term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abnormality of head blood vessel
| 7
| 23
| 2.753876
| 0.005889
|
P17900,Q13510,P16278,Q9NZJ7,P21964,P10619,P00846
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
68,21,117,216,92,91,61
|
2222,885,2692,61,1023,252,608,91,2181,117,68,2941,92,2158,1275,2635,2050,21,1057,1390,216,2820,484
|
-0.5198580262786188,0.314435910199321,-0.8229719076907467,2.879803953814494,0.17025670420391295,1.4912946822328113,0.628061558250135,2.4374031190390943,-0.4929810145479234,2.241752275250984,2.7800795662254263,-1.1260105908189355,2.4374031190390943,-0.4795833493036897,-0.026905183599894182,-0.7808058429070066,-0.42626214908149684,3.1073290564690894,0.1459248602176856,-0.08972406297560863,1.6105455839468559,-0.9367611784117341,0.8514366183973154
| 3,120
|
Glycosphingolipid metabolic process
| 6
| 9
| 2.747899
| 0.005998
|
P06280,P17900,Q99805,P16278,Q9NZD2,P06865
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
159,68,197,117,184,252
|
275,159,252,608,117,68,2028,197,184
|
1.4005070484783886,1.9472674467092672,1.4912946822328113,0.628061558250135,2.241752275250984,2.7800795662254263,-0.4129986202657584,1.6889376731850534,1.7664679945101098
| 3,120
|
golgi
| 27
| 66
| 2.743792
| 0.006073
|
Q9Y487,Q8NBN3,P61026,Q9UM00,P61019,Q9NTJ5,Q15907,Q9Y3E0,Q9UI14,Q13190,Q9NR31,Q8IXU6,O15127,Q8TAD4,Q15904,Q9H0U4,Q8N6T3,O15258,P53367,P49755,O15126,Q8IZA0,Q96A49,Q9BXB4,Q9Y371,Q5VW38,O75787
|
Localization
|
OpenCell Localization
|
opencell_localization
|
130,31,516,396,648,399,23,416,154,540,432,303,49,179,192,321,592,583,715,213,727,605,474,736,364,114,501
|
1220,2039,1083,1398,1021,727,49,583,2176,501,2256,928,1035,1529,2668,821,2608,2159,741,1966,213,715,2995,2635,1503,2351,648,516,1573,802,2812,1130,1454,540,902,1431,1555,192,23,114,3074,303,605,592,31,179,1579,2298,999,474,736,321,1285,1852,432,399,1290,1082,2642,154,396,364,416,1207,130,2532
|
0.010505671581950045,-0.42626214908149684,0.12150490797103468,-0.10235882830439685,0.17025670420391295,0.49045228472298324,3.051107534962201,0.6620352061775991,-0.4929810145479234,0.8183900031612562,-0.533337616964219,0.2667168001795272,0.158101752015416,-0.16589304761576545,-0.8088863866647676,0.3736162256132579,-0.7668105367504043,-0.4795833493036897,0.4672450365868581,-0.38655086787023707,1.6302255513335107,0.5020263274235438,-1.2603375383129658,-0.7808058429070066,-0.15313781603736049,-0.5875327673192509,0.582499249500083,0.7962704004189698,-0.19147680577398604,0.3971446149576911,-0.9367611784117341,0.08470823190970675,-0.12770013664497198,0.7518164632462099,0.30253761226112147,-0.11501748631498755,-0.1786726765570447,1.7471650667426148,3.1073290564690894,2.286688869567451,-1.6328601175463011,1.2879196145694298,0.6394048579900791,0.6620352061775991,3.1073290564690894,1.8049164509564872,-0.19147680577398604,-0.5468447617435744,0.19450113637357203,0.8624169951839001,0.4788585457441188,1.2257336786097104,-0.026905183599894182,-0.3208887425169809,0.9387936429122186,1.0143344206282272,-0.026905183599894182,0.13372594148942707,-0.7808058429070066,2.003418073325324,1.0250588936033453,1.11026194950554,0.9820608618699915,0.03533096386757563,2.1510241118925633,-0.6972780863213089
| 3,120
|
Poor eye contact
| 9
| 37
| 2.740079
| 0.006142
|
Q5XKP0,Q86Y39,Q9UHX1,Q9P0J0,Q96CU9,Q9Y6M9,O96000,Q15907,Q8IUX1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
132,170,240,143,48,80,180,23,223
|
3107,1770,577,1423,1127,425,180,2199,2071,2569,2984,1970,920,1115,1198,707,2190,23,1845,1178,132,170,223,1955,48,2034,1351,1392,2583,1370,1436,245,470,1186,143,240,80
|
-2.3244806247371206,-0.29480442366640136,0.6733223906940821,-0.11501748631498755,0.08470823190970675,0.9496358869067834,1.795323913719972,-0.5064058663136635,-0.43955226841481043,-0.7389091550000886,-1.2302452877439438,-0.38655086787023707,0.2786781386912482,0.09699614240690609,0.03533096386757563,0.5135807473198399,-0.4929810145479234,3.1073290564690894,-0.3208887425169809,0.04770930716017372,2.141887659699094,1.8906694939515276,1.5809220421218821,-0.37336641310163715,3.067214874831629,-0.4129986202657584,-0.06452581499784397,-0.08972406297560863,-0.7389091550000886,-0.07711309132908688,-0.11501748631498755,1.5212977725567718,0.8733798938179188,0.04770930716017372,2.068372036315107,1.54122881436266,2.6449491417397626
| 3,120
|
Cristae formation
| 9
| 10
| 2.738302
| 0.006176
|
Q96E52,Q6UXV4,Q5XKP0,Q9BUR5,Q16891,O95202,Q9NX63,Q9NVH1,Q9Y512
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
225,195,132,165,210,282,443,542,323
|
282,210,132,195,225,165,542,443,594,323
|
1.369980905900342,1.640044944107091,2.141887659699094,1.6986756619645358,1.5809220421218821,1.9095856653720285,0.7518164632462099,0.927934341607611,0.6620352061775991,1.2257336786097104
| 3,120
|
P-type ATPase, phosphorylation site [IPR018303]
| 7
| 8
| 2.736048
| 0.006218
|
P16615,P98194,P20020,P05023,Q04656,Q9HD20,P35670
|
Sequence
|
InterPro PTM
|
interpro_ptm
|
160,289,388,201,398,149,342
|
201,160,388,430,342,289,398,149
|
1.6596427578574324,1.9472674467092672,1.04645811026075,0.9387936429122186,1.1734842794897706,1.3393208461533432,1.0143344206282272,2.022036880868175
| 3,120
|
P-type ATPase, haloacid dehalogenase domain [IPR044492]
| 7
| 8
| 2.736048
| 0.006218
|
P16615,P98194,P20020,P05023,Q04656,Q9HD20,P35670
|
Sequence
|
InterPro Domain
|
interpro_domain
|
160,289,388,201,398,149,342
|
201,160,388,430,342,289,398,149
|
1.6596427578574324,1.9472674467092672,1.04645811026075,0.9387936429122186,1.1734842794897706,1.3393208461533432,1.0143344206282272,2.022036880868175
| 3,120
|
P-type ATPase [IPR001757]
| 7
| 8
| 2.736048
| 0.006218
|
P16615,P98194,P20020,P05023,Q04656,Q9HD20,P35670
|
Sequence
|
InterPro Family
|
interpro_family
|
160,289,388,201,398,149,342
|
201,160,388,430,342,289,398,149
|
1.6596427578574324,1.9472674467092672,1.04645811026075,0.9387936429122186,1.1734842794897706,1.3393208461533432,1.0143344206282272,2.022036880868175
| 3,120
|
P-type ATPase, transmembrane domain superfamily [IPR023298]
| 7
| 8
| 2.736048
| 0.006218
|
P16615,P98194,P20020,P05023,Q04656,Q9HD20,P35670
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
160,289,388,201,398,149,342
|
201,160,388,430,342,289,398,149
|
1.6596427578574324,1.9472674467092672,1.04645811026075,0.9387936429122186,1.1734842794897706,1.3393208461533432,1.0143344206282272,2.022036880868175
| 3,120
|
P-type ATPase, cytoplasmic domain N [IPR023299]
| 7
| 8
| 2.736048
| 0.006218
|
P16615,P98194,P20020,P05023,Q04656,Q9HD20,P35670
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
160,289,388,201,398,149,342
|
201,160,388,430,342,289,398,149
|
1.6596427578574324,1.9472674467092672,1.04645811026075,0.9387936429122186,1.1734842794897706,1.3393208461533432,1.0143344206282272,2.022036880868175
| 3,120
|
P-type ATPase, A domain superfamily [IPR008250]
| 7
| 8
| 2.736048
| 0.006218
|
P16615,P98194,P20020,P05023,Q04656,Q9HD20,P35670
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
160,289,388,201,398,149,342
|
201,160,388,430,342,289,398,149
|
1.6596427578574324,1.9472674467092672,1.04645811026075,0.9387936429122186,1.1734842794897706,1.3393208461533432,1.0143344206282272,2.022036880868175
| 3,120
|
Vacuolar membrane
| 34
| 114
| 2.734439
| 0.006249
|
Q9Y487,O15400,Q96GC9,Q16625,O15118,P04062,P11279,O15260,O95772,P11117,Q8NF37,Q14108,Q07065,P42785,Q92542,Q9UIQ6,Q9NY64,O75503,Q15043,O95721,Q9NZJ7,Q93050,P20645,P10619,P42892,Q8WTV0,P13473,Q8IV08,Q8NCG7,Q9Y371,P10253,Q9P253,P51790,Q9Y6I9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
130,134,265,268,141,275,278,285,7,8,162,22,20,46,174,185,189,64,334,204,216,88,344,91,93,101,228,106,362,364,365,375,369,122
|
2512,3017,141,285,134,2566,1337,1100,728,2588,64,501,629,2515,204,7,2921,275,1425,1862,2152,675,1830,1864,1035,365,91,8,1628,278,228,344,1427,2981,2835,1699,931,741,2047,871,508,1998,46,93,1835,1721,954,369,854,1700,2351,1197,648,823,1871,2826,1657,617,1747,2812,1919,20,2373,1873,22,334,268,957,946,106,391,362,162,922,101,3058,2453,174,88,2104,2031,730,265,2215,776,2250,864,848,576,1184,2086,1438,3037,1264,725,895,189,216,1353,1290,375,1855,1618,185,2968,1963,807,451,1493,1063,364,559,130,122
|
-0.6972780863213089,-1.3514648583892033,2.068372036315107,1.3597758294429656,2.132739507118012,-0.7389091550000886,-0.06452581499784397,0.10926167126011344,0.49045228472298324,-0.7528450205022053,2.8632777541578998,0.8183900031612562,0.6053183644197377,-0.6972780863213089,1.6498506656784873,3.1073290564690894,-1.081846393052922,1.4005070484783886,-0.11501748631498755,-0.3339693636833012,-0.4795833493036897,0.5596036536159662,-0.3208887425169809,-0.3339693636833012,0.158101752015416,1.0996686756577085,2.4374031190390943,3.1073290564690894,-0.21715898005436454,1.3903464678842952,1.5710197329219444,1.1629871131431153,-0.11501748631498755,-1.2302452877439438,-0.9655209099750421,-0.2558686053497298,0.2667168001795272,0.4672450365868581,-0.42626214908149684,0.32631335668396794,0.8073390961220606,-0.3997615651907241,3.083286891375091,2.4286244658647527,-0.3208887425169809,-0.2688219354682781,0.24273050882000022,1.0890591952246833,0.33817003194732587,-0.2558686053497298,-0.5875327673192509,0.03533096386757563,0.582499249500083,0.3736162256132579,-0.3339693636833012,-0.9511251967557256,-0.23003723432961226,0.6166994167264761,-0.28180050541945734,-0.9367611784117341,-0.36020808645859054,3.1073290564690894,-0.6011513795208029,-0.3339693636833012,3.1073290564690894,1.1944311691364766,1.4207840447832099,0.24273050882000022,0.2547342844462805,2.34913092241935,1.04645811026075,1.11026194950554,1.9190248758612094,0.2786781386912482,2.3757265160314076,-1.5062692780273925,-0.642176835766896,1.862200304747472,2.5246065738795194,-0.4528690958405845,-0.4129986202657584,0.49045228472298324,1.4309005541628823,-0.5064058663136635,0.4322851425823638,-0.5198580262786188,0.33817003194732587,0.35000601574553336,0.6845910055704713,0.04770930716017372,-0.43955226841481043,-0.11501748631498755,-1.4284010971851733,-0.014411717321070097,0.5020263274235438,0.314435910199321,1.7568231217436605,1.6105455839468559,-0.06452581499784397,-0.026905183599894182,1.0890591952246833,-0.3208887425169809,-0.20430553885186603,1.7664679945101098,-1.1853677536639942,-0.37336641310163715,0.3971446149576911,0.9170579238372758,-0.1404068795755925,0.1459248602176856,1.11026194950554,0.7182861013625904,2.1510241118925633,2.2236984308409684
| 3,120
|
mitochondria
| 7
| 10
| 2.723886
| 0.006452
|
Q15388,P45880,Q9NR31,O95140,Q9Y277,P21796,Q969Q5
|
Localization
|
OpenCell Localization
|
opencell_localization
|
352,15,432,495,44,11,58
|
1449,495,11,15,1457,352,58,432,542,44
|
-0.12770013664497198,0.8294231843173793,3.1073290564690894,3.1073290564690894,-0.12770013664497198,1.1419450738425903,2.92915905420511,0.9387936429122186,0.7518164632462099,3.1073290564690894
| 3,120
|
Hydrogen ion transport
| 7
| 19
| 2.723461
| 0.00646
|
Q9Y487,P24539,Q93050,P56385,P00846,O75964,Q15904
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
130,12,88,348,61,6,192
|
660,6,61,458,1427,2981,12,1273,801,741,2047,1999,1479,348,1871,192,88,1618,130
|
0.5710610469198908,3.1073290564690894,2.879803953814494,0.8952535006860544,-0.11501748631498755,-1.2302452877439438,3.1073290564690894,-0.026905183599894182,0.3971446149576911,0.4672450365868581,-0.42626214908149684,-0.3997615651907241,-0.1404068795755925,1.1524740622552163,-0.3339693636833012,1.7471650667426148,2.5246065738795194,-0.20430553885186603,2.1510241118925633
| 3,120
|
Metal ion homeostasis
| 44
| 82
| 2.722509
| 0.006479
|
Q8N668,Q9Y487,O75027,P20020,Q9UM00,Q04656,Q9HD20,O75880,P55011,Q9Y6N1,O95202,P05026,P16615,P98194,P02792,P30519,P23634,Q8TAD4,Q9H3K6,O60826,Q15904,P04899,Q9Y4W6,P05023,Q15043,Q6P4Q7,Q16891,P51572,Q96TC7,P35670,O43819,Q9BPX6,Q8NE86,P07686,Q9Y5X3,Q9UJZ1,P09601,P54709,O76024,Q96HE7,P02786,Q8WWC4,Q96A33,Q8IYU8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
511,130,131,388,396,398,149,273,783,404,282,661,160,289,552,13,430,179,316,695,192,705,594,201,334,465,210,339,340,342,217,351,481,608,235,766,113,748,244,636,630,764,125,641
|
2512,3017,217,2149,695,131,273,3060,244,282,928,630,552,1887,705,201,661,1598,608,2152,1269,113,2261,851,160,2555,2415,388,2200,430,2954,2497,2963,13,1801,342,2047,2646,339,1949,748,783,1091,1871,1236,955,289,2801,398,2400,2576,2463,1074,334,2211,192,210,465,1754,1927,641,511,796,481,179,764,125,824,636,960,340,351,1081,2216,316,149,766,396,130,594,235,404
|
-0.6972780863213089,-1.3514648583892033,1.6006849247164414,-0.4795833493036897,0.5251156174631679,2.141887659699094,1.4005070484783886,-1.5219569468598286,1.5212977725567718,1.369980905900342,0.2667168001795272,0.6053183644197377,0.7294811048241373,-0.34707577428405895,0.5135807473198399,1.6596427578574324,0.5710610469198908,-0.20430553885186603,0.628061558250135,-0.4795833493036897,-0.026905183599894182,2.286688869567451,-0.533337616964219,0.33817003194732587,1.9472674467092672,-0.7250028020839093,-0.6284732846345887,1.04645811026075,-0.5064058663136635,0.9387936429122186,-1.1704774288251414,-0.6834594520783637,-1.1853677536639942,3.1073290564690894,-0.30783379939432337,1.1734842794897706,-0.42626214908149684,-0.7948310791463405,1.1839656140069246,-0.37336641310163715,0.45561168292170245,0.42059180507154753,0.12150490797103468,-0.3339693636833012,-0.0019414638218673386,0.24273050882000022,1.3393208461533432,-0.9224287018087298,1.0143344206282272,-0.6147981757408897,-0.7389091550000886,-0.6559089596214692,0.13372594148942707,1.1944311691364766,-0.5064058663136635,1.7471650667426148,1.640044944107091,0.8843253753961765,-0.28180050541945734,-0.36020808645859054,0.593918331939264,0.8073390961220606,0.40887832137263497,0.8514366183973154,1.8049164509564872,0.44395840998636554,2.187453572170523,0.3736162256132579,0.6053183644197377,0.24273050882000022,1.1839656140069246,1.1524740622552163,0.13372594148942707,-0.5064058663136635,1.236136635275694,2.022036880868175,0.44395840998636554,1.0250588936033453,2.1510241118925633,0.6620352061775991,1.5611034542199569,1.0035932957279798
| 3,120
|
Endoplasmic reticulum golgi intermediate compartment
| 25
| 50
| 2.720815
| 0.006512
|
Q15363,Q96GC9,P61019,Q9Y3A6,Q13190,O15260,Q10472,P80303,Q969X5,Q02818,Q12907,Q5BJH7,Q7Z7H5,P24390,Q15904,Q9H0U4,O15258,P51572,Q9Y282,P49755,O95070,Q9BVK6,Q14789,O75396,Q9Y3B3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
136,265,648,415,540,285,163,18,681,19,688,183,699,62,192,321,583,339,84,213,215,624,633,627,379
|
2039,583,285,1623,627,215,768,1269,62,2497,942,3097,697,213,1276,339,2798,782,1776,648,18,19,1454,163,688,540,633,1782,136,192,183,2485,699,1230,2298,2772,681,3083,265,1120,624,321,1587,2642,2548,84,415,379,2532,1377
|
-0.42626214908149684,0.6620352061775991,1.3597758294429656,-0.21715898005436454,0.6053183644197377,1.6105455839468559,0.4322851425823638,-0.026905183599894182,2.879803953814494,-0.6834594520783637,0.2547342844462805,-1.927226968449506,0.5251156174631679,1.6302255513335107,-0.026905183599894182,1.1839656140069246,-0.9224287018087298,0.42059180507154753,-0.29480442366640136,0.582499249500083,3.1073290564690894,3.1073290564690894,-0.12770013664497198,1.9095856653720285,0.5366310104853638,0.7518164632462099,0.6053183644197377,-0.29480442366640136,2.123579621130263,1.7471650667426148,1.7664679945101098,-0.6696697876094331,0.5251156174631679,0.010505671581950045,-0.5468447617435744,-0.8938577669791549,0.5596036536159662,-1.7294767969392169,1.4309005541628823,0.09699614240690609,0.6166994167264761,1.2257336786097104,-0.19147680577398604,-0.7808058429070066,-0.7111258245859526,2.559195032678293,0.9820608618699915,1.0784334535521216,-0.6972780863213089,-0.07711309132908688
| 3,120
|
Hyperlipidemia
| 10
| 30
| 2.720368
| 0.006521
|
P06280,P50416,P22830,P38571,O95470,O75844,Q9UJS0,P23786,P50402,Q96MF7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
159,161,69,229,105,90,311,155,156,288
|
2222,1295,357,90,105,560,159,2258,69,155,839,1400,663,2745,229,697,156,161,2925,901,2075,2581,2545,1348,861,817,288,475,311,1138
|
