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<|newrecord|> nctId: NCT06365268 id: APHP231139 briefTitle: Perinatal Thoraco-abdomino-pelvic Tumors Study acronym: CONTRAST overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-09 date: 2024-09 date: 2024-04-15 date: 2024-04-15 name: Assistance Publique - Hôpitaux de Paris class: OTHER briefSummary: Congenital t...
Indeed, some histologically benign tumors may have lethal potential in utero (e.g. sacrococcygeal teratomas) or even undergo malignant transformation if left untreated. In contrast, other tumors that are malignant by histological criteria may have a very good prognosis, regressing spontaneously within the first year of...
Despite advances in imaging, benign and malignant solid tumors remain a major diagnostic and prognostic challenge in the antenatal context.
The management of congenital tumors requires multidisciplinary expertise, taking into account the perinatal context, which poses specific problems, particularly in terms of therapeutic aspects, but also the frequent existence of associated malformations and/or genetic predisposition syndromes.
This study focuses on solid tumors of the thoraco-abdomino-pelvic region, the main objective being to investigate the correlation between antenatal clinical and radiological analysis and confirmed postnatal diagnosis of congenital solid truncal tumors, as well as the developmental spectrum in which they fit. conditions...
<|newrecord|> nctId: NCT06365255 id: 2022-A01453-40 briefTitle: National Epidemiological Study of the Possible Impact of Stress on Glycaemic Control in Patients With Type 1 Diabetes acronym: EPISTRESS2 overallStatus: COMPLETED date: 2023-01-17 date: 2024-02-28 date: 2024-02-28 date: 2024-04-15 date: 2024-04-17 name: Ce...
In type 1 diabetes (T1DM), studies on stress and its impact on glycaemia have led to ambiguous results, mainly because there are no solid epidemiological or experimental data in the literature. The aim of this study was to assess the impact of perceived stress on blood glucose levels in a population of subjects with T1...
<|newrecord|> nctId: NCT06365242 id: DOACS1_2024 briefTitle: Direct Oral Anticoagulants and Management of Blleding Following Dental Extractions. A Prospective Cohort Study. acronym: DOACS_1 overallStatus: COMPLETED date: 2020-07-23 date: 2021-07-27 date: 2022-12-23 date: 2024-04-15 date: 2024-04-15 name: University of ...
<|newrecord|> nctId: NCT06365229 id: 2022-P2-336-02 briefTitle: Percutaneous Unilateral Biportal Endoscopy Versus Uniportal Endoscopy for Lumbar Spinal Stenosis: Study Protocol overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-01 date: 2024-12-31 date: 2024-12-31 date: 2024-04-15 date: 2024-04-15 name: Beijing Friends...
<|newrecord|> nctId: NCT06365216 id: AXO-CLI-210c-03 id: 2023-508895-13-00 type: CTIS briefTitle: ALS Phase II Study of NX210c acronym: SEALS overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2026-02-01 date: 2026-02-01 date: 2024-04-15 date: 2024-04-15 name: Axoltis Pharma class: INDUSTRY name: ACT4ALS network ...
Two doses of NX210c (5 mg/kg and 10 mg/Kg) will be investigated, along with a placebo group which will serve as a reference. Patients will be randomized to one of 3 arms in an allocation ratio of 3:3:2.
Patients will participate up to approximately 20 weeks: up to 30 days for screening, 26 days of treatment and 3 months of follow-up. Lumbar punctures will assess cerebrospinal fluid (CSF) NfL and other key CSF biomarkers related to ALS and drug mechanism of action. Blood sampling will be drawn for safety, PK and biomar...
<|newrecord|> nctId: NCT06365203 id: Through knee amputation briefTitle: Comparative Study of Through Knee Amputation Versus Above Knee Amputation Regarding Infection Rate and Function overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-12 date: 2026-04 date: 2024-04-15 date: 2024-04-15 name: Assiut University c...
<|newrecord|> nctId: NCT06365190 id: AHMU-PD-rTMS briefTitle: Effects of a Periodic Repetitive Transcranial Magenetic Stimulation in Parkinson Disease overallStatus: ACTIVE_NOT_RECRUITING date: 2020-04-06 date: 2024-07-31 date: 2024-07-31 date: 2024-04-15 date: 2024-04-16 name: Anhui Medical University class: OTHER bri...
