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11,767,963 | Surgical antibiotic prophylaxis: effect in postoperative infections. | European journal of epidemiology | Eur J Epidemiol | 17 | 4 | 10.1023/a:1012794330908 | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] to assess the risk of surgical wound infection and hospital acquired infections among patients with and without adequate antibiotic prophylaxis. Also, to provide models to predict the contributing factors of hospital infection and surgical wound infection. [DESIGN] survey study. Prospective cohort study ove... | null | null | null | null | null | null |
11,766,871 | Psychosocial, lifestyle, and health status variables in predicting high attendance among adults. | The British journal of general practice : the journal of the Royal College of General Practitioners | Br J Gen Pract | 51 | 473 | null | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Increasing consultation rates have implications for the organisation of health services, the quality of care, and understanding the decision to consult. Most quantitative studies have concentrated on very high attenders--not those attending five or more times a year, who are responsible for most (60%) cons... | null | 1.116 | 125 | Family Practice; Medicine | Medicine | 2,001 |
11,766,487 | Quality of life among children aged 2-17 years in the five Nordic countries. Comparison between 1984 and 1996. | European journal of public health | Eur J Public Health | 11 | 4 | 10.1093/eurpub/11.4.437 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] The aim of the study was to analyse children's quality of life (QoL) in the five Nordic countries from 1984 to 1996, a period in which major economic recessions occurred. [METHODS] The study design was cross-sectional based on a random sample of 3000 children in each country, aged 2 to 17 years, totalling ... | null | 0.453 | 118 | Public Health, Environmental and Occupational Health | Medicine | 2,001 |
11,766,481 | Impact of private funding on access to elective hospital treatment in the regions of England and Wales. National records survey. | European journal of public health | Eur J Public Health | 11 | 4 | 10.1093/eurpub/11.4.402 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] The UK National Health Service aims to match access to health care to the level of need and to reduce inequalities in the health of sub-populations. One in ten persons have private medical insurance (PMI). This study describes the impact of private purchasing on access to hospital care in regions according... | null | 0.453 | 118 | Public Health, Environmental and Occupational Health | Medicine | 2,001 |
11,765,288 | Major depression and drug disorders in adolescence: general and specific impairments in early adulthood. | Journal of the American Academy of Child and Adolescent Psychiatry | J Am Acad Child Adolesc Psychiatry | 40 | 12 | 10.1097/00004583-200112000-00013 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To identify adulthood impairments associated with major depression and drug disorders in adolescence, distinguishing between general impairments for both disorders and specific impairments for each disorder. [METHOD] Within a longitudinal community study (N= 365), the Diagnostic Interview Schedule provided ... | null | 2.441 | 282 | Developmental and Educational Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,001 |
11,763,183 | In vitro responses of equine colonic arterial and venous rings to adenosine triphosphate. | American journal of veterinary research | Am J Vet Res | 62 | 12 | 10.2460/ajvr.2001.62.1928 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To evaluate the in vitro effects of adenosine tryphosphate (ATP) on vasomotor tone of equine colonic vasculature. [SAMPLE POPULATION] Arteries and veins from the left ventral colon of 14 mixed-breed horses euthanatized for reasons unrelated to cardiovascular or gastrointestinal tract disease. [PROCEDURES] E... | null | 0.677 | 105 | Medicine; Veterinary | Medicine; Veterinary | 2,001 |
11,762,658 | Comparative study of the effects of a progestogen-only pill containing desogestrel and an intrauterine contraceptive device in lactating women. | BJOG : an international journal of obstetrics and gynaecology | BJOG | 108 | 11 | 10.1111/j.1471-0528.2003.00239.x | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVE] To evaluate the effects of desogestrel 75 microg/day, as a progestogen-only pill compared with a copper-bearing intrauterine contraceptive device (IUCD) on lactation and to study the safety of both treatments in mothers and children. Transfer of etonogestrel to breast milk was studied in a subgroup of desog... | null | 1.339 | 195 | Obstetrics and Gynecology | Medicine | 2,001 |
11,762,539 | Spectrum of normal intrauterine cavity sonographic findings after first-trimester abortion. | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | J Ultrasound Med | 20 | 12 | 10.7863/jum.2001.20.12.1277 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To characterize the sonographic appearance of the uterine cavity after uncomplicated first-trimester abortion. [METHODS] Women who underwent uterine evacuation for first-trimester abortion were referred for endovaginal sonographic examination within the week after the procedure. Special attention was direct... | null | 0.601 | 108 | Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,001 |
11,761,634 | Antipsychotic drugs and obesity: is prolactin involved? | Canadian journal of psychiatry. Revue canadienne de psychiatrie | Can J Psychiatry | 46 | 9 | 10.1177/070674370104600906 | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVES] To correlate the anthropometric indexes (Body Mass Index [BMI] and Waist-Hip ratio [WHR]) with the serum prolactin levels in a heterogeneous population of patients treated with typical antipsychotic (AP) drugs. [METHODS] We evaluated BMI, WHR, and fasting serum prolactin of inpatients (n = 105) and outpati... | null | null | null | null | null | null |
11,761,442 | Biodistribution of 111indium-labeled macrophages infused intravenously in patients with renal carcinoma. | Cancer immunology, immunotherapy : CII | Cancer Immunol Immunother | 50 | 9 | 10.1007/s002620100224 | eng | 2,001 | 11 | null | null | null | null | [PURPOSE] We have previously reported a clinical trial on the intravenous injection of autologous activated macrophages (AAM) in 15 patients with renal carcinoma. The present paper concerns scintigraphic investigations performed in 11 of these patients after injection of 111indium oxinate-radiolabeled AAM. [METHODS] AA... | null | 0.988 | 142 | Medicine; Oncology; Cancer Research; Immunology; Immunology and Allergy | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,001 |
11,760,489 | Impact of the Minimum Pricing Policy and introduction of brand (generic) substitution into the Pharmaceutical Benefits Scheme in Australia. | Pharmacoepidemiology and drug safety | Pharmacoepidemiol Drug Saf | 10 | 4 | 10.1002/pds.603 | eng | 2,001 | null | null | null | null | null | [PURPOSE] To describe the effects of introducing the Minimum Pricing Policy (MPP) and generic (brand) substitution in 1990 and 1994 respectively on the dispensing of Pharmaceutical Benefits Scheme (PBS) prescriptions both at the aggregate and individual patient level. [METHODS] The relative proportion of prescriptions ... | null | 0.383 | 113 | Pharmacology; Epidemiology | Medicine | 2,001 |
11,760,104 | Using life expectancy to communicate benefits of health care programs in contingent valuation studies. | Medical decision making : an international journal of the Society for Medical Decision Making | Med Decis Making | 21 | 6 | 10.1177/0272989X0102100605 | eng | 2,001 | null | null | null | null | null | [BACKGROUND] There is growing interest in the use of contingent valuation (CV) to estimate the monetary value of health program benefits. Ideally, CV could be used to value a specific shift in survival curve. However, a shift in survival curve may prove too complex for widespread use in CV instruments. To facilitate th... | null | 1.053 | 124 | Health Policy | Medicine | 2,001 |
