term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Regulation of rna splicing
| 31
| 86
| 2.643064
| 0.008216
|
Q9UHX1,P51114,P38159,P52756,P62995,P84103,Q15007,Q9BWF3,Q07021,P55795,Q07955,P51116,P98179,P98175,Q9Y580,P31942,Q13247,Q9Y2W1,P61978,P22626,Q14011,Q16629,Q5BKZ1,Q15427,Q13243,Q13242,Q13573,P19338,Q13595,Q96MU7,P35637
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
397,391,140,263,265,521,152,547,408,404,293,290,48,426,315,424,570,329,322,321,81,227,616,490,503,234,613,241,242,642,248
|
652,1431,2013,803,1480,1338,1339,1156,3039,2303,1635,241,321,1390,737,1033,2256,1871,424,1252,248,140,956,920,391,290,957,263,1165,2218,404,322,2310,265,521,426,48,2660,2581,408,1168,293,774,2068,741,742,885,234,503,570,613,242,81,1832,2759,152,1452,490,840,227,890,3067,616,1601,2271,933,1182,2185,2873,1566,642,643,2526,1320,1274,547,2191,1146,853,1705,397,1328,1666,329,315,2086
|
0.5445741216866079,0.011755338385683791,-0.3217563066408477,0.42302785571210444,-0.015166862701093613,0.06514870608694326,0.06514870608694326,0.17017548246536693,-1.712329994309814,-0.4976220214613302,-0.09685523182921355,1.2145771446757452,0.979856683830239,0.038526658332115674,0.47202132781882844,0.24745340385816628,-0.46786141367036915,-0.23617802356071166,0.8241310428665671,0.11795129526109982,1.172767077784285,1.6323249879473072,0.298283282312465,0.32349580032456454,0.8691530690352253,1.0665769311873845,0.298283282312465,1.1305797371850148,0.17017548246536693,-0.4382834749199662,0.8466959209611702,0.979856683830239,-0.4976220214613302,1.1305797371850148,0.709655477037906,0.8241310428665671,2.801929332566857,-0.8057719361207141,-0.7112482098625537,0.8466959209611702,0.17017548246536693,1.0665769311873845,0.4475879086837396,-0.35062453129738713,0.47202132781882844,0.47202132781882844,0.3485751885508132,1.2353427068536198,0.7327741710393836,0.6396116988763457,0.5923317961811347,1.2145771446757452,2.2042035774756688,-0.20798764245173287,-0.9347396848564197,1.555594300107399,0.011755338385683791,0.75578003326324,0.39833990773856,1.256016338166523,0.3485751885508132,-1.9879928242428384,0.5923317961811347,-0.0694704733838678,-0.46786141367036915,0.32349580032456454,0.17017548246536693,-0.4088860728488319,-1.1009154766800557,-0.042241579625993585,0.5685132566383815,0.5685132566383815,-0.6492423972397605,0.0916230653837448,0.11795129526109982,0.6864228881683501,-0.4088860728488319,0.19607443889255075,0.39833990773856,-0.12439757025387724,0.8691530690352253,0.0916230653837448,-0.09685523182921355,0.979856683830239,1.023417311456126,-0.35062453129738713
| 3,120
|
Plasma membrane organization
| 6
| 31
| 2.635695
| 0.008397
|
Q9UQN3,Q96CP7,Q9Y3E7,P41440,Q9UQB8,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
132,9,203,73,13,183
|
1149,802,878,1482,452,183,881,73,1303,1724,684,2223,1169,2069,1001,779,2486,9,2954,2192,260,1024,1413,1147,1283,13,132,447,1027,203,2600
|
0.17017548246536693,0.42302785571210444,0.3485751885508132,-0.015166862701093613,0.8014574420423553,1.4380669400587471,0.3485751885508132,2.3039419144770994,0.0916230653837448,-0.15209923198018688,0.5205132181705904,-0.4382834749199662,0.17017548246536693,-0.35062453129738713,0.2729362763877655,0.4475879086837396,-0.6185351182463072,4.397449673808894,-1.3081044921965708,-0.4088860728488319,1.1517209730784248,0.2729362763877655,0.038526658332115674,0.19607443889255075,0.11795129526109982,4.164591374905695,1.7078061122023387,0.8241310428665671,0.2729362763877655,1.3378069158806978,-0.7112482098625537
| 3,120
|
Fasciculations
| 14
| 40
| 2.632427
| 0.008478
|
P04792,Q9UQN3,P07196,P51114,P22626,Q13510,P06280,O43819,Q9BQT8,O95831,P35637,Q8TD16,Q13501,Q92734
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,132,103,391,321,44,232,239,480,86,248,188,382,386
|
2774,239,1295,86,128,232,103,829,3002,1339,2254,321,248,391,2398,2264,1221,382,44,714,2227,2183,2641,188,386,1185,1605,900,1660,480,2189,1189,1469,852,795,2081,2372,1614,132,533
|
-0.9675239012000673,1.2145771446757452,0.0916230653837448,2.119398055387944,1.7264856813353782,1.2353427068536198,1.9271271193823978,0.39833990773856,-1.4877287999834443,0.06514870608694326,-0.46786141367036915,0.979856683830239,1.172767077784285,0.8691530690352253,-0.5576999615504026,-0.46786141367036915,0.14413493056950505,0.8915034664671595,2.860509873296997,0.4963293559988893,-0.4382834749199662,-0.4088860728488319,-0.7740586736982547,1.4380669400587471,0.8915034664671595,0.17017548246536693,-0.0694704733838678,0.3485751885508132,-0.09685523182921355,0.7786741122076469,-0.4088860728488319,0.17017548246536693,0.011755338385683791,0.39833990773856,0.4475879086837396,-0.35062453129738713,-0.5275674680675104,-0.0694704733838678,1.7078061122023387,0.709655477037906
| 3,120
|
Mitochondrial biogenesis
| 12
| 35
| 2.631534
| 0.0085
|
Q16891,Q04837,O75947,Q13505,Q5XKP0,Q9NX63,O75964,P00846,P48735,P06576,P36542,P24539
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
355,292,252,76,208,312,114,52,306,422,305,94
|
1860,2091,464,252,114,1531,52,1205,422,94,919,305,1542,955,306,2394,1443,633,2849,883,610,292,76,2352,2870,355,208,1745,1505,2321,1606,2045,821,312,702
|
-0.23617802356071166,-0.37966711166030426,0.7786741122076469,1.1517209730784248,1.818768282448762,-0.042241579625993585,2.7276227820437797,0.14413493056950505,0.8241310428665671,2.050407604865225,0.32349580032456454,1.023417311456126,-0.042241579625993585,0.298283282312465,1.023417311456126,-0.5576999615504026,0.011755338385683791,0.5685132566383815,-1.0672234487170145,0.3485751885508132,0.5923317961811347,1.0665769311873845,2.2376915434747073,-0.5275674680675104,-1.1009154766800557,0.9358878616746352,1.3174933512024687,-0.15209923198018688,-0.015166862701093613,-0.4976220214613302,-0.0694704733838678,-0.3217563066408477,0.42302785571210444,1.023417311456126,0.5205132181705904
| 3,120
|
Negative regulation of mrna splicing via spliceosome
| 12
| 16
| 2.629987
| 0.008539
|
O00422,Q16629,P61978,P22626,P38159,Q13242,P98175,P26368,O75494,Q08170,Q07021,Q13247
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
652,227,322,321,140,234,426,737,803,774,408,570
|
652,803,321,737,1033,140,322,426,408,774,885,234,570,1452,227,1274
|
0.5445741216866079,0.42302785571210444,0.979856683830239,0.47202132781882844,0.24745340385816628,1.6323249879473072,0.979856683830239,0.8241310428665671,0.8466959209611702,0.4475879086837396,0.3485751885508132,1.2353427068536198,0.6396116988763457,0.011755338385683791,1.256016338166523,0.11795129526109982
| 3,120
|
Regulation of mrna splicing via spliceosome
| 25
| 62
| 2.618228
| 0.008839
|
Q9UHX1,P51114,P38159,P52756,P62995,P84103,Q15007,Q9BWF3,Q07021,P51116,P98179,P98175,Q9Y580,Q13247,Q9Y2W1,P61978,P22626,Q14011,Q16629,Q15427,Q13242,Q13573,P19338,Q13595,Q96MU7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
397,391,140,263,265,521,152,547,408,290,48,426,315,570,329,322,321,81,227,490,234,613,241,242,642
|
652,803,1480,1338,1339,1156,3039,2303,1635,241,321,737,1033,2256,1871,140,920,391,290,263,1165,322,265,521,426,48,2660,408,1168,774,2068,885,234,570,613,242,81,1832,152,1452,490,840,227,890,3067,2271,933,2185,2873,1566,642,643,2526,1320,1274,547,2191,397,1666,329,315,2086
|
0.5445741216866079,0.42302785571210444,-0.015166862701093613,0.06514870608694326,0.06514870608694326,0.17017548246536693,-1.712329994309814,-0.4976220214613302,-0.09685523182921355,1.2145771446757452,0.979856683830239,0.47202132781882844,0.24745340385816628,-0.46786141367036915,-0.23617802356071166,1.6323249879473072,0.32349580032456454,0.8691530690352253,1.0665769311873845,1.1305797371850148,0.17017548246536693,0.979856683830239,1.1305797371850148,0.709655477037906,0.8241310428665671,2.801929332566857,-0.8057719361207141,0.8466959209611702,0.17017548246536693,0.4475879086837396,-0.35062453129738713,0.3485751885508132,1.2353427068536198,0.6396116988763457,0.5923317961811347,1.2145771446757452,2.2042035774756688,-0.20798764245173287,1.555594300107399,0.011755338385683791,0.75578003326324,0.39833990773856,1.256016338166523,0.3485751885508132,-1.9879928242428384,-0.46786141367036915,0.32349580032456454,-0.4088860728488319,-1.1009154766800557,-0.042241579625993585,0.5685132566383815,0.5685132566383815,-0.6492423972397605,0.0916230653837448,0.11795129526109982,0.6864228881683501,-0.4088860728488319,0.8691530690352253,-0.09685523182921355,0.979856683830239,1.023417311456126,-0.35062453129738713
| 3,120
|
Protein targeting to mitochondrion
| 11
| 48
| 2.616063
| 0.008895
|
Q15388,Q8N4H5,Q10713,O14925,Q9P0J0,O60830,O14737,O95831,Q9NS69,Q5JRX3,P55786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
294,70,105,171,313,176,211,86,261,307,29
|
2291,2203,211,171,1379,1030,176,1335,1814,1629,332,1909,86,1631,1436,1715,2386,2628,1779,1397,2576,862,29,1493,105,294,1792,841,586,307,2316,70,2232,1365,1101,1369,510,648,972,261,313,2416,1764,1027,1110,702,2719,3090
|
-0.4976220214613302,-0.4382834749199662,1.297090899466863,1.4775738794299105,0.038526658332115674,0.24745340385816628,1.4578623634759529,0.06514870608694326,-0.20798764245173287,-0.09685523182921355,0.9579237536502591,-0.2645349940023304,2.119398055387944,-0.09685523182921355,0.011755338385683791,-0.15209923198018688,-0.5576999615504026,-0.7740586736982547,-0.17996198897025922,0.038526658332115674,-0.7112482098625537,0.37352278495630703,3.3430496340161606,-0.015166862701093613,1.9092431533941194,1.0665769311873845,-0.17996198897025922,0.39833990773856,0.616030896851247,1.023417311456126,-0.4976220214613302,2.3692468623114746,-0.4382834749199662,0.06514870608694326,0.22183326505174678,0.06514870608694326,0.7327741710393836,0.5685132566383815,0.298283282312465,1.1517209730784248,1.023417311456126,-0.5576999615504026,-0.15209923198018688,0.2729362763877655,0.22183326505174678,0.5205132181705904,-0.8698275055005745,-2.499432291736275
| 3,120
|
Negative regulation of mrna processing
| 15
| 23
| 2.614468
| 0.008937
|
O00422,Q16629,Q5VTR2,P61978,P22626,P38159,Q13242,O75150,P98175,O00267,P26368,Q6PJT7,Q08170,Q07021,Q13247
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
652,227,617,322,321,140,234,484,426,800,737,664,774,408,570
|
800,652,484,803,2459,321,737,1033,140,1083,322,426,408,774,885,234,570,1452,227,617,1948,664,1274
|
0.42302785571210444,0.5445741216866079,0.75578003326324,0.42302785571210444,-0.6185351182463072,0.979856683830239,0.47202132781882844,0.24745340385816628,1.6323249879473072,0.22183326505174678,0.979856683830239,0.8241310428665671,0.8466959209611702,0.4475879086837396,0.3485751885508132,1.2353427068536198,0.6396116988763457,0.011755338385683791,1.256016338166523,0.5923317961811347,-0.2645349940023304,0.5445741216866079,0.11795129526109982
| 3,120
|
transporter
| 17
| 55
| 2.612037
| 0.009
|
O43772,Q8N1F7,Q9HD45,Q567V2,P52292,Q15070,P57740,P41440,O60830,Q9NR77,Q9C0E2,Q8NFH4,O00629,Q6N075,Q7Z3B4,Q99805,Q9H2D1
|
Functions
|
Panther Protein class
|
panther_protein_class
|
1,460,199,38,455,104,393,73,176,126,246,308,146,54,385,154,61
|
1521,2205,146,3072,2803,906,1030,1768,1,176,908,2456,834,568,73,1821,1257,455,2027,1165,2706,2397,2028,2104,2882,393,2633,1127,1651,104,38,54,2552,385,460,308,935,2184,1694,1361,1659,1892,594,154,1954,2667,246,61,2743,199,126,2419,2933,512,2969
|
-0.042241579625993585,-0.4382834749199662,1.5748962832288216,-2.1110040441905302,-1.000530653277979,0.32349580032456454,0.24745340385816628,-0.17996198897025922,5.144282894154371,1.4578623634759529,0.32349580032456454,-0.6185351182463072,0.39833990773856,0.6396116988763457,2.3039419144770994,-0.20798764245173287,0.11795129526109982,0.8014574420423553,-0.3217563066408477,0.17017548246536693,-0.8698275055005745,-0.5576999615504026,-0.3217563066408477,-0.37966711166030426,-1.1348420125464262,0.8691530690352253,-0.7740586736982547,0.19607443889255075,-0.09685523182921355,1.9271271193823978,3.101343321075666,2.6975560940099816,-0.6801459566044995,0.8915034664671595,0.8014574420423553,1.023417311456126,0.32349580032456454,-0.4088860728488319,-0.12439757025387724,0.06514870608694326,-0.09685523182921355,-0.23617802356071166,0.616030896851247,1.555594300107399,-0.2645349940023304,-0.8057719361207141,1.193718866633161,2.4813316430188412,-0.902175152364751,1.3580323311839413,1.763620063558507,-0.5576999615504026,-1.238060398252917,0.7327741710393836,-1.3435062986012638
| 3,120
|
Aplasia hypoplasia involving the vertebral column
| 11
| 16
| 2.608878
| 0.009084
|
Q7RTS9,Q8TAA9,Q9H9E3,Q96HY6,Q6NUQ1,Q14739,O95831,P08236,P39019,P04066,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,131,793,528,663,746,86,247,425,282,283
|
2088,2014,86,282,247,807,283,1302,425,746,1687,663,32,131,528,793
|
-0.37966711166030426,-0.3217563066408477,2.119398055387944,1.0880085580638097,1.172767077784285,0.42302785571210444,1.0880085580638097,0.0916230653837448,0.8241310428665671,0.47202132781882844,-0.12439757025387724,0.5445741216866079,3.210375491197299,1.7078061122023387,0.709655477037906,0.4475879086837396
| 3,120
|
Disproportionate short limb short stature
| 6
| 20
| 2.608776
| 0.009087
|
Q7RTS9,Q6DKJ4,Q15392,Q32P28,Q7LGA3,Q96MF7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,220,130,74,19,162
|
950,1377,2014,346,807,1638,2466,1304,1684,746,130,74,220,19,32,2073,162,2888,1322,2597
|
0.298283282312465,0.038526658332115674,-0.3217563066408477,0.9358878616746352,0.42302785571210444,-0.09685523182921355,-0.6185351182463072,0.0916230653837448,-0.12439757025387724,0.47202132781882844,1.7078061122023387,2.3039419144770994,1.2765988138362,3.9302356800799503,3.210375491197299,-0.35062453129738713,1.5362117181364128,-1.1348420125464262,0.0916230653837448,-0.7112482098625537
| 3,120
|
Ectrodactyly
| 6
| 17
| 2.604073
| 0.009212
|
P04792,Q6DKJ4,Q99720,P07196,P48449,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,220,6,103,299,126
|
909,347,128,103,299,1592,1826,1942,1556,1455,220,2232,6,126,2797,2597,533
|
0.32349580032456454,0.9358878616746352,1.7264856813353782,1.9271271193823978,1.0450468054585367,-0.0694704733838678,-0.20798764245173287,-0.2645349940023304,-0.042241579625993585,0.011755338385683791,1.2765988138362,-0.4382834749199662,4.647892361308431,1.763620063558507,-0.9675239012000673,-0.7112482098625537,0.709655477037906
| 3,120
|
Carbohydrate derivative catabolic process
| 12
| 36
| 2.576007
| 0.009995
|
A8MXV4,Q9NUJ1,P36639,Q9H773,P54802,P06280,P15586,Q13126,P08236,P04066,P16278,P17900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
155,167,135,175,264,232,111,20,247,282,283,190
|
155,1963,563,2571,2426,1070,1773,282,232,400,829,247,1438,111,283,190,2060,2724,3010,3031,135,1927,2576,2216,264,2223,20,1691,2320,1953,309,1188,2875,175,167,1375
|
1.5362117181364128,-0.29306044672954845,0.6396116988763457,-0.7112482098625537,-0.5880217491572218,0.22183326505174678,-0.17996198897025922,1.0880085580638097,1.2353427068536198,0.8466959209611702,0.39833990773856,1.172767077784285,0.011755338385683791,1.8370056925799199,1.0880085580638097,1.4181869234230973,-0.35062453129738713,-0.902175152364751,-1.5244569016571512,-1.6363177401147757,1.6702193073777245,-0.2645349940023304,-0.7112482098625537,-0.4382834749199662,1.1305797371850148,-0.4382834749199662,3.7786917531689994,-0.12439757025387724,-0.4976220214613302,-0.2645349940023304,1.023417311456126,0.17017548246536693,-1.1009154766800557,1.4775738794299105,1.516747891198495,0.06514870608694326
| 3,120
|
Late endosome membrane
| 8
| 34
| 2.573439
| 0.010069
|
Q14108,Q9UQN3,Q8IV08,Q9Y3E7,Q9H9H4,O95772,Q9HD42,O15118
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
67,132,39,203,311,50,260,95
|
2564,1376,95,1336,50,828,1482,2149,1484,2064,1876,2217,67,2549,1499,39,2486,693,723,941,387,2128,2920,2192,311,260,1024,1413,2415,1853,2008,132,1616,203
|
-0.7112482098625537,0.038526658332115674,2.0329969890041335,0.06514870608694326,2.7723526302969184,0.39833990773856,-0.015166862701093613,-0.4088860728488319,-0.015166862701093613,-0.35062453129738713,-0.23617802356071166,-0.4382834749199662,2.385428384194839,-0.6801459566044995,-0.015166862701093613,3.0875268139564396,-0.6185351182463072,0.5205132181705904,0.4963293559988893,0.32349580032456454,0.8915034664671595,-0.37966711166030426,-1.2034112370325538,-0.4088860728488319,1.023417311456126,1.1517209730784248,0.2729362763877655,0.038526658332115674,-0.5576999615504026,-0.20798764245173287,-0.29306044672954845,1.7078061122023387,-0.0694704733838678,1.3378069158806978
| 3,120
|
Wormian bones
| 7
| 18
| 2.570279
| 0.010162
|
P02545,Q32P28,O75718,Q9Y487,O95831,O75844,Q8NC56
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,74,346,150,86,123,287
|
2204,346,123,2806,86,376,1632,2573,1638,2030,1219,1733,1684,1552,74,287,436,150
|
-0.4382834749199662,0.9358878616746352,1.763620063558507,-1.000530653277979,2.119398055387944,0.8915034664671595,-0.09685523182921355,-0.7112482098625537,-0.09685523182921355,-0.3217563066408477,0.14413493056950505,-0.15209923198018688,-0.12439757025387724,-0.042241579625993585,2.3039419144770994,1.0880085580638097,0.8241310428665671,1.5748962832288216