<|newrecord|> nctId: NCT06365177 id: 29BRC22.0243 briefTitle: Evaluation of the Concordance of Five Times Sit To Stand Results Between a Physical Consultation and a Teleconsultation acronym: TELETEST overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2026-05-01 date: 2024-04-15 date: 2024-04-19 n...
It is a multicentric randomized trial in two arms :
Arm one : remote consultation then physical consultation Arm two : physical consultation then remote consultation
Consultations consist to take a Five Times Sit To Stand test, in physical consultation with physiotherapist in the same room and in remote consultation with a physiotherapist in the next room to the patient. conditions: Rehabilitation conditions: Elderly Person conditions: Teleconsultation studyType: INTERVENTIONAL pha...
<|newrecord|> nctId: NCT06365164 id: 38RC23.0354 briefTitle: Study of the Emergence of Sensory Self-awareness in Premature Newborns Using the Rooting Reflex acronym: PREMATACT overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2024-11 date: 2025-11 date: 2024-04-15 date: 2024-04-15 name: University Hospital, Grenobl...
The main hypothesis is to confirm the tactile skills of the very premature newborn in exploring the rooting reflex and then to evaluate the emergence of sensory self-awareness.
The investigators assume a difference in response in favour of a greater response of the newborn to external tactile stimulation compared to facilitated self-stimulation in favour of the distinction between self and non-self showing the emergence of a sensory awareness of self in the preterm newborn. conditions: Premat...
<|newrecord|> nctId: NCT06365151 id: TMDs fibromyalgia briefTitle: An Algorithm for Approaching Temporomandibular Disorders With Osteopathic Manual Therapy in Patients With Fibromyalgia overallStatus: RECRUITING date: 2024-04-05 date: 2025-04-05 date: 2026-04-05 date: 2024-04-15 date: 2024-04-15 name: Universitat de Ll...
<|newrecord|> nctId: NCT06365138 id: Aortic Rupture briefTitle: Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms overallStatus: RECRUITING date: 2024-01-01 date: 2029-12-01 date: 2030-12-01 date: 2024-04-15 date: 2024-04-15 name: University Hospital Augsburg clas...
<|newrecord|> nctId: NCT06365125 id: 7313E briefTitle: College Student Daily Life and Alcohol Use Study overallStatus: RECRUITING date: 2024-03-22 date: 2025-05-01 date: 2025-05-01 date: 2024-04-15 date: 2024-04-15 name: Boston University Charles River Campus class: OTHER briefSummary: Heavy alcohol use among college s...
<|newrecord|> nctId: NCT06365112 id: R21154 briefTitle: Endoscopic Acetabulum Surgery overallStatus: RECRUITING date: 2024-04 date: 2026-01 date: 2028-01 date: 2024-04-15 date: 2024-04-24 name: Tampere University Hospital class: OTHER briefSummary: Try to develop an endoscopic surgical technique to treat acetabulum fra...
<|newrecord|> nctId: NCT06365099 id: STUDY00000896_Exp2 briefTitle: Identifying Personalized Brain States Predicting Residual Corticospinal Tract Output After Stroke overallStatus: RECRUITING date: 2024-02-02 date: 2026-03-31 date: 2026-03-31 date: 2024-04-15 date: 2024-04-15 name: University of Texas at Austin class: ...
Participants will visit the laboratory for two days of testing that are separated by at least one night of sleep. On Day 1, participants will provide their informed consent. The MacArthur Competence Assessment Tool and the Frenchay Aphasia Screening Test will be used to evaluate consent capacity and confirm the presenc...
On Day 2, participants will return to the laboratory. The investigators will confirm continued eligibility and place recording electrodes on the scalp using a swim-type cap. The investigators will also place recording electrodes on the affected first dorsal interosseous as well as the affected abductor pollicis brevis ...
The investigators will recruit a total of 20 chronic stroke survivors for this study. conditions: Stroke studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 20 type: ESTIMATED name: Singl...
<|newrecord|> nctId: NCT06365086 id: STUDY00000608 briefTitle: Targeting Personalized Brain States Reflecting Strong and Weak Corticospinal Tract Output in Real-time overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-27 date: 2025-01-01 date: 2025-01-01 date: 2024-04-15 date: 2024-04-15 name: University of Texas at Aus...
Participants will visit the laboratory for one day of testing. Upon arrival, participants will provide their informed consent; afterwards, they will complete eligibility screening. The investigators will then place recording electrodes on the scalp using a swim-type cap and on the left first dorsal interosseous, abduct...
