVHGYCRARAQSAYVVFHAPAGDAPLPPQLVFARAGAGLIGELQGLPEGGRAEAIAAALPPAVGSATPWVEHPDSDAGRPLARFCRRFTGPLRHALTQTGVTSGDPQRRLRLLFPDSRHCFAGIGPREGWPSGIPRLRMPRNAPSRSVLKLEEALHRLVPENERPYPGEHAVDLGAAPGGWTWLLRERGLTVTAIDNGPLAPALADDPGVEHQRTDAFRFRPRTEVDWLVCDVVDRPQGIARLMTQWLREEWARAAIFNLKLPMRRPLETVRQALDAVRTTGARAHAAQLYHDREEITVYARRMASRNRP
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
A1WXL3
P64706
Y495_MYCBO
Transcriptional regulator Mb0495
Mycobacterium tuberculosis complex
MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAAASVFRAVRLRGPVGRDVIAGSTSLSIATVNRQVIALLEAGLLRERADLAVSGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTPRNAAGAALTSLADSADRYLQRWRRRRALWVGVTLGGAVDSATGHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAPSSSTSLYVYARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGTGQLESTVSDEAVLAAARRLRIIPGIASRTRTGGSATAITDLLRVARAGNQQAKELLAERARVLGGAVALLRDLLNPDEVVVGGQAFTEYPEAMEQVEAAFTAGSVLAPRDIRVTVFGNRVQEAGAGIVSLSGLYADPLGALRRSGALDARLQDTAPEALA
Positively regulates the expression of PE13 and PPE18.
P64706
A7N1G7
YBEY_VIBC1
Endoribonuclease YbeY
Vibrio
MAIELDLQLAVENEEGLPSEQDFQLWLDKTIPLFQPQAELTIRIVDEQESHELNHEYRGKDKPTNVLSFPFEVPPGMEMDLLGDLIICRQVVEKEAVEQNKPLLAHWAHMVVHGSLHLLGYDHIEDDEAEEMESLETEIMQGMGYEDPYIAEKE
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
A7N1G7
A3MUI7
CREN7_PYRCJ
Chromatin protein Cren7
Pyrobaculum
MDQDVAEEILNKEYEVVYEGKRFLLKPAKAWVLQPPGKPGVIVALFKLPNGKTVRKVIARLPP
A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
A3MUI7
Q5LCA5
THIC_BACFN
Thiamine biosynthesis protein ThiC
Bacteroides
MEQRIKFPRSEKVYLSGKLFPEIRVGMRKVEQVPSTTFEGEKKVITPNPHVYIYDTSGPFSDPDIEIDLKKGLPRLREEWILNRGDVEQLPEISSEYGRMRRDDGSLDHLRFEHIALPYRAKAGRHITQMAYAKQGIVTPEMEYVAIRENMNCEELGIETHITPEFVRQEIAEGRAVLPANINHPEAEPMIIGRNFLVKINTNIGNSATTSSIDEEVEKAMWSCKWGGDTLMDLSTGENIHETREWIIRNCPVPVGTVPIYQALEKVNGKVEDLTWELYRDTLIEQCEQGVDYFTIHAGIRRHNVHLAEKRLCGIVSRGGSIMSKWCLVHDRESFLYEHFDDICDILAQYDVAVSLGDGLRPGSTHDANDEAQFAELDTMGELVVRAWEKNVQAFIEGPGHVPMHKIRENMERQIEKCHNAPFYTLGPLVTDIAPGYDHITSAIGAAQIGWLGTAMLCYVTPKEHLALPDKEDVRVGVITYKIAAHAADLAKGHPGAQVRDNALSKARYEFRWKDQFDLSLDPERAFSYFHAGRHTDGEYCTMCGPNFCAMRLSRDLKKTQKQK
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
Q5LCA5
Q4VZJ4
RK20_CUCSA
50S ribosomal protein L20, chloroplastic
Cucumis
MTRIKRGYIARRRRTKIRLFASSFRGAHSRLTRTITQQKIRALASAYRDRGRQKRNFRQLWIARINAVIRSNNVDYSYSRFIHNLYKRQLLLNRKILAQIAILNRNCLYMISNEIIK
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
Q4VZJ4
B2ITM5
RF1_NOSP7
Peptide chain release factor 1
Nostoc