| 3,120
|
Positional foot deformity
| 26
| 101
| 2.568603
| 0.010211
|
P04792,P02545,Q15392,Q8TAA9,Q69YQ0,Q9UHX1,Q9Y487,Q8NI60,Q8NCH0,Q7RTS9,Q96AY3,Q96L58,Q15907,P98175,Q8TD16,P61978,P06753,P36543,P21964,Q96DF8,P07196,Q15427,O96028,P08236,Q9NR77,Q9HD42
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,376,130,131,136,397,150,413,161,32,436,166,49,426,188,322,450,213,466,100,103,490,347,247,126,260
|
2204,2454,1289,2331,2845,2503,982,627,1905,2014,2892,1588,2568,909,347,376,128,450,103,247,2209,1675,1914,1209,1917,2573,466,2155,2434,213,1302,1645,1875,2847,2216,1592,958,2470,2030,322,426,684,1548,500,1826,1733,1942,1450,1790,130,490,49,1455,136,2664,663,1997,930,32,2183,161,2073,2641,413,131,2232,188,2642,574,751,1185,591,436,100,166,2000,1319,2888,2128,970,1322,2282,793,2766,260,126,1107,1192,2597,2200,397,1193,1371,1194,762,1421,949,1110,150,2086,2934
|
-0.4382834749199662,-0.6185351182463072,0.0916230653837448,-0.5275674680675104,-1.0672234487170145,-0.6492423972397605,0.2729362763877655,0.5685132566383815,-0.2645349940023304,-0.3217563066408477,-1.169006197935009,-0.0694704733838678,-0.7112482098625537,0.32349580032456454,0.9358878616746352,0.8915034664671595,1.7264856813353782,0.8014574420423553,1.9271271193823978,1.172767077784285,-0.4382834749199662,-0.12439757025387724,-0.2645349940023304,0.14413493056950505,-0.2645349940023304,-0.7112482098625537,0.7786741122076469,-0.4088860728488319,-0.5880217491572218,1.297090899466863,0.0916230653837448,-0.09685523182921355,-0.23617802356071166,-1.0672234487170145,-0.4382834749199662,-0.0694704733838678,0.298283282312465,-0.6185351182463072,-0.3217563066408477,0.979856683830239,0.8241310428665671,0.5205132181705904,-0.042241579625993585,0.7327741710393836,-0.20798764245173287,-0.15209923198018688,-0.2645349940023304,0.011755338385683791,-0.17996198897025922,1.7078061122023387,0.75578003326324,2.801929332566857,0.011755338385683791,1.6702193073777245,-0.8057719361207141,0.5445741216866079,-0.29306044672954845,0.32349580032456454,3.210375491197299,-0.4088860728488319,1.5362117181364128,-0.35062453129738713,-0.7740586736982547,0.8466959209611702,1.7078061122023387,-0.4382834749199662,1.4380669400587471,-0.7740586736982547,0.6396116988763457,0.47202132781882844,0.17017548246536693,0.616030896851247,0.8241310428665671,1.962688195568438,1.516747891198495,-0.29306044672954845,0.0916230653837448,-1.1348420125464262,-0.37966711166030426,0.298283282312465,0.0916230653837448,-0.46786141367036915,0.4475879086837396,-0.9347396848564197,1.1517209730784248,1.763620063558507,0.22183326505174678,0.17017548246536693,-0.7112482098625537,-0.4088860728488319,0.8691530690352253,0.17017548246536693,0.06514870608694326,0.17017548246536693,0.47202132781882844,0.038526658332115674,0.32349580032456454,0.22183326505174678,1.5748962832288216,-0.35062453129738713,-1.238060398252917
| 3,120
|
Protein processing
| 11
| 45
| 2.567633
| 0.01024
|
Q15392,Q96F07,Q10713,P42892,Q9Y4W6,O75976,Q5JRX3,Q96E52,Q92896,O75503,O75844
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,325,105,43,345,177,307,179,118,27,123
|
1150,1428,1379,1814,27,768,123,177,1069,2381,2911,828,2022,1916,2302,2211,881,43,2341,3032,497,105,1988,1451,130,307,2269,2073,1180,2041,359,118,179,325,2364,644,1101,1366,2368,648,671,1662,2199,512,345
|
0.17017548246536693,0.011755338385683791,0.038526658332115674,-0.20798764245173287,3.44643436310832,0.4475879086837396,1.763620063558507,1.4578623634759529,0.22183326505174678,-0.5576999615504026,-1.2034112370325538,0.39833990773856,-0.3217563066408477,-0.2645349940023304,-0.4976220214613302,-0.4382834749199662,0.3485751885508132,2.875037373385399,-0.5275674680675104,-1.6363177401147757,0.7327741710393836,1.9092431533941194,-0.29306044672954845,0.011755338385683791,1.7078061122023387,1.023417311456126,-0.46786141367036915,-0.35062453129738713,0.17017548246536693,-0.3217563066408477,0.9358878616746352,1.8004585753415925,1.4578623634759529,0.979856683830239,-0.5275674680675104,0.5685132566383815,0.22183326505174678,0.06514870608694326,-0.5275674680675104,0.5685132566383815,0.5445741216866079,-0.09685523182921355,-0.4088860728488319,0.7327741710393836,0.9579237536502591
| 3,120
|
Glycosphingolipid metabolism
| 7
| 15
| 2.554654
| 0.010629
|
Q13510,P06280,Q8NBJ7,P10619,P16278,Q9NZD2,P17900
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
44,232,221,58,283,320,190
|
1425,1768,1773,232,400,829,58,283,190,44,221,969,2957,320,2372
|
0.011755338385683791,-0.17996198897025922,-0.17996198897025922,1.2353427068536198,0.8466959209611702,0.39833990773856,2.5128566082167416,1.0880085580638097,1.4181869234230973,2.860509873296997,1.2765988138362,0.298283282312465,-1.3081044921965708,1.001687568375461,-0.5275674680675104
| 3,120
|
Mitochondrial complex iv assembly
| 6
| 13
| 2.541762
| 0.01103
|
Q9Y2R0,P14406,P13073,Q9Y6N1,O43819,Q7KZN9
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
2,72,42,204,239,335
|
1522,239,604,913,2383,42,72,1388,349,335,3020,2,204
|
-0.042241579625993585,1.2145771446757452,0.5923317961811347,0.32349580032456454,-0.5576999615504026,2.875037373385399,2.336710950263473,0.038526658332115674,0.9358878616746352,0.9579237536502591,-1.561461734297637,4.875529536020904,1.3378069158806978
| 3,120
|
Amyotrophic lateral sclerosis
| 6
| 18
| 2.52806
| 0.011469
|
Q9UQN3,Q99720,P22626,Q15165,P35637,Q92804
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
132,6,321,112,248,153
|
1295,3002,1339,321,1871,248,861,1442,2398,1221,382,714,112,153,900,6,1327,132
|
0.0916230653837448,-1.4877287999834443,0.06514870608694326,0.979856683830239,-0.23617802356071166,1.172767077784285,0.37352278495630703,0.011755338385683791,-0.5576999615504026,0.14413493056950505,0.8915034664671595,0.4963293559988893,1.8370056925799199,1.555594300107399,0.3485751885508132,4.647892361308431,0.0916230653837448,1.7078061122023387
| 3,120
|
Positive regulation of mrna processing
| 6
| 20
| 2.522213
| 0.011662
|
P38159,P62995,Q14011,P98179,P19338,Q13595
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
140,265,81,48,241,242
|
1585,1338,1156,241,2256,140,1165,265,48,2068,613,242,81,490,865,718,1566,2281,1666,329
|
-0.0694704733838678,0.06514870608694326,0.17017548246536693,1.2145771446757452,-0.46786141367036915,1.6323249879473072,0.17017548246536693,1.1305797371850148,2.801929332566857,-0.35062453129738713,0.5923317961811347,1.2145771446757452,2.2042035774756688,0.75578003326324,0.37352278495630703,0.4963293559988893,-0.042241579625993585,-0.46786141367036915,-0.09685523182921355,0.979856683830239
| 3,120
|
Processing of smdt1
| 9
| 12
| 2.519324
| 0.011758
|
Q9BPX6,Q8NE86,Q10713,Q9Y4W6,Q9UJZ1,P35232,Q96TA2,Q9H300,Q99623
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
595,526,105,345,512,519,644,648,259
|
1814,519,105,750,526,1051,644,259,595,648,512,345
|
-0.20798764245173287,0.709655477037906,1.9092431533941194,0.47202132781882844,0.709655477037906,0.24745340385816628,0.5685132566383815,1.1517209730784248,0.616030896851247,0.5685132566383815,0.7327741710393836,0.9579237536502591
| 3,120
|
Bowing of the legs
| 11
| 49
| 2.518566
| 0.011783
|
Q7RTS9,Q96L58,Q15056,Q9NX62,Q32P28,Q9NSE4,Q7LGA3,Q13126,P08236,P16278,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,166,323,137,74,344,19,20,247,283,126
|
2204,2423,2013,2014,464,346,1712,247,2829,283,1209,1916,2573,2938,2433,2388,2389,1302,1120,998,684,1786,2916,1219,924,20,1738,323,1263,74,19,32,2523,813,2073,2642,528,166,2000,2412,126,344,2595,137,2669,1371,2134,1286,2086
|
-0.4382834749199662,-0.5880217491572218,-0.3217563066408477,-0.3217563066408477,0.7786741122076469,0.9358878616746352,-0.15209923198018688,1.172767077784285,-1.0337628479999912,1.0880085580638097,0.14413493056950505,-0.2645349940023304,-0.7112482098625537,-1.2729570159514279,-0.5880217491572218,-0.5576999615504026,-0.5576999615504026,0.0916230653837448,0.19607443889255075,0.2729362763877655,0.5205132181705904,-0.17996198897025922,-1.2034112370325538,0.14413493056950505,0.32349580032456454,3.7786917531689994,-0.15209923198018688,0.979856683830239,0.11795129526109982,2.3039419144770994,3.9302356800799503,3.210375491197299,-0.6492423972397605,0.42302785571210444,-0.35062453129738713,-0.7740586736982547,0.709655477037906,1.516747891198495,-0.29306044672954845,-0.5576999615504026,1.763620063558507,0.9579237536502591,-0.7112482098625537,1.651310887354022,-0.8057719361207141,0.06514870608694326,-0.37966711166030426,0.11795129526109982,-0.35062453129738713
| 3,120
|
Sphingolipid metabolism
| 10
| 24
| 2.513841
| 0.011942
|
P06865,P51648,Q13510,P06280,Q8NBJ7,Q06136,P10619,P16278,Q9NZD2,P17900
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
400,91,44,232,221,406,58,283,320,190
|
1425,802,979,2804,1768,1295,449,1773,232,400,829,58,283,190,2574,91,406,44,221,969,2957,320,2372,2197
|
0.011755338385683791,0.42302785571210444,0.2729362763877655,-1.000530653277979,-0.17996198897025922,0.0916230653837448,0.8014574420423553,-0.17996198897025922,1.2353427068536198,0.8466959209611702,0.39833990773856,2.5128566082167416,1.0880085580638097,1.4181869234230973,-0.7112482098625537,2.0677525498216016,0.8466959209611702,2.860509873296997,1.2765988138362,0.298283282312465,-1.3081044921965708,1.001687568375461,-0.5275674680675104,-0.4088860728488319
| 3,120
|
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
| 10
| 16
| 2.513602
| 0.011951
|
O43852,Q13217,Q07065,Q5JRA6,O76024,Q9BTY2,O43493,Q86UP2,Q15293,Q02818
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
134,197,40,384,565,309,704,688,249,30
|
704,134,565,1632,2947,1300,734,1590,30,40,197,1553,249,384,688,309
|
0.4963293559988893,1.6702193073777245,0.6396116988763457,-0.09685523182921355,-1.3081044921965708,0.0916230653837448,0.47202132781882844,-0.0694704733838678,3.3299572675677735,3.031833480450284,1.3580323311839413,-0.042241579625993585,1.172767077784285,0.8915034664671595,0.5205132181705904,1.023417311456126
| 3,120
|
Membrane lipid metabolic process
| 14
| 36
| 2.513224
| 0.011963
|
P06865,Q8NBX0,O95470,Q13510,P06280,Q96S52,P50897,Q06136,Q8NCC3,Q99805,P04066,P16278,Q9NZD2,P17900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
400,3,449,44,232,341,51,406,21,154,282,283,320,190
|
802,979,2804,1379,1769,449,1773,282,232,400,829,283,190,2574,1640,51,2223,406,1220,44,586,1455,3081,3,21,1235,506,341,3021,154,2957,2981,320,2372,974,2197
|
0.42302785571210444,0.2729362763877655,-1.000530653277979,0.038526658332115674,-0.17996198897025922,0.8014574420423553,-0.17996198897025922,1.0880085580638097,1.2353427068536198,0.8466959209611702,0.39833990773856,1.0880085580638097,1.4181869234230973,-0.7112482098625537,-0.09685523182921355,2.757491625277111,-0.4382834749199662,0.8466959209611702,0.14413493056950505,2.860509873296997,0.616030896851247,0.011755338385683791,-2.279909385621441,4.782120546298962,3.7786917531689994,0.14413493056950505,0.7327741710393836,0.9579237536502591,-1.561461734297637,1.555594300107399,-1.3081044921965708,-1.379165978216167,1.001687568375461,-0.5275674680675104,0.298283282312465,-0.4088860728488319
| 3,120
|
RNA recognition motif domain [IPR000504]
| 55
| 120
| 2.50697
| 0.012177
|
O75821,Q9UHX1,Q8WXF1,P38159,O60506,P52756,P62995,P84103,P23588,Q92804,Q9BWF3,O14979,Q08170,P55795,Q86V81,Q07955,O43390,Q9Y6M1,Q9NWH9,Q9UKM9,P09012,P98179,P98175,Q9Y580,O75494,Q8WUA2,P31942,P51991,Q13247,P33240,Q96PK6,Q15056,P22626,P07910,Q99729,Q14011,Q86U42,P78332,Q16629,Q14103,Q13151,Q15427,Q13243,Q15233,Q13242,P08579,Q8N684,P19338,Q13595,P26368,Q12849,P35637,Q9GZT3,P23246,Q01085
|
Sequence
|
InterPro Domain
|
interpro_domain
|
628,397,527,140,517,263,265,521,276,153,547,272,774,404,286,293,399,826,443,698,552,48,426,315,803,573,424,681,570,566,847,323,321,205,342,81,337,712,227,615,612,490,503,747,234,485,504,241,242,737,742,248,647,496,499
|
1148,1811,272,1965,1065,399,2248,517,803,628,1863,1480,988,205,485,1338,552,1339,1819,3039,2459,241,321,496,276,737,1033,1871,424,1252,566,248,140,1977,861,920,681,1122,957,263,404,1305,265,712,521,426,48,2169,499,923,3098,293,774,742,1221,612,234,503,570,1990,2109,242,81,615,2036,1832,2266,1879,323,747,1452,1944,490,962,227,1353,3067,1093,2357,337,286,2123,1601,2271,2856,504,573,1182,2793,527,153,2873,1011,1566,1053,847,1320,1463,342,1274,547,2593,1573,647,1146,1899,853,443,1806,1025,1026,397,1328,698,1854,2772,2376,315,2086,826
|
0.17017548246536693,-0.20798764245173287,1.1093425443192109,-0.29306044672954845,0.22183326505174678,0.8466959209611702,-0.46786141367036915,0.709655477037906,0.42302785571210444,0.5685132566383815,-0.23617802356071166,-0.015166862701093613,0.2729362763877655,1.3174933512024687,0.75578003326324,0.06514870608694326,0.6630753264781283,0.06514870608694326,-0.20798764245173287,-1.712329994309814,-0.6185351182463072,1.2145771446757452,0.979856683830239,0.7327741710393836,1.1093425443192109,0.47202132781882844,0.24745340385816628,-0.23617802356071166,0.8241310428665671,0.11795129526109982,0.6396116988763457,1.172767077784285,1.6323249879473072,-0.29306044672954845,0.37352278495630703,0.32349580032456454,0.5205132181705904,0.19607443889255075,0.298283282312465,1.1305797371850148,0.8466959209611702,0.0916230653837448,1.1305797371850148,0.4963293559988893,0.709655477037906,0.8241310428665671,2.801929332566857,-0.4088860728488319,0.7327741710393836,0.32349580032456454,-2.776256557108311,1.0665769311873845,0.4475879086837396,0.47202132781882844,0.14413493056950505,0.5923317961811347,1.2353427068536198,0.7327741710393836,0.6396116988763457,-0.29306044672954845,-0.37966711166030426,1.2145771446757452,2.2042035774756688,0.5923317961811347,-0.3217563066408477,-0.20798764245173287,-0.46786141367036915,-0.23617802356071166,0.979856683830239,0.47202132781882844,0.011755338385683791,-0.2645349940023304,0.75578003326324,0.298283282312465,1.256016338166523,0.06514870608694326,-1.9879928242428384,0.22183326505174678,-0.5275674680675104,0.9579237536502591,1.0880085580638097,-0.37966711166030426,-0.0694704733838678,-0.46786141367036915,-1.0672234487170145,0.7327741710393836,0.6396116988763457,0.17017548246536693,-0.9675239012000673,0.709655477037906,1.555594300107399,-1.1009154766800557,0.2729362763877655,-0.042241579625993585,0.24745340385816628,0.39833990773856,0.0916230653837448,0.011755338385683791,0.9579237536502591,0.11795129526109982,0.6864228881683501,-0.7112482098625537,-0.042241579625993585,0.5685132566383815,0.19607443889255075,-0.23617802356071166,0.39833990773856,0.8241310428665671,-0.17996198897025922,0.2729362763877655,0.2729362763877655,0.8691530690352253,0.0916230653837448,0.5205132181705904,-0.20798764245173287,-0.9347396848564197,-0.5275674680675104,1.023417311456126,-0.35062453129738713,0.42302785571210444
| 3,120
|
Lipid localization
| 10
| 70
| 2.500016
| 0.012419
|
P35790,O43772,O15260,P08183,Q14108,Q99720,Q9H6V9,Q8WTV0,P31751,O15118
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,157,64,67,6,14,28,183,95
|
1425,3116,95,157,1,1066,1293,1336,2622,1481,2297,2018,2058,1773,731,2703,828,829,2094,64,1676,2972,190,2574,1211,379,2212,606,2628,183,1254,3031,0,1821,1082,3065,366,1217,2223,2583,67,585,779,1499,1689,1355,2857,28,2408,2954,723,6,969,2045,387,2047,1511,851,14,1024,320,2372,2197,2958,531,2968,512,1853,1331,1245
|
0.011755338385683791,-4.125938690516134,2.0329969890041335,1.5362117181364128,5.144282894154371,0.22183326505174678,0.0916230653837448,0.06514870608694326,-0.7740586736982547,-0.015166862701093613,-0.4976220214613302,-0.3217563066408477,-0.35062453129738713,-0.17996198897025922,0.47202132781882844,-0.8698275055005745,0.39833990773856,0.39833990773856,-0.37966711166030426,2.401552801979837,-0.12439757025387724,-1.379165978216167,1.4181869234230973,-0.7112482098625537,0.14413493056950505,0.8915034664671595,-0.4382834749199662,0.5923317961811347,-0.7740586736982547,1.4380669400587471,0.11795129526109982,-1.6363177401147757,5.899253810656477,-0.20798764245173287,0.22183326505174678,-1.947658572174278,0.9137480795405156,0.14413493056950505,-0.4382834749199662,-0.7112482098625537,2.385428384194839,0.616030896851247,0.4475879086837396,-0.015166862701093613,-0.12439757025387724,0.06514870608694326,-1.0672234487170145,3.369120265484028,-0.5576999615504026,-1.3081044921965708,0.4963293559988893,4.647892361308431,0.298283282312465,-0.3217563066408477,0.8915034664671595,-0.3217563066408477,-0.015166862701093613,0.39833990773856,4.1208994144256375,0.2729362763877655,1.001687568375461,-0.5275674680675104,-0.4088860728488319,-1.3081044921965708,0.709655477037906,-1.3435062986012638,0.7327741710393836,-0.20798764245173287,0.0916230653837448,0.14413493056950505
| 3,120
|
Thin ribs
| 6
| 14
| 2.494229
| 0.012623
|
P02545,O75431,Q14999,Q32P28,O95831,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,464,430,74,86,123
|
