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accommodates one glomerulus,is lined by a single layer of squamous |
epithelial cells called podocyte cells. There are fine pores between |
podocyte cells to allow passage of materials filtered out of glomerulus. |
LA afferent arteriole |
malpighian body |
efferent arteriole |
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null |
cortex |
glomerulus { Bowman’s capsule |
first convoluted tubule |
TE |
null |
medulla |
second convoluted |
tubule |
renal artery |
renal vein |
collecting duct |
nephron ureter |
loop of Henle |
T |
null |
null |
capillary network |
calyces |
pelvis |
pelvis |
open to pelvis |
ER |
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null |
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fig-5: Internal structure of kidney |
fig-6: Structure of a nephron |
Renal tubule: It has three parts. First or proximal convoluted tubule (PCT), |
loop of Henle, which is U shaped, second or distal convoluted tubule (DCT). |
Distal convoluted tubules open into a collecting tube. Collecting tube |
SC |
null |
null |
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form pyramids and calyces which open into the pelvis. Pelvis leads into |
the ureter. All the parts of the renal tubule are covered by a network of |
peritubular (around tube) capillaries formed from efferent arteriole. The |
peritubular capillaries join to form renal venule, which joins the other |
venules to form finally the renal vein. |
Why the nephron is considered to be the structural and functional |
unit of the kidney? |
Free distribution by T.S. Government 2019-20 79 |
Mechanisms of urine formation |
Formation of urine involves four stages i. Glomerular filtration, |
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A |
ii.Tubular reabsorption, iii. Tubular secretion, iv.Concentration of urine |
i) Glomerular filtration |
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null |
null |
null |
AN |
Blood flows from renal artery to glomerulus through afferent arteriole. |
Observe the fig-7 of glomerular filtration in nephron and try to answer the |
following questions. |
Which arteriole has moree diameter, afferent or efferent? |
What are the substances that are filtered into the glomerular capsule? |
null |
null |
null |
null |
NG |
ii) Tubular Re-absorption |
Filtrate from glomerular is also called primary urine which almost equal |
to blood in chemical composition except the presence of blood cells. It |
passes into proximal convoluted tubule. Useful substances in primary urine |
are reabsorbed into peritubular net work. |
LA |
If you drink moree water will you pass more urine? |
What are the substances reabsorbed into peritubular net work from |
proximal convoluted tubule (PCT)? |
iii) Tubular secretion |
TE |
null |
After reabsorption in PCT region, the urine travels through the loop |
DCT. Here some other wastes like extra salts ions of K+ Na+ |
of Henle into DCT. |
Cl – and H+ secretes from peritubular capillaries in to DCT. It occurs mostly |
in the distal convoluted tubule, which is also surrounded by peritubular |
capillaries. This maintains a proper concentration and pH of the urine. |
T |
null |
null |
Smaller amount of tubular secretion also takes place in the area of proximal |
convoluted tubule. Observe tubular secretion in fig-7. |
ER |
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