-0.5198580262786188,-0.039421957943272905,1.120839071139155,2.4374031190390943,2.34913092241935,0.7070727943770848,1.9472674467092672,-0.533337616964219,2.7800795662254263,1.9940903702899961,0.35000601574553336,-0.10235882830439685,0.5710610469198908,-0.8796190081405505,1.5710197329219444,0.5251156174631679,1.9940903702899961,1.9472674467092672,-1.081846393052922,0.30253761226112147,-0.43955226841481043,-0.7389091550000886,-0.7111258245859526,-0.06452581499784397,0.33817003194732587,0.3853906088485544,1.3495558255696736,0.8624169951839001,1.2672525814950062,0.08470823190970675
| 3,120
|
Glycosyl compound catabolic process
| 7
| 10
| 2.715887
| 0.00661
|
P06280,Q9NUJ1,Q9BTY2,P36639,P00813,P04062,P04066
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
159,133,300,140,78,275,237
|
2949,78,275,237,159,353,140,1325,300,133
|
-1.1556212409978055,2.687448357265577,1.4005070484783886,1.54122881436266,1.9472674467092672,1.1314000946481249,2.0776030242802497,-0.05196213624197448,1.3085255697617286,2.141887659699094
| 3,120
|
Amino acid transmembrane transport
| 12
| 14
| 2.712489
| 0.006678
|
P08195,O60831,O75746,Q9H9B4,P30825,Q15758,P05556,Q96NB2,Q9UJS0,Q15041,O75915,Q8TDW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
675,551,425,522,76,753,586,686,311,279,628,547
|
551,425,628,586,675,76,279,753,547,686,1787,777,522,311
|
0.7294811048241373,0.9496358869067834,0.6053183644197377,0.6620352061775991,0.5596036536159662,2.704378541877951,1.3903464678842952,0.45561168292170245,0.7406578703701303,0.5481269986020768,-0.29480442366640136,0.4322851425823638,0.7962704004189698,1.2672525814950062
| 3,120
|
Abnormal circulating cholesterol concentration
| 16
| 30
| 2.710888
| 0.00671
|
Q10471,Q9NVI7,O75845,P38571,O75431,Q15738,Q15800,Q15392,Q9UJS0,P02545,Q9NZJ7,Q9BTV4,Q9BV10,P37268,P50402,Q15904
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
707,231,347,229,357,651,239,402,311,560,216,475,346,218,156,192
|
357,347,560,2258,218,229,2646,2161,156,2519,934,842,1130,707,901,2075,708,402,651,239,192,2545,1348,475,346,1062,231,216,1588,311
|
1.120839071139155,1.1524740622552163,0.7070727943770848,-0.533337616964219,1.6006849247164414,1.5710197329219444,-0.7948310791463405,-0.4795833493036897,1.9940903702899961,-0.6972780863213089,0.2667168001795272,0.35000601574553336,0.08470823190970675,0.5135807473198399,0.30253761226112147,-0.43955226841481043,0.5135807473198399,1.0035932957279798,0.582499249500083,1.54122881436266,1.7471650667426148,-0.7111258245859526,-0.06452581499784397,0.8624169951839001,1.1629871131431153,0.1459248602176856,1.5710197329219444,1.6105455839468559,-0.19147680577398604,1.2672525814950062
| 3,120
|
Sphingolipid metabolism
| 7
| 11
| 2.707901
| 0.006771
|
P06280,Q13510,O95470,Q06136,P04062,P16278,O15269
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
159,21,105,401,275,117,280
|
981,280,1767,486,105,275,159,117,401,21,2089
|
0.20659078834565117,1.3801711028302934,-0.29480442366640136,0.8404387020294766,2.34913092241935,1.4005070484783886,1.9472674467092672,2.241752275250984,1.0035932957279798,3.1073290564690894,-0.43955226841481043
| 3,120
|
Poor head control
| 17
| 70
| 2.704396
| 0.006843
|
P13073,Q5XKP0,P17900,Q86Y39,Q9P0J0,Q96CU9,O95721,P21912,Q9Y6M9,O96000,Q14118,Q10713,P00374,Q9NPL8,Q9NZJ7,P06865,Q8IUX1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
9,132,68,170,143,48,204,178,80,180,370,54,309,245,216,252,223
|
3107,3017,963,2224,1770,577,1191,1423,2113,1127,2017,1338,204,180,309,560,1008,252,1009,9,68,2199,178,2982,2071,2157,2047,2537,3003,2423,2984,1655,920,2124,1115,2500,1344,1701,2812,1919,2130,2444,54,370,752,1243,1178,132,2212,170,223,1488,1705,48,1414,916,2385,1370,1436,777,245,1313,393,470,216,1186,143,2660,1188,80
|
-2.3244806247371206,-1.3514648583892033,0.23070539012934577,-0.5198580262786188,-0.29480442366640136,0.6733223906940821,0.03533096386757563,-0.11501748631498755,-0.46621274973913956,0.08470823190970675,-0.4129986202657584,-0.06452581499784397,1.6498506656784873,1.795323913719972,1.2672525814950062,0.7070727943770848,0.1823898035706314,1.4912946822328113,0.1823898035706314,3.1073290564690894,2.7800795662254263,-0.5064058663136635,1.8049164509564872,-1.2302452877439438,-0.43955226841481043,-0.4795833493036897,-0.42626214908149684,-0.7111258245859526,-1.2905705747567982,-0.6284732846345887,-1.2302452877439438,-0.23003723432961226,0.2786781386912482,-0.46621274973913956,0.09699614240690609,-0.6834594520783637,-0.06452581499784397,-0.2558686053497298,-0.9367611784117341,-0.36020808645859054,-0.46621274973913956,-0.642176835766896,2.9944511899123603,1.0890591952246833,0.45561168292170245,-0.0019414638218673386,0.04770930716017372,2.141887659699094,-0.5064058663136635,1.8906694939515276,1.5809220421218821,-0.1404068795755925,-0.2558686053497298,3.067214874831629,-0.10235882830439685,0.29061838215713776,-0.6011513795208029,-0.07711309132908688,-0.11501748631498755,0.4322851425823638,1.5212977725567718,-0.039421957943272905,1.0357667713484127,0.8733798938179188,1.6105455839468559,0.04770930716017372,2.068372036315107,-0.7948310791463405,0.04770930716017372,2.6449491417397626
| 3,120
|
Hormone metabolic process
| 10
| 27
| 2.704013
| 0.006851
|
Q8NBN7,P05023,P16435,O95470,Q9HB40,Q8TAD4,P30536,O75844,P42892,Q53GQ0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
169,201,298,105,50,179,338,90,93,255
|
2150,501,90,105,201,2154,2781,298,338,93,2974,943,2724,2619,255,709,169,1412,179,1214,636,2385,50,1264,1588,1735,386
|
-0.4795833493036897,0.8183900031612562,2.4374031190390943,2.34913092241935,1.6596427578574324,-0.4795833493036897,-0.9081276149528227,1.3085255697617286,1.1839656140069246,2.4286244658647527,-1.2002923885824353,0.2547342844462805,-0.8512341644014038,-0.7668105367504043,1.4812650661362408,0.5135807473198399,1.9001338837009643,-0.10235882830439685,1.8049164509564872,0.022929782979047558,0.6053183644197377,-0.6011513795208029,3.034964700499758,-0.014411717321070097,-0.19147680577398604,-0.2688219354682781,1.0571329664420128
| 3,120
|
Apical plasma membrane
| 20
| 48
| 2.697837
| 0.006979
|
P41440,P20020,Q16625,Q04656,P55011,P05026,P08195,P23634,Q8TAD4,P08183,Q86UE4,P05023,P30825,Q15043,P36543,P54709,O75787,P51790,Q9Y6M7,O75955
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
508,388,268,398,783,661,675,430,179,190,199,201,76,334,741,748,501,369,506,629
|
1048,1696,1398,1793,1190,501,629,1268,201,661,190,675,2069,1830,1067,2720,1629,1946,388,1427,430,1891,76,1384,741,973,2047,508,369,1106,748,783,1871,398,1116,812,334,1459,268,199,179,1079,1331,1787,893,1082,1446,506
|
0.1459248602176856,-0.2558686053497298,-0.10235882830439685,-0.30783379939432337,0.03533096386757563,0.8183900031612562,0.6053183644197377,-0.026905183599894182,1.6596427578574324,0.5710610469198908,1.7471650667426148,0.5596036536159662,-0.43955226841481043,-0.3208887425169809,0.13372594148942707,-0.8512341644014038,-0.21715898005436454,-0.37336641310163715,1.04645811026075,-0.11501748631498755,0.9387936429122186,-0.34707577428405895,2.704378541877951,-0.08972406297560863,0.4672450365868581,0.21865884469902433,-0.42626214908149684,0.8073390961220606,1.0890591952246833,0.10926167126011344,0.45561168292170245,0.42059180507154753,-0.3339693636833012,1.0143344206282272,0.09699614240690609,0.3853906088485544,1.1944311691364766,-0.12770013664497198,1.4207840447832099,1.6791862202916965,1.8049164509564872,0.13372594148942707,-0.05196213624197448,-0.29480442366640136,0.314435910199321,0.13372594148942707,-0.11501748631498755,0.8183900031612562
| 3,120
|
Nucleotide transport
| 10
| 12
| 2.695588
| 0.007026
|
P12236,P41440,P12235,Q6NUK1,Q8TB61,Q9H2D1,Q08722,Q9HC21,O43808,Q8TDW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
609,508,579,390,200,36,206,373,529,547
|
529,729,579,609,508,206,390,200,547,1331,36,373
|
0.774079390173673,0.49045228472298324,0.6733223906940821,0.628061558250135,0.8073390961220606,1.6498506656784873,1.04645811026075,1.6791862202916965,0.7406578703701303,-0.05196213624197448,3.1073290564690894,1.0890591952246833
| 3,120
|
Bulbar signs
| 6
| 12
| 2.692342
| 0.007095
|
Q99720,Q15043,P04062,Q9NZJ7,P35637,P00846
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,334,275,216,405,61
|
486,61,1023,275,1008,405,853,334,861,35,216,1317
|
0.8404387020294766,2.879803953814494,0.17025670420391295,1.4005070484783886,0.1823898035706314,0.9928354619075869,0.33817003194732587,1.1944311691364766,0.33817003194732587,3.1073290564690894,1.6105455839468559,-0.039421957943272905
| 3,120
|
Limb ataxia
| 8
| 27
| 2.687221
| 0.007205
|
O14773,Q9NW15,Q14108,Q8IV08,P04062,Q10713,P07196,O75298
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,258,22,106,275,54,186,5
|
2277,0,1793,5,275,2553,186,2259,3063,1271,2157,2890,508,1090,54,684,22,106,2545,1435,1332,1436,322,258,835,1735,594
|
-0.5468447617435744,3.1073290564690894,-0.30783379939432337,3.1073290564690894,1.4005070484783886,-0.7250028020839093,1.7568231217436605,-0.533337616964219,-1.5376831048205557,-0.026905183599894182,-0.4795833493036897,-1.0379803402121284,0.8073390961220606,0.12150490797103468,2.9944511899123603,0.5481269986020768,3.1073290564690894,2.34913092241935,-0.7111258245859526,-0.11501748631498755,-0.05196213624197448,-0.11501748631498755,1.2257336786097104,1.4712210819843028,0.3618213873624192,-0.2688219354682781,0.6620352061775991
| 3,120
|
Inorganic anion transport
| 14
| 24
| 2.686097
| 0.007229
|
P08183,Q9NW15,O43681,Q4KMQ2,P45880,Q15043,Q9UHG3,Q9Y277,Q9UBX3,P30536,P51790,P21796,Q9Y6M7,Q8TDW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
190,258,486,634,15,334,43,44,83,338,369,11,506,547
|
2301,486,190,639,11,338,15,369,2823,783,1072,784,334,634,2380,547,1081,756,258,83,43,44,3098,506
|
-0.5603795848494529,0.8404387020294766,1.7471650667426148,0.593918331939264,3.1073290564690894,1.1839656140069246,3.1073290564690894,1.0890591952246833,-0.9511251967557256,0.42059180507154753,0.13372594148942707,0.42059180507154753,1.1944311691364766,0.6053183644197377,-0.6011513795208029,0.7406578703701303,0.13372594148942707,0.45561168292170245,1.4712210819843028,2.559195032678293,3.1073290564690894,3.1073290564690894,-1.9945391164615682,0.8183900031612562
| 3,120
|
Protein transmembrane import into intracellular organelle
| 7
| 12
| 2.684114
| 0.007272
|
Q15388,O75381,O95831,Q3ZCQ8,O96008,O14925,O60830
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
352,387,332,407,502,59,4
|
59,539,1624,4,387,1449,332,502,2153,352,407,1286
|
2.912744419090262,0.7518164632462099,-0.21715898005436454,3.1073290564690894,1.04645811026075,-0.12770013664497198,1.1944311691364766,0.8183900031612562,-0.4795833493036897,1.1419450738425903,0.9928354619075869,-0.026905183599894182
| 3,120
|
Phospholipid metabolic process
| 21
| 74
| 2.677687
| 0.007413
|
Q9UG56,Q9NPH0,Q9NTJ5,O95749,Q99623,Q92643,Q86YN1,O15269,Q96N66,Q8NF37,Q9BVG9,Q10713,Q9NX62,Q8NHP8,P35790,O95674,Q9NZC3,P37268,Q8WTV0,Q5H8A4,Q8NCC3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
267,37,399,144,146,403,147,280,290,162,176,54,55,63,194,444,207,218,101,233,120
|
3065,2808,456,1083,1941,280,1767,1794,2476,1169,444,144,2939,2780,608,645,2044,2415,2608,2972,194,218,1319,1402,3003,1275,1970,1196,2649,1130,2028,54,3089,2448,233,844,987,1367,794,147,814,2407,1058,120,162,63,735,101,816,804,403,817,290,623,564,146,1120,1247,864,176,1371,1561,37,2433,399,582,55,2089,207,1290,267,2548,766,1317
|
-1.5534479602974562,-0.9367611784117341,0.8952535006860544,0.12150490797103468,-0.37336641310163715,1.3801711028302934,-0.29480442366640136,-0.30783379939432337,-0.6696697876094331,0.04770930716017372,0.9170579238372758,2.0498741203070034,-1.1260105908189355,-0.9081276149528227,0.628061558250135,0.582499249500083,-0.42626214908149684,-0.6284732846345887,-0.7668105367504043,-1.2002923885824353,1.6986756619645358,1.6006849247164414,-0.05196213624197448,-0.10235882830439685,-1.2905705747567982,-0.026905183599894182,-0.38655086787023707,0.03533096386757563,-0.7948310791463405,0.08470823190970675,-0.4129986202657584,2.9944511899123603,-1.8111255729851865,-0.642176835766896,1.5611034542199569,0.35000601574553336,0.20659078834565117,-0.07711309132908688,0.40887832137263497,2.022036880868175,0.3853906088485544,-0.6147981757408897,0.1459248602176856,2.2327310420192736,1.9190248758612094,2.871545537278681,0.4788585457441188,2.3757265160314076,0.3853906088485544,0.3971446149576911,1.0035932957279798,0.3853906088485544,1.3393208461533432,0.6166994167264761,0.7070727943770848,2.031328055456678,0.09699614240690609,-0.0019414638218673386,0.33817003194732587,1.8526851103515125,-0.07711309132908688,-0.1786726765570447,3.1073290564690894,-0.6284732846345887,1.0143344206282272,0.6733223906940821,2.986321497503092,-0.43955226841481043,1.6498506656784873,-0.026905183599894182,1.4309005541628823,-0.7111258245859526,0.44395840998636554,-0.039421957943272905
| 3,120
|
Regulation of steroid biosynthetic process
| 6
| 11
| 2.675235
| 0.007468
|
Q13510,P05023,P16435,O94905,P30536,Q12770
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
21,201,298,331,338,286
|
424,331,201,298,338,286,21,1281,2384,1588,1648
|
0.9496358869067834,1.1944311691364766,1.6596427578574324,1.3085255697617286,1.1839656140069246,1.3597758294429656,3.1073290564690894,-0.026905183599894182,-0.6011513795208029,-0.19147680577398604,-0.21715898005436454
| 3,120
|
Endoplasmic reticulum lumen
| 23
| 58
| 2.673941
| 0.007497
|
Q9NWM8,Q8TED1,Q5JRA6,Q07065,Q02818,Q9BTY2,P13674,O00584,Q13217,P27824,O75718,O14657,O43852,Q8NBJ7,Q14257,Q9BV10,Q9BTV4,O43681,Q9NZ08,Q32P28,O43493,O76024,Q14118
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
393,394,545,20,19,300,435,312,445,324,578,337,341,597,87,346,475,486,359,232,242,244,370
|
312,884,337,242,486,341,1141,578,244,1714,768,2980,2934,1531,435,1399,851,1946,2183,740,2497,324,1383,822,2118,942,1276,782,3100,19,20,445,370,87,1875,1782,679,232,545,1611,938,913,1433,597,2103,394,2772,845,636,475,300,346,393,1587,359,1395,1218,1940
|
1.2568960359855035,0.314435910199321,1.1839656140069246,1.531270365709735,0.8404387020294766,1.1734842794897706,0.07239784971023856,0.6733223906940821,1.5212977725567718,-0.2688219354682781,0.4322851425823638,-1.2302452877439438,-1.1112557890025987,-0.16589304761576545,0.927934341607611,-0.10235882830439685,0.33817003194732587,-0.37336641310163715,-0.4929810145479234,0.4672450365868581,-0.6834594520783637,1.215315149662245,-0.08972406297560863,0.3736162256132579,-0.46621274973913956,0.2547342844462805,-0.026905183599894182,0.42059180507154753,-2.0797011567697794,3.1073290564690894,3.1073290564690894,0.9170579238372758,1.0890591952246833,2.5246065738795194,-0.3339693636833012,-0.29480442366640136,0.5596036536159662,1.5611034542199569,0.7406578703701303,-0.20430553885186603,0.2667168001795272,0.29061838215713776,-0.11501748631498755,0.6507293845573393,-0.4528690958405845,1.0250588936033453,-0.8938577669791549,0.35000601574553336,0.6053183644197377,0.8624169951839001,1.3085255697617286,1.1629871131431153,1.0357667713484127,-0.19147680577398604,1.120839071139155,-0.08972406297560863,0.022929782979047558,-0.36020808645859054
| 3,120
|
Intrinsic component of mitochondrial outer membrane
| 8
| 11
| 2.670258
| 0.007579
|
Q15388,Q8TB36,Q9BWH2,Q9GZY8,O95140,P57105,O96008,P50416
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
352,642,166,336,495,118,502,161
|
1449,495,502,161,118,352,1283,642,166,336,674
|
-0.12770013664497198,0.8294231843173793,0.8183900031612562,1.9472674467092672,2.241752275250984,1.1419450738425903,-0.026905183599894182,0.593918331939264,1.9095856653720285,1.1944311691364766,0.5710610469198908
| 3,120
|
Glycerophospholipid metabolic process
| 16
| 54
| 2.668756
| 0.007613
|
Q96N66,Q8NF37,O95674,P35790,Q8WTV0,Q9UG56,Q5H8A4,Q9NPH0,Q9NZC3,Q9NTJ5,Q9BVG9,Q99623,Q92643,Q10713,Q9NX62,Q8NCC3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
290,162,444,194,101,267,233,37,207,399,176,146,403,54,55,120
|
3065,2808,456,1083,1941,1794,1169,444,2939,2780,2044,2415,2972,194,1319,1402,3003,1275,1970,1130,54,233,844,987,1367,794,814,2407,1058,120,162,735,101,816,804,403,817,290,623,564,146,1247,864,176,1371,1561,37,399,582,55,2089,207,267,766
|