11,759,816 | Clinical management of women with genomic BRCA1 and BRCA2 mutations. | Breast cancer research and treatment | Breast Cancer Res Treat | 69 | 2 | 10.1023/a:1012203917104 | eng | 2,001 | 9 | null | null | null | null | [PURPOSE] There is increasing evidence that BRCA1 and BRCA2 associated tumors may differ from sporadic cancers. The purpose of this report is to review the current state of knowledge of BRCA1 and BRCA2, the biology of associated tumors, and possible risk reduction strategies in women with these deleterious mutations. [... | null | 1.307 | 184 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,759,732 | Blood loss in prosthetic hip replacement is not influenced by the AB0 blood group. | The European journal of surgery = Acta chirurgica | Eur J Surg | 167 | 9 | 10.1080/11024150152619264 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To find out if there is a correlation between AB0 type and the amount of blood lost at operation. [DESIGN] Retrospective study. [SETTING] One county and one university hospital, Sweden. [SUBJECTS] 540 patients who underwent primary prosthetic hip replacement under regional anaesthesia. Albumin (n = 298) or ... | null | null | null | null | null | null |
11,758,988 | Confocal microscopic imaging of reticular folds in a laser in situ keratomileusis flap. | Journal of refractive surgery (Thorofare, N.J. : 1995) | J Refract Surg | 17 | 6 | 10.3928/1081-597X-20011101-09 | eng | 2,001 | null | null | null | null | null | [PURPOSE] To report the clinical and confocal microscopic characteristics of reticular folds (mudcracks) in a cornea after laser in situ keratomileusis (LASIK). [METHODS] A 30-year-old male showed reticular flap folds on slit-lamp examination 1 week after LASIK. In addition to slit-lamp biomicroscopy, confocal in vivo ... | null | 1.897 | 113 | Ophthalmology; Surgery | Medicine | 2,001 |
11,758,300 | Pharmacoeconomic component of a clinical trial conducted in Latin America. Conceptual and empirical considerations. | International journal of technology assessment in health care | Int J Technol Assess Health Care | 17 | 4 | null | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Although pharmacoeconomic studies constitute a valuable tool for better managing drug consumption, the conditions under which such studies would be performed in Latin American countries have not been explored. [OBJECTIVES] The aim of this paper is to evaluate the potential advantages of and pitfalls in doi... | null | 0.495 | 79 | Health Policy | Medicine | 2,001 |
11,757,505 | Decreased rate of coronary restenosis after lowering of plasma homocysteine levels. | The New England journal of medicine | N Engl J Med | 345 | 22 | 10.1056/NEJMoa011364 | eng | 2,001 | 11 | 29 | null | null | null | [BACKGROUND] We have previously demonstrated an association between elevated total plasma homocysteine levels and restenosis after percutaneous coronary angioplasty. We designed this study to evaluate the effect of lowering plasma homocysteine levels on restenosis after coronary angioplasty. [METHODS] A combination of ... | null | 8.571 | 1,231 | Medicine | Medicine | 2,001 |
11,756,882 | Comparison of foveal thickness measured with the retinal thickness analyzer and optical coherence tomography. | Retina (Philadelphia, Pa.) | Retina | 21 | 6 | 10.1097/00006982-200112000-00006 | eng | 2,001 | null | null | null | null | null | [PURPOSE] To assess and compare the reliability and reproducibility of retinal thickness measurements for the retinal thickness analyzer (RTA) and optical coherence tomography (OCT) in normal and edematous retina. [METHODS] The authors measured the foveal thickness of 21 normal eyes and 9 eyes with macular edema with b... | null | 0.754 | 149 | Medicine; Ophthalmology | Medicine | 2,001 |
11,756,708 | Hepatocellular carcinoma: detection with gadolinium- and ferumoxides-enhanced MR imaging of the liver. | Radiology | Radiology | 222 | 1 | 10.1148/radiol.2221001599 | eng | 2,002 | 1 | null | null | null | null | [PURPOSE] To test the hypothesis that the accuracy of gadolinium- and ferumoxides-enhanced magnetic resonance (MR) imaging is different in small ( or =1.5-cm) and large (1.5-cm) hepatocellular carcinomas (HCCs). [MATERIALS AND METHODS] Forty-three consecutive patients with chronic liver disease were enrolled in this st... | null | 2.476 | 346 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
11,756,529 | Minimum detectable defect thickness in SPECT myocardial perfusion test: phantom study with (99m)Tc and (201)Tl. | Journal of nuclear medicine technology | J Nucl Med Technol | 29 | 4 | null | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] The purpose of this study was to determine experimentally the minimum thickness (D(min)) of a defect inserted on the myocardial wall of a cardiac phantom at different locations that could be clearly detected in a SPECT perfusion study using (99m)Tc and (201)Tl. [METHODS] Rectangular (or cylindrical) defects... | null | 0.217 | 49 | Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,001 |
11,756,391 | Interleukin-2 receptor concentrations in pregnant women with a history of recurrent miscarriage. | Human reproduction (Oxford, England) | Hum Reprod | 17 | 1 | 10.1093/humrep/17.1.219 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] The mechanism by which the maternal immune system tolerates the fetus during pregnancy is unclear. [METHODS] This study measured interleukin-2 receptor (IL-2R) concentrations in the serum of non-pregnant women (Group 1); healthy first trimester pregnant women (Group 2); pregnant women with a history of rec... | null | 1.501 | 264 | Obstetrics and Gynecology; Rehabilitation; Reproductive Medicine | Medicine | 2,002 |
11,756,370 | Multivariate Markov chain analysis of the probability of pregnancy in infertile couples undergoing assisted reproduction. | Human reproduction (Oxford, England) | Hum Reprod | 17 | 1 | 10.1093/humrep/17.1.103 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Estimating the probability of pregnancy leading to delivery and the influence of clinical factors on that probability is of fundamental importance in the treatment counselling of infertile couples. A variety of statistical techniques have been used to analyse fertility data, many borrowed from survival ana... | null | 1.501 | 264 | Obstetrics and Gynecology; Rehabilitation; Reproductive Medicine | Medicine | 2,002 |
11,756,364 | IL-1, IL-6 and TNF-alpha concentrations in the peritoneal fluid of women with pelvic adhesions. | Human reproduction (Oxford, England) | Hum Reprod | 17 | 1 | 10.1093/humrep/17.1.69 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Pelvic adhesions are a significant cause of morbidity and are associated with infertility and pain. The three pro-inflammatory cytokines interleukin (IL)-1, IL-6 and tumour necrosis factor (TNF)-alpha are involved in adhesion formation/reformation. [METHODS] The concentration of these three cytokines was e... | null | 1.501 | 264 | Obstetrics and Gynecology; Rehabilitation; Reproductive Medicine | Medicine | 2,002 |
11,756,063 | An increase in dietary carotenoids when consuming plant sterols or stanols is effective in maintaining plasma carotenoid concentrations. | The American journal of clinical nutrition | Am J Clin Nutr | 75 | 1 | 10.1093/ajcn/75.1.79 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Plant-sterol-enriched spreads lower LDL cholesterol but may also lower lipid-standardized carotenoids. [OBJECTIVE] Our objective was to assess whether advice to consume specific daily amounts of foods high in carotenoids prevents a reduction in plasma carotenoid concentrations in subjects who consume plant... | null | 2.633 | 390 | Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,002 |
