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### Question: Is duration of postoperative fasting associated with infection and prolonged length of stay in surgical patients? ### Context: Verify whether the postoperative fasting period increases the risk for infection and prolonged length of stay.Prospective cohort study. Elective surgery patients were included. Ex... |
### Question: Does maximal leg-strength training improve cycling economy in previously untrained men? ### Context: This study examined cycling economy before and after 8 wk of maximal leg-strength training.Seven previously untrained males (25 +/- 2 yr) performed leg-strength training 3 d.wk(-1) for 8 wk using four sets... |
### Question: Does high tissue-transglutaminase antibody level predict small intestinal villous atrophy in adult patients at high risk of celiac disease? ### Context: Duodenal biopsy may be unnecessary to confirm celiac disease in patients with high tissue-transglutaminase antibody level.To define a cut-off value of ti... |
### Question: Does radiologic progression of pulmonary infiltrates predict a worse prognosis in severe community-acquired pneumonia than bacteremia? ### Context: It remains unknown whether bacteremia and rapid radiologic progression of pulmonary infiltrates increase the risk of shock and mortality in ICU patients with ... |
### Question: Does inhibition of type 5 phosphodiesterase counteract β2-adrenergic signalling in beating cardiomyocytes? ### Context: Compartmentalization of cAMP and PKA activity in cardiac muscle cells plays a key role in maintaining basal and enhanced contractility stimulated by sympathetic nerve activity. In cardio... |
### Question: Does life style modification improve insulin resistance and liver histology in patients with non-alcoholic fatty liver disease? ### Context: To study the effect of regular aerobic exercise on insulin resistance, serum aminotransferase and liver histology in nonalcoholic fatty liver disease (NAFLD) patient... |
### Question: Does doxycycline block gastric ulcer by regulating matrix metalloproteinase-2 activity and oxidative stress? ### Context: To examine the effect of doxycycline on the activity of matrix metalloproteinases (MMPs) and oxidative stress in gastric tissues of rats following gastric injury.Gastric ulcers were ge... |
### Question: Does rat granulation tissue maturation involve gap junction communications? ### Context: Wound healing, a coordinated process, proceeds by sequential changes in cell differentiation and terminates with the deposition of a new connective tissue matrix, a scar. Initially, there is the migratory fibroblast, ... |
### Question: Does vitamin B-complex application promote secondary palate development in a palate organ model of the A/WySnJ mouse? ### Context: This study analyzed the direct influence of vitamin B-complex supplements (Polybion N, Merck Pharma GmbH, Germany) in medium on secondary palatal development in palatal organ ... |
### Question: Can iterative reconstruction improve imaging quality for lower radiation CT perfusion? ### Context: Initial results using IR for CT of the head showed satisfactory subjective and objective imaging quality with a 20-40% radiation dose reduction. The aim of our study was to compare the influence of IR and F... |
### Question: Is the involvement of human amnion in histologic chorioamnionitis an indicator that a fetal and an intra-amniotic inflammatory response is more likely and severe : clinical implications? ### Context: Amnionitis (inflammation of the amnion) is the final stage of extra-placental chorioamniotic inflammation.... |
### Question: Does galectin-1 deficiency improve axonal swelling of motor neurones in SOD1 ( G93A ) transgenic mice? ### Context: Galectin-1, a member of the β-galactoside-binding lectin family, accumulates in neurofilamentous lesions in the spinal cords of both sporadic and familial amyotrophic lateral sclerosis (ALS)... |
### Question: Does [ Down-regulation of CT120A by RNA interference suppress lung cancer cells growth ]? ### Context: To validate our obtained outcomes and clarify the relationship between CT120A, a novel human plasma membrane-associated gene, and proliferation of lung cancer cells.A vector-based small hairpin RNA (shRN... |
### Question: Is the radio-sensitizing effect of xanthohumol mediated by STAT3 and EGFR suppression in doxorubicin-resistant MCF-7 human breast cancer cells? ### Context: Chemotherapeutic drug resistance remains a clinical obstacle in cancer management. Drug-resistant cancer cells usually exhibit cross-resistance to io... |
### Question: Is p300 amplitude insensitive