-1.5534479602974562,-0.9367611784117341,0.8952535006860544,0.12150490797103468,-0.37336641310163715,-0.30783379939432337,0.04770930716017372,0.9170579238372758,-1.1260105908189355,-0.9081276149528227,-0.42626214908149684,-0.6284732846345887,-1.2002923885824353,1.6986756619645358,-0.05196213624197448,-0.10235882830439685,-1.2905705747567982,-0.026905183599894182,-0.38655086787023707,0.08470823190970675,2.9944511899123603,1.5611034542199569,0.35000601574553336,0.20659078834565117,-0.07711309132908688,0.40887832137263497,0.3853906088485544,-0.6147981757408897,0.1459248602176856,2.2327310420192736,1.9190248758612094,0.4788585457441188,2.3757265160314076,0.3853906088485544,0.3971446149576911,1.0035932957279798,0.3853906088485544,1.3393208461533432,0.6166994167264761,0.7070727943770848,2.031328055456678,-0.0019414638218673386,0.33817003194732587,1.8526851103515125,-0.07711309132908688,-0.1786726765570447,3.1073290564690894,1.0143344206282272,0.6733223906940821,2.986321497503092,-0.43955226841481043,1.6498506656784873,1.4309005541628823,0.44395840998636554
| 3,120
|
Proximal muscle weakness
| 25
| 63
| 2.668217
| 0.007626
|
Q99720,Q8TB36,Q9H9S5,P35637,P50402,Q8NI60,Q13510,Q9BQT8,Q13501,Q86U42,P21912,P02545,P07196,P00846,P12235,O60313,P35670,Q9BTV4,Q9BPX6,P13473,P10253,P22626,O95140,Q8TD16,Q14118
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,642,657,405,156,546,21,296,684,685,178,560,186,61,579,203,342,475,351,228,365,496,495,371,370
|
2040,203,1191,495,928,61,560,2414,1008,186,1863,1298,365,2834,579,228,2555,869,178,2835,496,2157,405,342,973,1601,156,1302,1105,781,920,1090,2327,2540,2130,1325,1604,684,21,2075,370,3022,2675,1606,698,1610,685,2545,2959,546,642,371,1348,861,1392,35,351,296,475,1332,657,2221,971
|
-0.42626214908149684,1.6498506656784873,0.03533096386757563,0.8294231843173793,0.2667168001795272,2.879803953814494,0.7070727943770848,-0.6284732846345887,0.1823898035706314,1.7568231217436605,-0.3339693636833012,-0.039421957943272905,1.0996686756577085,-0.9655209099750421,0.6733223906940821,1.5710197329219444,-0.7250028020839093,0.32631335668396794,1.8049164509564872,-0.9655209099750421,0.8294231843173793,-0.4795833493036897,0.9928354619075869,1.1734842794897706,0.21865884469902433,-0.20430553885186603,1.9940903702899961,-0.039421957943272905,0.10926167126011344,0.42059180507154753,0.2786781386912482,0.12150490797103468,-0.5739422113824679,-0.7111258245859526,-0.46621274973913956,-0.05196213624197448,-0.20430553885186603,0.5481269986020768,3.1073290564690894,-0.43955226841481043,1.0890591952246833,-1.3514648583892033,-0.8088863866647676,-0.20430553885186603,0.5251156174631679,-0.20430553885186603,0.5481269986020768,-0.7111258245859526,-1.1704774288251414,0.7406578703701303,0.593918331939264,1.0890591952246833,-0.06452581499784397,0.33817003194732587,-0.08972406297560863,3.1073290564690894,1.1524740622552163,1.318805766980325,0.8624169951839001,-0.05196213624197448,0.582499249500083,-0.5064058663136635,0.23070539012934577
| 3,120
|
Intrinsic component of golgi membrane
| 10
| 11
| 2.663902
| 0.007724
|
O43505,P98194,Q6ZRP7,Q969X5,Q8TB61,L0R6Q1,O15258,Q9Y282,Q5BJH7,O95070
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
96,289,480,681,200,330,583,84,183,215
|
330,583,96,215,289,707,183,480,200,681,84
|
1.1944311691364766,0.6620352061775991,2.4022241001142395,1.6105455839468559,1.3393208461533432,0.5135807473198399,1.7664679945101098,0.8514366183973154,1.6791862202916965,0.5596036536159662,2.559195032678293
| 3,120
|
Lipase activity
| 8
| 19
| 2.658595
| 0.007847
|
P38571,Q9H6V9,Q8NCG7,Q8IV08,Q9NZC3,P09601,Q8NCC3,Q8NHP8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
229,74,362,106,207,113,120,63
|
2567,2093,113,2415,2972,2118,229,106,814,413,2407,1058,120,362,63,74,2089,207,1377
|
-0.7389091550000886,-0.4528690958405845,2.286688869567451,-0.6284732846345887,-1.2002923885824353,-0.46621274973913956,1.5710197329219444,2.34913092241935,0.3853906088485544,0.9820608618699915,-0.6147981757408897,0.1459248602176856,2.2327310420192736,1.11026194950554,2.871545537278681,2.7633251516522725,-0.43955226841481043,1.6498506656784873,-0.07711309132908688
| 3,120
|
Mitochondrial transmembrane transport
| 25
| 49
| 4.355429
| 0.000013
|
P00846,P21796,O60830,P24539,Q8IYU8,O75964,O14925,Q9UJZ1,O95831,P25705,P06576,P23786,O75027,O43772,Q9BPX6,O75947,Q6P4A7,Q3ZCQ8,Q9H2D1,Q9Y4W6,Q9BQT8,O43615,Q15388,Q9UJS0,P56385
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
7,8,14,523,145,15,149,543,24,533,156,159,161,39,67,570,456,329,76,211,467,584,485,490,126
|
149,584,39,14,161,1648,982,570,15,1426,964,1961,24,912,7,2605,156,1545,2256,2657,8,159,523,533,624,2105,1682,2769,2628,126,2163,485,329,456,145,693,1092,1247,1722,1070,67,467,76,1605,1673,1229,490,543,211
|
1.8104905344165125,0.6836796028570836,2.8849739127891,3.662148863096418,1.7462892988618541,-0.16178387178475653,0.2885413384136224,0.6984707313156334,3.570223146966479,-0.030300711303461843,0.30413037071405097,-0.34649940710130533,3.2454831822206605,0.35070324111746226,3.813122404253874,-0.8026462174024811,1.772033110463191,-0.09574924303379817,-0.5360007060205642,-0.8571770657812502,3.813122404253874,1.7591718093586464,0.7719957292272027,0.7573477339359754,0.6391316883481546,-0.4320264666261241,-0.17838548918434077,-0.967495404620523,-0.8207773259856875,1.974991705363492,-0.46651989752259204,0.8448142839802352,1.1432677072413866,0.8881725845149391,1.8360241868746086,0.5642956462857995,0.21010374774524396,0.09888373702173922,-0.1950246665788902,0.2258574389042269,2.44886013744723,0.8737472783538901,2.3658651509983173,-0.12869256222156378,-0.16178387178475653,0.11487460343449528,0.8448142839802352,0.7573477339359754,1.5106857256113622
| 3,120
|
Intrinsic component of mitochondrial membrane
| 20
| 46
| 3.901448
| 0.000096
|
Q9Y2R0,O43819,P57105,O60830,Q9NX63,O14925,Q53H12,Q15070,Q9Y6N1,Q13505,Q16891,O75431,Q5XKP0,Q9BPX6,Q6P4A7,Q9Y4W6,Q9GZY8,Q15388,Q9BWH2,O95140
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,514,264,14,148,149,536,170,303,47,316,313,578,67,456,211,604,485,617,481
|
149,514,14,313,608,1426,481,1961,912,2256,1988,1186,1682,264,2163,47,170,485,1133,316,536,578,456,1273,1897,693,1444,1722,1070,67,1252,2343,617,604,1981,1673,808,2091,810,148,1331,1373,0,211,2225,303
|
1.8104905344165125,0.786615468427979,3.662148863096418,1.1849686248979059,0.6540102092830856,-0.030300711303461843,0.8448142839802352,-0.34649940710130533,0.35070324111746226,-0.5360007060205642,-0.3635249182132702,0.13083109947309807,-0.17838548918434077,1.33596472752481,-0.46651989752259204,2.7384264660489417,1.6815558467757523,0.8448142839802352,0.17849600673831648,1.1849686248979059,0.7573477339359754,0.6984707313156334,0.8881725845149391,0.0828583342496927,-0.2956592676299645,0.5642956462857995,-0.030300711303461843,-0.1950246665788902,0.2258574389042269,2.44886013744723,0.09888373702173922,-0.5885504992892956,0.6540102092830856,0.6688594713374666,-0.34649940710130533,-0.16178387178475653,0.4582592999615156,-0.41484073446716224,0.4582592999615156,1.8232677727408004,0.05070324943423878,0.018407995915568375,4.674789402306948,1.5106857256113622,-0.5011773922472554,1.226444230698108
| 3,120
|
Protein targeting to mitochondrion
| 18
| 48
| 3.657093
| 0.000255
|
P49840,Q9Y5J9,Q8N4H5,O95140,P55786,Q3ZCQ8,Q9P0J0,Q9NS69,O43464,O60830,Q10713,O43615,O14925,Q5JRX3,O95831,Q53H12,O14737,Q15388
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,461,90,481,42,329,371,77,389,14,238,584,149,410,24,536,95,485
|
908,1060,95,149,389,584,14,2073,1648,1426,481,2279,24,912,1588,1545,2135,659,2732,1164,131,917,42,2057,238,485,1927,329,536,410,2426,90,1444,1250,1449,1156,604,1500,1229,77,371,2669,762,1910,1727,2225,461,2071
|
0.35070324111746226,0.2258574389042269,2.209394294309303,1.8104905344165125,1.0167852644421618,0.6836796028570836,3.662148863096418,-0.41484073446716224,-0.16178387178475653,-0.030300711303461843,0.8448142839802352,-0.5534751015591063,3.2454831822206605,0.35070324111746226,-0.12869256222156378,-0.09574924303379817,-0.44925278266923796,0.594319275549686,-0.9305339680832876,0.14675338988725495,1.9373348286481238,0.35070324111746226,2.851390894707872,-0.3976953730192357,1.3901468727742385,0.8448142839802352,-0.312566785682029,1.1432677072413866,0.7573477339359754,0.9741550117257047,-0.6414835578447224,2.2699410728253326,-0.030300711303461843,0.09888373702173922,-0.030300711303461843,0.16264163820366534,0.6688594713374666,-0.06295244245028012,0.11487460343449528,2.3658651509983173,1.0591788621121219,-0.8571770657812502,0.5038867309618552,-0.2956592676299645,-0.1950246665788902,-0.5011773922472554,0.8881725845149391,-0.3976953730192357
| 3,120
|
EF-hand domain pair [IPR011992]
| 23
| 48
| 3.590002
| 0.000331
|
P46939,P80303,Q15293,Q14257,Q8IYU8,Q96AY3,Q9UPN3,Q02818,Q9NWM8,Q9UBV8,Q03001,Q9BPX6,O43852,O43707,Q99653,P12814,Q9UJS0,Q9H4M9,Q13813,Q96D71,Q9H8M7,Q9BRK5,Q99584
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
637,3,265,9,145,271,661,30,32,442,573,67,70,569,330,585,490,618,227,230,115,246,252
|
569,70,888,982,964,2300,585,3070,666,2443,1886,1620,2838,2509,1462,987,637,1242,2306,3,30,573,227,9,2541,265,749,1386,1839,1897,145,845,804,271,1447,230,252,330,67,246,1073,618,115,32,2346,442,490,661
|
0.6984707313156334,2.41339669379397,0.3661632883154021,0.2885413384136224,0.30413037071405097,-0.570991623394744,0.6836796028570836,-1.791706727074942,0.5793224179068317,-0.6592141662818555,-0.2956592676299645,-0.14521962532452135,-1.079538114927136,-0.7126680845484551,-0.046608532900190375,0.2885413384136224,0.6242237793066672,0.09888373702173922,-0.570991623394744,3.912265751114164,3.1270818699928937,0.6984707313156334,1.4170960559577421,3.793150878054305,-0.7305742271780316,1.33596472752481,0.5038867309618552,0.002207377438801204,-0.2619608096795884,-0.2956592676299645,1.8360241868746086,0.42768619226574317,0.4582592999615156,1.322359527263043,-0.030300711303461843,1.4170960559577421,1.3631033438829987,1.1432677072413866,2.44886013744723,1.37663694769063,0.2258574389042269,0.6540102092830856,2.062163025553647,3.0726884314042517,-0.5885504992892956,0.9169413951198621,0.8448142839802352,0.594319275549686
| 3,120
|
Negative regulation of mrna metabolic process
| 19
| 45
| 3.494293
| 0.000475
|
P67809,P61978,P50750,Q9Y2W1,P35637,Q13242,O75494,O75150,Q14011,O60506,P22626,P07910,Q99729,Q16629,P38159,Q07021,Q92804,Q14103,P98175
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,255,151,549,174,183,554,434,56,187,193,344,221,357,103,233,113,377,376
|
2252,1376,1456,187,434,554,1100,344,1211,1078,2784,193,1104,1795,174,103,151,255,130,376,2724,233,1521,1969,2662,1409,1109,183,859,56,377,1323,785,1552,357,600,1950,954,1388,2583,113,221,1303,1306,549
|
-0.5360007060205642,0.002207377438801204,-0.046608532900190375,1.5900158562501612,0.9169413951198621,0.7132329833227257,0.1943166566085935,1.101338722336577,0.11487460343449528,0.21010374774524396,-0.9860478230479183,1.5768503245839907,0.1943166566085935,-0.24516947172325332,1.6424561771136268,2.136121609666896,1.7976923957350528,1.3495459683507376,1.9499071826655876,1.0450737766397848,-0.9121244013006663,1.4036332115706927,-0.07933261901370642,-0.34649940710130533,-0.8571770657812502,-0.014028799969153467,0.1943166566085935,1.6162802105485474,0.4123527679415628,2.554314581480143,1.0450737766397848,0.05070324943423878,0.47349926724163727,-0.09574924303379817,1.0732579772137116,0.6688594713374666,-0.3295134311551762,0.3196869315450229,0.002207377438801204,-0.766520239175899,2.062163025553647,1.443951626246411,0.06679822788517814,0.06679822788517814,0.7426713601480582
| 3,120
|
Cation transmembrane transporter activity
| 26
| 75
| 3.248585
| 0.00116
|
P00846,P24539,O75964,Q00535,P00403,P06576,Q15043,P30825,O43772,Q70HW3,Q9HD20,Q8TAD4,Q13423,P98194,P16615,Q93050,Q93034,Q7KZN9,Q9Y487,Q9UDW1,P13073,O14548,Q8N4V1,Q6P4Q7,P56385,P36543
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
7,523,15,154,276,156,417,35,39,46,55,448,60,446,444,79,335,465,88,93,98,479,120,380,126,373
|
479,39,2007,570,15,964,276,7,1544,1077,2605,156,1064,1050,1182,1005,1569,1711,2256,98,444,890,684,1650,1887,1184,523,533,35,2302,767,624,373,1432,1654,2105,1768,868,2628,126,1683,2956,446,2163,154,732,60,417,1468,1660,380,1661,46,465,120,693,448,2545,335,79,1070,2909,1583,1473,2221,1605,1673,2091,55,737,93,828,959,88,850
|
0.8448142839802352,2.8849739127891,-0.3805901708428884,0.6984707313156334,3.570223146966479,0.30413037071405097,1.3087302728453603,3.813122404253874,-0.09574924303379817,0.21010374774524396,-0.8026462174024811,1.772033110463191,0.2258574389042269,0.24157788767834681,0.13083109947309807,0.27291968269656813,-0.11220249635179408,-0.1950246665788902,-0.5360007060205642,2.172842799903386,0.902570585002106,0.3661632883154021,0.5642956462857995,-0.16178387178475653,-0.2956592676299645,0.13083109947309807,0.7719957292272027,0.7573477339359754,3.0179282568081494,-0.570991623394744,0.48870836441780346,0.6391316883481546,1.0450737766397848,-0.030300711303461843,-0.16178387178475653,-0.4320264666261241,-0.2284164650375626,0.3969879056771085,-0.8207773259856875,1.974991705363492,-0.17838548918434077,-1.3090459546983426,0.902570585002106,-0.46651989752259204,1.7848732800962697,0.5190345053695938,2.51931754717366,0.9598918250269893,-0.046608532900190375,-0.16178387178475653,1.0450737766397848,-0.16178387178475653,2.7724824566536013,0.8737472783538901,2.01246909431283,0.5642956462857995,0.902570585002106,-0.7305742271780316,1.1293168573183845,2.353937773187976,0.2258574389042269,-1.1933666554371067,-0.11220249635179408,-0.046608532900190375,-0.5011773922472554,-0.12869256222156378,-0.16178387178475653,-0.41484073446716224,2.60074042050876,0.5190345053695938,2.233668543940409,0.44298832212023614,0.3196869315450229,2.281995142154195,0.42768619226574317
| 3,120
|
Mitochondrial transport
| 34
| 83
| 3.201295
| 0.001368
|
P49840,P00846,O60830,P24539,O75964,O43464,O14925,Q9UJZ1,O95831,Q5JRX3,Q53H12,P25705,P06576,P23786,O43772,Q15070,P55786,P45880,O75431,Q9Y5J9,O75947,Q96EK5,Q3ZCQ8,Q9NS69,O43615,Q9GZY8,Q8N4H5,O14737,Q15388,Q9UJS0,O95140,Q9P0J0,Q10713,P56385
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,7,14,523,15,389,149,543,24,410,536,533,156,159,39,170,42,45,313,461,570,458,329,77,584,604,90,95,485,490,481,371,238,126
|
908,1060,95,149,389,584,39,14,2073,313,1648,570,15,1426,481,2279,24,912,7,1732,2605,156,1588,1963,1545,2256,2135,159,523,533,2955,2281,659,2732,624,2185,45,2105,2532,1164,131,702,1682,917,1360,42,2628,126,2057,238,170,485,1927,329,536,410,1386,2426,1897,90,1444,1247,458,1071,1250,1449,1156,604,1500,1229,77,371,2669,761,762,490,543,2434,1910,1727,2225,461,2071
|
0.35070324111746226,0.2258574389042269,2.209394294309303,1.8104905344165125,1.0167852644421618,0.6836796028570836,2.8849739127891,3.662148863096418,-0.41484073446716224,1.1849686248979059,-0.16178387178475653,0.6984707313156334,3.570223146966479,-0.030300711303461843,0.8448142839802352,-0.5534751015591063,3.2454831822206605,0.35070324111746226,3.813122404253874,-0.21170159451326637,-0.8026462174024811,1.772033110463191,-0.12869256222156378,-0.34649940710130533,-0.09574924303379817,-0.5360007060205642,-0.44925278266923796,1.7591718093586464,0.7719957292272027,0.7573477339359754,-1.3090459546983426,-0.5534751015591063,0.594319275549686,-0.9305339680832876,0.6391316883481546,-0.483828027884879,2.7838025090073337,-0.4320264666261241,-0.7305742271780316,0.14675338988725495,1.9373348286481238,0.5492388269345314,-0.17838548918434077,0.35070324111746226,0.018407995915568375,2.851390894707872,-0.8207773259856875,1.974991705363492,-0.3976953730192357,1.3901468727742385,1.6815558467757523,0.8448142839802352,-0.312566785682029,1.1432677072413866,0.7573477339359754,0.9741550117257047,0.002207377438801204,-0.6414835578447224,-0.2956592676299645,2.2699410728253326,-0.030300711303461843,0.09888373702173922,0.8881725845149391,0.2258574389042269,0.09888373702173922,-0.030300711303461843,0.16264163820366534,0.6688594713374666,-0.06295244245028012,0.11487460343449528,2.3658651509983173,1.0591788621121219,-0.8571770657812502,0.5038867309618552,0.5038867309618552,0.8448142839802352,0.7573477339359754,-0.6414835578447224,-0.2956592676299645,-0.1950246665788902,-0.5011773922472554,0.8881725845149391,-0.3976953730192357
| 3,120
|
Organelle fusion
| 23
| 52
| 3.165803
| 0.001547
|
P06493,Q9H6R6,Q9Y3E7,Q8N2A8,Q9NX63,Q9UJZ1,Q9BZG1,O60499,Q9Y6C9,Q9UQN3,O95249,Q96E52,Q9Y4W6,O95721,P31751,Q9GZY8,O95140,O60313,O15400,Q9P253,Q12981,Q15075,Q9NQG6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,519,266,269,148,543,164,295,698,582,314,594,211,81,206,604,481,480,607,107,492,364,513
