term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tetrapyrrole binding | 8 | 15 | 2.077341 | 0.03777 | Q9H7Z7,Q6UW02,O00264,Q9NRV9,Q7KZN9,P30519,O43169,Q16850 | Functions | GO Molecular function | msigdb_gomf | 387,72,237,505,465,21,91,63 | 237,91,1569,1007,1573,21,2557,63,72,465,1494,1136,504,387,505 | 1.3901468727742385,2.2578686584330105,-0.11220249635179408,0.27291968269656813,-0.11220249635179408,3.319944621755534,-0.7485248627310643,2.495900762472715,2.4015403846490684,0.8737472783538901,-0.06295244245028012,0.17849600673831648,0.8157706641011584,1.0309426134342197,0.8157706641011584 | 3,120 |
Translocation | 17 | 47 | 2.071052 | 0.038354 | Q9BTX1,Q9Y5J9,Q3ZCQ8,Q9NS69,O60830,P12270,P57740,Q15629,Q7Z3B4,O14925,O43615,P55735,Q99567,Q8TD16,P37198,O75381,Q8N1F7 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 546,461,329,77,14,400,304,561,308,149,584,438,538,118,499,219,190 | 2951,149,584,14,219,1338,400,685,499,2509,2417,1084,1216,438,304,3068,2956,3025,2487,951,561,329,2471,1746,308,190,1443,642,994,118,1391,1093,2650,1900,1556,2401,538,546,1497,1998,1875,77,1138,1423,2432,461,2071 | -1.3090459546983426,1.8104905344165125,0.6836796028570836,3.662148863096418,1.4573445331488604,0.03457322912919779,1.0026016209135598,0.5642956462857995,0.8157706641011584,-0.7126680845484551,-0.6414835578447224,0.21010374774524396,0.11487460343449528,0.9169413951198621,1.2126438954569019,-1.7709185436163724,-1.3090459... | 3,120 |
Alzheimers disease | 26 | 59 | 2.065639 | 0.038863 | P00846,P24539,P22695,P14406,Q00535,P00403,P25705,P06576,P27361,P20674,O95168,O14949,O96000,P16615,P49841,O75947,Q99653,P21912,Q9UDW1,P13073,O14548,O95169,Q9Y6M9,P36542,P14927,O75489 | Processes and pathways | KEGG Pathways | msigdb_kegg | 7,523,401,19,154,276,533,156,551,684,555,58,65,444,702,570,330,717,93,98,479,609,632,624,249,738 | 3093,2410,479,58,2930,1336,2803,878,1758,738,570,555,609,1677,2204,65,276,7,3013,156,2300,1569,1428,1711,98,19,1618,249,1312,444,2443,2182,684,717,401,523,533,551,2207,1407,2381,2302,624,1654,2105,2261,3036,702,2304,154,1835,1147,1947,773,330,1752,93,2653,632 | -2.243291875020247,-0.6414835578447224,0.8448142839802352,2.51931754717366,-1.2509707594161343,0.03457322912919779,-1.0232974504893133,0.38159146097785057,-0.2284164650375626,0.5038867309618552,0.6984707313156334,0.7132329833227257,0.6540102092830856,-0.17838548918434077,-0.5011773922472554,2.44886013744723,1.308730272... | 3,120 |
Lower limb muscle weakness | 14 | 44 | 2.059116 | 0.039483 | O43819,O95140,P00846,Q9Y4W6,Q9NR77,Q13510,Q8N0X7,P07196,P06753,P02545,P37198,O75298,Q92734,Q15120 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 514,481,7,211,85,440,537,22,220,119,499,188,580,511 | 1121,514,188,729,481,7,119,1026,220,22,2300,1545,2257,1794,2575,499,2383,2282,2769,1433,2018,2644,2108,2723,1865,1628,440,2243,575,2489,511,1036,2334,651,1492,537,1840,580,735,1633,1250,85,211,1478 | 0.17849600673831648,0.786615468427979,1.5900158562501612,0.5190345053695938,0.8448142839802352,3.813122404253874,2.01246909431283,0.2572652505088006,1.443951626246411,3.30934871430298,-0.570991623394744,-0.09574924303379817,-0.5360007060205642,-0.24516947172325332,-0.766520239175899,0.8157706641011584,-0.62379623391370... | 3,120 |
Protein transmembrane import into intracellular organelle | 6 | 12 | 2.054536 | 0.039924 | Q3ZCQ8,O60830,O14925,O95831,O75381,Q15388 | Processes and pathways | GO Biological process | msigdb_gobp | 329,14,149,24,219,485 | 149,584,1511,14,219,1426,24,912,1545,485,329,1229 | 1.8104905344165125,0.6836796028570836,-0.07933261901370642,3.662148863096418,1.4573445331488604,-0.030300711303461843,3.2454831822206605,0.35070324111746226,-0.09574924303379817,0.8448142839802352,1.1432677072413866,0.11487460343449528 | 3,120 |
Abnormal exteroceptive sensation | 7 | 47 | 2.052953 | 0.040077 | P54802,Q8NCH0,Q9NZ08,Q9NR77,P07196,O95831,Q9H6K4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 242,99,176,85,22,24,121 | 1060,764,2153,2552,481,2503,24,557,1732,1026,2233,1285,22,2011,2181,2531,1828,2257,2104,1987,2381,855,1082,2261,1966,2699,1085,242,1433,2018,2140,2809,255,2723,1865,837,2060,2490,99,1170,2312,121,85,176,1401,2041,1478 | 0.2258574389042269,0.48870836441780346,-0.46651989752259204,-0.7485248627310643,0.8448142839802352,-0.7126680845484551,3.2454831822206605,0.7132329833227257,-0.21170159451326637,0.2572652505088006,-0.5185682109135206,0.06679822788517814,3.30934871430298,-0.3805901708428884,-0.483828027884879,-0.7305742271780316,-0.2619... | 3,120 |
Talipes equinovarus | 28 | 80 | 2.051004 | 0.040267 | P61978,P36543,Q15907,Q96AY3,Q9NWM8,Q15392,Q5H8A4,Q03001,Q8NI60,Q8TAA9,P16435,P08236,Q9NR77,Q7RTS9,Q9H6U8,Q9Y487,Q96A33,Q96L58,P06753,Q9UJX6,Q9H9E3,Q8NCH0,P21964,Q6NUQ1,O96028,Q8TD16,P98175,Q01082 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 255,373,138,271,32,296,577,573,457,325,454,205,85,87,605,88,347,348,220,619,489,99,355,379,622,118,376,639 | 2319,932,2348,1511,2179,933,2622,2202,1238,1340,964,622,1026,220,205,3089,454,2257,2674,355,1407,373,1432,2159,1125,866,1126,1918,2326,1433,255,376,639,1626,573,1865,2451,1802,296,733,138,577,379,1720,1529,87,803,99,1365,1840,457,325,1444,118,2473,1152,1633,347,271,348,2337,653,1997,1498,605,2873,489,2091,1002,85,32,61... | -0.5885504992892956,0.3352111717576097,-0.606151958922442,-0.07933261901370642,-0.483828027884879,0.3352111717576097,-0.8207773259856875,-0.5011773922472554,0.09888373702173922,0.03457322912919779,0.30413037071405097,0.6391316883481546,0.2572652505088006,1.443951626246411,1.5106857256113622,-2.133064880472113,0.8881725... | 3,120 |
Abnormal lower motor neuron morphology | 6 | 9 | 2.044906 | 0.040864 | Q99720,Q13501,P35637,Q13510,P43243,Q9UQN3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 102,552,174,440,500,582 | 174,500,2018,1409,552,440,575,102,582 | 1.6424561771136268,0.8157706641011584,-0.3805901708428884,-0.014028799969153467,0.7279664846318218,0.9169413951198621,0.6984707313156334,2.1483809702874805,0.6984707313156334 | 3,120 |
Protein kinase | 23 | 69 | 2.031875 | 0.042166 | P06493,P49840,Q99640,Q96KB5,Q9Y6K9,O75116,Q00536,Q9P289,P50750,Q00535,P24941,P27361,P54646,P51812,Q13464,O75962,P31751,Q7KZI7,Q13555,Q13557,Q16513,Q15120,Q15418 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 129,131,654,652,529,521,18,542,151,154,31,551,423,172,189,203,206,472,356,493,626,511,127 | 1457,815,2795,816,2348,1205,521,203,1823,2047,1883,129,983,1287,1916,2135,31,551,1407,206,1796,2353,1547,1766,2054,1738,131,702,2907,151,172,2284,1294,423,1520,2559,154,18,2645,1864,1218,1361,1550,189,2082,969,356,493,922,511,784,671,127,626,1552,2886,472,1928,2473,652,2248,654,2802,1224,1672,1160,542,2174,529 | -0.046608532900190375,0.44298832212023614,-1.0046484114833856,0.44298832212023614,-0.606151958922442,0.11487460343449528,0.7719957292272027,1.523963856715977,-0.2619608096795884,-0.3976953730192357,-0.2956592676299645,1.9499071826655876,0.2885413384136224,0.06679822788517814,-0.312566785682029,-0.44925278266923796,3.10... | 3,120 |
Response to toxic substance | 11 | 48 | 2.028672 | 0.042492 | P06493,P00374,P07099,O43464,Q9Y2Q3,P08183,P07196,Q13242,O95831,Q15165,Q86WA6 | Processes and pathways | GO Biological process | msigdb_gobp | 129,354,44,389,302,116,22,183,24,27,92 | 1708,2297,389,2712,1646,24,354,1240,1568,1101,129,44,22,116,1963,3038,2301,2849,3059,2183,2837,2914,2808,1515,2484,767,409,2209,989,732,919,183,1382,27,2333,1893,1298,897,92,2816,1601,1392,1780,3083,2457,2496,1198,302 | -0.1950246665788902,-0.570991623394744,1.0167852644421618,-0.9121244013006663,-0.16178387178475653,3.2454831822206605,1.0732579772137116,0.09888373702173922,-0.11220249635179408,0.1943166566085935,1.9499071826655876,2.7838025090073337,3.30934871430298,2.0373552452822294,-0.34649940710130533,-1.5865550545342373,-0.57099... | 3,120 |
Abnormality of the calf | 12 | 58 | 2.025866 | 0.042779 | Q7LGA3,Q9NX62,Q32P28,Q13126,P08236,Q9NR77,Q7RTS9,O95831,Q96L58,O75718,P16278,O75431 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 4,168,139,112,205,85,87,24,348,241,315,313 | 2319,2098,1122,2622,313,241,2253,24,1883,1732,205,2322,315,454,1287,2674,2575,2483,2927,1797,2353,1344,2159,1291,1833,639,2141,2645,732,1595,112,2211,576,733,1597,139,4,87,2472,537,1365,2473,381,348,2337,1997,1697,2498,85,1056,1753,1329,168,2781,1816,2318,1279,1334 | -0.5885504992892956,-0.4320264666261241,0.17849600673831648,-0.8207773259856875,1.1849686248979059,1.37663694769063,-0.5360007060205642,3.2454831822206605,-0.2956592676299645,-0.21170159451326637,1.5106857256113622,-0.5885504992892956,1.1849686248979059,0.8881725845149391,0.06679822788517814,-0.8754462172552409,-0.7665... | 3,120 |
Intermediate filament | 8 | 20 | 2.01326 | 0.044087 | Q16352,P07197,P20700,P08670,P07196,Q03252,P02545,O75298 | Localization | GO Cellular component | msigdb_gocc | 66,105,231,16,22,182,119,188 | 2127,188,119,22,105,16,2696,2638,231,290,2054,1941,1166,573,182,1036,66,1396,1561,661 | -0.44925278266923796,1.5900158562501612,2.01246909431283,3.30934871430298,2.1238431973235943,3.570223146966479,-0.8937619071209996,-0.8389541891155845,1.4036332115706927,1.2676972286857384,-0.3976953730192357,-0.3295134311551762,0.14675338988725495,0.6984707313156334,1.6162802105485474,0.2572652505088006,2.448860137447... | 3,120 |
Microbody | 10 | 52 | 2.003159 | 0.04516 | P51648,Q8N4Q0,Q15067,P52758,Q9Y2Q3,P08670,Q9NR77,O75381,Q13011,A8MXV4 | Localization | GO Cellular component | msigdb_gocc | 132,5,328,332,302,16,85,219,28,155 | 155,979,909,1281,831,2007,1511,1881,219,1162,2482,2101,730,16,2925,984,1618,966,2157,2913,2808,2078,1431,2353,437,1066,132,1126,332,2677,1595,28,3017,328,2581,1894,824,1806,1896,5,803,1444,1170,707,2118,350,604,513,85,2589,2827,302 | 1.772033110463191,0.2885413384136224,0.35070324111746226,0.06679822788517814,0.42768619226574317,-0.3805901708428884,-0.07933261901370642,-0.2956592676299645,1.4573445331488604,0.14675338988725495,-0.6948061890014895,-0.4320264666261241,0.5190345053695938,3.570223146966479,-1.231717470627754,0.2885413384136224,-0.14521... | 3,120 |
