term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Constriction of peripheral visual field | 7 | 21 | 2.126078 | 0.033497 | P50542,P00846,Q8WWY3,O43837,Q9H061,O60313,P40855 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 65,99,236,196,78,428,562 | 196,578,428,2433,99,2004,2660,2086,2514,1755,2089,562,1205,65,1243,1017,2306,926,236,78,1988 | 1.4508080180236562,0.7459093931850885,0.9507440976385911,-0.48658469438810514,1.9500014918186808,-0.23501011839942096,-0.6239246546713384,-0.2807305656763728,-0.5323553332283967,-0.09790213373324297,-0.2807305656763728,0.7686765614043631,0.22171244811574498,2.2672389993833404,0.19889667227848584,0.35856331139810654,-0.... | 3,376 |
Proteasome component (PCI) domain [IPR000717] | 12 | 20 | 2.122809 | 0.03377 | P48556,Q9UBW8,Q99627,Q9UNM6,Q7L2H7,Q9Y262,Q15008,Q9BT78,P60228,O00231,P61201,Q9UNS2 | Sequence | InterPro Domain | interpro_domain | 157,799,173,276,505,637,895,216,148,340,377,881 | 340,1433,1307,157,148,377,1081,923,895,3064,505,2410,173,216,1300,2233,799,276,881,637 | 1.1326894914941044,0.08478612682723895,0.15325880693776223,1.5870359038920763,1.609734331636171,1.0644741097862722,0.31295465596021727,0.4269608745762918,0.4497559749392965,-1.082349393180815,0.8597257693570096,-0.4637028527189056,1.5416337356516463,1.4280971068172954,0.17607879404889298,-0.3493281113577081,0.540916101... | 3,376 |
Abnormal peripheral nervous system physiology | 17 | 55 | 2.122149 | 0.033825 | P20700,P02545,Q9NR77,Q9GZY8,O95721,O95831,Q9BYI3,O15121,P31930,Q9UBB4,O15269,Q6UWE0,Q8TB36,O60313,O95140,O43681,Q96RL7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 155,218,4,273,444,7,174,352,232,636,514,603,539,428,404,684,92 | 352,514,1232,684,1595,428,1041,404,444,7,218,1201,3268,2086,1754,155,232,1650,1139,1171,860,2249,780,2981,1008,1490,946,2599,2332,691,2900,2878,2401,1497,1617,603,1153,2531,539,2533,3167,905,92,3292,174,273,1665,4,1262,1947,1739,636,1269,2318,3022 | 1.1099529042532705,0.8369663760218362,0.19889667227848584,0.6320440740122428,-0.00654070501984235,0.9507440976385911,0.33576001581343007,0.9962417903147566,0.9279923914863851,4.321881386246311,1.4053843934011567,0.22171244811574498,-1.7258692943152663,-0.2807305656763728,-0.09790213373324297,1.5870359038920763,1.382669... | 3,376 |
Rnd3 gtpase cycle | 7 | 16 | 2.12187 | 0.033849 | P12277,Q07065,Q14254,O43396,Q86UP2,Q9NYL9,Q13464 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,130,131,412,367,544,61 | 412,3170,64,3009,1962,601,130,61,1049,2166,131,367,1848,1784,544,1908 | 0.9734938954710396,-1.311938119790353,2.312532127633527,-0.9905855228656107,-0.21215324764925397,0.7231402673093839,1.700510440366334,2.357818723202082,0.33576001581343007,-0.3264600029423213,1.700510440366334,1.0872144454036603,-0.14359595996140015,-0.09790213373324297,0.8142050472643398,-0.1664461756216075 | 3,376 |
Endosome organization | 16 | 34 | 2.116431 | 0.034308 | O75351,O43633,Q9HD42,Q8IYI6,Q2M389,A5D8V6,Q86VS8,O43752,Q9H9H4,Q9UQN3,Q9H267,Q15075,Q9NP79,Q9BRG1,P53990,Q96ED9 | Processes and pathways | GO Biological process | msigdb_gobp | 596,594,633,653,172,513,368,326,409,704,741,212,679,761,565,260 | 513,2076,594,326,1129,3006,596,2981,565,2297,865,1355,2253,212,172,2211,368,653,2265,1252,260,2106,761,817,741,409,633,679,2421,1226,2281,1907,704,1746 | 0.8369663760218362,-0.2807305656763728,0.7231402673093839,1.1554242122572953,0.2673377183743358,-0.9905855228656107,0.7231402673093839,-0.9447186346692006,0.7686765614043631,-0.3950711452504818,0.4725490417782299,0.13043670441630822,-0.37219848961093516,1.4280971068172954,1.5416337356516463,-0.3493281113577081,1.087214... | 3,376 |
Chaperone mediated protein folding | 23 | 38 | 2.113528 | 0.034556 | Q02790,P50990,Q9H2J4,Q13451,Q99832,P38646,P48723,Q12931,P78371,O00273,P40855,Q9H3U1,P49368,Q15185,O14737,O75190,Q32P28,P40227,P48643,Q9UHD1,O75718,Q99615,Q08752 | Processes and pathways | GO Biological process | msigdb_gobp | 1012,623,798,787,931,919,1046,1176,432,802,562,700,446,843,576,828,478,1107,860,767,239,1160,752 | 802,1304,576,2428,828,239,1562,1797,1867,1753,1314,1603,3163,919,1107,562,860,1046,446,623,1489,1877,1570,432,1012,752,2095,1176,787,843,478,1891,1220,1160,931,798,700,767 | 0.5181290990123865,0.15325880693776223,0.7459093931850885,-0.48658469438810514,0.4953400811340294,1.359953540760634,0.016294229330441935,-0.12074794835789432,-0.1664461756216075,-0.09790213373324297,0.15325880693776223,-0.00654070501984235,-1.288967548658644,0.4269608745762918,0.29014722557938266,0.7686765614043631,0.4... | 3,376 |
Peptide hormone metabolism | 7 | 13 | 2.112553 | 0.034639 | Q8IYI6,Q15005,Q9NV70,Q8TAG9,Q9UPT5,P33176,P67812 | Processes and pathways | Reactome Pathways | msigdb_reactome | 653,386,245,902,384,256,62 | 1191,914,1862,256,2011,62,386,653,902,1220,1818,245,384 | 0.22171244811574498,0.4269608745762918,-0.1664461756216075,1.3145154214917698,-0.23501011839942096,2.335176240038532,1.0417318922140226,0.6775961200071496,0.4497559749392965,0.22171244811574498,-0.12074794835789432,1.359953540760634,1.0644741097862722 | 3,376 |
Peroxisome organization | 6 | 11 | 2.111992 | 0.034687 | P50542,Q9GZY8,O00429,O43933,Q7Z434,P40855 | Processes and pathways | GO Biological process | msigdb_gobp | 65,273,351,578,202,562 | 351,2113,1068,578,727,1872,562,65,202,273,2234 | 1.1099529042532705,-0.30359415686543867,0.31295465596021727,0.7459093931850885,0.5864840833173061,-0.1664461756216075,0.7686765614043631,2.2672389993833404,1.4508080180236562,1.291793624694478,-0.3493281113577081 | 3,376 |
Positive regulation of protein localization | 53 | 134 | 2.108286 | 0.035006 | Q15154,Q9NQC3,Q9GZY8,O75312,P17612,P31751,Q08752,Q12846,P51572,Q99832,P08237,Q01082,Q96C92,P50402,P26038,P15311,Q9H4A6,Q96AC1,Q96HY6,Q96EP0,Q86V21,O94826,Q16822,P78371,P49368,Q9Y5K6,P35580,O14737,Q7Z434,O00410,Q9Y282,Q96QK1,O14777,P62258,O00264,Q92688,Q13277,P17931,P55786,O00429,P48643,Q9UHD1,Q9NV70,Q9C0E2,O95817,P4984... | Processes and pathways | GO Biological process | msigdb_gobp | 755,392,273,885,886,516,752,265,781,931,775,533,426,779,283,292,312,186,311,310,695,806,308,432,446,853,582,576,202,825,612,87,341,90,89,876,475,725,730,351,860,767,245,115,618,364,247,751,250,124,256,623,650 | 2548,1337,89,2284,825,351,3075,576,341,2114,1309,1789,1437,2852,936,885,806,2289,1678,2392,2627,1864,1598,618,2594,3286,2828,1200,775,1073,2471,1712,247,3179,292,1645,886,725,1753,1441,3141,2123,283,2802,2870,1388,516,256,250,582,1442,1107,860,446,751,1281,364,779,623,1489,781,2477,730,2757,90,3347,2730,1445,978,2635,9... | -0.5552441461593581,0.13043670441630822,2.040674250545313,-0.3950711452504818,0.4953400811340294,1.1099529042532705,-1.105296684161769,0.7459093931850885,1.1326894914941044,-0.30359415686543867,0.15325880693776223,-0.12074794835789432,0.08478612682723895,-0.7842622939081015,0.40416373461270877,0.4497559749392965,0.5181... | 3,376 |
Bradykinesia | 6 | 27 | 2.105375 | 0.035259 | P12235,P31930,Q96QK1,P06753,Q6DKK2,Q96RL7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,232,87,146,224,92 | 1309,3006,1236,1862,1796,146,129,1923,232,2754,1963,3195,1490,1840,3124,1449,334,224,1364,1729,87,92,1371,1986,2223,1545,3091 | 0.15325880693776223,-0.9905855228656107,0.19889667227848584,-0.1664461756216075,-0.12074794835789432,1.609734331636171,1.700510440366334,-0.18929860246142455,1.382669872986797,-0.6926264377581445,-0.21215324764925397,-1.3808656899217036,0.061957638500894446,-0.14359595996140015,-1.1741538836336023,0.08478612682723895,1... | 3,376 |
