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11,574,180 | Effect of hormone replacement therapy on lipids in perimenopausal and early postmenopausal women. | Maturitas | Maturitas | 39 | 3 | 10.1016/s0378-5122(01)00224-9 | eng | 2,001 | 9 | 28 | null | null | null | [OBJECTIVE] To determine the effects of oral sequential hormone replacement therapy (HRT) on lipid-profile in perimenopausal and early postmenopausal women. [METHODS] We performed a single-center, randomized, placebo-controlled trial. The trial was double blind with respect to 17beta-estradiol/desogestrel (17beta-E-D) ... | null | 0.815 | 136 | Biochemistry, Genetics and Molecular Biology; Obstetrics and Gynecology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,574,089 | Preservation of the inferior mesenteric artery in colorectal resection for complicated diverticular disease. | American journal of surgery | Am J Surg | 182 | 2 | 10.1016/s0002-9610(01)00681-x | eng | 2,001 | 8 | null | null | null | null | [BACKGROUND] Preservation of the inferior mesenteric artery (IMA) and consequential blood flow to the rectum would reduce the risk of leakage of a colorectal anastomosis. [METHODS] One hundred and sixty-three patients undergoing left colectomy for complicated diverticular disease of the colon were randomly placed into ... | null | 1.205 | 173 | Medicine; Surgery | Medicine | 2,001 |
11,574,048 | Antinociceptive and antiedematogenic properties and acute toxicity of Tabebuia avellanedae Lor. ex Griseb. inner bark aqueous extract. | BMC pharmacology | BMC Pharmacol | 1 | null | 10.1186/1471-2210-1-6 | eng | 2,001 | null | null | 2,001 | 9 | 13 | [BACKGROUND] Tabebuia avellanedae is a tree from the Bignoniaceae family. Commonly know as "pau d'arco" in Brazil, its inner bark is used as analgesic, anti-inflammatory, antineoplasic and diuretic at the Brazilian northeast. A validation of the plant usage has not been previously performed. [RESULTS] Antinociceptive a... | null | null | null | null | null | null |
11,573,900 | Elevated soluble CD26 levels in patients with tuberculous pleurisy. | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | Int J Tuberc Lung Dis | 5 | 9 | null | eng | 2,001 | 9 | null | null | null | null | [SETTING] Several reports have shown that tuberculous infection elicits a Th1-like immune response with increased levels of IFN-gamma. Recently, expression of CD26 on CD4+ lymphocytes has been shown to correlate with the production of Th1-like cytokines. We therefore hypothesized that CD26 expression might increase in ... | null | 1.354 | 124 | Infectious Diseases; Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,001 |
11,573,862 | Cilostazol for prevention of thrombosis and restenosis after intracoronary stenting. | The Annals of pharmacotherapy | Ann Pharmacother | 35 | 9 | 10.1345/aph.10253 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To evaluate the potential use of cilostazol in intracoronary stenting. [DATA SOURCES] Clinical literature was accessed through MEDLINE (1966-March 2001). Key search terms included cilostazol, intracoronary stenting, and coronary angioplasty. Abstracts of clinical trials presented at major cardiology profess... | null | 0.698 | 125 | Medicine; Pharmacology | Medicine | 2,001 |
11,573,857 | Oral bexarotene in the treatment of cutaneous T-cell lymphoma. | The Annals of pharmacotherapy | Ann Pharmacother | 35 | 9 | 10.1177/106002800103500903 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To review the preclinical and clinical information related to oral bexarotene approved by the Food and Drug Administration for the treatment of cutaneous manifestations of cutaneous T-cell lymphoma (CTCL) in patients who are refractory to at least one prior systemic therapy. [DATA SOURCES] Literature access... | null | 0.698 | 125 | Medicine; Pharmacology | Medicine | 2,001 |
11,572,263 | Tooth size and morphology in twins. | International journal of paediatric dentistry | Int J Paediatr Dent | 11 | 5 | 10.1046/j.0960-7439.2001.00289.x | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To assess concordance of tooth size and occlusal morphology in monozygotic (identical) and dizygotic (non-identical) twins compared to unrelated controls in order to determine how much these dental traits are related to inheritance. [METHODS] Mesiodistal and bucco-lingual dimensions of tooth size in 34 pair... | null | 0.281 | 81 | Dentistry | Dentistry | 2,001 |
11,571,773 | Diagnosis of dementia from the history and aetiology schedule. | International journal of geriatric psychiatry | Int J Geriatr Psychiatry | 16 | 9 | 10.1002/gps.446 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To provide a computerised method of diagnosing organic brain syndrome from history data without the use of mental state data. [METHODS] Interview dataset from participants in a community study of the incidence of dementia was used to form a training sample and validation sample. The algorithm was developed ... | null | 0.742 | 157 | Geriatrics and Gerontology; Psychiatry and Mental Health | Medicine | 2,001 |
11,571,772 | Extrapyramidal signs and cognitive abilities in Alzheimer's disease. | International journal of geriatric psychiatry | Int J Geriatr Psychiatry | 16 | 9 | 10.1002/gps.443 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To evaluate whether the relationship between extrapyramidal signs (EPS) and cognitive disturbances in Alzheimer's disease (AD) is influenced by illness duration. [METHODS] A multivariate regression analysis was used to study the relationships between EPS, illness duration and five cognitive ability areas ba... | null | 0.742 | 157 | Geriatrics and Gerontology; Psychiatry and Mental Health | Medicine | 2,001 |
11,571,749 | Chronic lymphocytic leukemia incidence is substantially higher than estimated from tumor registry data. | Cancer | Cancer | 92 | 5 | 10.1002/1097-0142(20010901)92:5<1325::aid-cncr1454>3.0.co;2-e | eng | 2,001 | 9 | 1 | null | null | null | [BACKGROUND] Although chronic lymphocytic leukemia (CLL) often is described as the most common leukemia in the U.S. and Western Europe, to the authors' knowledge the true incidence of CLL in the U.S. is unknown. CLL incidence is estimated from tumor registry reports based on tissue pathology and cancer treatment data. ... | null | 1.593 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,571,730 | Inhibition of the UCI-107 human ovarian carcinoma cell line by a targeted cytotoxic analog of somatostatin, AN-238. | Cancer | Cancer | 92 | 5 | 10.1002/1097-0142(20010901)92:5<1168::aid-cncr1435>3.0.co;2-6 | eng | 2,001 | 9 | 1 | null | null | null | [BACKGROUND] Cytotoxic analogs of somatostatin (SST), such as AN-238, which consists of 2-pyrrolinodoxorubicin (AN-201) linked to the SST carrier RC-121, can be targeted to tumors that express SST receptors. Because SST receptors are present in ovarian carcinoma cells, the authors evaluated the effect of AN-238 on the ... | null | 1.593 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,571,591 | Skeletal muscle energetics assessed by (31)P-NMR in prepubertal girls with a familial predisposition to obesity. | International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity | Int J Obes Relat Metab Disord | 25 | 9 | 10.1038/sj.ijo.0801666 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To determine whether skeletal muscle energetics, measured by in vivo (31)P-nuclear magnetic resonance spectroscopy during plantar flexion exercise, differ between multiethnic, prepubertal girls with or without a predisposition to obesity. [DESIGN] Cross-sectional study. [SUBJECTS] Girls (mean age and body f... | null | null | null | null | null | null |
11,571,448 | A pilot study of steroid-free immunosuppression in the prevention of acute rejection in renal allograft recipients. | Transplantation | Transplantation | 72 | 5 | 10.1097/00007890-200109150-00018 | eng | 2,001 | 9 | 15 | null | null | null | [BACKGROUND] Corticosteroids have been a mainstay of rejection prophylaxis for several decades, despite the multiple adverse effects of long-term use, including weight gain, hyperlipidemia, diabetes, hypertension, and bone disease. The detrimental effect of steroids on the metabolic profile begins in the early posttran... | null | 1.782 | 224 | Transplantation | Medicine | 2,001 |
