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* at least once, 2 to 28 days before the treatment starts in both groups, to confirm they can take part in this study |
* on Day 1, and will stay at the clinic until Day 12 in Group 1 and Day 16 in Group 2 |
* once, 7 to 10 days later from last dose of BAY2927088 in both groups, for a health check up |
During the study, the doctors and their study team will: |
* perform physical examinations |
* collect blood samples from the participants to measure the levels of BAY2927088 |
* check participants' health by performing tests such as blood and urine tests, and checking heart health using an electrocardiogram (ECG) |
* ask the participants questions about how they are feeling and what adverse events they are having An adverse event is any medical problem that a participant has during a study. The study doctors keep track of all adverse events, irrespective if they think it is related or not to the study treatment. conditions: Advan... |
<|newrecord|> nctId: NCT06348875 id: CLN-PLAN-102v1 briefTitle: Clinical Evaluation of Radiation Reduction for Optimized Safety acronym: CERROS overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2024-07-15 date: 2024-07-31 date: 2024-04-05 date: 2024-04-05 name: Angiowave Imaging class: INDUSTRY briefSummary: The... |
<|newrecord|> nctId: NCT06348862 id: 323/REC/2023 briefTitle: Assessment of Stress and Anxiety for Patients Undergoing MRI Using, Holy Quran, Music, and Natural Sounds overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2024-06-30 date: 2024-06-30 date: 2024-04-05 date: 2024-04-05 name: Al-Quds University class: O... |
<|newrecord|> nctId: NCT06348849 id: 0797-11/2023 briefTitle: The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-06 date: 2024-07 date: 2024-04-05 date: 2024-04-05 name: Alexandria University class: OTHER briefSummary: The aim o... |
<|newrecord|> nctId: NCT06348836 id: 2123624-1/2 briefTitle: The Effects of Open Chain Versus Closed Chain Strengthening on Dynamic Valgus During a Step Down Test overallStatus: RECRUITING date: 2024-03-22 date: 2025-02-28 date: 2025-02-28 date: 2024-04-05 date: 2024-04-05 name: Alvernia University class: OTHER briefSu... |
* In individuals with abnormal knee motion and without knee pain, does a weight-bearing exercise program reduce abnormal knee motion during a step-down test better than a non weight-bearing exercise program? Participants will |
* Perform a stepdown test while undergoing motion analysis and electromyograph (EMG) recording. |
* Participants will then be placed either into a weight-bearing or non weight-bearing exercise group. Exercises will be performed 3 times per week for 6 weeks. |
* Further motion analysis and EMG data will be collected to test for differences. Researchers will compare individual results before and after exercise, and between-group results before and after exercise to see if one exercise program helps improved abnormal knee motion more than the other. conditions: Dynamic Knee Va... |
<|newrecord|> nctId: NCT06348823 id: BritishUE briefTitle: Relationship Between Soft Tissue Volume and Gingival Phenotype: A Novel Classification System overallStatus: RECRUITING date: 2024-02-25 date: 2024-06 date: 2024-10 date: 2024-04-05 date: 2024-04-09 name: Ain Shams University class: OTHER name: British Universi... |
<|newrecord|> nctId: NCT06348810 id: DTT2024 briefTitle: Dual-Task Training for People With Mild Cognitive Impairment and Mild Dementia acronym: DTT overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-01-15 date: 2025-01-15 date: 2024-04-05 date: 2024-04-05 name: Taipei Medical University class: OTHER briefSu... |
Therefore, this study aims to analyze the effect of dual-task training in improving global cognitive function, executive function, working memory, sleep, behavioral disturbances, balance, and flexibility among people with mild cognitive impairment and mild dementia. |
The main questions it aims to answer are: |
1. . Does dual-task training affect primary outcomes (global cognitive function, executive function, and working memory) |
2. . Does dual-task training affect secondary outcomes (including sleep quality, behavioral disturbances, balance, and flexibility) for people with mild cognitive impairment and mild dementia?" |
The length of dual-task training is 6 weeks; sessions are 3 times per week, each session lasts 45 minutes, and total sessions are 18. While the control group receives the usual care. Researchers will compare the experiment and control groups to see the effect of the dual-task training. conditions: Dementia conditions: ... |
<|newrecord|> nctId: NCT06348797 id: BHP01-01 briefTitle: Phase I Clinical Study of α-PD-L1/DLL3 CAR-T in Patients With R/R SCLC overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-07-31 date: 2026-12-31 date: 2024-04-05 date: 2024-04-05 name: Sichuan University class: OTHER name: Chengdu Brilliant Pharmaceut... |
<|newrecord|> nctId: NCT06348784 id: 11 briefTitle: Screening for Ovarian Malignancy overallStatus: COMPLETED date: 2022-01-01 date: 2023-01-01 date: 2023-01-01 date: 2024-04-05 date: 2024-04-05 name: Ain Shams Maternity Hospital class: OTHER briefSummary: Ovarian cancer is the second most common gynecologic malignancy... |