Transmembrane transport | 62 | 228 | 4.276623 | 0.000019 | Q9UBX3,Q13546,O60830,Q13423,P00846,Q9HC07,Q96GC9,Q9UHG3,P12235,O60831,Q6PML9,Q9BSK2,Q6P4A7,Q99497,Q9HD20,Q9UKG1,P50416,Q8N668,P30825,Q9NS69,Q9H2D1,P31751,Q8TB61,Q8WWC4,P31930,O43772,P23786,Q15388,P46939,P61421,Q9Y4W6,Q6YHU6,Q9UI12,P38435,P42858,Q8WTV0,Q8TDW0,Q6KCM7,Q8NE01,Q16762,Q3ZCQ8,O95563,Q70HW3,Q99595,P07384,O4386... | Processes and pathways | GO Biological process | msigdb_gobp | 400,528,4,262,260,139,136,13,143,514,270,18,269,20,151,152,266,285,26,27,29,154,546,286,539,33,34,37,540,293,578,413,447,174,175,50,312,311,440,308,437,302,188,64,68,69,465,321,449,81,211,476,227,228,473,471,357,502,232,109,494,252 | 1427,2171,625,722,2103,3096,898,2104,1216,628,1886,1626,33,1491,69,2666,1556,4,514,946,2239,1690,3097,947,1693,471,1436,3126,698,1891,2029,302,2670,449,1696,494,260,1962,2179,2628,2713,1174,1263,1073,2580,68,1964,2894,252,1265,662,1495,1564,2181,1900,1631,1120,143,1122,2986,1037,1634,2364,1841,1444,827,2716,1123,2247,7... | 0.048211934796472365,-0.2728238448155597,0.5784922208777676,0.49659904864423754,-0.24316559991811548,-1.0118216311731156,0.358643578170959,-0.24316559991811548,0.16225002844017103,0.5784922208777676,-0.15476681385717422,-0.038231613171792155,3.0081206146023467,0.019486354875994212,2.2705322165054698,-0.5439512892731678... | 3,375 |
Mitochondrial transmembrane transport | 18 | 55 | 4.021732 | 0.000058 | Q99595,O43772,P23786,P53007,O60830,Q15388,P00846,Q9BPX6,O95831,Q9H2D1,P12235,Q9BSK2,Q6P4A7,P50416,Q3ZCQ8,Q16762,O95563,Q8WWC4 | Processes and pathways | GO Biological process | msigdb_gobp | 64,33,34,227,4,37,260,465,449,29,143,18,269,266,437,308,302,286 | 1216,1886,33,4,946,947,1693,3126,698,1891,2029,302,449,1696,260,1174,1073,2181,143,1122,700,34,1177,2037,1844,3045,266,227,1086,2681,1509,37,308,437,269,502,775,1814,1869,286,1098,2735,64,465,2848,18,29,1479,2353,1308,938,1750,1485,578,1423 | 0.16225002844017103,-0.15476681385717422,3.0081206146023467,5.415645674566234,0.33082515613705404,0.33082515613705404,-0.0672262509964336,-1.075641485634037,0.5239685462529114,-0.15476681385717422,-0.21360297580762733,1.031106974534266,0.7938228645047847,-0.0672262509964336,1.1349899370587961,0.19054865591249434,0.2468... | 3,375 |
Transporter activity | 56 | 183 | 3.820564 | 0.000133 | Q9UBX3,O60830,Q13423,O15118,O15439,P00846,Q9HC07,O00299,Q96GC9,P49755,P12235,Q6PML9,Q9BSK2,Q9UDW1,Q9HD20,Q6P4A7,P30825,Q9NS69,Q9H2D1,Q9UGP8,Q8TB61,P03886,P31930,O43772,Q9Y5P4,Q15388,Q96BY7,P61421,O43678,Q9UI12,P38435,O43676,Q8WTV0,Q8TDW0,Q6KCM7,Q8NE01,O95563,Q70HW3,P51991,Q99595,Q9H2C2,P41440,Q8N4V1,O75306,P30536,Q96AA... | Functions | GO Molecular function | msigdb_gomf | 400,4,262,627,628,260,139,625,136,636,143,270,18,687,151,269,26,27,29,688,546,31,539,33,694,37,298,293,291,447,174,177,50,312,311,440,302,188,560,64,66,321,81,581,341,618,616,227,228,357,232,250,494,493,252,489 | 1427,625,2103,3022,3096,898,2104,1216,627,489,628,2665,177,291,1167,33,1491,4,946,1690,581,2241,1693,3126,698,1891,493,1172,2029,901,302,1695,1696,494,260,31,1962,2179,2628,1174,1073,2580,1964,2894,252,1265,662,1564,1900,143,1122,2986,1037,2116,2953,1444,827,2716,1123,700,908,1177,2037,1218,2584,341,26,539,3256,1844,25... | 0.048211934796472365,0.5784922208777676,-0.24316559991811548,-0.8851760478860837,-1.0118216311731156,0.358643578170959,-0.24316559991811548,0.16225002844017103,0.5784922208777676,0.7403936172598823,0.5784922208777676,-0.5439512892731678,1.441240326714265,1.057165873125376,0.19054865591249434,3.0081206146023467,0.019486... | 3,375 |
Oxidoreductase activity | 51 | 236 | 3.809608 | 0.000139 | P11310,Q13423,Q8N8N7,Q08257,Q9Y394,P48735,Q15392,Q16836,Q9UHG3,O43819,Q99497,P30519,Q96LJ7,Q9Y6N1,P03886,P31930,O00469,O95881,O15121,P51648,O43678,Q9H7Z7,P14406,O43676,Q00796,P30837,Q6UW02,Q32P28,Q8IXB1,P43304,O15460,O94788,P13674,Q9BY49,O95831,P00390,Q16850,Q96CU9,Q6NUM9,Q9NVH6,P48507,Q3SXM5,O75874,Q9BU89,P51649,Q1580... | Functions | GO Molecular function | msigdb_gomf | 1,262,5,391,535,11,12,15,13,385,20,24,25,427,31,539,280,538,38,410,291,572,49,177,432,55,58,65,72,200,74,75,76,203,449,450,82,86,348,91,342,218,95,358,475,234,356,116,494,493,123 | 1068,697,280,2103,1368,2237,3096,1430,38,1371,628,74,116,1028,1258,2665,177,291,1168,385,2529,2824,859,3268,1690,581,2241,95,2784,75,493,1172,901,449,1768,538,1695,1896,1262,1438,725,450,494,2244,31,661,3237,2712,726,1118,1264,3142,1265,1771,992,993,1326,2114,1564,1772,1,1120,1965,1075,1496,2986,2033,76,2630,1385,49,30... | 0.24689976348114367,0.5239685462529114,1.0831656426328216,-0.24316559991811548,0.07685003800728503,-0.3025770869123972,-1.0118216311731156,0.048211934796472365,2.8043654472386006,0.07685003800728503,0.5784922208777676,2.223153155757611,1.862456329832627,0.27495414250230754,0.13386805297961285,-0.5439512892731678,1.4412... | 3,375 |
Endopeptidase activity | 31 | 60 | 3.692485 | 0.000222 | Q86UV5,Q16740,Q99538,O43847,P14735,Q9Y4E8,Q5JRX3,Q6P179,P49721,Q9Y4W6,Q9P0U3,Q13867,P36776,Q93009,Q8TCT9,Q9BYT8,P28070,Q96K76,P07384,Q99436,P51784,Q9BXS4,P60900,Q96RU2,P28072,O75844,Q9NZ08,P42574,Q93008,P28074,Q4J6C6 | Functions | GO Molecular function | msigdb_gomf | 396,9,137,386,519,425,296,676,40,578,576,46,667,443,564,57,556,63,68,464,322,352,344,620,472,471,103,729,778,238,393 | 2105,3231,386,947,471,68,1327,519,3201,803,2539,1905,556,472,238,1778,910,667,729,1912,2429,2046,2680,40,322,2256,1849,344,1278,999,2899,46,1516,9,393,296,770,676,396,564,2345,1473,2000,778,443,63,620,2464,464,137,1356,1204,352,57,103,576,2410,425,2170,578 | -0.24316559991811548,-1.4653079613874214,0.873480632258922,0.33082515613705404,0.7671410746721091,2.294161378716793,0.10540172980990664,0.713579835070738,-1.334155331699041,0.44164086630862914,-0.45274711809482365,-0.15476681385717422,0.6597506092154378,0.7671410746721091,1.1865840591524877,-0.09631286647900751,0.35864... | 3,375 |
Oxidoreductase | 20 | 169 | 3.69163 | 0.000223 | P11310,Q8N8N7,P48735,Q15392,Q9UHG3,Q16836,P30519,Q96LJ7,O15121,P30837,Q6UW02,Q32P28,Q8IXB1,O15460,O94788,P13674,Q16850,Q96CU9,Q9NVH6,O75874 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 1,5,11,12,13,15,24,25,38,55,58,65,72,74,75,76,82,86,91,95 | 280,1368,2237,1430,38,1371,74,1028,2824,859,3268,1690,581,2241,95,75,449,1768,538,1896,1262,1438,725,450,661,3237,2712,726,1118,3142,992,993,1326,1772,1,1120,1075,1496,2986,76,1385,3009,2830,3331,994,2953,2184,1329,1635,2489,634,828,583,1446,2584,953,2751,2954,1909,24,55,1219,1220,1273,1781,2311,2835,1181,1502,2719,212... | 1.0831656426328216,0.07685003800728503,-0.3025770869123972,0.048211934796472365,2.8043654472386006,0.07685003800728503,2.223153155757611,0.27495414250230754,-0.6668117578076647,0.38638510613707605,-1.7312845351077755,-0.0672262509964336,0.6327337919013768,-0.3025770869123972,2.031985358818018,2.223153155757611,0.793822... | 3,375 |