to working memory load in schizophrenia? ### Context: Working memory (WM) tasks usually elicit a P300 ERP component, whose amplitude decreases with increasing WM load. So far, this effect has not been studied in schizophrenics (SZs), a group that is considered to have an aber... |
### Question: Is admission hyperglycaemia associated with higher mortality in patients with hip fracture? ### Context: To determine the proportion of hip-fracture patients with admission hyperglycaemia, and, when present, whether it was associated with a worse outcome (i.e. increased length of hospital stay, admission ... |
### Question: Are extreme urinary betaine losses in type 2 diabetes combined with bezafibrate treatment associated with losses of dimethylglycine and choline but not with increased losses of other osmolytes? ### Context: Betaine deficiency is a probable cardiovascular risk factor and a cause of elevated homocysteine. U... |
### Question: Does evidence suggest there was not a `` resurgence '' of kernicterus in the 1990s? ### Context: Although some have suggested that kernicterus disappeared in the United States in the 1970s to 1980s and dramatically reappeared in the 1990s, population-based data to support such a resurgence are lacking.We ... |
### Question: Does motor performance deteriorate with simultaneously performed cognitive tasks in geriatric patients? ### Context: To investigate whether simultaneous cognitive tasks influence maximal motor performance in frail geriatric patients with a history of injurious falls and different levels of cognitive funct... |
### Question: Do ingestion of casein and whey proteins result in muscle anabolism after resistance exercise? ### Context: Determination of the anabolic response to exercise and nutrition is important for individuals who may benefit from increased muscle mass. Intake of free amino acids after resistance exercise stimula... |
### Question: Does human acellular dermal matrix for ventral hernia repair reduce morbidity in transplant patients? ### Context: Organ transplantation is widely accepted as the treatment of choice for native organ failure. Due to required immunosuppression, however, organ recipients are prone to wound infections, incis... |
### Question: Is mRI-guided region-of-interest delineation comparable to manual delineation in dopamine transporter SPECT quantification in patients : a reproducibility study? ### Context: A particularly sensitive step in the quantification of SPECT images of the dopamine transporter (DAT) is a correct delineation of t... |
### Question: Does acute TSH stimulation in vivo alter serum PCSK9 levels? ### Context: It is now recognized that TSH can act on targets other than the thyroid, including the liver. Elevated serum TSH levels in euthyroid subjects were recently reported to correlate with high values of serum proprotein convertase subtil... |
### Question: Is c-index associated with functional outcomes after laparoscopic partial nephrectomy? ### Context: The C-index is a morphometric descriptor of renal masses that incorporates tumor size and site. We examined associations of the C-index with kidney function after laparoscopic partial nephrectomy.We retrosp... |
### Question: Is serum cystatin C a poor biomarker for diagnosing acute kidney injury in critically-ill children? ### Context: Accurate diagnosis of acute kidney injury (AKI) is problematic especially in critically-ill patients in whom renal function is in an unsteady state.Our aim was to evaluate the role of serum (S.... |
### Question: Do liver transplantation-induced antihistone H1 autoantibodies suppress mixed lymphocyte reaction? ### Context: In a rat model of orthotopic liver transplantation (OLT), recipient serum after OLT (post-OLT serum) has been reported to prevent allograft rejection. However, the molecular identities of immuno... |
### Question: Does clonidine inhibit anti-non-Gal IgM xenoantibody elicited in multiple pig-to-primate models? ### Context: Survival of vascularized xenografts is dependent on pre-emptive inhibition of the xenoantibody response against galactosyltransferase knockout (GTKO) porcine organs. Our analysis in multiple GTKO ... |
### Question: Are preoperative radiographic factors and surgeon experience associated with cortical breach of C2 pedicle screws? ### Context: A retrospective review study.In this study, we attempt to identify radiographic variables associated with likelihood of intraoperative breach during C2 pedicle screw placement. I... |
### Question: Is diabetic peripheral neuropathic pain a stronger predictor of depression than other diabetic complications and