The investigators will recruit a total of 16 neurotypical adults for this study. conditions: Neurotypical Adults studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: CROSSOVER interventionModelDescription: Participants will receive single-pulse TMS during personalized brain activity patterns refle...
<|newrecord|> nctId: NCT06365073 id: TJIRB20231276 briefTitle: A Case-control Study on the Clinical Characteristics of 28-day and 90-day Death From Severe Anthrax overallStatus: RECRUITING date: 2024-03-13 date: 2024-08-31 date: 2024-12-31 date: 2024-04-15 date: 2024-04-15 name: Qin Ning class: OTHER briefSummary: This...
<|newrecord|> nctId: NCT06365060 id: 00003143 id: R01CA279808 type: NIH link: https://reporter.nih.gov/quickSearch/R01CA279808 briefTitle: Screening for AL Amyloidosis in Smoldering Multiple Myeloma overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2029-02-27 date: 2029-02-27 date: 2024-04-15 date: 2024-04-15 name:...
<|newrecord|> nctId: NCT06365047 id: STUDY00004926 briefTitle: Dry Mouth Toothpaste Study - Comparing Two Toothpastes With Arginine overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-06-01 date: 2027-06-01 date: 2024-04-15 date: 2024-04-23 name: Tufts University class: OTHER name: Colgate Palmolive briefSumm...
<|newrecord|> nctId: NCT06365034 id: YKLL-KY-2024(024) briefTitle: Study on the Efficacy and Safety of Conversion Therapy in Patients With Initially Unresectable Hepatocellular Carcinoma overallStatus: RECRUITING date: 2024-03-01 date: 2024-10-01 date: 2025-01-31 date: 2024-04-15 date: 2024-04-15 name: Qianfoshan Hospi...
<|newrecord|> nctId: NCT06365021 id: 88887.687583/2022-00 briefTitle: ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder overallStatus: RECRUITING date: 2024-05 date: 2025-08 date: 2026-08 date: 2024-04-15 date: 2024-04-15 name: Beny Lafer class: OTHER briefSummary: The goal of this clinical trial is to ...
* The efficacy of ACT in reducing depressive symptoms in patients with BD.
* The efficacy of ACT in improving the quality of life in patients with BD.
* The efficacy of ACT in improving functionality in patients with BD.
* The efficacy of ACT in improving sleep quality in patients with BD.
* The efficacy of ACT in improving psychological flexibility in patients with BD
Participants in the clinical group will undergo 12, 2 hours, weekly sessions of Acceptance and Commitment Therapy, in addition to their regular pharmacological treatment.
Participants in the control group will undergo 3, 2 hours, weekly sessions of Bipolar Disorder Psychoeducation Therapy, in addition to their regular pharmacological treatment.
Scales and assessments will be used to measure study outcomes on 3 different time-points: pre-intervention (month 0), post-intervention (month 3) and follow-up (month 6). Mood scales will be assessed every 2 weeks for the duration of treatment and every 4 weeks during the additional 12 week follow-up period. Psychologi...
Results will be compared among both groups to assess the effectiveness of Acceptance and Commitment Therapy as an intervention for syndromic and sub-syndromic depression in bipolar disorder. conditions: Bipolar Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpo...
<|newrecord|> nctId: NCT06365008 id: SYSKY-2024-210-01 briefTitle: Sintilimab Plus FOLFIRI as Salvage Therapy for Patients With Advanced Gastric Cancer overallStatus: RECRUITING date: 2024-04-08 date: 2027-04-08 date: 2027-09-30 date: 2024-04-15 date: 2024-04-15 name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen Univer...
<|newrecord|> nctId: NCT06364995 id: JKEUPM-2023-1364 briefTitle: Effects of Specialised Physical Education in Volleyball on Middle School Students' Physical Fitness and Performance overallStatus: RECRUITING date: 2024-01-10 date: 2024-06-28 date: 2024-07-05 date: 2024-04-15 date: 2024-04-16 name: Universiti Putra Mala...
Recent trends have highlighted a decline in physical fitness among youth, as evidenced by rising obesity rates and increasing failure rates in fitness assessments. To counteract this, the Ministry of Education of the People's Republic of China 2021 has initiated a shift towards "specialised physical education," integra...