<|newrecord|> nctId: NCT06348771 id: Pro2023001579 briefTitle: Postprandial Inflammation and Nuts (PIN) in Older Adults acronym: PIN overallStatus: RECRUITING date: 2024-03-25 date: 2024-10-30 date: 2025-01-30 date: 2024-04-05 date: 2024-04-05 name: Rutgers, The State University of New Jersey class: OTHER briefSummary:... |
<|newrecord|> nctId: NCT06348758 id: KAP towards AI briefTitle: Knowledge, Attitudes, And Perceptions of a Group of Egyptian Dental Students Towards Artificial Intelligence acronym: AIKnowledge overallStatus: ENROLLING_BY_INVITATION date: 2024-02-11 date: 2024-06-07 date: 2024-08-07 date: 2024-04-05 date: 2024-04-05 na... |
To the best of the author's knowledge, there is no study about Egyptian dental students' views and attitudes regarding the application of AI in dental practice. Therefore, this study aimed to evaluate the attitudes and perceptions of a group of dental students in Egypt towards AI. conditions: Health Knowledge, Attitude... |
<|newrecord|> nctId: NCT06348745 id: diaphragmatic ultrasound briefTitle: Trans Thoracic Ultrasound to Assess Diaphragmatic Function in Stable COPD Versus Bronchial Asthma. overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2026-05-01 date: 2024-04-05 date: 2024-04-08 name: Assiut University clas... |
* Assessment of presence of correlation between diaphragmatic dysfunction and pulmonary function. |
* Assessment of possible association between diaphragmatic dysfunction and presence of reversibility in pulmonary function post bronchodilator. conditions: Diaphragm studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SCREENING masking: SINGLE whoMasked: PARTICIPANT c... |
<|newrecord|> nctId: NCT06348732 id: biomarkers in cardiomyopathy briefTitle: Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2025-09 date: 2025-11 date... |
<|newrecord|> nctId: NCT06348719 id: 35RC21_9732_ROBOT-ECO-GYN briefTitle: Medico-economic Evaluation of Robot-assisted Laparoscopy Compared With Conventional Laparoscopy in Hysterectomy for Endometrial Cancer. acronym: ROBOT-ECO-GYN overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-10 date: 2027-10 date: 2024... |
Since 2010 and the arrival of robotic surgery in gynaecology, the robot-assisted laparoscopic approach has gradually been used for endometrial cancer Hysterectomy. |
Several studies have suggested that the cost and effectiveness of laparoscopy may vary according to the age and body mass index of the patient. |
The investigators therefore hypothesise that robot-assisted laparoscopy may be more efficient than conventional laparoscopy for endometrial cancer hysterectomy in the context of an advanced learning curve in France. |
The investigators therefore hypothesise that robot-assisted laparoscopy could be more efficient than conventional laparoscopy for endometrial cancer hysterectomy in the context of an advanced learning curve in France. The investigators will also test the efficiency of the surgical technique as a function of age and Bod... |
This research will therefore consist of 3 complementary studies : |
A multicenter, parallel-group, open-label, randomized controlled superiority trial (ratio 1:1) comparing two groups: |
* Group 1: laparoscopic robot-assisted hysterectomy |
* Group 2: conventional laparoscopic hysterectomy A prospective cohort based on the randomized controlled trial A retrospective cohort primaryPurpose: OTHER masking: NONE count: 1680 type: ESTIMATED name: Robot-assisted laparoscopy name: conventional laparoscopy name: Prospective cohort study name: Retrospective cohort... |
<|newrecord|> nctId: NCT06348706 id: Ain Shams University25032024 briefTitle: Effect of Dipeptidyl Peptidase- 4 Inhibitors on Non-Alcoholic Steatohepatitis and Type 1 Diabetes overallStatus: COMPLETED date: 2022-11-10 date: 2023-12-01 date: 2024-01-15 date: 2024-04-05 date: 2024-04-05 name: Ain Shams University class: ... |
To the best of our knowledge, no previous study assessed the role of DPP-4 inhibitors in adolescent patients with T1DM and NASH. |
Objectives: This randomized-controlled clinical trial assessed the impact of the oral DPP-4 inhibitor, vildagliptin, as an add-on therapy on NASH in adolescents with T1DM as well as its effect on glycemic control, lipid profile, MMP-14 levels and CIMT as a marker for subclinical atherosclerosis. |
Methods: This study included 60 adolescents with T1DM and NASH with a mean age 15.6 ± 2.08 years and disease duration ≥ 5 years. Forty age- and sex-matched healthy subjects with a mean age 14.9 ± 3.2 years were enrolled as healthy controls to compare MMP-14 levels. T1DM patients were randomly assigned to receive oral v... |
<|newrecord|> nctId: NCT06348693 id: Gliotherapy briefTitle: Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness overallStatus: RECRUITING date: 2017-04-19 date: 2025-11-21 date: 2025-11-21 date: 2024-04-05 date: 2024-04-05 name: Fondazione IRCCS Ca' ... |