11,756,058 | Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: the Framingham Study. | The American journal of clinical nutrition | Am J Clin Nutr | 75 | 1 | 10.1093/ajcn/75.1.38 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] A common G-to-A substitution in the promoter area (-75 base pairs) of the apolipoprotein A-I gene (APOA1) has been described. The A allele was shown to be associated with higher HDL-cholesterol concentrations in some studies but not in others. [OBJECTIVE] We examined whether dietary fat modulates the assoc... | null | 2.633 | 390 | Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,002 |
11,755,555 | Increased blood flow and erythema in the posterior vestibular mucosa in vulvar vestibulitis(1). | Obstetrics and gynecology | Obstet Gynecol | 98 | 6 | 10.1016/s0029-7844(01)01578-2 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To evaluate vascular changes as a possible underlying cause of mucosal erythema in women with vulvar vestibulitis. [METHODS] Laser Doppler perfusion imaging was used to map the superficial blood flow in the vestibular mucosa in 20 women with vestibulitis and in 21 healthy control subjects. A possible correl... | null | 1.316 | 268 | Obstetrics and Gynecology | Medicine | 2,001 |
11,754,857 | Severe sepsis induces deficient interferon-gamma and interleukin-12 production, but interleukin-12 therapy improves survival in peritonitis. | American journal of surgery | Am J Surg | 182 | 5 | 10.1016/s0002-9610(01)00754-1 | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] After severe sepsis, there is an increase of Th2 cytokine and a decrease in Th1 cytokine that may account for impaired cellular immunity. The aim of this study is to evaluate the Th1, Th2 cytokine balance in the serum, peritoneal lavage fluid (PLF) and liver mononuclear cells (MNC) of experimental peritoni... | null | 1.205 | 173 | Medicine; Surgery | Medicine | 2,001 |
11,753,982 | Treatment outcome of bone-anchored craniofacial prostheses after tumor surgery. | Cancer | Cancer | 92 | 12 | 10.1002/1097-0142(20011215)92:123045::aid-cncr101473.0.co;2-k | eng | 2,001 | 12 | 15 | null | null | null | [BACKGROUND] Percutaneous endosseous implants have acquired an important place in the prosthetic rehabilitation of patients with craniofacial defects. The objective of this study was to evaluate the clinical outcome of the use of endosseous implants in the orbital and auricular region as well as to assess the satisfact... | null | 1.593 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,753,330 | The short golf backswing: effects on performance and spinal health implications. | Journal of manipulative and physiological therapeutics | J Manipulative Physiol Ther | 24 | 9 | 10.1067/mmt.2001.118982 | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Full recoil golf swings have been implicated in back pain and injury in golfers. Evidence suggests that a restricted backswing may reduce the potential for injury without compromising performance. [OBJECTIVE] To examine both golf swing performance and selected muscular actions of the trunk and shoulder dur... | null | 0.392 | 87 | Chiropractics | Health Professions | 2,001 |
11,753,044 | Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis. | Annals of surgery | Ann Surg | 235 | 1 | 10.1097/00000658-200201000-00009 | eng | 2,002 | 1 | null | null | null | null | [OBJECTIVE] To assess the effect of therapeutic inhibition of interleukin 1beta-converting enzyme (ICE) in an experimental model of severe acute pancreatitis (SAP). [SUMMARY BACKGROUND DATA] Several lines of evidence suggest that cytokines activated by ICE play an instrumental role in the course of acute pancreatitis. ... | null | 3.446 | 360 | Surgery | Medicine | 2,002 |
11,753,018 | Comparison of Amsorb, sodalime, and Baralyme degradation of volatile anesthetics and formation of carbon monoxide and compound a in swine in vivo. | Anesthesiology | Anesthesiology | 96 | 1 | 10.1097/00000542-200201000-00031 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Consequences of volatile anesthetic degradation by carbon dioxide absorbents that contain strong base include formation of compound A from sevoflurane, formation of carbon monoxide (CO) and CO toxicity from desflurane, enflurane and isoflurane, delayed inhalation induction, and increased anesthetic costs. ... | null | null | null | null | null | null |
11,752,815 | The oedema-protective effect of Lycra support stockings. | Dermatology (Basel, Switzerland) | Dermatology | 203 | 4 | 10.1159/000051775 | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Oedema may be an early sign of chronic venous insufficiency (CVI), but swelling of the lower legs is a common phenomenon in many people. The distinction between physiological swelling and CVI is not clear. There is a gradual transition between healthy legs and the early stages of CVI. In case of CVI, medic... | null | 0.641 | 110 | Dermatology | Medicine | 2,001 |
11,752,357 | Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. | The New England journal of medicine | N Engl J Med | 345 | 25 | 10.1056/NEJMoa003199 | eng | 2,001 | 12 | 20 | null | null | null | [BACKGROUND] Patients with arthritis and vascular disease may receive both low-dose aspirin and other nonsteroidal antiinflammatory drugs. We therefore investigated potential interactions between aspirin and commonly prescribed arthritis therapies [METHODS] We administered the following combinations of drugs for six da... | null | 8.571 | 1,231 | Medicine | Medicine | 2,001 |
11,752,012 | Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention. | Journal of the National Cancer Institute | J Natl Cancer Inst | 93 | 24 | 10.1093/jnci/93.24.1872 | eng | 2,001 | 12 | 19 | null | null | null | [BACKGROUND] Human prostate tissues are vulnerable to oxidative DNA damage. The risk of prostate cancer is lower in men reporting higher consumption of tomato products, which contain high levels of the antioxidant lycopene. We examined the effects of consumption of tomato sauce-based pasta dishes on lycopene uptake, ox... | null | 3.925 | 394 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,751,512 | Jab1 expression is associated with inverse expression of p27(kip1) and poor prognosis in epithelial ovarian tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research | Clin Cancer Res | 7 | 12 | null | eng | 2,001 | 12 | null | null | null | null | [PURPOSE] Jab1 (Jun activation domain-binding protein 1) has been described as a coactivtor of AP1 transcription factor, and is a subunit of a large protein complex (called the COP9 signalosome). Recent study (K. Tomoda et al., Nature (Lond.), 398: 160-165, 1999) found that Jab1 protein can cause breakdown of p27(kip1)... | null | 2.121 | 392 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,750,972 | Hysteroscopic treatment of symptomatic submucous fibroids using a bipolar intrauterine system: a feasibility study. | European journal of obstetrics, gynecology, and reproductive biology | Eur J Obstet Gynecol Reprod Biol | 100 | 2 | 10.1016/s0301-2115(01)00485-7 | eng | 2,002 | 1 | 10 | null | null | null | [OBJECTIVE] To determine the feasibility (safety, potential efficacy and cost effectiveness) of a miniature endoscopic bipolar electrosurgical intrauterine system in the treatment of symptomatic submucous fibroids. [STUDY DESIGN] A total of 37 women with symptomatic submucous fibroids were identified on outpatient hyst... | null | null | null | null | null | null |
11,750,962 | Temporal and geographical variation in UK obstetricians' personal preference regarding mode of delivery. | European journal of obstetrics, gynecology, and reproductive biology | Eur J Obstet Gynecol Reprod Biol | 100 | 2 | 10.1016/s0301-2115(01)00468-7 | eng | 2,002 | 1 | 10 | null | null | null | [OBJECTIVE] To assess UK obstetricians' preferences about mode of delivery for themselves or their partners and determine whether these changed since 1995. [STUDY DESIGN] All 313 registered obstetricians in London and one in five (279) sample of those outside London were sent a structured anonymous postal questionnaire... | null | null | null | null | null | null |