|
2855,1879,607,2226,480,1647,295,817,1821,481,314,833,81,819,1856,129,1050,1885,206,1767,2981,2055,2511,1192,492,838,364,2426,692,1090,269,1444,594,1355,1724,164,604,1451,1500,519,513,1503,148,107,1202,543,1909,1453,582,266,211,698
|
-1.1172794037264824,-0.2956592676299645,0.6540102092830856,-0.5185682109135206,0.8448142839802352,-0.16178387178475653,1.2402198321498792,0.44298832212023614,-0.2619608096795884,0.8448142839802352,1.1849686248979059,0.42768619226574317,2.34199247904662,0.44298832212023614,-0.2787906755702021,1.9499071826655876,0.24157788767834681,-0.2956592676299645,1.5106857256113622,-0.2284164650375626,-1.3872274349331235,-0.3976953730192357,-0.7126680845484551,0.13083109947309807,0.8303063613261049,0.42768619226574317,1.0591788621121219,-0.6414835578447224,0.5642956462857995,0.21010374774524396,1.322359527263043,-0.030300711303461843,0.6836796028570836,0.03457322912919779,-0.1950246665788902,1.72046033576955,0.6688594713374666,-0.030300711303461843,-0.06295244245028012,0.786615468427979,0.8012070731266786,-0.06295244245028012,1.8232677727408004,2.1238431973235943,0.13083109947309807,0.7573477339359754,-0.2956592676299645,-0.030300711303461843,0.6984707313156334,1.33596472752481,1.5106857256113622,0.5642956462857995
| 3,120
|
Inner mitochondrial membrane protein complex
| 35
| 76
| 3.131535
| 0.001739
|
P00846,Q96CU9,O60830,P24539,Q8IYU8,O75964,P22695,P14406,Q9NX63,O14925,Q53H12,P00403,P25705,P06576,Q96IX5,Q13505,O95168,O14949,Q16891,O75431,Q5XKP0,O96000,Q9BPX6,O75947,Q3ZCQ8,Q9Y4W6,Q9UDW1,P13073,O14548,O95169,Q9P0J0,Q99623,Q9Y6M9,P14927,P56385
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
7,141,14,523,145,15,401,19,148,149,536,276,533,156,426,47,555,58,316,313,578,65,67,570,329,211,93,98,479,609,371,630,632,249,126
|
3093,2410,479,149,58,2930,1336,14,2803,878,1758,313,738,570,15,555,609,1677,2204,65,276,7,2299,156,1569,1428,1711,2657,98,19,249,1312,2182,684,717,401,523,533,2207,2381,2302,948,624,1988,1654,2105,3036,2304,2628,126,47,1147,1947,316,329,536,578,1273,1053,145,693,141,426,630,67,2343,1229,810,1357,148,371,93,2434,211,2225,632
|
-2.243291875020247,-0.6414835578447224,0.8448142839802352,1.8104905344165125,2.51931754717366,-1.2509707594161343,0.03457322912919779,3.662148863096418,-1.0232974504893133,0.38159146097785057,-0.2284164650375626,1.1849686248979059,0.5038867309618552,0.6984707313156334,3.570223146966479,0.7132329833227257,0.6540102092830856,-0.17838548918434077,-0.5011773922472554,2.44886013744723,1.3087302728453603,3.813122404253874,-0.570991623394744,1.772033110463191,-0.11220249635179408,-0.030300711303461843,-0.1950246665788902,-0.8571770657812502,2.172842799903386,3.4042217306899554,1.3631033438829987,0.05070324943423878,-0.483828027884879,0.5642956462857995,0.534151825170032,1.0026016209135598,0.7719957292272027,0.7573477339359754,-0.5011773922472554,-0.623796233913705,-0.570991623394744,0.3196869315450229,0.6391316883481546,-0.3635249182132702,-0.16178387178475653,-0.4320264666261241,-1.5663663822078633,-0.570991623394744,-0.8207773259856875,1.974991705363492,2.7384264660489417,0.16264163820366534,-0.3295134311551762,1.1849686248979059,1.1432677072413866,0.7573477339359754,0.6984707313156334,0.0828583342496927,0.24157788767834681,1.8360241868746086,0.5642956462857995,1.8614748450901437,0.9456019017002357,0.6391316883481546,2.44886013744723,-0.5885504992892956,0.11487460343449528,0.4582592999615156,0.03457322912919779,1.8232677727408004,1.0591788621121219,2.233668543940409,-0.6414835578447224,1.5106857256113622,-0.5011773922472554,0.6391316883481546
| 3,120
|
Protein localization
| 26
| 70
| 3.089544
| 0.002005
|
P51648,P21796,O60830,Q9NX63,O14925,Q5JRX3,Q13011,P06576,A8MXV4,Q9Y2Q3,Q13505,P40855,O75431,Q9Y5J9,Q15067,Q3ZCQ8,Q9NS69,P50402,Q9NR77,P46379,Q8N4H5,O75381,Q9BY49,Q15388,O43765,Q10713
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
132,8,14,148,149,410,28,156,155,302,47,437,313,461,328,329,77,212,85,217,90,219,350,485,353,238
|
155,979,149,1281,831,584,665,353,2007,1511,14,219,2796,313,1648,1162,982,2482,1426,609,912,156,1569,2925,1007,1545,2256,2657,1618,8,966,533,2157,1431,1988,437,217,212,132,1126,3068,1595,238,28,838,47,328,485,329,410,3079,90,803,1444,2634,1842,2842,350,1229,85,77,148,1782,2827,490,2434,302,2225,461,2071
|
1.772033110463191,0.2885413384136224,1.8104905344165125,0.06679822788517814,0.42768619226574317,0.6836796028570836,0.5793224179068317,1.0732579772137116,-0.3805901708428884,-0.07933261901370642,3.662148863096418,1.4573445331488604,-1.0046484114833856,1.1849686248979059,-0.16178387178475653,0.14675338988725495,0.2885413384136224,-0.6948061890014895,-0.030300711303461843,0.6540102092830856,0.35070324111746226,1.772033110463191,-0.11220249635179408,-1.231717470627754,0.27291968269656813,-0.09574924303379817,-0.5360007060205642,-0.8571770657812502,-0.14521962532452135,3.813122404253874,0.30413037071405097,0.7573477339359754,-0.46651989752259204,-0.030300711303461843,-0.3635249182132702,0.9169413951198621,1.4840610389071347,1.497384815530289,1.9373348286481238,0.17849600673831648,-1.7709185436163724,-0.12869256222156378,1.3901468727742385,3.159544170978448,0.42768619226574317,2.7384264660489417,1.1432677072413866,0.8448142839802352,1.1432677072413866,0.9741550117257047,-1.8754851855410017,2.2699410728253326,0.4582592999615156,-0.030300711303461843,-0.8207773259856875,-0.2619608096795884,-1.079538114927136,1.0873112286222568,0.11487460343449528,2.306048494162799,2.3658651509983173,1.8232677727408004,-0.2284164650375626,-1.0419952231737202,0.8448142839802352,-0.6414835578447224,1.226444230698108,-0.5011773922472554,0.8881725845149391,-0.3976953730192357
| 3,120
|
Protein kinase, ATP binding site [IPR017441]
| 20
| 47
| 3.055228
| 0.002249
|
P06493,P49840,Q99640,O75116,Q00536,Q9P289,P50750,Q00535,P24941,Q15375,P27361,P54646,P51812,Q13464,P31751,Q7KZI7,Q13555,Q13557,Q16513,Q15418
|
Sequence
|
InterPro Binding site
|
interpro_binding_site
|
129,131,654,521,18,542,151,154,31,671,551,423,172,189,206,472,356,493,626,127
|
2795,2348,521,1823,2047,129,983,1287,1916,2135,31,551,1407,206,1796,2353,1547,2054,1738,131,702,2907,151,172,2284,423,154,18,2645,1864,1218,1361,189,356,493,784,671,127,626,1552,472,2248,654,2802,1672,1160,542
|
-1.0046484114833856,-0.606151958922442,0.7719957292272027,-0.2619608096795884,-0.3976953730192357,1.9499071826655876,0.2885413384136224,0.06679822788517814,-0.312566785682029,-0.44925278266923796,3.105368151447201,0.7279664846318218,-0.014028799969153467,1.5106857256113622,-0.24516947172325332,-0.606151958922442,-0.09574924303379817,-0.3976953730192357,-0.21170159451326637,1.9373348286481238,0.5492388269345314,-1.1933666554371067,1.7976923957350528,1.6555112222855055,-0.5534751015591063,0.9456019017002357,1.7848732800962697,3.4460375576629554,-0.8389541891155845,-0.2787906755702021,0.11487460343449528,0.018407995915568375,1.5900158562501612,1.0732579772137116,0.8303063613261049,0.47349926724163727,0.5793224179068317,1.9624594510337707,0.6391316883481546,-0.09574924303379817,0.8592945504534439,-0.5185682109135206,0.6092863520442148,-1.0046484114833856,-0.16178387178475653,0.16264163820366534,0.7573477339359754
| 3,120
|
Ion transport
| 20
| 55
| 3.002126
| 0.002681
|
P00846,P21796,P24539,O75964,P25705,P06576,Q15043,P45880,Q9Y277,Q8TAD4,P98194,P16615,Q9BPX6,O75947,Q93050,Q9Y487,Q15904,Q6P4Q7,P56385,P36543
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
7,8,523,15,533,156,417,45,319,448,446,444,67,570,79,88,244,380,126,373
|
2550,570,15,964,912,7,1544,1077,156,2940,444,890,1650,1887,8,1184,523,533,767,624,373,1432,45,2105,1768,2577,868,2628,126,1683,446,732,840,417,244,1660,2214,380,1661,591,693,448,995,79,1722,67,2683,999,2221,828,959,319,88,3076,850
|
-0.7485248627310643,0.6984707313156334,3.570223146966479,0.30413037071405097,0.35070324111746226,3.813122404253874,-0.09574924303379817,0.21010374774524396,1.772033110463191,-1.2702763896857583,0.902570585002106,0.3661632883154021,-0.16178387178475653,-0.2956592676299645,3.813122404253874,0.13083109947309807,0.7719957292272027,0.7573477339359754,0.48870836441780346,0.6391316883481546,1.0450737766397848,-0.030300711303461843,2.7838025090073337,-0.4320264666261241,-0.2284164650375626,-0.766520239175899,0.3969879056771085,-0.8207773259856875,1.974991705363492,-0.17838548918434077,0.902570585002106,0.5190345053695938,0.42768619226574317,0.9598918250269893,1.37663694769063,-0.16178387178475653,-0.5011773922472554,1.0450737766397848,-0.16178387178475653,0.6836796028570836,0.5642956462857995,0.902570585002106,0.2885413384136224,2.353937773187976,-0.1950246665788902,2.44886013744723,-0.8754462172552409,0.2885413384136224,-0.5011773922472554,0.44298832212023614,0.3196869315450229,1.1849686248979059,2.281995142154195,-1.8334699706989743,0.42768619226574317
| 3,120
|
Serine/threonine-protein kinase, active site [IPR008271]
| 19
| 47
| 2.953189
| 0.003145
|
P06493,P49840,Q99640,O75116,Q00536,P50750,Q00535,P24941,P27361,P54646,P51812,Q13464,O75962,P31751,Q7KZI7,Q13555,Q13557,Q16513,Q15418
|
Sequence
|
InterPro Active site
|
interpro_active_site
|
129,131,654,521,18,151,154,31,551,423,172,189,203,206,472,356,493,626,127
|
2795,816,2348,521,203,1883,129,983,1287,1916,2135,31,551,1407,206,1796,2353,2054,1738,131,702,2907,151,172,2284,423,154,18,2645,1864,1361,189,2082,969,356,493,784,127,626,472,2473,652,2248,654,2802,1672,1160
|
-1.0046484114833856,0.44298832212023614,-0.606151958922442,0.7719957292272027,1.523963856715977,-0.2956592676299645,1.9499071826655876,0.2885413384136224,0.06679822788517814,-0.312566785682029,-0.44925278266923796,3.105368151447201,0.7279664846318218,-0.014028799969153467,1.5106857256113622,-0.24516947172325332,-0.606151958922442,-0.3976953730192357,-0.21170159451326637,1.9373348286481238,0.5492388269345314,-1.1933666554371067,1.7976923957350528,1.6555112222855055,-0.5534751015591063,0.9456019017002357,1.7848732800962697,3.4460375576629554,-0.8389541891155845,-0.2787906755702021,0.018407995915568375,1.5900158562501612,-0.41484073446716224,0.30413037071405097,1.0732579772137116,0.8303063613261049,0.47349926724163727,1.9624594510337707,0.6391316883481546,0.8592945504534439,-0.6769882967991228,0.6092863520442148,-0.5185682109135206,0.6092863520442148,-1.0046484114833856,-0.16178387178475653,0.16264163820366534
| 3,120
|
Inorganic molecular entity transmembrane transporter activity
| 34
| 76
| 2.931067
| 0.003378
|
P00846,P21796,P24539,O75964,Q00535,P00403,P25705,P06576,Q15043,O43681,Q8NE86,P45880,P20674,Q9HD20,Q9Y277,Q8TAD4,Q13423,P98194,P16615,O75947,Q93050,Q93034,Q7KZN9,Q9Y487,Q9NW15,Q9UDW1,Q04656,P13073,O14548,P36542,Q8N4V1,Q6P4Q7,P56385,P36543
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
7,8,523,15,154,276,533,156,417,665,693,45,684,55,319,448,60,446,444,570,79,335,465,88,737,93,732,98,479,624,120,380,126,373
|
2550,479,665,570,15,964,276,7,1544,1077,2605,156,1064,1050,1182,1005,1569,2940,1711,2256,98,444,890,684,1650,1887,8,1184,523,533,2302,767,624,373,1432,45,1654,2105,1768,868,2628,126,1683,2956,446,2163,154,990,732,60,417,1660,2214,380,465,120,693,448,995,335,79,1449,1583,1473,2221,1605,55,737,761,93,828,959,319,88,3076,850
|
-0.7485248627310643,0.8448142839802352,0.5793224179068317,0.6984707313156334,3.570223146966479,0.30413037071405097,1.3087302728453603,3.813122404253874,-0.09574924303379817,0.21010374774524396,-0.8026462174024811,1.772033110463191,0.2258574389042269,0.24157788767834681,0.13083109947309807,0.27291968269656813,-0.11220249635179408,-1.2702763896857583,-0.1950246665788902,-0.5360007060205642,2.172842799903386,0.902570585002106,0.3661632883154021,0.5642956462857995,-0.16178387178475653,-0.2956592676299645,3.813122404253874,0.13083109947309807,0.7719957292272027,0.7573477339359754,-0.570991623394744,0.48870836441780346,0.6391316883481546,1.0450737766397848,-0.030300711303461843,2.7838025090073337,-0.16178387178475653,-0.4320264666261241,-0.2284164650375626,0.3969879056771085,-0.8207773259856875,1.974991705363492,-0.17838548918434077,-1.3090459546983426,0.902570585002106,-0.46651989752259204,1.7848732800962697,0.2885413384136224,0.5190345053695938,2.51931754717366,0.9598918250269893,-0.16178387178475653,-0.5011773922472554,1.0450737766397848,0.8737472783538901,2.01246909431283,0.5642956462857995,0.902570585002106,0.2885413384136224,1.1293168573183845,2.353937773187976,-0.030300711303461843,-0.11220249635179408,-0.046608532900190375,-0.5011773922472554,-0.12869256222156378,2.60074042050876,0.5190345053695938,0.5038867309618552,2.233668543940409,0.44298832212023614,0.3196869315450229,1.1849686248979059,2.281995142154195,-1.8334699706989743,0.42768619226574317
| 3,120
|
Protein localization to mitochondrion
| 19
| 60
| 2.777539
| 0.005477
|
P49840,O43464,O60830,O14925,Q5JRX3,O95831,Q53H12,Q15070,P55786,Q9Y5J9,Q3ZCQ8,Q9NS69,O43615,Q8N4H5,O14737,Q15388,O95140,Q9P0J0,Q10713
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,389,14,149,410,24,536,170,42,461,329,77,584,90,95,485,481,371,238
|
908,1060,2463,909,95,149,389,584,14,2073,1648,1426,481,2279,24,912,1588,1545,1210,2257,2135,2281,659,1430,2732,1164,131,917,1360,42,2057,238,170,485,1927,329,536,410,2426,90,1444,1247,1250,1449,1156,604,1500,1229,77,3042,371,2669,762,2434,1910,1727,2225,461,2071,698
|
0.35070324111746226,0.2258574389042269,-0.6769882967991228,0.35070324111746226,2.209394294309303,1.8104905344165125,1.0167852644421618,0.6836796028570836,3.662148863096418,-0.41484073446716224,-0.16178387178475653,-0.030300711303461843,0.8448142839802352,-0.5534751015591063,3.2454831822206605,0.35070324111746226,-0.12869256222156378,-0.09574924303379817,0.11487460343449528,-0.5360007060205642,-0.44925278266923796,-0.5534751015591063,0.594319275549686,-0.030300711303461843,-0.9305339680832876,0.14675338988725495,1.9373348286481238,0.35070324111746226,0.018407995915568375,2.851390894707872,-0.3976953730192357,1.3901468727742385,1.6815558467757523,0.8448142839802352,-0.312566785682029,1.1432677072413866,0.7573477339359754,0.9741550117257047,-0.6414835578447224,2.2699410728253326,-0.030300711303461843,0.09888373702173922,0.09888373702173922,-0.030300711303461843,0.16264163820366534,0.6688594713374666,-0.06295244245028012,0.11487460343449528,2.3658651509983173,-1.5865550545342373,1.0591788621121219,-0.8571770657812502,0.5038867309618552,-0.6414835578447224,-0.2956592676299645,-0.1950246665788902,-0.5011773922472554,0.8881725845149391,-0.3976953730192357,0.5642956462857995
| 3,120
|
EF-hand domain [IPR002048]
| 20
| 42
| 2.736677
| 0.006206
|
P80303,Q15293,Q14257,Q8IYU8,Q96AY3,Q9UPN3,Q02818,Q9NWM8,Q9UBV8,Q03001,Q9BPX6,O43852,O43707,Q99653,P12814,Q9UJS0,Q9H4M9,Q13813,Q96D71,Q9BRK5
|
Sequence
|
InterPro Domain
|
interpro_domain
|
3,265,9,145,271,661,30,32,442,573,67,70,569,330,585,490,618,227,230,246
|
569,70,888,982,964,2300,585,3070,666,2443,1886,1620,2838,2509,1462,987,1242,3,30,573,227,9,2541,265,749,1386,1897,145,804,271,1447,230,330,67,246,1073,618,32,2346,442,490,661
|
0.6984707313156334,2.41339669379397,0.3661632883154021,0.2885413384136224,0.30413037071405097,-0.570991623394744,0.6836796028570836,-1.791706727074942,0.5793224179068317,-0.6592141662818555,-0.2956592676299645,-0.14521962532452135,-1.079538114927136,-0.7126680845484551,-0.046608532900190375,0.2885413384136224,0.09888373702173922,3.912265751114164,3.1270818699928937,0.6984707313156334,1.4170960559577421,3.793150878054305,-0.7305742271780316,1.33596472752481,0.5038867309618552,0.002207377438801204,-0.2956592676299645,1.8360241868746086,0.4582592999615156,1.322359527263043,-0.030300711303461843,1.4170960559577421,1.1432677072413866,2.44886013744723,1.37663694769063,0.2258574389042269,0.6540102092830856,3.0726884314042517,-0.5885504992892956,0.9169413951198621,0.8448142839802352,0.594319275549686
| 3,120
|
Endoplasmic reticulum lumen
| 21
| 58
| 2.701452
| 0.006904
|
P30533,Q15293,Q14257,Q32P28,Q96AY3,P30040,Q13217,P13674,Q02818,Q9NWM8,O43681,P14314,P27361,Q9NZ08,Q8IXB1,Q07065,O43852,Q86UP2,Q9BTY2,P07237,O75718
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
263,265,9,139,271,534,157,414,30,32,665,666,551,176,323,68,70,602,370,623,241
|
1204,932,2481,1728,665,70,933,241,682,1004,623,2876,3038,1570,414,666,798,2103,2380,551,2104,1343,1407,534,1829,263,1291,1030,3060,30,68,157,2359,9,1716,1271,265,139,895,1629,602,323,1390,1039,2290,1601,2494,271,872,1810,370,1997,32,1330,176,1118,1257,1333