Therefore, this study chose volleyball specialised physical education as an intervention to study the effect of physical fitness and The PE entrance examination for senior high school performance of middle school students. conditions: Physical Fitness conditions: Performance studyType: INTERVENTIONAL phases: NA allocat...
<|newrecord|> nctId: NCT06364982 id: PER-ECL-2023-05 briefTitle: Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease. overallStatus: NOT_YET_RECRUITING date: 2024-04-05 date: 2024-12-31 date: 2024-12-31 date: 2024-04-15 date: 2024-04-15 name: Universitat Internacional de Catalunya class: OTHER...
<|newrecord|> nctId: NCT06364969 id: 2021-06-02 briefTitle: Investigation of the Pruritogens of Liver-related Diseases overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2025-08-01 date: 2025-08-01 date: 2024-04-15 date: 2024-04-16 name: Peking University class: OTHER briefSummary: This study hopes investigate th...
<|newrecord|> nctId: NCT06364956 id: SYSKY-2024-124-02 briefTitle: Phase Ib/II Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma overallStatus: RECRUITING date: 2024-05 date: 2025-06 date: 2026-06 date: 2024-04-15 date: 2024-04-15 name: Sun ...
This study will adopt a 3+3 design and include two predefined dose groups of palbociclib: 100mg QD, 125mg QD. Initially, Tislelizumab, 200 mg administered by intravenous infusion on Day 1 of each 21-day will be administered in combination. The trial will use the first cycle (28 days) as the observation period for toler...
This study provide further evidence for improving the efficacy of neoadjuvant treatment forplatinum-refractory cT2-4aN0M0 bladder urothelial carcinoma and to offer new options for precision treatment of bladder cancer. conditions: Bladder Cancer studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NON_RA...
<|newrecord|> nctId: NCT06364943 id: 202400020B0 briefTitle: Tear Ferning Test for Dry Eye Diagnosis overallStatus: RECRUITING date: 2024-04-05 date: 2025-01-05 date: 2025-04-04 date: 2024-04-15 date: 2024-04-15 name: Chung Shan Medical University class: OTHER briefSummary: Application of tear ferning test for clinical...
<|newrecord|> nctId: NCT06364930 id: SGLT2i_HBV Study briefTitle: SGLT2i to Prevent of Liver Complications in Patients With CHB and Diabetes Mellitus overallStatus: RECRUITING date: 2024-03-26 date: 2030-10-31 date: 2031-03-30 date: 2024-04-15 date: 2024-04-15 name: Chinese University of Hong Kong class: OTHER briefSum...
<|newrecord|> nctId: NCT06364917 id: IRB-300012781 (UAB2432) briefTitle: DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC overallStatus: NOT_YET_RECRUITING date: 2024-10-31 date: 2027-01-30 date: 2027-06 date: 2024-04-15 date: 2024-04-26 name: University of Alabama at Birmingham class: OTHER briefSummary: The pu...
<|newrecord|> nctId: NCT06364904 id: SYSKY-2024-123-02 briefTitle: An Phase III Study, Multicenter,Randomized Controlled Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Uroth...
<|newrecord|> nctId: NCT06364891 id: VMMC NEXUS briefTitle: Assessing the Impact of a Digital VMMC Platform acronym: VMMC NEXUS overallStatus: RECRUITING date: 2023-10-01 date: 2024-12-31 date: 2024-12-31 date: 2024-04-15 date: 2024-04-15 name: University of Alabama at Birmingham class: OTHER name: Centre for Infectiou...
The objective of this study is to evaluate the effect of a segment-targeted mobilization intervention supported by the VMMC NEXUS Digital Mobilization Tool on the uptake of VMMC services at 30 intervention sites, compared with 30 control sites.
The research questions are:
1. What is the effect of segment-targeted mobilization interventions designed to address the specific psycho-behavioral barriers each of the seven segments face, supported by the VMMC NEXUS Digital Mobilization Tool, on the overall numbers of men receiving VMMC in each site?
2. What is the effect of the same on the numbers of men by segment receiving VMMC in each site?
3. What is the effect of the same on the numbers of men by age receiving VMMC in each site?
Secondary goals will be the following, to the extent possible:
* Assess the incremental cost of the intervention, including by MC
* Assess and document process learnings from the intervention
* Develop a workplan to enable national and regional scale-up of the mobilization model and NEXUS Digital Mobilization Tool if demonstrated as effective conditions: Voluntary Medical Male Circumcision studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: C...