11,750,891 | Decreased hippocampal N-acetylaspartate in the absence of atrophy in posttraumatic stress disorder. | Biological psychiatry | Biol Psychiatry | 50 | 12 | 10.1016/s0006-3223(01)01245-8 | eng | 2,001 | 12 | 15 | null | null | null | [BACKGROUND] Previous magnetic resonance imaging studies of posttraumatic stress disorder reported hippocampal volume loss. The goals of this study were 1) to determine the relationship between hippocampal atrophy and posttraumatic stress disorder in the absence of alcohol abuse, and 2) to test if loss of N-acetylaspar... | null | 2.896 | 367 | Biological Psychiatry | Neuroscience | 2,001 |
11,750,277 | Association of polymorphisms of the transforming growth factor-beta1 gene with the rate of progression of HCV-induced liver fibrosis. | Clinica chimica acta; international journal of clinical chemistry | Clin Chim Acta | 316 | 1-2 | 10.1016/s0009-8981(01)00738-0 | eng | 2,002 | 2 | null | null | null | null | [BACKGROUND] The objective of the present study was to elucidate possible relationships between four polymorphisms of the TGF-beta1 gene (-800GA; -509CT; Leu10Pro; Arg25Pro) and stage, histological activity grade and progression rate of liver fibrosis, classified according to the METAVIR-score. [METHODS] Three study gr... | null | null | null | null | null | null |
11,749,866 | Anti-human hepatocellular carcinoma effects of tumor necrosis factor-related apoptosis-inducing ligand in vitro in vivo. | Acta pharmacologica Sinica | Acta Pharmacol Sin | 22 | 9 | null | eng | 2,001 | 9 | null | null | null | null | [AIM] To investigate the effect of over-expression of Bcl-2 protein on Trail protein-induced apoptosis in human hepatoma cells, and the cytotoxicity of Trail protein on human hepatoma cells in vitro and in vivo. [METHODS] The Trail gene was cloned and expressed in E coli. The cytotoxicity of the recombinant Trail prote... | null | 0.294 | 125 | Medicine; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,001 |
11,749,832 | Triptolide inhibits vascular endothelial growth factor expression and production in endothelial cells. | Acta pharmacologica Sinica | Acta Pharmacol Sin | 22 | 7 | null | eng | 2,001 | 7 | null | null | null | null | [AIM] To investigate the effects of triptolide on vascular endothelial growth factor (VEGF) expression and secretion by endothelial cells, and explore the mechanism of anti-proteinuric effect of triptolide on glomerulonephritis. [METHODS] A human umbilical endothelium derived cell line (ECV-304) from American Type Cult... | null | 0.294 | 125 | Medicine; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,001 |
11,749,783 | Ethacrynic acid inhibits pancreatic exocrine secretion. | Acta pharmacologica Sinica | Acta Pharmacol Sin | 22 | 11 | null | eng | 2,001 | 11 | null | null | null | null | [AIM] The effect of ethacrynic acid on pancreatic exocrine secretion function and potential mechanisms of interference with the secretory process in pancreatic acinar cells were investigated. [METHODS] After incubation with ethacrynic acid for 30 min, caerulein-stimulated amylase release and cholecystokinin (CCK) recep... | null | 0.294 | 125 | Medicine; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,001 |
11,748,970 | Role of integrins in invasion of endometrial cancer cell lines. | Gynecologic oncology | Gynecol Oncol | 84 | 1 | 10.1006/gyno.2001.6410 | eng | 2,002 | 1 | null | null | null | null | [OBJECTIVE] The objective of this study was to determine whether there is a link between integrins and components of the plasminogen system, regarding tumor cell invasion to the artificial extracellular matrix. [METHODS] Immunocytochemistry was performed with antibodies directed against integrins alpha2beta1, alpha4bet... | null | 0.994 | 192 | Obstetrics and Gynecology; Oncology | Medicine | 2,002 |
11,748,952 | A randomised controlled trial of micronised purified flavonoid fraction vs placebo in patients with chronic venous disease. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery | Eur J Vasc Endovasc Surg | 23 | 1 | 10.1053/ejvs.2001.1531 | eng | 2,002 | 1 | null | null | null | null | [OBJECTIVE] to evaluate the efficacy of a micronised purified flavonoid fraction (MPFF) in the treatment of chronic venous disease (CVD). [DESIGN] prospective double blind, randomised, control study. [PATIENTS AND METHODS] one hundred and one patients with symptomatic CVD were randomly allocated to treatment for 60 day... | null | 0.84 | 144 | Cardiology and Cardiovascular Medicine; Surgery | Medicine | 2,002 |
11,732,952 | Metered-dose inhaler: the emergency department orphan. | Archives of pediatrics adolescent medicine | Arch Pediatr Adolesc Med | 155 | 12 | 10.1001/archpedi.155.12.1335 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] Physicians providing emergency department care to children primarily use nebulizers for the delivery of bronchodilators and these physicians have misconceptions regarding the advantages and disadvantages of using metered-dose inhalers (MDIs) with a spacer (MDI + S) for acute asthma exacerbations. [DESIGN] S... | null | null | null | null | null | null |
11,748,403 | Anesthetic effects on mitochondrial ATP-sensitive K channel. | Anesthesiology | Anesthesiology | 95 | 6 | 10.1097/00000542-200112000-00024 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Volatile anesthetics show an ischemic preconditioning-like cardioprotective effect, whereas intravenous anesthetics have cardioprotective effects for ischemic-reperfusion injury. Although recent evidence suggests that mitochondrial adenosine triphosphate-regulated potassium (mitoK(ATP)) channels are import... | null | null | null | null | null | null |
11,747,766 | Increment of calcium-activated and delayed rectifier potassium current by hyposmotic swelling in gastric antral circular myocytes of guinea pig. | Acta pharmacologica Sinica | Acta Pharmacol Sin | 22 | 6 | null | eng | 2,001 | 6 | null | null | null | null | [AIM] To observe the effect of hyposmotic swelling on calcium-activated potassium current [IKCa] and delayed rectifier potassium current [IKV] in gastric antral circular myocytes of guinea pig. [METHODS] The whole cell patch-clamp technique was used, and the myocytes were isolated by collagenase. Cells were swelled by ... | null | 0.294 | 125 | Medicine; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,001 |
11,747,753 | Identification of Atractylodes plants in Chinese herbs and formulations by random amplified polymorphic DNA. | Acta pharmacologica Sinica | Acta Pharmacol Sin | 22 | 6 | null | eng | 2,001 | 6 | null | null | null | null | [AIM] An efficient, precise, and sensitive method for identifying Atractylodes plants has been established and will contribute significantly to quality control and scientific analysis in Chinese traditional medicine. [METHODS] Twenty primers were applied for setting up the RAPD (randomly amplified polymorphic DNA) mark... | null | 0.294 | 125 | Medicine; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,001 |
11,747,470 | Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices. | BMC neuroscience | BMC Neurosci | 2 | null | 10.1186/1471-2202-2-18 | eng | 2,001 | null | null | 2,001 | 11 | 28 | [BACKGROUND] Recently a hyperthermic rat hippocampal slice model system has been used to investigate febrile seizure pathophysiology. Our previous data indicates that heating immature rat hippocampal slices from 34 to 41 degrees C in an interface chamber induced epileptiform-like population spikes accompanied by a spre... | null | 0.121 | 116 | Cellular and Molecular Neuroscience; Neuroscience | Neuroscience | 2,001 |
11,745,804 | Resection margin status in lumpectomy specimens for duct carcinoma of the breast: correlation with core biopsy and mammographic findings. | Journal of surgical oncology | J Surg Oncol | 78 | 3 | 10.1002/jso.1147 | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] The strategy for surgical treatment of breast carcinoma proven by biopsy is mainly based on the physical and mammographic examinations. To investigate if the pathological findings in core biopsy are contributory to planning the surgical strategy, we correlated the status of ductal carcinoma in situ (DCIS) ... | null | 0.764 | 136 | Medicine; Surgery; Oncology | Medicine | 2,001 |