comorbidities? ### Context: To investigate the independent effect on depression of painless diabetic polyneuropathy, painful diabetic polyneuropathy, and general and diabetes-related comorbidit... |
### Question: Does the genotype of the transporter associated with antigen processing gene affect susceptibility to colorectal cancer in Japanese? ### Context: Although colorectal cancer (CRC) is one of the most frequent malignancies in Japan, the associated genetic factors remain to be elucidated. Functional loss of t... |
### Question: Does [ CTLA4-Ig interfere and downregulates the proinflammatory activities of rheumatoid synovial macrophages in monoculture ]? ### Context: CTLA4-Ig, a biologic agent employed in rheumatoid arthritis (RA) treatment, downregulates the immune response and exerts anti-inflammatory effects acting on differen... |
### Question: Are monitor units predictive of neutron dose for high-energy IMRT? ### Context: Due to the substantial increase in beam-on time of high energy intensity-modulated radiotherapy (>10 MV) techniques to deliver the same target dose compared to conventional treatment techniques, an increased dose of scatter ra... |
### Question: Is polymorphisms of GSTP1 associated with differences of chemotherapy response and toxicity in breast cancer? ### Context: Although chemotherapy is one of the most important treatments of breast cancer, it is limited by significant inter-individual variations in response and toxicity. The metabolism of ep... |
### Question: Can upfront systemic chemotherapy replace stereotactic radiosurgery or whole brain radiotherapy in the treatment of non-small cell lung cancer patients with asymptomatic brain metastases? ### Context: The optimal treatment for non-small cell lung cancer (NSCLC) patients with asymptomatic brain metastasis ... |
### Question: Does the glutathione depleting agent diethylmaleate prolong renal allograft survival? ### Context: Intercellular adhesion molecule 1 (ICAM-1) plays an important role in mediating allograft rejection through its role in cellular trafficking and as an important costimulatory signal mediating T cell activati... |
### Question: Do colorectal cancer cases and relatives of cases indicate similar willingness to receive and disclose genetic information? ### Context: Recent developments in genetic testing allow us to detect individuals with inherited susceptibility to some cancers. Genetic testing to identify carriers of cancer-relat... |
### Question: Are gastric precancerous lesions associated with gene variants in Helicobacter pylori-susceptible ethnic Malays? ### Context: To identify genes associated with gastric precancerous lesions in Helicobacter pylori (H. pylori)-susceptible ethnic Malays.Twenty-three Malay subjects with H. pylori infection and... |
### Question: Is 99mTc-phytate better than 99mTc-human serum albumin as a radioactive tracer for sentinel lymph node biopsy in breast cancer? ### Context: Several radioactive agents are used for sentinel lymph node biopsy (SLNB) in breast cancer, but we are still unsure which of these is best. We retrospectively compar... |
### Question: Is visfatin associated with inflammatory markers in patients on hemodialysis? ### Context: Cardiovascular events are a major cause of death in patients with end-stage renal disease. Endothelial dysfunction represents a key event in atherosclerosis development and has been implicated in the pathophysiology... |
### Question: Does dexamethasone protect neonatal hypoxic-ischemic brain injury via L-PGDS-dependent PGD2-DP1-pERK signaling pathway? ### Context: Glucocorticoids pretreatment confers protection against neonatal hypoxic-ischemic (HI) brain injury. However, the molecular mechanism remains poorly elucidated. We tested th... |
### Question: Does renal artery revascularization improve heart failure control in patients with atherosclerotic renal artery stenosis? ### Context: Renal artery stenosis (RAS) impacts the pathogenesis and control of heart failure (HF) and may further contribute to increased cardiovascular morbidity and mortality in HF... |
### Question: Does protease inhibitor therapy improve protein catabolism in prepubertal children with HIV infection? ### Context: Past studies in adults have reported that loss of lean tissue mass (LTM) is associated with accelerated rates of protein catabolism. To date, studies of protein kinetics from pediatric patie... |
### Question: Is anal human papillomavirus infection associated with HIV acquisition in men who have sex with men? ### Context: Human papillomavirus (HPV) is a common sexually transmitted agent that causes anogenital cancer and