|
0.11487460343449528,0.3352111717576097,-0.6948061890014895,-0.21170159451326637,0.5793224179068317,2.41339669379397,0.3352111717576097,1.37663694769063,0.5642956462857995,0.27291968269656813,0.6391316883481546,-1.1552214493474031,-1.5865550545342373,-0.11220249635179408,0.9598918250269893,0.5793224179068317,0.4582592999615156,-0.4320264666261241,-0.623796233913705,0.7279664846318218,-0.4320264666261241,0.03457322912919779,-0.014028799969153467,0.7573477339359754,-0.2619608096795884,1.33596472752481,0.06679822788517814,0.2572652505088006,-1.7089228060787165,3.1270818699928937,2.4370565119015652,1.772033110463191,-0.606151958922442,3.793150878054305,-0.1950246665788902,0.0828583342496927,1.33596472752481,1.8868431098527443,0.3661632883154021,-0.14521962532452135,0.6688594713374666,1.1710934886626958,0.002207377438801204,0.2572652505088006,-0.5534751015591063,-0.12869256222156378,-0.6948061890014895,1.322359527263043,0.3969879056771085,-0.24516947172325332,1.0591788621121219,-0.3635249182132702,3.0726884314042517,0.05070324943423878,1.6424561771136268,0.1943166566085935,0.09888373702173922,0.05070324943423878
| 3,120
|
Nuclear envelope ne reassembly
| 21
| 51
| 2.692812
| 0.007085
|
P06493,Q9Y3E7,Q8IXJ6,Q9BTX1,Q92973,Q9BVA1,P57740,P42166,Q7Z3B4,P55735,Q9UQN3,Q8N1F7,P68371,P50402,Q86XL3,Q8NC56,P20700,Q13885,P02545,P37198,Q8NFH4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
129,266,33,546,695,564,304,686,308,438,582,190,704,212,101,368,231,747,119,499,642
|
2713,1338,119,1427,129,1617,2639,231,1516,499,686,768,2385,212,1216,1293,438,304,2630,1485,704,951,747,2389,1685,1746,308,101,33,190,368,1443,642,994,1093,2520,2650,1900,695,1556,2802,546,1015,564,1497,1998,1227,1909,582,1402,266
|
-0.9121244013006663,0.03457322912919779,2.01246909431283,-0.030300711303461843,1.9499071826655876,-0.14521962532452135,-0.8389541891155845,1.4036332115706927,-0.07933261901370642,0.8157706641011584,0.5642956462857995,0.48870836441780346,-0.623796233913705,1.497384815530289,0.11487460343449528,0.06679822788517814,0.9169413951198621,1.2126438954569019,-0.8207773259856875,-0.06295244245028012,0.5492388269345314,0.3196869315450229,0.5038867309618552,-0.623796233913705,-0.17838548918434077,-0.21170159451326637,1.198818726904989,2.1483809702874805,3.039876688867029,1.5900158562501612,1.0591788621121219,-0.030300711303461843,0.6242237793066672,0.2885413384136224,0.21010374774524396,-0.7126680845484551,-0.8389541891155845,-0.2956592676299645,0.5642956462857995,-0.09574924303379817,-1.0046484114833856,0.7426713601480582,0.27291968269656813,0.7132329833227257,-0.06295244245028012,-0.3635249182132702,0.11487460343449528,-0.2956592676299645,0.6984707313156334,0.002207377438801204,1.33596472752481
| 3,120
|
Intermediate filament protein, conserved site [IPR018039]
| 7
| 8
| 2.667395
| 0.007644
|
Q16352,P07197,P20700,P08670,P07196,Q03252,P02545
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
66,105,231,16,22,182,119
|
119,22,105,16,231,290,182,66
|
2.01246909431283,3.30934871430298,2.1238431973235943,3.570223146966479,1.4036332115706927,1.2676972286857384,1.6162802105485474,2.44886013744723
| 3,120
|
Intermediate filament, rod domain [IPR039008]
| 7
| 8
| 2.667395
| 0.007644
|
Q16352,P07197,P20700,P08670,P07196,Q03252,P02545
|
Sequence
|
InterPro Domain
|
interpro_domain
|
66,105,231,16,22,182,119
|
119,22,105,16,231,290,182,66
|
2.01246909431283,3.30934871430298,2.1238431973235943,3.570223146966479,1.4036332115706927,1.2676972286857384,1.6162802105485474,2.44886013744723
| 3,120
|
Oxidative phosphorylation
| 25
| 62
| 2.650669
| 0.008033
|
P00846,P24539,O75964,P22695,P14406,P00403,P25705,P06576,Q9Y6N1,O95168,O14949,O96000,O75947,Q93050,Q7KZN9,Q9Y487,Q9UDW1,P13073,O14548,O95169,Q9Y6M9,Q15904,P14927,P56385,P36543
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
7,523,15,401,19,276,533,156,303,555,58,65,570,79,465,88,93,98,479,609,632,244,249,126,373
|
3093,2410,479,58,2930,1336,2803,878,1758,738,570,15,555,609,1677,2204,65,276,7,2299,156,1569,1428,1711,98,19,249,1312,2182,684,1650,1887,717,401,523,533,2207,2381,2302,624,373,1432,1654,2105,3036,2304,2628,126,1683,3010,244,1147,1947,465,1053,79,2975,93,828,88,632,303
|
-2.243291875020247,-0.6414835578447224,0.8448142839802352,2.51931754717366,-1.2509707594161343,0.03457322912919779,-1.0232974504893133,0.38159146097785057,-0.2284164650375626,0.5038867309618552,0.6984707313156334,3.570223146966479,0.7132329833227257,0.6540102092830856,-0.17838548918434077,-0.5011773922472554,2.44886013744723,1.3087302728453603,3.813122404253874,-0.570991623394744,1.772033110463191,-0.11220249635179408,-0.030300711303461843,-0.1950246665788902,2.172842799903386,3.4042217306899554,1.3631033438829987,0.05070324943423878,-0.483828027884879,0.5642956462857995,-0.16178387178475653,-0.2956592676299645,0.534151825170032,1.0026016209135598,0.7719957292272027,0.7573477339359754,-0.5011773922472554,-0.623796233913705,-0.570991623394744,0.6391316883481546,1.0450737766397848,-0.030300711303461843,-0.16178387178475653,-0.4320264666261241,-1.5663663822078633,-0.570991623394744,-0.8207773259856875,1.974991705363492,-0.17838548918434077,-1.466283242033306,1.37663694769063,0.16264163820366534,-0.3295134311551762,0.8737472783538901,0.24157788767834681,2.353937773187976,-1.3676009439777808,2.233668543940409,0.44298832212023614,2.281995142154195,0.6391316883481546,1.226444230698108
| 3,120
|
Proton transmembrane transport
| 19
| 46
| 2.647853
| 0.0081
|
P00846,P24539,O75964,Q9UJZ1,P00403,P25705,P06576,Q8TAD4,Q13423,O75947,O43707,Q99653,Q7KZN9,Q9UDW1,P13073,O14548,Q99623,P56385,P36543
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
7,523,15,543,276,533,156,448,60,570,569,330,465,93,98,479,630,126,373
|
2410,479,1258,569,2803,570,15,276,7,2299,1544,2605,156,1569,1711,2256,98,684,1650,1887,523,533,2955,2302,624,373,1432,1654,2105,1768,2628,126,1683,2163,732,60,465,448,3083,630,330,1605,93,2653,828,543
|
-0.6414835578447224,0.8448142839802352,0.0828583342496927,0.6984707313156334,-1.0232974504893133,0.6984707313156334,3.570223146966479,1.3087302728453603,3.813122404253874,-0.570991623394744,-0.09574924303379817,-0.8026462174024811,1.772033110463191,-0.11220249635179408,-0.1950246665788902,-0.5360007060205642,2.172842799903386,0.5642956462857995,-0.16178387178475653,-0.2956592676299645,0.7719957292272027,0.7573477339359754,-1.3090459546983426,-0.570991623394744,0.6391316883481546,1.0450737766397848,-0.030300711303461843,-0.16178387178475653,-0.4320264666261241,-0.2284164650375626,-0.8207773259856875,1.974991705363492,-0.17838548918434077,-0.46651989752259204,0.5190345053695938,2.51931754717366,0.8737472783538901,0.902570585002106,-1.960285301094072,0.6391316883481546,1.1432677072413866,-0.12869256222156378,2.233668543940409,-0.8389541891155845,0.44298832212023614,0.7573477339359754
| 3,120
|
Electron transport chain oxphos system in mitochondria
| 22
| 54
| 2.555608
| 0.0106
|
P00846,P24539,O75964,P22695,P14406,P00403,P25705,P06576,Q9Y6N1,O95168,O14949,O96000,O75947,Q7KZN9,Q9UDW1,P13073,O14548,O95169,O75880,Q9Y6M9,P14927,P56385
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
7,523,15,401,19,276,533,156,303,555,58,65,570,465,93,98,479,609,608,632,249,126
|
3093,2410,479,58,2930,1336,2803,878,1758,738,608,570,15,555,609,1677,2204,65,276,7,2299,2605,156,1428,1711,2256,2657,98,19,249,1312,2182,684,717,401,523,533,2207,2381,2302,624,1654,2105,3036,2304,2628,126,1147,1947,465,93,762,632,303
|
-2.243291875020247,-0.6414835578447224,0.8448142839802352,2.51931754717366,-1.2509707594161343,0.03457322912919779,-1.0232974504893133,0.38159146097785057,-0.2284164650375626,0.5038867309618552,0.6540102092830856,0.6984707313156334,3.570223146966479,0.7132329833227257,0.6540102092830856,-0.17838548918434077,-0.5011773922472554,2.44886013744723,1.3087302728453603,3.813122404253874,-0.570991623394744,-0.8026462174024811,1.772033110463191,-0.030300711303461843,-0.1950246665788902,-0.5360007060205642,-0.8571770657812502,2.172842799903386,3.4042217306899554,1.3631033438829987,0.05070324943423878,-0.483828027884879,0.5642956462857995,0.534151825170032,1.0026016209135598,0.7719957292272027,0.7573477339359754,-0.5011773922472554,-0.623796233913705,-0.570991623394744,0.6391316883481546,-0.16178387178475653,-0.4320264666261241,-1.5663663822078633,-0.570991623394744,-0.8207773259856875,1.974991705363492,0.16264163820366534,-0.3295134311551762,0.8737472783538901,2.233668543940409,0.5038867309618552,0.6391316883481546,1.226444230698108
| 3,120
|
Ion transmembrane transporter activity
| 35
| 105
| 2.47032
| 0.013499
|
Q8TB61,P00846,P21796,P24539,O75964,Q00535,P00403,P06576,Q15043,P30825,O43772,P45880,Q70HW3,Q9HD20,Q9Y277,Q8TAD4,Q13423,P98194,P16615,Q6P4A7,Q9H2D1,Q9BQT8,Q93050,Q93034,Q7KZN9,Q9Y487,Q9UDW1,Q9UJS0,P13073,P41440,O14548,Q8N4V1,Q6P4Q7,P56385,P36543
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
517,7,8,523,15,154,276,156,417,35,39,45,46,55,319,448,60,446,444,456,76,467,79,335,465,88,93,490,98,482,479,120,380,126,373
|
2550,479,1258,665,39,2007,982,570,15,964,1961,276,7,1544,1077,2605,156,1064,1050,1182,1005,1569,2940,1711,2531,2256,2657,98,444,890,684,1650,1887,8,1184,523,533,35,2302,767,624,373,1432,482,45,1654,2105,1768,2769,743,868,2628,126,1683,2956,446,2163,154,990,732,60,1269,840,417,1468,1660,2214,1386,1949,456,380,1661,46,465,120,693,448,517,995,2545,335,79,1070,2909,467,2683,1583,1473,76,2221,1605,1673,2091,55,737,1097,761,93,828,490,959,319,88,3076,850
|
-0.7485248627310643,0.8448142839802352,0.0828583342496927,0.5793224179068317,2.8849739127891,-0.3805901708428884,0.2885413384136224,0.6984707313156334,3.570223146966479,0.30413037071405097,-0.34649940710130533,1.3087302728453603,3.813122404253874,-0.09574924303379817,0.21010374774524396,-0.8026462174024811,1.772033110463191,0.2258574389042269,0.24157788767834681,0.13083109947309807,0.27291968269656813,-0.11220249635179408,-1.2702763896857583,-0.1950246665788902,-0.7305742271780316,-0.5360007060205642,-0.8571770657812502,2.172842799903386,0.902570585002106,0.3661632883154021,0.5642956462857995,-0.16178387178475653,-0.2956592676299645,3.813122404253874,0.13083109947309807,0.7719957292272027,0.7573477339359754,3.0179282568081494,-0.570991623394744,0.48870836441780346,0.6391316883481546,1.0450737766397848,-0.030300711303461843,0.8448142839802352,2.7838025090073337,-0.16178387178475653,-0.4320264666261241,-0.2284164650375626,-0.967495404620523,0.5038867309618552,0.3969879056771085,-0.8207773259856875,1.974991705363492,-0.17838548918434077,-1.3090459546983426,0.902570585002106,-0.46651989752259204,1.7848732800962697,0.2885413384136224,0.5190345053695938,2.51931754717366,0.0828583342496927,0.42768619226574317,0.9598918250269893,-0.046608532900190375,-0.16178387178475653,-0.5011773922472554,0.002207377438801204,-0.3295134311551762,0.8881725845149391,1.0450737766397848,-0.16178387178475653,2.7724824566536013,0.8737472783538901,2.01246909431283,0.5642956462857995,0.902570585002106,0.786615468427979,0.2885413384136224,-0.7305742271780316,1.1293168573183845,2.353937773187976,0.2258574389042269,-1.1933666554371067,0.8737472783538901,-0.8754462172552409,-0.11220249635179408,-0.046608532900190375,2.3658651509983173,-0.5011773922472554,-0.12869256222156378,-0.16178387178475653,-0.41484073446716224,2.60074042050876,0.5190345053695938,0.21010374774524396,0.5038867309618552,2.233668543940409,0.44298832212023614,0.8448142839802352,0.3196869315450229,1.1849686248979059,2.281995142154195,-1.8334699706989743,0.42768619226574317
| 3,120
|
Mitochondrial membrane organization
| 17
| 44
| 2.434992
| 0.014892
|
Q5XKP0,P49840,Q9Y5J9,O95140,Q15070,Q3ZCQ8,O60313,Q9P0J0,P45880,Q9Y4W6,Q13505,Q9NS69,Q9NX63,O14737,Q53H12,Q16891,O75431
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
578,131,461,481,170,329,480,371,45,211,47,77,148,95,536,316,313
|
2463,95,480,313,1426,481,964,1732,2605,1588,1963,2256,2955,2281,2732,1988,2185,45,2532,131,702,1360,47,170,316,329,536,578,1273,1897,1247,594,2343,1981,77,810,148,371,762,2434,211,2225,461,2071
|
-0.6769882967991228,2.209394294309303,0.8448142839802352,1.1849686248979059,-0.030300711303461843,0.8448142839802352,0.30413037071405097,-0.21170159451326637,-0.8026462174024811,-0.12869256222156378,-0.34649940710130533,-0.5360007060205642,-1.3090459546983426,-0.5534751015591063,-0.9305339680832876,-0.3635249182132702,-0.483828027884879,2.7838025090073337,-0.7305742271780316,1.9373348286481238,0.5492388269345314,0.018407995915568375,2.7384264660489417,1.6815558467757523,1.1849686248979059,1.1432677072413866,0.7573477339359754,0.6984707313156334,0.0828583342496927,-0.2956592676299645,0.09888373702173922,0.6836796028570836,-0.5885504992892956,-0.34649940710130533,2.3658651509983173,0.4582592999615156,1.8232677727408004,1.0591788621121219,0.5038867309618552,-0.6414835578447224,1.5106857256113622,-0.5011773922472554,0.8881725845149391,-0.3976953730192357
| 3,120
|
mRNA splicing factor
| 18
| 58
| 2.421741
| 0.015446
|
Q13595,Q9BWF3,P98179,Q16629,P38159,O43719,Q15233,P35637,P23246,Q92804,Q07666,Q8WXF1,Q01844,Q13242,P62995,Q14011,Q07955,O75934
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
226,360,36,357,103,298,333,174,430,113,439,52,463,183,213,56,243,407
|
2097,832,298,1614,554,1615,407,2376,765,1006,1734,1183,854,430,800,174,103,1967,1108,2752,3008,213,1437,36,463,439,243,1521,2450,2662,491,183,590,859,226,56,1349,333,1323,2422,991,923,992,357,2788,924,1952,2168,805,52,113,722,997,360,1637,1931,2965,2621
|
-0.4320264666261241,0.42768619226574317,1.226444230698108,-0.14521962532452135,0.7132329833227257,-0.14521962532452135,0.9741550117257047,-0.623796233913705,0.48870836441780346,0.27291968269656813,-0.21170159451326637,0.13083109947309807,0.4123527679415628,0.931285129418382,0.4582592999615156,1.6424561771136268,2.136121609666896,-0.34649940710130533,0.1943166566085935,-0.9489908781534787,-1.466283242033306,1.497384815530289,-0.030300711303461843,3.0179282568081494,0.8737472783538901,0.9169413951198621,1.37663694769063,-0.07933261901370642,-0.6592141662818555,-0.8571770657812502,0.8303063613261049,1.6162802105485474,0.6836796028570836,0.4123527679415628,1.4170960559577421,2.554314581480143,0.03457322912919779,1.1293168573183845,0.05070324943423878,-0.6414835578447224,0.2885413384136224,0.35070324111746226,0.2885413384136224,1.0732579772137116,-0.9860478230479183,0.35070324111746226,-0.3295134311551762,-0.46651989752259204,0.4582592999615156,2.6583969279832234,2.062163025553647,0.534151825170032,0.2885413384136224,1.0732579772137116,-0.14521962532452135,-0.312566785682029,-1.328510537079896,-0.8026462174024811
| 3,120
|
Protein serine kinase activity
| 20
| 58
| 2.421437
| 0.015459
|
P06493,P49840,Q99640,O75116,Q00536,Q9P289,P50750,Q00535,P24941,P27361,P54646,P51812,Q13464,O75962,P31751,Q7KZI7,Q13555,Q13557,Q16513,Q15418
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
129,131,654,521,18,542,151,154,31,551,423,172,189,203,206,472,356,493,626,127
|
815,2795,816,2348,1205,521,203,1823,2047,1883,129,983,1287,1916,2135,31,551,1407,206,1796,2353,1766,2054,1738,131,702,2907,151,172,2284,423,2559,154,18,2645,1864,1218,1361,189,2082,969,356,493,784,127,626,1552,472,2473,652,2248,654,2802,1224,1672,1160,542,1020
|
0.44298832212023614,-1.0046484114833856,0.44298832212023614,-0.606151958922442,0.11487460343449528,0.7719957292272027,1.523963856715977,-0.2619608096795884,-0.3976953730192357,-0.2956592676299645,1.9499071826655876,0.2885413384136224,0.06679822788517814,-0.312566785682029,-0.44925278266923796,3.105368151447201,0.7279664846318218,-0.014028799969153467,1.5106857256113622,-0.24516947172325332,-0.606151958922442,-0.2284164650375626,-0.3976953730192357,-0.21170159451326637,1.9373348286481238,0.5492388269345314,-1.1933666554371067,1.7976923957350528,1.6555112222855055,-0.5534751015591063,0.9456019017002357,-0.7485248627310643,1.7848732800962697,3.4460375576629554,-0.8389541891155845,-0.2787906755702021,0.11487460343449528,0.018407995915568375,1.5900158562501612,-0.41484073446716224,0.30413037071405097,1.0732579772137116,0.8303063613261049,0.47349926724163727,1.9624594510337707,0.6391316883481546,-0.09574924303379817,0.8592945504534439,-0.6769882967991228,0.6092863520442148,-0.5185682109135206,0.6092863520442148,-1.0046484114833856,0.11487460343449528,-0.16178387178475653,0.16264163820366534,0.7573477339359754,0.27291968269656813