Intrinsic component of organelle membrane | 43 | 132 | 3.672171 | 0.00024 | O75880,O60830,Q9UH99,Q969X5,Q96S52,P12235,O43819,Q6P4A7,P50416,O15126,Q9Y6N1,Q8TB61,Q15388,P57105,P49069,Q9Y4W6,Q86XL3,O95563,O60499,O95070,Q99595,Q86YN1,Q9BPX6,P04439,Q9HCU5,Q13505,O95140,Q8N4V1,O43752,Q15629,P10321,Q5SNT2,Q9H490,Q9Y282,Q9Y2R0,O75844,Q9NQC3,Q9BWH2,Q03518,Q9UH62,Q9C0E8,O94901,P20337 | Localization | GO Cellular component | msigdb_gocc | 129,4,134,135,273,143,385,269,266,148,427,546,37,541,409,578,44,302,59,301,64,459,465,318,336,334,331,81,209,211,452,347,221,99,363,471,230,359,232,510,377,491,119 | 2526,1427,2237,1216,627,148,1070,3023,2527,209,1491,385,59,4,3097,2297,471,129,2110,1891,491,301,331,1766,302,1696,318,452,143,1444,119,1328,665,1272,910,3010,1912,409,266,2315,2317,1505,541,2895,2257,2438,1509,232,2962,334,1392,1459,3120,2903,2207,1802,37,211,1519,3365,764,2059,768,2062,2391,347,3275,269,1138,2508,321... | -0.45274711809482365,0.048211934796472365,-0.3025770869123972,0.16225002844017103,0.5784922208777676,1.6163849582577512,0.24689976348114367,-0.8851760478860837,-0.45274711809482365,1.2890979463364292,0.019486354875994212,0.873480632258922,2.4117143525221523,5.415645674566234,-1.0118216311731156,-0.33242471265450957,0.7... | 3,375 |
Small molecule metabolic process | 88 | 498 | 3.591371 | 0.000329 | P00813,P11310,Q8N8N7,P48735,Q15392,Q16836,P43490,Q99497,Q4G0N4,Q9H2D1,P49841,P23786,O15121,Q13126,Q8NBZ7,Q13867,Q96EY8,Q8WTV0,Q9BYT8,P30837,Q9H2C2,O43865,P21399,O94788,Q16850,Q9BWD1,Q15120,Q8NI60,Q96PE3,O75874,P14174,Q9NRA0,P07099,Q9BRR6,Q9H488,O75521,Q99538,Q9HCL2,Q9UKG9,P31751,Q08623,Q92520,P38435,O75879,Q9UDY2,P5526... | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,5,11,12,15,14,20,23,29,32,34,38,43,45,46,48,50,57,55,66,69,70,75,82,88,90,93,94,95,101,109,113,118,121,132,137,158,160,154,162,172,174,181,199,193,200,201,203,204,215,222,227,234,237,260,274,272,266,289,280,308,302,326,325,329,319,321,348,338,342,343,362,356,370,402,401,400,383,420,424,427,408,407,410,439,443,432 | 428,1315,1367,1068,1316,1833,697,280,3112,1687,1429,2237,898,237,1430,383,1432,627,38,338,1371,490,1113,1372,3059,1028,469,2709,1168,2528,1491,2529,69,1259,945,2824,2108,2782,859,751,3268,3162,2920,1321,2531,2625,2711,132,448,753,1693,471,95,181,3126,698,75,2298,2242,990,1892,1766,302,2243,1627,1768,1896,1262,1438,725,... | 0.8204396326290617,0.10540172980990664,0.07685003800728503,0.24689976348114367,0.10540172980990664,-0.1254926486793712,0.5239685462529114,1.0831656426328216,-1.04369050099163,-0.0672262509964336,0.048211934796472365,-0.3025770869123972,0.358643578170959,1.1865840591524877,0.048211934796472365,0.873480632258922,0.048211... | 3,375 |
Abnormal urine ph | 12 | 47 | 3.538158 | 0.000403 | P11310,O75880,O43772,P23786,P53007,P00846,P48735,Q16836,P12235,Q96EY8,Q4G0N4,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,129,33,34,227,260,11,15,143,48,23,31 | 898,33,2666,3161,129,1695,260,31,2113,602,1325,1,143,2630,1842,34,1569,1181,2678,2122,11,2756,2431,475,227,1709,1575,1519,15,23,3347,272,2076,1098,48,2082,2848,819,2090,1481,420,3006,2915,1249,793,2917,3078 | 0.358643578170959,3.0081206146023467,-0.5439512892731678,-1.1719828815512887,1.7645918959276166,-0.0672262509964336,1.1349899370587961,3.030593559630485,-0.24316559991811548,0.6056479018936,0.10540172980990664,7.367385577094042,1.6412063989989234,-0.5134593662434148,-0.1254926486793712,2.985614892363513,-0.009327790283... | 3,375 |
SLC superfamily of solute carriers | 14 | 48 | 3.516901 | 0.000437 | O43772,P53007,Q96K37,Q9HC07,P41440,O95563,P12235,Q6PML9,Q9BSK2,Q6KCM7,Q70HW3,P08195,P30825,Q9H2D1 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 33,227,228,139,321,302,143,270,18,311,188,252,26,29 | 33,1491,1693,2029,302,1174,252,1900,143,1122,26,321,227,1916,2128,1509,2205,1595,311,2644,2600,2267,270,188,3213,1525,1470,546,1238,228,2735,2848,18,3214,29,1740,2975,1479,2353,139,1481,2093,400,1750,2619,1423,1548,1685 | 3.0081206146023467,0.019486354875994212,-0.0672262509964336,-0.21360297580762733,1.031106974534266,0.19054865591249434,1.1608155122181425,-0.15476681385717422,1.6412063989989234,0.21876491453847344,3.164753514554234,1.004988400356168,1.2379520800421246,-0.15476681385717422,-0.24316559991811548,0.019486354875994212,-0.2... | 3,375 |
Abnormality of circulating enzyme level | 19 | 104 | 3.499454 | 0.000466 | P11310,Q969X5,Q9HC07,Q16836,P12235,Q8NFF5,P50416,O43772,P23786,Q08J23,Q96RL7,O75879,P46020,Q9BUK6,Q9NWM8,Q15120,Q96RR1,Q15056,O14979 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,135,139,15,143,272,266,33,34,41,51,181,192,79,83,90,219,233,110 | 944,3242,110,2527,33,1377,2920,659,1763,630,181,1894,449,1896,3079,1697,2487,1770,2536,902,1383,1,143,3025,2582,1776,603,2187,34,1219,830,2676,1568,2493,2122,1221,1039,956,911,192,2371,2756,605,266,1222,1572,1916,1575,1786,2758,2637,1132,2898,1087,671,41,1853,1283,2642,1090,3352,233,90,1517,1593,15,2727,296,3157,1232,2... | 0.33082515613705404,-1.5644818109642689,1.9111150023933372,-0.45274711809482365,3.0081206146023467,0.07685003800728503,-0.7598800080904538,0.5512660173470204,-0.09631286647900751,0.5784922208777676,1.416015523904057,-0.15476681385717422,0.7938228645047847,-0.15476681385717422,-0.980035309228183,-0.0672262509964336,-0.4... | 3,375 |
SLC25 family of mitochondrial transporters | 7 | 23 | 3.437033 | 0.000588 | O43772,P53007,P12235,Q9BSK2,Q6KCM7,Q70HW3,Q9H2D1 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 33,227,143,18,311,188,29 | 33,1491,1693,1174,143,1122,227,1509,2205,311,2600,188,1525,2848,18,29,1479,1481,2093,400,1750,1423,1548 | 3.0081206146023467,0.019486354875994212,-0.0672262509964336,0.19054865591249434,1.6412063989989234,0.21876491453847344,1.2379520800421246,0.019486354875994212,-0.2728238448155597,1.031106974534266,-0.4830577925150717,1.39073841091754,0.019486354875994212,-0.6668117578076647,3.6904267756578513,3.1201613747468726,0.04821... | 3,375 |
Mitochondrial carrier domain superfamily [IPR023395] | 7 | 23 | 3.437033 | 0.000588 | O43772,P53007,P12235,Q9BSK2,Q6KCM7,Q70HW3,Q9H2D1 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 33,227,143,18,311,188,29 | 33,1491,1693,1174,143,1122,227,1509,2205,311,2600,188,1525,2848,18,29,1479,1481,2093,400,1750,1423,1548 | 3.0081206146023467,0.019486354875994212,-0.0672262509964336,0.19054865591249434,1.6412063989989234,0.21876491453847344,1.2379520800421246,0.019486354875994212,-0.2728238448155597,1.031106974534266,-0.4830577925150717,1.39073841091754,0.019486354875994212,-0.6668117578076647,3.6904267756578513,3.1201613747468726,0.04821... | 3,375 |
Mitochondrial substrate/solute carrier [IPR018108] | 7 | 23 | 3.437033 | 0.000588 | O43772,P53007,P12235,Q9BSK2,Q6KCM7,Q70HW3,Q9H2D1 | Sequence | InterPro Repeat | interpro_repeat | 33,227,143,18,311,188,29 | 33,1491,1693,1174,143,1122,227,1509,2205,311,2600,188,1525,2848,18,29,1479,1481,2093,400,1750,1423,1548 | 3.0081206146023467,0.019486354875994212,-0.0672262509964336,0.19054865591249434,1.6412063989989234,0.21876491453847344,1.2379520800421246,0.019486354875994212,-0.2728238448155597,1.031106974534266,-0.4830577925150717,1.39073841091754,0.019486354875994212,-0.6668117578076647,3.6904267756578513,3.1201613747468726,0.04821... | 3,375 |
Metabolism of lipids | 29 | 182 | 3.422867 | 0.00062 | P11310,Q9NPH0,Q8IV08,O75521,Q8N8N7,Q16739,Q99538,Q15392,Q9BR61,Q16836,Q9HCL2,Q9UKG9,O43772,P23786,O15121,P38435,Q96G23,Q9H2C2,P43304,Q9BY49,P30084,Q16850,Q9BWD1,Q96PE3,P53007,Q15800,Q9C0D9,Q9NRA0,O14734 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1,2,3,132,5,133,137,12,275,15,158,160,33,34,38,174,54,66,200,203,204,82,88,94,227,234,106,109,237 | 2526,1068,1316,795,1687,2237,237,2575,38,338,1371,490,1113,1167,33,1491,2358,2108,750,1320,2531,2177,132,2787,1766,2535,2299,2243,2923,1768,661,1962,2113,602,3269,1382,2924,3329,1771,860,3129,1,1840,2830,3331,3243,1634,2364,2116,1498,3042,1328,1842,908,2118,2489,34,2368,204,341,955,407,3116,1569,521,174,2122,408,1571,2... | -0.45274711809482365,0.24689976348114367,0.10540172980990664,0.44164086630862914,-0.0672262509964336,-0.3025770869123972,1.1865840591524877,-0.4830577925150717,2.8043654472386006,0.952569994453112,0.07685003800728503,0.7403936172598823,0.21876491453847344,0.19054865591249434,3.0081206146023467,0.019486354875994212,-0.3... | 3,375 |