11,745,189 | The incidence of thanatophoric dysplasia mutations in FGFR3 gene is higher in low-grade or superficial bladder carcinomas. | Cancer | Cancer | 92 | 10 | 10.1002/1097-0142(20011115)92:102555::aid-cncr16073.0.co;2-m | eng | 2,001 | 11 | 15 | null | null | null | [BACKGROUND] The point mutations of fibroblast growth factor receptor 3 (FGFR3) are associated with autosomal dominant human skeletal disorders such as thanatophoric dysplasia (TD). However, point mutations were reported in a small series of bladder carcinomas, suggesting their oncogenic role. In view of these findings... | null | 1.593 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,745,060 | Aortic valve replacement with a stentless bioprosthesis using the full-root technique. | The Thoracic and cardiovascular surgeon | Thorac Cardiovasc Surg | 49 | 6 | 10.1055/s-2001-19014 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] In aortic valve replacement stentless bioprostheses results in improved hemodynamic function compared to stented valves. Using the root replacement technique even larger prostheses are implantable. We present our experience with stentless bioprostheses implanted in the "full-root" technique. [PATIENTS AND ... | null | 0.551 | 60 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,001 |
11,744,966 | Malnutrition in children with congenital heart defects. | Saudi medical journal | Saudi Med J | 22 | 11 | null | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVE] To assess the frequency of malnutrition in children with congenital heart defects in a hospital outpatient setting. [METHODS] One hundred and fifty-two children with congenital heart defects (patients), and an equal number of children with innocent cardiac murmurs (controls) attending the Pediatric Cardiolo... | null | null | null | null | null | null |
11,744,909 | Harvesting autologous fascia lata for pelvic reconstructive surgery: techniques and morbidity. | American journal of obstetrics and gynecology | Am J Obstet Gynecol | 185 | 6 | 10.1067/mob.2001.119074 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To determine donor site morbidity associated with harvesting of fascia lata. [STUDY DESIGN] We reviewed medical records and evaluated responses to mailed questionnaires from all patients who underwent fascia lata harvesting during a 54-month period. Data were collected about immediate complications and long... | null | 1.601 | 274 | Obstetrics and Gynecology | Medicine | 2,001 |
11,744,591 | Patients' perceptions of cardiac anesthesia services: a pilot study. | Canadian journal of anaesthesia = Journal canadien d'anesthesie | Can J Anaesth | 48 | 11 | 10.1007/BF03020381 | eng | 2,001 | 12 | null | null | null | null | [PURPOSE] To develop an instrument to measure patients' perceptions of the services provided by anesthesiologists, an important indicator of quality for which little information is available. [METHODS] The scale of patients' perceptions of cardiac anesthesia services (SOPPCAS) is composed of 17 Likert-type and sociodem... | null | null | null | null | null | null |
11,744,562 | Effect of seeing tobacco use in films on trying smoking among adolescents: cross sectional study. | BMJ (Clinical research ed.) | BMJ | 323 | 7326 | 10.1136/bmj.323.7326.1394 | eng | 2,001 | 12 | 15 | null | null | null | [OBJECTIVE] To test the hypothesis that greater exposure to smoking in films is associated with trying smoking among adolescents. [DESIGN] Cross sectional survey of 4919 schoolchildren aged 9-15 years, and assessment of occurrence of smoking in 601 films. [SETTING] Randomly selected middle schools in Vermont and New Ha... | null | 1.152 | 519 | Medicine | Medicine | 2,001 |
11,744,485 | Is postoperative cystography necessary after ureteral reimplantation? | Urology | Urology | 58 | 6 | 10.1016/s0090-4295(01)01467-4 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVES] To evaluate the patients in our practice to determine whether postoperative cystography was useful in monitoring the outcome after ureteroneocystostomy. Surgical repair of vesicoureteral reflux is the treatment of choice after medical therapy failure. Radiographic evaluation by ultrasonography or voiding c... | null | 1.399 | 197 | Urology | Medicine | 2,001 |
11,743,504 | Cow's milk protein-sensitive enteropathy at school age. | The Journal of pediatrics | J Pediatr | 139 | 6 | 10.1067/mpd.2001.118882 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVES] Cow's milk protein-sensitive enteropathy (CMSE) may persist in children to school age. We sought to define the morphologic and immunohistochemical features of persistent CMSE. [STUDY DESIGN] We studied 15 children with a definite diagnosis of CMSE on the basis of a blind challenge, 12 children with suspect... | null | 1.633 | 246 | Pediatrics, Perinatology and Child Health | Medicine | 2,001 |
11,743,286 | Neoadjuvant androgen ablation before radical prostatectomy in cT2bNxMo prostate cancer: 5-year results. | The Journal of urology | J Urol | 167 | 1 | null | eng | 2,002 | 1 | null | null | null | null | [PURPOSE] In the initial report of the Lupron Depot Neoadjuvant Prostate Cancer Study Group patients who received 3 months of androgen deprivation had a significant decrease in the positive margin rate. We monitored these patients for 5 years and to our knowledge present the longest followup of any neoadjuvant trial. [... | null | 1.629 | 291 | Urology | Medicine | 2,002 |
11,743,279 | Cost-effectiveness of a modified care protocol substituting bladder tumor markers for cystoscopy for the followup of patients with transitional cell carcinoma of the bladder: a decision analytical approach. | The Journal of urology | J Urol | 167 | 1 | null | eng | 2,002 | 1 | null | null | null | null | [PURPOSE] Decision analysis models were established to determine the cost-effectiveness of a plan alternating a bladder tumor marker with cystoscopy and cytology at 3-months intervals or modified care versus followup cystoscopy and cytology every 3 months or standard care. [MATERIALS AND METHODS] We performed a compreh... | null | 1.629 | 291 | Urology | Medicine | 2,002 |
11,742,917 | Pulmonary infectious mortality among patients with end-stage renal disease. | Chest | Chest | 120 | 6 | 10.1378/chest.120.6.1883 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Infection is the second-leading cause of death among patients with end-stage renal disease (ESRD). This is due in part to advanced age, comorbid conditions, and immune dysfunction observed in uremic states. Although one may hypothesize that pulmonary infectious mortality is higher among patients with ESRD ... | null | 0.916 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,001 |
11,742,437 | Health-related quality of life in individuals infected with HIV in the era of HAART. | HIV clinical trials | HIV Clin Trials | 2 | 6 | 10.1310/48ET-TT7G-35RA-D4C3 | eng | 2,001 | null | null | null | null | null | [PURPOSE] To compare health-related quality of life (HR-QOL) in individuals infected with HIV to general population levels and to assess the relationship between HR-QOL and markers of disease progression in the era of highly active antiretroviral therapy (HAART). [METHOD] This was a cross-sectional questionnaire-based ... | null | null | null | null | null | null |
11,742,321 | Risk of malignancy in thyroid incidentalomas identified by fluorodeoxyglucose-positron emission tomography. | Surgery | Surgery | 130 | 6 | 10.1067/msy.2001.118265 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Thyroid tumors often exhibit increased metabolic activity, as evidenced by enhanced glucose uptake on positron emission tomography (PET) with use of (18)F-fluorodeoxyglucose (FDG). The incidence of new thyroid lesions found on routine FDG-PET has not been previously reported. [METHODS] A retrospective revi... | null | null | null | null | null | null |