| 3,120
|
Serine/threonine-protein kinase
| 20
| 58
| 2.421437
| 0.015459
|
P06493,P49840,Q99640,O75116,Q00536,Q9P289,P50750,Q00535,P24941,P27361,P54646,P51812,Q13464,O75962,P31751,Q7KZI7,Q13555,Q13557,Q16513,Q15418
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
129,131,654,521,18,542,151,154,31,551,423,172,189,203,206,472,356,493,626,127
|
815,2795,816,2348,1205,521,203,1823,2047,1883,129,983,1287,1916,2135,31,551,1407,206,1796,2353,1766,2054,1738,131,702,2907,151,172,2284,423,2559,154,18,2645,1864,1218,1361,189,2082,969,356,493,784,127,626,1552,472,2473,652,2248,654,2802,1224,1672,1160,542,1020
|
0.44298832212023614,-1.0046484114833856,0.44298832212023614,-0.606151958922442,0.11487460343449528,0.7719957292272027,1.523963856715977,-0.2619608096795884,-0.3976953730192357,-0.2956592676299645,1.9499071826655876,0.2885413384136224,0.06679822788517814,-0.312566785682029,-0.44925278266923796,3.105368151447201,0.7279664846318218,-0.014028799969153467,1.5106857256113622,-0.24516947172325332,-0.606151958922442,-0.2284164650375626,-0.3976953730192357,-0.21170159451326637,1.9373348286481238,0.5492388269345314,-1.1933666554371067,1.7976923957350528,1.6555112222855055,-0.5534751015591063,0.9456019017002357,-0.7485248627310643,1.7848732800962697,3.4460375576629554,-0.8389541891155845,-0.2787906755702021,0.11487460343449528,0.018407995915568375,1.5900158562501612,-0.41484073446716224,0.30413037071405097,1.0732579772137116,0.8303063613261049,0.47349926724163727,1.9624594510337707,0.6391316883481546,-0.09574924303379817,0.8592945504534439,-0.6769882967991228,0.6092863520442148,-0.5185682109135206,0.6092863520442148,-1.0046484114833856,0.11487460343449528,-0.16178387178475653,0.16264163820366534,0.7573477339359754,0.27291968269656813
| 3,120
|
Abnormal femoral neck head morphology
| 14
| 45
| 2.383131
| 0.017166
|
P02545,Q7LGA3,Q96HY6,O75718,P51812,Q96AY3,Q6NUQ1,Q7RTS9,O95831,Q96L58,Q9Y487,P16278,Q96A33,O75431
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
119,4,381,241,172,271,379,87,24,348,88,315,347,313
|
2671,933,2622,313,2202,241,405,24,119,797,315,2674,2927,1407,1988,2880,1265,172,868,2020,732,2389,2211,2166,2028,379,2896,4,87,2472,347,271,381,348,653,2861,755,489,2498,1753,1816,1019,1607,88,1334
|
-0.8754462172552409,0.3352111717576097,-0.8207773259856875,1.1849686248979059,-0.5011773922472554,1.37663694769063,0.988391573395426,3.2454831822206605,2.01246909431283,0.4582592999615156,1.1849686248979059,-0.8754462172552409,-1.231717470627754,-0.014028799969153467,-0.3635249182132702,-1.1552214493474031,0.0828583342496927,1.6555112222855055,0.3969879056771085,-0.3805901708428884,0.5190345053695938,-0.623796233913705,-0.5011773922472554,-0.46651989752259204,-0.3805901708428884,1.0450737766397848,-1.1742685053617696,3.8925314743339694,2.281995142154195,-0.6769882967991228,1.101338722336577,1.322359527263043,1.0450737766397848,1.101338722336577,0.6092863520442148,-1.1172794037264824,0.5038867309618552,0.8448142839802352,-0.6948061890014895,-0.21170159451326637,-0.24516947172325332,0.27291968269656813,-0.12869256222156378,2.281995142154195,0.05070324943423878
| 3,120
|
Calcium-binding protein
| 9
| 20
| 2.37404
| 0.017595
|
P80303,Q9BPX6,P43307,O43852,Q14257,Q8IYU8,Q9BRK5,Q99584,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
3,67,6,70,9,145,246,252,30
|
70,2104,2838,2509,6,1242,2306,3,30,9,265,1975,1839,145,845,1447,252,67,246,1541
|
2.41339669379397,-0.4320264666261241,-1.079538114927136,-0.7126680845484551,3.84298985043204,0.09888373702173922,-0.570991623394744,3.912265751114164,3.1270818699928937,3.793150878054305,1.33596472752481,-0.34649940710130533,-0.2619608096795884,1.8360241868746086,0.42768619226574317,-0.030300711303461843,1.3631033438829987,2.44886013744723,1.37663694769063,-0.07933261901370642
| 3,120
|
calmodulin-related
| 8
| 14
| 2.345523
| 0.019
|
P80303,Q9BPX6,O43852,Q14257,Q8IYU8,Q9BRK5,Q99584,Q02818
|
Functions
|
Panther Protein class
|
panther_protein_class
|
3,67,70,9,145,246,252,30
|
70,1620,2838,2509,2306,3,30,9,265,145,1447,252,67,246
|
2.41339669379397,-0.14521962532452135,-1.079538114927136,-0.7126680845484551,-0.570991623394744,3.912265751114164,3.1270818699928937,3.793150878054305,1.33596472752481,1.8360241868746086,-0.030300711303461843,1.3631033438829987,2.44886013744723,1.37663694769063
| 3,120
|
Proton transmembrane transporter activity
| 16
| 35
| 2.344927
| 0.019031
|
P13073,O75947,P00846,O14548,Q13423,P24539,O75964,Q93050,Q9UDW1,Q7KZN9,Q9Y487,P00403,P25705,P06576,P56385,P36543
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
98,570,7,479,60,523,15,79,93,465,88,276,533,156,126,373
|
479,570,15,964,276,7,2605,156,1569,1711,2256,98,684,1650,1887,523,533,2302,624,373,1432,1654,2105,1768,2628,126,1683,2163,60,465,79,1605,93,828,88
|
0.8448142839802352,0.6984707313156334,3.570223146966479,0.30413037071405097,1.3087302728453603,3.813122404253874,-0.8026462174024811,1.772033110463191,-0.11220249635179408,-0.1950246665788902,-0.5360007060205642,2.172842799903386,0.5642956462857995,-0.16178387178475653,-0.2956592676299645,0.7719957292272027,0.7573477339359754,-0.570991623394744,0.6391316883481546,1.0450737766397848,-0.030300711303461843,-0.16178387178475653,-0.4320264666261241,-0.2284164650375626,-0.8207773259856875,1.974991705363492,-0.17838548918434077,-0.46651989752259204,2.51931754717366,0.8737472783538901,2.353937773187976,-0.12869256222156378,2.233668543940409,0.44298832212023614,2.281995142154195
| 3,120
|
Regulation of mrna splicing via spliceosome
| 18
| 62
| 2.326778
| 0.019977
|
Q9Y580,Q9UHX1,Q9Y2W1,P61978,P98179,P22626,Q13595,Q9BWF3,Q16629,P38159,Q07021,Q15007,Q07666,P62995,P52756,Q13242,Q14011,P98175
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
288,388,549,255,36,193,226,360,357,103,233,494,439,213,406,183,56,376
|
1456,554,1062,1006,1008,914,2442,2014,2102,854,193,1104,1795,2914,1517,103,1345,667,625,406,1216,255,213,1437,376,36,2724,233,439,1521,2450,2662,183,859,839,226,56,1524,494,1323,733,992,357,1719,2964,2168,1579,1691,1692,1366,927,997,2248,1416,1303,360,1905,388,1983,549,288,1334
|
-0.046608532900190375,0.7132329833227257,0.2258574389042269,0.27291968269656813,0.27291968269656813,0.35070324111746226,-0.6592141662818555,-0.3805901708428884,-0.4320264666261241,0.4123527679415628,1.5768503245839907,0.1943166566085935,-0.24516947172325332,-1.2125162070669009,-0.07933261901370642,2.136121609666896,0.03457322912919779,0.5793224179068317,0.6391316883481546,0.988391573395426,0.11487460343449528,1.3495459683507376,1.497384815530289,-0.030300711303461843,1.0450737766397848,3.0179282568081494,-0.9121244013006663,1.4036332115706927,0.9169413951198621,-0.07933261901370642,-0.6592141662818555,-0.8571770657812502,1.6162802105485474,0.4123527679415628,0.42768619226574317,1.4170960559577421,2.554314581480143,-0.07933261901370642,0.8303063613261049,0.05070324943423878,0.5190345053695938,0.2885413384136224,1.0732579772137116,-0.1950246665788902,-1.328510537079896,-0.46651989752259204,-0.11220249635179408,-0.17838548918434077,-0.17838548918434077,0.018407995915568375,0.35070324111746226,0.2885413384136224,-0.5185682109135206,-0.014028799969153467,0.06679822788517814,1.0732579772137116,-0.2956592676299645,1.0309426134342197,-0.34649940710130533,0.7426713601480582,1.2813992197433883,0.05070324943423878
| 3,120
|
Abnormal muscle fiber morphology
| 16
| 71
| 2.325421
| 0.020049
|
P22626,P61978,Q9BPX6,Q99720,P00846,O14979,Q9H2D1,Q70HW3,P35637,Q9Y4W6,P50402,P07196,O95831,P02545,P06753,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
193,255,67,102,7,133,76,46,174,211,212,22,24,119,220,159
|
2410,1121,133,2179,480,888,715,24,912,276,7,119,2299,3101,220,22,2012,1008,2256,586,2857,193,159,2381,1517,174,2282,500,1241,212,1187,667,2769,2469,1085,2018,255,1626,2081,552,2243,2359,2308,2489,689,2597,802,46,651,385,1389,1840,457,1092,825,2801,1809,102,67,427,1810,901,2172,76,1000,1228,1231,2434,2318,211,2436
|
-0.6414835578447224,0.17849600673831648,1.9247423169719036,-0.483828027884879,0.8448142839802352,0.3661632883154021,0.534151825170032,3.2454831822206605,0.35070324111746226,1.3087302728453603,3.813122404253874,2.01246909431283,-0.570991623394744,-2.310287019843537,1.443951626246411,3.30934871430298,-0.3805901708428884,0.27291968269656813,-0.5360007060205642,0.6836796028570836,-1.1172794037264824,1.5768503245839907,1.7591718093586464,-0.623796233913705,-0.07933261901370642,1.6424561771136268,-0.5534751015591063,0.8157706641011584,0.09888373702173922,1.497384815530289,0.13083109947309807,0.5793224179068317,-0.967495404620523,-0.6769882967991228,0.21010374774524396,-0.3805901708428884,1.3495459683507376,-0.14521962532452135,-0.41484073446716224,0.7279664846318218,-0.5185682109135206,-0.606151958922442,-0.570991623394744,-0.6948061890014895,0.5642956462857995,-0.7845606066334213,0.4582592999615156,2.7724824566536013,0.6092863520442148,1.0309426134342197,0.002207377438801204,-0.2619608096795884,0.8881725845149391,0.21010374774524396,0.44298832212023614,-1.0046484114833856,-0.24516947172325332,2.1483809702874805,2.44886013744723,0.9456019017002357,-0.24516947172325332,0.3661632883154021,-0.46651989752259204,2.3658651509983173,0.2885413384136224,0.11487460343449528,0.11487460343449528,-0.6414835578447224,-0.570991623394744,1.5106857256113622,-0.6414835578447224
| 3,120
|
Metallopeptidase activity
| 19
| 41
| 2.320331
| 0.020323
|
Q96TA2,Q969V3,O15372,P22695,Q9NQH7,O75844,Q5JRX3,P36551,O00303,P55786,O75976,Q9NZ08,Q9UIQ6,Q9BYT8,Q96E52,Q9Y4W6,O43847,P42892,Q10713
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
527,660,520,401,539,405,410,409,664,42,429,176,50,708,594,211,342,106,238
|
664,1564,520,342,1648,405,429,700,819,1857,2322,1618,401,2576,409,106,2186,1189,1127,42,238,410,2788,1663,1530,1667,660,594,1496,527,1449,998,708,2988,1002,539,1699,905,176,50,211
|
0.5793224179068317,-0.11220249635179408,0.7719957292272027,1.101338722336577,-0.16178387178475653,0.988391573395426,0.931285129418382,0.5492388269345314,0.44298832212023614,-0.2787906755702021,-0.5885504992892956,-0.14521962532452135,1.0026016209135598,-0.766520239175899,0.9741550117257047,2.1238431973235943,-0.483828027884879,0.13083109947309807,0.17849600673831648,2.851390894707872,1.3901468727742385,0.9741550117257047,-0.9860478230479183,-0.16178387178475653,-0.07933261901370642,-0.16178387178475653,0.594319275549686,0.6836796028570836,-0.06295244245028012,0.7719957292272027,-0.030300711303461843,0.2885413384136224,0.5492388269345314,-1.4069085672183435,0.2885413384136224,0.7573477339359754,-0.17838548918434077,0.3661632883154021,1.6424561771136268,2.692792974087149,1.5106857256113622
| 3,120
|
Impaired proprioception
| 14
| 38
| 2.312147
| 0.02077
|
O14773,O43819,O95140,P00846,P41440,P20700,Q9H6K4,O75298,Q9NR77,P07196,P54802,Q8IV08,Q13217,Q15120
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,514,481,7,482,231,121,188,85,22,242,89,157,511
|
908,160,2527,1280,514,188,729,481,7,2234,22,1545,1572,2257,231,2851,2282,482,1085,242,1433,2018,2723,1626,157,511,2215,89,537,1840,1170,2801,1809,1223,121,85,1332,1478
|
0.35070324111746226,1.7462892988618541,-0.7305742271780316,0.06679822788517814,0.786615468427979,1.5900158562501612,0.5190345053695938,0.8448142839802352,3.813122404253874,-0.5185682109135206,3.30934871430298,-0.09574924303379817,-0.11220249635179408,-0.5360007060205642,1.4036332115706927,-1.0983838132255241,-0.5534751015591063,0.8448142839802352,0.21010374774524396,1.37663694769063,-0.030300711303461843,-0.3805901708428884,-0.9121244013006663,-0.14521962532452135,1.772033110463191,0.8012070731266786,-0.5011773922472554,2.2699410728253326,0.7573477339359754,-0.2619608096795884,0.14675338988725495,-1.0046484114833856,-0.24516947172325332,0.11487460343449528,2.01246909431283,2.306048494162799,0.05070324943423878,-0.046608532900190375
| 3,120
|
Protein kinase domain [IPR000719]
| 22
| 59
| 2.281935
| 0.022493
|
P06493,P49840,Q99640,Q96KB5,O75116,Q00536,Q9P289,P50750,Q00535,P24941,Q15375,P27361,P54646,P51812,Q13464,O75962,P31751,Q7KZI7,Q13555,Q13557,Q16513,Q15418
|
Sequence
|
InterPro Domain
|
interpro_domain
|
129,131,654,652,521,18,542,151,154,31,671,551,423,172,189,203,206,472,356,493,626,127
|
815,2795,816,2348,521,203,1823,2047,1883,129,983,1287,1916,2135,31,551,1407,206,1796,2353,1547,2054,1738,131,702,2907,151,172,2284,423,154,18,2645,1864,1218,1361,1550,189,2082,969,356,493,784,671,127,626,1552,2886,472,1928,2473,652,2248,654,2802,1672,1160,542,2174
|
0.44298832212023614,-1.0046484114833856,0.44298832212023614,-0.606151958922442,0.7719957292272027,1.523963856715977,-0.2619608096795884,-0.3976953730192357,-0.2956592676299645,1.9499071826655876,0.2885413384136224,0.06679822788517814,-0.312566785682029,-0.44925278266923796,3.105368151447201,0.7279664846318218,-0.014028799969153467,1.5106857256113622,-0.24516947172325332,-0.606151958922442,-0.09574924303379817,-0.3976953730192357,-0.21170159451326637,1.9373348286481238,0.5492388269345314,-1.1933666554371067,1.7976923957350528,1.6555112222855055,-0.5534751015591063,0.9456019017002357,1.7848732800962697,3.4460375576629554,-0.8389541891155845,-0.2787906755702021,0.11487460343449528,0.018407995915568375,-0.09574924303379817,1.5900158562501612,-0.41484073446716224,0.30413037071405097,1.0732579772137116,0.8303063613261049,0.47349926724163727,0.5793224179068317,1.9624594510337707,0.6391316883481546,-0.09574924303379817,-1.1552214493474031,0.8592945504534439,-0.312566785682029,-0.6769882967991228,0.6092863520442148,-0.5185682109135206,0.6092863520442148,-1.0046484114833856,-0.16178387178475653,0.16264163820366534,0.7573477339359754,-0.46651989752259204
| 3,120
|
Abnormal circulating lipid concentration
| 27
| 74
| 2.278914
| 0.022672
|
P22830,O75844,Q96MF7,P23786,P37268,O43772,Q15392,P57740,P28070,Q03252,Q15056,P40855,Q92734,O75431,O95470,O43707,P31751,P50402,O75381,Q4G0N4,Q9UJS0,Q9H9E3,P09622,O75880,Q15800,Q15904,P02545
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
12,405,26,159,166,39,296,304,51,182,576,437,580,313,321,569,206,212,219,599,490,489,610,608,495,244,119
|
2527,569,2098,39,1511,219,313,715,405,1238,608,321,119,1285,1825,610,2903,12,159,51,1212,206,1797,2659,1431,166,2825,437,2383,2354,1082,1164,1593,212,1682,2734,1126,2534,2644,304,3015,1833,2141,182,1595,745,837,2243,2389,576,296,1926,495,244,640,599,2775,1840,825,580,1248,26,1810,1997,1371,489,904,1401,1907,2781,490,1506,1279,2436
|
-0.7305742271780316,0.6984707313156334,-0.4320264666261241,2.8849739127891,-0.07933261901370642,1.4573445331488604,1.1849686248979059,0.534151825170032,0.988391573395426,0.09888373702173922,0.6540102092830856,1.1710934886626958,2.01246909431283,0.06679822788517814,-0.2619608096795884,0.6540102092830856,-1.1933666554371067,3.682438533398048,1.7591718093586464,2.681343990663541,0.11487460343449528,1.5106857256113622,-0.24516947172325332,-0.8571770657812502,-0.030300711303461843,1.6945455888156644,-1.0419952231737202,0.9169413951198621,-0.623796233913705,-0.606151958922442,0.21010374774524396,0.14675338988725495,-0.12869256222156378,1.497384815530289,-0.17838548918434077,-0.9305339680832876,0.17849600673831648,-0.7305742271780316,-0.8389541891155845,1.2126438954569019,-1.486186386406625,-0.2619608096795884,-0.44925278266923796,1.6162802105485474,-0.12869256222156378,0.5038867309618552,0.42768619226574317,-0.5185682109135206,-0.623796233913705,0.6984707313156334,1.2402198321498792,-0.312566785682029,0.8303063613261049,1.37663694769063,0.6242237793066672,0.6688594713374666,-0.967495404620523,-0.2619608096795884,0.44298832212023614,0.6984707313156334,0.09888373702173922,3.1811140194189464,-0.24516947172325332,-0.3635249182132702,0.018407995915568375,0.8448142839802352,0.3661632883154021,0.002207377438801204,-0.2956592676299645,-0.967495404620523,0.8448142839802352,-0.06295244245028012,0.0828583342496927,-0.6414835578447224
| 3,120
|
Positive regulation of intracellular protein transport
| 13
| 54
| 2.263938
| 0.023578
|
O00459,P06493,P49840,Q9Y282,Q99653,P55786,O43464,P31751,P50402,Q9C0E2,Q00535,Q15154,O14737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
222,129,131,165,330,42,389,206,212,216,154,286,95
|