2088,464,123,2806,86,376,1120,1724,1548,430,1653,74,492,1421
|
-0.37966711166030426,0.7786741122076469,1.763620063558507,-1.000530653277979,2.119398055387944,0.8915034664671595,0.19607443889255075,-0.15209923198018688,-0.042241579625993585,0.8241310428665671,-0.09685523182921355,2.3039419144770994,0.75578003326324,0.038526658332115674
| 3,120
|
SH3-like domain superfamily [IPR036028]
| 14
| 35
| 2.49131
| 0.012727
|
O00459,Q13813,Q9NZQ3,Q9UQB8,Q14168,Q9NZW5,P62993,Q12959,O75962,Q5JRA6,Q15642,P46108,Q96PC5,Q14847
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
156,394,202,13,571,578,148,502,273,384,473,125,223,429
|
156,2531,273,605,1776,1256,125,2753,148,922,836,502,394,1046,571,744,961,429,473,384,1008,223,1364,1607,2979,202,578,947,1579,1147,1283,13,1027,854,2600
|
1.5362117181364128,-0.6801459566044995,1.1093425443192109,0.5923317961811347,-0.17996198897025922,0.11795129526109982,1.763620063558507,-0.9347396848564197,1.5748962832288216,0.32349580032456454,0.39833990773856,0.7327741710393836,0.8691530690352253,0.24745340385816628,0.6396116988763457,0.47202132781882844,0.298283282312465,0.8241310428665671,0.7786741122076469,0.8915034664671595,0.2729362763877655,1.2765988138362,0.06514870608694326,-0.0694704733838678,-1.379165978216167,1.3378069158806978,0.6396116988763457,0.32349580032456454,-0.042241579625993585,0.19607443889255075,0.11795129526109982,4.164591374905695,0.2729362763877655,0.39833990773856,-0.7112482098625537
| 3,120
|
Metalloexopeptidase activity
| 6
| 19
| 2.486961
| 0.012884
|
P02786,Q9NZ08,O75976,P55786,O75844,Q9UIQ6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
172,145,177,29,123,31
|
123,177,172,1864,2829,1919,1118,2341,29,285,477,1754,1366,2931,1662,2452,1900,145,31
|
1.763620063558507,1.4578623634759529,1.4775738794299105,-0.23617802356071166,-1.0337628479999912,-0.2645349940023304,0.19607443889255075,-0.5275674680675104,3.3430496340161606,1.0880085580638097,0.7786741122076469,-0.15209923198018688,0.06514870608694326,-1.238060398252917,-0.09685523182921355,-0.5880217491572218,-0.23617802356071166,1.5941183060567525,3.3299572675677735
| 3,120
|
Mitochondrial fusion
| 10
| 16
| 2.484385
| 0.012978
|
Q9Y4W6,O60313,P02786,Q9H6R6,Q9UJZ1,Q9NX63,Q9GZY8,Q96E52,Q99536,O95140
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
345,389,172,143,512,312,510,179,576,332
|
389,332,172,2316,1232,2232,179,576,510,648,143,1758,312,512,345,2500
|
0.8691530690352253,0.9579237536502591,1.4775738794299105,-0.4976220214613302,0.14413493056950505,-0.4382834749199662,1.4578623634759529,0.6396116988763457,0.7327741710393836,0.5685132566383815,1.6132609997025542,-0.15209923198018688,1.023417311456126,0.7327741710393836,0.9579237536502591,-0.6185351182463072
| 3,120
|
Abnormality of the ribs
| 20
| 64
| 2.475488
| 0.013305
|
P02545,Q8TAA9,Q9UHX1,P54802,P16278,Q7RTS9,Q96L58,P39019,Q14999,Q32P28,O95831,O60826,Q6DKJ4,O75431,Q15427,Q9H0W5,O96028,O75718,P15586,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,131,397,264,283,32,166,425,430,74,86,331,220,464,490,492,347,346,111,123
|
2454,2088,2331,331,2014,464,2970,346,123,2806,909,86,347,1070,376,1632,111,283,1209,1635,1389,2573,2254,1638,708,425,3059,1120,1724,264,1930,2106,1786,1548,1219,2583,1942,746,430,490,1687,1653,74,2268,1455,220,2664,2072,32,2073,131,2642,528,166,1463,2888,492,2597,397,1194,1421,1374,2086,1028
|
-0.6185351182463072,-0.37966711166030426,-0.5275674680675104,0.9579237536502591,-0.3217563066408477,0.7786741122076469,-1.379165978216167,0.9358878616746352,1.763620063558507,-1.000530653277979,0.32349580032456454,2.119398055387944,0.9358878616746352,0.22183326505174678,0.8915034664671595,-0.09685523182921355,1.8370056925799199,1.0880085580638097,0.14413493056950505,-0.09685523182921355,0.038526658332115674,-0.7112482098625537,-0.46786141367036915,-0.09685523182921355,0.4963293559988893,0.8241310428665671,-1.9076504275094626,0.19607443889255075,-0.15209923198018688,1.1305797371850148,-0.2645349940023304,-0.37966711166030426,-0.17996198897025922,-0.042241579625993585,0.14413493056950505,-0.7112482098625537,-0.2645349940023304,0.47202132781882844,0.8241310428665671,0.75578003326324,-0.12439757025387724,-0.09685523182921355,2.3039419144770994,-0.46786141367036915,0.011755338385683791,1.2765988138362,-0.8057719361207141,-0.35062453129738713,3.210375491197299,-0.35062453129738713,1.7078061122023387,-0.7740586736982547,0.709655477037906,1.516747891198495,0.011755338385683791,-1.1348420125464262,0.75578003326324,-0.7112482098625537,0.8691530690352253,0.17017548246536693,0.038526658332115674,0.06514870608694326,-0.35062453129738713,0.2729362763877655
| 3,120
|
F-type and V-type ATPases
| 6
| 15
| 2.473873
| 0.013366
|
Q93050,O75947,Q9Y487,P00846,P36542,P24539
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
99,252,150,52,305,94
|
252,52,422,1389,859,94,919,305,1645,2849,883,2163,99,1763,150
|
1.1517209730784248,2.7276227820437797,0.8241310428665671,0.038526658332115674,0.37352278495630703,2.050407604865225,0.32349580032456454,1.023417311456126,-0.09685523182921355,-1.0672234487170145,0.3485751885508132,-0.4088860728488319,1.9979768307458792,-0.15209923198018688,1.5748962832288216
| 3,120
|
Limb ataxia
| 7
| 27
| 2.473041
| 0.013397
|
O14773,Q14108,P07196,Q8IV08,Q10713,P41440,O75298
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,67,103,39,105,73,110
|
2774,66,1199,110,1773,2937,103,2675,3058,1210,2387,2948,73,1215,105,382,67,39,2641,900,1755,1611,126,852,622,1667,345
|
-0.9675239012000673,2.385428384194839,0.14413493056950505,1.8551713497297029,-0.17996198897025922,-1.2729570159514279,1.9271271193823978,-0.8376939983695894,-1.86796338467221,0.14413493056950505,-0.5576999615504026,-1.3081044921965708,2.3039419144770994,0.14413493056950505,1.9092431533941194,0.8915034664671595,2.385428384194839,3.0875268139564396,-0.7740586736982547,0.3485751885508132,-0.15209923198018688,-0.0694704733838678,1.763620063558507,0.39833990773856,0.5923317961811347,-0.09685523182921355,0.9579237536502591
| 3,120
|
Peptide binding
| 13
| 64
| 2.445817
| 0.014452
|
Q15392,O14773,P42892,O00264,P10321,Q9NZ08,P24390,Q9BYT8,O00629,O15212,Q8WTV0,P55786,Q9UIQ6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
130,66,43,262,240,145,116,245,146,212,28,29,31
|
262,1521,2205,146,66,212,2748,1629,1154,1071,1816,655,1714,240,2096,2894,1638,116,1974,2677,3026,2538,658,834,1719,1035,43,2435,1163,1257,1258,455,2027,1165,29,1930,2633,884,2475,1937,2687,685,1651,409,294,130,589,2184,28,1361,2713,816,3021,1019,245,1056,620,1279,2767,145,2007,532,31,2842
|
1.1305797371850148,-0.042241579625993585,-0.4382834749199662,1.5748962832288216,2.385428384194839,1.297090899466863,-0.9347396848564197,-0.09685523182921355,0.17017548246536693,0.22183326505174678,-0.20798764245173287,0.5445741216866079,-0.15209923198018688,1.2145771446757452,-0.37966711166030426,-1.169006197935009,-0.09685523182921355,1.8004585753415925,-0.29306044672954845,-0.8376939983695894,-1.5987473131497758,-0.6801459566044995,0.5445741216866079,0.39833990773856,-0.15209923198018688,0.24745340385816628,2.875037373385399,-0.5880217491572218,0.17017548246536693,0.11795129526109982,0.11795129526109982,0.8014574420423553,-0.3217563066408477,0.17017548246536693,3.3430496340161606,-0.2645349940023304,-0.7740586736982547,0.3485751885508132,-0.6185351182463072,-0.2645349940023304,-0.8376939983695894,0.5205132181705904,-0.09685523182921355,0.8466959209611702,1.0665769311873845,1.7078061122023387,0.616030896851247,-0.4088860728488319,3.369120265484028,0.06514870608694326,-0.8698275055005745,0.42302785571210444,-1.561461734297637,0.2729362763877655,1.193718866633161,0.24745340385816628,0.5923317961811347,0.11795129526109982,-0.9347396848564197,1.5941183060567525,-0.29306044672954845,0.709655477037906,3.3299572675677735,-1.0337628479999912
| 3,120
|
Organelle fusion
| 25
| 52
| 2.445113
| 0.014481
|
Q9UQN3,O95249,O60313,Q9H6R6,O43752,O60763,P02786,Q9NX63,Q96E52,Q99536,Q9BSR8,P31751,O95721,Q15075,Q9Y3E7,Q9Y4W6,O60499,O95140,O15400,Q12981,O95295,Q9UJZ1,P04083,Q9GZY8,Q9H300
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
132,253,389,143,766,767,172,312,179,576,848,183,69,324,203,345,448,332,218,611,730,512,731,510,648
|
1857,2564,218,766,389,2143,448,767,1380,332,253,730,69,172,731,1298,828,1634,183,2064,3055,2217,1984,1169,611,1941,324,2316,1355,1095,1232,2232,179,576,848,1368,510,2920,648,143,1758,1024,312,2415,1665,512,1853,2008,132,203,345,2500
|
-0.23617802356071166,-0.7112482098625537,1.2765988138362,0.4475879086837396,0.8691530690352253,-0.4088860728488319,0.8014574420423553,0.4475879086837396,0.038526658332115674,0.9579237536502591,1.1517209730784248,0.47202132781882844,2.3692468623114746,1.4775738794299105,0.47202132781882844,0.0916230653837448,0.39833990773856,-0.09685523182921355,1.4380669400587471,-0.35062453129738713,-1.8285925507530927,-0.4382834749199662,-0.29306044672954845,0.17017548246536693,0.5923317961811347,-0.2645349940023304,0.979856683830239,-0.4976220214613302,0.06514870608694326,0.22183326505174678,0.14413493056950505,-0.4382834749199662,1.4578623634759529,0.6396116988763457,0.39833990773856,0.06514870608694326,0.7327741710393836,-1.2034112370325538,0.5685132566383815,1.6132609997025542,-0.15209923198018688,0.2729362763877655,1.023417311456126,-0.5576999615504026,-0.09685523182921355,0.7327741710393836,-0.20798764245173287,-0.29306044672954845,1.7078061122023387,1.3378069158806978,0.9579237536502591,-0.6185351182463072
| 3,120
|
Golgi membrane
| 25
| 133
| 2.44006
| 0.014685
|
Q15392,O95249,Q7LGA3,Q8IZA0,P53367,Q8NCH0,O60476,O15260,Q9Y282,O43505,Q8NBN3,Q96L58,Q8IV08,Q5BJH7,Q14108,O95721,Q9P2W9,Q10471,Q10713,Q8N4V1,P11717,P10321,P24390,Q92896,Q96JB2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
130,253,19,279,284,161,158,157,33,34,35,166,39,318,67,69,92,351,105,250,233,240,116,118,122
|
2802,1621,3072,2564,905,2378,157,2379,34,1290,2089,766,158,448,767,1380,1672,879,253,730,69,1154,1071,1634,2023,240,1676,233,880,2574,116,3010,1874,567,1159,1644,2514,2466,1304,1821,1397,994,1724,862,1876,455,284,2396,2866,1123,2517,1984,1729,1823,1086,1167,2106,2165,366,1825,2108,1126,863,351,471,1401,105,1220,1734,1043,1941,1090,67,776,1047,2117,636,130,1554,1740,1597,318,929,19,2316,1355,783,39,279,250,1314,35,161,868,2075,542,1888,2076,118,1185,3099,122,166,1319,755,558,2045,756,2236,902,790,942,1104,620,2049,793,671,2132,2957,2197,92,1961,2562,1579,1852,1194,33,2135,2243,1027,2700,1707,1520
|
-1.000530653277979,-0.09685523182921355,-2.1110040441905302,-0.7112482098625537,0.32349580032456454,-0.5576999615504026,1.5362117181364128,-0.5576999615504026,3.1697972893617217,0.0916230653837448,-0.37966711166030426,0.4475879086837396,1.5362117181364128,0.8014574420423553,0.4475879086837396,0.038526658332115674,-0.12439757025387724,0.3485751885508132,1.1517209730784248,0.47202132781882844,2.3692468623114746,0.17017548246536693,0.22183326505174678,-0.09685523182921355,-0.3217563066408477,1.2145771446757452,-0.12439757025387724,1.2353427068536198,0.3485751885508132,-0.7112482098625537,1.8004585753415925,-1.5244569016571512,-0.23617802356071166,0.6396116988763457,0.17017548246536693,-0.09685523182921355,-0.6492423972397605,-0.6185351182463072,0.0916230653837448,-0.20798764245173287,0.038526658332115674,0.2729362763877655,-0.15209923198018688,0.37352278495630703,-0.23617802356071166,0.8014574420423553,1.0880085580638097,-0.5576999615504026,-1.1009154766800557,0.19607443889255075,-0.6492423972397605,-0.29306044672954845,-0.15209923198018688,-0.20798764245173287,0.22183326505174678,0.17017548246536693,-0.37966711166030426,-0.4088860728488319,0.9137480795405156,-0.20798764245173287,-0.37966711166030426,0.19607443889255075,0.37352278495630703,0.9358878616746352,0.7786741122076469,0.038526658332115674,1.9092431533941194,0.14413493056950505,-0.15209923198018688,0.24745340385816628,-0.2645349940023304,0.22183326505174678,2.385428384194839,0.4475879086837396,0.24745340385816628,-0.37966711166030426,0.5685132566383815,1.7078061122023387,-0.042241579625993585,-0.15209923198018688,-0.0694704733838678,1.001687568375461,0.32349580032456454,3.9302356800799503,-0.4976220214613302,0.06514870608694326,0.4475879086837396,3.0875268139564396,1.1093425443192109,1.172767077784285,0.0916230653837448,3.156189494592303,1.5362117181364128,0.37352278495630703,-0.35062453129738713,0.6864228881683501,-0.23617802356071166,-0.35062453129738713,1.8004585753415925,0.17017548246536693,-2.8239170804910954,1.7820760211495976,1.516747891198495,0.0916230653837448,0.47202132781882844,0.6630753264781283,-0.3217563066408477,0.47202132781882844,-0.4382834749199662,0.3485751885508132,0.4475879086837396,0.32349580032456454,0.22183326505174678,0.5923317961811347,-0.3217563066408477,0.4475879086837396,0.5445741216866079,-0.37966711166030426,-1.3081044921965708,-0.4088860728488319,2.0677525498216016,-0.2645349940023304,-0.6801459566044995,-0.042241579625993585,-0.20798764245173287,0.17017548246536693,3.1833640634904,-0.37966711166030426,-0.4382834749199662,0.2729362763877655,-0.8376939983695894,-0.12439757025387724,-0.015166862701093613
| 3,120
|
Late endosome
| 14
| 64
| 2.432748
| 0.014985
|
O15400,Q14108,Q9UQN3,Q8IV08,Q9Y4G8,Q9Y3E7,P11717,P20645,Q9H9H4,O95772,Q8IZ07,Q9BXB4,Q9HD42,O15118
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
218,67,132,39,168,203,233,46,311,50,369,387,260,95
|
2564,1376,95,218,765,1336,50,828,1482,807,1156,2149,233,1484,2150,46,831,2155,1159,2389,2339,2064,1876,2217,1086,1932,2916,1219,382,67,2549,1048,1996,1499,39,1097,369,2486,478,693,1237,2126,723,941,1272,2492,788,387,2128,2920,2192,311,260,1024,2372,1413,2415,3028,1853,2008,132,1616,203,168
|
-0.7112482098625537,0.038526658332115674,2.0329969890041335,1.2765988138362,0.4475879086837396,0.06514870608694326,2.7723526302969184,0.39833990773856,-0.015166862701093613,0.42302785571210444,0.17017548246536693,-0.4088860728488319,1.2353427068536198,-0.015166862701093613,-0.4088860728488319,2.831314292458711,0.39833990773856,-0.4088860728488319,0.17017548246536693,-0.5576999615504026,-0.5275674680675104,-0.35062453129738713,-0.23617802356071166,-0.4382834749199662,0.22183326505174678,-0.2645349940023304,-1.2034112370325538,0.14413493056950505,0.8915034664671595,2.385428384194839,-0.6801459566044995,0.24745340385816628,-0.29306044672954845,-0.015166862701093613,3.0875268139564396,0.22183326505174678,0.9137480795405156,-0.6185351182463072,0.7786741122076469,0.5205132181705904,0.14413493056950505,-0.37966711166030426,0.4963293559988893,0.32349580032456454,0.11795129526109982,-0.6185351182463072,0.4475879086837396,0.8915034664671595,-0.37966711166030426,-1.2034112370325538,-0.4088860728488319,1.023417311456126,1.1517209730784248,0.2729362763877655,-0.5275674680675104,0.038526658332115674,-0.5576999615504026,-1.5987473131497758,-0.20798764245173287,-0.29306044672954845,1.7078061122023387,-0.0694704733838678,1.3378069158806978,1.516747891198495
| 3,120
|
Horizontal nystagmus
| 9
| 22
| 2.428423
| 0.015165
|
O14773,Q9H061,P20700,Q9NSE4,O60313,P00846,P52815,O95831,P37198
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,619,288,344,389,52,333,86,568
|
1859,1197,66,1199,389,677,86,52,1773,288,568,333,2030,2162,1175,1563,1838,619,344,852,2372,1667
|
-0.23617802356071166,0.14413493056950505,2.385428384194839,0.14413493056950505,0.8691530690352253,0.5205132181705904,2.119398055387944,2.7276227820437797,-0.17996198897025922,1.0665769311873845,0.6396116988763457,0.9579237536502591,-0.3217563066408477,-0.4088860728488319,0.17017548246536693,-0.042241579625993585,-0.20798764245173287,0.5923317961811347,0.9579237536502591,0.39833990773856,-0.5275674680675104,-0.09685523182921355
| 3,120
|
Glycerophospholipid metabolic process
| 7
| 54
| 2.422437
| 0.015417
|
P35790,Q9NPH0,Q9NX62,Q10713,Q8NCC3,Q9BVG9,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,5,137,105,21,85,28
|
2671,2501,156,2924,1377,1769,1481,2297,2623,2018,2302,605,2256,0,2338,2847,3004,3059,1121,1786,105,1455,1688,2178,1883,1796,1050,2358,1837,21,868,894,28,1838,1183,1235,506,668,669,341,259,2819,2188,85,1804,2047,5,2132,3000,137,2957,1242,2199,512
|
-0.8376939983695894,-0.6492423972397605,1.5362117181364128,-1.238060398252917,0.038526658332115674,-0.17996198897025922,-0.015166862701093613,-0.4976220214613302,-0.7740586736982547,-0.3217563066408477,-0.4976220214613302,0.5923317961811347,-0.46786141367036915,5.899253810656477,-0.5275674680675104,-1.0672234487170145,-1.4877287999834443,-1.9076504275094626,0.19607443889255075,-0.17996198897025922,1.9092431533941194,0.011755338385683791,-0.12439757025387724,-0.4088860728488319,-0.23617802356071166,-0.17996198897025922,0.24745340385816628,-0.5275674680675104,-0.20798764245173287,3.7786917531689994,0.37352278495630703,0.3485751885508132,3.369120265484028,-0.20798764245173287,0.17017548246536693,0.14413493056950505,0.7327741710393836,0.5445741216866079,0.5445741216866079,0.9579237536502591,1.1517209730784248,-1.000530653277979,-0.4088860728488319,2.153508561251972,-0.17996198897025922,-0.3217563066408477,4.657618122456405,-0.37966711166030426,-1.451273498282404,1.651310887354022,-1.3081044921965708,0.14413493056950505,-0.4088860728488319,0.7327741710393836