S1P is an intermediate of sphingolipid metabolism, formed from sphingosine through the action of sphingosine kinases (SK). Increasing evidence suggests that S1P acts as a tumor-promoting signal, predominantly in the extracellular environment, regulating important cellular properties correlated with tumor potential. |
The project aims to identify new molecular and metabolic targets involved in the survival and chemo-resistance of tumor stem cells in relation to the tumor microenvironment. conditions: Glioblastoma conditions: Glioma conditions: Glioma Glioblastoma Multiforme studyType: OBSERVATIONAL observationalModel: OTHER timePers... |
<|newrecord|> nctId: NCT06348680 id: AmasyaU-betuluzun-004 briefTitle: The Effect of Video-assisted Episiotomy Repair Training on Anxiety and Self-efficacy Levels in Midwifery Students overallStatus: NOT_YET_RECRUITING date: 2024-03-25 date: 2024-04-05 date: 2024-05-15 date: 2024-04-05 date: 2024-04-05 name: Amasya Uni... |
<|newrecord|> nctId: NCT06348667 id: 3184794 briefTitle: Effects of a Short- and Long-term 'Blackboard' Intervention on Ankle Stability in Older Adults overallStatus: RECRUITING date: 2024-03-07 date: 2024-06-10 date: 2024-06-10 date: 2024-04-05 date: 2024-04-05 name: University of Valencia class: OTHER briefSummary: T... |
The main questions it aims to answer are: |
1. Can the addition of BB exercises improve ankle dorsiflexion mobility? |
2. Can the addition of BB exercises enhance single-leg stability and control of mediolateral displacement of the center of pressure? |
Participants will be divided into control and intervention groups. Both groups will receive their usual conventional physiotherapy exercises. The intervention group will undergo a 5-week program comprising 10 sessions of BB exercises targeting ankle mobility and balance. |
Participants will be asked to: |
* Perform 3 sets of 15 repetitions for assisted ankle dorsiflexion mobility. |
* Engage in 5 rounds of 40-second balance exercises using the BB. |
Researchers will compare the intervention group's outcomes with those of the control group to determine the effectiveness of adding BB exercises in improving foot and ankle parameters related to fall prevention. conditions: Fall studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL pri... |
<|newrecord|> nctId: NCT06348654 id: 6392 briefTitle: New Digital Person-based Care Model in Patients With HER2-negative Advanced Breast Cancer acronym: InPERSON overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2024-12-01 date: 2025-01-01 date: 2024-04-05 date: 2024-04-05 name: Fondazione Policlinico Universita... |
The care pathway of patients with this type of disease represents an optimal setting for the implementation of an innovative narrative medicine pathway that, aided by integrative therapies, aims to support and accompain them in their treatment journey with a continuum of care. Moreover, the narrative medicine platform ... |
<|newrecord|> nctId: NCT06348641 id: 2011-KAEK-25 2022/12-11 briefTitle: Reducing Pain and Increasing Comfort During a Retinopathy of Prematurity Examination overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2025-04-20 date: 2025-04-20 date: 2024-04-05 date: 2024-04-05 name: Nurgül Tekin class: OTHER briefSummar... |
This was randomised-controlled study in the NICU at the Health Sciences University Bursa High Specialization Training and Research Hospital, Bursa, Turkey. The population of the study will consist of preterms hospitalized in the neonatal intensive care unit during the time period of the study. In the calculation of the... |
Case report form, PIPP=Premature Infant Pain Scale and Premature Infant Comfort Scale (PBIQ) will be used to collect the study data. Patients included in the study will be examined by the same ophthalmologist. |
The infant massage to be applied before the examination will be applied by a single nurse=researcher. Video recordings will be taken before and during the ROP examination and evaluations will be made by two neonatal nurses other than the researcher. |
Infants will be massaged by the researcher in accordance with IAIM guidelines and massage techniques. Total massage time will be equal for each infant. |
The researcher has an IAIM infant massage certificate. Before starting the infant massage, jewelry will be removed and hands will be washed. In the study, leg and face massage will be applied among the massage techniques in the IAIM guidelines. conditions: Pain conditions: Retinopathy of Prematurity conditions: Prematu... |
<|newrecord|> nctId: NCT06348628 id: P/38/04/2021 briefTitle: Motivational Interviewing in the Management of Non Alcoholic Fatty Liver Disease overallStatus: ACTIVE_NOT_RECRUITING date: 2022-05-31 date: 2025-01 date: 2025-07 date: 2024-04-05 date: 2024-04-05 name: Madunil Anuk Niriella class: OTHER briefSummary: The go... |
<|newrecord|> nctId: NCT06348615 id: DEFBODY briefTitle: Study Aimed at Evaluation of the Effectiveness and Tolerability of an Anti-cellulite Cream Medical Device acronym: DEFBODY overallStatus: RECRUITING date: 2024-01-23 date: 2024-04-23 date: 2024-06-07 date: 2024-04-05 date: 2024-04-08 name: ICIM International S.r.... |
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