2951,1203,222,95,1510,389,2073,1122,1938,2279,129,821,400,2696,1287,2135,2674,2281,206,131,702,212,917,42,2995,1319,2630,2057,154,1864,1773,1409,1774,286,1552,1896,2426,1090,1899,940,1250,330,1156,216,604,1422,513,2249,862,2669,2653,165,1910,1455
|
-1.3090459546983426,0.11487460343449528,1.4305354972585869,2.209394294309303,-0.07933261901370642,1.0167852644421618,-0.41484073446716224,0.17849600673831648,-0.3295134311551762,-0.5534751015591063,1.9499071826655876,0.44298832212023614,1.0026016209135598,-0.8937619071209996,0.06679822788517814,-0.44925278266923796,-0.8754462172552409,-0.5534751015591063,1.5106857256113622,1.9373348286481238,0.5492388269345314,1.497384815530289,0.35070324111746226,2.851390894707872,-1.426644682165865,0.05070324943423878,-0.8207773259856875,-0.3976953730192357,1.7848732800962697,-0.2787906755702021,-0.2284164650375626,-0.014028799969153467,-0.2284164650375626,1.2813992197433883,-0.09574924303379817,-0.2956592676299645,-0.6414835578447224,0.21010374774524396,-0.2956592676299645,0.3352111717576097,0.09888373702173922,1.1432677072413866,0.16264163820366534,1.497384815530289,0.6688594713374666,-0.014028799969153467,0.8012070731266786,-0.5185682109135206,0.4123527679415628,-0.8571770657812502,-0.8389541891155845,1.72046033576955,-0.2956592676299645,-0.030300711303461843
| 3,120
|
Abnormality of salivation
| 16
| 47
| 2.250485
| 0.024418
|
Q9UHD9,Q13501,P55795,P51812,Q15233,P35637,Q9BVA1,P01889,Q92804,Q9NR77,Q8N0X7,Q03252,Q9UQN3,P43243,Q15165,P34897
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
192,552,232,172,333,174,564,557,113,85,537,182,582,500,27,285
|
2527,1881,2573,1791,557,2993,1792,1008,2506,766,1429,285,174,767,1125,500,1290,1830,1966,2797,172,868,2018,232,2809,639,182,1627,1409,552,575,2389,27,333,537,1994,113,2634,2801,2456,1223,564,2151,1397,85,192,582
|
-0.7305742271780316,-0.2956592676299645,-0.766520239175899,-0.24516947172325332,0.7132329833227257,-1.426644682165865,-0.24516947172325332,0.27291968269656813,-0.7126680845484551,0.48870836441780346,-0.030300711303461843,1.2813992197433883,1.6424561771136268,0.48870836441780346,0.17849600673831648,0.8157706641011584,0.06679822788517814,-0.2619608096795884,-0.34649940710130533,-1.0046484114833856,1.6555112222855055,0.3969879056771085,-0.3805901708428884,1.4036332115706927,-1.0232974504893133,0.6242237793066672,1.6162802105485474,-0.14521962532452135,-0.014028799969153467,0.7279664846318218,0.6984707313156334,-0.623796233913705,3.1703362354359217,1.1293168573183845,0.7573477339359754,-0.3635249182132702,2.062163025553647,-0.8207773259856875,-1.0046484114833856,-0.6592141662818555,0.11487460343449528,0.7132329833227257,-0.44925278266923796,0.002207377438801204,2.306048494162799,1.5900158562501612,0.6984707313156334
| 3,120
|
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
| 24
| 66
| 2.245031
| 0.024766
|
O43819,P00846,P24539,O75964,P22695,P00403,P25705,P06576,Q9Y6N1,O95168,O14949,O96000,O75947,Q9BQ95,Q7L592,Q9UDW1,P13073,O14548,O95169,O75880,Q9P0J0,Q9Y6M9,P14927,P56385
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
514,7,523,15,401,276,533,156,303,555,58,65,570,459,346,93,98,479,609,608,371,632,249,126
|
3093,2410,479,58,2930,514,1336,2803,878,1758,738,608,570,15,555,609,1677,2204,65,276,7,2299,156,1569,1428,1711,98,2156,249,1312,2182,684,717,401,523,533,2207,2381,2302,624,2415,1622,1654,2105,3036,2304,2628,126,1034,1133,1147,1947,346,1053,1245,2860,459,1393,1371,1017,1357,1043,371,93,632,303
|
-2.243291875020247,-0.6414835578447224,0.8448142839802352,2.51931754717366,-1.2509707594161343,0.786615468427979,0.03457322912919779,-1.0232974504893133,0.38159146097785057,-0.2284164650375626,0.5038867309618552,0.6540102092830856,0.6984707313156334,3.570223146966479,0.7132329833227257,0.6540102092830856,-0.17838548918434077,-0.5011773922472554,2.44886013744723,1.3087302728453603,3.813122404253874,-0.570991623394744,1.772033110463191,-0.11220249635179408,-0.030300711303461843,-0.1950246665788902,2.172842799903386,-0.46651989752259204,1.3631033438829987,0.05070324943423878,-0.483828027884879,0.5642956462857995,0.534151825170032,1.0026016209135598,0.7719957292272027,0.7573477339359754,-0.5011773922472554,-0.623796233913705,-0.570991623394744,0.6391316883481546,-0.6414835578447224,-0.14521962532452135,-0.16178387178475653,-0.4320264666261241,-1.5663663822078633,-0.570991623394744,-0.8207773259856875,1.974991705363492,0.2572652505088006,0.17849600673831648,0.16264163820366534,-0.3295134311551762,1.101338722336577,0.24157788767834681,0.09888373702173922,-1.1172794037264824,0.8881725845149391,0.002207377438801204,0.018407995915568375,0.27291968269656813,0.03457322912919779,0.2572652505088006,1.0591788621121219,2.233668543940409,0.6391316883481546,1.226444230698108
| 3,120
|
Abnormal peripheral nervous system physiology
| 17
| 48
| 2.230052
| 0.025744
|
P02545,O43681,O95140,Q7Z406,Q99720,O60313,Q9GZY8,Q9NQZ5,P20700,O95721,Q9NR77,P07196,O95831,Q9UBB4,P43243,Q92734,Q15120
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
119,665,481,651,102,480,604,204,231,81,85,22,24,477,500,580,511
|
681,764,2153,665,2179,480,481,81,24,119,1026,22,2257,2379,231,2302,2282,500,1082,2240,1187,1767,1126,1085,2018,3067,2809,2723,1865,1684,2308,511,651,2544,1444,1092,580,2801,102,604,204,85,2094,1401,1452,477,930,1478
|
0.5642956462857995,0.48870836441780346,-0.46651989752259204,0.5793224179068317,-0.483828027884879,0.8448142839802352,0.8448142839802352,2.34199247904662,3.2454831822206605,2.01246909431283,0.2572652505088006,3.30934871430298,-0.5360007060205642,-0.623796233913705,1.4036332115706927,-0.570991623394744,-0.5534751015591063,0.8157706641011584,0.21010374774524396,-0.5185682109135206,0.13083109947309807,-0.2284164650375626,0.17849600673831648,0.21010374774524396,-0.3805901708428884,-1.7709185436163724,-1.0232974504893133,-0.9121244013006663,-0.2787906755702021,-0.17838548918434077,-0.570991623394744,0.8012070731266786,0.6092863520442148,-0.7305742271780316,-0.030300711303461843,0.21010374774524396,0.6984707313156334,-1.0046484114833856,2.1483809702874805,0.6688594713374666,1.523963856715977,2.306048494162799,-0.41484073446716224,0.002207377438801204,-0.030300711303461843,0.8592945504534439,0.35070324111746226,-0.046608532900190375
| 3,120
|
Calmodulin
| 8
| 16
| 2.228703
| 0.025834
|
P80303,Q9BPX6,O43852,Q14257,Q8IYU8,Q9BRK5,Q99584,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
3,67,70,9,145,246,252,30
|
70,2838,2509,1242,2306,3,30,9,265,1975,1839,145,845,252,67,246
|
2.41339669379397,-1.079538114927136,-0.7126680845484551,0.09888373702173922,-0.570991623394744,3.912265751114164,3.1270818699928937,3.793150878054305,1.33596472752481,-0.34649940710130533,-0.2619608096795884,1.8360241868746086,0.42768619226574317,1.3631033438829987,2.44886013744723,1.37663694769063
| 3,120
|
Intracellular calcium-sensing protein
| 8
| 16
| 2.228703
| 0.025834
|
P80303,Q9BPX6,O43852,Q14257,Q8IYU8,Q9BRK5,Q99584,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
3,67,70,9,145,246,252,30
|
70,2838,2509,1242,2306,3,30,9,265,1975,1839,145,845,252,67,246
|
2.41339669379397,-1.079538114927136,-0.7126680845484551,0.09888373702173922,-0.570991623394744,3.912265751114164,3.1270818699928937,3.793150878054305,1.33596472752481,-0.34649940710130533,-0.2619608096795884,1.8360241868746086,0.42768619226574317,1.3631033438829987,2.44886013744723,1.37663694769063
| 3,120
|
transporter
| 23
| 55
| 2.223508
| 0.026182
|
Q567V2,O60830,Q9UJZ1,Q99567,O43681,P52292,O43772,Q15070,Q92973,O00629,P57740,Q7Z3B4,P55735,Q9HD45,Q8N1F7,Q9H2D1,Q9NR77,O43615,Q9C0E2,P41440,Q99805,P37198,Q8NFH4
|
Functions
|
Panther Protein class
|
panther_protein_class
|
2,14,543,538,665,668,39,170,695,422,304,308,438,311,190,76,85,584,216,482,382,499,642
|
1203,2501,422,2991,2924,1789,584,665,39,14,1338,2132,685,499,482,2260,2417,668,1831,1216,2769,743,2418,1548,438,304,2956,951,1685,170,2,2214,1661,308,190,642,1391,1275,1899,695,1556,1695,538,382,2909,2496,216,76,2685,311,85,3052,2792,543,2436
|
0.11487460343449528,-0.7126680845484551,0.9456019017002357,-1.426644682165865,-1.231717470627754,-0.24516947172325332,0.6836796028570836,0.5793224179068317,2.8849739127891,3.662148863096418,0.03457322912919779,-0.44925278266923796,0.5642956462857995,0.8157706641011584,0.8448142839802352,-0.5360007060205642,-0.6414835578447224,0.5793224179068317,-0.2619608096795884,0.11487460343449528,-0.967495404620523,0.5038867309618552,-0.6414835578447224,-0.09574924303379817,0.9169413951198621,1.2126438954569019,-1.3090459546983426,0.3196869315450229,-0.17838548918434077,1.6815558467757523,4.039411233472632,-0.5011773922472554,-0.16178387178475653,1.198818726904989,1.5900158562501612,0.6242237793066672,0.002207377438801204,0.0828583342496927,-0.2956592676299645,0.5642956462857995,-0.09574924303379817,-0.17838548918434077,0.7573477339359754,1.0450737766397848,-1.1933666554371067,-0.6948061890014895,1.497384815530289,2.3658651509983173,-0.8754462172552409,1.198818726904989,2.306048494162799,-1.6678956251559238,-0.9860478230479183,0.7573477339359754,-0.6414835578447224
| 3,120
|
Mitochondrial protein import
| 17
| 34
| 2.220857
| 0.026361
|
Q9UJS0,Q9Y5J9,P21796,Q3ZCQ8,Q15388,Q9NS69,O60830,Q13505,Q10713,Q9NX63,O14925,O43615,Q5JRX3,Q8N4H5,P25705,P06576,O75431
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
490,461,8,329,485,77,14,47,238,148,149,584,410,90,533,156,313
|
149,584,14,2796,313,1648,982,1426,609,912,156,1569,1545,2256,2657,8,533,1988,238,47,485,329,410,90,1842,2842,1229,77,148,490,2434,2225,461,2071
|
1.8104905344165125,0.6836796028570836,3.662148863096418,-1.0046484114833856,1.1849686248979059,-0.16178387178475653,0.2885413384136224,-0.030300711303461843,0.6540102092830856,0.35070324111746226,1.772033110463191,-0.11220249635179408,-0.09574924303379817,-0.5360007060205642,-0.8571770657812502,3.813122404253874,0.7573477339359754,-0.3635249182132702,1.3901468727742385,2.7384264660489417,0.8448142839802352,1.1432677072413866,0.9741550117257047,2.2699410728253326,-0.2619608096795884,-1.079538114927136,0.11487460343449528,2.3658651509983173,1.8232677727408004,0.8448142839802352,-0.6414835578447224,-0.5011773922472554,0.8881725845149391,-0.3976953730192357
| 3,120
|
Bowing of the legs
| 11
| 49
| 2.219906
| 0.026425
|
Q7LGA3,Q9NX62,Q32P28,Q13126,P08236,Q9NR77,Q7RTS9,Q96L58,O75718,P16278,O75431
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,168,139,112,205,85,87,348,241,315,313
|
2319,2098,1122,2622,313,241,2253,205,2322,315,454,1287,2674,2575,2927,1797,2353,1344,1291,1833,639,2141,2645,732,1595,112,2211,576,1597,139,4,87,2472,537,1365,2473,381,348,2337,1697,85,1056,1753,168,2781,1816,2318,1279,1334
|
-0.5885504992892956,-0.4320264666261241,0.17849600673831648,-0.8207773259856875,1.1849686248979059,1.37663694769063,-0.5360007060205642,1.5106857256113622,-0.5885504992892956,1.1849686248979059,0.8881725845149391,0.06679822788517814,-0.8754462172552409,-0.766520239175899,-1.231717470627754,-0.24516947172325332,-0.606151958922442,0.03457322912919779,0.06679822788517814,-0.2619608096795884,0.6242237793066672,-0.44925278266923796,-0.8389541891155845,0.5190345053695938,-0.12869256222156378,2.074537698699783,-0.5011773922472554,0.6984707313156334,-0.12869256222156378,1.8868431098527443,3.8925314743339694,2.281995142154195,-0.6769882967991228,0.7573477339359754,0.018407995915568375,-0.6769882967991228,1.0450737766397848,1.101338722336577,-0.5885504992892956,-0.17838548918434077,2.306048494162799,0.24157788767834681,-0.21170159451326637,1.6945455888156644,-0.967495404620523,-0.24516947172325332,-0.570991623394744,0.0828583342496927,0.05070324943423878
| 3,120
|
Endopeptidase activity
| 17
| 58
| 2.215189
| 0.026747
|
O14773,Q96K76,Q16740,Q4J6C6,P42892,O43464,Q9Y4W6,Q9NZ08,P22695,Q10713,P28070,P49721,O75844,Q99436,Q5JRX3,Q96RU2,O43847
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
160,197,228,297,106,389,211,176,401,238,51,122,405,349,410,503,342
|
160,389,342,1648,405,2300,1827,1618,2443,1080,401,2715,51,731,799,2717,1829,1344,106,2355,2882,2386,122,1292,1127,1030,2558,1346,238,1218,1382,2679,228,297,410,1353,1555,2777,1040,773,1602,1667,2634,1171,594,197,503,527,349,1449,998,708,1500,176,2500,2152,2126,211
|
1.7462892988618541,1.0167852644421618,1.101338722336577,-0.16178387178475653,0.988391573395426,-0.570991623394744,-0.2619608096795884,-0.14521962532452135,-0.6592141662818555,0.21010374774524396,1.0026016209135598,-0.9121244013006663,2.681343990663541,0.5190345053695938,0.4582592999615156,-0.9121244013006663,-0.2619608096795884,0.03457322912919779,2.1238431973235943,-0.606151958922442,-1.1552214493474031,-0.623796233913705,1.9999964563754602,0.06679822788517814,0.17849600673831648,0.2572652505088006,-0.7485248627310643,0.03457322912919779,1.3901468727742385,0.11487460343449528,0.002207377438801204,-0.8754462172552409,1.4170960559577421,1.2402198321498792,0.9741550117257047,0.03457322912919779,-0.09574924303379817,-0.967495404620523,0.2572652505088006,0.48870836441780346,-0.12869256222156378,-0.16178387178475653,-0.8207773259856875,0.14675338988725495,0.6836796028570836,1.5636624440584437,0.8157706641011584,0.7719957292272027,1.101338722336577,-0.030300711303461843,0.2885413384136224,0.5492388269345314,-0.06295244245028012,1.6424561771136268,-0.6948061890014895,-0.44925278266923796,-0.4320264666261241,1.5106857256113622
| 3,120
|
Respirasome
| 16
| 46
| 2.21293
| 0.026902
|
O96000,P13073,Q6DKK2,O14548,O95169,Q9P0J0,Q96CU9,P22695,P14406,Q7KZN9,O95168,P14927,O14949,P00403,Q13423,Q9UDW1
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
65,98,167,479,609,371,141,401,19,465,555,249,58,276,60,93
|
3093,2410,479,58,2930,1336,2803,878,1758,738,555,609,1677,2204,65,276,2299,1569,1428,1711,98,19,249,1312,2182,684,717,401,2207,2381,2302,1654,3036,2304,60,1147,1947,167,465,1053,141,1357,371,93,2434,632
|
-2.243291875020247,-0.6414835578447224,0.8448142839802352,2.51931754717366,-1.2509707594161343,0.03457322912919779,-1.0232974504893133,0.38159146097785057,-0.2284164650375626,0.5038867309618552,0.7132329833227257,0.6540102092830856,-0.17838548918434077,-0.5011773922472554,2.44886013744723,1.3087302728453603,-0.570991623394744,-0.11220249635179408,-0.030300711303461843,-0.1950246665788902,2.172842799903386,3.4042217306899554,1.3631033438829987,0.05070324943423878,-0.483828027884879,0.5642956462857995,0.534151825170032,1.0026016209135598,-0.5011773922472554,-0.623796233913705,-0.570991623394744,-0.16178387178475653,-1.5663663822078633,-0.570991623394744,2.51931754717366,0.16264163820366534,-0.3295134311551762,1.6945455888156644,0.8737472783538901,0.24157788767834681,1.8614748450901437,0.03457322912919779,1.0591788621121219,2.233668543940409,-0.6414835578447224,0.6391316883481546
| 3,120
|
Abnormality of epiphysis morphology
| 14
| 57
| 2.183317
| 0.029012
|
P38435,Q96MF7,Q7LGA3,Q96HY6,P16435,P51812,P08236,Q6NUQ1,Q7RTS9,O95831,Q96L58,P40855,O75381,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
445,26,4,381,454,172,205,379,87,24,348,437,219,315
|
979,2671,1510,1281,2348,1511,933,2622,219,964,24,622,205,1379,315,454,2674,2927,1858,1344,445,1988,437,172,2020,1436,2141,732,2579,1865,2451,2389,2211,1926,2028,895,379,2896,4,87,2472,2425,1365,381,348,26,755,489,2498,1753,1907,1331,1816,1019,1787,1402,1607
|
0.2885413384136224,-0.8754462172552409,-0.07933261901370642,0.06679822788517814,-0.606151958922442,-0.07933261901370642,0.3352111717576097,-0.8207773259856875,1.4573445331488604,0.30413037071405097,3.2454831822206605,0.6391316883481546,1.5106857256113622,0.002207377438801204,1.1849686248979059,0.8881725845149391,-0.8754462172552409,-1.231717470627754,-0.2787906755702021,0.03457322912919779,0.902570585002106,-0.3635249182132702,0.9169413951198621,1.6555112222855055,-0.3805901708428884,-0.030300711303461843,-0.44925278266923796,0.5190345053695938,-0.766520239175899,-0.2787906755702021,-0.6592141662818555,-0.623796233913705,-0.5011773922472554,-0.312566785682029,-0.3805901708428884,0.3661632883154021,1.0450737766397848,-1.1742685053617696,3.8925314743339694,2.281995142154195,-0.6769882967991228,-0.6414835578447224,0.018407995915568375,1.0450737766397848,1.101338722336577,3.1811140194189464,0.5038867309618552,0.8448142839802352,-0.6948061890014895,-0.21170159451326637,-0.2956592676299645,0.05070324943423878,-0.24516947172325332,0.27291968269656813,-0.2284164650375626,0.002207377438801204,-0.12869256222156378