11,571,327 | Language and spatial attention can lateralize to the same hemisphere in healthy humans. | Neurology | Neurology | 57 | 6 | 10.1212/wnl.57.6.1018 | eng | 2,001 | 9 | 25 | null | null | null | [BACKGROUND] Disorders of language classically occur after left brain lesions, and disorders of spatial attention after right brain lesions. It is unclear whether the hemispheric dissociation of functions is a fixed pattern of brain organization. [OBJECTIVE] The authors determined whether lateralization of language and... | null | 2.19 | 422 | Neurology | Medicine | 2,001 |
11,571,061 | A multi-dimensional analysis of cue-elicited craving in heavy smokers and tobacco chippers. | Addiction (Abingdon, England) | Addiction | 96 | 10 | 10.1080/09652140120075152 | eng | 2,001 | 10 | null | null | null | null | [AIMS] This research examined the performance of a broad range of measures posited to relate to smoking craving. [DESIGN] Heavy smokers and tobacco chippers, who were either deprived of smoking or not for 7 hours, were exposed to both smoking (a lit cigarette) and control cues. [PARTICIPANTS] Smokers not currently inte... | null | 1.243 | 224 | Medicine; Psychiatry and Mental Health | Medicine | 2,001 |
11,570,621 | Novel computer-based assessment of asthma strategies in inner-city children. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology | Ann Allergy Asthma Immunol | 87 | 3 | 10.1016/S1081-1206(10)62232-6 | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] Childhood asthma continues to be a growing medical concern in the United States, affecting > 17 million children in 1998. The mortality rate from asthma in children aged 5 to 14 years has nearly doubled, from 1.7 deaths per million to 3.2 deaths per million between 1980 and 1993. [OBJECTIVE] To evaluate th... | null | null | null | null | null | null |
11,570,578 | Comparison of Alu-PCR, microsatelite instability, and immunohistochemical analyses in finding features characteristic for hereditary nonpolyposis colorectal cancer. | Journal of cancer research and clinical oncology | J Cancer Res Clin Oncol | 127 | 9 | 10.1007/s004320100261 | eng | 2,001 | 9 | null | null | null | null | [PURPOSE] To evaluate and compare alterations detected by Alu-PCR, microsatellite instability (MI), and absence of hMLH1 and hMSH2 protein expression measured by immunohistochemical (IHC) analyses as features characteristic of hereditary nonpolyposis colorectal cancer (HNPCC). [METHODS] Alu-PCR, MI, and IHC analyses we... | null | 0.705 | 114 | Medicine; Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,568,672 | Progressive fluctuant hearing loss, enlarged vestibular aqueduct, and cochlear hypoplasia in branchio-oto-renal syndrome. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology | Otol Neurotol | 22 | 5 | 10.1097/00129492-200109000-00014 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To study the results of petrosal bone imaging and audiometric long-term follow-up of two patients with branchio-oto-renal (BOR) syndrome and relate them to the clinical features, including caloric responses. [STUDY DESIGN] Longitudinal case study. [SETTING] Tertiary referral center. [PATIENTS] A father and ... | null | null | null | null | null | null |
11,568,191 | Total knee arthroplasty in patients with ankylosing spondylitis. | The Journal of bone and joint surgery. American volume | J Bone Joint Surg Am | 83 | 9 | 10.2106/00004623-200109000-00003 | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] Ankylosing spondylitis is a seronegative spondyloarthropathy that primarily affects the sacroiliac joints, spine, hips, and, less commonly, the knee joints. The purpose of this study was to evaluate the results in a consecutive group of patients with ankylosing spondylitis who underwent total knee arthropl... | null | null | null | null | null | null |
11,568,077 | Gelatin sheet incorporating basic fibroblast growth factor enhances healing of devascularized sternum in diabetic rats. | Circulation | Circulation | 104 | 12 Suppl 1 | 10.1161/hc37t1.094544 | eng | 2,001 | 9 | 18 | null | null | null | [BACKGROUND] Poor healing of the sternum often limits the use of bilateral internal thoracic arteries (BITAs) after coronary bypass surgery in diabetic patients. We have reported that a gelatin sheet that incorporates basic fibroblast growth factor (bFGF) accelerates sternal healing after BITA removal in normal rats. T... | null | 5.548 | 691 | Cardiology and Cardiovascular Medicine; Physiology | Medicine | 2,001 |
11,567,968 | A role for methotrexate in the management of non-infectious orbital inflammatory disease. | The British journal of ophthalmology | Br J Ophthalmol | 85 | 10 | 10.1136/bjo.85.10.1220 | eng | 2,001 | 10 | null | null | null | null | [AIM] To evaluate the clinical usefulness of methotrexate for patients with non-infectious orbital inflammatory disease who fail to respond to systemic corticosteroids and/or orbital irradiation. [METHODS] The medical records of patients with non-infectious orbital inflammatory disease who were treated with methotrexat... | null | 1.26 | 185 | Ophthalmology; Sensory Systems; Cellular and Molecular Neuroscience | Medicine; Neuroscience | 2,001 |
11,567,961 | Non-cycloplegic screening for amblyopia via refractive findings with the Nikon Retinomax hand held autorefractor in 3 year old kindergarten children. | The British journal of ophthalmology | Br J Ophthalmol | 85 | 10 | 10.1136/bjo.85.10.1179 | eng | 2,001 | 10 | null | null | null | null | [AIMS] To assess non-cycloplegic screening for amblyopia with the hand held Nikon Retinomax autorefractor in 3 year old kindergarten children. [METHODS] 427 three year old children were examined in kindergarten with the Retinomax without cycloplegia. A gold standard was established in all children by two orthoptic exam... | null | 1.26 | 185 | Ophthalmology; Sensory Systems; Cellular and Molecular Neuroscience | Medicine; Neuroscience | 2,001 |
11,565,873 | Possible control of intermittent cerebral ischemia by monitoring of direct-current potentials. | Journal of neurosurgery | J Neurosurg | 95 | 3 | 10.3171/jns.2001.95.3.0495 | eng | 2,001 | 9 | null | null | null | null | [OBJECT] Neurosurgically induced temporary occlusion of intracranial arteries carries the risk of cerebral ischemic damage. Because negative shifts in the cortical direct-current (DC) potential indicate tissue depolarization and, thus, critical ischemic stress, the authors hypothesized that recordings of these potentia... | null | 1.482 | 244 | Neurology; Surgery | Medicine | 2,001 |
11,565,728 | Multicenter experience with the remote access perfusion (RAP) catheter. | The Annals of thoracic surgery | Ann Thorac Surg | 72 | 3 | 10.1016/s0003-4975(01)02951-4 | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] Cardiac operation has rapidly evolved toward less invasive procedures. Total body perfusion from femoral or iliac vessels combined with endovascular aortic clamping can be achieved using the remote access perfusion (RAP) catheter without opening the sternum. The results of all reported RAP procedures were ... | null | 1.484 | 230 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,001 |
11,565,402 | Low-amplitude, extremely low frequency magnetic fields for the treatment of osteoarthritic knees: a double-blind clinical study. | Alternative therapies in health and medicine | Altern Ther Health Med | 7 | 5 | null | eng | 2,001 | null | null | null | null | null | [CONTEXT] Noninvasive magnetotherapeutic approaches to bone healing have been successful in past clinical studies. [OBJECTIVE] To determine the effectiveness of low-amplitude, extremely low frequency magnetic fields on patients with knee pain due to osteoarthritis. [DESIGN] Placebo-controlled, randomized, double-blind ... | null | 0.315 | 78 | Complementary and Alternative Medicine; Medicine | Medicine | 2,001 |