11,740,800 | Hemodynamic instability in chronic fatigue syndrome: indices and diagnostic significance. | Seminars in arthritis and rheumatism | Semin Arthritis Rheum | 31 | 3 | 10.1053/sarh.2001.27738 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVES] To evaluate the cardiovascular response to postural challenge in patients with chronic fatigue syndrome (CFS) and to determine whether the degree of instability of the cardiovascular response may aid in diagnosing CFS. [METHODS] Patients with CFS (n = 25) and their age- and gender-matched healthy controls ... | null | 1.067 | 139 | Anesthesiology and Pain Medicine; Rheumatology | Medicine | 2,001 |
11,740,485 | Changes in the pattern of horseradish peroxidase diffusion into predentin and dentin after cavity preparation in rat molars. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | 92 | 6 | 10.1067/moe.2001.117264 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] The purpose of this study was to examine the process of reducing dentin permeability in adult rat molars after cavity preparation with horseradish peroxidase as a tracer. [STUDY DESIGN] Class V cavities were prepared on the upper first molars of 18 rats. Horseradish peroxidase was injected into the vascular... | null | null | null | null | null | null |
11,740,374 | Early fracture of the sacrum or pelvis: an unusual complication after multilevel instrumented lumbosacral fusion. | Spine | Spine (Phila Pa 1976) | 26 | 24 | 10.1097/00007632-200112150-00027 | eng | 2,001 | 12 | 15 | null | null | null | [STUDY DESIGN] A retrospective review of a series of cases with a complication of instrumented lumbosacral fusion. [OBJECTIVES] To present a previously undescribed complication, early sacral or pelvic stress fracture, after instrumented lumbosacral fusion and to identify the risk factors associated with this complicati... | null | 1.078 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,001 |
11,739,971 | Collateral ability of the circle of Willis in patients with unilateral internal carotid artery occlusion: border zone infarcts and clinical symptoms. | Stroke | Stroke | 32 | 12 | 10.1161/hs1201.099892 | eng | 2,001 | 12 | 1 | null | null | null | [BACKGROUND AND PURPOSE] The circle of Willis is regarded as the major source of collateral flow in patients with severe carotid artery disease. The purpose of the present study was to assess whether the presence of border zone infarcts is related to the collateral ability of the circle of Willis in symptomatic (transi... | null | 3.022 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,001 |
11,739,970 | Matrix metalloproteinase expression is related to hemorrhagic transformation after cardioembolic stroke. | Stroke | Stroke | 32 | 12 | 10.1161/hs1201.99512 | eng | 2,001 | 12 | 1 | null | null | null | [BACKGROUND AND PURPOSE] In animal models of cerebral ischemia, matrix metalloproteinase (MMP) expression was significantly increased and related to blood-brain barrier disruption, edema formation, and hemorrhagic transformation (HT). MMP inhibitors reduce HT after embolic ischemia in tissue-type plasminogen activator-... | null | 3.022 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,001 |
11,739,829 | Prospective longitudinal assessment of hallucinations in Parkinson's disease. | Neurology | Neurology | 57 | 11 | 10.1212/wnl.57.11.2078 | eng | 2,001 | 12 | 11 | null | null | null | [OBJECTIVE] To monitor the evolution of hallucinations over 4 years in a stratified sample of patients with PD. [METHODS] Using a modified version of the Unified PD Rating Scale (UPDRS) Thought Disorder question, the authors stratified patients into five baseline behavioral groups. They recruited up to 20 patients for ... | null | 2.19 | 422 | Neurology | Medicine | 2,001 |
11,739,823 | Respiratory function vs sleep-disordered breathing as predictors of QOL in ALS. | Neurology | Neurology | 57 | 11 | 10.1212/wnl.57.11.2040 | eng | 2,001 | 12 | 11 | null | null | null | [BACKGROUND] Most patients with ALS have evidence of respiratory muscle weakness at diagnosis, and death is usually due to respiratory failure. Sleep disruption, possibly due to apneas, hypopneas, orthopnea, or REM-related desaturation, is common. The relative impact of these factors on quality of life has not been est... | null | 2.19 | 422 | Neurology | Medicine | 2,001 |
11,739,343 | On the relationship between the efficiency and the quality of the consultation. A validity study. | Family practice | Fam Pract | 18 | 6 | 10.1093/fampra/18.6.592 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVES] The aim of this study was to determine how the medical performance of physicians during consultations is related to doctor-patient communication and satisfaction of patients, taking into account the actual length of the consultations. In addition, we studied the validity of the 'efficiency-per-time score' ... | null | 1.006 | 116 | Family Practice | Medicine | 2,001 |
11,738,763 | Respiratory syncytial virus vaccine: a systematic overview with emphasis on respiratory syncytial virus subunit vaccines. | Vaccine | Vaccine | 20 | 5-6 | 10.1016/s0264-410x(01)00388-7 | eng | 2,001 | 12 | 12 | null | null | null | [OBJECTIVE] To explore whether RSV vaccines are efficacious in preventing respiratory syncytial virus (RSV) lower respiratory infection (LRI). [METHODS] Randomized clinical trials were sought through Medline using the following search terms: "RSV" or "RSV infection" and "viral vaccine". Randomized controlled trials in ... | null | 1.012 | 222 | Immunology and Microbiology; Infectious Diseases; Public Health, Environmental and Occupational Health; Veterinary; Molecular Medicine | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Veterinary | 2,001 |
11,738,393 | Biochemical profile and survival in nonagenarians. | Clinical biochemistry | Clin Biochem | 34 | 7 | 10.1016/s0009-9120(01)00261-2 | eng | 2,001 | 10 | null | null | null | null | [OBJECTIVES] Old age is associated with an increase in frequency of disorders involving virtually all organ systems, resulting in a rise of mortality. The aim of the project was to study the relationship between biochemical markers and all-cause mortality in a defined age group. [DESIGN AND METHODS] Thirty-eight nonage... | null | 0.526 | 130 | Medicine; Clinical Biochemistry | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,737,924 | Practising evidence-based medicine: the design and implementation of a multidisciplinary team-driven extubation protocol. | Critical care (London, England) | Crit Care | 5 | 6 | 10.1186/cc1068 | eng | 2,001 | 12 | null | 2,001 | 10 | 26 | [BACKGROUND] Evidence from recent literature shows that protocol-directed extubation is a useful approach to liberate patients from mechanical ventilation (MV). However, research evidence does not necessarily provide guidance on how to implement changes in individual intensive care units (ICUs). We conducted the presen... | null | 0.144 | 229 | Critical Care and Intensive Care Medicine | Medicine | 2,001 |
11,737,627 | The microbiological examination of ready-to-eat organic vegetables from retail establishments in the United Kingdom. | Letters in applied microbiology | Lett Appl Microbiol | 33 | 6 | 10.1046/j.1472-765x.2001.01026.x | eng | 2,001 | 12 | null | null | null | null | [AIMS] A microbiological study of uncooked ready-to-eat organic vegetables was undertaken to determine the microbiological quality of these vegetables on retail sale in the UK. [METHODS AND RESULTS] Organic vegetables were collected and examined according to a standardized protocol. The majority (3185 of 3200; 99.5%) o... | null | 0.672 | 133 | Applied Microbiology and Biotechnology | Immunology and Microbiology | 2,001 |
11,737,509 | Effect of a polyhexamethylene biguanide mouthrinse on bacterial counts and plaque. | Journal of clinical periodontology | J Clin Periodontol | 28 | 12 | 10.1034/j.1600-051x.2001.281206.x | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVES] For various clinical applications, polyhexamethylene biguanide (PHMB) has been used for many years as an antiseptic in medicine. Little is known, however, of its antibacterial activity in the oral cavity and its ability to inhibit plaque formation. In this study, a 0.04% PHMB mouthrinse (A) was compared wi... | null | 0.962 | 187 | Periodontics | Dentistry | 2,001 |