| 3,120
|
Retinal degeneration
| 11
| 54
| 2.42093
| 0.015481
|
P02545,O14773,Q96F07,Q10713,P51648,Q13510,O60313,Q96PZ0,Q7LGA3,P50897,O75503
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,66,325,105,91,44,389,371,19,51,27
|
2601,66,1623,389,951,27,1383,421,1480,2570,376,1773,1071,1914,1917,2460,2253,2337,2512,1642,1645,2339,1781,2437,51,91,2609,808,569,2311,1933,2634,105,44,1788,2611,19,2316,1050,784,1886,2988,814,2078,325,371,1893,1611,1512,671,2193,852,2199,1667
|
-0.7425516146318213,2.385428384194839,-0.09685523182921355,0.8691530690352253,0.298283282312465,3.44643436310832,0.038526658332115674,0.8241310428665671,-0.015166862701093613,-0.7112482098625537,0.8915034664671595,-0.17996198897025922,0.22183326505174678,-0.2645349940023304,-0.2645349940023304,-0.6185351182463072,-0.46786141367036915,-0.5275674680675104,-0.6492423972397605,-0.09685523182921355,-0.09685523182921355,-0.5275674680675104,-0.17996198897025922,-0.5880217491572218,2.757491625277111,2.0677525498216016,-0.7425516146318213,0.42302785571210444,0.6396116988763457,-0.4976220214613302,-0.2645349940023304,-0.7740586736982547,1.9092431533941194,2.860509873296997,-0.17996198897025922,-0.7425516146318213,3.9302356800799503,-0.4976220214613302,0.24745340385816628,0.4475879086837396,-0.23617802356071166,-1.4150871474875513,0.42302785571210444,-0.35062453129738713,0.979856683830239,0.9137480795405156,-0.23617802356071166,-0.0694704733838678,-0.015166862701093613,0.5445741216866079,-0.4088860728488319,0.39833990773856,-0.4088860728488319,-0.09685523182921355
| 3,120
|
Slowly progressive
| 15
| 58
| 2.402137
| 0.0163
|
P04792,P02545,O14773,Q99720,P50402,Q8IV08,P07196,P41440,Q9Y4W6,Q9P0J0,O95831,O14979,Q9NR77,O95140,Q92734
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,376,66,6,289,39,103,73,345,313,86,272,126,332,386
|
1197,534,66,272,1199,981,856,768,677,332,86,376,128,1249,103,2808,3058,2537,1871,990,2948,1487,73,2680,956,289,1724,608,1121,2030,1785,1219,1733,714,2548,1992,2868,1000,2227,432,1558,1175,1457,39,2358,2641,386,1800,3051,6,1054,126,2327,313,2134,1110,345,533
|
0.14413493056950505,0.6864228881683501,2.385428384194839,1.1093425443192109,0.14413493056950505,0.2729362763877655,0.37352278495630703,0.4475879086837396,0.5205132181705904,0.9579237536502591,2.119398055387944,0.8915034664671595,1.7264856813353782,0.11795129526109982,1.9271271193823978,-1.000530653277979,-1.86796338467221,-0.6801459566044995,-0.23617802356071166,0.2729362763877655,-1.3081044921965708,-0.015166862701093613,2.3039419144770994,-0.8376939983695894,0.298283282312465,1.0665769311873845,-0.15209923198018688,0.5923317961811347,0.19607443889255075,-0.3217563066408477,-0.17996198897025922,0.14413493056950505,-0.15209923198018688,0.4963293559988893,-0.6801459566044995,-0.29306044672954845,-1.1009154766800557,0.2729362763877655,-0.4382834749199662,0.8241310428665671,-0.042241579625993585,0.17017548246536693,0.011755338385683791,3.0875268139564396,-0.5275674680675104,-0.7740586736982547,0.8915034664671595,-0.17996198897025922,-1.7895331421785752,4.647892361308431,0.24745340385816628,1.763620063558507,-0.4976220214613302,1.023417311456126,-0.37966711166030426,0.22183326505174678,0.9579237536502591,0.709655477037906
| 3,120
|
Nuclear inner membrane
| 9
| 22
| 2.395515
| 0.016597
|
Q03252,Q99720,P50402,P20700,P62995,Q9UH99,Q13185,O75844,Q8NC56
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
255,6,289,288,265,210,334,123,287
|
123,1294,288,1161,861,289,3074,265,255,334,1350,746,432,2520,1835,287,2408,6,1054,1190,210,763
|
1.763620063558507,0.0916230653837448,1.0665769311873845,0.17017548246536693,0.37352278495630703,1.0665769311873845,-2.1110040441905302,1.1305797371850148,1.1517209730784248,0.9579237536502591,0.06514870608694326,0.47202132781882844,0.8241310428665671,-0.6492423972397605,-0.20798764245173287,1.0880085580638097,-0.5576999615504026,4.647892361308431,0.24745340385816628,0.17017548246536693,1.3174933512024687,0.47202132781882844
| 3,120
|
Abnormality of the wrist
| 8
| 30
| 2.394419
| 0.016647
|
Q7RTS9,Q6DKJ4,Q96L58,Q9H6K4,Q13510,O95831,P16278,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,220,166,174,44,86,283,123
|
2601,2331,982,2673,2014,123,677,86,376,283,1209,2573,708,1302,1121,2030,1786,1219,44,1738,220,32,1185,166,2888,174,2241,2595,1421,2086
|
-0.7425516146318213,-0.5275674680675104,0.2729362763877655,-0.8376939983695894,-0.3217563066408477,1.763620063558507,0.5205132181705904,2.119398055387944,0.8915034664671595,1.0880085580638097,0.14413493056950505,-0.7112482098625537,0.4963293559988893,0.0916230653837448,0.19607443889255075,-0.3217563066408477,-0.17996198897025922,0.14413493056950505,2.860509873296997,-0.15209923198018688,1.2765988138362,3.210375491197299,0.17017548246536693,1.516747891198495,-1.1348420125464262,1.4775738794299105,-0.4382834749199662,-0.7112482098625537,0.038526658332115674,-0.35062453129738713
| 3,120
|
Golgi cisterna
| 7
| 22
| 2.362184
| 0.018168
|
Q8NBN3,O95249,Q96L58,Q10471,Q10713,Q96JB2,Q10472
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
35,253,166,351,105,122,471
|
253,1071,2023,862,2108,1126,863,351,471,105,1220,2117,636,1740,35,542,1888,122,166,1368,1104,1852
|
1.1517209730784248,0.22183326505174678,-0.3217563066408477,0.37352278495630703,-0.37966711166030426,0.19607443889255075,0.37352278495630703,0.9358878616746352,0.7786741122076469,1.9092431533941194,0.14413493056950505,-0.37966711166030426,0.5685132566383815,-0.15209923198018688,3.156189494592303,0.6864228881683501,-0.23617802356071166,1.7820760211495976,1.516747891198495,0.06514870608694326,0.22183326505174678,-0.20798764245173287
| 3,120
|
Protein localization to mitochondrion
| 12
| 60
| 2.361331
| 0.018209
|
Q15388,Q8N4H5,Q15070,Q10713,O14925,Q9P0J0,O60830,O14737,O95831,Q9NS69,Q5JRX3,P55786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
294,70,104,105,171,313,176,211,86,261,307,29
|
2291,2203,1859,1197,211,171,1379,1030,176,1335,1814,1629,332,1909,86,1631,1436,1715,1073,1917,2386,2257,2628,1872,1779,1397,2576,862,1680,29,1493,105,104,294,1792,841,586,307,2316,70,2232,1051,1365,1101,1369,510,648,972,261,2718,313,2416,1764,1476,1027,1110,702,2719,3090,2500
|
-0.4976220214613302,-0.4382834749199662,-0.23617802356071166,0.14413493056950505,1.297090899466863,1.4775738794299105,0.038526658332115674,0.24745340385816628,1.4578623634759529,0.06514870608694326,-0.20798764245173287,-0.09685523182921355,0.9579237536502591,-0.2645349940023304,2.119398055387944,-0.09685523182921355,0.011755338385683791,-0.15209923198018688,0.22183326505174678,-0.2645349940023304,-0.5576999615504026,-0.46786141367036915,-0.7740586736982547,-0.23617802356071166,-0.17996198897025922,0.038526658332115674,-0.7112482098625537,0.37352278495630703,-0.12439757025387724,3.3430496340161606,-0.015166862701093613,1.9092431533941194,1.9271271193823978,1.0665769311873845,-0.17996198897025922,0.39833990773856,0.616030896851247,1.023417311456126,-0.4976220214613302,2.3692468623114746,-0.4382834749199662,0.24745340385816628,0.06514870608694326,0.22183326505174678,0.06514870608694326,0.7327741710393836,0.5685132566383815,0.298283282312465,1.1517209730784248,-0.8698275055005745,1.023417311456126,-0.5576999615504026,-0.15209923198018688,0.011755338385683791,0.2729362763877655,0.22183326505174678,0.5205132181705904,-0.8698275055005745,-2.499432291736275,-0.6185351182463072
| 3,120
|
Glycerolipid metabolic process
| 8
| 63
| 2.358732
| 0.018338
|
P35790,Q9UBV2,Q9NPH0,Q9NX62,Q10713,Q8NCC3,Q9BVG9,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,68,5,137,105,21,85,28
|
2671,2501,156,2924,1377,1769,2507,1481,2297,2623,2018,2302,605,2256,1254,0,2338,2847,3004,3059,1082,1121,1786,2583,105,1945,586,1455,1688,2178,1883,1796,1050,2358,1837,21,557,868,894,28,1838,1183,1235,506,2408,668,669,341,259,2819,2188,85,1804,2047,5,2132,3000,137,2957,1242,68,2199,512
|
-0.8376939983695894,-0.6492423972397605,1.5362117181364128,-1.238060398252917,0.038526658332115674,-0.17996198897025922,-0.6492423972397605,-0.015166862701093613,-0.4976220214613302,-0.7740586736982547,-0.3217563066408477,-0.4976220214613302,0.5923317961811347,-0.46786141367036915,0.11795129526109982,5.899253810656477,-0.5275674680675104,-1.0672234487170145,-1.4877287999834443,-1.9076504275094626,0.22183326505174678,0.19607443889255075,-0.17996198897025922,-0.7112482098625537,1.9092431533941194,-0.2645349940023304,0.616030896851247,0.011755338385683791,-0.12439757025387724,-0.4088860728488319,-0.23617802356071166,-0.17996198897025922,0.24745340385816628,-0.5275674680675104,-0.20798764245173287,3.7786917531689994,0.6630753264781283,0.37352278495630703,0.3485751885508132,3.369120265484028,-0.20798764245173287,0.17017548246536693,0.14413493056950505,0.7327741710393836,-0.5576999615504026,0.5445741216866079,0.5445741216866079,0.9579237536502591,1.1517209730784248,-1.000530653277979,-0.4088860728488319,2.153508561251972,-0.17996198897025922,-0.3217563066408477,4.657618122456405,-0.37966711166030426,-1.451273498282404,1.651310887354022,-1.3081044921965708,0.14413493056950505,2.385428384194839,-0.4088860728488319,0.7327741710393836
| 3,120
|
EF-hand domain pair [IPR011992]
| 17
| 48
| 2.358691
| 0.01834
|
Q13813,Q96AY3,Q9BPX6,O43852,Q9H8M7,Q99653,Q9UJS0,Q9UPN3,P80303,Q9UBV8,Q9H223,Q99584,P46939,Q14257,Q15293,Q02818,Q03001
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
394,436,595,134,559,558,602,373,15,314,511,244,584,87,249,30,500
|
981,134,856,1587,909,2675,733,2893,1300,2302,605,2100,1922,1119,1343,1162,584,2783,3032,15,30,500,394,87,2585,249,1174,1308,812,1797,750,1358,868,436,1186,939,244,558,595,1272,511,851,559,1192,2797,314,602,373
|
0.2729362763877655,1.6702193073777245,0.37352278495630703,-0.0694704733838678,0.32349580032456454,-0.8376939983695894,0.47202132781882844,-1.169006197935009,0.0916230653837448,-0.4976220214613302,0.5923317961811347,-0.37966711166030426,-0.2645349940023304,0.19607443889255075,0.06514870608694326,0.17017548246536693,0.616030896851247,-0.9675239012000673,-1.6363177401147757,4.05454044544889,3.3299572675677735,0.7327741710393836,0.8691530690352253,2.119398055387944,-0.7112482098625537,1.172767077784285,0.17017548246536693,0.0916230653837448,0.42302785571210444,-0.17996198897025922,0.47202132781882844,0.06514870608694326,0.37352278495630703,0.8241310428665671,0.17017548246536693,0.32349580032456454,1.193718866633161,0.6630753264781283,0.616030896851247,0.11795129526109982,0.7327741710393836,0.39833990773856,0.6630753264781283,0.17017548246536693,-0.9675239012000673,1.023417311456126,0.616030896851247,0.9137480795405156
| 3,120
|
Receptor
| 7
| 27
| 2.353722
| 0.018587
|
Q14108,Q567V2,Q9UQB8,P20645,A6NIH7,Q9NR77,Q8WTV0
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
67,38,13,46,77,126,28
|
77,2803,2089,1906,768,1204,2333,911,233,46,1591,405,502,775,67,2661,3019,38,28,1950,2492,2743,442,126,2006,3086,13
|
2.2209781437623697,-1.000530653277979,-0.37966711166030426,-0.2645349940023304,0.4475879086837396,0.14413493056950505,-0.5275674680675104,0.32349580032456454,1.2353427068536198,2.831314292458711,-0.0694704733838678,0.8466959209611702,0.7327741710393836,0.4475879086837396,2.385428384194839,-0.8057719361207141,-1.561461734297637,3.101343321075666,3.369120265484028,-0.2645349940023304,-0.6185351182463072,-0.902175152364751,0.8241310428665671,1.763620063558507,-0.29306044672954845,-2.41046038039257,4.164591374905695
| 3,120
|
Predicted secreted proteins
| 13
| 51
| 2.350865
| 0.01873
|
Q9UM22,Q9UMX5,Q08380,O60888,P02786,P80303,P84157,Q9NZ08,Q15165,Q99584,Q9HB40,Q02818,Q8N128
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
65,4,75,109,172,15,277,145,112,244,24,30,191
|
534,1334,627,109,346,1067,3030,172,731,1969,828,2947,1483,2972,2096,771,1638,1537,2024,632,1783,2866,3100,3065,1125,15,3105,277,30,408,75,1042,1222,1045,112,191,2857,2591,936,3066,244,1273,309,2045,2931,671,24,145,65,4,1286
|
0.6864228881683501,0.06514870608694326,0.5685132566383815,1.8551713497297029,0.9358878616746352,0.22183326505174678,-1.6363177401147757,1.4775738794299105,0.47202132781882844,-0.29306044672954845,0.39833990773856,-1.3081044921965708,-0.015166862701093613,-1.379165978216167,-0.37966711166030426,0.4475879086837396,-0.09685523182921355,-0.042241579625993585,-0.3217563066408477,0.5685132566383815,-0.17996198897025922,-1.1009154766800557,-2.8720339730904962,-1.947658572174278,0.19607443889255075,4.05454044544889,-3.3802800898113703,1.1093425443192109,3.3299572675677735,0.8466959209611702,2.2709365393861507,0.24745340385816628,0.14413493056950505,0.24745340385816628,1.8370056925799199,1.3982216195028532,-1.0672234487170145,-0.7112482098625537,0.32349580032456454,-1.947658572174278,1.193718866633161,0.11795129526109982,1.023417311456126,-0.3217563066408477,-1.238060398252917,0.5445741216866079,3.706966810655375,1.5941183060567525,2.401552801979837,4.753702876862137,0.11795129526109982
| 3,120
|
Impaired vibratory sensation
| 7
| 29
| 2.34963
| 0.018792
|
O14773,P07196,P20700,O75298,O43819,P00846,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,103,288,110,239,52,126
|
2291,66,2088,1199,239,110,677,332,52,103,1715,1917,288,1487,1215,2030,2398,2758,1548,1000,1457,813,2641,1838,2794,1606,900,126,533
|
-0.4976220214613302,2.385428384194839,-0.37966711166030426,0.14413493056950505,1.2145771446757452,1.8551713497297029,0.5205132181705904,0.9579237536502591,2.7276227820437797,1.9271271193823978,-0.15209923198018688,-0.2645349940023304,1.0665769311873845,-0.015166862701093613,0.14413493056950505,-0.3217563066408477,-0.5576999615504026,-0.9347396848564197,-0.042241579625993585,0.2729362763877655,0.011755338385683791,0.42302785571210444,-0.7740586736982547,-0.20798764245173287,-0.9675239012000673,-0.0694704733838678,0.3485751885508132,1.763620063558507,0.709655477037906
| 3,120
|
Abnormality of the calf
| 16
| 58
| 2.337817
| 0.019397
|
Q7RTS9,O75431,Q96L58,Q15056,Q15427,Q9NX62,Q32P28,Q9NWH9,Q9NSE4,O75718,P08236,Q7LGA3,Q13126,O95831,P16278,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,464,166,323,490,137,74,443,344,346,247,19,20,86,283,126
|
2204,2423,2013,2014,464,346,1712,86,2018,2093,247,2829,283,1209,1916,2573,2938,2337,2433,2388,2389,1302,1875,1120,998,684,1786,2916,1219,924,20,1738,323,490,1263,74,19,32,2523,813,2073,2642,528,166,2000,2888,2412,2241,126,344,2595,443,137,2669,1371,2134,1286,2086
|
-0.4382834749199662,-0.5880217491572218,-0.3217563066408477,-0.3217563066408477,0.7786741122076469,0.9358878616746352,-0.15209923198018688,2.119398055387944,-0.3217563066408477,-0.37966711166030426,1.172767077784285,-1.0337628479999912,1.0880085580638097,0.14413493056950505,-0.2645349940023304,-0.7112482098625537,-1.2729570159514279,-0.5275674680675104,-0.5880217491572218,-0.5576999615504026,-0.5576999615504026,0.0916230653837448,-0.23617802356071166,0.19607443889255075,0.2729362763877655,0.5205132181705904,-0.17996198897025922,-1.2034112370325538,0.14413493056950505,0.32349580032456454,3.7786917531689994,-0.15209923198018688,0.979856683830239,0.75578003326324,0.11795129526109982,2.3039419144770994,3.9302356800799503,3.210375491197299,-0.6492423972397605,0.42302785571210444,-0.35062453129738713,-0.7740586736982547,0.709655477037906,1.516747891198495,-0.29306044672954845,-1.1348420125464262,-0.5576999615504026,-0.4382834749199662,1.763620063558507,0.9579237536502591,-0.7112482098625537,0.8241310428665671,1.651310887354022,-0.8057719361207141,0.06514870608694326,-0.37966711166030426,0.11795129526109982,-0.35062453129738713
| 3,120
|
Organic acid transport
| 18
| 44
| 2.3331
| 0.019643
|
Q9H9B4,O43772,P08183,Q9H2H9,Q9UBX3,P41440,Q9UJS0,P29375,P04083,O95563,Q9BQT8,Q96NB2,O14908,Q8TDW0,P30825,Q9H2D1,P31751,P23786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
820,1,64,758,797,73,602,606,731,550,480,575,579,189,63,61,183,379
|
1149,579,1,1066,1967,1587,1628,550,1481,2058,731,911,2094,64,912,1676,2972,2938,379,2212,606,63,183,1254,73,1082,2706,2397,808,1594,2444,2690,1224,1689,1882,189,575,480,61,758,1661,820,797,602
|
0.17017548246536693,0.616030896851247,5.144282894154371,0.22183326505174678,-0.29306044672954845,-0.0694704733838678,-0.09685523182921355,0.6630753264781283,-0.015166862701093613,-0.35062453129738713,0.47202132781882844,0.32349580032456454,-0.37966711166030426,2.401552801979837,0.32349580032456454,-0.12439757025387724,-1.379165978216167,-1.2729570159514279,0.8915034664671595,-0.4382834749199662,0.5923317961811347,2.449587253406975,1.4380669400587471,0.11795129526109982,2.3039419144770994,0.22183326505174678,-0.8698275055005745,-0.5576999615504026,0.42302785571210444,-0.0694704733838678,-0.5880217491572218,-0.8376939983695894,0.14413493056950505,-0.12439757025387724,-0.23617802356071166,1.4380669400587471,0.6396116988763457,0.7786741122076469,2.4813316430188412,0.47202132781882844,-0.09685523182921355,0.42302785571210444,0.4475879086837396,0.616030896851247