11,564,590 | Is the recommendation for pneumococcal vaccination of HIV patients evidence based? | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology | J Clin Virol | 22 | 3 | 10.1016/s1386-6532(01)00197-4 | eng | 2,001 | 10 | null | null | null | null | [BACKGROUND] both the current NHMRC guidelines of Australia and the USPHS/IDSA guidelines recommend pneumococcal vaccine be given to all patients with HIV infection despite a paucity of data to support these recommendations. [OBJECTIVES] the aim of this study was to assess the incidence of invasive pneumococcal disease... | null | 0.715 | 129 | Infectious Diseases; Virology | Immunology and Microbiology; Medicine | 2,001 |
11,563,936 | Immunohistochemical detection of atrial natriuretic factor (ANF) in different ovarian cell types. | Endocrine regulations | Endocr Regul | 35 | 2 | null | eng | 2,001 | 6 | null | null | null | null | [OBJECTIVE] Atrial natriuretic factor (ANF) and its receptors were identified in various tissues and organs including the female reproductive system. The present studies were undertaken to investigate ANF localization in immature rat ovaries, and the changes of ANF expression in response to different ovarian hormonal c... | null | null | null | null | null | null |
11,563,605 | Haemoglobin adducts from aromatic amines in children in relation to area of residence and exposure to environmental tobacco smoke. | International archives of occupational and environmental health | Int Arch Occup Environ Health | 74 | 6 | 10.1007/s004200100243 | eng | 2,001 | 8 | null | null | null | null | [OBJECTIVE] The influence of area of residence on haemoglobin (Hb) adducts of 4-aminobiphenyl (4-ABP), o-, m-, p-toluidine and o-anisidine was investigated in children from three different-sized Bavarian cities - Munich, Augsburg and Eichstätt, with 1,300,000, 250,000 and 13,000 inhabitants, respectively--and was compa... | null | 0.492 | 105 | Public Health, Environmental and Occupational Health | Medicine | 2,001 |
11,562,651 | Expectations of chiropractic patients: the construction of a questionnaire. | Journal of manipulative and physiological therapeutics | J Manipulative Physiol Ther | 24 | 7 | null | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] Because chiropractic has increasingly been incorporated into the National Health Services and insurance company policies, it is important to evaluate treatment outcome and patient satisfaction. There are conflicting views about whether expectation plays a role in patient satisfaction. [OBJECTIVE] To design... | null | 0.392 | 87 | Chiropractics | Health Professions | 2,001 |
11,562,613 | A modified technique for measurement of nasal transepithelial potential difference in infants. | The Journal of pediatrics | J Pediatr | 139 | 3 | 10.1067/mpd.2001.116278 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To establish a method for measuring nasal transepithelial potential difference (PD) in infants. [STUDY DESIGN] A modified infant method (smaller catheter size, reduced flow rates, and shorter protocol time) was compared with an established adult nasal PD method in 10 adult volunteers (4 with cystic fibrosis... | null | 1.633 | 246 | Pediatrics, Perinatology and Child Health | Medicine | 2,001 |
11,562,393 | Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk. | Journal of the National Cancer Institute | J Natl Cancer Inst | 93 | 18 | 10.1093/jnci/93.18.1411 | eng | 2,001 | 9 | 19 | null | null | null | [BACKGROUND] UDP-glucuronosyltransferase 1A7 (UGT1A7) detoxifies several tobacco carcinogens. We determined whether UGT1A7 expression is observed in normal orolaryngeal tissue and whether UGT1A7 allelic variations are associated with the risk for orolaryngeal cancer. [METHODS] UGT1A7 expression in normal orolaryngeal t... | null | 3.925 | 394 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,561,827 | Second trimester pregnancy termination: a comparison of 600 and 800 micrograms of intravaginal misoprostol. | The journal of obstetrics and gynaecology research | J Obstet Gynaecol Res | 27 | 3 | 10.1111/j.1447-0756.2001.tb01235.x | eng | 2,001 | 6 | null | null | null | null | [OBJECTIVE] To compare the effectiveness of 600 and 800 microg of misoprostol administered intravaginally every 12 hours for termination of second trimester pregnancies. [METHODS] One hundred and forty-three pregnant women at 14-26 weeks' gestation were randomized in 2 groups to receive either 600 microg (N = 67), or 8... | null | 0.264 | 68 | Medicine; Obstetrics and Gynecology | Medicine | 2,001 |
11,561,262 | Effect of impulse duration on patients' perception of electrical stimulation and block effectiveness during axillary block in unsedated ambulatory patients. | Regional anesthesia and pain medicine | Reg Anesth Pain Med | 26 | 5 | 10.1053/rapm.2001.26217 | eng | 2,001 | null | null | null | null | null | [BACKGROUND AND OBJECTIVES] Chronaxie of the motor-neurons (A-alpha) is shorter than that of the sensory A-delta and C neurons. Therefore, a short current impulse should elicit a painless muscle twitch. This randomized, double-blind study of patients having ambulatory axillary block by multiple neurostimulations compar... | null | 0.701 | 130 | Anesthesiology and Pain Medicine; Medicine | Medicine | 2,001 |
11,561,223 | Chronic heart failure in the community: missed diagnosis and missed opportunities. | Journal of cardiac failure | J Card Fail | 7 | 3 | 10.1054/jcaf.2001.26905 | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] The aim of this study was to determine the incidence of congestive heart failure (CHF) in patients discharged from a hospital without a diagnosis of CHF who were admitted with shortness of breath and had a low left ventricular ejection fraction (LVEF). CHF is a devastating disease in terms of financial cos... | null | 1.14 | 127 | Cardiology and Cardiovascular Medicine | Medicine | 2,001 |
11,560,271 | Training failure among yearling horses. | American journal of veterinary research | Am J Vet Res | 62 | 9 | 10.2460/ajvr.2001.62.1418 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To compare financial returns between pinhooked yearling horses (ie, bought and trained for approximately 5 months with the goal of selling the horse at "2-year-olds in training" sales) that had mild or severe training failure and horses that had planned versus nonplanned training failure. [ANIMALS] 40 Thoro... | null | 0.677 | 105 | Medicine; Veterinary | Medicine; Veterinary | 2,001 |
11,558,811 | Giant vacuole survival time and implications for aqueous humor outflow. | Journal of glaucoma | J Glaucoma | 10 | 4 | 10.1097/00061198-200108000-00006 | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] A quantitative study was conducted to estimate the survival time of giant vacuoles of the endothelial wall of Schlemm's canal once perfusion pressure has dropped to zero. Vacuoles are known to be sensitive to intraocular pressure and could serve as real-time markers of aqueous pressure in the juxtacanalicular... | null | 1.165 | 105 | Ophthalmology | Medicine | 2,001 |
11,558,214 | Ectopic pregnancies: a three year study. | JPMA. The Journal of the Pakistan Medical Association | J Pak Med Assoc | 51 | 7 | null | eng | 2,001 | 7 | null | null | null | null | [OBJECTIVE] To analyze the risk factors and assess the results of management with respect to maternal morbidity and mortality of ectopic pregnancy during the last three years. [SETTING] Ziauddin Medical University Hospital, North Nazimabad campus (ZMUH), Karachi. [RESULTS] Forty-three patients were admitted with ectopi... | null | null | null | null | null | null |