Myopathy | 17 | 103 | 3.41964 | 0.000627 | P11310,P23786,Q96RR1,P53007,P00846,Q969X5,O95155,Q13126,Q15056,Q9BUK6,O14979,P12235,Q9NWM8,Q96RL7,O43676,Q8NCH0,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,34,219,227,260,135,42,43,233,79,110,143,83,51,177,185,31 | 897,3112,3242,110,177,1377,945,659,581,1763,630,2110,42,1894,494,2244,260,3079,31,1697,2487,1770,2536,902,2031,2302,1,143,3025,1634,2364,2582,1329,1776,603,34,1219,830,2676,1568,2122,1221,1039,757,1848,605,1222,731,1572,227,1575,1786,2758,2796,2637,1509,1455,2500,1087,671,1716,43,1853,1283,2642,1090,233,1517,1593,435,3... | 0.358643578170959,-1.04369050099163,-1.5644818109642689,1.9111150023933372,1.441240326714265,0.07685003800728503,0.33082515613705404,0.5512660173470204,0.6327337919013768,-0.09631286647900751,0.5784922208777676,-0.24316559991811548,2.7129169777181765,-0.15476681385717422,0.7403936172598823,-0.3025770869123972,1.1349899... | 3,375 |
Organic aciduria | 10 | 42 | 3.377645 | 0.000731 | P11310,O75880,O43772,P23786,P53007,P48735,Q16836,P12235,Q96EY8,Q4G0N4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,129,33,34,227,11,15,143,48,23 | 898,33,2666,3161,129,1695,2113,602,1325,1,143,2630,1842,34,1569,1181,2678,2122,11,2756,2431,475,227,1709,1575,1519,15,23,3347,272,2076,1098,48,2082,819,2090,1481,420,3006,2915,1249,2917 | 0.358643578170959,3.0081206146023467,-0.5439512892731678,-1.1719828815512887,1.7645918959276166,-0.0672262509964336,-0.24316559991811548,0.6056479018936,0.10540172980990664,7.367385577094042,1.6412063989989234,-0.5134593662434148,-0.1254926486793712,2.985614892363513,-0.009327790283860563,0.19054865591249434,-0.5439512... | 3,375 |
Organic acid transmembrane transport | 11 | 33 | 3.363095 | 0.000771 | O43772,P23786,P53007,P41440,O95563,Q8TDW0,P08195,P50416,P30825,Q9H2D1,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 33,34,227,321,302,312,252,266,26,29,154 | 898,33,514,1693,1436,302,1263,2894,252,1900,34,1218,26,154,955,321,266,227,1916,2205,2903,1595,312,2735,2848,29,1740,1479,2353,400,1750,2619,1423 | 0.358643578170959,3.0081206146023467,0.713579835070738,-0.0672262509964336,0.048211934796472365,1.031106974534266,0.13386805297961285,-0.7287703736920425,1.1608155122181425,-0.15476681385717422,2.985614892363513,0.16225002844017103,3.164753514554234,1.5665946676492313,0.33082515613705404,1.004988400356168,1.10910682085... | 3,375 |
Glucose metabolic process | 15 | 55 | 3.36081 | 0.000777 | Q9UNI6,P11310,Q9UBX3,P49841,P53007,Q92520,Q6PJG6,Q93009,P50416,Q9BYT8,Q00796,Q9BRR6,Q15120,P31751,Q9Y6N1 | Processes and pathways | GO Biological process | msigdb_gobp | 402,1,400,32,227,172,201,443,266,57,432,118,90,154,427 | 1367,697,1687,1372,1693,471,2244,2712,1322,2361,1699,1561,3142,1383,2114,1772,1,1120,2115,1077,1217,154,2493,1130,805,32,266,917,227,2796,997,2836,2377,432,2055,2899,673,3104,90,1135,1348,1051,201,2340,172,443,1202,2399,118,57,2007,400,1750,402,427 | 0.07685003800728503,0.5239685462529114,-0.0672262509964336,0.07685003800728503,-0.0672262509964336,0.7671410746721091,-0.3025770869123972,-0.5745330198140897,0.10540172980990664,-0.36236611826561227,-0.0672262509964336,-0.009327790283860563,-1.1076741576662066,0.07685003800728503,-0.24316559991811548,-0.096312866479007... | 3,375 |
Endoplasmic reticulum | 137 | 493 | 3.354939 | 0.000794 | Q8IV08,Q9Y394,Q15392,Q14257,Q03001,O15260,Q99497,O95456,P80303,P37268,P30519,Q96LJ7,Q8TB61,Q8NFQ8,O95881,O15121,Q86XL3,Q9NUQ7,Q96RL7,Q96KC8,Q8TCT9,Q96G23,P28161,Q92791,Q96CS3,Q32P28,Q9H2C2,O43865,Q8IXB1,Q9Y3A6,P21399,O15460,P13674,O75718,Q8N766,P07942,Q8N4V1,Q9NWM8,Q9P2W9,Q16850,Q9UMX5,O43852,Q8NHP6,Q96AA3,Q12933,Q9Y28... | Localization | GO Cellular component | msigdb_gocc | 3,535,12,16,17,19,20,517,22,521,24,25,546,545,538,38,44,575,51,569,564,54,557,56,566,65,66,69,72,598,70,74,76,78,589,582,81,83,84,82,89,85,613,618,96,99,102,103,105,106,605,109,607,608,113,645,118,647,121,124,650,655,652,627,135,136,635,636,638,151,150,686,688,157,694,676,174,175,665,178,182,183,198,197,211,213,221,230... | 2526,428,3153,1317,897,280,3160,3313,2237,3022,1256,1215,898,2575,1430,281,1760,627,38,489,1070,19,490,1113,3308,74,1433,723,290,3023,3231,2664,1167,85,69,2108,282,859,3162,2920,1887,1492,3097,1763,2176,2711,3284,753,78,1765,471,1436,2110,2786,699,1261,3361,2298,1032,1379,301,259,2787,3127,517,1766,2535,2299,2243,2671,... | -0.45274711809482365,0.8204396326290617,-1.1397880951540584,0.10540172980990664,0.358643578170959,1.0831656426328216,-1.1719828815512887,-2.104720346998251,-0.3025770869123972,-0.8851760478860837,0.13386805297961285,0.16225002844017103,0.358643578170959,-0.4830577925150717,0.048211934796472365,1.0831656426328216,-0.096... | 3,375 |
Energy derivation by oxidation of organic compounds | 21 | 131 | 3.3302 | 0.000868 | P11310,Q04446,Q13423,P00846,P48735,Q9BSK2,Q99497,P31751,P03886,P49841,O43678,P13807,P14406,O43676,Q9NZ45,P46020,P43304,P21399,O75874,O14949,Q96QE5 | Processes and pathways | GO Biological process | msigdb_gobp | 1,261,262,260,11,18,20,154,31,32,291,167,49,177,67,192,200,70,95,231,127 | 2103,3096,231,2665,177,291,385,2529,1321,1690,581,2625,2241,1693,95,3126,698,493,1172,901,1695,494,260,31,1962,3237,1322,1698,1073,1324,2748,1561,3142,1265,1326,1383,2114,1564,1772,802,1,2986,2630,167,49,2829,519,3330,1175,2953,827,70,1329,2539,1177,2037,664,2584,2674,1843,1219,154,539,1331,1568,2369,1844,2427,2678,150... | -0.24316559991811548,-1.0118216311731156,1.212296082730813,-0.5439512892731678,1.441240326714265,1.057165873125376,0.873480632258922,-0.45274711809482365,0.10540172980990664,-0.0672262509964336,0.6327337919013768,-0.5134593662434148,-0.3025770869123972,-0.0672262509964336,2.031985358818018,-1.075641485634037,0.52396854... | 3,375 |
Organelle subcompartment | 116 | 397 | 3.325342 | 0.000883 | Q12846,Q8IV08,Q9Y394,Q15392,Q03001,O15260,P37268,P30519,Q8TB61,Q8NFQ8,O15121,Q86XL3,Q8NBZ7,Q96RL7,Q96CS3,Q96KC8,Q96G23,Q8TCT9,O60499,Q8N3F8,Q9H2C2,O43865,Q9Y3A6,Q8N766,O14578,Q8N4V1,Q9P2W9,Q16850,O43852,Q8NHP6,Q9H4A6,Q96AA3,Q12933,Q9Y282,P43307,Q9NZ08,Q4ZIN3,Q9C0D9,Q9H9E3,P50402,P51571,P53992,P07099,Q8NF37,Q9BRR6,Q8TC1... | Localization | GO Cellular component | msigdb_gocc | 527,3,535,12,17,19,521,24,546,545,38,44,45,51,566,569,54,564,59,61,66,69,598,589,579,81,84,82,85,613,622,618,96,99,102,103,105,106,107,605,607,608,113,645,118,647,650,655,126,135,139,136,636,638,151,148,150,159,688,694,676,662,174,665,178,179,183,198,197,209,211,215,221,230,234,232,256,259,273,279,281,280,298,309,312,3... | 2526,428,1317,897,795,2918,280,3160,2237,3022,579,1256,898,2575,1885,1430,281,1760,38,148,3338,19,490,1113,723,3023,3231,1374,209,1376,85,69,2108,59,859,3162,2920,1887,2578,3097,1763,2176,2711,1765,471,1436,2110,1261,3361,2298,1032,1379,301,259,1960,2787,990,1766,2535,2299,2243,1768,725,661,1962,318,1381,1323,2713,1698... | -0.45274711809482365,0.8204396326290617,0.10540172980990664,0.358643578170959,0.44164086630862914,-0.7598800080904538,1.0831656426328216,-1.1719828815512887,-0.3025770869123972,-0.8851760478860837,0.6327337919013768,0.13386805297961285,0.358643578170959,-0.4830577925150717,-0.15476681385717422,0.048211934796472365,1.08... | 3,375 |