| 3,120
|
EF-Hand 1, calcium-binding site [IPR018247]
| 12
| 35
| 2.329936
| 0.01981
|
Q13813,Q96AY3,Q9BPX6,O43852,Q9UPN3,P80303,Q9UBV8,Q9H223,Q14257,Q15293,Q02818,Q03001
|
Sequence
|
InterPro Binding site
|
interpro_binding_site
|
394,436,595,134,373,15,314,511,87,249,30,500
|
981,134,856,1587,909,2675,733,2893,1300,2302,605,2100,1922,1119,1343,1162,15,30,500,394,87,2585,249,1308,1797,436,939,595,1272,511,851,1192,2797,314,373
|
0.2729362763877655,1.6702193073777245,0.37352278495630703,-0.0694704733838678,0.32349580032456454,-0.8376939983695894,0.47202132781882844,-1.169006197935009,0.0916230653837448,-0.4976220214613302,0.5923317961811347,-0.37966711166030426,-0.2645349940023304,0.19607443889255075,0.06514870608694326,0.17017548246536693,4.05454044544889,3.3299572675677735,0.7327741710393836,0.8691530690352253,2.119398055387944,-0.7112482098625537,1.172767077784285,0.0916230653837448,-0.17996198897025922,0.8241310428665671,0.32349580032456454,0.616030896851247,0.11795129526109982,0.7327741710393836,0.39833990773856,0.17017548246536693,-0.9675239012000673,1.023417311456126,0.9137480795405156
| 3,120
|
Organophosphate catabolic process
| 6
| 36
| 2.321398
| 0.020265
|
A8MXV4,Q8NHP8,Q9NX62,Q10713,Q8NCC3,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
155,37,137,105,21,28
|
155,1963,1029,1202,2623,2571,2426,1070,1913,1438,605,2060,2256,2724,3031,2216,2398,1786,2223,105,1050,2358,1691,1837,21,37,28,1953,1188,2875,175,137,2957,1242,2769,1375
|
1.5362117181364128,-0.29306044672954845,0.24745340385816628,0.14413493056950505,-0.7740586736982547,-0.7112482098625537,-0.5880217491572218,0.22183326505174678,-0.2645349940023304,0.011755338385683791,0.5923317961811347,-0.35062453129738713,-0.46786141367036915,-0.902175152364751,-1.6363177401147757,-0.4382834749199662,-0.5576999615504026,-0.17996198897025922,-0.4382834749199662,1.9092431533941194,0.24745340385816628,-0.5275674680675104,-0.12439757025387724,-0.20798764245173287,3.7786917531689994,3.1288498896389405,3.369120265484028,-0.2645349940023304,0.17017548246536693,-1.1009154766800557,1.4775738794299105,1.651310887354022,-1.3081044921965708,0.14413493056950505,-0.9347396848564197,0.06514870608694326
| 3,120
|
Myoclonus
| 16
| 98
| 2.317189
| 0.020493
|
Q03252,O14773,Q14108,Q01105,Q9UQN3,Q96F07,Q9Y4G8,Q10713,P13073,P00374,Q13510,P50897,P00846,Q9NQZ5,Q96CU9,O75503
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
255,66,67,98,132,325,168,105,42,298,44,51,52,181,25,27
|
1522,2774,2564,2454,66,2531,2878,27,1588,1480,1910,2017,1631,298,604,52,1386,3087,1773,2937,1534,1912,1676,42,1115,1389,2336,2539,2387,834,2540,568,1645,2339,1781,2833,1723,51,1121,958,2578,1215,2162,569,2221,470,1933,98,255,1446,2634,105,1733,2867,44,394,67,2548,1450,3047,2885,2953,2872,1313,2183,1886,413,692,25,2713,2124,325,1605,1696,1319,1187,1606,1365,900,2366,1611,1103,1189,1661,2240,463,181,2327,795,2372,797,975,1614,132,1110,168,345,2934
|
-0.042241579625993585,-0.9675239012000673,-0.7112482098625537,-0.6185351182463072,2.385428384194839,-0.6801459566044995,-1.1348420125464262,3.44643436310832,-0.0694704733838678,-0.015166862701093613,-0.2645349940023304,-0.3217563066408477,-0.09685523182921355,1.0450468054585367,0.5923317961811347,2.7276227820437797,0.038526658332115674,-2.499432291736275,-0.17996198897025922,-1.2729570159514279,-0.042241579625993585,-0.2645349940023304,-0.12439757025387724,2.875037373385399,0.19607443889255075,0.038526658332115674,-0.5275674680675104,-0.6801459566044995,-0.5576999615504026,0.39833990773856,-0.6801459566044995,0.6396116988763457,-0.09685523182921355,-0.5275674680675104,-0.17996198897025922,-1.0337628479999912,-0.15209923198018688,2.757491625277111,0.19607443889255075,0.298283282312465,-0.7112482098625537,0.14413493056950505,-0.4088860728488319,0.6396116988763457,-0.4382834749199662,0.7786741122076469,-0.2645349940023304,1.9979768307458792,1.1517209730784248,0.011755338385683791,-0.7740586736982547,1.9092431533941194,-0.15209923198018688,-1.1009154766800557,2.860509873296997,0.8691530690352253,2.385428384194839,-0.6801459566044995,0.011755338385683791,-1.7507804815018162,-1.1348420125464262,-1.3081044921965708,-1.1009154766800557,0.0916230653837448,-0.4088860728488319,-0.23617802356071166,0.8466959209611702,0.5205132181705904,3.4719119012676685,-0.8698275055005745,-0.37966711166030426,0.979856683830239,-0.0694704733838678,-0.12439757025387724,0.0916230653837448,0.17017548246536693,-0.0694704733838678,0.06514870608694326,0.3485751885508132,-0.5275674680675104,-0.0694704733838678,0.22183326505174678,0.17017548246536693,-0.09685523182921355,-0.4382834749199662,0.8014574420423553,1.4578623634759529,-0.4976220214613302,0.4475879086837396,-0.5275674680675104,0.4475879086837396,0.298283282312465,-0.0694704733838678,1.7078061122023387,0.22183326505174678,1.516747891198495,0.9579237536502591,-1.238060398252917
| 3,120
|
Clumsiness
| 6
| 22
| 2.302456
| 0.021309
|
O14773,O75503,Q13510,O43819,Q13501,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,27,44,239,382,126
|
2291,66,2088,1768,239,27,450,2387,1871,1159,2339,1446,382,44,777,1175,1457,2641,1606,126,2372,2417
|
-0.4976220214613302,2.385428384194839,-0.37966711166030426,-0.17996198897025922,1.2145771446757452,3.44643436310832,0.8014574420423553,-0.5576999615504026,-0.23617802356071166,0.17017548246536693,-0.5275674680675104,0.011755338385683791,0.8915034664671595,2.860509873296997,0.4475879086837396,0.17017548246536693,0.011755338385683791,-0.7740586736982547,-0.0694704733838678,1.763620063558507,-0.5275674680675104,-0.5576999615504026
| 3,120
|
Organic acid transmembrane transporter activity
| 10
| 20
| 2.298927
| 0.021509
|
P08183,Q9H2H9,Q9UBX3,P41440,Q9UJS0,O95563,Q9BQT8,Q96NB2,Q9H2D1,P30825
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,758,797,73,602,550,480,575,61,63
|
1149,1587,550,64,912,63,73,2706,2397,1594,1224,1689,575,480,61,758,1661,820,797,602
|
0.17017548246536693,-0.0694704733838678,0.6630753264781283,2.401552801979837,0.32349580032456454,2.449587253406975,2.3039419144770994,-0.8698275055005745,-0.5576999615504026,-0.0694704733838678,0.14413493056950505,-0.12439757025387724,0.6396116988763457,0.7786741122076469,2.4813316430188412,0.47202132781882844,-0.09685523182921355,0.42302785571210444,0.4475879086837396,0.616030896851247
| 3,120
|
Abnormal sternum morphology
| 33
| 112
| 2.292366
| 0.021885
|
P02545,Q69YQ0,Q9UHX1,P57740,Q7LGA3,Q9Y487,O75962,P16278,P55795,Q8NCH0,Q7RTS9,Q96AY3,Q96L58,P50402,Q9NWH9,Q13510,P98175,Q02127,Q14999,Q15555,Q9Y2W2,Q15056,P61978,P06753,Q96S52,O95831,Q6DKJ4,O75431,O96028,O75718,O00330,P08236,P21912
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,136,397,393,19,150,273,283,404,161,32,436,166,289,443,44,426,427,430,431,330,323,322,450,341,86,220,464,347,346,483,247,378
|
483,2501,2204,2331,2423,2878,2503,1528,1431,1905,2014,464,346,273,2806,909,86,347,376,1773,450,1435,247,283,1536,2573,2938,378,1638,1390,1640,1870,2434,2388,1644,2389,1160,2847,289,1121,1592,2159,958,2706,2030,808,404,393,2517,322,2106,2897,998,426,427,2916,1548,1219,2583,1549,1942,44,2785,1450,746,430,323,778,431,1130,136,220,2664,19,32,2316,2734,161,2073,2641,543,506,591,693,436,2363,2125,166,2000,341,1054,2189,1755,2668,970,793,2195,1107,443,397,2669,1193,2960,762,2618,2134,1421,330,150,1244,1286,2907
|
0.75578003326324,-0.6492423972397605,-0.4382834749199662,-0.5275674680675104,-0.5880217491572218,-1.1348420125464262,-0.6492423972397605,-0.042241579625993585,0.011755338385683791,-0.2645349940023304,-0.3217563066408477,0.7786741122076469,0.9358878616746352,1.1093425443192109,-1.000530653277979,0.32349580032456454,2.119398055387944,0.9358878616746352,0.8915034664671595,-0.17996198897025922,0.8014574420423553,0.011755338385683791,1.172767077784285,1.0880085580638097,-0.042241579625993585,-0.7112482098625537,-1.2729570159514279,0.8915034664671595,-0.09685523182921355,0.038526658332115674,-0.09685523182921355,-0.23617802356071166,-0.5880217491572218,-0.5576999615504026,-0.09685523182921355,-0.5576999615504026,0.17017548246536693,-1.0672234487170145,1.0665769311873845,0.19607443889255075,-0.0694704733838678,-0.4088860728488319,0.298283282312465,-0.8698275055005745,-0.3217563066408477,0.42302785571210444,0.8466959209611702,0.8691530690352253,-0.6492423972397605,0.979856683830239,-0.37966711166030426,-1.169006197935009,0.2729362763877655,0.8241310428665671,0.8241310428665671,-1.2034112370325538,-0.042241579625993585,0.14413493056950505,-0.7112482098625537,-0.042241579625993585,-0.2645349940023304,2.860509873296997,-0.9675239012000673,0.011755338385683791,0.47202132781882844,0.8241310428665671,0.979856683830239,0.4475879086837396,0.8241310428665671,0.19607443889255075,1.6702193073777245,1.2765988138362,-0.8057719361207141,3.9302356800799503,3.210375491197299,-0.4976220214613302,-0.902175152364751,1.5362117181364128,-0.35062453129738713,-0.7740586736982547,0.6864228881683501,0.7327741710393836,0.616030896851247,0.5205132181705904,0.8241310428665671,-0.5275674680675104,-0.37966711166030426,1.516747891198495,-0.29306044672954845,0.9579237536502591,0.24745340385816628,-0.4088860728488319,-0.15209923198018688,-0.8057719361207141,0.298283282312465,0.4475879086837396,-0.4088860728488319,0.22183326505174678,0.8241310428665671,0.8691530690352253,-0.8057719361207141,0.17017548246536693,-1.3081044921965708,0.47202132781882844,-0.7425516146318213,-0.37966711166030426,0.038526658332115674,0.979856683830239,1.5748962832288216,0.14413493056950505,0.11795129526109982,-1.169006197935009
| 3,120
|
Abnormal form of the vertebral bodies
| 24
| 86
| 2.290347
| 0.022001
|
Q8TAA9,Q9UHX1,Q96HY6,P54802,P04066,P16278,Q7RTS9,Q96AY3,Q96L58,P48735,P39019,Q14999,Q9Y2W2,Q15056,Q32P28,O95831,O60826,Q15427,Q9H0W5,Q10713,O96028,P15586,P08236,Q5JRA6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,397,528,264,282,283,32,436,166,306,425,430,330,323,74,86,331,490,492,105,347,111,247,384
|
2203,2204,2088,1377,2331,2423,2503,627,331,2014,1588,1202,2806,909,86,347,1070,282,1632,247,807,111,283,1209,1635,1389,2573,2938,1638,708,2433,2434,2388,1644,1302,1542,425,306,1120,2159,264,1930,2977,998,1444,1786,1548,1219,105,522,1942,746,1738,430,323,490,1554,74,2268,1455,384,1308,663,32,2524,866,131,436,528,166,3012,2888,492,793,2241,2595,2597,397,2669,1194,1421,2374,330,1374,1286,1028
|
-0.4382834749199662,-0.4382834749199662,-0.37966711166030426,0.038526658332115674,-0.5275674680675104,-0.5880217491572218,-0.6492423972397605,0.5685132566383815,0.9579237536502591,-0.3217563066408477,-0.0694704733838678,0.14413493056950505,-1.000530653277979,0.32349580032456454,2.119398055387944,0.9358878616746352,0.22183326505174678,1.0880085580638097,-0.09685523182921355,1.172767077784285,0.42302785571210444,1.8370056925799199,1.0880085580638097,0.14413493056950505,-0.09685523182921355,0.038526658332115674,-0.7112482098625537,-1.2729570159514279,-0.09685523182921355,0.4963293559988893,-0.5880217491572218,-0.5880217491572218,-0.5576999615504026,-0.09685523182921355,0.0916230653837448,-0.042241579625993585,0.8241310428665671,1.023417311456126,0.19607443889255075,-0.4088860728488319,1.1305797371850148,-0.2645349940023304,-1.379165978216167,0.2729362763877655,0.011755338385683791,-0.17996198897025922,-0.042241579625993585,0.14413493056950505,1.9092431533941194,0.709655477037906,-0.2645349940023304,0.47202132781882844,-0.15209923198018688,0.8241310428665671,0.979856683830239,0.75578003326324,-0.042241579625993585,2.3039419144770994,-0.46786141367036915,0.011755338385683791,0.8915034664671595,0.0916230653837448,0.5445741216866079,3.210375491197299,-0.6492423972397605,0.37352278495630703,1.7078061122023387,0.8241310428665671,0.709655477037906,1.516747891198495,-1.5244569016571512,-1.1348420125464262,0.75578003326324,0.4475879086837396,-0.4382834749199662,-0.7112482098625537,-0.7112482098625537,0.8691530690352253,-0.8057719361207141,0.17017548246536693,0.038526658332115674,-0.5275674680675104,0.979856683830239,0.06514870608694326,0.11795129526109982,0.2729362763877655
| 3,120
|
Programmed cell death
| 18
| 99
| 2.289721
| 0.022038
|
P02545,O00231,Q9UQN3,Q13813,P20700,P41440,P08670,Q9Y3E7,Q16625,O60313,Q07021,Q96E52,P28072,P28070,P49721,P28074,Q9NR28,P31751
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
376,374,132,394,288,73,139,203,266,389,408,179,117,53,23,151,251,183
|
374,2601,2087,1197,1861,978,1670,1150,1710,389,2380,878,376,2093,1633,1436,139,1483,1675,1031,1076,1485,916,630,288,708,2511,553,2097,2975,1537,989,831,2627,53,117,151,2155,2257,183,832,1642,991,1924,2101,73,1978,1979,2214,2157,1164,23,862,1822,2027,2343,835,1399,569,996,1545,682,2543,1124,2898,1400,2223,407,408,836,1940,2635,1090,2224,394,1223,1092,1651,1685,1001,1454,266,1950,2486,179,2079,670,1840,2192,251,649,947,1579,650,1062,1667,2133,132,203
|
0.8915034664671595,-0.7425516146318213,-0.37966711166030426,0.14413493056950505,-0.23617802356071166,0.2729362763877655,-0.12439757025387724,0.17017548246536693,-0.15209923198018688,0.8691530690352253,-0.5576999615504026,0.3485751885508132,0.8915034664671595,-0.37966711166030426,-0.09685523182921355,0.011755338385683791,1.6323249879473072,-0.015166862701093613,-0.12439757025387724,0.24745340385816628,0.22183326505174678,-0.015166862701093613,0.32349580032456454,0.5685132566383815,1.0665769311873845,0.4963293559988893,-0.6492423972397605,0.6630753264781283,-0.37966711166030426,-1.379165978216167,-0.042241579625993585,0.2729362763877655,0.39833990773856,-0.7740586736982547,2.71261432511635,1.8004585753415925,1.555594300107399,-0.4088860728488319,-0.46786141367036915,1.4380669400587471,0.39833990773856,-0.09685523182921355,0.2729362763877655,-0.2645349940023304,-0.37966711166030426,2.3039419144770994,-0.29306044672954845,-0.29306044672954845,-0.4382834749199662,-0.4088860728488319,0.17017548246536693,3.706966810655375,0.37352278495630703,-0.20798764245173287,-0.3217563066408477,-0.5275674680675104,0.39833990773856,0.038526658332115674,0.6396116988763457,0.2729362763877655,-0.042241579625993585,0.5205132181705904,-0.6801459566044995,0.19607443889255075,-1.169006197935009,0.038526658332115674,-0.4382834749199662,0.8466959209611702,0.8466959209611702,0.39833990773856,-0.2645349940023304,-0.7740586736982547,0.22183326505174678,-0.4382834749199662,0.8691530690352253,0.14413493056950505,0.22183326505174678,-0.09685523182921355,-0.12439757025387724,0.2729362763877655,0.011755338385683791,1.1305797371850148,-0.2645349940023304,-0.6185351182463072,1.4578623634759529,-0.35062453129738713,0.5445741216866079,-0.20798764245173287,-0.4088860728488319,1.172767077784285,0.5685132566383815,0.32349580032456454,-0.042241579625993585,0.5685132566383815,0.24745340385816628,-0.09685523182921355,-0.37966711166030426,1.7078061122023387,1.3378069158806978
| 3,120
|
Oxidative phosphorylation
| 20
| 62
| 2.286549
| 0.022222
|
O75947,Q9Y487,O14949,P13073,P00846,P36542,Q9UDW1,P22695,Q15904,P14406,Q9Y6N1,Q7KZN9,P36543,P14927,P24539,Q93050,P20674,O75964,O96000,P21912
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
252,150,26,42,52,305,56,303,186,72,204,335,213,93,94,99,349,114,124,378
|
3109,1522,388,26,3070,2602,2909,2294,2505,1152,252,114,654,1711,984,2425,124,604,52,3087,422,1774,913,2383,42,72,93,1388,2152,349,1389,859,378,303,94,919,1342,2387,2513,305,213,1645,2575,955,2833,2927,2849,883,2163,2900,186,716,1002,335,3085,99,2821,56,1763,150,764,204
|
-3.4883531035688655,-0.042241579625993585,0.8691530690352253,3.459191262825689,-2.0696602571110043,-0.7425516146318213,-1.2034112370325538,-0.4976220214613302,-0.6492423972397605,0.17017548246536693,1.1517209730784248,1.818768282448762,0.5445741216866079,-0.15209923198018688,0.2729362763877655,-0.5880217491572218,1.763620063558507,0.5923317961811347,2.7276227820437797,-2.499432291736275,0.8241310428665671,-0.17996198897025922,0.32349580032456454,-0.5576999615504026,2.875037373385399,2.336710950263473,2.050407604865225,0.038526658332115674,-0.4088860728488319,0.9358878616746352,0.038526658332115674,0.37352278495630703,0.8915034664671595,1.023417311456126,2.050407604865225,0.32349580032456454,0.06514870608694326,-0.5576999615504026,-0.6492423972397605,1.023417311456126,1.297090899466863,-0.09685523182921355,-0.7112482098625537,0.298283282312465,-1.0337628479999912,-1.238060398252917,-1.0672234487170145,0.3485751885508132,-0.4088860728488319,-1.169006197935009,1.4380669400587471,0.4963293559988893,0.2729362763877655,0.9579237536502591,-2.41046038039257,1.9979768307458792,-1.000530653277979,2.575259739826172,-0.15209923198018688,1.5748962832288216,0.47202132781882844,1.3378069158806978
| 3,120
|
Hyperlipidemia
| 16
| 30
| 2.285462
| 0.022286
|