11,557,704 | Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomised, parallel group, double blind, placebo controlled trial. | BMJ (Clinical research ed.) | BMJ | 323 | 7313 | 10.1136/bmj.323.7313.596 | eng | 2,001 | 9 | 15 | null | null | null | [OBJECTIVES] To evaluate the safety and efficacy of botulinum toxin type A in the treatment of bilateral primary axillary hyperhidrosis. [DESIGN] Multicentre, randomised, parallel group, placebo controlled trial. [SETTING] 17 dermatology and neurology clinics in Belgium, Germany, Switzerland, and the United Kingdom. [P... | null | 1.152 | 519 | Medicine | Medicine | 2,001 |
11,556,935 | Efficacy of patient letter reminders on cervical cancer screening: a meta-analysis. | Journal of general internal medicine | J Gen Intern Med | 16 | 8 | 10.1046/j.1525-1497.2001.016008567.x | eng | 2,001 | 8 | null | null | null | null | [OBJECTIVE] To perform a meta-analysis on existing randomized controlled trials to investigate the efficacy of patient letter reminders on increasing cervical cancer screening using Pap smears. [METHODS] A search was conducted for all relevant published and unpublished studies between the years 1966 and 2000. Eligibili... | null | 1.454 | 224 | Internal Medicine | Medicine | 2,001 |
11,555,441 | Risk factors for hepatitis C virus infection in male adults in Rawalpindi-Islamabad, Pakistan. | Tropical medicine & international health : TM & IH | Trop Med Int Health | 6 | 9 | 10.1046/j.1365-3156.2001.00779.x | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To identify risk factors associated with HCV infection in Islamabad-Rawalpindi. [METHODS] Fifty-seven cases and 180 controls were enrolled from various departments of the nine major hospitals of the Rawalpindi-Islamabad during July-September 1998. Cases were enzyme-linked immunosorbent assay (ELISA) positiv... | null | null | null | null | null | null |
11,555,124 | Screening for thyroid disease of 15-17-year-old schoolchildren in an area with normal iodine intake. | Journal of internal medicine | J Intern Med | 250 | 3 | 10.1046/j.1365-2796.2001.00878.x | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] The prevalence of thyroid disease in Swedish schoolchildren is today insufficiently known. The aim of the study was therefore to determine the prevalence of abnormal thyroid function and thyroid autoimmunity in teen-age schoolchildren and to compare the findings with a healthy control group of 60-65-year-ol... | null | 1.181 | 195 | Internal Medicine | Medicine | 2,001 |
11,554,691 | During pregnancy, in the context of a Th2-type cytokine profile, serum IL-6 levels might condition the quality of the synthesized antibodies. | American journal of reproductive immunology (New York, N.Y. : 1989) | Am J Reprod Immunol | 46 | 3 | 10.1034/j.1600-0897.2001.d01-1.x | eng | 2,001 | 9 | null | null | null | null | [PROBLEM] In recent years, the central role of cytokines in the immune response has been widely studied. It is considered that a T helper (Th)1-type cytokine profile is associated with the rejection phenomenon, whereas a Th2-type cytokine profile is associated with immunological tolerance. In pregnancy, the enhanced Th... | null | 0.815 | 119 | Obstetrics and Gynecology; Reproductive Medicine; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,001 |
11,553,900 | Laser resurfacing with a long pulse erbium:YAG laser compared to the 950 ms pulsed CO(2) laser. | Lasers in surgery and medicine | Lasers Surg Med | 29 | 2 | 10.1002/lsm.1099 | eng | 2,001 | null | null | null | null | null | [BACKGROUND AND OBJECTIVE] Laser resurfacing with the 950 micros pulsed CO(2) laser is an effective treatment for photodamage and acne scarring; however, the potential for prolonged erythema and delayed re-epithelialization dissuade many patients from the procedure. With the use of erbium lasers alone, there is a decre... | null | 0.748 | 130 | Dermatology; Surgery | Medicine | 2,001 |
11,553,898 | Identification of cervical intraepithelial neoplasia (CIN) using UV-excited fluorescence and diffuse-reflectance tissue spectroscopy. | Lasers in surgery and medicine | Lasers Surg Med | 29 | 2 | 10.1002/lsm.1097 | eng | 2,001 | null | null | null | null | null | [BACKGROUND AND OBJECTIVE] The diagnostic potentials of ultraviolet-excitation fluorescence spectroscopy and diffuse-reflectance spectroscopy of tissue are assessed in a study to identify cervical intraepithelial neoplasia (CIN) in vivo. A multivariate algorithm is used to classify tissue into normal tissues, CIN I, an... | null | 0.748 | 130 | Dermatology; Surgery | Medicine | 2,001 |
11,553,201 | The hospital and home use of a 30-second hand-held blood ketone meter: guidelines for clinical practice. | Diabetic medicine : a journal of the British Diabetic Association | Diabet Med | 18 | 8 | 10.1046/j.1464-5491.2001.00550.x | eng | 2,001 | 8 | null | null | null | null | [AIMS] To establish the role of the measurement of beta-hydroxybutyrate (beta-OHB) in distinguishing simple hyperglycaemia from ketosis, and as an indicator of adequate resolution of ketoacidosis, using an electrochemical blood ketone meter. The aim of the study is to assess the accuracy and precision of the meter and ... | null | 1.302 | 171 | Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,553,108 | Association of caries experience in 12-year-old children in Heidelberg, Germany, and Montpellier, France, with different caries preventive measures. | Community dentistry and oral epidemiology | Community Dent Oral Epidemiol | 29 | 5 | 10.1034/j.1600-0528.2001.290505.x | eng | 2,001 | 10 | null | null | null | null | [UNLABELLED] In Germany and France, different approaches to oral health promotion have been chosen. [OBJECTIVES] It was the aim of the present study to assess whether different preventive measures were positively or negatively associated with caries experience in 12-year-old children in Heidelberg, Germany, and in Mont... | null | 0.894 | 118 | Dentistry; Public Health, Environmental and Occupational Health | Dentistry; Medicine | 2,001 |
11,552,967 | Waiting for something to happen: hospitalization with placenta previa. | Birth (Berkeley, Calif.) | Birth | 28 | 3 | 10.1046/j.1523-536x.2001.00186.x | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] Placenta previa occurs in approximately 1 of every 200 pregnancies. No research examining women's experiences of this condition has been published. The objective of this study was to describe the experience of women hospitalized with placenta previa. [METHODS] A descriptive study was conducted using a conv... | null | 1.161 | 96 | Obstetrics and Gynecology | Medicine | 2,001 |
11,552,170 | Shear bond strength of resin composite veneering material to gold alloy with varying metal surface preparations. | The Journal of prosthetic dentistry | J Prosthet Dent | 86 | 3 | 10.1067/mpr.2001.114823 | eng | 2,001 | 9 | null | null | null | null | [STATEMENT OF PROBLEM] Although adequate surface preparation is indispensable to achieve a consistent and durable bond between resin composite materials and the metal substructures of veneered restorations, information on the bonding performance of current metal adhesive systems is limited. [PURPOSE] The purpose of thi... | null | 0.527 | 160 | Medicine; Oral Surgery | Dentistry; Medicine | 2,001 |
11,552,075 | Evaluation of a concurrent multicomponent collection system for the collection and storage of WBC-reduced RBC apheresis concentrates. | Transfusion | Transfusion | 41 | 9 | 10.1046/j.1537-2995.2001.41091159.x | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] Multicomponent apheresis procedures offer the possibility of collecting blood components that are standardized, as compared to those available with whole-blood donations. A new separator program for the concurrent collection of RBCs, platelets, and plasma (Amicus, Baxter Healthcare) was evaluated. [STUDY D... | null | 1.038 | 153 | Hematology; Immunology and Allergy; Immunology | Immunology and Microbiology; Medicine | 2,001 |