Regulation of rna splicing | 28 | 86 | 1.998329 | 0.045681 | Q9UHX1,P61978,P52597,P52756,P31942,Q9Y580,Q9Y2W1,P98179,P35637,Q07666,P31943,Q13242,O75494,Q14011,P22626,Q13243,P62995,Q13595,Q9BWF3,Q12849,P38159,Q16629,Q07021,P55795,Q15007,Q5BKZ1,Q07955,P98175 | Processes and pathways | GO Biological process | msigdb_gobp | 388,255,254,406,153,288,549,36,174,439,307,183,554,56,193,590,213,226,360,613,103,357,233,232,494,366,243,376 | 1456,910,1122,554,1062,1006,1008,914,2442,2014,2102,854,193,1939,1104,1795,2914,1517,153,307,174,103,1577,1345,667,625,254,406,1216,2643,232,255,2629,213,1437,376,36,2724,2755,233,439,243,1521,2450,1921,613,2662,183,590,859,839,226,56,1524,2421,494,1323,733,992,357,1719,2964,366,884,2168,1579,2089,1691,1692,1366,927,99... | -0.046608532900190375,0.35070324111746226,0.17849600673831648,0.7132329833227257,0.2258574389042269,0.27291968269656813,0.27291968269656813,0.35070324111746226,-0.6592141662818555,-0.3805901708428884,-0.4320264666261241,0.4123527679415628,1.5768503245839907,-0.3295134311551762,0.1943166566085935,-0.24516947172325332,-1... | 3,120 |
EF-Hand 1, calcium-binding site [IPR018247] | 10 | 35 | 1.986375 | 0.046992 | Q9NWM8,P80303,Q9BPX6,Q13813,O43852,Q96D71,Q15293,Q14257,Q9BRK5,Q02818 | Sequence | InterPro Binding site | interpro_binding_site | 32,3,67,227,70,230,265,9,246,30 | 569,70,888,982,964,2300,585,3070,666,2443,1886,1620,2838,2509,1462,987,3,30,573,227,9,2541,265,1386,1897,271,230,67,246,1073,618,32,2346,442,661 | 0.6984707313156334,2.41339669379397,0.3661632883154021,0.2885413384136224,0.30413037071405097,-0.570991623394744,0.6836796028570836,-1.791706727074942,0.5793224179068317,-0.6592141662818555,-0.2956592676299645,-0.14521962532452135,-1.079538114927136,-0.7126680845484551,-0.046608532900190375,0.2885413384136224,3.9122657... | 3,120 |
Receptor | 19 | 38 | 1.977059 | 0.048035 | P06493,O15118,P10586,P24390,Q9Y2W1,P30825,Q9Y5M8,Q8WTV0,Q9Y2I1,P35613,Q9NS69,Q93034,Q99720,Q9UBG0,Q99623,O00264,O15031,Q14108,P20645 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 129,253,633,10,549,35,294,61,596,201,77,335,102,372,630,237,498,378,509 | 237,2127,498,253,2573,819,1341,129,1064,2530,1915,1028,633,3105,1029,1618,509,10,35,201,1655,1550,378,2359,2389,671,1468,2944,61,335,630,102,77,372,596,549,294,2689 | 1.3901468727742385,-0.44925278266923796,0.8157706641011584,1.3495459683507376,-0.766520239175899,0.44298832212023614,0.03457322912919779,1.9499071826655876,0.2258574389042269,-0.7305742271780316,-0.312566785682029,0.2572652505088006,0.6242237793066672,-2.515301632905819,0.2572652505088006,-0.14521962532452135,0.8012070... | 3,120 |
Calcium ion binding | 28 | 80 | 1.969744 | 0.048868 | P80303,P55327,Q14257,Q15293,Q8IYU8,Q96AY3,Q9UPN3,Q02818,Q9NWM8,O43681,Q9UBV8,O60476,P16615,Q9BPX6,Q03001,O43852,O43707,Q99653,P12814,Q96A33,Q9UJS0,Q9H4M9,P67936,Q13813,Q96D71,Q9BRK5,Q9UM22,Q99584 | Functions | GO Molecular function | msigdb_gomf | 3,524,9,265,145,271,661,30,32,665,442,64,444,67,573,70,569,330,585,347,490,618,225,227,230,246,506,252 | 961,2177,665,569,70,64,888,2846,982,1731,964,1856,1427,1050,2300,1182,1589,1793,585,1678,3070,666,798,444,2443,2103,1886,891,2104,1343,2913,1620,2838,3100,2509,1462,987,1680,1830,524,1242,2306,781,225,3,30,573,2358,227,2359,1741,9,2541,265,749,1386,1090,1897,145,804,347,271,1447,230,252,330,998,67,246,1095,1073,618,32,... | 0.30413037071405097,-0.483828027884879,0.5793224179068317,0.6984707313156334,2.41339669379397,2.47241511073889,0.3661632883154021,-1.0983838132255241,0.2885413384136224,-0.21170159451326637,0.30413037071405097,-0.2787906755702021,-0.030300711303461843,0.24157788767834681,-0.570991623394744,0.13083109947309807,-0.128692... | 3,120 |
Neurogenesis | 17 | 44 | 1.964234 | 0.049503 | Q15375,Q8IXJ6,Q16352,P49840,P48681,P16949,P49841,Q96EK5,P55209,Q9UJX6,Q8TAQ2,Q13555,Q16643,Q16637,Q9BVA1,Q9NQC3,Q00535 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 671,33,66,131,290,289,702,458,40,619,562,356,650,627,564,282,154 | 2373,1936,2127,1731,2180,2877,289,1106,2961,290,131,702,1464,40,2995,154,1628,356,1194,671,66,2787,627,650,1871,1951,33,562,1300,1325,1446,735,458,1808,1415,957,1901,564,2295,282,619,1933,864,1425 | -0.623796233913705,-0.3295134311551762,-0.44925278266923796,-0.21170159451326637,-0.483828027884879,-1.1552214493474031,1.2676972286857384,0.1943166566085935,-1.328510537079896,1.2676972286857384,1.9373348286481238,0.5492388269345314,-0.046608532900190375,2.8849739127891,-1.426644682165865,1.7848732800962697,-0.1452196... | 3,120 |
Transition metal ion transmembrane transporter activity | 6 | 7 | 1.962882 | 0.04966 | Q15043,Q04656,Q8N4V1,Q9HD20,Q8TAD4,P98194 | Functions | GO Molecular function | msigdb_gomf | 417,732,120,55,448,446 | 767,446,732,417,120,448,55 | 0.48870836441780346,0.902570585002106,0.5190345053695938,0.9598918250269893,2.01246909431283,0.902570585002106,2.60074042050876 | 3,120 |
oxidase | 9 | 15 | 1.961404 | 0.049832 | P13073,O43819,O14548,O75880,Q15800,Q8NB78,P14406,Q6ZRP7,P36551 | Functions | Panther Protein class | panther_protein_class | 98,514,479,608,495,367,19,464,409 | 479,514,1646,1238,608,1711,98,19,1312,684,409,1186,495,464,367 | 0.8448142839802352,0.786615468427979,-0.16178387178475653,0.09888373702173922,0.6540102092830856,-0.1950246665788902,2.172842799903386,3.4042217306899554,0.05070324943423878,0.5642956462857995,0.9741550117257047,0.13083109947309807,0.8303063613261049,0.8737472783538901,1.0591788621121219 | 3,120 |
Regulation of response to external stimulus | 12 | 122 | 2.734303 | 0.006251 | P58107,P28070,P04792,P80303,P19474,Q9UMX5,P46108,P39019,Q9NZ08,Q9UIV1,P04083,O75844 | Processes and pathways | GO Biological process | msigdb_gobp | 131,38,8,9,134,12,109,141,53,117,157,29 | 1310,2332,3039,2614,165,1455,736,1356,2338,2089,2584,29,1164,1508,864,1680,2886,572,1073,157,675,8,676,825,796,1514,2670,1981,1836,3028,1277,1632,134,2153,1166,1733,624,522,2241,38,1571,1316,709,141,1281,1171,109,2099,1945,1644,2934,1420,1849,2700,131,500,479,2208,2982,1284,9,983,2386,2432,1585,419,2508,1948,2864,1332,... | 0.05277724123249238,-0.4886907650108802,-1.730504704367708,-0.7111216633283606,1.4518288819205634,-0.027189200602383484,0.4464720841136712,0.026168823056108712,-0.4886907650108802,-0.35142802015740865,-0.6831229298512316,3.175721357920611,0.1323238448236439,-0.053939439369814705,0.3424571699660142,-0.13447894173462346,... | 3,120 |
Cell cycle checkpoints | 45 | 131 | 2.684046 | 0.007274 | P15927,Q8NFH3,P62805,P27348,P49721,Q8NBT2,Q12888,Q96EE3,Q9UQ84,Q16537,O00231,P61981,Q99436,Q13257,P28070,P61088,P62258,P28072,P16104,P17980,P55735,Q9UL46,Q9UJX5,P30154,Q9HBM1,P20618,Q9Y6G9,Q06323,Q9Y266,P49736,P25787,P63104,Q14566,P33993,Q9NQS7,P51530,P49720,Q15691,Q96DE5,Q16763,Q9UJX6,P28074,O43237,O60934,P60900 | Processes and pathways | Reactome Pathways | msigdb_reactome | 622,663,389,388,14,275,659,410,152,285,398,527,424,162,38,293,418,45,546,679,682,596,198,449,81,79,350,579,477,712,340,714,602,710,759,229,228,748,509,365,515,114,614,617,500 | 2331,398,1777,1268,860,2665,614,1354,1272,1975,1312,1506,2235,617,2338,1930,2422,823,2377,1834,1043,622,546,679,79,3041,1635,1733,340,1470,2554,388,979,1570,38,45,114,743,449,1229,798,1359,1984,710,1892,1168,1737,940,3001,1641,2202,2912,2878,1940,1740,1577,228,14,712,1363,1088,229,942,1689,1645,1234,682,1898,500,293,94... | -0.4886907650108802,0.8306205699214327,-0.18841590743374792,0.07933901308957453,0.3424571699660142,-0.7672904390774098,0.5498089309100204,0.026168823056108712,0.07933901308957453,-0.2968876269475981,0.05277724123249238,-0.053939439369814705,-0.43362747907180343,0.5498089309100204,-0.4886907650108802,-0.2696941004659042... | 3,120 |
Lipid binding | 29 | 133 | 2.603624 | 0.009224 | Q9UNZ2,A6NIH7,P07355,Q9NZD2,Q9BWH2,P21796,Q9Y3E7,Q8WTV0,P04083,O95772,O15118,P45880,Q14677,P28070,O00264,Q9UM22,Q8NCC3,P11182,O14773,P09525,Q14108,Q15075,P50897,Q13045,Q99623,O60749,Q9Y2I1,Q99584,Q9NQZ5 | Functions | GO Molecular function | msigdb_gomf | 265,133,387,145,277,19,153,149,157,30,399,32,420,38,415,170,57,60,68,317,84,212,87,355,106,225,245,113,122 | 1265,133,415,1310,2812,2945,1926,68,1311,1622,399,2333,1884,2419,427,615,225,1355,1677,2850,1221,620,30,1073,157,1935,387,2887,1511,796,317,1515,740,2463,60,1165,1630,1408,707,2154,19,1569,1732,1733,38,1638,1517,708,2345,1085,2981,1415,1473,32,576,1642,1230,87,1523,1283,2958,1478,831,2104,3063,2978,3080,2959,872,873,26... | 0.07933901308957453,1.621858891133288,0.8052905536644204,0.05277724123249238,-0.9657274240742659,-1.2252896407485798,-0.26969410046590425,2.3098628465139983,0.05277724123249238,-0.10758398197060996,0.8306205699214327,-0.4886907650108802,-0.24255120737178565,-0.5439685899054248,0.7799215713822935,0.5498089309100204,1.20... | 3,120 |
Mitotic metaphase and anaphase | 42 | 135 | 2.505699 | 0.012221 | Q8NFH3,P49721,Q8NBT2,Q96EE3,Q9Y3E7,Q16537,O00231,P42166,Q99436,Q13257,Q7Z5K2,P28070,P20700,Q9UQN3,P28072,Q8N1F7,P17980,P55735,Q9UL46,P42167,Q9UJX5,P30154,Q9HBM1,P20618,Q9Y6G9,Q06323,P02545,Q9Y266,P50402,Q8NC56,P25787,Q9NQS7,Q9UN37,P49720,Q15691,Q96DE5,Q16763,Q9UJX6,P28074,P30153,O43237,P60900 | Processes and pathways | Reactome Pathways | msigdb_reactome | 663,14,275,410,153,285,398,155,424,162,557,38,416,179,45,176,679,682,596,192,198,449,81,79,350,579,703,477,469,91,340,759,761,228,748,509,365,515,114,743,614,500 | 2331,398,1777,1268,860,2665,614,1354,1272,1975,2195,1506,2338,2089,1678,1930,703,1934,1834,1043,679,1786,79,416,1733,340,1470,2554,1570,38,45,114,743,449,1229,940,1415,155,192,2912,2878,1940,1740,1577,228,14,1363,469,942,1689,1645,801,1234,682,1898,500,944,771,1239,1174,2106,802,2959,2049,579,2053,2165,162,2210,1244,21... | -0.4886907650108802,0.8306205699214327,-0.18841590743374792,0.07933901308957453,0.3424571699660142,-0.7672904390774098,0.5498089309100204,0.026168823056108712,0.07933901308957453,-0.2968876269475981,-0.40617531202550544,-0.053939439369814705,-0.4886907650108802,-0.35142802015740865,-0.13447894173462346,-0.2696941004659... | 3,120 |