P02545,O75431,Q969N2,P23786,P50402,P38571,O95470,P06280,Q13045,P28070,P31751,P22830,Q96MF7,Q8WXH0,O75844,Q92734
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,464,506,379,289,486,449,232,522,53,183,304,162,543,123,386
|
2088,981,464,123,449,376,232,2019,304,379,53,1538,183,2629,486,1397,289,1082,2609,522,2785,3092,2641,543,386,506,162,1054,602,2053
|
-0.37966711166030426,0.2729362763877655,0.7786741122076469,1.763620063558507,0.8014574420423553,0.8915034664671595,1.2353427068536198,-0.3217563066408477,1.023417311456126,0.8915034664671595,2.71261432511635,-0.042241579625993585,1.4380669400587471,-0.7740586736982547,0.75578003326324,0.038526658332115674,1.0665769311873845,0.22183326505174678,-0.7425516146318213,0.709655477037906,-0.9675239012000673,-2.6359322040956585,-0.7740586736982547,0.6864228881683501,0.8915034664671595,0.7327741710393836,1.5362117181364128,0.24745340385816628,0.616030896851247,-0.3217563066408477
| 3,120
|
Intermediate filament, rod domain [IPR039008]
| 7
| 8
| 2.274182
| 0.022955
|
P02545,Q03252,P07196,P20700,Q16352,P08670,P07197
|
Sequence
|
InterPro Domain
|
interpro_domain
|
376,255,103,288,556,139,423
|
376,103,423,139,288,660,255,556
|
0.8915034664671595,1.9271271193823978,0.8241310428665671,1.6323249879473072,1.0665769311873845,0.5445741216866079,1.1517209730784248,0.6630753264781283
| 3,120
|
Intermediate filament protein, conserved site [IPR018039]
| 7
| 8
| 2.274182
| 0.022955
|
P02545,Q03252,P07196,P20700,Q16352,P08670,P07197
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
376,255,103,288,556,139,423
|
376,103,423,139,288,660,255,556
|
0.8915034664671595,1.9271271193823978,0.8241310428665671,1.6323249879473072,1.0665769311873845,0.5445741216866079,1.1517209730784248,0.6630753264781283
| 3,120
|
Atp synthesis coupled proton transport
| 6
| 12
| 2.272674
| 0.023046
|
O75947,O75964,P00846,P06576,P36542,P24539
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
252,114,52,422,305,94
|
252,114,52,422,94,919,305,1645,955,2849,883,512
|
1.1517209730784248,1.818768282448762,2.7276227820437797,0.8241310428665671,2.050407604865225,0.32349580032456454,1.023417311456126,-0.09685523182921355,0.298283282312465,-1.0672234487170145,0.3485751885508132,0.7327741710393836
| 3,120
|
Intermediate filament cytoskeleton
| 14
| 32
| 2.270241
| 0.023193
|
P02545,Q03252,Q9UNZ2,P07196,P20700,P08670,Q16352,Q9NZQ3,Q9UPN3,O75298,Q3SXM5,P07197,Q8WXH0,Q03001
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
376,255,624,103,288,139,556,202,373,110,368,423,543,500
|
1334,110,2380,376,103,423,139,1820,1031,288,660,1928,2393,2031,1727,500,255,2636,1001,556,1654,368,2353,543,816,1057,2717,1703,202,824,624,373
|
0.06514870608694326,1.8551713497297029,-0.5576999615504026,0.8915034664671595,1.9271271193823978,0.8241310428665671,1.6323249879473072,-0.20798764245173287,0.24745340385816628,1.0665769311873845,0.5445741216866079,-0.2645349940023304,-0.5576999615504026,-0.3217563066408477,-0.15209923198018688,0.7327741710393836,1.1517209730784248,-0.7740586736982547,0.2729362763877655,0.6630753264781283,-0.09685523182921355,0.9137480795405156,-0.5275674680675104,0.6864228881683501,0.42302785571210444,0.24745340385816628,-0.8698275055005745,-0.12439757025387724,1.3378069158806978,0.42302785571210444,0.5923317961811347,0.9137480795405156
| 3,120
|
Rhod gtpase cycle
| 14
| 28
| 2.269571
| 0.023234
|
O00459,Q8TAA9,P50402,P20700,Q9UEY8,Q9Y2U8,Q14739,P42167,P12814,Q5JTV8,Q9H0H5,Q9BX68,Q8NHP6,P42166
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
156,131,289,288,728,763,746,207,733,432,757,872,869,467
|
156,1292,1201,1295,733,288,467,207,2726,1397,289,2064,1445,746,864,432,2119,869,131,1186,969,872,757,1664,1665,728,763,1196
|
1.5362117181364128,0.0916230653837448,0.14413493056950505,0.0916230653837448,0.47202132781882844,1.0665769311873845,0.7786741122076469,1.3174933512024687,-0.902175152364751,0.038526658332115674,1.0665769311873845,-0.35062453129738713,0.011755338385683791,0.47202132781882844,0.37352278495630703,0.8241310428665671,-0.37966711166030426,0.37352278495630703,1.7078061122023387,0.17017548246536693,0.298283282312465,0.37352278495630703,0.47202132781882844,-0.09685523182921355,-0.09685523182921355,0.4963293559988893,0.47202132781882844,0.17017548246536693
| 3,120
|
Receptor mediated endocytosis
| 9
| 51
| 2.267378
| 0.023367
|
Q14108,P61978,P41440,P11717,P20645,P02786,Q5VW38,P50897,P62993
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
67,322,73,233,46,172,47,51,148
|
978,1964,2089,2504,878,1204,2333,172,911,2703,828,655,1714,233,1075,1158,46,1391,658,73,1343,1724,51,2342,322,148,1546,2475,1933,2033,685,1736,67,1449,961,1352,2117,47,2732,369,2183,2713,939,900,1058,1327,3036,1579,1852,854,2600
|
0.2729362763877655,-0.29306044672954845,-0.37966711166030426,-0.6492423972397605,0.3485751885508132,0.14413493056950505,-0.5275674680675104,1.4775738794299105,0.32349580032456454,-0.8698275055005745,0.39833990773856,0.5445741216866079,-0.15209923198018688,1.2353427068536198,0.22183326505174678,0.17017548246536693,2.831314292458711,0.038526658332115674,0.5445741216866079,2.3039419144770994,0.06514870608694326,-0.15209923198018688,2.757491625277111,-0.5275674680675104,0.979856683830239,1.5748962832288216,-0.042241579625993585,-0.6185351182463072,-0.2645349940023304,-0.3217563066408477,0.5205132181705904,-0.15209923198018688,2.385428384194839,0.011755338385683791,0.298283282312465,0.06514870608694326,-0.37966711166030426,2.816645631587557,-0.902175152364751,0.9137480795405156,-0.4088860728488319,-0.8698275055005745,0.32349580032456454,0.3485751885508132,0.24745340385816628,0.0916230653837448,-1.6363177401147757,-0.042241579625993585,-0.20798764245173287,0.39833990773856,-0.7112482098625537
| 3,120
|
Aplasia hypoplasia of toe
| 11
| 32
| 2.265747
| 0.023467
|
P02545,Q69YQ0,Q9UHX1,Q9NX62,P13073,O96028,Q13510,Q96PZ0,Q7LGA3,O75648,Q5JRA6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,136,397,137,42,347,44,371,19,421,384
|
2601,951,421,909,2570,347,1070,376,807,42,2573,708,2337,2339,808,1826,1942,44,1788,490,1455,384,136,19,2316,3042,784,371,970,137,2597,397
|
-0.7425516146318213,0.298283282312465,0.8241310428665671,0.32349580032456454,-0.7112482098625537,0.9358878616746352,0.22183326505174678,0.8915034664671595,0.42302785571210444,2.875037373385399,-0.7112482098625537,0.4963293559988893,-0.5275674680675104,-0.5275674680675104,0.42302785571210444,-0.20798764245173287,-0.2645349940023304,2.860509873296997,-0.17996198897025922,0.75578003326324,0.011755338385683791,0.8915034664671595,1.6702193073777245,3.9302356800799503,-0.4976220214613302,-1.712329994309814,0.4475879086837396,0.9137480795405156,0.298283282312465,1.651310887354022,-0.7112482098625537,0.8691530690352253
| 3,120
|
Protein localization
| 16
| 70
| 2.264866
| 0.023521
|
A8MXV4,Q15388,Q8N4H5,P50402,Q10713,Q13011,Q9BY49,Q13505,O14925,O60830,Q9NX63,Q9NS69,P46379,P51648,Q9NR77,P21796
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
155,294,70,289,105,106,300,76,171,176,312,261,90,91,126,160
|
155,950,171,1377,1427,1030,1768,515,1066,2845,176,1906,2506,464,1814,1337,1587,1202,1629,1711,1631,422,1774,2021,770,1715,2808,2536,2096,160,1211,919,2212,2540,1542,1035,90,289,91,1592,2941,924,105,106,1941,76,777,294,841,307,3008,70,2183,2232,2555,1889,2741,300,972,126,261,312,2197,2798,602,1476,876,702,2719,3090
|
1.5362117181364128,0.298283282312465,1.4775738794299105,0.038526658332115674,0.011755338385683791,0.24745340385816628,-0.17996198897025922,0.709655477037906,0.22183326505174678,-1.0672234487170145,1.4578623634759529,-0.2645349940023304,-0.6492423972397605,0.7786741122076469,-0.20798764245173287,0.06514870608694326,-0.0694704733838678,0.14413493056950505,-0.09685523182921355,-0.15209923198018688,-0.09685523182921355,0.8241310428665671,-0.17996198897025922,-0.3217563066408477,0.4475879086837396,-0.15209923198018688,-1.000530653277979,-0.6801459566044995,-0.37966711166030426,1.5362117181364128,0.14413493056950505,0.32349580032456454,-0.4382834749199662,-0.6801459566044995,-0.042241579625993585,0.24745340385816628,2.0677525498216016,1.0665769311873845,2.0677525498216016,-0.0694704733838678,-1.2729570159514279,0.32349580032456454,1.9092431533941194,1.9092431533941194,-0.2645349940023304,2.2376915434747073,0.4475879086837396,1.0665769311873845,0.39833990773856,1.023417311456126,-1.4877287999834443,2.3692468623114746,-0.4088860728488319,-0.4382834749199662,-0.6801459566044995,-0.23617802356071166,-0.902175152364751,1.0450468054585367,0.298283282312465,1.763620063558507,1.1517209730784248,1.023417311456126,-0.4088860728488319,-0.9675239012000673,0.616030896851247,0.011755338385683791,0.37352278495630703,0.5205132181705904,-0.8698275055005745,-2.499432291736275
| 3,120
|
Lipodystrophy
| 15
| 35
| 2.262091
| 0.023692
|
P02545,Q03252,O75431,P09493,P50402,P42167,P39656,Q9Y487,P28070,P31751,P36543,P04066,Q8WXH0,O75844,P42166
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,255,464,629,289,207,583,150,53,183,213,282,543,123,467
|
2088,464,2970,676,123,376,282,629,1031,917,2573,53,1538,2387,183,213,1645,583,467,207,289,2162,255,2785,1223,1308,2641,543,2277,1054,1322,1899,1853,1375,150
|
-0.37966711166030426,0.7786741122076469,-1.379165978216167,0.5205132181705904,1.763620063558507,0.8915034664671595,1.0880085580638097,0.5685132566383815,0.24745340385816628,0.32349580032456454,-0.7112482098625537,2.71261432511635,-0.042241579625993585,-0.5576999615504026,1.4380669400587471,1.297090899466863,-0.09685523182921355,0.616030896851247,0.7786741122076469,1.3174933512024687,1.0665769311873845,-0.4088860728488319,1.1517209730784248,-0.9675239012000673,0.14413493056950505,0.0916230653837448,-0.7740586736982547,0.6864228881683501,-0.46786141367036915,0.24745340385816628,0.0916230653837448,-0.23617802356071166,-0.20798764245173287,0.06514870608694326,1.5748962832288216
| 3,120
|
Negative regulation of rna splicing
| 12
| 19
| 2.260414
| 0.023796
|
O00422,Q16629,P61978,P22626,P38159,Q13242,P98175,P26368,O75494,Q08170,Q07021,Q13247
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
652,227,322,321,140,234,426,737,803,774,408,570
|
652,803,321,737,1033,140,2218,322,2310,426,408,774,885,234,570,1452,227,1274,1328
|
0.5445741216866079,0.42302785571210444,0.979856683830239,0.47202132781882844,0.24745340385816628,1.6323249879473072,-0.4382834749199662,0.979856683830239,-0.4976220214613302,0.8241310428665671,0.8466959209611702,0.4475879086837396,0.3485751885508132,1.2353427068536198,0.6396116988763457,0.011755338385683791,1.256016338166523,0.11795129526109982,0.0916230653837448
| 3,120
|
Endocytic vesicle
| 13
| 87
| 2.234341
| 0.025461
|
O15400,Q93050,Q14108,Q9Y4G8,P08670,Q969Q5,P11717,P20645,P02786,Q15907,P10321,Q9Y487,Q8WTV0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
218,99,67,168,139,108,233,46,172,49,240,150,28
|
2936,1857,1858,1376,218,704,766,1966,2014,1380,1204,2333,1154,172,1071,2703,1436,139,655,1714,240,1073,2149,233,2384,1484,734,1158,46,1974,1920,954,2466,1724,1442,1782,2064,3055,1876,2217,2342,2517,1984,498,1823,1086,2163,2475,1933,1786,1219,1169,685,2477,2584,67,1092,1833,1686,540,2117,49,2226,266,1048,638,2761,1996,1746,1355,28,1799,99,108,2713,1368,511,851,1059,3036,1371,2617,2008,150,168,1244,854
|
-1.2729570159514279,-0.23617802356071166,-0.23617802356071166,0.038526658332115674,1.2765988138362,0.4963293559988893,0.4475879086837396,-0.29306044672954845,-0.3217563066408477,0.038526658332115674,0.14413493056950505,-0.5275674680675104,0.17017548246536693,1.4775738794299105,0.22183326505174678,-0.8698275055005745,0.011755338385683791,1.6323249879473072,0.5445741216866079,-0.15209923198018688,1.2145771446757452,0.22183326505174678,-0.4088860728488319,1.2353427068536198,-0.5576999615504026,-0.015166862701093613,0.47202132781882844,0.17017548246536693,2.831314292458711,-0.29306044672954845,-0.2645349940023304,0.298283282312465,-0.6185351182463072,-0.15209923198018688,0.011755338385683791,-0.17996198897025922,-0.35062453129738713,-1.8285925507530927,-0.23617802356071166,-0.4382834749199662,-0.5275674680675104,-0.6492423972397605,-0.29306044672954845,0.7327741710393836,-0.20798764245173287,0.22183326505174678,-0.4088860728488319,-0.6185351182463072,-0.2645349940023304,-0.17996198897025922,0.14413493056950505,0.17017548246536693,0.5205132181705904,-0.6185351182463072,-0.7112482098625537,2.385428384194839,0.22183326505174678,-0.20798764245173287,-0.12439757025387724,0.6864228881683501,-0.37966711166030426,2.801929332566857,-0.4382834749199662,1.1305797371850148,0.24745340385816628,0.5685132566383815,-0.9347396848564197,-0.29306044672954845,-0.15209923198018688,0.06514870608694326,3.369120265484028,-0.17996198897025922,1.9979768307458792,1.873265791868123,-0.8698275055005745,0.06514870608694326,0.7327741710393836,0.39833990773856,0.24745340385816628,-1.6363177401147757,0.06514870608694326,-0.7425516146318213,-0.29306044672954845,1.5748962832288216,1.516747891198495,0.14413493056950505,0.39833990773856
| 3,120
|
Sensorimotor neuropathy
| 10
| 30
| 2.228858
| 0.025823
|
Q9Y2R0,P07196,Q13217,P41440,Q9Y4W6,Q9NSE4,P00846,O95831,Q9NR77,Q92734
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
2,103,197,73,345,344,52,86,126,386
|
1197,2804,389,86,604,52,3087,1249,103,1210,3003,2948,2338,73,1723,1592,1215,2398,2438,1733,197,1000,2761,2358,386,126,344,2372,2,345
|
0.14413493056950505,-1.000530653277979,0.8691530690352253,2.119398055387944,0.5923317961811347,2.7276227820437797,-2.499432291736275,0.11795129526109982,1.9271271193823978,0.14413493056950505,-1.4877287999834443,-1.3081044921965708,-0.5275674680675104,2.3039419144770994,-0.15209923198018688,-0.0694704733838678,0.14413493056950505,-0.5576999615504026,-0.5880217491572218,-0.15209923198018688,1.3580323311839413,0.2729362763877655,-0.9347396848564197,-0.5275674680675104,0.8915034664671595,1.763620063558507,0.9579237536502591,-0.5275674680675104,4.875529536020904,0.9579237536502591
| 3,120
|
EF-hand domain [IPR002048]
| 14
| 42
| 2.227083
| 0.025942
|
Q13813,Q96AY3,Q9BPX6,O43852,Q99653,Q9UJS0,Q9UPN3,P80303,Q9UBV8,Q9H223,Q14257,Q15293,Q02818,Q03001
|
Sequence
|
InterPro Domain
|
interpro_domain
|
394,436,595,134,558,602,373,15,314,511,87,249,30,500
|
981,134,856,1587,909,2675,733,2893,1300,2302,605,2100,1922,1119,1343,1162,2783,15,30,500,394,87,2585,249,1174,1308,1797,750,868,436,1186,939,558,595,1272,511,851,1192,2797,314,602,373
|
0.2729362763877655,1.6702193073777245,0.37352278495630703,-0.0694704733838678,0.32349580032456454,-0.8376939983695894,0.47202132781882844,-1.169006197935009,0.0916230653837448,-0.4976220214613302,0.5923317961811347,-0.37966711166030426,-0.2645349940023304,0.19607443889255075,0.06514870608694326,0.17017548246536693,-0.9675239012000673,4.05454044544889,3.3299572675677735,0.7327741710393836,0.8691530690352253,2.119398055387944,-0.7112482098625537,1.172767077784285,0.17017548246536693,0.0916230653837448,-0.17996198897025922,0.47202132781882844,0.37352278495630703,0.8241310428665671,0.17017548246536693,0.32349580032456454,0.6630753264781283,0.616030896851247,0.11795129526109982,0.7327741710393836,0.39833990773856,0.17017548246536693,-0.9675239012000673,1.023417311456126,0.616030896851247,0.9137480795405156
| 3,120
|
Rac3 gtpase cycle
| 6
| 30
| 2.225416
| 0.026053
|
O00459,Q8TAA9,Q9UQB8,P02786,P42167,O75962
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
156,131,13,172,207,273
|
1857,156,2379,273,987,172,911,467,207,1397,289,2064,2517,1786,1827,1940,1223,746,1224,2119,1499,2522,131,1362,969,757,1664,13,2800,763
|
-0.23617802356071166,1.5362117181364128,-0.5576999615504026,1.1093425443192109,0.2729362763877655,1.4775738794299105,0.32349580032456454,0.7786741122076469,1.3174933512024687,0.038526658332115674,1.0665769311873845,-0.35062453129738713,-0.6492423972397605,-0.17996198897025922,-0.20798764245173287,-0.2645349940023304,0.14413493056950505,0.47202132781882844,0.14413493056950505,-0.37966711166030426,-0.015166862701093613,-0.6492423972397605,1.7078061122023387,0.06514870608694326,0.298283282312465,0.47202132781882844,-0.09685523182921355,4.164591374905695,-0.9675239012000673,0.47202132781882844
| 3,120
|
Proton transporting atp synthase complex
| 6
| 11
| 2.218876
| 0.026495
|
O75947,Q96IX5,O75964,P00846,P36542,P24539
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
252,230,114,52,305,94
|
252,114,52,422,94,919,305,955,2849,883,230
|
1.1517209730784248,1.818768282448762,2.7276227820437797,0.8241310428665671,2.050407604865225,0.32349580032456454,1.023417311456126,0.298283282312465,-1.0672234487170145,0.3485751885508132,1.256016338166523
| 3,120
|
Distal amyotrophy
| 19
| 61
| 2.218356
| 0.026531
|
P04792,P02545,Q9Y6X9,O60568,Q99720,Q99653,Q13510,Q8TD16,P06753,Q9Y4W6,Q9BQT8,O14908,O95140,P07196,Q92734,P35637,Q13501,Q9NR77,P21912
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,376,533,627,6,558,44,188,450,345,480,579,332,103,386,248,382,126,378