11,550,143 | Lymphedema after sentinel lymphadenectomy for breast carcinoma. | Cancer | Cancer | 92 | 4 | 10.1002/1097-0142(20010815)92:4<748::aid-cncr1378>3.0.co;2-v | eng | 2,001 | 8 | 15 | null | null | null | [BACKGROUND] Initial studies of sentinel lymphadenectomy for patients with breast carcinoma confirmed that the status of the sentinel lymph nodes was an accurate predictor of the presence of metastatic disease in the axillary lymph nodes. Sentinel lymphadenectomy, as an axillary staging procedure, has risks of morbidit... | null | 1.593 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,549,873 | Clinical and endocrine characteristics in atypical and classical growth hormone insensitivity syndrome. | Hormone research | Horm Res | 55 | 3 | 10.1159/000049983 | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] Classical growth hormone insensitivity syndrome (GHIS) comprises a dysmorphic phenotype, extreme short stature (height SDS < 3), normal GH and low IGF-I and IGFBP-3. Wide clinical variation is recognised with classical and atypical forms. We aimed to delineate features of the milder "atypical" GHIS phenotyp... | null | null | null | null | null | null |
11,549,851 | Different effects of cyclosporine a and FK506 on potassium transport systems in MDCK cells. | Experimental nephrology | Exp Nephrol | 9 | 5 | 10.1159/000052629 | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Hyperkalemia and metabolic acidosis are common manifestations in patients receiving the immunosuppressive agent cyclosporine A (CsA) and the recently introduced FK506. We compared the acute toxic and antiproliferative effects as well as the effects on the transport activity of Na(+)/K(+)-ATPase and Na(+)/K... | null | null | null | null | null | null |
11,549,381 | Seizures induce phase shifts of rat circadian rhythms. | Brain research | Brain Res | 913 | 2 | 10.1016/s0006-8993(01)02780-9 | eng | 2,001 | 9 | 21 | null | null | null | [RATIONALE] Epileptic seizures may alter neuroendocrinological cycles. Light pulses induce phase shifts in circadian rhythms. Using hippocampal-kindled rats to ensure maximal clinical expression, we determined if seizures likewise induce phase shifts. [METHODS] We monitored the circadian rhythm of temperature (CRT) wit... | null | 1.241 | 262 | Neurology; Neuroscience; Developmental Biology; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | 2,001 |
11,548,564 | Comparison of outcome predictions made by physicians, by nurses, and by using the Mortality Prediction Model. | American journal of critical care : an official publication, American Association of Critical-Care Nurses | Am J Crit Care | 10 | 5 | null | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] Critical care nurses must collaborate with physicians, patients, and patients' families when making decisions about aggressiveness of care. However, few studies address nurses' ability to predict outcomes. [OBJECTIVES] To compare predictions of survival outcomes made by nurses, by physicians, and by using ... | null | 0.575 | 95 | Critical Care Nursing; Medicine | Medicine; Nursing | 2,001 |
11,547,650 | Maternal mean arterial pressure and oral glucose tolerance test results. Relationship in normotensive women. | The Journal of reproductive medicine | J Reprod Med | 46 | 8 | null | eng | 2,001 | 8 | null | null | null | null | [OBJECTIVE] To examine the relationship between oral glucose tolerance test (OGTT) results and maternal mean arterial pressure (MAP) throughout pregnancy in normotensive women. [STUDY DESIGN] A retrospective study was performed on 84 pregnant women with normal and abnormal antenatal OGTT results who delivered in a 12-m... | null | null | null | null | null | null |
11,547,302 | Is profound hypothermia required for storage of cardiac allografts? | The Journal of thoracic and cardiovascular surgery | J Thorac Cardiovasc Surg | 122 | 3 | 10.1067/mtc.2001.115918 | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] Improved methods of cardiac allograft protection are required to expand the pool of potentially available organs and to enhance the recovery of grafts subjected to prolonged ischemia. We have previously demonstrated that limited coronary perfusion provided by donor blood harvested at the time of organ proc... | null | 2.205 | 225 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,001 |
11,547,295 | Superior cavopulmonary anastomosis suppresses the activity and expression of pulmonary angiotensin-converting enzyme. | The Journal of thoracic and cardiovascular surgery | J Thorac Cardiovasc Surg | 122 | 3 | 10.1067/mtc.2001.115698 | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND] Superior cavopulmonary anastomosis is widely used for palliation of various forms of univentricular heart defects. However, clinically significant pulmonary arteriovenous malformations develop in 15% to 25% of patients after surgery. [OBJECTIVE] To assess altered regulation of pulmonary vascular tone cause... | null | 2.205 | 225 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,001 |
11,547,107 | Changing concepts concerning the management of vesicoureteral reflux. | The Journal of urology | J Urol | 166 | 4 | null | eng | 2,001 | 10 | null | null | null | null | [PURPOSE] Conservative estimates indicate that up to 54% of patients who present with vesicoureteral reflux have dysfunction voiding. Children with voiding dysfunction and vesicoureteral reflux historically have a high breakthrough infection rate of 34% to 43%. Breakthrough infection represents significant morbidity an... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,547,105 | Tunica vaginalis for correcting penile chordee in a rabbit model: is there a difference in flap versus graft? | The Journal of urology | J Urol | 166 | 4 | null | eng | 2,001 | 10 | null | null | null | null | [PURPOSE] We compared tunica vaginalis applied as a flap versus a graft for covering defects in the ventral tunica albuginea in a rabbit model. [MATERIALS AND METHODS] We used 18 New Zealand White rabbits in the study. The urethra was mobilized off of the corpus cavernosum. A defect was created in the ventral aspect of... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,547,102 | Avoidance of inguinal incision in laparoscopically confirmed vanishing testis syndrome. | The Journal of urology | J Urol | 166 | 4 | 10.1097/00005392-200110000-00060 | eng | 2,001 | 10 | null | null | null | null | [PURPOSE] Nonpalpable testicles may be due to the vanishing testis syndrome, intra-abdominal position, examination obscured by obesity or scar tissue and rarely testicular agenesis. Laparoscopy is an excellent means of distinguishing these entities without the need for open abdominal exploration. We investigated whethe... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,547,060 | Phase i study of intravesical vaccinia virus as a vector for gene therapy of bladder cancer. | The Journal of urology | J Urol | 166 | 4 | null | eng | 2,001 | 10 | null | null | null | null | [PURPOSE] Vaccinia virus is a DNA poxvirus previously used as a vaccine to eradicate smallpox. The virus has a high efficiency of infection, replicates in the cytoplasm without chromosomal integration and can transport a large amount of recombinant DNA without losing infectivity. Therefore, it is an excellent choice as... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,701,071 | Alar setback technique: a controlled method of nasal tip deprojection. | Archives of otolaryngology--head & neck surgery | Arch Otolaryngol Head Neck Surg | 127 | 11 | 10.1001/archotol.127.11.1341 | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVES] To describe an alar cartilage-modifying technique aimed at decreasing nasal tip projection in cases with overdeveloped alar cartilages and to compare it with other deprojection techniques used to correct such deformity. [DESIGN] Selected case series. [SETTINGS] University and private practice settings in A... | null | null | null | null | null | null |