Vacuole | 38 | 210 | 2.287306 | 0.022178 | Q15165,Q9NRR5,Q9Y6I9,P42785,P42892,P19474,P08236,Q16625,Q8TBX8,Q9Y3E7,Q8WTV0,Q13217,O95772,Q13501,Q07065,P17900,Q9UM22,Q9UQN3,Q13510,P20645,Q9UHG3,P78537,P36543,Q8NCC3,O15260,Q969Q5,O14773,Q8NHP8,P11117,O95721,Q14108,P50897,P41440,Q9UHD9,Q96A57,Q9UIQ6,O60749,O75503 | Localization | GO Cellular component | msigdb_gocc | 1,132,266,7,135,134,258,143,144,153,149,156,30,164,36,167,170,179,49,173,55,54,182,57,59,66,68,196,73,82,84,87,88,219,217,97,225,247 | 2084,1114,2945,2664,2928,68,1311,399,59,351,614,1274,1455,862,225,1355,1677,2615,647,247,739,2284,620,82,30,2421,2976,2719,2886,386,1073,2288,767,1225,2773,387,1729,936,2644,676,1511,704,258,825,2589,705,1888,1937,447,73,740,2149,2670,3085,495,2093,1315,167,134,173,1684,361,374,1633,2911,2241,1571,1228,292,798,799,182,... | -0.35142802015740865,0.15874750948681826,-1.2252896407485798,-0.7672904390774098,-1.1961930755430128,2.3098628465139983,0.05277724123249238,0.8306205699214327,2.37961945865008,0.9315554467942064,0.5498089309100204,0.07933901308957453,-0.027189200602383484,0.3424571699660142,1.2060429167815752,0.026168823056108712,-0.13... | 3,120 |
Transporter activity | 38 | 167 | 1.976466 | 0.048102 | P36542,P00846,Q8TDW0,P07355,Q8IXU6,Q9NZD2,P21796,Q8WTV0,P13073,P20020,Q9UDW1,O15118,P45880,O14925,P17900,Q9Y277,Q9H2D1,Q9Y6M9,P20674,P36543,Q8N4V1,O75947,P08183,Q6N075,P24539,O96000,P41440,O43772,O75964,Q9NS69,Q9BQT8,O14548,Q14847,Q9P0J0,P56385,P21281,O60830,P21283 | Functions | GO Molecular function | msigdb_gomf | 376,129,393,387,17,145,19,149,23,402,28,399,32,280,167,42,46,312,302,182,188,313,191,64,70,315,88,216,96,224,235,103,231,371,363,361,118,374 | 2492,3072,1353,1620,103,821,280,399,3027,1274,216,1162,1118,118,1403,2931,2196,2996,1070,619,313,96,1508,1461,2339,795,1462,2666,2090,315,1978,702,129,2877,1073,1935,650,2586,493,1784,387,1511,191,704,1076,3087,2294,865,2499,2617,23,1009,167,2037,402,302,361,374,19,1569,2155,70,1637,2646,1279,2345,523,2527,1086,376,182... | -0.599464148210851,-2.037861395393652,0.026168823056108712,-0.10758398197060996,1.8620039838746683,0.3685253915240254,1.0818260740115273,0.8306205699214327,-1.6097572775100977,0.07933901308957453,1.2554789753288864,0.1323238448236439,0.15874750948681826,1.742328421691365,-0.0004865526214166729,-1.1961930755430128,-0.40... | 3,120 |
Lysosome | 20 | 46 | 4.452133 | 0.000009 | P54802,Q9Y487,Q8NCC3,P04066,O75503,P11117,Q13510,P20645,P50897,P10619,Q15904,P17900,O14773,Q14108,O15118,Q93050,P11717,P06280,P15586,P08236 | Processes and pathways | KEGG Pathways | msigdb_kegg | 264,150,21,282,27,41,44,46,51,58,186,190,66,67,95,99,233,232,111,247 | 1859,3072,66,95,1768,2089,27,1773,282,232,400,829,247,655,1714,2429,58,41,2149,233,1484,111,283,190,46,486,51,2707,264,2163,3065,1933,1401,44,67,186,21,2318,99,902,2372,1763,1061,549,1517,150 | -0.23617802356071166,-2.1110040441905302,2.385428384194839,2.0329969890041335,-0.17996198897025922,-0.37966711166030426,3.44643436310832,-0.17996198897025922,1.0880085580638097,1.2353427068536198,0.8466959209611702,0.39833990773856,1.172767077784285,0.5445741216866079,-0.15209923198018688,-0.5880217491572218,2.51285660... | 3,120 |
Vacuolar membrane | 25 | 114 | 4.006631 | 0.000062 | Q9UQN3,P42785,Q9Y487,O75503,Q8WTV0,Q9UIQ6,O15260,Q8IV08,Q07065,P11117,P42892,P20645,O95772,P10619,Q14108,O95721,P41440,Q9Y3E7,P36543,O15118,O15400,Q93050,Q9Y6I9,P78537,Q9HD42 | Localization | GO Cellular component | msigdb_gocc | 132,12,150,27,28,31,157,39,40,41,43,46,50,58,67,69,73,203,213,95,218,99,238,115,260 | 1859,3072,95,157,218,2089,1291,3062,2208,2504,27,768,878,1204,69,50,2333,1773,1434,828,1482,912,1816,1634,655,2429,58,41,1156,2149,1484,46,1389,859,2254,832,954,213,1645,583,73,2466,12,43,1303,1782,2064,1876,2217,2342,2882,1123,1729,1086,2163,2475,739,115,1932,1933,2634,40,741,1401,67,2549,266,1499,3080,39,1097,557,868... | -0.23617802356071166,-2.1110040441905302,2.0329969890041335,1.5362117181364128,1.2765988138362,-0.37966711166030426,0.0916230653837448,-1.947658572174278,-0.4382834749199662,-0.6492423972397605,3.44643436310832,0.4475879086837396,0.3485751885508132,0.14413493056950505,2.3692468623114746,2.7723526302969184,-0.5275674680... | 3,120 |
Ion transmembrane transporter activity | 30 | 105 | 3.78157 | 0.000156 | P20020,O43772,Q13423,O75947,O14548,Q9Y487,P21796,P13073,P00846,Q6N075,P36542,Q8TDW0,Q9UDW1,P06576,Q9H2D1,Q14847,P30825,Q9HD20,P41440,P45880,P16615,Q9Y277,Q7KZN9,P36543,P24539,Q70HW3,Q93050,P20674,O75964,Q8N4V1 | Functions | GO Molecular function | msigdb_gomf | 377,1,133,252,388,150,160,42,52,54,305,189,56,422,61,429,63,327,73,454,452,79,335,213,94,97,99,349,114,250 | 2654,388,1149,1768,1,1066,1587,252,114,909,550,604,52,1249,910,2147,422,2703,828,1482,912,1774,2023,2383,1676,2808,2536,42,452,377,349,1389,859,160,1777,94,919,63,2513,1159,305,213,1645,73,454,2575,955,1876,2706,2397,808,2849,883,2163,2633,2108,2441,2899,1594,1219,133,1350,429,2549,1224,779,54,1308,1689,1882,1136,2552,... | -0.8057719361207141,0.8691530690352253,0.17017548246536693,-0.17996198897025922,5.144282894154371,0.22183326505174678,-0.0694704733838678,1.1517209730784248,1.818768282448762,0.32349580032456454,0.6630753264781283,0.5923317961811347,2.7276227820437797,0.11795129526109982,0.32349580032456454,-0.4088860728488319,0.824131... | 3,120 |
Lysosomal lumen | 20 | 33 | 3.762662 | 0.000168 | P54802,Q9UMR5,P04066,P16278,P06865,P38435,Q8NHP8,Q8IV08,P11117,Q13510,P50897,P10619,P17900,Q9UM22,O14773,Q14108,P38571,P06280,P15586,P08236 | Localization | GO Cellular component | msigdb_gocc | 264,549,282,283,400,537,37,39,41,44,51,58,190,65,66,67,486,232,111,247 | 534,66,1768,1773,282,232,400,829,1436,247,2429,58,41,1156,1484,111,283,190,537,486,2680,51,264,3065,44,67,39,2360,37,788,2372,65,549 | 0.6864228881683501,2.385428384194839,-0.17996198897025922,-0.17996198897025922,1.0880085580638097,1.2353427068536198,0.8466959209611702,0.39833990773856,0.011755338385683791,1.172767077784285,-0.5880217491572218,2.5128566082167416,2.903953223583945,0.17017548246536693,-0.015166862701093613,1.8370056925799199,1.08800855... | 3,120 |
Intrinsic component of mitochondrial membrane | 23 | 46 | 3.761494 | 0.000169 | Q9Y2R0,Q8NE86,P57105,Q16134,Q15388,O14925,O60830,Q9NX63,O95563,Q96NB2,Q9BPX6,Q9H9P8,Q9Y6N1,Q9Y4W6,Q13505,Q5XKP0,Q9BWH2,O95140,O75431,Q16891,Q15070,O43819,Q9GZY8 | Localization | GO Cellular component | msigdb_gocc | 2,526,405,295,294,171,176,312,550,575,595,599,204,345,76,208,216,332,464,355,104,239,510 | 171,239,176,464,1908,1629,332,550,1631,2808,1542,1081,1082,405,2441,76,104,294,295,355,586,208,1882,1745,1797,526,2232,2615,575,595,1700,2045,216,510,1702,820,599,2766,821,312,2199,1282,2,345,702,204 | 1.4775738794299105,1.2145771446757452,1.4578623634759529,0.7786741122076469,-0.2645349940023304,-0.09685523182921355,0.9579237536502591,0.6630753264781283,-0.09685523182921355,-1.000530653277979,-0.042241579625993585,0.22183326505174678,0.22183326505174678,0.8466959209611702,-0.5880217491572218,2.2376915434747073,1.927... | 3,120 |
Receptor | 14 | 38 | 3.75443 | 0.000174 | Q14108,Q99623,Q99720,Q9Y5M8,P11717,P02786,O00264,P20645,P24390,Q9Y2I1,Q8WTV0,Q9NS69,P30825,O15118 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 67,259,6,271,233,172,262,46,116,225,28,261,63,95 | 262,1334,653,95,768,172,911,1298,2703,1817,1533,1818,1072,2149,233,2096,46,116,63,567,1125,1222,67,2661,746,686,1224,2761,28,1052,259,6,261,418,225,329,271,674 | 1.1305797371850148,0.06514870608694326,0.5445741216866079,2.0329969890041335,0.4475879086837396,1.4775738794299105,0.32349580032456454,0.0916230653837448,-0.8698275055005745,-0.20798764245173287,-0.042241579625993585,-0.20798764245173287,0.22183326505174678,-0.4088860728488319,1.2353427068536198,-0.37966711166030426,2.... | 3,120 |
Protease | 23 | 107 | 3.627265 | 0.000286 | Q5BJF2,Q9H3G5,P42785,Q8TEY7,Q9NZ08,Q9HB40,Q7Z2K6,P55786,Q9UIQ6,Q96K76,Q8NHP8,P42892,Q13510,P02786,Q96E52,P22695,P10619,Q5JRX3,O14773,P61978,Q10713,Q9BYT8,O75844 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 7,10,12,142,145,24,285,29,31,297,37,43,44,172,179,303,58,307,66,322,105,245,123 | 1426,1811,1861,66,562,516,2143,1814,123,1589,2017,172,2675,2382,58,2656,2829,2431,2096,2302,1340,2253,2059,303,2306,1919,2657,2513,1302,12,43,1926,1489,2681,1822,1398,773,1165,2707,2609,2308,29,497,2754,322,1731,2610,105,1042,44,2835,2636,2404,2637,2480,1741,2267,7,307,2269,1174,3034,2789,285,2930,1506,2358,37,414,1564... | 0.011755338385683791,-0.20798764245173287,-0.23617802356071166,2.385428384194839,0.6396116988763457,0.709655477037906,-0.4088860728488319,-0.20798764245173287,1.763620063558507,-0.0694704733838678,-0.3217563066408477,1.4775738794299105,-0.8376939983695894,-0.5576999615504026,2.5128566082167416,-0.8057719361207141,-1.03... | 3,120 |
Peptidase activity | 28 | 111 | 3.535049 | 0.000408 | Q9H3G5,P42785,Q8TEY7,Q9NZ08,Q9HB40,P49721,P28074,P55786,Q7Z2K6,Q9UIQ6,Q96K76,P42892,P02786,O75976,Q96E52,P28070,P22695,P10619,Q5JRX3,O14773,Q9Y4W6,Q9UPU5,Q10713,Q9BYT8,P28072,Q9HD42,Q4J6C6,O75844 | Functions | GO Molecular function | msigdb_gomf | 10,12,142,145,24,23,151,29,285,31,297,43,172,177,179,53,303,58,307,66,345,364,105,245,117,260,120,123 | 1426,1861,66,562,1379,516,1814,123,177,1153,1589,2017,172,2675,1864,58,2829,2431,2096,2302,630,303,2975,53,117,151,1919,2657,1920,1118,1302,12,43,1926,1489,1164,23,2341,1822,1398,773,1165,2707,2308,29,835,497,3105,1348,105,2928,1735,2835,2636,1451,458,120,2267,307,2269,2611,3034,2789,285,2930,1176,1506,2041,142,359,123... | 0.011755338385683791,-0.23617802356071166,2.385428384194839,0.6396116988763457,0.038526658332115674,0.709655477037906,-0.20798764245173287,1.763620063558507,1.4578623634759529,0.17017548246536693,-0.0694704733838678,-0.3217563066408477,1.4775738794299105,-0.8376939983695894,-0.23617802356071166,2.5128566082167416,-1.03... | 3,120 |
metalloprotease | 12 | 27 | 3.515222 | 0.000439 | Q10713,P42892,P02786,Q9NZ08,Q96E52,Q9BYT8,P22695,Q7Z2K6,Q5JRX3,P55786,O75844,Q9UIQ6 | Functions | Panther Protein class | panther_protein_class | 105,43,172,145,179,245,303,285,307,29,123,31 | 516,1814,123,2017,172,2829,2096,303,1919,2513,43,773,29,105,307,285,1506,179,1754,644,1101,245,1662,1900,145,31,345 | 0.709655477037906,-0.20798764245173287,1.763620063558507,-0.3217563066408477,1.4775738794299105,-1.0337628479999912,-0.37966711166030426,1.023417311456126,-0.2645349940023304,-0.6492423972397605,2.875037373385399,0.4475879086837396,3.3430496340161606,1.9092431533941194,1.023417311456126,1.0880085580638097,-0.0151668627... | 3,120 |