precancer lesions that have an inflammatory infiltrate, may be friable and bleed. Our aim wa... |
### Question: Is dyslipidemia in rat fed with high-fat diet associated with PCSK9-LDL-receptor pathway but ageing? ### Context: Obesity is associated with unfavorable alternations in plasma lipid profile and a broad spectrum of cardio-metabolic disorders. Proprotein convestase subtilisin kexin type 9 (PCSK9) is a novel... |
### Question: Social support among African Americans with heart failure: is there a role for community health advisors? ### Context: The study had 2 objectives: (1) to gather the observations of community health advisors (CHAs) on the role of social support in the lives of African Americans; and (2) to develop a lay su... |
### Question: Does the Z-cad dual fluorescent sensor detect dynamic changes between the epithelial and mesenchymal cellular states? ### Context: The epithelial to mesenchymal transition (EMT) has been implicated in metastasis and therapy resistance of carcinomas and can endow cancer cells with cancer stem cell (CSC) pr... |
### Question: Are alterations in plasma protease concentrations during labor associated with poor obstetric outcomes? ### Context: The purpose of this study was to assess the association between abnormal connective tissue remodeling during labor as reflected by plasma concentrations of extracellular matrix remodeling p... |
### Question: Does systolic blood pressure in childhood predict hypertension and metabolic syndrome later in life? ### Context: The goal was to link hypertension and the metabolic syndrome in adulthood directly to blood pressures measured decades earlier for the same individuals as children and to establish criterion v... |
### Question: Is there any relationship between plasma antioxidant capacity and lung function in smokers and in patients with chronic obstructive pulmonary disease? ### Context: It has been suggested that oxidative stress is an important factor in the pathogenesis of chronic obstructive pulmonary disease (COPD). We hav... |
### Question: Is overabundant FANCD2 , alone and combined with NQO1 , a sensitive marker of adverse prognosis in breast cancer? ### Context: Defective DNA repair is central to the progression and treatment of breast cancer. Immunohistochemically detected DNA repair markers may be good candidates for novel prognostic an... |
### Question: Is rotavirus-induced murine biliary atresia mediated by nuclear factor-kappaB? ### Context: Intraperitoneal inoculation of rhesus rotavirus (RRV) was shown to cause atretic-appearing segments of the extrahepatic bile ducts (EHBDs) in a murine model. The factors responsible for the injury of bile ducts, ho... |
### Question: Cogan I syndrome: too often detected too late? ### Context: Cogan's syndrome is an uncommon disease characterized by ocular inflammation, vestibuloauditory dysfunction and symptoms of systemic disease. The etiology is unknown, however there is evidence for an autoimmune pathogenesis. The "typical" Cogan's... |
### Question: Is the vasodilatory response of skin microcirculation to local heating subject to desensitization? ### Context: In humans, local heating increases skin perfusion by mechanisms dependent on nitric oxide (NO). Because the vascular effects of NO may be subject to desensitization, we examined whether a first ... |
### Question: Are nurse-facilitated preparation and life completion interventions acceptable and feasible in the Australian palliative care setting : results from a phase 2 trial? ### Context: Existential/spiritual needs of advanced cancer patients are not always met in healthcare. Potential barriers for health profess... |
### Question: Is jNK suppression essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells? ### Context: Epidemiological studies demonstrate that the incidence and mortality rates of colorectal cancer in women are lower than in men. Howev... |
### Question: Do psychiatric disorders and their association with burn-related factors in children with burn injury? ### Context: The aim of this study was to assess psychiatric disorders and their association with burn-related factors in a population of Turkish children with burns.Thirty-one children admitted to the C... |
### Question: Is low-molecular-weight heparin more effective than aspirin in preventing early neurologic deterioration and improving six-month outcome? ### Context: We evaluated the efficacy of low-molecular-weight heparin (LMWH) relative to aspirin in preventing early neurologic deterioration (END), venous thromboembo... |
### Question: Apical versus Non-Apical Lead: Is ICD Lead Position Important for