11,695,935 | Effects of 2 inhaled corticosteroids on growth: results of a randomized controlled trial. | Archives of pediatrics & adolescent medicine | Arch Pediatr Adolesc Med | 155 | 11 | 10.1001/archpedi.155.11.1248 | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVE] To compare the long-term effect of treatment with fluticasone propionate or beclomethasone dipropionate on growth in asthmatic children. [DESIGN] Prospective, multicenter, randomized, double-blind, parallel-group study. [SETTING] Children requiring regular treatment with inhaled corticosteroids and with a s... | null | null | null | null | null | null |
11,718,704 | Automated detection of the G20210A prothrombin mutation using the LCx microparticle enzyme immunoassay. | Clinica chimica acta; international journal of clinical chemistry | Clin Chim Acta | 314 | 1-2 | 10.1016/s0009-8981(01)00655-6 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] The prothrombin mutation, a G/A transition at position 20210 in the 3' untranslated region of the prothrombin gene, is associated with an increased risk of deep venous thrombosis and obstetrical complications. Several methods have been developed to detect the mutation; however, given the increased demand f... | null | null | null | null | null | null |
11,718,258 | A phase II trial of temozolomide for patients with recurrent or progressive brain metastases. | Journal of neuro-oncology | J Neurooncol | 53 | 3 | 10.1023/a:1012226718323 | eng | 2,001 | 7 | null | null | null | null | [BACKGROUND] Treatment options for patients with recurrent brain metastases are extremely limited. This study was designed to determine the safety and efficacy of temozolomide in the treatment of recurrent or progressive brain metastases. [PATIENTS AND METHODS] Forty-one patients (11 men, 30 women) with a median KPS of... | null | 0.574 | 141 | Cancer Research; Neurology; Neurology; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | 2,001 |
11,717,613 | Usefulness of peak mitral inflow velocity to predict severe mitral regurgitation in patients with normal or impaired left ventricular systolic function. | American heart journal | Am Heart J | 142 | 6 | 10.1067/mhj.2001.118465 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] The aim of this study was to evaluate the reliability of peak mitral inflow (E-wave) velocity, which was thought to be easier and more practical than qualitative and quantitative methods used to grade mitral regurgitation (MR) in patients both with normal and low left ventricular (LV) ejection fraction (EF... | null | 1.574 | 211 | Cardiology and Cardiovascular Medicine | Medicine | 2,001 |
11,716,784 | The functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibition. | BMC developmental biology | BMC Dev Biol | 1 | null | 10.1186/1471-213x-1-15 | eng | 2,001 | null | null | 2,001 | 10 | 25 | [BACKGROUND] The proper balance between epithelial cell proliferation, quiescence, and apoptosis during development is mediated by the specific temporal and spatial appearance of transcription factors, growth factors, cytokines, caspases, etc. Since our prior studies suggest the importance of transcription factor NF-ka... | null | null | null | null | null | null |
11,716,668 | Pediatric residency training on tobacco: training director tobacco survey. | Preventive medicine | Prev Med | 33 | 6 | 10.1006/pmed.2001.0946 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Statements from the American Academy of Pediatrics encourage pediatricians to address tobacco. However, most fail to do so and little is known about the preparation to intervene on tobacco they receive during residency training. [METHODS] The Pediatric Residency Training Director Tobacco Survey was mailed ... | null | 1.051 | 199 | Public Health, Environmental and Occupational Health; Epidemiology | Medicine | 2,001 |
11,714,554 | Even a thin layer of soft tissue may compromise the primary stability of cementless hip stems. | Clinical biomechanics (Bristol, Avon) | Clin Biomech (Bristol) | 16 | 9 | 10.1016/s0268-0033(01)00052-3 | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVE] Aim of the present study is to quantify the minimum thickness of mechanically non-bearing regions around a cementless prosthesis necessary to loose the implant enough to activate interface tissue differentiation. [DESIGN] A finite element model was used to predict the bone-implant micromotion induced by sta... | null | null | null | null | null | null |
11,714,129 | Left ventricular geometry and operative mortality in patients undergoing mitral valve replacement. | Clinical cardiology | Clin Cardiol | 24 | 11 | 10.1002/clc.4960241106 | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] Distortion of left ventricular (LV) shape is often associated with LV dysfunction and is thought to be an independent predictor of survival in patients with coronary disease. [HYPOTHESIS] The purpose of this study was to examine the relationship between LV geometry and hospital mortality in patients with m... | null | 0.622 | 89 | Medicine; Cardiology and Cardiovascular Medicine | Medicine | 2,001 |
11,713,722 | Radiotherapy alone for clinical T4 skin carcinoma of the head and neck with surgery reserved for salvage. | American journal of otolaryngology | Am J Otolaryngol | 22 | 6 | 10.1053/ajot.2001.28083 | eng | 2,001 | null | null | null | null | null | [PURPOSE] To evaluate the outcomes of definitive radiotherapy in the treatment of clinical stage T4 cutaneous carcinomas of the head and neck. [PATIENTS AND METHODS] Between October 1964 and September 1997, 85 patients with 88 biopsy-proven clinical AJCC stage T4 carcinomas of the skin of the head and neck received rad... | null | null | null | null | null | null |
11,713,397 | Effect of intravesical instillations on the human complement factor H related protein (BTA stat) test. | European urology | Eur Urol | 40 | 4 | 10.1159/000049810 | eng | 2,001 | 10 | null | null | null | null | [OBJECTIVES] The BTA stat is a rapid, non-invasive, qualitative urine test that detects bladder tumor-associated antigen (human complement factor H related protein) in urine. The sensitivity of this test is superior to that of urine cytology in detecting primary and recurrent tumors of the urinary bladder. Intravesical... | null | 1.106 | 274 | Urology | Medicine | 2,001 |
11,713,369 | The impact of whole genome sequence data on drug discovery--a malaria case study. | Molecular medicine (Cambridge, Mass.) | Mol Med | 7 | 10 | null | eng | 2,001 | 10 | null | null | null | null | [BACKGROUND] Identification and validation of a drug discovery target is a prominent step in drug development. In the post-genomic era it is possible to reevaluate the association of a gene with a specific biological function to see if a homologous gene can subsume this role. This concept has special relevance to drug ... | null | 1.744 | 136 | Genetics; Genetics; Molecular Medicine; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,713,148 | A new method for the remote collection of nasal and exhaled nitric oxide. | Chest | Chest | 120 | 5 | 10.1378/chest.120.5.1645 | eng | 2,001 | 11 | null | null | null | null | [STUDY OBJECTIVES] The present study introduces a method that has been developed to improve the remote collection and transportation of gas samples from the nose and lungs. [DESIGN] Assessment of agreement between two methods of clinical measurements. [SETTING] Noninvasive exhaled gas measurement at a respiratory resea... | null | 0.916 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,001 |
11,713,067 | Plasma antioxidant vitamins and carotenoids and age-related cataract. | Ophthalmology | Ophthalmology | 108 | 11 | 10.1016/s0161-6420(01)00833-8 | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVE] To investigate the relationships between plasma concentrations of antioxidant vitamins and carotenoids and nuclear, cortical, and posterior subcapsular cataracts in a group of elderly men and women. [DESIGN] Cross-sectional survey. [PARTICIPANTS] Three hundred seventy-two men and women, aged 66 to 75 years,... | null | 2.409 | 297 | Ophthalmology | Medicine | 2,001 |