MAESYLLDKLKSVEQTFNELTRRLGDPDTASNPDEYQEIAKSRSSLEEVVNTYEIWKTAQEDLIGAREVYKESASDPELQEMASLEVKELEEKIEHLESRLKVLLLPRDPNDEKNIMLEIRAGTGGDEASIWAGDLMQMYTRYAQTQGWKVSLVSESRGEMGGWKEVILEIKGNDVYSQLKFEAGVHRVQRVPATESGGRVHTSTATVAIMPEVDDVEIHIDPKDIEMTTARSGGAGGQNVNKVETAVDLMHKPTGIRIFCTEERSQLQNKERAMQILRAKLYDIKLGEQQAAVTSMRRSQVGTGSRSEKIRTYNYKDNRATDHRLGQNYSLTPVLDGDLETLIQSCISLDQQERLAELATSAAN
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
B2ITM5
B8NM75
USTT_ASPFN
Ustiloxin B biosynthesis protein T
Aspergillus subgen. Circumdati
MSGTSPPTPKDHITMVDHDYSDCSEDVSLIGADREHRRSSTPDGLYQHKINRHYNPLYIAVVASLTFLITDIAGQIIVAPRLAIFEHIICKAYYTQVSGAAGTGMGDCKVEPVQSELALINGWREMFDNIPGTSYTLDRFGRKKVLLIAMVGCLLSDIWVGVVTWFPDTFPLRAVWFSGIWQLIGGGGASISSMAFAMIADSCPADLRTTAFSQVHAAVLVAELVSVPAGAALANFNPWIPVFGAAIFMVLGILFAYVVVPDVRPAGSKREGGSDGDFLSSAQESHPTWLMSIHHRWRKIVDEFRKDSSWIRDVNVLLIMASFFVCQLGRMISGITLQYAAAKFHWKFDKASLLVSLRAGVNLFVLAAIIPALSYILVKRFKLNDVVKDKRITQINGVCLIIGSFVMFLAASPGTLVFGQTVFALGFAFSVTARSFLTGMVDPMHIGTVFTGVTTMLYGGLVIGSPMLAKTLQWGLQLGGIWVGLPFLLAAVLFTLALGAISAARSY
Efflux pump; part of the gene cluster that mediates the biosynthesis of the secondary metabolite ustiloxin B, an antimitotic tetrapeptide . Probably involved in self-resistance through the export of ustiloxin B .
B8NM75
A5GAG2
KDPA_GEOUR
Potassium-translocating ATPase A chain
Geotalea
MNPYEWLETILFFVVLLALIKPFGTYMAKVFQGERTLLSPVFVPCENLLYRICGVDKDDEMGWKRYACAMLLFNLVFAVSLFAMLLLQGILPLNPQKLPAFSWPLALNTAISFTTNTNWQNYGGEAAASYFTQMFGFAVHNFTSAATGIVIAIAAIRGLVRRKSSALGNFWVDTTRCTLYILLPLSLIAAIFLVSQGVIQNFSPYKTVPLVQATSFEKPRLDAKGTPIKDAKGNPVTESVTVKEVTIPMGPVASQEAIKELGTNGGGFFNANSAHPFENPTPLSNIFEVFLILLISGGLTYTFGRMAGNTRQGWALLAVMLAILILAIGVFYRAESSGNPLVAKLGVHGINMEGKETRFGLAGSALFATATTGTSCGAVNTMHDSLTPIGGMVPLSLILLSEVIFGGVGTGLYTMLAFVVIAVFVAGLMIGRTPEYLGKKIEVREMWMSITTVLASGILVLIFSGIAMILPAGVSSMNNSGAHGLSEVLYAFASMSNNNGSAFAGLNGNTLFYNLTGAVAMLLGRFVPAVAVLAMAGGLAEKKYVPPSLGTLPTDQAPFALWLTLVILIVGALTFFPALAMGPIAEQLIMMR
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
A5GAG2
Q53B46
3SDC5_OPHHA
OH-84
Ophiophagus
MKTLLLTLVVVTIVCLDLGYTRKCLNTPLPLIYKTCPIGQDKCIKMTIKKLPSKYDVIRGCIDICPKSSADVEVLCCDTNKCNK
Acts as a beta-blocker by binding to beta-1 and beta-2 adrenergic receptors (ADRB1 and ADRB2). It dose-dependently decreases the heart rate (bradycardia), whereas conventional cardiotoxins increases it. At 100 mg/kg, intraperitoneal injection into mice provokes labored breathing, impaired locomotion, lack of response to external stimuli, and death (after 30 min).