Successful Defibrillation? ### Context: We aim to compare the acute and long-term success of defibrillation between non-apical and apical ICD lead position.The position of the ventricular lead was recorded by the implanting physician for 2,... |
### Question: Does symptom burden predict nursing home admissions among older adults? ### Context: Symptom burden has been associated with functional decline in community-dwelling older adults and may be responsive to interventions. Known predictors of nursing home (NH) admission are often nonmodifiable.To determine if... |
### Question: Does [ Eosinophilic esophagitis lead to dysphagia in a 18-year-old boy -- case report ]? ### Context: Eosinophilic esophsgitis (EE) is a chronic inflammatory disease of the esophagus which is characterized by isolated eosinophilic infiltrations within squamous esophageal epithelium and by macroscopic lesi... |
### Question: Is passive expiratory flow-volume curve an accurate method to measure the respiratory time constant in rabbits? ### Context: In mechanically ventilated patients, inspiration is forced by an externally applied positive pressure whereas expiration remains passive and depends on the time constant of the tota... |
### Question: Does false-positive meconium test result for fatty acid ethyl esters secondary to delayed sample collection? ### Context: Meconium analysis for fatty acid ethyl esters (FAEEs) is a validated method for identifying heavy prenatal ethanol (EtOH) exposure. This study investigated whether delayed sample colle... |
### Question: Is 17β Hydroxysteroid dehydrogenase type 12 ( HSD17B12 ) a marker of poor prognosis in ovarian carcinoma? ### Context: 17β-hydroxysteroid dehydrogenase isoform 12 (HSD17B12) overexpression is associated with poor clinical outcome in invasive ductal carcinoma of the breast. Here, we evaluated HSD17B12 over... |
### Question: Does melatonin reduce Cataract Formation and Aldose Reductase Activity in Lenses of Streptozotocin-induced Diabetic Rat? ### Context: The relationship between the high activity of aldose reductase (AR) and diabetic cataract formation has been previously investigated. The purpose of the present study was t... |
### Question: Does whole-body biodistribution and radiation dosimetry estimate for the PET dopamine transporter probe 18F-FECNT in non-human primates? ### Context: 2 beta-Carbomethoxy-3-(4-chlorophenyl)-8-(2-[18F]fluoroethyl)nortropane (18F-FECNT) is a selective radioligand for the in vivo quantification of dopamine tr... |
### Question: Is galectin-1 part of human trophoblast invasion machinery -- a functional study in vitro? ### Context: Interactions of glycoconjugates with endogenous galectins, have been long proposed to participate in several reproductive processes including implantation. In human placenta gal-1, gal-3, gal-8, and gal... |
### Question: Is 15 mm size criterion for lacunar infarction still valid? ### Context: The 'lacunar hypothesis' has been challenged, since small (diameter<15 mm) subcortical infarcts can be produced by middle cerebral artery disease (MCAD) or cardioembolism (CE), while a larger infarct can occur without evidence of MCA... |
### Question: Does hydrolysed protein accelerate the gastrointestinal transport of formula in preterm infants? ### Context: Vomiting, large gastric residuals and abdominal distension are common in very immature infants on formula feeding. The present trial investigated whether a protein hydrolysate formula reduces the ... |
### Question: Does helicobacter pylori tumor necrosis factor-α inducing protein promote cytokine expression via nuclear factor-κB? ### Context: To study the effects of Helicobacter pylori (H. pylori) tumor necrosis factor-α (TNF) inducing protein (Tip-α) on cytokine expression and its mechanism.We cloned Tip-α from the... |
### Question: Are macaca fascicularis highly susceptible to an RT-SHIV following intravaginal inoculation : a new model for microbicide evaluation? ### Context: Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) is a major target for antiretroviral strategy to block or curtail HIV infection. A suita... |
### Question: Does beta-adrenergic receptor 1 selective antagonism inhibit norepinephrine-mediated TNF-alpha downregulation in experimental liver cirrhosis? ### Context: Bacterial translocation is a frequent event in cirrhosis leading to an increased inflammatory response. Splanchnic adrenergic system hyperactivation h... |
### Question: Does the extent of prebending affect the stability of femoral shaft fractures stabilized by titanium elastic nails? ### Context: Elastic stable intramedullary nailing (ESIN) is