Mitochondrial transmembrane transport | 21 | 49 | 3.506638 | 0.000454 | O43772,O75947,Q8NE86,P21796,Q15388,O14925,O60830,O95563,P00846,Q96NB2,P36542,P06576,Q9H2D1,Q9BPX6,Q9Y4W6,Q9BQT8,O95831,P24539,Q9UJZ1,O75964,P23786 | Processes and pathways | GO Biological process | msigdb_gobp | 1,252,526,160,294,171,176,550,52,575,305,422,61,595,345,480,86,94,512,114,379 | 171,1030,1,176,705,1814,1587,252,114,1629,909,550,86,1631,52,2147,422,1715,2808,2536,160,379,94,919,305,955,1082,2706,2849,883,2441,294,841,1882,750,526,934,1051,2615,575,595,480,61,1661,820,972,602,512,345 | 1.4775738794299105,0.24745340385816628,5.144282894154371,1.4578623634759529,0.4963293559988893,-0.20798764245173287,-0.0694704733838678,1.1517209730784248,1.818768282448762,-0.09685523182921355,0.32349580032456454,0.6630753264781283,2.119398055387944,-0.09685523182921355,2.7276227820437797,-0.4088860728488319,0.8241310... | 3,120 |
Exopeptidase activity | 10 | 32 | 3.436831 | 0.000589 | O14773,Q9H3G5,P42785,P02786,Q9NZ08,Q9HB40,P10619,P55786,O75844,Q9UIQ6 | Functions | GO Molecular function | msigdb_gomf | 66,10,12,172,145,24,58,29,123,31 | 66,123,177,172,1864,58,2829,1919,2657,1118,12,2341,2707,29,1348,2928,2835,285,2930,1506,719,477,1754,1366,10,2931,24,1662,2452,1900,145,31 | 2.385428384194839,1.763620063558507,1.4578623634759529,1.4775738794299105,-0.23617802356071166,2.5128566082167416,-1.0337628479999912,-0.2645349940023304,-0.8057719361207141,0.19607443889255075,4.218604964715891,-0.5275674680675104,-0.8698275055005745,3.3430496340161606,0.06514870608694326,-1.238060398252917,-1.0337628... | 3,120 |
Endopeptidase activity | 20 | 58 | 3.422754 | 0.00062 | Q8TEY7,Q9NZ08,P49721,P28074,Q96K76,Q96RU2,P42892,Q96E52,P28070,P22695,Q5JRX3,O14773,Q9Y4W6,Q9UPU5,Q92542,Q10713,Q9BYT8,P28072,Q4J6C6,O75844 | Functions | GO Molecular function | msigdb_gomf | 142,145,23,151,297,439,43,179,53,303,307,66,345,364,359,105,245,117,120,123 | 66,1379,516,1814,123,2675,2431,2096,2302,630,303,2975,53,117,151,2657,1920,1302,43,1926,1489,1164,23,1398,773,2707,2308,835,105,1735,2835,2636,458,120,307,2269,1176,2041,142,359,1235,1753,2555,1407,179,297,439,644,670,1101,1366,245,648,145,364,1619,2453,345 | 2.385428384194839,0.038526658332115674,0.709655477037906,-0.20798764245173287,1.763620063558507,-0.8376939983695894,-0.5880217491572218,-0.37966711166030426,-0.4976220214613302,0.5685132566383815,1.023417311456126,-1.379165978216167,2.71261432511635,1.8004585753415925,1.555594300107399,-0.8057719361207141,-0.2645349940... | 3,120 |
Alpha/Beta hydrolase fold [IPR029058] | 9 | 25 | 3.378423 | 0.000729 | Q9H3G5,P42785,Q9H6V9,P50897,Q8NCC3,Q9HB40,Q4J6C6,P07099,P10619 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 10,12,14,51,21,24,120,57,58 | 2723,2507,57,58,3064,2431,486,12,1489,2214,51,120,2930,964,2358,21,557,1801,10,14,24,167,2288,549,2499 | -0.902175152364751,-0.6492423972397605,2.5441650315108846,2.5128566082167416,-1.947658572174278,-0.5880217491572218,0.75578003326324,4.218604964715891,-0.015166862701093613,-0.4382834749199662,2.757491625277111,1.7820760211495976,-1.238060398252917,0.298283282312465,-0.5275674680675104,3.7786917531689994,0.663075326478... | 3,120 |
Metallopeptidase activity | 14 | 41 | 3.369661 | 0.000753 | Q10713,P42892,P02786,Q9NZ08,P55786,O75976,Q96E52,Q9BYT8,P22695,O75844,Q5JRX3,Q7Z2K6,Q9HD42,Q9UIQ6 | Functions | GO Molecular function | msigdb_gomf | 105,43,172,145,29,177,179,245,303,123,307,285,260,31 | 1426,1861,562,516,1814,123,177,2017,172,1864,2829,2096,303,1919,1118,43,2341,1822,773,29,105,307,2611,2789,285,1753,477,179,1754,644,1101,1366,245,2931,260,1662,2452,1900,145,31,345 | 0.011755338385683791,-0.23617802356071166,0.6396116988763457,0.709655477037906,-0.20798764245173287,1.763620063558507,1.4578623634759529,-0.3217563066408477,1.4775738794299105,-0.23617802356071166,-1.0337628479999912,-0.37966711166030426,1.023417311456126,-0.2645349940023304,0.19607443889255075,2.875037373385399,-0.527... | 3,120 |
Intrinsic component of organelle membrane | 51 | 129 | 3.359611 | 0.000781 | P20020,Q9Y2R0,Q8NE86,P57105,Q15286,Q8NC56,Q16134,Q9Y282,O43505,Q15388,P42892,O14925,O60830,O95563,Q9NX63,Q86XL3,Q96NB2,O76024,Q5BJH7,Q9NPA0,Q9NQC3,Q9BPX6,Q9H9P8,Q9Y6N1,Q13505,Q9Y4W6,O60499,Q96S52,Q96A33,Q5XKP0,Q9UH99,O95470,Q9BWH2,O95140,Q53H12,Q15006,O15118,O75431,Q16891,Q10471,Q15070,Q12981,O75298,O43819,P10321,Q1562... | Localization | GO Cellular component | msigdb_gocc | 377,2,526,405,540,287,295,33,34,294,43,171,176,550,312,434,575,565,318,462,328,595,599,204,76,345,448,341,591,208,210,449,216,332,586,472,95,464,355,351,104,611,110,239,240,383,510,506,498,250,123 | 1425,2802,3024,171,95,2862,2378,3001,34,766,1066,239,448,176,110,464,123,1908,565,1629,1294,1672,332,449,550,1631,1154,1071,240,2808,1484,377,772,1158,1974,1391,1920,1542,43,1081,1082,2064,862,2813,405,498,2633,2108,2441,351,611,76,2350,746,472,2444,104,540,294,383,295,1597,355,586,318,1455,1226,2520,208,1882,1745,3081... | 0.011755338385683791,-1.000530653277979,-1.5987473131497758,1.4775738794299105,2.0329969890041335,-1.1009154766800557,-0.5576999615504026,-1.4877287999834443,3.1697972893617217,0.4475879086837396,0.22183326505174678,1.2145771446757452,0.8014574420423553,1.4578623634759529,1.8551713497297029,0.7786741122076469,1.7636200... | 3,120 |
Impaired proprioception | 12 | 38 | 3.298753 | 0.000971 | O14773,Q8IV08,P20700,Q13217,P41440,P07196,Q9H6K4,P54802,O75298,O43819,P00846,Q9NR77 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,39,288,197,73,103,174,264,110,239,52,126 | 2291,66,2088,1199,239,110,677,332,52,1969,103,1715,1210,1917,288,2948,1487,73,1215,264,2030,2398,2758,1548,197,1000,1457,39,813,2641,1838,2794,1606,900,174,126,1667,533 | -0.4976220214613302,2.385428384194839,-0.37966711166030426,0.14413493056950505,1.2145771446757452,1.8551713497297029,0.5205132181705904,0.9579237536502591,2.7276227820437797,-0.29306044672954845,1.9271271193823978,-0.15209923198018688,0.14413493056950505,-0.2645349940023304,1.0665769311873845,-1.3081044921965708,-0.015... | 3,120 |
Mitochondrial transport | 26 | 83 | 3.242791 | 0.001184 | O43772,O75947,P55786,Q15388,O14925,O60830,Q9P0J0,P00846,P06576,P36542,Q5JRX3,Q8N4H5,P45880,Q96EK5,O14737,O95140,O95831,P24539,O75431,Q15070,Q10713,Q9UJZ1,O75964,P42765,Q9NS69,P23786 | Processes and pathways | GO Biological process | msigdb_gobp | 1,252,29,294,171,176,313,52,422,305,307,70,454,479,211,332,86,94,464,104,105,512,114,381,261,379 | 2291,2203,211,171,1379,1030,1,176,1335,464,1814,252,114,1629,332,1909,86,1631,52,2093,2147,422,1436,1913,1715,2808,2386,379,94,919,3026,2257,2628,1779,305,381,454,955,2541,1397,2576,2950,1082,862,1680,29,2849,883,1493,105,104,294,1792,841,586,307,1308,2316,1797,70,2232,1051,479,2126,1365,1101,1369,510,648,972,261,313,2... | -0.4976220214613302,-0.4382834749199662,1.297090899466863,1.4775738794299105,0.038526658332115674,0.24745340385816628,5.144282894154371,1.4578623634759529,0.06514870608694326,0.7786741122076469,-0.20798764245173287,1.1517209730784248,1.818768282448762,-0.09685523182921355,0.9579237536502591,-0.2645349940023304,2.119398... | 3,120 |
Proton transmembrane transporter activity | 14 | 35 | 3.221387 | 0.001276 | Q93050,O75947,Q13423,P20674,P13073,O14548,O75964,Q9Y487,P00846,Q7KZN9,P36542,Q9UDW1,P24539,P36543 | Functions | GO Molecular function | msigdb_gomf | 99,252,133,349,42,388,114,150,52,335,305,56,94,213 | 388,252,114,909,604,52,2147,422,1774,2383,2808,42,349,1389,859,94,919,2513,305,213,1645,2575,955,1876,2849,883,2163,2441,133,335,99,1661,56,1763,150 | 0.8691530690352253,1.1517209730784248,1.818768282448762,0.32349580032456454,0.5923317961811347,2.7276227820437797,-0.4088860728488319,0.8241310428665671,-0.17996198897025922,-0.5576999615504026,-1.000530653277979,2.875037373385399,0.9358878616746352,0.038526658332115674,0.37352278495630703,2.050407604865225,0.323495800... | 3,120 |
Vacuolar lumen | 17 | 64 | 3.214083 | 0.001309 | Q9UM22,O14773,Q14108,Q8NHP8,P10619,Q8IV08,Q13217,P11117,P54802,Q13510,P06280,P15586,P50897,P08236,P04066,P16278,P17900 | Localization | GO Cellular component | msigdb_gocc | 65,66,67,37,58,39,197,41,264,44,232,111,51,247,282,283,190 | 978,534,66,1768,2674,1386,1773,282,232,400,828,1435,829,1436,247,2429,58,41,1156,2095,1484,111,283,190,2253,2155,2256,537,486,2680,1929,51,2393,2577,2707,1166,264,2398,2473,3065,2311,2107,2033,2223,197,44,67,2548,39,2360,37,719,938,1840,576,309,788,2239,620,2414,2372,65,549,2799 | 0.2729362763877655,0.6864228881683501,2.385428384194839,-0.17996198897025922,-0.8376939983695894,0.038526658332115674,-0.17996198897025922,1.0880085580638097,1.2353427068536198,0.8466959209611702,0.39833990773856,0.011755338385683791,0.39833990773856,0.011755338385683791,1.172767077784285,-0.5880217491572218,2.51285660... | 3,120 |
Intrinsic component of mitochondrial inner membrane | 17 | 32 | 3.207986 | 0.001337 | Q16134,Q9Y2R0,O75431,Q16891,Q15070,Q8NE86,Q9H9P8,Q9Y6N1,Q9Y4W6,Q13505,O14925,O60830,Q9NX63,O95563,Q5XKP0,O43819,Q96NB2 | Localization | GO Cellular component | msigdb_gocc | 295,2,464,355,104,526,599,204,345,76,171,176,312,550,208,239,575 | 171,239,176,464,1908,550,1542,1081,2441,76,104,295,355,586,208,1882,1745,526,2615,575,2045,1702,820,599,2766,821,312,2199,2,345,702,204 | 1.4775738794299105,1.2145771446757452,1.4578623634759529,0.7786741122076469,-0.2645349940023304,0.6630753264781283,-0.042241579625993585,0.22183326505174678,-0.5880217491572218,2.2376915434747073,1.9271271193823978,1.0665769311873845,0.9358878616746352,0.616030896851247,1.3174933512024687,-0.23617802356071166,-0.152099... | 3,120 |