11,711,779 | Does the choice of treatment influence survival of patients with small hepatocellular carcinoma in compensated cirrhosis? | European journal of gastroenterology & hepatology | Eur J Gastroenterol Hepatol | 13 | 10 | 10.1097/00042737-200110000-00015 | eng | 2,001 | 10 | null | null | null | null | [OBJECTIVE] Untreated patients with small, single hepatocellular carcinoma (HCC) in compensated cirrhosis are characterized by a relatively good prognosis. [METHODS] We report the findings generated in a retrospective study on a cohort of 186 consecutive patients with small (< 5 cm) HCC in Child A or B cirrhosis, who w... | null | null | null | null | null | null |
11,710,633 | Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts. | Cancer chemotherapy and pharmacology | Cancer Chemother Pharmacol | 48 | 4 | 10.1007/s002800100323 | eng | 2,001 | 10 | null | null | null | null | [BACKGROUND] Epothilone compounds (e.g. epothilones A and B) represent a new structural class of microtubule inhibitors with the remarkable ability to inhibit tumor growth of multidrug-resistant cell lines at low nanomolar or even subnanomolar concentrations. Unfortunately, this therapeutic efficacy has only been achie... | null | 0.713 | 127 | Pharmacology; Pharmacology; Toxicology; Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,001 |
11,710,619 | Histological and magnetic resonance imaging alterations after irradiation of meniscus using Holmium:YAG laser. | Journal of clinical laser medicine & surgery | J Clin Laser Med Surg | 19 | 5 | 10.1089/10445470152611973 | eng | 2,001 | 10 | null | null | null | null | [OBJECTIVE] The authors performed an experimental and a prospective clinical study to evaluate the histological and magnetic resonance imaging (MRI) alterations after irradiation of meniscus using holmium:YAG (Ho:YAG) laser VersaPulse Select 60 watts and InfraTome Delivery Systems 30 degrees Handpiece (spot size at fib... | null | null | null | null | null | null |
11,709,636 | Locating, characterizing and minimizing sources of error for a paper case-based structured oral examination in a multi-campus clerkship. | Advances in health sciences education : theory and practice | Adv Health Sci Educ Theory Pract | 6 | 3 | 10.1023/a:1012674102278 | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] To determine consistency of assessment in a new paper case-based structured oral examination in a multi-community pediatrics clerkship, and to identify correctable problems in the administration of examination and assessment process. [METHOD] Nine paper case-based oral examinations were audio-taped. From au... | null | null | null | null | null | null |
11,709,568 | Prospective study of Helicobacter pylori eradication therapy in stage I(E) high-grade mucosa-associated lymphoid tissue lymphoma of the stomach. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology | J Clin Oncol | 19 | 22 | 10.1200/JCO.2001.19.22.4245 | eng | 2,001 | 11 | 15 | null | null | null | [PURPOSE] High-grade mucosa-associated lymphoid tissue (MALT) lymphomas of the stomach are generally believed to be Helicobacter pylori-independent, autonomously growing tumors. However, anecdotal cases of regression of high-grade lymphomas after the cure of H pylori infection had been described. The present prospectiv... | null | 4.111 | 646 | Cancer Research; Medicine; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,709,514 | Interleukin 16 expression and phenotype of interleukin 16 producing cells in Crohn's disease. | Gut | Gut | 49 | 6 | 10.1136/gut.49.6.795 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] The mechanisms involved in the initiation and maintenance of Crohn's disease are poorly understood. Previous studies have demonstrated an increased number of infiltrating CD4+ T cells within the inflammatory affected bowel wall in Crohn's disease. Novel therapy approaches using anti-CD4 antibodies are thou... | null | 2.014 | 364 | Gastroenterology | Medicine | 2,001 |
11,709,512 | Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses. | Gut | Gut | 49 | 6 | 10.1136/gut.49.6.783 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug. Its efficacy in comparison with standard mesalazine therapy and the optimum dose for maintaining remission of ulcerative colitis are still unclear. [AIMS] To compare the relapse preventing effect and safety profile of two doses of balsa... | null | 2.014 | 364 | Gastroenterology | Medicine | 2,001 |
11,709,458 | Osteonecrosis in patients with systemic lupus erythematosus develops very early after starting high dose corticosteroid treatment. | Annals of the rheumatic diseases | Ann Rheum Dis | 60 | 12 | 10.1136/ard.60.12.1145 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVES] To investigate the actual time of onset of osteonecrosis (ON) after high dose corticosteroid treatment in systemic lupus erythematosus (SLE). [METHODS] 72 patients with active SLE, who received high dose corticosteroid for the first time, for the development of ON at hips and knees were monitored by magnet... | null | 1.054 | 300 | Biochemistry, Genetics and Molecular Biology; Immunology and Allergy; Rheumatology; Immunology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,001 |
11,709,168 | The Ras-Byr2RBD complex: structural basis for Ras effector recognition in yeast. | Structure (London, England : 1993) | Structure | 9 | 11 | 10.1016/s0969-2126(01)00674-8 | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] The small GTP binding protein Ras has important roles in cellular growth and differentiation. Mutant Ras is permanently active and contributes to cancer development. In its activated form, Ras interacts with effector proteins, frequently initiating a kinase cascade. In the lower eukaryotic Schizosaccharomy... | null | null | null | null | null | null |
11,708,995 | Genetic and clinical analysis of spinocerebellar ataxia type 8 repeat expansion in Italy. | Archives of neurology | Arch Neurol | 58 | 11 | 10.1001/archneur.58.11.1856 | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] The spinocerebellar ataxias (SCAs) are clinically heterogeneous disorders caused by triplet repeat expansions in the sequence of specific disease genes. Spinocerebellar ataxia type 8 (SCA8), originally described in a family characterized by pure cerebellar ataxia with slow disease progression, presents wit... | null | null | null | null | null | null |
11,708,685 | Social support and avoidant coping: correlates of depressed mood during pregnancy in minority women. | Women & health | Women Health | 34 | 3 | 10.1300/J013v34n03_02 | eng | 2,001 | null | null | null | null | null | [INTRODUCTION] The purpose of this study was to evaluate several psychosocial correlates of depressed mood during pregnancy. The psychosocial factors examined included background characteristics (socioeconomic status, planning of pregnancy), perceived social support, and coping styles. [METHODS] One hundred fifty pregn... | null | null | null | null | null | null |
11,708,290 | The evaluation of diagnostic accordance between plain radiography and bone scintigraphy for the assessment of sternum and rib fractures in the early period of blunt trauma. | Ulusal travma dergisi = Turkish journal of trauma & emergency surgery : TJTES | Ulus Travma Derg | 7 | 4 | null | eng | 2,001 | 10 | null | null | null | null | [OBJECTIVE] To evaluate the diagnostic accordance between scintigraphy and radiography in the early period following blunt thoracic trauma. [DESIGN] Double-blind, prospective clinical study. [METHODS] Thirty-four adult patients with blunt thoracic trauma were examined by plain radiography and scintigraphy within 24 hou... | null | null | null | null | null | null |
11,707,790 | Epidural fentanyl speeds the onset of sensory block during epidural lidocaine anesthesia. | Regional anesthesia and pain medicine | Reg Anesth Pain Med | 26 | 6 | 10.1053/rapm.2001.27852 | eng | 2,001 | null | null | null | null | null | [BACKGROUND AND OBJECTIVES] Shortening the onset time of sensory block is a practical goal to improve the quality of epidural anesthesia. The addition of fentanyl to a local anesthetic solution is widely used during epidural anesthesia. This randomized double-blind study examined the onset time of sensory block during ... | null | 0.701 | 130 | Anesthesiology and Pain Medicine; Medicine | Medicine | 2,001 |