a common procedure for stabilization of femoral shaft fractures in childhood. Prebending of the nail is generally recommended to ... |
### Question: Is 25-hydroxyvitamin D deficiency a risk factor for symptoms of postoperative hypocalcemia and secondary hyperparathyroidism after minimally invasive parathyroidectomy? ### Context: Patients with primary hyperparathyroidism who undergo minimally invasive parathyroidectomy (MIP) may have postoperative symp... |
### Question: Does triple combination therapy for hepatitis C with telaprevir exhibit greater early antiviral activity than with boceprevir? ### Context: Achievement of early viral suppression is important in patients with chronic HCV infection treated with telaprevir (TLV) or boceprevir (BOC) to avoid selection of dru... |
### Question: Is prolonged resuscitation of metabolic acidosis after trauma associated with more complications? ### Context: Optimal patterns for fluid management are controversial in the resuscitation of major trauma. Similarly, appropriate surgical timing is often unclear in orthopedic polytrauma. Early appropriate c... |
### Question: Is 18F-FDG uptake assessed by PET/CT in abdominal aortic aneurysms associated with cellular and molecular alterations prefacing wall deterioration and rupture? ### Context: Rupture of abdominal aortic aneurysms (AAAs) leads to a significant morbidity and mortality in aging populations, and its prediction ... |
### Question: Is the vitamin B12 analog cobinamide an effective hydrogen sulfide antidote in a lethal rabbit model? ### Context: Hydrogen sulfide (H2S) is a highly toxic gas for which no effective antidotes exist. It acts, at least in part, by binding to cytochrome c oxidase, causing cellular asphyxiation and anoxia. W... |
### Question: Do older adults prioritize postural stability in the anterior-posterior direction to regain balance following volitional lateral step? ### Context: Postural control in the medial-lateral (ML) direction is of particular interest regarding the assessment of changes in postural control, as it is highly relat... |
### Question: Is Two Really Better Than One? ### Context: Periprocedural stroke after carotid endarterectomy increases long-term mortality. Intraoperative monitoring with electroencephalography (EEG) and somatosensory-evoked potentials (SSEPs) helps predict perioperative stroke risk. However, the sensitivity of each te... |
### Question: Is ultrasonographic strain imaging superior to conventional non-invasive measures of vascular stiffness in the detection of age-dependent differences in the mechanical properties of the common carotid artery? ### Context: Elastic properties of large arteries have been shown to deteriorate with age and in ... |
### Question: Does melatonin reduce the expression of chemokines in rat with trinitrobenzene sulfonic acid-induced colitis? ### Context: To investigate the effect of melatonin on the colon inflammatory injury of rats with colitis and determine whether this effect is associated with inhibition of chemoattractant molecul... |
### Question: Do bioflavonoids attenuate renal proximal tubular cell injury during cold preservation in Euro-Collins and University of Wisconsin solutions? ### Context: Cold ischemia and reperfusion during kidney transplantation are associated with release of free oxygen radicals and damage of renal tubular cells. Biof... |
### Question: Recent trends of ophthalmic diseases in Italy: are official data reliable? ### Context: The aim of the study was to investigate the epidemiological trends of ocular diseases using hospital discharge forms as our data source.We examined official Italian Statistical Institute (ISTAT) data concerning patient... |
### Question: Does lamotrigine protect hippocampal CA1 neurons from ischemic damage after cardiac arrest? ### Context: Lamotrigine (LTG) is an anticonvulsant drug whose mechanism of action may involve the inhibition of glutamate release by blocking voltage-dependent sodium channels. Glutamate neurotoxicity may contribu... |
### Question: Customised birthweight percentiles: does adjusting for maternal characteristics matter? ### Context: The objective of this study was to determine whether the improved prediction of risk for perinatal mortality obtained with the use of a customised birthweight standard can also be obtained with the use of ... |
### Question: Is first-line eradication for Helicobacter pylori-positive gastritis by esomeprazole-based triple therapy influenced by CYP2C19 genotype? ### Context: To evaluate the effect of first line esomeprazole (EPZ)-based triple therapy on Helicobacter pylori (H. pylori) eradication.A