EF-hand domain [IPR002048] | 16 | 43 | 3.304551 | 0.000951 | Q02818,P07384,Q9BPX6,P43304,Q15293,Q14257,Q03001,Q9NWM8,Q6KCM7,Q9BRK5,P42566,P80303,O43852,Q96AY3,Q9UPN3,P41208 | Sequence | InterPro Domain | interpro_domain | 324,68,465,200,335,16,17,83,311,213,265,22,85,124,487,216 | 1626,85,1763,1693,2029,68,1495,950,2183,2987,3201,1841,1330,1910,216,265,200,2635,22,324,17,2801,16,2965,335,1137,311,2600,924,1007,502,645,124,817,465,213,2607,1949,83,2778,891,1750,487 | -0.038231613171792155,2.1039880520769403,-0.09631286647900751,-0.0672262509964336,-0.21360297580762733,2.294161378716793,0.019486354875994212,0.33082515613705404,-0.2728238448155597,-0.82235748271142,-1.334155331699041,-0.1254926486793712,0.10540172980990664,-0.15476681385717422,1.2635525405656844,1.1091068208502726,1.... | 3,375 |
EF-Hand 1, calcium-binding site [IPR018247] | 14 | 37 | 3.286 | 0.001016 | Q02818,P07384,Q9BPX6,P43304,Q15293,Q14257,Q03001,Q9NWM8,Q9BRK5,P42566,P80303,O43852,Q96AY3,P41208 | Sequence | InterPro Binding site | interpro_binding_site | 324,68,465,200,335,16,17,83,213,265,22,85,124,216 | 1626,85,1763,1693,2029,68,1495,950,2183,2987,3201,1841,1330,1910,216,265,200,22,324,17,2801,16,2965,335,2600,924,1007,124,817,465,213,2607,1949,83,2778,891,487 | -0.038231613171792155,2.1039880520769403,-0.09631286647900751,-0.0672262509964336,-0.21360297580762733,2.294161378716793,0.019486354875994212,0.33082515613705404,-0.2728238448155597,-0.82235748271142,-1.334155331699041,-0.1254926486793712,0.10540172980990664,-0.15476681385717422,1.2635525405656844,1.1091068208502726,1.... | 3,375 |
transporter | 11 | 57 | 3.269621 | 0.001077 | Q99595,O43772,Q567V2,O60830,P53007,P41440,Q6PML9,Q9C0E2,Q9HD45,Q9H2D1,O15397 | Functions | Panther Protein class | panther_protein_class | 64,33,35,4,227,321,270,186,288,29,339 | 626,1026,2022,2944,1370,339,1886,1167,33,1115,3173,4,826,1380,2041,1570,321,2373,2992,1223,1504,1224,227,1916,1917,2050,2257,704,1925,2207,35,2644,270,1140,1602,1350,1143,709,1009,884,1354,1406,1736,64,571,2278,186,29,2975,1307,288,2703,982,690,1485,382,1423 | 0.5784922208777676,0.27495414250230754,-0.21360297580762733,-0.7910758719515134,0.07685003800728503,0.952569994453112,-0.15476681385717422,0.19054865591249434,3.0081206146023467,0.21876491453847344,-1.2042581055902233,5.415645674566234,0.41405059073486755,0.07685003800728503,-0.21360297580762733,-0.009327790283860563,1... | 3,375 |
Nuclear outer membrane endoplasmic reticulum membrane network | 95 | 314 | 3.222225 | 0.001272 | Q8IV08,Q9Y394,Q15392,Q03001,O15260,P37268,P30519,Q8TB61,Q8NFQ8,O15121,Q86XL3,Q96RL7,Q96CS3,Q96KC8,Q96G23,Q8TCT9,Q9H2C2,O43865,Q9Y3A6,Q8N766,Q8N4V1,Q9P2W9,Q16850,O43852,Q8NHP6,Q96AA3,Q12933,Q9Y282,P43307,Q9NZ08,Q4ZIN3,Q9C0D9,P50402,P51571,P53992,P07099,Q8NF37,Q9BRR6,Q8TC12,Q96HE7,Q9NXE4,Q969X5,Q96GC9,P49755,Q7Z2K6,Q9HD2... | Localization | GO Cellular component | msigdb_gocc | 3,535,12,17,19,521,24,546,545,38,44,51,566,569,54,564,66,69,598,589,81,84,82,85,613,618,96,99,102,103,105,106,605,607,608,113,645,118,647,650,655,135,136,636,638,151,150,688,694,676,174,665,178,183,198,197,211,221,230,234,232,256,259,273,281,280,298,309,312,301,318,336,348,356,355,382,377,376,398,426,407,409,410,413,44... | 2526,428,1317,897,280,3160,2237,3022,1256,898,2575,1430,281,1370,1760,38,19,490,1113,723,3023,3231,85,69,2108,859,3162,2920,3097,1763,2176,2711,1765,471,1436,2110,1261,3361,2298,1032,1379,301,259,2787,1766,2535,2299,2243,1768,725,661,318,1381,1323,1698,2361,113,1562,1440,993,452,1036,994,1037,1701,861,2117,908,1776,258... | -0.45274711809482365,0.8204396326290617,0.10540172980990664,0.358643578170959,1.0831656426328216,-1.1719828815512887,-0.3025770869123972,-0.8851760478860837,0.13386805297961285,0.358643578170959,-0.4830577925150717,0.048211934796472365,1.0831656426328216,0.07685003800728503,-0.09631286647900751,2.8043654472386006,3.668... | 3,375 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 12 | 32 | 3.211908 | 0.001319 | O00469,Q32P28,Q9BU89,O15121,Q15800,O15460,P13674,Q16850,P30519,Q6UW02,Q9NVH6,Q8N543 | Functions | GO Molecular function | msigdb_gomf | 280,65,358,38,234,74,76,82,24,58,91,123 | 280,2237,38,74,2824,859,1768,1264,993,76,994,24,1712,1455,1797,356,234,82,65,2907,1723,58,878,3239,813,123,774,358,3073,91,2778,2892 | 1.0831656426328216,-0.3025770869123972,2.8043654472386006,2.223153155757611,-0.6668117578076647,0.38638510613707605,-0.09631286647900751,0.13386805297961285,0.30292897251860446,2.223153155757611,0.30292897251860446,3.2756861538715345,-0.0672262509964336,0.048211934796472365,-0.09631286647900751,0.9262690243148245,1.212... | 3,375 |
Organic acid transport | 15 | 50 | 3.209159 | 0.001331 | O43772,P23786,P53007,P14174,P09455,P41440,O95563,Q6P4A7,Q8TDW0,P08195,P50416,P30825,Q9UKG9,Q9H2D1,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 33,34,227,101,319,321,302,269,312,252,266,26,160,29,154 | 898,2104,3242,628,33,1491,514,1693,1436,302,2243,2485,2825,1263,1963,2894,252,319,1900,101,34,1218,26,154,955,321,266,227,1916,2128,2205,673,2903,1590,1595,2267,269,3213,312,2735,2848,29,1740,1479,2353,400,1750,160,2619,1423 | 0.358643578170959,-0.24316559991811548,-1.5644818109642689,0.5784922208777676,3.0081206146023467,0.019486354875994212,0.713579835070738,-0.0672262509964336,0.048211934796472365,1.031106974534266,-0.3025770869123972,-0.42252790140681873,-0.6668117578076647,0.13386805297961285,-0.18413660636999382,-0.7287703736920425,1.1... | 3,375 |
Fatty acid metabolism | 12 | 58 | 3.206821 | 0.001342 | P11310,O43772,P23786,O75521,Q8N8N7,P53007,Q9BY49,Q9BR61,Q16836,O14734,P30084,Q9UKG9 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1,33,34,132,5,227,203,275,15,237,204,160 | 1316,1687,2237,237,1371,33,1491,2108,132,2243,1768,2113,602,1771,860,1,3331,1842,2118,34,204,955,2122,408,1571,1041,2756,266,2864,410,1975,227,1976,2758,1716,2505,737,2596,2766,15,3347,2599,500,2931,3239,5,1528,275,203,572,2354,1683,1544,822,160,1546,550,2823 | 0.10540172980990664,-0.0672262509964336,-0.3025770869123972,1.1865840591524877,0.07685003800728503,3.0081206146023467,0.019486354875994212,-0.24316559991811548,1.7400097763933111,-0.3025770869123972,-0.09631286647900751,-0.24316559991811548,0.6056479018936,-0.09631286647900751,0.38638510613707605,7.367385577094042,-2.3... | 3,375 |
Dicarboxylic aciduria | 7 | 27 | 3.200611 | 0.001371 | P11310,O75880,O43772,P23786,P48735,Q16836,Q96EY8 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,129,33,34,11,15,48 | 898,33,129,1,2630,1842,34,1569,2678,2122,11,2756,2431,227,1709,1575,1519,15,3347,2076,1098,48,819,2090,3006,2915,2917 | 0.358643578170959,3.0081206146023467,1.7645918959276166,7.367385577094042,-0.5134593662434148,-0.1254926486793712,2.985614892363513,-0.009327790283860563,-0.5439512892731678,-0.24316559991811548,4.470238014994655,-0.6052040240979027,-0.39240070950050854,1.2379520800421246,-0.0672262509964336,-0.009327790283860563,0.019... | 3,375 |
Positive regulation of cell population proliferation | 25 | 135 | 3.189017 | 0.001428 | P00813,P49366,Q9UBL3,Q99538,P43490,Q9BSK2,Q9HCL2,P30825,P31751,Q12834,Q16512,Q9UIV1,P07384,P04439,O95630,O94788,O95140,O95684,P30536,P14174,P43307,Q9NQC3,Q9NRA0,Q96GN5,Q8WWQ0 | Processes and pathways | GO Biological process | msigdb_gobp | 0,130,278,137,14,18,158,26,154,294,307,190,68,318,317,75,331,92,341,101,102,230,109,375,126 | 697,3160,1553,2824,1888,1763,1959,75,1261,331,2360,317,92,2670,2857,0,3236,2825,318,948,1174,1263,1698,3099,68,582,1440,1628,993,2302,633,101,2829,2788,1269,1634,1841,2186,1387,367,1566,2038,2189,665,2309,1909,341,26,154,1178,1179,2426,3211,1334,102,14,2793,2585,2251,2587,3046,130,3282,2495,1577,2051,1789,2130,3013,179... | 0.5239685462529114,-1.1719828815512887,-0.009327790283860563,-0.6668117578076647,-0.15476681385717422,-0.09631286647900751,-0.18413660636999382,2.223153155757611,0.13386805297961285,0.978809595175081,-0.36236611826561227,1.004988400356168,2.0560289253619395,-0.5439512892731678,-0.6977474581428348,8.05927987366474,-1.53... | 3,375 |