|
579,979,2804,1626,627,332,376,128,450,103,1917,378,2387,1871,2629,248,1487,861,2630,1723,1724,2064,2706,1215,2609,2398,2542,1219,1733,999,382,44,634,714,1992,1000,1653,1002,1556,1558,1094,1050,813,2358,2232,188,386,1800,2794,558,900,6,480,1755,126,1107,2562,1667,949,345,533
|
0.616030896851247,0.2729362763877655,-1.000530653277979,-0.09685523182921355,0.5685132566383815,0.9579237536502591,0.8915034664671595,1.7264856813353782,0.8014574420423553,1.9271271193823978,-0.2645349940023304,0.8915034664671595,-0.5576999615504026,-0.23617802356071166,-0.7740586736982547,1.172767077784285,-0.015166862701093613,0.37352278495630703,-0.7740586736982547,-0.15209923198018688,-0.15209923198018688,-0.35062453129738713,-0.8698275055005745,0.14413493056950505,-0.7425516146318213,-0.5576999615504026,-0.6801459566044995,0.14413493056950505,-0.15209923198018688,0.2729362763877655,0.8915034664671595,2.860509873296997,0.5685132566383815,0.4963293559988893,-0.29306044672954845,0.2729362763877655,-0.09685523182921355,0.2729362763877655,-0.042241579625993585,-0.042241579625993585,0.22183326505174678,0.24745340385816628,0.42302785571210444,-0.5275674680675104,-0.4382834749199662,1.4380669400587471,0.8915034664671595,-0.17996198897025922,-0.9675239012000673,0.6630753264781283,0.3485751885508132,4.647892361308431,0.7786741122076469,-0.15209923198018688,1.763620063558507,0.22183326505174678,-0.6801459566044995,-0.09685523182921355,0.32349580032456454,0.9579237536502591,0.709655477037906
| 3,120
|
Retinopathy
| 8
| 26
| 2.206216
| 0.027369
|
O00330,O96028,O43819,Q9NZ08,P00846,Q5JRA6,P51648,Q15555
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
483,347,239,145,52,384,91,431
|
483,239,1769,2294,1711,909,347,52,1154,1435,1157,2460,2101,2338,2214,91,1084,1942,431,1455,384,2318,1365,2366,530,145
|
0.75578003326324,1.2145771446757452,-0.17996198897025922,-0.4976220214613302,-0.15209923198018688,0.32349580032456454,0.9358878616746352,2.7276227820437797,0.17017548246536693,0.011755338385683791,0.17017548246536693,-0.6185351182463072,-0.37966711166030426,-0.5275674680675104,-0.4382834749199662,2.0677525498216016,0.22183326505174678,-0.2645349940023304,0.8241310428665671,0.011755338385683791,0.8915034664671595,-0.4976220214613302,0.06514870608694326,-0.5275674680675104,0.709655477037906,1.5941183060567525
| 3,120
|
Limb muscle weakness
| 16
| 85
| 2.192869
| 0.028317
|
Q7RTS9,P04792,Q99720,P07196,P50402,Q9Y4W6,Q13510,O75298,O43819,Q86U42,Q13126,P00846,O95140,Q13501,Q9NR77,Q92734
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,128,6,103,289,345,44,110,239,337,20,52,332,382,126,386
|
855,579,979,2804,239,110,677,332,52,376,128,1249,450,103,2675,2428,1715,2808,1917,1776,2938,2387,1871,1159,1118,568,2338,1487,2680,1781,1081,289,1724,2064,2706,1215,2609,2030,2398,2438,2162,1785,2758,1548,1733,2867,20,382,44,2785,714,2548,1992,746,2587,777,1000,1001,1130,1653,2227,1556,1558,32,1094,337,1050,813,2641,2232,543,386,692,1185,1800,2794,1606,1365,6,480,1054,126,2134,345,533
|
0.37352278495630703,0.616030896851247,0.2729362763877655,-1.000530653277979,1.2145771446757452,1.8551713497297029,0.5205132181705904,0.9579237536502591,2.7276227820437797,0.8915034664671595,1.7264856813353782,0.11795129526109982,0.8014574420423553,1.9271271193823978,-0.8376939983695894,-0.5880217491572218,-0.15209923198018688,-1.000530653277979,-0.2645349940023304,-0.17996198897025922,-1.2729570159514279,-0.5576999615504026,-0.23617802356071166,0.17017548246536693,0.19607443889255075,0.6396116988763457,-0.5275674680675104,-0.015166862701093613,-0.8376939983695894,-0.17996198897025922,0.22183326505174678,1.0665769311873845,-0.15209923198018688,-0.35062453129738713,-0.8698275055005745,0.14413493056950505,-0.7425516146318213,-0.3217563066408477,-0.5576999615504026,-0.5880217491572218,-0.4088860728488319,-0.17996198897025922,-0.9347396848564197,-0.042241579625993585,-0.15209923198018688,-1.1009154766800557,3.7786917531689994,0.8915034664671595,2.860509873296997,-0.9675239012000673,0.4963293559988893,-0.6801459566044995,-0.29306044672954845,0.47202132781882844,-0.7112482098625537,0.4475879086837396,0.2729362763877655,0.2729362763877655,0.19607443889255075,-0.09685523182921355,-0.4382834749199662,-0.042241579625993585,-0.042241579625993585,3.210375491197299,0.22183326505174678,0.9579237536502591,0.24745340385816628,0.42302785571210444,-0.7740586736982547,-0.4382834749199662,0.6864228881683501,0.8915034664671595,0.5205132181705904,0.17017548246536693,-0.17996198897025922,-0.9675239012000673,-0.0694704733838678,0.06514870608694326,4.647892361308431,0.7786741122076469,0.24745340385816628,1.763620063558507,-0.37966711166030426,0.9579237536502591,0.709655477037906
| 3,120
|
Rac2 gtpase cycle
| 13
| 32
| 2.192052
| 0.028376
|
O00459,Q8TAA9,P50402,Q9Y2U8,Q13505,P02786,Q9Y512,Q86XL3,P42167,Q14739,O75962,Q9H0H5,P42166
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
156,131,289,763,76,172,702,434,207,746,273,757,467
|
156,273,1295,987,172,911,467,207,1439,1397,289,2064,1725,2517,1827,1940,76,1223,744,746,2119,1499,2522,434,131,969,757,1664,1282,2800,763,702
|
1.5362117181364128,1.1093425443192109,0.0916230653837448,0.2729362763877655,1.4775738794299105,0.32349580032456454,0.7786741122076469,1.3174933512024687,0.011755338385683791,0.038526658332115674,1.0665769311873845,-0.35062453129738713,-0.15209923198018688,-0.6492423972397605,-0.20798764245173287,-0.2645349940023304,2.2376915434747073,0.14413493056950505,0.47202132781882844,0.47202132781882844,-0.37966711166030426,-0.015166862701093613,-0.6492423972397605,0.8241310428665671,1.7078061122023387,0.298283282312465,0.47202132781882844,-0.09685523182921355,0.11795129526109982,-0.9675239012000673,0.47202132781882844,0.5205132181705904
| 3,120
|
Aplasia hypoplasia involving bones of the thorax
| 13
| 34
| 2.183738
| 0.028981
|
Q7RTS9,P02545,O75431,Q8TAA9,O60826,Q9UHX1,Q96L58,Q15427,P98175,P39019,O75844,Q14999,Q8NC56
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,376,464,131,331,397,166,490,426,425,123,430,287
|
2454,1528,331,2014,464,123,376,1209,1389,2573,2254,425,1160,3059,2106,426,1219,2583,746,1552,430,490,1687,2664,2072,32,287,2073,131,528,166,1463,2888,397
|
-0.6185351182463072,-0.042241579625993585,0.9579237536502591,-0.3217563066408477,0.7786741122076469,1.763620063558507,0.8915034664671595,0.14413493056950505,0.038526658332115674,-0.7112482098625537,-0.46786141367036915,0.8241310428665671,0.17017548246536693,-1.9076504275094626,-0.37966711166030426,0.8241310428665671,0.14413493056950505,-0.7112482098625537,0.47202132781882844,-0.042241579625993585,0.8241310428665671,0.75578003326324,-0.12439757025387724,-0.8057719361207141,-0.35062453129738713,3.210375491197299,1.0880085580638097,-0.35062453129738713,1.7078061122023387,0.709655477037906,1.516747891198495,0.011755338385683791,-1.1348420125464262,0.8691530690352253
| 3,120
|
Golgi stack
| 13
| 31
| 2.176066
| 0.02955
|
Q8NBN3,O95249,Q96L58,Q10471,Q96JB2,Q10713,Q15363,P51572,Q8TBA6,O60763,Q14789,Q10472,Q9UNZ2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
35,253,166,351,122,105,636,862,542,767,776,471,624
|
767,253,2507,1071,2023,1303,862,1086,2108,1786,1126,863,351,471,105,1220,776,2117,636,1740,35,542,1888,122,166,1660,2080,1368,1104,1852,624
|
0.4475879086837396,1.1517209730784248,-0.6492423972397605,0.22183326505174678,-0.3217563066408477,0.0916230653837448,0.37352278495630703,0.22183326505174678,-0.37966711166030426,-0.17996198897025922,0.19607443889255075,0.37352278495630703,0.9358878616746352,0.7786741122076469,1.9092431533941194,0.14413493056950505,0.4475879086837396,-0.37966711166030426,0.5685132566383815,-0.15209923198018688,3.156189494592303,0.6864228881683501,-0.23617802356071166,1.7820760211495976,1.516747891198495,-0.09685523182921355,-0.35062453129738713,0.06514870608694326,0.22183326505174678,-0.20798764245173287,0.5923317961811347
| 3,120
|
Abnormal peripheral nervous system physiology
| 13
| 48
| 2.171566
| 0.029888
|
P04792,P02545,O95721,Q99720,P07196,P20700,O60313,Q9GZY8,Q9NQZ5,O95831,Q9NR77,O95140,Q92734
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,376,69,6,103,288,389,510,181,86,126,332,386
|
802,979,2804,1768,982,389,332,69,86,376,128,103,1917,2460,288,2513,1487,861,2630,1781,1724,2064,1592,1215,2398,2976,2542,2758,1733,2349,2548,1000,1094,2358,2232,934,386,2794,6,510,181,126,1664,2372,2050,622,949,533
|
0.42302785571210444,0.2729362763877655,-1.000530653277979,-0.17996198897025922,0.2729362763877655,0.8691530690352253,0.9579237536502591,2.3692468623114746,2.119398055387944,0.8915034664671595,1.7264856813353782,1.9271271193823978,-0.2645349940023304,-0.6185351182463072,1.0665769311873845,-0.6492423972397605,-0.015166862701093613,0.37352278495630703,-0.7740586736982547,-0.17996198897025922,-0.15209923198018688,-0.35062453129738713,-0.0694704733838678,0.14413493056950505,-0.5576999615504026,-1.379165978216167,-0.6801459566044995,-0.9347396848564197,-0.15209923198018688,-0.5275674680675104,-0.6801459566044995,0.2729362763877655,0.22183326505174678,-0.5275674680675104,-0.4382834749199662,0.32349580032456454,0.8915034664671595,-0.9675239012000673,4.647892361308431,0.7327741710393836,1.4578623634759529,1.763620063558507,-0.09685523182921355,-0.5275674680675104,-0.3217563066408477,0.5923317961811347,0.32349580032456454,0.709655477037906
| 3,120
|
Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]
| 57
| 130
| 2.164563
| 0.030421
|
O75821,Q9UHX1,Q8WXF1,P38159,O60506,P52756,P62995,P84103,P23588,Q92804,Q9BWF3,O14979,Q08170,P55795,Q86V81,Q07955,O43390,Q9Y6M1,Q9NWH9,Q9UKM9,P09012,P98179,P98175,Q9Y580,O75494,Q8WUA2,P31942,P51991,Q13247,P33240,Q96PK6,Q15056,P22626,P07910,Q99729,Q14011,Q86U42,P78332,Q16629,Q14103,Q13151,Q9Y2U8,Q15427,Q13243,Q15233,Q13242,P08579,Q8N684,P19338,Q13595,P26368,Q12849,P35637,Q9GZT3,P23246,Q9UKV3,Q01085
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
628,397,527,140,517,263,265,521,276,153,547,272,774,404,286,293,399,826,443,698,552,48,426,315,803,573,424,681,570,566,847,323,321,205,342,81,337,712,227,615,612,763,490,503,747,234,485,504,241,242,737,742,248,647,496,650,499
|
1148,1811,272,1965,1065,399,2248,517,803,628,1863,1480,1296,988,205,485,1338,552,1339,1819,3039,2459,241,321,496,276,737,1033,1871,424,1252,566,248,140,1977,861,920,681,1122,957,263,404,1305,2032,265,712,521,426,48,2169,499,923,3098,293,774,742,1221,612,234,503,570,1990,2109,242,81,615,2036,1832,2266,1879,323,747,1452,1944,490,962,227,1353,3067,1093,2357,337,286,2123,1601,2271,2856,504,2274,573,1182,2793,527,1752,153,2873,1011,1566,1053,847,1320,1463,342,1274,547,2593,1573,2668,647,971,1146,1899,853,443,1806,1025,1026,1473,397,1328,698,650,1854,763,1856,2772,2376,315,2086,826
|
0.17017548246536693,-0.20798764245173287,1.1093425443192109,-0.29306044672954845,0.22183326505174678,0.8466959209611702,-0.46786141367036915,0.709655477037906,0.42302785571210444,0.5685132566383815,-0.23617802356071166,-0.015166862701093613,0.0916230653837448,0.2729362763877655,1.3174933512024687,0.75578003326324,0.06514870608694326,0.6630753264781283,0.06514870608694326,-0.20798764245173287,-1.712329994309814,-0.6185351182463072,1.2145771446757452,0.979856683830239,0.7327741710393836,1.1093425443192109,0.47202132781882844,0.24745340385816628,-0.23617802356071166,0.8241310428665671,0.11795129526109982,0.6396116988763457,1.172767077784285,1.6323249879473072,-0.29306044672954845,0.37352278495630703,0.32349580032456454,0.5205132181705904,0.19607443889255075,0.298283282312465,1.1305797371850148,0.8466959209611702,0.0916230653837448,-0.3217563066408477,1.1305797371850148,0.4963293559988893,0.709655477037906,0.8241310428665671,2.801929332566857,-0.4088860728488319,0.7327741710393836,0.32349580032456454,-2.776256557108311,1.0665769311873845,0.4475879086837396,0.47202132781882844,0.14413493056950505,0.5923317961811347,1.2353427068536198,0.7327741710393836,0.6396116988763457,-0.29306044672954845,-0.37966711166030426,1.2145771446757452,2.2042035774756688,0.5923317961811347,-0.3217563066408477,-0.20798764245173287,-0.46786141367036915,-0.23617802356071166,0.979856683830239,0.47202132781882844,0.011755338385683791,-0.2645349940023304,0.75578003326324,0.298283282312465,1.256016338166523,0.06514870608694326,-1.9879928242428384,0.22183326505174678,-0.5275674680675104,0.9579237536502591,1.0880085580638097,-0.37966711166030426,-0.0694704733838678,-0.46786141367036915,-1.0672234487170145,0.7327741710393836,-0.46786141367036915,0.6396116988763457,0.17017548246536693,-0.9675239012000673,0.709655477037906,-0.15209923198018688,1.555594300107399,-1.1009154766800557,0.2729362763877655,-0.042241579625993585,0.24745340385816628,0.39833990773856,0.0916230653837448,0.011755338385683791,0.9579237536502591,0.11795129526109982,0.6864228881683501,-0.7112482098625537,-0.042241579625993585,-0.8057719361207141,0.5685132566383815,0.298283282312465,0.19607443889255075,-0.23617802356071166,0.39833990773856,0.8241310428665671,-0.17996198897025922,0.2729362763877655,0.2729362763877655,0.011755338385683791,0.8691530690352253,0.0916230653837448,0.5205132181705904,0.5685132566383815,-0.20798764245173287,0.47202132781882844,-0.20798764245173287,-0.9347396848564197,-0.5275674680675104,1.023417311456126,-0.35062453129738713,0.42302785571210444
| 3,120
|
Genu valgum
| 8
| 33
| 2.16445
| 0.03043
|
Q7RTS9,Q96L58,Q15056,Q9NX62,Q7LGA3,P08236,P16278,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,166,323,137,19,247,283,126
|
2423,2013,464,247,2829,283,1916,2573,2938,2388,2389,1302,1120,998,684,1786,2916,1219,1738,323,1263,19,32,813,166,2000,126,344,137,2669,1371,2134,1286
|
-0.5880217491572218,-0.3217563066408477,0.7786741122076469,1.172767077784285,-1.0337628479999912,1.0880085580638097,-0.2645349940023304,-0.7112482098625537,-1.2729570159514279,-0.5576999615504026,-0.5576999615504026,0.0916230653837448,0.19607443889255075,0.2729362763877655,0.5205132181705904,-0.17996198897025922,-1.2034112370325538,0.14413493056950505,-0.15209923198018688,0.979856683830239,0.11795129526109982,3.9302356800799503,3.210375491197299,0.42302785571210444,1.516747891198495,-0.29306044672954845,1.763620063558507,0.9579237536502591,1.651310887354022,-0.8057719361207141,0.06514870608694326,-0.37966711166030426,0.11795129526109982
| 3,120
|
Presynaptic active zone
| 7
| 15
| 2.15464
| 0.03119
|
P20020,Q8IUD2,P41440,Q13136,O60716,Q07021,Q99623
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
377,783,73,523,675,408,259
|
675,878,1590,377,1777,1391,1642,73,1491,408,1169,523,1942,783,259
|
0.5205132181705904,0.3485751885508132,-0.0694704733838678,0.8915034664671595,-0.17996198897025922,0.038526658332115674,-0.09685523182921355,2.3039419144770994,-0.015166862701093613,0.8466959209611702,0.17017548246536693,0.709655477037906,-0.2645349940023304,0.4475879086837396,1.1517209730784248
| 3,120
|
G protein coupled receptor signaling pathway
| 15
| 40
| 2.151444
| 0.031441
|
Q14344,Q8NCG7,Q99720,Q9Y4G8,Q96SB3,Q9NWH9,P42892,P11717,Q8TEY7,P04083,P35232,P04899,Q9BYT8,P16949,O14908
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
489,557,6,168,696,443,43,233,142,731,519,580,245,275,579
|
2775,1149,579,1625,1586,1070,731,580,1634,1912,233,1075,275,2573,1777,2257,832,519,43,2753,2576,1724,2517,1546,739,1445,1090,1170,489,2549,557,142,696,6,245,443,2372,1327,949,168
|
-0.9675239012000673,0.17017548246536693,0.616030896851247,-0.09685523182921355,-0.0694704733838678,0.22183326505174678,0.47202132781882844,0.616030896851247,-0.09685523182921355,-0.2645349940023304,1.2353427068536198,0.22183326505174678,1.1093425443192109,-0.7112482098625537,-0.17996198897025922,-0.46786141367036915,0.39833990773856,0.709655477037906,2.875037373385399,-0.9347396848564197,-0.7112482098625537,-0.15209923198018688,-0.6492423972397605,-0.042241579625993585,0.47202132781882844,0.011755338385683791,0.22183326505174678,0.17017548246536693,0.75578003326324,-0.6801459566044995,0.6630753264781283,1.6132609997025542,0.5205132181705904,4.647892361308431,1.193718866633161,0.8241310428665671,-0.5275674680675104,0.0916230653837448,0.32349580032456454,1.516747891198495
| 3,120
|
Distal lower limb muscle weakness
| 8
| 18
| 2.145593
| 0.031905
|
P04792,P02545,Q9Y6X9,P07196,P06753,P00846,O95140,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,376,533,103,450,52,332,126
|
579,332,52,376,128,450,103,1917,1487,2706,2398,2758,1992,1001,1558,1050,126,533
|
0.616030896851247,0.9579237536502591,2.7276227820437797,0.8915034664671595,1.7264856813353782,0.8014574420423553,1.9271271193823978,-0.2645349940023304,-0.015166862701093613,-0.8698275055005745,-0.5576999615504026,-0.9347396848564197,-0.29306044672954845,0.2729362763877655,-0.042241579625993585,0.24745340385816628,1.763620063558507,0.709655477037906
| 3,120
|
Protein transmembrane transport
| 8
| 24
| 2.143052
| 0.032109
|
Q15388,O75298,O14925,O60830,O95831,Q9NS69,Q15629,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