Protease | 21 | 80 | 3.166852 | 0.001541 | Q9H3G5,P42785,Q8TEY7,Q9NZ08,Q9HB40,P28074,Q7Z2K6,P55786,Q9UIQ6,Q96K76,P42892,O75976,Q96E52,P10619,Q5JRX3,O14773,Q9Y4W6,Q9BYT8,P28072,Q4J6C6,O75844 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 10,12,142,145,24,151,285,29,31,297,43,177,179,58,307,66,345,245,117,120,123 | 1426,1861,66,1379,516,1814,123,177,1589,2017,2675,1864,58,2829,2096,2302,117,151,1919,2657,1302,12,43,1926,1489,2341,1398,773,1165,2707,2308,29,497,3105,2835,2636,1451,458,120,307,2269,3034,285,2930,1176,2041,142,1235,1753,2555,1407,2277,179,2043,2739,297,1754,439,644,670,3051,1101,245,648,10,2931,2370,559,24,1662,2452... | 0.011755338385683791,-0.23617802356071166,2.385428384194839,0.038526658332115674,0.709655477037906,-0.20798764245173287,1.763620063558507,1.4578623634759529,-0.0694704733838678,-0.3217563066408477,-0.8376939983695894,-0.23617802356071166,2.5128566082167416,-1.0337628479999912,-0.37966711166030426,-0.4976220214613302,1.... | 3,120 |
Metalloprotease | 13 | 37 | 3.138927 | 0.001696 | Q10713,P42892,Q9Y4W6,P02786,Q9NZ08,P55786,Q96E52,Q9BYT8,P22695,Q5JRX3,Q7Z2K6,O75844,Q9UIQ6 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 105,43,345,172,145,29,179,245,303,307,285,123,31 | 1426,1861,562,516,1814,123,2017,172,2656,2829,2096,2253,303,1919,2513,43,1822,773,29,105,2480,307,2789,285,1506,414,1753,967,179,1754,644,1101,245,1900,145,31,345 | 0.011755338385683791,-0.23617802356071166,0.6396116988763457,0.709655477037906,-0.20798764245173287,1.763620063558507,-0.3217563066408477,1.4775738794299105,-0.8057719361207141,-1.0337628479999912,-0.37966711166030426,-0.46786141367036915,1.023417311456126,-0.2645349940023304,-0.6492423972397605,2.875037373385399,-0.20... | 3,120 |
Intrinsic component of plasma membrane | 15 | 78 | 3.097535 | 0.001951 | Q99805,Q9Y4G8,P41440,P11717,P20645,P02786,P10321,O15118,O60637,Q8TDW0,O43657,Q9NR28,Q8WTV0,P30825,Q9UIQ6 | Localization | GO Cellular component | msigdb_gocc | 154,168,73,233,46,172,240,95,55,189,89,251,28,63,31 | 1425,262,978,1334,653,95,802,2379,1379,89,55,2569,986,1154,172,1071,1249,910,2147,911,2703,240,1072,1676,2149,233,2808,452,1590,377,46,1777,1391,63,519,567,1159,1118,73,862,1876,2397,2161,808,2218,1125,2441,1594,1040,1043,1222,775,1045,2549,2117,686,1224,688,2358,869,1180,189,28,359,1101,154,1954,2080,2188,2919,758,251... | 0.011755338385683791,1.1305797371850148,0.2729362763877655,0.06514870608694326,0.5445741216866079,2.0329969890041335,0.42302785571210444,-0.5576999615504026,0.038526658332115674,2.102247310438612,2.575259739826172,-0.7112482098625537,0.2729362763877655,0.17017548246536693,1.4775738794299105,0.22183326505174678,0.117951... | 3,120 |
Liposaccharide metabolic process | 9 | 17 | 3.094122 | 0.001974 | P06865,Q8NBX0,P06280,Q96S52,Q99805,P04066,P16278,Q9NZD2,P17900 | Processes and pathways | GO Biological process | msigdb_gobp | 400,3,232,341,154,282,283,320,190 | 1769,1773,282,232,400,829,283,190,2223,1220,1455,3,1235,506,341,154,320 | -0.17996198897025922,-0.17996198897025922,1.0880085580638097,1.2353427068536198,0.8466959209611702,0.39833990773856,1.0880085580638097,1.4181869234230973,-0.4382834749199662,0.14413493056950505,0.011755338385683791,4.782120546298962,0.14413493056950505,0.7327741710393836,0.9579237536502591,1.555594300107399,1.001687568... | 3,120 |
Lytic vacuole organization | 7 | 24 | 3.091338 | 0.001993 | O14773,Q14108,Q9UQN3,P11117,Q9Y3E7,P50897,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 66,67,132,41,203,51,27 | 1859,66,27,768,730,1773,829,2429,41,2466,51,2064,264,1086,67,1499,2318,693,2126,1368,1024,2415,132,203 | -0.23617802356071166,2.385428384194839,3.44643436310832,0.4475879086837396,0.47202132781882844,-0.17996198897025922,0.39833990773856,-0.5880217491572218,2.903953223583945,-0.6185351182463072,2.757491625277111,-0.35062453129738713,1.1305797371850148,0.22183326505174678,2.385428384194839,-0.015166862701093613,-0.49762202... | 3,120 |
Cation transmembrane transporter activity | 21 | 75 | 3.079818 | 0.002071 | P20020,O43772,O75947,Q13423,O14548,Q9Y487,P13073,P00846,P06576,P36542,Q9UDW1,P30825,Q9HD20,Q7KZN9,P36543,P24539,Q70HW3,Q93050,P20674,O75964,Q8N4V1 | Functions | GO Molecular function | msigdb_gomf | 377,1,252,133,388,150,42,52,422,305,56,63,327,335,213,94,97,99,349,114,250 | 388,1,1066,252,114,909,604,52,1249,910,2147,422,2703,828,1482,912,1774,2383,2808,42,452,377,349,1389,859,1777,94,919,63,2513,1159,305,213,1645,2575,955,1876,808,2849,883,2163,2633,2108,2441,2899,1219,133,2549,1224,779,1136,2552,97,335,250,526,1180,1183,1052,99,575,1954,1102,2919,758,1661,820,2766,327,852,56,1763,1194,1... | 0.8691530690352253,5.144282894154371,0.22183326505174678,1.1517209730784248,1.818768282448762,0.32349580032456454,0.5923317961811347,2.7276227820437797,0.11795129526109982,0.32349580032456454,-0.4088860728488319,0.8241310428665671,-0.8698275055005745,0.39833990773856,-0.015166862701093613,0.32349580032456454,-0.1799619... | 3,120 |
Glycerolipid biosynthetic process | 7 | 42 | 3.05639 | 0.00224 | P35790,Q9NPH0,Q9NX62,Q10713,Q8NCC3,Q9BVG9,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 0,5,137,105,21,85,28 | 2501,156,2924,1377,1769,1481,2297,2623,2018,2302,1254,0,2847,3059,1786,105,1945,1455,1688,2178,1883,1796,21,868,894,28,1838,1183,1235,506,668,669,341,2819,2188,85,1804,5,2132,3000,137,2199 | -0.6492423972397605,1.5362117181364128,-1.238060398252917,0.038526658332115674,-0.17996198897025922,-0.015166862701093613,-0.4976220214613302,-0.7740586736982547,-0.3217563066408477,-0.4976220214613302,0.11795129526109982,5.899253810656477,-1.0672234487170145,-1.9076504275094626,-0.17996198897025922,1.9092431533941194,... | 3,120 |
Metalloprotease | 10 | 27 | 3.053058 | 0.002265 | P42892,Q9NZ08,O75976,Q96E52,Q9BYT8,Q7Z2K6,Q5JRX3,P55786,O75844,Q9UIQ6 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 43,145,177,179,245,285,307,29,123,31 | 1861,516,1814,123,177,2017,1864,2829,2096,43,773,29,307,285,1753,179,1754,644,1101,245,2931,1662,2452,1900,145,31,345 | -0.23617802356071166,0.709655477037906,-0.20798764245173287,1.763620063558507,1.4578623634759529,-0.3217563066408477,-0.23617802356071166,-1.0337628479999912,-0.37966711166030426,2.875037373385399,0.4475879086837396,3.3430496340161606,1.023417311456126,1.0880085580638097,-0.15209923198018688,1.4578623634759529,-0.15209... | 3,120 |
Inorganic molecular entity transmembrane transporter activity | 23 | 76 | 3.031536 | 0.002433 | P20020,O75947,Q13423,O14548,Q9Y487,P21796,P13073,P00846,P06576,P36542,Q6N075,Q9UDW1,Q8TDW0,Q9HD20,P45880,Q9Y277,Q7KZN9,P36543,P24539,Q93050,P20674,O75964,Q8N4V1 | Functions | GO Molecular function | msigdb_gomf | 377,252,133,388,150,160,42,52,422,305,54,56,189,327,454,79,335,213,94,99,349,114,250 | 2654,388,1768,252,114,909,604,52,1249,910,2147,422,2703,828,1482,912,1774,2023,2383,2808,42,452,377,349,1389,859,160,1777,94,919,2513,1159,305,213,1645,454,2575,955,1876,808,2849,883,2163,2633,2108,2441,2899,1594,1219,133,2549,779,54,1136,335,250,526,1180,189,1052,99,1101,1102,2919,758,1661,327,852,797,56,1763,1194,79,... | -0.8057719361207141,0.8691530690352253,-0.17996198897025922,1.1517209730784248,1.818768282448762,0.32349580032456454,0.5923317961811347,2.7276227820437797,0.11795129526109982,0.32349580032456454,-0.4088860728488319,0.8241310428665671,-0.8698275055005745,0.39833990773856,-0.015166862701093613,0.32349580032456454,-0.1799... | 3,120 |
Negative regulation of mrna metabolic process | 25 | 45 | 3.010849 | 0.002605 | P38159,O60506,Q6PJT7,Q92804,Q08170,Q07021,O00422,P67809,P98175,O00267,Q13247,Q9Y2W1,P61978,P22626,P07910,Q99729,Q14011,Q16629,Q5VTR2,Q14103,Q13151,Q13242,O75150,P26368,P35637 | Processes and pathways | GO Biological process | msigdb_gobp | 140,517,664,153,774,408,652,291,426,800,570,329,322,321,205,342,81,227,617,615,612,234,484,737,248 | 1709,800,652,517,484,803,1433,205,1819,2912,2459,321,737,1033,248,140,1083,322,291,426,2660,408,774,1936,885,1221,612,234,570,81,615,1452,962,2870,227,617,1948,664,1560,1752,153,342,1274,1806,329 | -0.15209923198018688,0.42302785571210444,0.5445741216866079,0.709655477037906,0.75578003326324,0.42302785571210444,0.011755338385683791,1.3174933512024687,-0.20798764245173287,-1.2034112370325538,-0.6185351182463072,0.979856683830239,0.47202132781882844,0.24745340385816628,1.172767077784285,1.6323249879473072,0.2218332... | 3,120 |
Endocytic vesicle membrane | 8 | 42 | 2.992382 | 0.002768 | Q93050,Q14108,P11717,P20645,P02786,Q15907,Q9Y487,Q8WTV0 | Localization | GO Cellular component | msigdb_gocc | 99,67,233,46,172,49,150,28 | 1857,704,1380,1204,2333,1154,172,1071,240,2149,233,2384,1484,1158,46,1974,1724,2064,2217,2342,1984,1823,2163,2475,1933,1786,1219,1169,2477,2584,67,540,2117,49,2761,28,99,2713,1368,1059,1371,150 | -0.23617802356071166,0.4963293559988893,0.038526658332115674,0.14413493056950505,-0.5275674680675104,0.17017548246536693,1.4775738794299105,0.22183326505174678,1.2145771446757452,-0.4088860728488319,1.2353427068536198,-0.5576999615504026,-0.015166862701093613,0.17017548246536693,2.831314292458711,-0.29306044672954845,-... | 3,120 |
Proton transporting two sector atpase complex | 9 | 21 | 2.987412 | 0.002813 | Q93050,O75947,Q96IX5,O75964,Q9Y487,P00846,P36543,Q15904,P24539 | Localization | GO Cellular component | msigdb_gocc | 99,252,230,114,150,52,213,186,94 | 768,252,114,52,422,1389,859,94,919,305,213,1645,955,2849,883,2163,186,99,230,1763,150 | 0.4475879086837396,1.1517209730784248,1.818768282448762,2.7276227820437797,0.8241310428665671,0.038526658332115674,0.37352278495630703,2.050407604865225,0.32349580032456454,1.023417311456126,1.297090899466863,-0.09685523182921355,0.298283282312465,-1.0672234487170145,0.3485751885508132,-0.4088860728488319,1.43806694005... | 3,120 |
Cytochrome complex | 8 | 18 | 2.986819 | 0.002819 | P14406,P20674,P13073,Q7KZN9,Q9UDW1,P22695,O14949,P14927 | Localization | GO Cellular component | msigdb_gocc | 72,349,42,335,56,303,26,93 | 1522,388,26,604,1774,913,2383,42,72,93,1388,349,303,2513,2575,335,56,1476 | -0.042241579625993585,0.8691530690352253,3.459191262825689,0.5923317961811347,-0.17996198897025922,0.32349580032456454,-0.5576999615504026,2.875037373385399,2.336710950263473,2.050407604865225,0.038526658332115674,0.9358878616746352,1.023417311456126,-0.6492423972397605,-0.7112482098625537,0.9579237536502591,2.57525973... | 3,120 |