Monosaccharide metabolic process | 17 | 72 | 3.180409 | 0.001471 | Q9UNI6,P11310,Q9UBX3,P49841,P53007,Q92520,Q6PJG6,Q8NBZ7,Q93009,P50416,Q9BYT8,Q00796,Q9BRR6,Q9H488,Q15120,P31751,Q9Y6N1 | Processes and pathways | GO Biological process | msigdb_gobp | 402,1,400,32,227,172,201,45,443,266,57,432,118,121,90,154,427 | 1367,697,3112,1687,1372,1693,471,2244,1769,1697,2712,1322,2361,1699,1561,3142,1074,1383,2114,1900,1772,1,1120,2115,3009,2830,3243,1077,1217,154,2194,2493,1848,1130,805,32,266,2048,1642,917,227,2796,997,2836,2377,1647,432,2055,2899,673,3104,90,1135,1348,1051,201,2340,45,172,443,1202,2399,118,1299,57,121,2007,400,1750,10... | 0.07685003800728503,0.5239685462529114,-1.04369050099163,-0.0672262509964336,0.07685003800728503,-0.0672262509964336,0.7671410746721091,-0.3025770869123972,-0.09631286647900751,-0.0672262509964336,-0.5745330198140897,0.10540172980990664,-0.36236611826561227,-0.0672262509964336,-0.009327790283860563,-1.1076741576662066,... | 3,375 |
Fatty acid beta oxidation | 11 | 36 | 3.157791 | 0.00159 | P11310,P42126,P23786,O75521,Q16836,O14734,P30084,P50416,Q9BWD1,Q9UKG9,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 1,408,34,132,15,237,204,266,88,160,154 | 1687,898,237,1371,1491,132,1771,1,2630,2118,34,2368,1446,1218,204,154,407,2678,2122,408,1571,2756,266,606,1975,2758,3068,737,1519,15,2931,2076,2974,88,3169,160 | -0.0672262509964336,0.358643578170959,1.1865840591524877,0.07685003800728503,0.019486354875994212,1.7400097763933111,-0.09631286647900751,7.367385577094042,-0.5134593662434148,-0.24316559991811548,2.985614892363513,-0.36236611826561227,0.048211934796472365,0.16225002844017103,1.3145887721057432,1.5665946676492313,0.846... | 3,375 |
Sensory neuropathy | 12 | 37 | 3.14019 | 0.001688 | Q96RR1,Q8IV08,P07384,Q9H0B6,P00846,O95831,O95140,Q03001,Q96RL7,P00403,Q9NSE4,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 219,3,68,360,260,449,331,17,51,494,222,31 | 490,1113,2666,1377,945,2298,331,449,494,260,31,68,902,1217,603,1566,1331,2122,1335,2315,1575,1786,2758,2376,17,1654,3118,2903,737,3,1869,2147,51,219,360,222,2823 | 0.7403936172598823,0.21876491453847344,-0.5439512892731678,0.07685003800728503,0.33082515613705404,-0.33242471265450957,0.978809595175081,0.7938228645047847,0.7403936172598823,1.1349899370587961,3.030593559630485,2.294161378716793,0.358643578170959,0.16225002844017103,0.6056479018936,-0.009327790283860563,0.10540172980... | 3,375 |
Peptidase activity | 41 | 113 | 3.137253 | 0.001705 | Q9NQH7,Q86UV5,P55786,Q4J6C6,Q16740,Q99538,P50579,O43847,Q7Z2K6,Q99497,P14735,Q92890,Q9Y4E8,Q96BN8,Q5JRX3,Q6P179,P49721,Q9Y4W6,Q9P0U3,Q9NUQ7,Q8IYS1,Q13867,Q93009,Q8TCT9,Q9BYT8,P28070,Q96K76,P07384,P51784,Q99436,O95630,Q9BXS4,P60900,Q96RU2,Q0VDG4,P28072,O75844,Q9NZ08,P28074,Q9H8M7,Q86TI2 | Functions | GO Molecular function | msigdb_gomf | 263,396,7,393,9,137,389,386,638,20,519,150,425,417,296,676,40,578,576,575,439,46,443,564,57,556,63,68,322,464,317,352,344,620,97,472,471,103,238,653,641 | 2236,1835,2105,749,3231,386,947,471,3163,1031,1032,317,3236,68,860,3129,1565,1327,519,3201,803,2539,1905,556,472,238,3143,1778,910,1181,667,729,1706,1912,2429,2046,2680,40,389,2432,322,2256,1224,1849,7,344,1278,2762,97,999,2262,2899,46,1516,875,9,393,1460,296,770,3326,1865,676,2214,3168,1293,638,641,396,439,1399,564,23... | -0.3025770869123972,-0.1254926486793712,-0.24316559991811548,0.4691567512932392,-1.4653079613874214,0.873480632258922,0.33082515613705404,0.7671410746721091,-1.1719828815512887,0.27495414250230754,0.27495414250230754,1.004988400356168,-1.5313475075418816,2.294161378716793,0.38638510613707605,-1.075641485634037,-0.00932... | 3,375 |
Lipid modification | 13 | 50 | 3.133195 | 0.001729 | P11310,P42126,P23786,O75521,P35610,Q9NRA0,Q16836,O14734,P30084,P50416,Q9BWD1,Q9UKG9,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 1,408,34,132,407,109,15,237,204,266,88,160,154 | 428,1687,898,237,1371,1491,132,1962,1771,1,1075,2630,994,2118,34,2368,1446,1218,204,154,407,2678,2122,408,1571,2756,266,606,1975,2758,2898,999,3068,673,737,1519,1348,15,768,1807,2931,2076,1151,2974,88,109,2283,3169,822,160 | 0.8204396326290617,-0.0672262509964336,0.358643578170959,1.1865840591524877,0.07685003800728503,0.019486354875994212,1.7400097763933111,-0.18413660636999382,-0.09631286647900751,7.367385577094042,0.24689976348114367,-0.5134593662434148,0.30292897251860446,-0.24316559991811548,2.985614892363513,-0.36236611826561227,0.04... | 3,375 |
dehydrogenase | 11 | 67 | 3.129801 | 0.001749 | P11310,P43304,P48735,O94788,Q96EY8,Q96CU9,Q96LJ7,P30837,Q3SXM5,O75874,P03886 | Functions | Panther Protein class | panther_protein_class | 1,200,11,75,48,86,25,55,218,95,31 | 1028,2529,3268,1690,2241,95,75,1896,1262,31,2712,726,1118,3142,1772,1,1120,1075,1496,2953,2184,1329,1635,828,1446,2584,953,55,1219,1273,1502,2719,200,1040,11,2047,3307,2756,1784,410,475,1642,3244,1576,432,2799,1649,2960,262,218,1599,3222,2931,647,1199,2076,86,48,25,1016,819,2090,1683,2096,1249,1106,535 | 0.27495414250230754,-0.45274711809482365,-1.7312845351077755,-0.0672262509964336,-0.3025770869123972,2.031985358818018,2.223153155757611,-0.15476681385717422,0.13386805297961285,3.030593559630485,-0.5745330198140897,0.49659904864423754,0.21876491453847344,-1.1076741576662066,-0.09631286647900751,7.367385577094042,0.218... | 3,375 |
Fatty acid metabolism | 10 | 28 | 3.103203 | 0.001914 | P11310,P42126,P23786,O75521,P35610,Q16836,P30084,P50416,Q9BWD1,P30837 | Processes and pathways | KEGG Pathways | msigdb_kegg | 1,408,34,132,407,15,204,266,88,55 | 1371,2108,132,2243,726,1771,1,1075,34,2368,204,55,955,407,2122,408,1571,1040,2047,3307,2756,266,410,2758,737,15,2076,88 | 0.07685003800728503,-0.24316559991811548,1.7400097763933111,-0.3025770869123972,0.49659904864423754,-0.09631286647900751,7.367385577094042,0.24689976348114367,2.985614892363513,-0.36236611826561227,1.3145887721057432,2.4584637978137454,0.33082515613705404,0.8469920138668321,-0.24316559991811548,0.8469920138668321,-0.00... | 3,375 |
Protease | 34 | 83 | 3.071156 | 0.002132 | Q9NQH7,Q86UV5,P55786,Q4J6C6,Q16740,Q99538,P50579,O43847,Q7Z2K6,Q99497,P14735,Q9Y4E8,Q96BN8,Q5JRX3,Q6P179,Q9Y4W6,Q9P0U3,Q9NUQ7,Q13867,Q93009,Q8TCT9,Q9BYT8,Q96K76,P07384,P51784,Q99436,O95630,Q96RU2,P28072,O75844,Q9NZ08,P28074,Q9H8M7,Q86TI2 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 263,396,7,393,9,137,389,386,638,20,519,425,417,296,676,578,576,575,46,443,564,57,63,68,322,464,317,620,472,471,103,238,653,641 | 2236,1835,2105,3231,386,947,471,3163,1032,317,68,860,3129,1565,519,3201,472,238,3143,1778,667,729,1706,1912,2429,2046,389,322,2256,1224,1849,7,1278,2762,46,1516,875,9,393,296,770,3326,1865,676,3168,638,641,396,1399,564,1473,2000,778,443,417,2151,1533,63,2225,620,2464,464,20,137,1356,57,3367,1676,1154,653,3273,263,1105,... | -0.3025770869123972,-0.1254926486793712,-0.24316559991811548,-1.4653079613874214,0.873480632258922,0.33082515613705404,0.7671410746721091,-1.1719828815512887,0.27495414250230754,1.004988400356168,2.294161378716793,0.38638510613707605,-1.075641485634037,-0.009327790283860563,0.713579835070738,-1.334155331699041,0.767141... | 3,375 |