Q53B46
B6I6Q5
FADI_ECOSE
Fatty acid oxidation complex subunit beta
Escherichia
MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLFSRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWSDGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLTDGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMSDLTLIDMHEAFAAQTLANIQLLGSERFAREVLGRAHATGEVDDSKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
B6I6Q5
A8FYR5
PNP_SHESH
Polynucleotide phosphorylase
Shewanella
MVHVNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKFEEPGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSESETLIARLIDRPIRPLFPNGFKNEVQVIITVVSVDPEINPDVISMIGTSAALAISGLPFNGPLGVARVGYTDGEYVLNPNVSQLVDSDLDLIVAGTQGAVLMVESEAAALPEEVMLGGVVYGHDQQQVVISAINELKAEASKPAWDWTAPVQDADLVAKIKDLAEAEMAAAYQIEVKQDRYTQVGVVKSAAKEALLAENPEADLREIDGLLGSLEKQVVRSRIIAGNPRIDGREPDMVRGLNVMAGVLPRTHGSALFTRGETQALVTCTLGTERDAQKVDSIMGEYTNRFMLHYNFPPYSVGETGFVGSPKRREIGHGKLAWRGINAVMPSAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTRDGITALQMDIKIEGINKEIMQIALQQAYGARVHILNVMDQAIGEHRDDISDHAPRITTLKINPEKIRDVIGKGGATIRALTEETGTTIELEDDGTVKIASANGDATKEAIRRIEEITAEVEVGTIYNGKVVRIVDFGAFVTILPGKDGLVHISQIAEERVANVSDYLQVGQEVKVKVMEVDRQGRVRLSMKEAAPKAEAAPAE
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
A8FYR5
Q57HR5
CYAY_SALCH
Iron-sulfur cluster assembly protein CyaY
Salmonella
MNDSEFHRLADTLWLAIEERLDSWDGDSDIDCEINGGVLTLSFENGSKIIINRQEPLHQVWLATKQGGYHFDLKDDEWVCDRSGETFWDLLEQAATQQAGEKVSFR
Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
Q57HR5
O22914
CP121_ARATH
Chloroplast protein 12-1
Arabidopsis
MTTIAAAGLNVATPRVVVRPVARVLGPVRLNYPWKFGSMKRMVVVKATSEGEISEKVEKSIQEAKETCADDPVSGECVAAWDEVEELSAAASHARDKKKAGGSDPLEEYCNDNPETDECRTYDN
Acts as a linker essential in the assembly of a core complex of PRK/GAPDH. Coordinates the reversible inactivation of chloroplast enzymes GAPDH and PRK during darkness in photosynthetic tissues.
O22914
C3PN29
HSLV_RICAE
ATP-dependent protease subunit HslV
spotted fever group
MSDNLSLHGTTILCLKKNEEIIIAADGQVSHGNTVLKSTARKLRTIANNKIIAGFAGSTADGLALFEKLAVKIEQHKHNLLRSAVELAKDWRSDKYLRRLEAMMIVADRSHILILTGNGDVVEPENNVAAIGSGGLFALSAARALMSYENNLTAEEIALKSMNIAADLCVFSNHNIIMEKVV
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
C3PN29
Q04599
RM01_YEAST
Mitochondrial large ribosomal subunit protein uL1m
Saccharomyces
MLSVVAIPKICVTGPARRCFFHTAKKLYADDYKPAAMSSNAPSLTKDQAKKRELKRLVQRKAEAKRPATASPLYMPVTKALRYLRAAEVGRPQSQQTINLTTLVVGERGTAPLSGSVTFPKPLRYIKIAAFTNDESKLEELREKYPNHLIGGADLVAKIKSGEISVDFDKAFATPDIVPALQSQVARILGPRGVLPSVKKGTVSDDISSLLQESLGSMPFRQRGNSISIGVGKCYFTDREILQNIISARAAFKTAVDNQKSKKPNILSKTTLSSTHGPGIVIDFA
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Q04599
C0HKR2
ALLA_AGRIP
Allatostatin-A-9
Agrotis
MLSTSLPVCFLVIGAALCAPERMQNDPDPHDSTAQGSDNHSDHIAPLAKRSPHYDFGLGKRAYSYVSEYKRLPVYNFGLGKRSRPYSFGLGKRSVDEDQTNDDQQQIMNNDLDQAALAEFFDQYDDAGYEKRARPYSFGLGKRFADDDTSEEKRARAYDFGLGKRLPLYNFGLGKRARSYNFGLGKRLASKFNFGLGKRERDMHRFSFGLGKRSADDASTEDSDNYFDV
Neuropeptide inhibitors of juvenile hormone synthesis and gut muscle contraction.