total of 80 Japanese patients... |
### Question: Does Adenotonsillectomy really reduced clinic visits for pediatric upper respiratory tract infections? ### Context: To investigate whether adenotonsillectomy reduces upper respiratory tract infections (URIs) in the pediatric population.We identified 415 children, aged ≤18 years who had undergone adenoidec... |
### Question: Perforated peptic ulcer: is the form of methamphetamine known as "crystal meth" a new risk factor? ### Context: The emergence of new synthetic drugs related to peptic ulcer perforation has been reported. Recently an increase in the use of inhaled methamphetamine has been observed and we have described an ... |
### Question: Is severity of cough in idiopathic pulmonary fibrosis associated with MUC5 B genotype? ### Context: A polymorphism (rs35705950) in the promoter region of the mucin MUC5B is associated with both familial and sporadic forms of idiopathic pulmonary fibrosis. (IPF) We hypothesize that this common MUC5B varian... |
### Question: Delayed-Type Hypersensitivity to Metals of Environmental Burden in Patients with Takotsubo Syndrome - Is There a Clinical Relevance? ### Context: Takotsubo syndrome (TS) is a heart condition characterised by a sudden transient left ventricular dysfunction; its pathophysiology is probably associated with e... |
### Question: Depression and cardiovascular mortality: a role for n-3 fatty acids? ### Context: Recent studies indicate that depression plays an important role in the occurrence of cardiovascular diseases (CVDs). The underlying mechanisms are not well understood.We investigated whether dietary intake of the n-3 fatty a... |
### Question: Do adverse rearing experiences enhance responding to both aversive and rewarding stimuli in juvenile rhesus monkeys? ### Context: While adverse rearing is thought to alter threat responding, the effects on appetitive behavior remains minimally explored. This study examines the effects that early life emot... |
### Question: Does interval training attenuate the metabolic disturbances in type 1 diabetes rat model? ### Context: This study investigated the effect of interval training on blood biochemistry and immune parameters in type 1 diabetic rats.Male Wistar rats were divided into four groups: sedentary (SE, n = 15), interva... |
### Question: Is liposome-encapsulated hemoglobin ( hemoglobin-vesicle ) transferred from mother to fetus at the late stage of pregnancy in the rat model? ### Context: Liposome-encapsulated hemoglobin (hemoglobin vesicles: HbV; diameter 250 nm) is reconstructed from human hemoglobin and developed as an artificial oxyge... |
### Question: Does somatostatin receptor type 2 contribute to the self-renewal of murine embryonic stem cells? ### Context: The roles of G-protein coupled receptors (GPCRs) in stem cell biology remain unclear. In this study, we aimed to identify GPCRs that might contribute to the self-renewal of mouse embryonic stem ce... |
### Question: Does awarding a medical degree with honours act as a motivator or demotivator to student learning? ### Context: To look at students' support for, and perception of, the effects of awarding a degree with honours.Questionnaires were given to all medical students from those entering year 1 to those graduatin... |
### Question: Does twenty Questions game performance on medical school entrance predict clinical performance? ### Context: This study is based on the premise that the game of 'Twenty Questions' (TQ) tests the knowledge people acquire through their lives and how well they organise and store it so that they can effective... |
### Question: Are the daily diary and the questionnaire equivalent for the evaluation of bowel habits? ### Context: It is unclear whether questionnaires and diary cards, which are widely used to collect data on bowel habits, provide analogous information.We verified the concordance between the data provided by a daily ... |
### Question: Do a mixture of feature experts approach for protein-protein interaction prediction? ### Context: High-throughput methods can directly detect the set of interacting proteins in model species but the results are often incomplete and exhibit high false positive and false negative rates. A number of research... |
### Question: Does the external rotation immobilisation reduce recurrence rates or improve quality of life after primary anterior shoulder dislocation : a systematic review and meta-analysis? ### Context: Conducting a systematic review and meta-analysis of prospective randomised controlled trials directly comparing (1)... |
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