Ion transport | 17 | 55 | 2.986407 | 0.002823 | P20020,Q93050,O75947,P45880,Q9Y277,O75964,Q9Y487,P00846,P06576,P36542,Q6N075,P24539,Q15904,P36543,P21796,Q8TDW0,Q14847 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 377,99,252,454,79,114,150,52,422,305,54,94,186,213,160,189,429 | 2654,252,114,909,1631,52,1249,910,422,2023,452,377,1389,859,160,1777,94,919,1159,305,213,1645,454,955,1876,2161,808,2849,883,2163,2108,1219,429,2549,186,779,54,1136,2552,1007,526,1180,189,99,2615,595,901,757,758,1763,1194,79,150,3014,1196 | -0.8057719361207141,1.1517209730784248,1.818768282448762,0.32349580032456454,-0.09685523182921355,2.7276227820437797,0.11795129526109982,0.32349580032456454,0.8241310428665671,-0.3217563066408477,0.8014574420423553,0.8915034664671595,0.038526658332115674,0.37352278495630703,1.5362117181364128,-0.17996198897025922,2.050... | 3,120 |
Aminoglycan metabolic process | 9 | 16 | 2.983745 | 0.002847 | O43505,Q96L58,Q9NX62,P54802,P15586,Q7LGA3,P08236,P04066,Q8NCH0 | Processes and pathways | GO Biological process | msigdb_gobp | 34,166,137,264,111,19,247,282,161 | 34,3015,2333,282,400,829,247,111,283,264,1933,1220,19,161,166,137 | 3.1697972893617217,-1.561461734297637,-0.5275674680675104,1.0880085580638097,0.8466959209611702,0.39833990773856,1.172767077784285,1.8370056925799199,1.0880085580638097,1.1305797371850148,-0.2645349940023304,0.14413493056950505,3.9302356800799503,1.5362117181364128,1.516747891198495,1.651310887354022 | 3,120 |
SLC superfamily of solute carriers | 6 | 44 | 2.966339 | 0.003014 | O43772,P41440,Q6N075,Q8IXU6,Q9H2D1,P30825 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 1,73,54,22,61,63 | 1,1066,1587,909,550,2147,912,1676,2808,2536,63,73,2706,2397,808,2441,1594,2549,1224,54,1308,1689,2552,97,22,1180,2075,1183,575,1954,480,1102,2919,61,758,1661,820,2766,1059,2372,797,602,2500,1196 | 5.144282894154371,0.22183326505174678,-0.0694704733838678,0.32349580032456454,0.6630753264781283,-0.4088860728488319,0.32349580032456454,-0.12439757025387724,-1.000530653277979,-0.6801459566044995,2.449587253406975,2.3039419144770994,-0.8698275055005745,-0.5576999615504026,0.42302785571210444,-0.5880217491572218,-0.069... | 3,120 |
Lower limb amyotrophy | 11 | 18 | 2.939091 | 0.003292 | P04792,P02545,Q9Y6X9,P07196,P06753,O75298,O14908,O95140,Q8TD16,Q9NR77,Q92734 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 128,376,533,103,450,110,579,332,188,126,386 | 579,110,332,376,128,450,103,1917,1733,634,1992,1000,1556,188,386,126,1107,533 | 0.616030896851247,1.8551713497297029,0.9579237536502591,0.8915034664671595,1.7264856813353782,0.8014574420423553,1.9271271193823978,-0.2645349940023304,-0.15209923198018688,0.5685132566383815,-0.29306044672954845,0.2729362763877655,-0.042241579625993585,1.4380669400587471,0.8915034664671595,1.763620063558507,0.22183326... | 3,120 |
Glycosaminoglycan metabolism | 8 | 15 | 2.929547 | 0.003395 | O43505,Q96L58,P54802,P15586,Q7LGA3,P08236,P16278,Q8NCH0 | Processes and pathways | Reactome Pathways | msigdb_reactome | 34,166,264,111,19,247,283,161 | 1247,34,400,829,247,111,283,264,1220,19,161,2075,166,558,2562 | 0.11795129526109982,3.1697972893617217,0.8466959209611702,0.39833990773856,1.172767077784285,1.8370056925799199,1.0880085580638097,1.1305797371850148,0.14413493056950505,3.9302356800799503,1.5362117181364128,-0.35062453129738713,1.516747891198495,0.6630753264781283,-0.6801459566044995 | 3,120 |
Serine hydrolase activity | 6 | 18 | 2.929093 | 0.0034 | O14773,Q9H3G5,P42785,Q9HB40,Q4J6C6,P10619 | Functions | GO Molecular function | msigdb_gomf | 66,10,12,24,120,58 | 66,1379,177,58,2431,2657,1302,12,1489,1165,2707,458,120,307,2930,648,10,24 | 2.385428384194839,0.038526658332115674,1.4578623634759529,2.5128566082167416,-0.5880217491572218,-0.8057719361207141,0.0916230653837448,4.218604964715891,-0.015166862701093613,0.17017548246536693,-0.8698275055005745,0.8014574420423553,1.7820760211495976,1.023417311456126,-1.238060398252917,0.5685132566383815,4.35601793... | 3,120 |
Organic acid transmembrane transport | 11 | 30 | 2.927587 | 0.003416 | P08183,O43772,P23786,P41440,O95563,Q9BQT8,Q96NB2,Q8TDW0,Q9H2D1,P31751,P30825 | Processes and pathways | GO Biological process | msigdb_gobp | 64,1,379,73,550,480,575,189,61,183,63 | 1,1967,1587,1628,550,911,64,912,1676,379,2212,63,183,1254,73,1082,2706,2397,1594,2444,1224,189,575,480,61,758,1661,820,797,602 | 5.144282894154371,-0.29306044672954845,-0.0694704733838678,-0.09685523182921355,0.6630753264781283,0.32349580032456454,2.401552801979837,0.32349580032456454,-0.12439757025387724,0.8915034664671595,-0.4382834749199662,2.449587253406975,1.4380669400587471,0.11795129526109982,2.3039419144770994,0.22183326505174678,-0.8698... | 3,120 |
Signaling by insulin receptor | 6 | 15 | 2.919879 | 0.003502 | O00459,Q93050,Q9Y487,P62993,Q15904,P31751 | Processes and pathways | Reactome Pathways | msigdb_reactome | 156,99,150,148,186,183 | 156,1389,859,831,2155,183,213,1645,2163,148,2583,186,99,1763,150 | 1.5362117181364128,0.038526658332115674,0.37352278495630703,0.39833990773856,-0.4088860728488319,1.4380669400587471,1.297090899466863,-0.09685523182921355,-0.4088860728488319,1.5748962832288216,-0.7112482098625537,1.4380669400587471,1.9979768307458792,-0.15209923198018688,1.5748962832288216 | 3,120 |
Proximal muscle weakness | 24 | 63 | 2.911935 | 0.003592 | P02545,Q9Y6X9,Q99720,P51114,O60313,Q13126,Q8NI60,Q8WXH0,P50402,Q13510,P00846,Q8TD16,Q9BPX6,P06753,P22626,Q9BQT8,Q86U42,O14908,O95140,P07196,Q92734,P35637,Q13501,P21912 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 376,533,6,391,389,20,413,543,289,44,52,188,595,450,321,480,337,579,332,103,386,248,382,378 | 579,389,856,332,1295,52,376,2146,450,103,2428,1339,2429,1437,2808,1484,1916,1917,378,2254,321,2387,248,1159,1118,1081,289,1724,391,608,2706,1215,2398,2758,2610,20,1221,382,44,2785,2661,2548,1992,1001,2227,1094,337,2641,2273,413,2232,188,543,386,1606,6,595,480,1054,1755,671,2134,533 | 0.616030896851247,0.8691530690352253,0.37352278495630703,0.9579237536502591,0.0916230653837448,2.7276227820437797,0.8915034664671595,-0.4088860728488319,0.8014574420423553,1.9271271193823978,-0.5880217491572218,0.06514870608694326,-0.5880217491572218,0.011755338385683791,-1.000530653277979,-0.015166862701093613,-0.2645... | 3,120 |
Hydrogen ion transport | 9 | 19 | 2.900343 | 0.003728 | Q93050,O75947,O75964,Q9Y487,P00846,P36542,P36543,Q15904,P24539 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 99,252,114,150,52,305,213,186,94 | 252,114,52,422,1389,859,94,919,305,213,1645,955,2849,883,2163,186,99,1763,150 | 1.1517209730784248,1.818768282448762,2.7276227820437797,0.8241310428665671,0.038526658332115674,0.37352278495630703,2.050407604865225,0.32349580032456454,1.023417311456126,1.297090899466863,-0.09685523182921355,0.298283282312465,-1.0672234487170145,0.3485751885508132,-0.4088860728488319,1.4380669400587471,1.99797683074... | 3,120 |
Motor neuron atrophy | 8 | 24 | 2.896839 | 0.003769 | P35637,Q9UQN3,Q99720,P22626,Q13510,Q15165,Q92734,Q92804 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 248,132,6,321,44,112,386,153 | 1295,3002,1339,2254,321,1871,248,861,1442,2398,1221,382,44,714,112,2227,386,153,900,6,1660,1899,1327,132 | 0.0916230653837448,-1.4877287999834443,0.06514870608694326,-0.46786141367036915,0.979856683830239,-0.23617802356071166,1.172767077784285,0.37352278495630703,0.011755338385683791,-0.5576999615504026,0.14413493056950505,0.8915034664671595,2.860509873296997,0.4963293559988893,1.8370056925799199,-0.4382834749199662,0.89150... | 3,120 |
Distal lower limb amyotrophy | 10 | 14 | 2.890507 | 0.003846 | P04792,P02545,Q9Y6X9,P07196,P06753,O14908,O95140,Q8TD16,Q9NR77,Q92734 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 128,376,533,103,450,579,332,188,126,386 | 579,332,376,128,450,103,634,1992,1000,1556,188,386,126,533 | 0.616030896851247,0.9579237536502591,0.8915034664671595,1.7264856813353782,0.8014574420423553,1.9271271193823978,0.5685132566383815,-0.29306044672954845,0.2729362763877655,-0.042241579625993585,1.4380669400587471,0.8915034664671595,1.763620063558507,0.709655477037906 | 3,120 |
ATP synthase | 9 | 20 | 2.889957 | 0.003853 | Q93050,O75947,Q96IX5,O75964,Q9Y487,P00846,P36542,Q15904,P24539 | Functions | Panther Protein class | panther_protein_class | 99,252,230,114,150,52,305,186,94 | 252,114,52,422,1389,859,94,919,305,1645,955,2849,883,2163,186,1947,99,230,1763,150 | 1.1517209730784248,1.818768282448762,2.7276227820437797,0.8241310428665671,0.038526658332115674,0.37352278495630703,2.050407604865225,0.32349580032456454,1.023417311456126,-0.09685523182921355,0.298283282312465,-1.0672234487170145,0.3485751885508132,-0.4088860728488319,1.4380669400587471,-0.2645349940023304,1.997976830... | 3,120 |
Calcium-binding protein | 6 | 20 | 2.884045 | 0.003926 | O43852,P80303,P43307,Q99584,Q14257,Q02818 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 134,15,17,244,87,30 | 134,1974,1922,1119,17,2783,3032,15,30,87,249,1690,812,750,1358,1186,244,595,1272,1373 | 1.6702193073777245,-0.29306044672954845,-0.2645349940023304,0.19607443889255075,3.953097547841211,-0.9675239012000673,-1.6363177401147757,4.05454044544889,3.3299572675677735,2.119398055387944,1.172767077784285,-0.12439757025387724,0.42302785571210444,0.47202132781882844,0.06514870608694326,0.17017548246536693,1.1937188... | 3,120 |
Mitochondrial calcium ion transport | 12 | 17 | 2.864235 | 0.00418 | Q9BPX6,Q8NE86,Q10713,Q9Y4W6,P45880,Q9Y277,Q9UJZ1,P35232,Q96TA2,Q9H300,P21796,Q99623 | Processes and pathways | Reactome Pathways | msigdb_reactome | 595,526,105,345,454,79,512,519,644,648,160,259 | 1814,909,160,519,454,105,750,526,1051,1406,644,259,595,648,512,79,345 | -0.20798764245173287,0.32349580032456454,1.5362117181364128,0.709655477037906,0.8014574420423553,1.9092431533941194,0.47202132781882844,0.709655477037906,0.24745340385816628,0.038526658332115674,0.5685132566383815,1.1517209730784248,0.616030896851247,0.5685132566383815,0.7327741710393836,2.2209781437623697,0.9579237536... | 3,120 |