C0HKR2
Q5X7G8
YQGF_LEGPA
Putative pre-16S rRNA nuclease
Legionella
MPRGVYLGFDFGYKRIGVAVGQRLTCSASPLSTIEAKAGIPDWNTIQKVITQWNPQALIVGLPTCIDDRELYTTSAARHFAKQLHKRFSLPVHLVDERLSTVEARGYLFEQGGYRQIKKAEVDSIAACVILEQWLQQSE
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
Q5X7G8
O02721
LSHR_CALJA
Luteinizing hormone receptor
Callithrix
MKQPLLALQLLKLLLLLLLPLPPLPRALREARCCPEPCNCTPDGALRCPGPGAGLTRLSLAYLPVKVIPSQAFRGLNEVIKIEISQSDSLERIEANAFDNLLNLSEILIQNTKNLIHIEPGAFTNLPRLKYLSICNTGIRKFPDVTKIFSSETNFILEICDNLHITTIPGNAFQGMNNESITLKLYGNGFEEVQSHAFNGTTVISLVLKENVHLERIHNGAFRGATGPSILDISSTKLQALPSHGLESIQTLIATSSYSLKKLPSREKFANLLDATLTYPSHCCAFRNVPTKDYPAIFAESGQSGWDYDYGFHLPKTPRCAPEPDAFNPCEDIMGYDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCNTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQIYILTILILNVVAFIIICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKMPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFRRDFFLLLGKFGCCKHRAELYRRKDFSAYTSNYKNGFTGSSKPSQSTLKLPALHCQGTALLDKTCYKEY
Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
O02721
A1UKW4
RIR2H_MYCSK
Ribonucleotide reductase small subunit homolog
unclassified Mycobacterium
MTRTRSDSLAAGGLNWNSMPLKLFAGGNAKFWDPADIDFSRDRADWESLSNLERDWATRLCAQFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHTQVFRMWLDAVGMTDDLQCYLDDLPSYRQMFYEELPASLEALATDPSPAAQVRASATYNHVIEGMMALTGYYAWHRICVDRKVLPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWEVFENRMNELIPLALSNTDDSFALYDEIPFGFAKEEFQQYAADKGMRRFGTISSARGRALAEIDVDYSPLQLEDTFAAEDSRVLATSA
Probable oxidase that might be involved in lipid metabolism.