Fatty acid betaoxidation | 8 | 19 | 3.068775 | 0.002149 | P11310,P23786,O43772,P42126,P43304,Q16836,P30084,P50416 | Processes and pathways | WikiPathways | msigdb_wp | 1,34,33,408,200,15,204,266 | 33,2108,2243,1326,1,34,2368,204,955,407,2122,408,200,2756,266,2758,2796,15,2076 | 3.0081206146023467,-0.24316559991811548,-0.3025770869123972,0.10540172980990664,7.367385577094042,2.985614892363513,-0.36236611826561227,1.3145887721057432,0.33082515613705404,0.8469920138668321,-0.24316559991811548,0.8469920138668321,1.340025485497747,-0.6052040240979027,1.1091068208502726,-0.6052040240979027,-0.63596... | 3,375 |
Lipid oxidation | 12 | 42 | 3.054374 | 0.002255 | P11310,P23786,P42126,O75521,P35610,Q16836,O14734,P30084,P50416,Q9BWD1,Q9UKG9,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 1,34,408,132,407,15,237,204,266,88,160,154 | 428,1687,898,237,1371,1491,132,1771,1,1075,2630,994,2118,34,2368,1446,1218,204,154,407,2678,2122,408,1571,2756,266,606,1975,2758,3068,673,737,1519,1348,15,2931,2076,2974,88,3169,822,160 | 0.8204396326290617,-0.0672262509964336,0.358643578170959,1.1865840591524877,0.07685003800728503,0.019486354875994212,1.7400097763933111,-0.09631286647900751,7.367385577094042,0.24689976348114367,-0.5134593662434148,0.30292897251860446,-0.24316559991811548,2.985614892363513,-0.36236611826561227,0.048211934796472365,0.16... | 3,375 |
Oxidoreductase | 31 | 117 | 3.0499 | 0.002289 | P11310,O75880,Q13423,Q8N8N7,Q15392,O43819,O15260,P03886,O00469,O95881,O43678,Q9H7Z7,P14406,Q00796,P30837,P43304,O94788,Q9BY49,O95831,O75306,P00390,P23921,Q16850,Q96CU9,P51649,Q15800,Q14534,O43169,Q8TC12,P00403,O95168 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 1,129,262,5,12,385,19,31,280,538,291,572,49,432,55,200,75,203,449,581,450,583,82,86,475,234,356,116,647,494,493 | 280,2103,3096,1371,19,116,1028,2665,291,385,2529,1690,581,129,2784,75,493,449,538,1896,1262,1438,450,494,31,3237,2712,726,1118,992,1326,1564,1,1120,1075,2630,1385,49,3009,3330,2830,1175,827,1329,1635,828,583,1446,2584,1908,2751,1909,55,1219,1220,1273,1781,1181,2678,1502,2719,200,2047,3307,2756,1784,475,1573,1642,3244,1... | 1.0831656426328216,-0.24316559991811548,-1.0118216311731156,0.07685003800728503,3.6688559426474816,1.862456329832627,0.27495414250230754,-0.5439512892731678,1.057165873125376,0.873480632258922,-0.45274711809482365,-0.0672262509964336,0.6327337919013768,1.7645918959276166,-0.6359637761900813,2.223153155757611,0.74039361... | 3,375 |
Regulation of glucose metabolic process | 9 | 25 | 3.042034 | 0.00235 | Q9UNI6,P11310,P49841,Q92520,Q93009,Q9BYT8,Q15120,P31751,Q9Y6N1 | Processes and pathways | GO Biological process | msigdb_gobp | 402,1,32,172,443,57,90,154,427 | 1367,1687,1372,1693,471,1322,1,154,1130,805,32,997,2836,2377,2899,3104,90,1135,172,443,1202,57,2007,402,427 | 0.07685003800728503,-0.0672262509964336,0.07685003800728503,-0.0672262509964336,0.7671410746721091,0.10540172980990664,7.367385577094042,1.5665946676492313,0.21876491453847344,0.44164086630862914,3.030593559630485,0.30292897251860446,-0.6668117578076647,-0.36236611826561227,-0.7287703736920425,-1.0118216311731156,2.080... | 3,375 |
Small molecule biosynthetic process | 32 | 146 | 3.037413 | 0.002386 | P00813,P78330,P11310,Q9UBX3,Q15392,P08243,Q99497,P37268,O00469,O15121,Q92520,Q13126,Q9H7Z7,Q99707,Q93009,Q9BYT8,Q00796,A1L0T0,Q9H2C2,P09455,P55263,O94788,Q9BY49,Q16850,Q8NI60,P53007,P14174,Q15800,Q9NRA0,O14734,O15269,Q86YH6 | Processes and pathways | GO Biological process | msigdb_gobp | 0,526,1,400,12,518,20,521,280,38,172,43,572,570,443,57,432,428,66,319,193,75,203,82,93,227,101,234,109,237,490,370 | 428,1367,1316,280,1687,1429,2237,237,1430,38,490,1113,1372,3059,1028,859,751,3268,1321,2711,1693,75,2298,2242,1768,1262,1438,725,2857,1839,2485,2244,0,661,1962,2825,1897,1699,1560,518,992,319,860,1,1120,2115,1965,101,1840,3009,2830,3331,994,1902,907,908,2118,2489,1176,1777,557,1218,2311,3255,2955,1331,2835,1569,2493,52... | 0.8204396326290617,0.07685003800728503,0.10540172980990664,1.0831656426328216,-0.0672262509964336,0.048211934796472365,-0.3025770869123972,1.1865840591524877,0.048211934796472365,2.8043654472386006,0.7403936172598823,0.21876491453847344,0.07685003800728503,-0.948331973940958,0.27495414250230754,0.38638510613707605,0.46... | 3,375 |
Regulation of defense response | 31 | 95 | 2.99518 | 0.002743 | P00813,Q13546,P12956,O43657,Q99497,Q96PK6,Q9UKG1,Q92890,Q9BXW9,Q9NUD5,Q9Y4E8,Q9UHD2,Q96BN8,Q9Y3Z3,Q6UWE0,Q16512,P28070,Q9BUI4,Q9UIV1,Q7Z434,P04439,Q8ND56,Q9UII4,P60900,O75844,Q9NZ08,O15360,Q96EP0,Q7Z739,Q8IXJ6,Q86UT6 | Processes and pathways | GO Biological process | msigdb_gobp | 0,528,8,384,20,681,152,150,419,685,425,689,417,692,542,307,556,189,190,196,318,462,224,344,471,103,115,374,501,372,241 | 115,2984,384,1374,2482,1116,3039,471,1891,1261,900,0,1962,2825,318,2713,2486,2030,2180,1628,1631,3327,8,1267,1701,1841,907,952,2424,2038,2189,556,2492,3174,1334,956,1127,831,1275,344,2959,1648,2056,671,1229,2996,873,2764,528,1854,2446,1927,1518,2967,2266,307,1348,2211,3167,542,196,501,2396,241,372,3188,1053,462,2694,25... | 1.862456329832627,-0.82235748271142,0.873480632258922,0.07685003800728503,-0.42252790140681873,0.21876491453847344,-0.9167120699523604,0.7671410746721091,-0.15476681385717422,0.13386805297961285,0.358643578170959,8.05927987366474,-0.18413660636999382,-0.6668117578076647,1.004988400356168,-0.5745330198140897,-0.42252790... | 3,375 |
Generation of precursor metabolites and energy | 27 | 193 | 2.972346 | 0.002955 | P11310,Q04446,Q13423,P00846,P48735,P12235,Q9BSK2,Q99497,Q9UKG9,P31751,P03886,P49841,O15121,O43678,P13807,P14406,O43676,Q9NZ45,P46020,P43304,P21399,O15460,O75874,O14949,Q9NRA0,Q9BRR6,Q96QE5 | Processes and pathways | GO Biological process | msigdb_gobp | 1,261,262,260,11,143,18,20,160,154,31,32,38,291,167,49,177,67,192,200,70,74,95,231,109,118,127 | 697,2103,3096,231,38,1372,74,1028,2665,177,291,385,2529,1321,1690,581,2531,2625,2241,1693,95,3126,698,493,1172,901,2418,1695,1896,450,494,2244,260,31,1962,1697,3237,2712,1322,2713,726,1698,1073,2361,1324,1699,2748,1561,3142,1265,992,1326,1074,1383,2114,1564,1772,802,1,1120,1075,143,2986,2630,167,49,1773,2829,519,3330,2... | 0.5239685462529114,-0.24316559991811548,-1.0118216311731156,1.212296082730813,2.8043654472386006,0.07685003800728503,2.223153155757611,0.27495414250230754,-0.5439512892731678,1.441240326714265,1.057165873125376,0.873480632258922,-0.45274711809482365,0.10540172980990664,-0.0672262509964336,0.6327337919013768,-0.45274711... | 3,375 |
Regulation of small molecule metabolic process | 14 | 54 | 2.969922 | 0.002979 | Q9UNI6,P11310,P49841,Q9H2C2,O75844,Q92520,Q9NRA0,Q93009,Q99497,P50416,Q9BYT8,Q15120,P31751,Q9Y6N1 | Processes and pathways | GO Biological process | msigdb_gobp | 402,1,32,66,471,172,109,443,20,266,57,90,154,427 | 1367,1687,1372,751,2531,2711,1693,471,2298,494,2825,1322,2713,2361,2301,1,994,2715,907,664,154,2369,3211,2756,1130,805,32,266,2127,1786,1787,997,2836,2377,2899,673,3104,90,1135,2267,2343,776,172,1999,443,1202,20,57,66,2007,109,2356,402,427 | 0.07685003800728503,-0.0672262509964336,0.07685003800728503,0.4691567512932392,-0.45274711809482365,-0.5745330198140897,-0.0672262509964336,0.7671410746721091,-0.33242471265450957,0.7403936172598823,-0.6668117578076647,0.10540172980990664,-0.5745330198140897,-0.36236611826561227,-0.33242471265450957,7.367385577094042,0... | 3,375 |