Cardiac muscle contraction | 10 | 22 | 2.856328 | 0.004286 | P67936,P14406,P06753,P13073,O14548,P20674,Q9UDW1,P22695,O14949,P14927 | Processes and pathways | KEGG Pathways | msigdb_kegg | 457,72,450,42,388,349,56,303,26,93 | 388,26,604,1249,910,450,1774,629,913,2383,42,72,93,1388,452,349,303,2513,2575,2161,457,56 | 0.8691530690352253,3.459191262825689,0.5923317961811347,0.11795129526109982,0.32349580032456454,0.8014574420423553,-0.17996198897025922,0.5685132566383815,0.32349580032456454,-0.5576999615504026,2.875037373385399,2.336710950263473,2.050407604865225,0.038526658332115674,0.8014574420423553,0.9358878616746352,1.0234173114... | 3,120 |
SH3 domain [IPR001452] | 17 | 40 | 2.83496 | 0.004583 | O00459,Q13813,Q9NZQ3,Q9UQB8,Q9UPN3,Q9H6R6,Q14168,Q9NZW5,P62993,Q12959,O75962,Q5JRA6,Q15642,P46108,Q96PC5,Q14847,Q03001 | Sequence | InterPro Domain | interpro_domain | 156,394,202,13,373,143,571,578,148,502,273,384,473,125,223,429,500 | 156,2531,273,1031,605,1776,1256,125,2753,148,922,500,836,502,394,1046,571,744,961,429,1001,473,384,1008,223,1364,1607,143,2979,202,578,947,1579,1147,1283,373,13,1027,854,2600 | 1.5362117181364128,-0.6801459566044995,1.1093425443192109,0.24745340385816628,0.5923317961811347,-0.17996198897025922,0.11795129526109982,1.763620063558507,-0.9347396848564197,1.5748962832288216,0.32349580032456454,0.7327741710393836,0.39833990773856,0.7327741710393836,0.8691530690352253,0.24745340385816628,0.639611698... | 3,120 |
Rnd2 gtpase cycle | 6 | 18 | 2.824428 | 0.004737 | O00459,Q8TAA9,Q07065,P38159,P02786,P51648 | Processes and pathways | Reactome Pathways | msigdb_reactome | 156,131,40,140,172,91 | 156,1584,172,140,91,500,40,1126,1449,1652,688,131,1364,441,2371,799,225,763 | 1.5362117181364128,-0.0694704733838678,1.4775738794299105,1.6323249879473072,2.0677525498216016,0.7327741710393836,3.031833480450284,0.19607443889255075,0.011755338385683791,-0.09685523182921355,0.5205132181705904,1.7078061122023387,0.06514870608694326,0.8241310428665671,-0.5275674680675104,0.4475879086837396,1.2765988... | 3,120 |
Vacuole | 45 | 210 | 2.820453 | 0.004796 | Q9UQN3,Q5BJF2,Q9UHG3,Q9NRR5,Q16625,P42785,P54802,Q9Y487,Q8NCC3,P04066,O75503,Q8WTV0,P19474,Q9UIQ6,O15260,Q8NHP8,Q8IV08,Q07065,P11117,P42892,Q13510,P20645,O95772,P50897,P10619,P17900,Q9UM22,O14773,Q14108,O95721,Q13217,P41440,Q9Y3E7,P36543,O15118,O15400,Q93050,Q9Y6I9,Q969Q5,P06280,Q15165,P15586,P78537,P08236,Q9HD42 | Localization | GO Cellular component | msigdb_gocc | 132,7,8,269,266,12,264,150,21,282,27,28,159,31,157,37,39,40,41,43,44,46,50,51,58,190,65,66,67,69,197,73,203,213,95,218,99,238,108,232,112,111,115,247,260 | 1857,1859,978,534,3072,66,1376,95,157,218,765,1768,2089,1291,420,3062,2208,2504,1381,27,768,878,1204,69,50,2333,2508,2674,1070,1386,1773,282,1434,232,400,828,2675,1435,829,1436,1482,912,247,1816,1634,655,1387,2429,58,41,1156,2095,2149,1484,111,283,2302,190,159,46,2253,1389,859,2254,3041,1974,2155,2256,2024,832,954,213,... | -0.23617802356071166,-0.23617802356071166,0.2729362763877655,0.6864228881683501,-2.1110040441905302,2.385428384194839,0.038526658332115674,2.0329969890041335,1.5362117181364128,1.2765988138362,0.4475879086837396,-0.17996198897025922,-0.37966711166030426,0.0916230653837448,0.8241310428665671,-1.947658572174278,-0.438283... | 3,120 |
Somatic sensory dysfunction | 21 | 98 | 2.81465 | 0.004883 | P04792,P54802,Q9NZ08,Q8NCH0,Q8IV08,P20700,Q9H6K4,P00846,O14773,Q13217,P61978,P41440,Q9NSE4,O95831,O95140,P07196,O75298,P06280,O43819,Q92734,Q9NR77 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 128,264,145,161,39,288,174,52,66,197,322,73,344,86,332,103,110,232,239,386,126 | 2291,2203,66,2088,1199,979,2804,2878,239,110,677,332,2621,1910,86,52,1154,376,2093,128,2863,232,1969,103,2675,829,2428,1715,1676,1536,1210,1917,288,1776,1974,1392,2387,2948,1487,73,861,1036,2630,2214,1781,1081,1724,2064,1121,2469,1215,2609,264,2030,2398,1785,2471,2542,322,2758,1548,1219,1733,522,197,2548,1450,2587,1000... | -0.4976220214613302,-0.4382834749199662,2.385428384194839,-0.37966711166030426,0.14413493056950505,0.2729362763877655,-1.000530653277979,-1.1348420125464262,1.2145771446757452,1.8551713497297029,0.5205132181705904,0.9579237536502591,-0.7740586736982547,-0.2645349940023304,2.119398055387944,2.7276227820437797,0.17017548... | 3,120 |
Intermediate filament | 11 | 20 | 2.803872 | 0.005049 | P02545,Q03252,P07196,P20700,P08670,Q16352,Q9NZQ3,Q9UPN3,O75298,P07197,Q03001 | Localization | GO Cellular component | msigdb_gocc | 376,255,103,288,139,556,202,373,110,423,500 | 1334,110,376,103,423,139,1820,1031,288,660,1928,2031,1727,500,255,1001,556,1057,202,373 | 0.06514870608694326,1.8551713497297029,0.8915034664671595,1.9271271193823978,0.8241310428665671,1.6323249879473072,-0.20798764245173287,0.24745340385816628,1.0665769311873845,0.5445741216866079,-0.2645349940023304,-0.3217563066408477,-0.15209923198018688,0.7327741710393836,1.1517209730784248,0.2729362763877655,0.663075... | 3,120 |
Insulin resistance | 10 | 18 | 2.792554 | 0.005229 | P02545,O75431,Q03252,O00330,P17096,O95140,Q96MF7,P31751,O75844,Q8NC56 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 376,464,255,483,206,332,162,183,123,287 | 2530,483,464,123,565,332,376,206,1250,1538,183,2101,1162,255,287,162,1512,826 | -0.6801459566044995,0.75578003326324,0.7786741122076469,1.763620063558507,0.6396116988763457,0.9579237536502591,0.8915034664671595,1.3174933512024687,0.11795129526109982,-0.042241579625993585,1.4380669400587471,-0.37966711166030426,0.17017548246536693,1.1517209730784248,1.0880085580638097,1.5362117181364128,-0.01516686... | 3,120 |
Abnormal neuron morphology | 8 | 29 | 2.790042 | 0.00527 | P35637,Q9UQN3,Q99720,P22626,Q13510,Q15165,Q92734,Q92804 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 248,132,6,321,44,112,386,153 | 2088,677,1295,3002,1339,1211,2254,321,1871,248,861,1442,2030,2398,1221,382,44,714,112,2227,1050,386,153,900,6,1660,1899,1327,132 | -0.37966711166030426,0.5205132181705904,0.0916230653837448,-1.4877287999834443,0.06514870608694326,0.14413493056950505,-0.46786141367036915,0.979856683830239,-0.23617802356071166,1.172767077784285,0.37352278495630703,0.011755338385683791,-0.3217563066408477,-0.5576999615504026,0.14413493056950505,0.8915034664671595,2.8... | 3,120 |
Disproportionate short stature | 8 | 24 | 2.780829 | 0.005422 | Q7RTS9,Q6DKJ4,Q15392,Q32P28,O75718,Q7LGA3,P16278,Q96MF7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,220,130,74,346,19,283,162 | 950,1377,2014,346,807,283,1638,2466,1304,1684,746,1738,130,74,220,19,32,2073,528,162,2888,1322,2597,397 | 0.298283282312465,0.038526658332115674,-0.3217563066408477,0.9358878616746352,0.42302785571210444,1.0880085580638097,-0.09685523182921355,-0.6185351182463072,0.0916230653837448,-0.12439757025387724,0.47202132781882844,-0.15209923198018688,1.7078061122023387,2.3039419144770994,1.2765988138362,3.9302356800799503,3.210375... | 3,120 |
Metalloendopeptidase activity | 7 | 15 | 2.780196 | 0.005433 | Q10713,P42892,Q96E52,Q9BYT8,P22695,Q5JRX3,O75844 | Functions | GO Molecular function | msigdb_gomf | 105,43,179,245,303,307,123 | 516,1814,123,2096,303,43,773,105,307,1753,179,644,1101,245,345 | 0.709655477037906,-0.20798764245173287,1.763620063558507,-0.37966711166030426,1.023417311456126,2.875037373385399,0.4475879086837396,1.9092431533941194,1.023417311456126,-0.15209923198018688,1.4578623634759529,0.5685132566383815,0.22183326505174678,1.193718866633161,0.9579237536502591 | 3,120 |
Outer mitochondrial membrane protein complex | 7 | 15 | 2.779744 | 0.00544 | Q15388,Q16891,Q8N4H5,Q13505,Q5XKP0,Q9NX63,Q9NS69 | Localization | GO Cellular component | msigdb_gocc | 294,355,70,76,208,312,261 | 464,1629,1631,1542,76,294,355,208,1745,70,2045,261,821,312,702 | 0.7786741122076469,-0.09685523182921355,-0.09685523182921355,-0.042241579625993585,2.2376915434747073,1.0665769311873845,0.9358878616746352,1.3174933512024687,-0.15209923198018688,2.3692468623114746,-0.3217563066408477,1.1517209730784248,0.42302785571210444,1.023417311456126,0.5205132181705904 | 3,120 |
Positive regulation of mrna splicing via spliceosome | 7 | 16 | 2.776547 | 0.005494 | Q9Y2W1,P38159,P62995,P98179,Q13595,Q14011,P19338 | Processes and pathways | GO Biological process | msigdb_gobp | 329,140,265,48,242,81,241 | 1338,1156,241,2256,140,1165,265,48,2068,613,242,81,490,1566,1666,329 | 0.06514870608694326,0.17017548246536693,1.2145771446757452,-0.46786141367036915,1.6323249879473072,0.17017548246536693,1.1305797371850148,2.801929332566857,-0.35062453129738713,0.5923317961811347,1.2145771446757452,2.2042035774756688,0.75578003326324,-0.042241579625993585,-0.09685523182921355,0.979856683830239 | 3,120 |
Molecular transducer activity | 9 | 32 | 2.771065 | 0.005587 | Q14108,Q99720,Q9Y6I9,P11717,P20645,Q9UBG0,Q15629,Q8WTV0,O15118 | Functions | GO Molecular function | msigdb_gomf | 67,6,238,233,46,418,383,28,95 | 1334,653,95,768,911,2703,1072,233,46,2628,2101,1591,2214,740,1040,1222,67,686,383,1224,638,2761,28,1052,1570,6,2492,443,1415,418,875,238 | 0.06514870608694326,0.5445741216866079,2.0329969890041335,0.4475879086837396,0.32349580032456454,-0.8698275055005745,0.22183326505174678,1.2353427068536198,2.831314292458711,-0.7740586736982547,-0.37966711166030426,-0.0694704733838678,-0.4382834749199662,0.47202132781882844,0.24745340385816628,0.14413493056950505,2.385... | 3,120 |
Cristae formation | 10 | 20 | 2.770991 | 0.005589 | Q16891,O75947,Q13505,Q5XKP0,Q9NX63,O75964,P00846,P06576,P36542,P24539 | Processes and pathways | Reactome Pathways | msigdb_reactome | 355,252,76,208,312,114,52,422,305,94 | 464,252,114,52,422,94,919,305,1542,955,2849,883,76,355,208,1745,2045,821,312,702 | 0.7786741122076469,1.1517209730784248,1.818768282448762,2.7276227820437797,0.8241310428665671,2.050407604865225,0.32349580032456454,1.023417311456126,-0.042241579625993585,0.298283282312465,-1.0672234487170145,0.3485751885508132,2.2376915434747073,0.9358878616746352,1.3174933512024687,-0.15209923198018688,-0.3217563066... | 3,120 |