A1UKW4
Q9SDK9
RFA3_ORYSJ
Replication protein A 3
Oryza sativa
MDTSGPAAFVNGEILKMFVGRRVRTVVQAQREEGGLLIGQSTDGHQLTIKGASGAPMSHYVEIIGIAEPNQAIRAEVCTDFGENFDPAPFNGLCKLANGQMKDLFL
As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
Q9SDK9
B8EDS6
TDH_SHEB2
L-threonine 3-dehydrogenase
Shewanella
MKALSKLKAEKGIWLVDAPKPVMGHNDLLIKIKKTAICGTDMHIYNWDEWSQKTIPVPMVVGHEYVGEVVDIGQEVRGFKIGDRVSGEGHITCGHCRNCRAGRTHLCRNTSGVGVNREGSFAEYLVIPAFNAFKIPDDISDDLASIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVCRHVGARHVVITDVNEYRLELARKMGATRAVNVSKESLKDVMKELGMTEGFDVGLEMSGVPSAFHAMLDTMNHGGKVAMLGIPGGEMAIDWSKVIFKGLVIKGIYGREMFETWYKMASLIQSGLDISPIITHHFKIDDFQQGFDAMGSGQSGKVILSWD
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
B8EDS6
B5ZAR3
RECA_UREU1
Recombinase A
Ureaplasma
MKENDKLEKLDPIATLEAKFAKSTYFIADEIKNEKVSAISTGSIHIDQITGINGIPVGKITEIYGNESSGKTTIALQTIAECQKKGGTAVLLDLEGSFDLNYAKSLKVDLTKLIITQPQTGEQAFDMIETLIKTNSIDLIVVDSVAAMIPESEYQANMSEALMGAHARLMSKGLRKIQPLMNKSQTAIIFINQLREKINTFFGNPEMTTGGKALKFYASLRIETRKADLIKEGINKIGIKTKVTTVKNKLAPPLQTCFIDVFFGHGFDYDNEIIDFAIQYGILKKNGSWFYFDDNKIGQGREQLKNTLLKNNELFTQVSEKTLAFVNNEKINQ
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
B5ZAR3
P01036
CYTS_HUMAN
Salivary acidic protein 1
Homo
MARPLCTLLLLMATLAGALASSSKEENRIIPGGIYDADLNDEWVQRALHFAISEYNKATEDEYYRRPLQVLRAREQTFGGVNYFFDVEVGRTICTKSQPNLDTCAFHEQPELQKKQLCSFEIYEVPWEDRMSLVNSRCQEA
This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.
P01036
Q9KUR9
LPTD_VIBCH
LPS-assembly protein LptD
Vibrio
MSCFSRTFLAASISAALFAPQIQAEASVDDNRAQLPNGEQCLVNQPEPTNPGQQPINVEADKLEAINGQKATYSGNVVVVQGKKRIAADNVTLHQQENVVVAEGNVQFSDGEIKTHSTKATNHLNTDEMTLENTRYQFLCEPGRGEAVYVSKTGKAVYEIEDGSITSCPDGDNAWRMRASSIDVDQNEEIATFYNPRLEVQNVPVFYLPYLTVPIGDTRKTGFLYPTASYGSRNGYSFEVPIYWNLAPQYDLETTFNYMQKRGTQLNSVFRYLTDFGAGQIKSEYLADDQLHTELGDRWAFQYEHNGIFQQAWKFEIDYSKVSDINYFSDLDSGVGNREDGQLIQEGRATYRSDNWDSALLVRDFQLLTKDTTSTNLPYRLMPQLSYNYYAPETMKYLDLDLVSHVSRFETDARGKPSATRVHIEPGLKIPFSNTWGNWTTEARVLGTYYQQDLDKTTDAKLEESVTRVIPEIRSVAGIVLERDTVLLDDYTQTLEPKIQYLYVPEKYQDNIGLYDSTLLQTDYYGLFRSRKYSGVDRIESANQVSYGASTRFFDSNYKERLNIAFGQIFYLDSKLNPSNKNPDSTSDKTSYSAWAVEMDFNFADYLFYHGGIQYDIDSQAVQLGNSTLEYRVASGYIQANYRYVAKDYIRNTVGDSITNIDDITRDGISQAGILAGYQLSRKWSASGQYYYDLTTDEALEWLANLTYTSDCWYVGFTYSNQLKSWNGNFVTDPYATPIYENNFSFNIGIIGFGTSIGAGSSMTGVDSAGNSLGYGRPFFLNN
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
Q9KUR9
Q2SDF9
CH10_HAHCH
Chaperonin-10
Hahella
MKIRPLHERVVVRRKEEETKTAGGIVLPGNAAEKPSQGEVLAVGEGRILDNGDVRPLAVKVGDKVVFGQYAGSTVKIDGEELLIMSESDIFGVIEG
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
Q2SDF9
Q5ZXH8
NEUCH_LEGPH
UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolyzing)