294,110,171,176,86,261,383,183
|
171,1030,2845,176,110,1906,1629,86,1631,1715,183,994,2941,1930,2633,428,294,383,841,1095,1570,972,261,875
|
1.4775738794299105,0.24745340385816628,-1.0672234487170145,1.4578623634759529,1.8551713497297029,-0.2645349940023304,-0.09685523182921355,2.119398055387944,-0.09685523182921355,-0.15209923198018688,1.4380669400587471,0.2729362763877655,-1.2729570159514279,-0.2645349940023304,-0.7740586736982547,0.8241310428665671,1.0665769311873845,0.8915034664671595,0.39833990773856,0.22183326505174678,-0.042241579625993585,0.298283282312465,1.1517209730784248,0.37352278495630703
| 3,120
|
Talipes equinovarus
| 21
| 80
| 2.139024
| 0.032434
|
P04792,Q15392,Q8TAA9,Q9Y487,Q8NI60,Q8NCH0,Q7RTS9,Q96AY3,Q96L58,Q15907,P98175,Q8TD16,P61978,P06753,P36543,P21964,Q15427,O96028,P08236,Q9NR77,Q9HD42
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,130,131,150,413,161,32,436,166,49,426,188,322,450,213,466,490,347,247,126,260
|
2204,2454,2331,2845,982,627,2014,2892,1588,2568,909,347,128,450,247,1675,1209,1917,2573,466,2155,213,1645,1875,2847,2216,1592,958,2470,2030,322,426,684,1548,500,1733,1942,1790,130,490,49,1455,663,1997,930,32,2183,161,2073,2641,413,131,2232,188,2642,751,1185,591,436,166,2000,1319,2888,970,1322,2282,793,2766,260,126,1192,1193,1371,1194,1421,949,1110,150,2086,2934
|
-0.4382834749199662,-0.6185351182463072,-0.5275674680675104,-1.0672234487170145,0.2729362763877655,0.5685132566383815,-0.3217563066408477,-1.169006197935009,-0.0694704733838678,-0.7112482098625537,0.32349580032456454,0.9358878616746352,1.7264856813353782,0.8014574420423553,1.172767077784285,-0.12439757025387724,0.14413493056950505,-0.2645349940023304,-0.7112482098625537,0.7786741122076469,-0.4088860728488319,1.297090899466863,-0.09685523182921355,-0.23617802356071166,-1.0672234487170145,-0.4382834749199662,-0.0694704733838678,0.298283282312465,-0.6185351182463072,-0.3217563066408477,0.979856683830239,0.8241310428665671,0.5205132181705904,-0.042241579625993585,0.7327741710393836,-0.15209923198018688,-0.2645349940023304,-0.17996198897025922,1.7078061122023387,0.75578003326324,2.801929332566857,0.011755338385683791,0.5445741216866079,-0.29306044672954845,0.32349580032456454,3.210375491197299,-0.4088860728488319,1.5362117181364128,-0.35062453129738713,-0.7740586736982547,0.8466959209611702,1.7078061122023387,-0.4382834749199662,1.4380669400587471,-0.7740586736982547,0.47202132781882844,0.17017548246536693,0.616030896851247,0.8241310428665671,1.516747891198495,-0.29306044672954845,0.0916230653837448,-1.1348420125464262,0.298283282312465,0.0916230653837448,-0.46786141367036915,0.4475879086837396,-0.9347396848564197,1.1517209730784248,1.763620063558507,0.17017548246536693,0.17017548246536693,0.06514870608694326,0.17017548246536693,0.038526658332115674,0.32349580032456454,0.22183326505174678,1.5748962832288216,-0.35062453129738713,-1.238060398252917
| 3,120
|
Foot dorsiflexor weakness
| 10
| 33
| 2.134103
| 0.032834
|
P04792,P02545,Q99720,P07196,P06753,O43819,Q9BQT8,O95140,Q13501,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,376,6,103,450,239,480,332,382,126
|
855,579,979,2804,239,332,376,128,1249,450,103,1871,2680,1781,2064,1215,2030,2398,1785,382,2785,1992,746,2587,1653,1556,2232,1800,6,480,126,2134,533
|
0.37352278495630703,0.616030896851247,0.2729362763877655,-1.000530653277979,1.2145771446757452,0.9579237536502591,0.8915034664671595,1.7264856813353782,0.11795129526109982,0.8014574420423553,1.9271271193823978,-0.23617802356071166,-0.8376939983695894,-0.17996198897025922,-0.35062453129738713,0.14413493056950505,-0.3217563066408477,-0.5576999615504026,-0.17996198897025922,0.8915034664671595,-0.9675239012000673,-0.29306044672954845,0.47202132781882844,-0.7112482098625537,-0.09685523182921355,-0.042241579625993585,-0.4382834749199662,-0.17996198897025922,4.647892361308431,0.7786741122076469,1.763620063558507,-0.37966711166030426,0.709655477037906
| 3,120
|
Transporter activity
| 44
| 167
| 2.114573
| 0.034466
|
P20020,O43772,Q13423,O75947,O14548,Q9Y487,Q8IXU6,Q8WTV0,P21796,Q15388,P13073,O14925,O60830,Q9P0J0,P00846,Q6N075,P36542,Q9UDW1,Q8TDW0,P06576,Q9H2D1,Q9NZD2,P30825,P17900,P08183,Q07820,Q14847,Q9HD20,P41440,P45880,P16615,Q9Y277,Q7KZN9,P36543,P24539,O15118,Q70HW3,Q93050,P20674,O75964,Q9BXB4,Q9NS69,Q8N4V1,O96000
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
377,1,133,252,388,150,22,28,160,294,42,171,176,313,52,54,305,56,189,422,61,320,63,190,64,428,429,327,73,454,452,79,335,213,94,95,97,99,349,114,387,261,250,124
|
2802,3109,2654,1522,388,1149,171,95,3070,1768,1,1066,2602,176,705,2909,2294,2505,1152,1587,252,114,1629,654,1711,984,909,2425,550,124,1631,604,52,3087,1773,1249,910,2147,422,2703,828,1482,64,912,1774,2023,2383,1676,2808,2536,42,452,190,2152,377,349,1389,859,160,2574,1777,94,919,2212,1342,2628,63,2513,1159,305,213,537,1645,73,454,2575,955,1821,994,2833,1876,2927,681,1165,2706,2397,808,2849,883,2163,2633,3065,2108,2441,2899,1594,1219,428,133,960,1350,429,2549,294,1224,716,1002,779,54,1308,1689,1882,1136,2552,97,335,22,250,2183,1007,526,2318,1180,2075,189,28,1183,1052,99,2954,575,723,594,1101,1954,1366,480,901,387,1102,2047,2919,61,758,1661,820,2766,327,261,852,1059,320,313,797,56,875,1763,602,1194,1283,79,1331,150,2719,3014,1196,764
|
-1.000530653277979,-3.4883531035688655,-0.8057719361207141,-0.042241579625993585,0.8691530690352253,0.17017548246536693,1.4775738794299105,2.0329969890041335,-2.0696602571110043,-0.17996198897025922,5.144282894154371,0.22183326505174678,-0.7425516146318213,1.4578623634759529,0.4963293559988893,-1.2034112370325538,-0.4976220214613302,-0.6492423972397605,0.17017548246536693,-0.0694704733838678,1.1517209730784248,1.818768282448762,-0.09685523182921355,0.5445741216866079,-0.15209923198018688,0.2729362763877655,0.32349580032456454,-0.5880217491572218,0.6630753264781283,1.763620063558507,-0.09685523182921355,0.5923317961811347,2.7276227820437797,-2.499432291736275,-0.17996198897025922,0.11795129526109982,0.32349580032456454,-0.4088860728488319,0.8241310428665671,-0.8698275055005745,0.39833990773856,-0.015166862701093613,2.401552801979837,0.32349580032456454,-0.17996198897025922,-0.3217563066408477,-0.5576999615504026,-0.12439757025387724,-1.000530653277979,-0.6801459566044995,2.875037373385399,0.8014574420423553,1.4181869234230973,-0.4088860728488319,0.8915034664671595,0.9358878616746352,0.038526658332115674,0.37352278495630703,1.5362117181364128,-0.7112482098625537,-0.17996198897025922,2.050407604865225,0.32349580032456454,-0.4382834749199662,0.06514870608694326,-0.7740586736982547,2.449587253406975,-0.6492423972397605,0.17017548246536693,1.023417311456126,1.297090899466863,0.6864228881683501,-0.09685523182921355,2.3039419144770994,0.8014574420423553,-0.7112482098625537,0.298283282312465,-0.20798764245173287,0.2729362763877655,-1.0337628479999912,-0.23617802356071166,-1.238060398252917,0.5205132181705904,0.17017548246536693,-0.8698275055005745,-0.5576999615504026,0.42302785571210444,-1.0672234487170145,0.3485751885508132,-0.4088860728488319,-0.7740586736982547,-1.947658572174278,-0.37966711166030426,-0.5880217491572218,-1.169006197935009,-0.0694704733838678,0.14413493056950505,0.8241310428665671,1.689050850473479,0.298283282312465,0.06514870608694326,0.8241310428665671,-0.6801459566044995,1.0665769311873845,0.14413493056950505,0.4963293559988893,0.2729362763877655,0.4475879086837396,2.6975560940099816,0.0916230653837448,-0.12439757025387724,-0.23617802356071166,0.19607443889255075,-0.6801459566044995,2.0155202250676534,0.9579237536502591,3.74297377627154,1.172767077784285,-0.4088860728488319,0.2729362763877655,0.709655477037906,-0.4976220214613302,0.17017548246536693,-0.35062453129738713,1.4380669400587471,3.369120265484028,0.17017548246536693,0.24745340385816628,1.9979768307458792,-1.3081044921965708,0.6396116988763457,0.4963293559988893,0.616030896851247,0.22183326505174678,-0.2645349940023304,0.06514870608694326,0.7786741122076469,0.3485751885508132,0.8915034664671595,0.22183326505174678,-0.3217563066408477,-1.2034112370325538,2.4813316430188412,0.47202132781882844,-0.09685523182921355,0.42302785571210444,-0.9347396848564197,0.979856683830239,1.1517209730784248,0.39833990773856,0.24745340385816628,1.001687568375461,1.023417311456126,0.4475879086837396,2.575259739826172,0.37352278495630703,-0.15209923198018688,0.616030896851247,0.17017548246536693,0.11795129526109982,2.2209781437623697,0.0916230653837448,1.5748962832288216,-0.8698275055005745,-1.5244569016571512,0.17017548246536693,0.47202132781882844
| 3,120
|
Limitation of joint mobility
| 36
| 98
| 2.110053
| 0.034854
|
P02545,O60568,Q8TAA9,P23786,P54802,O14974,Q13045,Q7LGA3,O14979,P16278,Q8WXH0,Q7RTS9,Q96AX1,Q96AY3,Q96L58,P50402,Q9H6K4,O94905,P48735,Q8TD16,O76024,Q92917,Q15056,P06753,P37268,Q8WVM7,P25054,O95140,P51648,Q9UQE7,O75431,Q15427,P15586,P08236,O75844,Q03001
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,627,131,379,264,513,522,19,272,283,543,32,693,436,166,289,174,677,306,188,565,720,323,450,709,209,708,332,91,762,464,490,111,247,123,500
|
2501,2204,2454,513,272,2331,2423,2503,627,1905,2673,2014,464,2892,2970,123,1202,565,677,332,1154,376,450,247,1634,111,283,1209,2573,2254,379,708,2155,2434,1642,2388,709,1487,3059,306,289,1121,91,264,2030,2398,998,1786,1548,500,1219,1446,2583,1733,2867,522,2785,1992,1450,1738,1790,2690,323,490,2664,19,32,2590,2183,2641,131,934,188,2642,209,543,720,1317,2555,1185,693,436,166,2000,1463,1609,1054,970,174,2766,943,2669,1193,762,1421,763,1286,2907
|
-0.6492423972397605,-0.4382834749199662,-0.6185351182463072,0.709655477037906,1.1093425443192109,-0.5275674680675104,-0.5880217491572218,-0.6492423972397605,0.5685132566383815,-0.2645349940023304,-0.8376939983695894,-0.3217563066408477,0.7786741122076469,-1.169006197935009,-1.379165978216167,1.763620063558507,0.14413493056950505,0.6396116988763457,0.5205132181705904,0.9579237536502591,0.17017548246536693,0.8915034664671595,0.8014574420423553,1.172767077784285,-0.09685523182921355,1.8370056925799199,1.0880085580638097,0.14413493056950505,-0.7112482098625537,-0.46786141367036915,0.8915034664671595,0.4963293559988893,-0.4088860728488319,-0.5880217491572218,-0.09685523182921355,-0.5576999615504026,0.4963293559988893,-0.015166862701093613,-1.9076504275094626,1.023417311456126,1.0665769311873845,0.19607443889255075,2.0677525498216016,1.1305797371850148,-0.3217563066408477,-0.5576999615504026,0.2729362763877655,-0.17996198897025922,-0.042241579625993585,0.7327741710393836,0.14413493056950505,0.011755338385683791,-0.7112482098625537,-0.15209923198018688,-1.1009154766800557,0.709655477037906,-0.9675239012000673,-0.29306044672954845,0.011755338385683791,-0.15209923198018688,-0.17996198897025922,-0.8376939983695894,0.979856683830239,0.75578003326324,-0.8057719361207141,3.9302356800799503,3.210375491197299,-0.7112482098625537,-0.4088860728488319,-0.7740586736982547,1.7078061122023387,0.32349580032456454,1.4380669400587471,-0.7740586736982547,1.3174933512024687,0.6864228881683501,0.4963293559988893,0.0916230653837448,-0.6801459566044995,0.17017548246536693,0.5205132181705904,0.8241310428665671,1.516747891198495,-0.29306044672954845,0.011755338385683791,-0.0694704733838678,0.24745340385816628,0.298283282312465,1.4775738794299105,-0.9347396848564197,0.32349580032456454,-0.8057719361207141,0.17017548246536693,0.47202132781882844,0.038526658332115674,0.47202132781882844,0.11795129526109982,-1.169006197935009
| 3,120
|
Atpase coupled transmembrane transporter activity
| 6
| 20
| 2.109173
| 0.03493
|
P20020,P08183,Q15388,Q9HD20,P06576,P36543
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
377,64,294,327,422,213
|
705,1249,910,422,64,452,377,1389,859,1777,2212,1159,213,1645,2163,2108,1219,294,327,1763
|
0.4963293559988893,0.11795129526109982,0.32349580032456454,0.8241310428665671,2.401552801979837,0.8014574420423553,0.8915034664671595,0.038526658332115674,0.37352278495630703,-0.17996198897025922,-0.4382834749199662,0.17017548246536693,1.297090899466863,-0.09685523182921355,-0.4088860728488319,-0.37966711166030426,0.14413493056950505,1.0665769311873845,0.979856683830239,-0.15209923198018688
| 3,120
|
Outer membrane
| 29
| 91
| 2.107575
| 0.035068
|
Q99720,O60313,O00264,P57105,P21796,Q8WXH0,Q5VT66,Q15388,P50402,Q9NX63,Q99536,Q9NQZ5,Q07820,Q96TC7,Q9NZ45,Q8N4H5,Q13505,P45880,Q9Y277,O43169,Q5XKP0,Q9BWH2,O95140,Q53H12,O75431,Q16891,Q9GZY8,Q9NS69,Q99623
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
6,389,262,405,160,543,541,294,289,312,576,181,428,326,200,70,76,454,79,80,208,216,332,586,464,355,510,261,259
|
2291,262,1197,3116,80,389,1904,1627,464,1629,332,1481,1631,2674,2911,1913,770,1917,160,2628,1254,1542,2466,1161,454,289,1082,1680,2438,405,3074,428,999,76,1001,294,1792,355,586,541,208,1881,1745,587,2040,964,1458,1797,813,1232,70,2590,2183,2641,2232,1183,543,1406,1889,2592,2794,326,576,259,6,1755,2045,901,216,872,510,1805,2651,1758,181,261,3000,1703,821,1280,2718,312,2957,200,2372,2597,1282,79,1027,702,2500
|
-0.4976220214613302,1.1305797371850148,0.14413493056950505,-4.125938690516134,2.2042035774756688,0.8691530690352253,-0.2645349940023304,-0.09685523182921355,0.7786741122076469,-0.09685523182921355,0.9579237536502591,-0.015166862701093613,-0.09685523182921355,-0.8376939983695894,-1.2034112370325538,-0.2645349940023304,0.4475879086837396,-0.2645349940023304,1.5362117181364128,-0.7740586736982547,0.11795129526109982,-0.042241579625993585,-0.6185351182463072,0.17017548246536693,0.8014574420423553,1.0665769311873845,0.22183326505174678,-0.12439757025387724,-0.5880217491572218,0.8466959209611702,-2.1110040441905302,0.8241310428665671,0.2729362763877655,2.2376915434747073,0.2729362763877655,1.0665769311873845,-0.17996198897025922,0.9358878616746352,0.616030896851247,0.6864228881683501,1.3174933512024687,-0.23617802356071166,-0.15209923198018688,0.616030896851247,-0.3217563066408477,0.298283282312465,0.011755338385683791,-0.17996198897025922,0.42302785571210444,0.14413493056950505,2.3692468623114746,-0.7112482098625537,-0.4088860728488319,-0.7740586736982547,-0.4382834749199662,0.17017548246536693,0.6864228881683501,0.038526658332115674,-0.23617802356071166,-0.7112482098625537,-0.9675239012000673,0.979856683830239,0.6396116988763457,1.1517209730784248,4.647892361308431,-0.15209923198018688,-0.3217563066408477,0.3485751885508132,1.297090899466863,0.37352278495630703,0.7327741710393836,-0.17996198897025922,-0.7740586736982547,-0.15209923198018688,1.4578623634759529,1.1517209730784248,-1.451273498282404,-0.12439757025387724,0.42302785571210444,0.11795129526109982,-0.8698275055005745,1.023417311456126,-1.3081044921965708,1.3580323311839413,-0.5275674680675104,-0.7112482098625537,0.11795129526109982,2.2209781437623697,0.2729362763877655,0.5205132181705904,-0.6185351182463072
| 3,120
|
Abnormal femoral neck head morphology
| 15
| 45
| 2.103208
| 0.035448
|
Q7RTS9,P02545,O60568,O75431,Q96AY3,Q96L58,Q96HY6,O75718,Q96A33,Q7LGA3,Q9Y487,O95831,P04066,P16278,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,376,627,464,436,166,528,346,591,19,150,86,282,283,123
|
2501,627,2014,464,2892,346,123,86,376,282,283,2573,2433,2155,1542,2753,1304,2159,808,1930,1219,746,1738,1552,2268,663,2072,19,32,2523,591,436,528,166,1319,3012,1058,793,2241,2595,1371,1421,1374,150,2086
|
-0.6492423972397605,0.5685132566383815,-0.3217563066408477,0.7786741122076469,-1.169006197935009,0.9358878616746352,1.763620063558507,2.119398055387944,0.8915034664671595,1.0880085580638097,1.0880085580638097,-0.7112482098625537,-0.5880217491572218,-0.4088860728488319,-0.042241579625993585,-0.9347396848564197,0.0916230653837448,-0.4088860728488319,0.42302785571210444,-0.2645349940023304,0.14413493056950505,0.47202132781882844,-0.15209923198018688,-0.042241579625993585,-0.46786141367036915,0.5445741216866079,-0.35062453129738713,3.9302356800799503,3.210375491197299,-0.6492423972397605,0.616030896851247,0.8241310428665671,0.709655477037906,1.516747891198495,0.0916230653837448,-1.5244569016571512,0.24745340385816628,0.4475879086837396,-0.4382834749199662,-0.7112482098625537,0.06514870608694326,0.038526658332115674,0.06514870608694326,1.5748962832288216,-0.35062453129738713
| 3,120
|
Subcutaneous nodule
| 6
| 19
| 2.099386
| 0.035783
|
Q13510,Q9NSE4,P06280,Q9NZ08,P48735,P35637
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
44,344,232,145,306,248
|
1202,1154,232,1157,378,708,1642,248,306,2214,2608,1084,1786,2583,44,778,344,145,763
|
0.14413493056950505,0.17017548246536693,1.2353427068536198,0.17017548246536693,0.8915034664671595,0.4963293559988893,-0.09685523182921355,1.172767077784285,1.023417311456126,-0.4382834749199662,-0.7425516146318213,0.22183326505174678,-0.17996198897025922,-0.7112482098625537,2.860509873296997,0.4475879086837396,0.9579237536502591,1.5941183060567525,0.47202132781882844
| 3,120
|
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