11,737,309 | Pleomorphic lobular carcinoma of the breast: its cell kinetics, expression of oncogenes and tumour suppressor genes compared with invasive ductal carcinomas and classical infiltrating lobular carcinomas. | Histopathology | Histopathology | 39 | 5 | 10.1046/j.1365-2559.2001.01252.x | eng | 2,001 | 11 | null | null | null | null | [AIMS] The study addresses whether pleomorphic lobular breast carcinomas represent a distinct entity with respect to proliferation and apoptosis as well the expression of the p53, bcl-2 and Her2 protein. [METHODS AND RESULTS] The study included 30 cases of pleomorphic lobular carcinoma (PLC; G2 n=15, G3 n=15). Poorly d... | null | 0.923 | 145 | Histology; Medicine; Pathology and Forensic Medicine | Medicine | 2,001 |
11,737,269 | Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7. | Genes to cells : devoted to molecular cellular mechanisms | Genes Cells | 6 | 12 | 10.1046/j.1365-2443.2001.00483.x | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] BMP2 is known to play a wide variety of roles, including some in the development of the nervous system. This cytokine has been reported to induce neurite outgrowth in rat pheochromocytoma PC12 cells via the activation of a p38 MAP kinase, although its regulatory mechanism remains largely to be elucidated. ... | null | null | null | null | null | null |
11,737,236 | Heterogeneity of smooth muscle cells in advanced human atherosclerotic plaques: intimal smooth muscle cells expressing a fibroblast surface protein are highly activated by platelet-released products. | European journal of clinical investigation | Eur J Clin Invest | 31 | 11 | 10.1046/j.1365-2362.2001.00920.x | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] In vascular disease, smooth muscle cells (SMC) undergo phenotypic modulation and may acquire properties resembling those of fibroblasts in tissue wound healing. [AIMS] We aimed to show the differential expression of a fibroblast surface protein (FSP) by SMC in atherosclerotic lesions. [RESULTS] In early hu... | null | 0.874 | 126 | Clinical Biochemistry; Medicine; Biochemistry | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,737,043 | The influence of inhalative corticosteroids on circulating Nerve Growth Factor, Brain-Derived Neurotrophic Factor and Neurotrophin-3 in allergic asthmatics. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology | Clin Exp Allergy | 31 | 12 | 10.1046/j.1365-2222.2001.01249.x | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] The neurotrophins Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin (NT)-3 are produced, stored and released by various immunological cells. The influence of NTs upon the function of these cells is described. Elevated plasma levels were found in inflammatory, autoimmune a... | null | 1.529 | 176 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,001 |
11,737,038 | Distribution of HLA-A, B alleles and polymorphisms of TAP and LMP genes in Korean patients with atopic dermatitis. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology | Clin Exp Allergy | 31 | 12 | 10.1046/j.1365-2222.2001.01042.x | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Atopic dermatitis has been seen to result from multifactorial inheritance, with interaction between genetic and environmental factors. The genetic association may differ according to the ethnic backgrounds. [OBJECTIVE] The purpose of this study was to investigate the genetic factors in Korean atopic dermat... | null | 1.529 | 176 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,001 |
11,735,759 | Guided medication dosing for inpatients with renal insufficiency. | JAMA | JAMA | 286 | 22 | 10.1001/jama.286.22.2839 | eng | 2,001 | 12 | 12 | null | null | null | [CONTEXT] Usual drug-prescribing practices may not consider the effects of renal insufficiency on the disposition of certain drugs. Decision aids may help optimize prescribing behavior and reduce medical error. [OBJECTIVE] To determine if a system application for adjusting drug dose and frequency in patients with renal... | null | null | null | null | null | null |
11,735,200 | A new device for the measurement of disease severity in patients with intermittent claudication. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery | Eur J Vasc Endovasc Surg | 22 | 6 | 10.1053/ejvs.2001.1528 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVES] To assess a new method of determining functional impairment in patients with intermittent claudication, the Double Physiological Walking Test (DPWT) using the PADHOC (Peripheral Arterial Disease Holter Control) device, against a standard treadmill test. [DESIGN] Patients with intermittent claudication pres... | null | 1.075 | 144 | Cardiology and Cardiovascular Medicine; Surgery | Medicine | 2,001 |
11,735,184 | A 16-year haemodynamic follow-up of women with pregnancy-related medically treated iliofemoral deep venous thrombosis. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery | Eur J Vasc Endovasc Surg | 22 | 5 | 10.1053/ejvs.2001.1499 | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVES] to evaluate clinical and functional long-term outcomes following pregnancy-related medically treated iliofemoral deep venous thrombosis (DVT). [DESIGN] retrospective follow-up of patients identified through a registry search. [MATERIAL AND METHODS] twenty-five women underwent clinical examination, colour d... | null | 1.075 | 144 | Cardiology and Cardiovascular Medicine; Surgery | Medicine | 2,001 |
11,733,956 | Types and duration of symptoms prior to diagnosis of invasive or borderline ovarian tumor. | Gynecologic oncology | Gynecol Oncol | 83 | 3 | 10.1006/gyno.2001.6411 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] The objective was to describe and compare types and duration of symptoms among women with invasive versus borderline ovarian tumors. [METHODS] Cases were women, ages 20-69 years, diagnosed with invasive (616) and borderline (151) epithelial ovarian tumors from 1994 to 1998. Symptoms were obtained using a st... | null | 0.895 | 192 | Obstetrics and Gynecology; Oncology | Medicine | 2,001 |
11,733,955 | Vulvar melanoma: a retrospective analysis and literature review. | Gynecologic oncology | Gynecol Oncol | 83 | 3 | 10.1006/gyno.2001.6337 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] This review focuses on current directions in the staging and treatment of melanoma of the vulva. [METHODS] All women treated for invasive melanoma of the vulva at the University of Virginia Health Sciences Center from 1980 through 2000 were identified through a retrospective review of the records of the Div... | null | 0.895 | 192 | Obstetrics and Gynecology; Oncology | Medicine | 2,001 |
11,733,903 | Recurrent congenital diaphragmatic hernia: A novel repair. | Journal of pediatric surgery | J Pediatr Surg | 36 | 12 | 10.1053/jpsu.2001.28818 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND/PURPOSE] Repair of recurrent diaphragmatic hernia continues to be a difficult problem. An innovative method using a nonabsorbable polypropylene prosthetic mesh plug placed via the thoracic approach using minimal dissection is presented. [METHODS] A retrospective analysis showed 39 children with congenital d... | null | 0.804 | 147 | Medicine; Pediatrics, Perinatology and Child Health; Surgery | Medicine | 2,001 |
11,733,901 | Total colonic manometry as a guide for surgical management of functional colonic obstruction: Preliminary results. | Journal of pediatric surgery | J Pediatr Surg | 36 | 12 | 10.1053/jpsu.2001.28815 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND/PURPOSE] Functional colonic obstruction (pseudo-obstruction) encompasses a broad group of motility disorders. Medical management of colonic pseudo-obstruction is complex and often fails, leading to surgical referral. In most cases (excepting Hirschsprung's disease) the surgeon is unable to precisely localiz... | null | 0.804 | 147 | Medicine; Pediatrics, Perinatology and Child Health; Surgery | Medicine | 2,001 |