11,707,714 | The cortical shell architecture of human cervical vertebral bodies. | Spine | Spine (Phila Pa 1976) | 26 | 22 | 10.1097/00007632-200111150-00016 | eng | 2,001 | 11 | 15 | null | null | null | [STUDY DESIGN] An anatomic study of cervical vertebral bodies. [OBJECTIVES] To provide quantitative information on the cortical shell architecture of the middle and lower cervical vertebral bodies. [SUMMARY OF BACKGROUND DATA] Some external dimensions have been measured, but little quantitative data exists for the cort... | null | 1.078 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,001 |
11,707,702 | The relationship between apoptosis of endplate chondrocytes and aging and degeneration of the intervertebral disc. | Spine | Spine (Phila Pa 1976) | 26 | 22 | 10.1097/00007632-200111150-00004 | eng | 2,001 | 11 | 15 | null | null | null | [STUDY DESIGN] Apoptosis in cervical intervertebral disc cells and cartilaginous endplate cells was examined by the nick end labeling (TUNEL) technique during the process of natural aging and in a mouse experimental spondylosis model. [OBJECTIVES] To determine the role of apoptosis in aging and degeneration of interver... | null | 1.078 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,001 |
11,707,675 | Drug use and sexual risk behavior among gay and bisexual men who attend circuit parties: a venue-based comparison. | Journal of acquired immune deficiency syndromes (1999) | J Acquir Immune Defic Syndr | 28 | 4 | 10.1097/00126334-200112010-00011 | eng | 2,001 | 12 | 1 | null | null | null | [CONTEXT] HIV risk behavior among urban gay/bisexual men has recently increased. High-risk sexual activity and drug use may be particularly high during circuit party (CP) weekends, during which gay/bisexual men congregate for social activities and dancing. [OBJECTIVES] To compare prevalence of risk behaviors during CP ... | null | 1.743 | 176 | Infectious Diseases; Pharmacology | Medicine | 2,001 |
11,706,631 | Management of diabetic foot--two years experience. | Journal of Ayub Medical College, Abbottabad : JAMC | J Ayub Med Coll Abbottabad | 13 | 1 | null | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Diabetic foot is a serious complication of diabetes mellitus and may be the initial presentation of undiagnosed diabetes mellitus. A study of 48 patients with diabetic foot admitted in Surgical B Unit of Ayub Teaching Hospital over a period of two years is presented here. [METHODS] This study was done to i... | null | null | null | null | null | null |
11,706,336 | Motor vehicle crash fatalities in the elderly: rural versus urban. | The Journal of trauma | J Trauma | 51 | 5 | 10.1097/00005373-200111000-00011 | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] The elderly contribute disproportionately to hospital trauma mortality and expense. This population and its traffic fatality rate are increasing. The purpose of this study was to determine how the effect of age on vehicle-related mortality is modified by population density. [METHODS] FARS data for vehicle ... | null | null | null | null | null | null |
11,704,777 | A study of the nonprescription drug consumer's understanding of the ranitidine product label and actual product usage patterns in the treatment of episodic heartburn. | American journal of therapeutics | Am J Ther | 8 | 6 | 10.1097/00045391-200111000-00003 | eng | 2,001 | null | null | null | null | null | [INTRODUCTION] A study of the consumer's understanding of the product label instructions and the resulting product use were conducted to support the switch of a product from prescription to nonprescription status. H2 receptor antagonists have recently been approved for nonprescription use. This study evaluated the cons... | null | 0.3 | 71 | Medicine; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,001 |
11,704,520 | A clinical performance exercise for medicine--pediatrics residents emphasizing complex psychosocial skills. | Academic medicine : journal of the Association of American Medical Colleges | Acad Med | 76 | 11 | 10.1097/00001888-200111000-00021 | eng | 2,001 | 11 | null | null | null | null | [PURPOSE] To assess the skills of internal medicine-pediatrics (med-peds) residents in evaluating and counseling patients with complex psychosocial problems using a clinical performance exercise (CPE). [METHOD] The authors designed a 13-station CPE [nine standardized-patient (SP) stations and four non-SP stations]. Eig... | null | 0.681 | 199 | Education; Medicine | Medicine; Social Sciences | 2,001 |
11,704,479 | Anti-proliferative properties of the phosphodiesterase-4 inhibitor rolipram can supplement immunosuppressive effects of cyclosporine for treatment of obliterative bronchiolitis in heterotopic rat allografts. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | J Heart Lung Transplant | 20 | 11 | 10.1016/s1053-2498(01)00340-0 | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] Potent prevention and therapy of obliterative bronchiolitis may enhance long-term survival after lung transplantation. Phosphodiesterase-4 inhibitors have been established for anti-inflammatory treatment, particularly of pulmonary diseases. Using a heterotopic rat model, the effect of rolipram was investig... | null | 1.097 | 162 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery; Transplantation | Medicine | 2,001 |
11,704,178 | Validity of transabdominal sonography in the detection of a two-vessel umbilical cord. | Obstetrics and gynecology | Obstet Gynecol | 98 | 5 Pt 1 | 10.1016/s0029-7844(01)01572-1 | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVE] To determine the validity of transabdominal ultrasound in the detection of a two-vessel and a three-vessel umbilical cord. [METHODS] The ultrasound and pathology databases were collated between January 1, 1999, and December 31, 2000. Only those cases with ultrasound and pathology information concerning the ... | null | 1.316 | 268 | Obstetrics and Gynecology | Medicine | 2,001 |
11,703,614 | Kidney transplantation in patients with IgA mesangial glomerulonephritis. | Kidney international | Kidney Int | 60 | 5 | 10.1046/j.1523-1755.2001.00006.x | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] Strategies for treating IgA glomerulonephritis (IgAGN) are controversial, particularly with regards to the long-term results of kidney transplantation, including the risk of recurrence of IgAGN post-transplant and the impact of this recurrence on graft survival. [METHODS] The outcomes of 106 adults transpl... | null | null | null | null | null | null |
11,703,603 | Angiotensin II enhances tubuloglomerular feedback via luminal AT(1) receptors on the macula densa. | Kidney international | Kidney Int | 60 | 5 | 10.1046/j.1523-1755.2001.00999.x | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] Recent studies have revealed angiotensin II subtype 1 (AT1) receptors on macula densa cells, raising the possibility that angiotensin II (Ang II) could enhance tubuloglomerular feedback (TGF) by affecting macula densa cell function. We hypothesized that Ang II enhances TGF via activation of AT1 receptors o... | null | null | null | null | null | null |
11,703,589 | Dysregulation of LDL receptor under the influence of inflammatory cytokines: a new pathway for foam cell formation. | Kidney international | Kidney Int | 60 | 5 | 10.1046/j.1523-1755.2001.00025.x | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] Lipid-mediated renal injury is an important component of glomerulosclerosis and its similarity to atherosclerosis is well described. This study focused on the relationship between lipid-mediated injury and inflammation by examining the role of inflammatory cytokines in the regulation of human mesangial cel... | null | null | null | null | null | null |
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