Mental deterioration | 27 | 102 | 2.746568 | 0.006022 | Q9UQN3,P54802,O60313,Q9Y487,P16278,O75503,P06865,P20700,Q13510,P50897,P00846,Q9NQZ5,P17900,Q9NPL8,Q14108,Q96F07,P22626,O95470,Q5XKP0,O95140,P36543,O15118,Q10713,O43819,P35637,Q13501,P21912 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 132,264,389,150,283,27,400,288,44,51,52,181,190,463,67,325,321,449,208,332,213,95,105,239,248,382,378 | 1197,95,1379,1768,239,389,1151,2504,2294,27,565,332,1711,1480,449,1631,604,52,1386,3087,1773,2937,2092,400,829,2428,1534,1339,1914,807,283,1536,190,288,378,466,321,2305,2626,2387,1871,248,1159,213,1645,1161,2339,861,1781,51,2468,1121,1215,264,2030,2398,3065,569,1933,1261,2634,105,999,1221,382,44,67,714,2587,2852,208,28... | 0.14413493056950505,2.0329969890041335,0.038526658332115674,-0.17996198897025922,1.2145771446757452,0.8691530690352253,0.17017548246536693,-0.6492423972397605,-0.4976220214613302,3.44643436310832,0.6396116988763457,0.9579237536502591,-0.15209923198018688,-0.015166862701093613,0.8014574420423553,-0.09685523182921355,0.5... | 3,120 |
Abnormal vertebral morphology | 34 | 111 | 2.739399 | 0.006155 | Q8TAA9,Q9UHX1,Q96HY6,P57740,P54802,P04066,P16278,Q8NCH0,Q7RTS9,Q96AY3,Q96L58,P48735,P39019,P10619,Q02127,Q14999,Q9Y2W2,Q14108,Q15056,Q32P28,P61978,Q9NSE4,O95831,O60826,P82650,Q6DKJ4,Q15427,Q9H0W5,Q10713,O96028,O75718,P15586,P08236,Q5JRA6 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 131,397,528,393,264,282,283,161,32,436,166,306,425,58,427,430,330,67,323,74,322,344,86,331,469,220,490,492,105,347,346,111,247,384 | 2203,2204,2088,1377,2331,2423,2503,2142,627,331,2014,346,1588,1202,2806,909,86,347,1070,1773,282,1632,247,58,807,2893,111,283,1209,1635,1389,2573,2938,1638,708,2433,2434,2388,1644,1302,1542,425,306,1120,2159,264,393,1930,322,2977,998,469,1444,1786,427,1548,1219,105,522,1942,67,1684,746,1738,430,323,490,1554,1687,74,226... | -0.4382834749199662,-0.4382834749199662,-0.37966711166030426,0.038526658332115674,-0.5275674680675104,-0.5880217491572218,-0.6492423972397605,-0.4088860728488319,0.5685132566383815,0.9579237536502591,-0.3217563066408477,0.9358878616746352,-0.0694704733838678,0.14413493056950505,-1.000530653277979,0.32349580032456454,2.... | 3,120 |
Phospholipid metabolism | 7 | 47 | 2.726316 | 0.006405 | P35790,O00459,Q9NPH0,Q8IV08,Q10713,Q8NCC3,Q9BVG9 | Processes and pathways | Reactome Pathways | msigdb_reactome | 0,156,5,39,105,21,85 | 2501,156,2924,1377,2208,2297,2018,2386,1032,1158,0,2338,2847,1162,3059,1821,2438,1086,2221,1786,105,586,2178,1796,39,1050,1232,1691,1837,21,868,894,1183,668,669,3102,1366,2819,2188,85,2047,5,181,2132,3000,1242,2199 | -0.6492423972397605,1.5362117181364128,-1.238060398252917,0.038526658332115674,-0.4382834749199662,-0.4976220214613302,-0.3217563066408477,-0.5576999615504026,0.24745340385816628,0.17017548246536693,5.899253810656477,-0.5275674680675104,-1.0672234487170145,0.17017548246536693,-1.9076504275094626,-0.20798764245173287,-0... | 3,120 |
Inner mitochondrial membrane protein complex | 25 | 76 | 2.723973 | 0.00645 | O75947,P21912,Q96CU9,O14949,P13073,O14925,Q9P0J0,Q9NX63,O60830,P00846,P36542,Q9UDW1,P22695,P14406,Q9Y4W6,Q13505,Q5XKP0,P14927,P24539,Q16891,Q96IX5,P20674,O75964,O96000,Q99623 | Localization | GO Cellular component | msigdb_gocc | 252,378,25,26,42,171,313,312,176,52,305,56,303,72,345,76,208,93,94,355,230,349,114,124,259 | 3109,1522,388,171,26,3070,2602,176,2909,2294,2505,464,1152,252,114,654,1711,984,2425,124,604,52,3087,422,1774,913,2383,2536,42,72,93,1388,2152,349,378,303,94,919,1342,2387,2513,519,305,1542,2575,955,2833,2927,2849,883,76,716,1002,355,841,586,208,1745,3085,750,526,25,230,259,595,2045,972,821,1324,312,313,56,1476,345,702... | -3.4883531035688655,-0.042241579625993585,0.8691530690352253,1.4775738794299105,3.459191262825689,-2.0696602571110043,-0.7425516146318213,1.4578623634759529,-1.2034112370325538,-0.4976220214613302,-0.6492423972397605,0.7786741122076469,0.17017548246536693,1.1517209730784248,1.818768282448762,0.5445741216866079,-0.15209... | 3,120 |
Phospholipid binding | 21 | 83 | 2.72287 | 0.006472 | O60313,Q13045,Q8NCC3,P53367,Q8WTV0,P21796,Q15286,Q9Y4G8,P50897,O60749,Q9NZD2,Q9UM22,O14773,Q14108,Q15075,Q9Y3E7,P45880,Q9BWH2,Q8N668,Q9Y2I1,Q9UJZ1 | Functions | GO Molecular function | msigdb_gomf | 389,522,21,284,28,160,540,168,51,420,320,65,66,67,324,203,454,216,475,225,512 | 1425,2501,978,66,1376,1199,1150,2620,389,1966,420,3062,2208,731,828,3002,1482,1483,1207,1156,2251,2384,830,2938,160,2574,2061,1923,568,454,1488,1439,1821,51,1442,284,684,1447,522,685,1170,1736,67,745,1047,1352,324,540,2787,1265,1095,475,21,2274,28,2076,1235,1008,1362,1366,1842,969,216,2047,1512,757,1104,320,2372,1665,1... | 0.011755338385683791,-0.6492423972397605,0.2729362763877655,2.385428384194839,0.038526658332115674,0.14413493056950505,0.17017548246536693,-0.7740586736982547,0.8691530690352253,-0.29306044672954845,0.8241310428665671,-1.947658572174278,-0.4382834749199662,0.47202132781882844,0.39833990773856,-1.4877287999834443,-0.015... | 3,120 |
Anion transmembrane transport | 7 | 41 | 2.720588 | 0.006517 | P08183,Q9UHG3,P41440,Q9Y277,Q9H2D1,P21796,P30825 | Processes and pathways | GO Biological process | msigdb_gobp | 64,8,73,79,61,160,63 | 1066,1967,1587,1628,550,2147,911,64,912,2808,2536,160,63,73,454,1876,2706,2397,808,2441,1594,2224,1350,2444,1224,779,2075,189,575,480,1102,61,1661,820,2766,797,8,602,79,1111,1196 | 0.22183326505174678,-0.29306044672954845,-0.0694704733838678,-0.09685523182921355,0.6630753264781283,-0.4088860728488319,0.32349580032456454,2.401552801979837,0.32349580032456454,-1.000530653277979,-0.6801459566044995,1.5362117181364128,2.449587253406975,2.3039419144770994,0.8014574420423553,-0.23617802356071166,-0.869... | 3,120 |
Tetrapyrrole binding | 9 | 15 | 2.708709 | 0.006755 | Q16850,Q6UW02,O00264,O43169,Q7KZN9,Q99707,Q96EY8,Q8WYQ5,P30519 | Functions | GO Molecular function | msigdb_gomf | 194,141,262,80,335,507,415,574,62 | 262,80,1774,770,1637,62,2160,194,141,335,574,415,507,620,944 | 1.1305797371850148,2.2042035774756688,-0.17996198897025922,0.4475879086837396,-0.09685523182921355,2.449587253406975,-0.4088860728488319,1.3781703257871583,1.6132609997025542,0.9579237536502591,0.6396116988763457,0.8466959209611702,0.7327741710393836,0.5923317961811347,0.32349580032456454 | 3,120 |
Regulation of mrna processing | 43 | 85 | 2.672668 | 0.007525 | Q12872,Q9UHX1,P51114,P38159,P52756,P62995,P84103,Q6PJT7,Q15007,Q9BWF3,Q08170,Q07021,O00422,P51116,Q9NWH9,P09012,P98179,O00267,Q9Y580,O75494,P98175,Q13247,Q9Y2W1,P61978,Q15637,P22626,Q8N7H5,Q14011,Q96ST2,Q6P1J9,Q16629,Q5VTR2,Q15427,Q13242,O75150,Q8N684,Q13573,P19338,Q13595,Q96MU7,Q96PU8,P26368,Q2TAY7 | Processes and pathways | GO Biological process | msigdb_gobp | 885,397,391,140,263,265,521,664,152,547,774,408,652,290,443,552,48,800,315,803,426,570,329,322,840,321,718,81,754,865,227,617,490,234,484,504,613,241,242,642,643,737,890 | 800,652,1585,1625,484,803,1480,1338,552,1339,1156,3039,2303,1635,2459,241,321,737,1033,2256,1871,140,920,1083,2467,391,290,263,1165,322,265,521,426,48,2660,408,1168,774,1936,2068,885,234,570,613,242,81,2036,1832,152,1452,1944,490,840,227,1353,890,3067,617,1135,865,1948,664,1309,2271,933,504,718,2185,2873,1566,642,643,2... | 0.42302785571210444,0.5445741216866079,-0.0694704733838678,-0.09685523182921355,0.75578003326324,0.42302785571210444,-0.015166862701093613,0.06514870608694326,0.6630753264781283,0.06514870608694326,0.17017548246536693,-1.712329994309814,-0.4976220214613302,-0.09685523182921355,-0.6185351182463072,1.2145771446757452,0.9... | 3,120 |
Positive regulation of rna splicing | 8 | 22 | 2.663022 | 0.007744 | Q9Y2W1,Q15427,P38159,P62995,Q14011,P98179,P19338,Q13595 | Processes and pathways | GO Biological process | msigdb_gobp | 329,490,140,265,81,48,241,242 | 2013,1338,1156,241,1390,737,2256,140,1165,265,48,2068,503,613,242,81,490,1182,1566,853,1666,329 | -0.3217563066408477,0.06514870608694326,0.17017548246536693,1.2145771446757452,0.038526658332115674,0.47202132781882844,-0.46786141367036915,1.6323249879473072,0.17017548246536693,1.1305797371850148,2.801929332566857,-0.35062453129738713,0.7327741710393836,0.5923317961811347,1.2145771446757452,2.2042035774756688,0.7557... | 3,120 |
mRNA splicing factor | 33 | 58 | 2.652269 | 0.007995 | Q8WXF1,P38159,P62995,P84103,Q15459,Q9BWF3,Q08170,Q92804,Q07955,Q8WWY3,P09012,P98179,O75494,Q13247,P33240,Q96PK6,Q15637,Q14011,Q12874,P35637,Q16629,P08579,Q13242,Q15233,Q8IWZ8,P19338,P09661,Q13595,Q96PU8,O43395,Q13243,P23246,Q15428 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 527,140,265,521,410,547,774,153,293,814,552,48,803,570,566,847,840,81,837,248,227,485,234,747,893,241,732,242,643,365,503,496,888 | 1623,365,2248,1585,803,1671,2295,2250,485,1338,552,732,241,496,566,248,140,2756,2066,1347,3046,265,521,48,923,1168,293,774,2068,885,837,234,503,570,242,81,1879,747,1452,2351,888,410,840,227,2611,893,1750,2271,814,527,153,847,643,547,1276,1412,2376,2923 | -0.09685523182921355,0.9137480795405156,-0.46786141367036915,-0.0694704733838678,0.42302785571210444,-0.12439757025387724,-0.4976220214613302,-0.46786141367036915,0.75578003326324,0.06514870608694326,0.6630753264781283,0.47202132781882844,1.2145771446757452,0.7327741710393836,0.6396116988763457,1.172767077784285,1.6323... | 3,120 |
Glycosyl compound catabolic process | 6 | 10 | 2.651378 | 0.008016 | Q9NUJ1,P36639,P06280,Q13126,P08236,P04066 | Processes and pathways | GO Biological process | msigdb_gobp | 167,135,232,20,247,282 | 2571,1070,1773,282,232,247,135,20,309,167 | -0.7112482098625537,0.22183326505174678,-0.17996198897025922,1.0880085580638097,1.2353427068536198,1.172767077784285,1.6702193073777245,3.7786917531689994,1.023417311456126,1.516747891198495 | 3,120 |
Corneal opacity | 13 | 55 | 2.646266 | 0.008139 | P02545,O43505,P10619,Q15056,P51648,Q16625,Q13510,O96028,P06280,P08236,P04066,P16278,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 376,34,58,323,91,266,44,347,232,247,282,283,123 | 2088,1289,34,2247,2423,2845,1528,2014,1906,1907,123,1588,2621,909,347,376,1773,282,232,247,2624,58,283,2460,2305,2388,1159,1035,91,1084,2160,2030,998,1786,500,406,1942,44,2661,323,1453,1653,266,1455,1308,1997,1884,671,1107,1324,2597,2669,1371,1286,1028 | -0.37966711166030426,0.0916230653837448,3.1697972893617217,-0.46786141367036915,-0.5880217491572218,-1.0672234487170145,-0.042241579625993585,-0.3217563066408477,-0.2645349940023304,-0.2645349940023304,1.763620063558507,-0.0694704733838678,-0.7740586736982547,0.32349580032456454,0.9358878616746352,0.8915034664671595,-0... | 3,120 |
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