| 3,120
|
Protein serine threonine tyrosine kinase activity
| 21
| 62
| 2.173222
| 0.029764
|
P06493,P49840,Q99640,Q96KB5,O75116,Q00536,Q9P289,P50750,Q00535,P24941,P27361,P54646,P51812,Q13464,O75962,P31751,Q7KZI7,Q13555,Q13557,Q16513,Q15418
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
129,131,654,652,521,18,542,151,154,31,551,423,172,189,203,206,472,356,493,626,127
|
815,2795,816,2348,1205,521,203,1823,2047,1883,129,983,1287,1916,2135,31,551,1407,206,1796,2353,1547,1766,2054,1738,131,702,2907,151,172,2284,423,2559,154,18,2645,1864,1218,1361,189,2082,969,356,493,784,671,127,626,1552,472,2473,652,2248,654,2802,1224,1672,1329,1160,542,2781,1020
|
0.44298832212023614,-1.0046484114833856,0.44298832212023614,-0.606151958922442,0.11487460343449528,0.7719957292272027,1.523963856715977,-0.2619608096795884,-0.3976953730192357,-0.2956592676299645,1.9499071826655876,0.2885413384136224,0.06679822788517814,-0.312566785682029,-0.44925278266923796,3.105368151447201,0.7279664846318218,-0.014028799969153467,1.5106857256113622,-0.24516947172325332,-0.606151958922442,-0.09574924303379817,-0.2284164650375626,-0.3976953730192357,-0.21170159451326637,1.9373348286481238,0.5492388269345314,-1.1933666554371067,1.7976923957350528,1.6555112222855055,-0.5534751015591063,0.9456019017002357,-0.7485248627310643,1.7848732800962697,3.4460375576629554,-0.8389541891155845,-0.2787906755702021,0.11487460343449528,0.018407995915568375,1.5900158562501612,-0.41484073446716224,0.30413037071405097,1.0732579772137116,0.8303063613261049,0.47349926724163727,0.5793224179068317,1.9624594510337707,0.6391316883481546,-0.09574924303379817,0.8592945504534439,-0.6769882967991228,0.6092863520442148,-0.5185682109135206,0.6092863520442148,-1.0046484114833856,0.11487460343449528,-0.16178387178475653,0.05070324943423878,0.16264163820366534,0.7573477339359754,-0.967495404620523,0.27291968269656813
| 3,120
|
Organelle envelope lumen
| 15
| 38
| 2.17054
| 0.029966
|
P78537,Q9BPX6,Q9Y5J9,Q9NR28,O60313,O43464,Q8IYU8,Q96AY3,O14925,P07437,Q9UJZ1,Q9H4A6,O95831,P36551,Q16891
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
374,67,461,136,480,389,145,271,149,436,543,413,24,409,316
|
908,1204,149,389,1336,480,24,436,1029,2443,2207,2052,409,1186,2304,1127,1465,374,1034,316,536,1805,1839,145,1092,271,861,3083,67,708,1176,413,1559,136,543,1878,461,2071
|
0.35070324111746226,0.11487460343449528,1.8104905344165125,1.0167852644421618,0.03457322912919779,0.8448142839802352,3.2454831822206605,0.9169413951198621,0.2572652505088006,-0.6592141662818555,-0.5011773922472554,-0.3976953730192357,0.9741550117257047,0.13083109947309807,-0.570991623394744,0.17849600673831648,-0.046608532900190375,1.0450737766397848,0.2572652505088006,1.1849686248979059,0.7573477339359754,-0.24516947172325332,-0.2619608096795884,1.8360241868746086,0.21010374774524396,1.322359527263043,0.4123527679415628,-1.960285301094072,2.44886013744723,0.5492388269345314,0.14675338988725495,0.9741550117257047,-0.09574924303379817,1.9247423169719036,0.7573477339359754,-0.2787906755702021,0.8881725845149391,-0.3976953730192357
| 3,120
|
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling
| 7
| 10
| 2.170214
| 0.029991
|
Q12959,Q13555,P51812,Q13557,Q14168,P07196,Q15418
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
484,356,172,493,433,22,127
|
22,551,1407,172,484,356,493,433,2026,127
|
3.30934871430298,0.7279664846318218,-0.014028799969153467,1.6555112222855055,0.8448142839802352,1.0732579772137116,0.8303063613261049,0.931285129418382,-0.3805901708428884,1.9624594510337707
| 3,120
|
Parkinsons disease
| 21
| 57
| 2.160572
| 0.030728
|
P00846,P21796,O43464,P24539,P22695,P14406,P00403,P25705,P06576,P45880,O95168,Q9Y277,O14949,O96000,O75947,Q9UDW1,P13073,O14548,O95169,Q9Y6M9,P14927
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
7,8,389,523,401,19,276,533,156,45,555,319,58,65,570,93,98,479,609,632,249
|
3093,2410,479,58,389,2930,1336,2803,878,1758,738,570,555,609,1677,2204,65,276,7,2299,2605,156,1569,1428,1711,2256,2657,98,19,249,1312,2182,684,8,717,2857,401,523,533,2207,2381,2302,624,45,1654,2105,3036,2304,857,2057,2112,1147,1947,3083,93,319,632
|
-2.243291875020247,-0.6414835578447224,0.8448142839802352,2.51931754717366,1.0167852644421618,-1.2509707594161343,0.03457322912919779,-1.0232974504893133,0.38159146097785057,-0.2284164650375626,0.5038867309618552,0.6984707313156334,0.7132329833227257,0.6540102092830856,-0.17838548918434077,-0.5011773922472554,2.44886013744723,1.3087302728453603,3.813122404253874,-0.570991623394744,-0.8026462174024811,1.772033110463191,-0.11220249635179408,-0.030300711303461843,-0.1950246665788902,-0.5360007060205642,-0.8571770657812502,2.172842799903386,3.4042217306899554,1.3631033438829987,0.05070324943423878,-0.483828027884879,0.5642956462857995,3.813122404253874,0.534151825170032,-1.1172794037264824,1.0026016209135598,0.7719957292272027,0.7573477339359754,-0.5011773922472554,-0.623796233913705,-0.570991623394744,0.6391316883481546,2.7838025090073337,-0.16178387178475653,-0.4320264666261241,-1.5663663822078633,-0.570991623394744,0.4123527679415628,-0.3976953730192357,-0.4320264666261241,0.16264163820366534,-0.3295134311551762,-1.960285301094072,2.233668543940409,1.1849686248979059,0.6391316883481546
| 3,120
|
Cardiac muscle contraction
| 11
| 22
| 2.160174
| 0.030759
|
P16615,P67936,P13073,P14927,P22695,P14406,P09493,P06753,O14949,P00403,Q9UDW1
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
444,225,98,249,401,19,184,220,58,276,93
|
479,58,276,1544,1077,220,1569,184,1428,1711,98,19,249,1312,444,684,401,2302,1654,2577,225,93
|
0.8448142839802352,2.51931754717366,1.3087302728453603,-0.09574924303379817,0.21010374774524396,1.443951626246411,-0.11220249635179408,1.6031591235667995,-0.030300711303461843,-0.1950246665788902,2.172842799903386,3.4042217306899554,1.3631033438829987,0.05070324943423878,0.902570585002106,0.5642956462857995,1.0026016209135598,-0.570991623394744,-0.16178387178475653,-0.766520239175899,1.4170960559577421,2.233668543940409
| 3,120
|
Action tremor
| 16
| 55
| 2.137265
| 0.032576
|
O14773,O75027,O95140,Q99720,P00846,P41440,Q8NC56,P20700,Q15233,P35637,Q9Y4W6,Q9NR77,Q5JRX3,Q9H6K4,Q9UBB4,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,161,481,102,7,482,368,231,333,174,211,85,410,121,477,378
|
1706,160,2527,1280,665,161,878,1123,2573,481,1791,7,2299,2766,1427,2606,2379,1916,231,966,2716,2851,174,482,1289,1290,1085,2262,1433,639,378,333,410,2144,2491,2598,1492,2544,368,2801,3083,1223,102,1252,121,1228,539,85,737,1401,477,1332,1424,1727,211
|
-0.1950246665788902,1.7462892988618541,-0.7305742271780316,0.06679822788517814,0.5793224179068317,1.7462892988618541,0.38159146097785057,0.17849600673831648,-0.766520239175899,0.8448142839802352,-0.24516947172325332,3.813122404253874,-0.570991623394744,-0.967495404620523,-0.030300711303461843,-0.8026462174024811,-0.623796233913705,-0.312566785682029,1.4036332115706927,0.30413037071405097,-0.9121244013006663,-1.0983838132255241,1.6424561771136268,0.8448142839802352,0.06679822788517814,0.06679822788517814,0.21010374774524396,-0.5360007060205642,-0.030300711303461843,0.6242237793066672,1.0450737766397848,1.1293168573183845,0.9741550117257047,-0.44925278266923796,-0.6948061890014895,-0.7845606066334213,-0.06295244245028012,-0.7305742271780316,1.0591788621121219,-1.0046484114833856,-1.960285301094072,0.11487460343449528,2.1483809702874805,0.09888373702173922,2.01246909431283,0.11487460343449528,0.7573477339359754,2.306048494162799,0.5190345053695938,0.002207377438801204,0.8592945504534439,0.05070324943423878,-0.014028799969153467,-0.1950246665788902,1.5106857256113622
| 3,120
|
Anion transmembrane transport
| 10
| 41
| 2.121243
| 0.033901
|
Q9UJS0,P30825,P41440,P21796,Q9H2D1,P45880,Q9BQT8,P08183,Q9UHG3,Q9Y277
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
490,35,482,8,76,45,467,116,23,319
|
2007,2375,982,1913,1961,2605,1341,116,1005,2256,2657,8,35,482,45,1768,2769,743,868,2163,990,969,1269,1221,1468,1660,517,995,1070,467,1583,76,1605,1673,2091,761,23,490,319,1455,850
|
-0.3805901708428884,-0.623796233913705,0.2885413384136224,-0.312566785682029,-0.34649940710130533,-0.8026462174024811,0.03457322912919779,2.0373552452822294,0.27291968269656813,-0.5360007060205642,-0.8571770657812502,3.813122404253874,3.0179282568081494,0.8448142839802352,2.7838025090073337,-0.2284164650375626,-0.967495404620523,0.5038867309618552,0.3969879056771085,-0.46651989752259204,0.2885413384136224,0.30413037071405097,0.0828583342496927,0.11487460343449528,-0.046608532900190375,-0.16178387178475653,0.786615468427979,0.2885413384136224,0.2258574389042269,0.8737472783538901,-0.11220249635179408,2.3658651509983173,-0.12869256222156378,-0.16178387178475653,-0.41484073446716224,0.5038867309618552,3.30934871430298,0.8448142839802352,1.1849686248979059,-0.030300711303461843,0.42768619226574317
| 3,120
|
Glycoprotein biosynthetic process
| 12
| 51
| 2.110919
| 0.034779
|
O60476,O43505,Q7LGA3,O15118,Q8NCH0,Q99653,Q96JB2,Q16706,Q99805,Q9H4A6,Q96L58,O60502
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,97,4,253,99,330,137,393,382,413,348,284
|
2319,253,1880,97,64,284,933,2938,2008,888,1822,443,1209,3100,1106,2830,1315,2510,2110,937,1626,732,2081,1067,745,560,918,1684,1297,393,1529,4,1629,972,99,2148,773,137,348,330,382,1537,1997,1473,1604,413,605,1000,847,1330,2653
|
-0.5885504992892956,1.3495459683507376,-0.2956592676299645,2.185045399787535,2.47241511073889,1.2813992197433883,0.3352111717576097,-1.2702763896857583,-0.3805901708428884,0.3661632883154021,-0.2619608096795884,0.902570585002106,0.11487460343449528,-2.287882511432583,0.1943166566085935,-1.0607420152216576,0.05070324943423878,-0.7126680845484551,-0.4320264666261241,0.3352111717576097,-0.14521962532452135,0.5190345053695938,-0.41484073446716224,0.2258574389042269,0.5038867309618552,0.7132329833227257,0.35070324111746226,-0.17838548918434077,0.06679822788517814,1.0167852644421618,-0.07933261901370642,3.8925314743339694,-0.14521962532452135,0.30413037071405097,2.1606213451595866,-0.44925278266923796,0.48870836441780346,1.8994965305939528,1.101338722336577,1.1432677072413866,1.0450737766397848,-0.07933261901370642,-0.3635249182132702,-0.046608532900190375,-0.12869256222156378,0.9741550117257047,0.6688594713374666,0.2885413384136224,0.42768619226574317,0.05070324943423878,-0.8389541891155845
| 3,120
|
Abnormality of the larynx
| 15
| 48
| 2.1069
| 0.035126
|
Q9UHD9,Q9UHX1,P02545,Q13501,P21964,P16435,P35637,Q92804,Q69YQ0,Q13510,Q96HY6,Q9UQN3,P43243,Q15165,P36543
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
192,388,119,552,355,454,174,113,179,440,381,582,500,27,373
|
2527,1121,2348,2622,1791,1883,119,1732,2993,1008,454,2674,355,880,2593,174,373,1344,2159,500,855,1830,2699,2326,2018,639,1409,552,440,575,2389,2211,27,733,179,2472,1365,1631,113,1152,381,1223,1539,1401,1907,192,388,582
|
-0.7305742271780316,0.17849600673831648,-0.606151958922442,-0.8207773259856875,-0.24516947172325332,-0.2956592676299645,2.01246909431283,-0.21170159451326637,-1.426644682165865,0.27291968269656813,0.8881725845149391,-0.8754462172552409,1.0732579772137116,0.38159146097785057,-0.7845606066334213,1.6424561771136268,1.0450737766397848,0.03457322912919779,-0.46651989752259204,0.8157706641011584,0.4123527679415628,-0.2619608096795884,-0.8937619071209996,-0.5885504992892956,-0.3805901708428884,0.6242237793066672,-0.014028799969153467,0.7279664846318218,0.9169413951198621,0.6984707313156334,-0.623796233913705,-0.5011773922472554,3.1703362354359217,0.5190345053695938,1.6293792007188093,-0.6769882967991228,0.018407995915568375,-0.14521962532452135,2.062163025553647,0.16264163820366534,1.0450737766397848,0.11487460343449528,-0.07933261901370642,0.002207377438801204,-0.2956592676299645,1.5900158562501612,1.0309426134342197,0.6984707313156334
| 3,120
|
Negative regulation of response to external stimulus
| 7
| 45
| 2.10633
| 0.035176
|
Q8IXJ6,P80303,Q07021,P00813,P28070,P46108,Q9UMX5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,3,233,11,51,86,25
|
2127,815,267,1585,2713,1731,11,557,2824,820,2013,1886,965,2892,51,2484,1163,86,2918,868,2108,1166,3057,3,1864,233,1410,1868,1552,1488,2064,33,2397,1152,2859,652,1071,1001,2461,678,2744,25,1508,2152,1099
|
-0.44925278266923796,0.44298832212023614,1.322359527263043,-0.12869256222156378,-0.9121244013006663,-0.21170159451326637,3.682438533398048,0.7132329833227257,-1.0419952231737202,0.44298832212023614,-0.3805901708428884,-0.2956592676299645,0.30413037071405097,-1.1742685053617696,2.681343990663541,-0.6948061890014895,0.14675338988725495,2.281995142154195,-1.2125162070669009,0.3969879056771085,-0.4320264666261241,0.14675338988725495,-1.688379149997139,3.912265751114164,-0.2787906755702021,1.4036332115706927,-0.014028799969153467,-0.2787906755702021,-0.09574924303379817,-0.06295244245028012,-0.3976953730192357,3.039876688867029,-0.623796233913705,0.16264163820366534,-1.1172794037264824,0.6092863520442148,0.2258574389042269,0.2885413384136224,-0.6592141662818555,0.5793224179068317,-0.9305339680832876,3.2026269145058173,-0.06295244245028012,-0.44925278266923796,0.21010374774524396
| 3,120
|
Intrinsic component of mitochondrial inner membrane
| 14
| 32
| 2.102822
| 0.035481
|
Q9Y2R0,Q5XKP0,O43819,Q15070,Q6P4A7,O60830,Q9Y6N1,Q13505,Q9Y4W6,Q9NX63,O14925,Q53H12,Q16891,O75431
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,578,514,170,456,14,303,47,211,148,149,536,316,313
|
149,514,14,313,608,1961,1988,1186,2163,47,170,1133,316,536,578,456,1273,693,1722,1070,2343,1981,1673,808,2091,810,148,1331,0,211,2225,303
|
1.8104905344165125,0.786615468427979,3.662148863096418,1.1849686248979059,0.6540102092830856,-0.34649940710130533,-0.3635249182132702,0.13083109947309807,-0.46651989752259204,2.7384264660489417,1.6815558467757523,0.17849600673831648,1.1849686248979059,0.7573477339359754,0.6984707313156334,0.8881725845149391,0.0828583342496927,0.5642956462857995,-0.1950246665788902,0.2258574389042269,-0.5885504992892956,-0.34649940710130533,-0.16178387178475653,0.4582592999615156,-0.41484073446716224,0.4582592999615156,1.8232677727408004,0.05070324943423878,4.674789402306948,1.5106857256113622,-0.5011773922472554,1.226444230698108
| 3,120
|
Hepatic failure
| 18
| 48
| 2.091632
| 0.036471
|
Q9H9E3,P16930,O15118,O43772,P00846,P09622,P22830,Q10713,P01889,Q13510,O95453,O75648,Q6NUQ1,Q16836,P40855,O75381,Q9P2J5,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
489,739,253,39,7,610,12,238,557,440,556,715,379,640,437,219,711,159
|
2252,253,39,1511,2856,219,715,1238,556,7,557,2299,2824,1286,1733,1569,610,739,12,159,2157,881,767,2825,437,2383,2609,1682,1085,2644,858,238,1218,440,1869,640,379,2517,1173,2035,1371,489,1874,2588,711,1177,1507,2436
|
-0.5360007060205642,1.3495459683507376,2.8849739127891,-0.07933261901370642,-1.1172794037264824,1.4573445331488604,0.534151825170032,0.09888373702173922,0.7132329833227257,3.813122404253874,0.7132329833227257,-0.570991623394744,-1.0419952231737202,0.06679822788517814,-0.21170159451326637,-0.11220249635179408,0.6540102092830856,0.5038867309618552,3.682438533398048,1.7591718093586464,-0.46651989752259204,0.38159146097785057,0.48870836441780346,-1.0419952231737202,0.9169413951198621,-0.623796233913705,-0.8026462174024811,-0.17838548918434077,0.21010374774524396,-0.8389541891155845,0.4123527679415628,1.3901468727742385,0.11487460343449528,0.9169413951198621,-0.2787906755702021,0.6242237793066672,1.0450737766397848,-0.7126680845484551,0.14675338988725495,-0.3805901708428884,0.018407995915568375,0.8448142839802352,-0.2787906755702021,-0.766520239175899,0.5492388269345314,0.14675338988725495,-0.06295244245028012,-0.6414835578447224
| 3,120
|
Hypertrophic cardiomyopathy hcm
| 6
| 11
| 2.087314
| 0.03686
|
P67936,P54646,P50402,P09493,P02545,P06753
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
225,423,212,184,119,220
|
119,1341,220,1064,184,444,212,1294,423,225,2359
|
2.01246909431283,0.03457322912919779,1.443951626246411,0.2258574389042269,1.6031591235667995,0.902570585002106,1.497384815530289,0.06679822788517814,0.9456019017002357,1.4170960559577421,-0.606151958922442
| 3,120
|
Subsets and Splits
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