11,733,426 | Local television news coverage of traumatic deaths and injuries. | The Western journal of medicine | West J Med | 175 | 6 | 10.1136/ewjm.175.6.380 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To assess how local television news programs' reporting of injuries and deaths from traumatic causes compares with coroners' records of deaths and the estimated incidence of injuries in the same geographic area during the same time. [METHODS] Using epidemiologic methods, we identified the underlying cause o... | null | null | null | null | null | null |
11,732,558 | Statistical methods in epidemiology. VII. An overview of the chi2 test for 2 x 2 contingency table analysis. | Disability and rehabilitation | Disabil Rehabil | 23 | 16 | 10.1080/09638280110060457 | eng | 2,001 | 11 | 10 | null | null | null | [PURPOSE] The odds ratio is an appropriate method of analysis for data in 2 x 2 contingency tables. However, other methods of analysis exist. One such method is based on the chi2 test of goodness-of-fit. Key players in the development of statistical theory include Pearson, Fisher and Yates. [METHOD] Data are presented ... | null | 0.442 | 140 | Rehabilitation | Medicine | 2,001 |
11,731,861 | The management of residual and recurrent intracranial aneurysms after previous endovascular or surgical treatment--a report of eighteen cases. | Acta neurochirurgica | Acta Neurochir (Wien) | 143 | 11 | 10.1007/s007010100001 | eng | 2,001 | 11 | null | null | null | null | [OBJECT] We wish to report our experience in the management of residual or recurrent intracranial aneurysm after previous endovascular or surgical treatment. [METHODS] We performed a retrospective review of the clinical notes, operation records and cerebral angiograms of eighteen patients who were known to have undergo... | null | 0.581 | 112 | Surgery; Neurology | Medicine | 2,001 |
11,730,743 | Assessment of early cleaving in vitro fertilized human embryos at the 2-cell stage before transfer improves embryo selection. | Fertility and sterility | Fertil Steril | 76 | 6 | 10.1016/s0015-0282(01)02901-6 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To determine the most viable embryos for transfer. [DESIGN] Study 1: Preselection of early-cleaving 2-cell embryos for transfer. Study 2: Alternating weeks during which preselection was performed and not performed. [SETTING] ART program, Birmingham Women's Hospital, Birmingham, United Kingdom. [PATIENT(S)] ... | null | 1.354 | 252 | Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,001 |
11,730,742 | A randomized study comparing Crinone 8% and intramuscular progesterone supplementation in in vitro fertilization-embryo transfer cycles. | Fertility and sterility | Fertil Steril | 76 | 6 | 10.1016/s0015-0282(01)02872-2 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To compare the efficacy of Crinone 8% intravaginal progesterone gel vs. IM progesterone for luteal phase and early pregnancy support after IVF-ET. [DESIGN] Randomized, open-label study. [SETTING] Academic medical center. [PATIENT(S)] Two hundred and one women undergoing IVF-ET. [INTERVENTION(S)] Women were ... | null | 1.354 | 252 | Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,001 |
11,730,735 | Absorption and preferential vagina-to-uterus distribution after vaginal administration of (99m)Tc-pertechnetate in postmenopausal women. | Fertility and sterility | Fertil Steril | 76 | 6 | 10.1016/s0015-0282(01)02905-3 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To investigate in vivo and in humans the mechanisms and kinetics of vagina-to-uterus distribution. [DESIGN] Controlled clinical study. [SETTING] Volunteers in an academic research environment. [PATIENT(S)] Six postmenopausal women undergoing transabdominal hysterectomy were selected. [INTERVENTION(S)] Women... | null | 1.354 | 252 | Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,001 |
11,730,669 | Efficacy of (123)N-isopropyl-p-[(123)I]-iodoamphetamine single photon emission computed tomography for the diagnosis of uveal malignant melanoma. | American journal of ophthalmology | Am J Ophthalmol | 132 | 6 | 10.1016/s0002-9394(01)01142-4 | eng | 2,001 | 12 | null | null | null | null | [PURPOSE] To evaluate the efficacy of single photon emission computed tomography (SPECT) images with N-isopropyl-p-[(123)I]-iodoamphetamine ([(123)I]-IMP) as a radiopharmaceutical for the diagnosis of uveal melanoma. [METHODS] Consecutive interventional case series. Single photon emission computed tomography images wer... | null | 1.651 | 221 | Ophthalmology | Medicine | 2,001 |
11,730,660 | Epstein-Barr virus dacryoadenitis resulting in keratoconjunctivitis sicca in a child. | American journal of ophthalmology | Am J Ophthalmol | 132 | 6 | 10.1016/s0002-9394(01)01182-5 | eng | 2,001 | 12 | null | null | null | null | [PURPOSE] To describe a case of severe dry eye syndrome in a child. [METHODS] Observational case report. The authors describe a 10-year-old male with severe dry eyes who was profoundly disabled by pain and photophobia despite aggressive conventional therapy. Lacrimal gland histology was consistent with the primary Sjög... | null | 1.651 | 221 | Ophthalmology | Medicine | 2,001 |
11,730,500 | Fetal heart rate patterns in normal and ritodrine-treated pregnancies, detected by magnetocardiography. | The Journal of maternal-fetal medicine | J Matern Fetal Med | 10 | 5 | 10.1080/714052759 | eng | 2,001 | 10 | null | null | null | null | [OBJECTIVE] The aim of the present study was to test the validity of magnetocardiography in the diagnosis of fetal heart rate arrhythmias in normal pregnancies, as compared to the number of arrhythmias reported in other series, which were detected by use of other diagnostic techniques. We also evaluated the influence o... | null | null | null | null | null | null |
11,730,491 | Outcome of infants delivered between 24 and 28 weeks' gestation in women with severe pre-eclampsia. | The Journal of maternal-fetal medicine | J Matern Fetal Med | 10 | 5 | 10.1080/714904350 | eng | 2,001 | 10 | null | null | null | null | [OBJECTIVE] To determine whether there are differences in neonatal outcome between infants born to mothers with severe pre-eclampsia and those born to normotensive mothers with preterm labor and intact membranes between 24 and 28 weeks' gestation. [MATERIALS AND METHODS] Over a 4-year period between 1991 and 1995, neon... | null | null | null | null | null | null |
11,730,183 | Effective control of asthma with hydrofluoroalkane flunisolide delivered as an extrafine aerosol in asthma patients. | Annals of allergy, asthma immunology : official publication of the American College of Allergy, Asthma, Immunology | Ann Allergy Asthma Immunol | 87 | 5 | 10.1016/S1081-1206(10)62922-5 | eng | 2,001 | 11 | null | null | null | null | [BACKGROUND] Inhaled corticosteroids are established as maintenance therapy for persistent asthma. A new aerosol formulation of flunisolide delivers a small particle size by using a hydrofluoroalkane (HFA) propellant with a built-in spacer. [OBJECTIVE] To compare efficacy and safety of two different flunisolide formula... | null | null | null | null | null | null |
11,729,519 | Nasal carriage of Streptococcus pneumoniae among children in Beijing. | Chinese medical journal | Chin Med J (Engl) | 114 | 11 | null | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVE] To investigate the antimicrobial susceptibility of Streptococcus pneumoniae carried in the nose among children in Beijing and the distribution of serotypes, and to analyze the risk factors for nasal carriage of penicillin non-susceptible S. pneumoniae. [METHODS] A disk diffusion test was applied to detect t... | null | 0.127 | 84 | Medicine | Medicine | 2,001 |
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