Legionella
MIRKIIYVTGTRADYGLMREVLKRLHQSEDIDLSICVTGMHLDALYGNTVNEIKADQFSICGIIPVDLANAQHSSMAKAIGHELLGFTEVFESETPDVVLLLGDRGEMLAAAIAAIHLNIPVVHLHGGERSGTVDEMVRHAISKLSHYHFVATEASKQRLIRMGEKEETIFQVGAPGLDEIMQYKTSTRDVFNQRYGFDPDKKICLLIYHPVVQEVDSIKIQFQSVIQAALATNLQIICLEPNSDTGGHLIREVIQEYIDHPDVRIIKHLHRPEFIDCLANSDVMLGNSSSGIIEAASFNLNVVNVGSRQNLRERSDNVIDVDVTYDAILTGLREALNKPKIKYSNCYGDGKTSERCYQLLKTIPLHSQILNKCNAY
Involved in biosynthesis of legionaminic acid (5,7-diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into virulence-associated cell surface glycoconjugates such as lipopolysaccharide (LPS) which could be a key determinant in the ability of L.pneumophila to inhibit the fusion of phagosomes with lysosomes. LPS contains a majority alpha2,4-linked homomer of legionaminic acid. Catalyzes the conversion of UDP-N,N'-diacetylbacillosamine (Bac2Ac4Ac) into 2,4-diacetamido-2,4,6-trideoxymannose and UDP.
Q5ZXH8
A4J804
COBS_DESRM
Cobalamin-5'-phosphate synthase
Desulforamulus
MFSSLRLAISFLTIFPFYNKMADNKELAQSVSYYPLVGFLLGSIAAGVCYAMHSIGLNLAADVLGLVTIITLTGGLHQDGLMDTADGIFSGRELHRKLEIMKDSRVGAMGVIALATVLLLKIAFLFELDLAQKLTAFIMAPMAGRWAMVLAITRYPYARATGGLGACLKQAGKTQLALATLILVAGCLWLFGLPGLALLGIVFFITWLTVEFIVKRLGGMTGDTYGALGEMIETWVIFLILLGQQIRML
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
A4J804
B5FNU2
CYAY_SALDC
Iron-sulfur cluster assembly protein CyaY
Salmonella
MNDSEFHRLADALWLTIEERLDNWDGDSDIDCEINGGVLTLSFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWVCDRSGETFWDLLEQAATQQAGEKVSFR
Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
B5FNU2
P59748
PQQE_KLUIN
Pyrroloquinoline quinone biosynthesis protein E
Kluyvera
MNPSKSVTPPLWLLAELTYRCPLQCPYCSNPLDFSQQKKELTTEQWIEVFRQARAMGSVQLGFSGGEPLTRKDLPELIRAARDLGFYTNLITSGIGLTAKKLDAFADAGLDHIQISFQASDETLNAALAGSKKAFQQKLEMAKAVKAHGYPMVLNFVLHRHNIDQIDKIIDLCIELDADDVELATCQFYGWAQLNREGLLPTREQIANAEAVVADYRQRMGASGNLTNPAVRDAGLLRRAAETLHGRMGIDLPQRHADCTALPCHSARQLPVAFPSVLERTLDDIWYNSFGFNRYRGFDWMPEPCRSCDEKAKDFGGCRCQAFMLTGDADNTDPVCSKSPHHGKILEARREANCSDIKIQQLQFRNRSNSELIF
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
P59748
A3CXW9
RIBL_METMJ
Flavin adenine dinucleotide synthase
Methanoculleus
MIRVVATGTFDILHPGHLYYLEESRNLGDELSVIVARDANVKHKPRPFLPEDQRLRMIRALKPVDHALLGDLHDMFRPIAEIRPDIITLGFNQHFDEEHLRQKLRERGLDADVVRIPGYPGSLASSSKIIERILNTRGPPDPTGSHGEE
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
A3CXW9
A0PXT7
RL7_CLONN
50S ribosomal protein L7/L12
Clostridium
MTREEMIQAIKEMSVLELNELVKACEEEFGVSAAAPVAVAGVAGAVGAAEEKSEFDVVLANAGSQKIKVIKAVRELTGLGLKEAKEIVDGAPKTLKEGVAKEAAEEMKAKLEEVGATIELK
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
A0PXT7