EF-hand domain pair [IPR011992] | 16 | 49 | 2.945688 | 0.003222 | Q02818,P07384,Q9BPX6,P43304,Q15293,Q14257,Q03001,Q9NWM8,Q6KCM7,Q9BRK5,P42566,P80303,O43852,Q96AY3,Q9UPN3,P41208 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 324,68,465,200,335,16,17,83,311,213,265,22,85,124,487,216 | 1626,85,1763,1693,2029,68,1495,950,2183,2987,3201,1841,1330,1910,216,265,200,540,2635,2722,22,324,17,2801,16,2965,335,1137,311,2600,2603,924,1007,502,1813,645,124,817,3228,465,213,2607,1949,653,83,2778,891,1750,487 | -0.038231613171792155,2.1039880520769403,-0.09631286647900751,-0.0672262509964336,-0.21360297580762733,2.294161378716793,0.019486354875994212,0.33082515613705404,-0.2728238448155597,-0.82235748271142,-1.334155331699041,-0.1254926486793712,0.10540172980990664,-0.15476681385717422,1.2635525405656844,1.1091068208502726,1.... | 3,375 |
Coma | 9 | 38 | 2.912232 | 0.003589 | P11310,O43772,P23786,Q13423,Q16836,Q96EY8,P50416,Q9HCC0,P31751 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,33,34,262,15,48,266,420,154 | 697,33,1262,2713,2113,602,1325,2363,1,2630,1635,1842,34,2368,1446,154,1179,407,3256,1569,2678,3211,2122,1130,266,1575,2758,262,876,1519,15,2878,48,2082,420,689,1750,1423 | 0.5239685462529114,3.0081206146023467,0.13386805297961285,-0.5745330198140897,-0.24316559991811548,0.6056479018936,0.10540172980990664,-0.36236611826561227,7.367385577094042,-0.5134593662434148,-0.038231613171792155,-0.1254926486793712,2.985614892363513,-0.36236611826561227,0.048211934796472365,1.5665946676492313,0.190... | 3,375 |
Ion transmembrane transport | 45 | 167 | 2.910732 | 0.003606 | Q9UBX3,Q13546,Q13423,P00846,Q9HC07,Q96GC9,Q9UHG3,P12235,O60831,Q6PML9,Q6P4A7,Q99497,Q9HD20,Q8N668,P30825,Q9H2D1,Q8WWC4,Q8TB61,P31930,O43772,P46939,P61421,Q9Y4W6,Q6YHU6,Q9UI12,P42858,Q8TDW0,Q6KCM7,P28161,O95563,Q70HW3,P07384,O43865,Q9BPX6,P41440,Q8N4V1,P54652,P53007,P46934,O75844,Q6P4Q7,Q8IYU8,Q9NRA0,P00403,P08195 | Processes and pathways | GO Biological process | msigdb_gobp | 400,528,262,260,139,136,13,143,514,270,269,20,151,285,26,29,286,546,539,33,540,293,578,413,447,175,312,311,557,302,188,68,69,465,321,81,476,227,473,471,357,502,109,494,252 | 625,722,2103,3096,2104,628,1626,33,1491,69,1556,514,946,2239,1690,947,1693,471,1436,3126,698,2029,302,2670,494,260,2179,2628,2713,1174,1263,1073,2580,68,1964,2894,252,1265,662,1495,1564,1120,143,1122,2986,1037,1634,2364,1841,1444,827,2716,1123,2247,700,1177,2037,2834,2190,557,2674,1330,26,539,3256,2718,1844,2542,1448,3... | 0.5784922208777676,0.49659904864423754,-0.24316559991811548,-1.0118216311731156,-0.24316559991811548,0.5784922208777676,-0.038231613171792155,3.0081206146023467,0.019486354875994212,2.2705322165054698,-0.009327790283860563,0.713579835070738,0.33082515613705404,-0.3025770869123972,-0.0672262509964336,0.33082515613705404... | 3,375 |
Protein localization | 22 | 76 | 2.870685 | 0.004096 | O75521,O60830,P12235,P14735,Q9NS69,Q9UKG9,Q5JRX3,Q15388,P49069,P51648,Q7L5D6,Q3ZCQ8,Q99595,Q9BY49,Q13505,P46379,O15228,O75874,P50402,P50542,Q5T8D3,O14734 | Processes and pathways | Reactome Pathways | msigdb_reactome | 132,4,143,519,27,160,296,37,409,410,184,437,64,203,334,453,338,95,605,606,500,237 | 1068,237,1216,338,1371,1886,1167,1375,1491,2666,4,2625,2297,947,132,1693,95,1891,1696,2713,1073,1265,1771,993,2181,143,1122,519,700,2118,2037,1218,1569,3010,1081,453,409,605,606,410,1975,2129,999,3068,1282,334,737,37,437,296,500,184,644,1527,1814,1667,778,1098,64,1941,1016,203,1308,2703,27,1209,2011,822,1750,160,2235,1... | 0.24689976348114367,1.1865840591524877,0.16225002844017103,0.952569994453112,0.07685003800728503,-0.15476681385717422,0.19054865591249434,0.07685003800728503,0.019486354875994212,-0.5439512892731678,5.415645674566234,-0.5134593662434148,-0.33242471265450957,0.33082515613705404,1.7400097763933111,-0.0672262509964336,2.0... | 3,375 |
Endoplasmic reticulum lumen | 22 | 58 | 2.870031 | 0.004104 | Q14257,Q9P2K2,O95881,Q6P179,P27797,Q32P28,Q02818,Q8IXB1,Q15293,O15460,P13674,Q07065,O75718,P07942,Q9NWM8,O43852,Q13217,Q9NZ08,Q9H497,P19022,Q96HE7,Q96AY3 | Localization | GO Cellular component | msigdb_gocc | 16,686,538,676,665,65,324,72,335,74,76,455,78,582,83,85,477,103,246,495,650,124 | 3313,1215,74,1167,85,859,78,2110,538,2713,1264,582,1035,2302,2033,76,2987,1036,495,2749,2189,665,1272,2309,1780,910,701,2255,3315,324,455,477,16,1134,920,335,65,1004,676,1729,2067,72,882,1731,841,2077,124,650,972,1102,1299,246,83,2407,103,686,2469,1830 | -2.104720346998251,0.16225002844017103,2.223153155757611,0.19054865591249434,2.1039880520769403,0.38638510613707605,2.199402700232554,-0.24316559991811548,0.6866990592950521,-0.5745330198140897,0.13386805297961285,0.6327337919013768,0.27495414250230754,-0.33242471265450957,-0.21360297580762733,2.223153155757611,-0.8223... | 3,375 |
FDA approved drug targets | 17 | 126 | 2.868707 | 0.004122 | P00813,P23786,Q13423,Q16739,P49721,Q13464,P48735,Q16836,P12235,P38435,P30084,Q16850,P50416,Q14145,P28074,O75874,P03886 | Drugs and Diseases | Protein Atlas Disease involvement | protein_atlas_disease_involvement | 0,34,262,133,40,104,11,15,143,174,204,82,266,182,238,95,31 | 1429,1370,750,2577,1260,95,2923,1768,1896,1438,450,2857,1839,0,3236,31,661,2825,2712,1493,2179,2713,726,1174,1263,1118,2580,264,1771,1898,2301,903,1383,1631,2858,1266,633,143,1122,1496,904,3115,3041,950,1384,1840,519,2830,1037,1634,907,1444,803,2034,2184,2716,1123,1078,1842,1079,34,583,1566,2189,2120,238,2309,2954,204,... | 0.048211934796472365,0.07685003800728503,0.4691567512932392,-0.4830577925150717,0.13386805297961285,2.031985358818018,-0.7598800080904538,-0.09631286647900751,-0.15476681385717422,0.048211934796472365,0.7938228645047847,-0.6977474581428348,-0.1254926486793712,8.05927987366474,-1.5313475075418816,3.030593559630485,0.551... | 3,375 |
FDA approved drug targets | 17 | 126 | 2.868707 | 0.004122 | P00813,P23786,Q13423,Q16739,P49721,Q13464,P48735,Q16836,P12235,P38435,P30084,Q16850,P50416,Q14145,P28074,O75874,P03886 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 0,34,262,133,40,104,11,15,143,174,204,82,266,182,238,95,31 | 1429,1370,750,2577,1260,95,2923,1768,1896,1438,450,2857,1839,0,3236,31,661,2825,2712,1493,2179,2713,726,1174,1263,1118,2580,264,1771,1898,2301,903,1383,1631,2858,1266,633,143,1122,1496,904,3115,3041,950,1384,1840,519,2830,1037,1634,907,1444,803,2034,2184,2716,1123,1078,1842,1079,34,583,1566,2189,2120,238,2309,2954,204,... | 0.048211934796472365,0.07685003800728503,0.4691567512932392,-0.4830577925150717,0.13386805297961285,2.031985358818018,-0.7598800080904538,-0.09631286647900751,-0.15476681385717422,0.048211934796472365,0.7938228645047847,-0.6977474581428348,-0.1254926486793712,8.05927987366474,-1.5313475075418816,3.030593559630485,0.551... | 3,375 |
Cerebral visual impairment | 18 | 69 | 2.856762 | 0.00428 | Q96RR1,Q9H2M9,P37268,P53007,Q96S52,Q08J23,Q9C0D9,Q9NUQ7,P00403,P12235,P08243,Q96CU9,Q4G0N4,Q9H490,Q9UID3,Q9UBB6,Q86YH6,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 219,466,521,227,273,41,106,575,494,143,518,86,23,221,423,549,370,31 | 2019,1028,2415,1556,2920,494,31,518,143,2304,2365,1217,2989,1567,1704,521,1708,1336,2957,227,1575,2128,998,1793,1794,1795,1049,41,1652,2725,1655,1984,1590,2140,23,2141,1664,2561,370,2730,589,2845,1096,2346,1201,968,86,2461,2513,1938,1151,1405,219,273,1297,106,466,2889,221,2091,2006,575,2778,1683,549,423,1108,894,694 | -0.21360297580762733,0.27495414250230754,-0.39240070950050854,-0.009327790283860563,-0.7598800080904538,0.7403936172598823,3.030593559630485,0.713579835070738,1.6412063989989234,-0.33242471265450957,-0.36236611826561227,0.16225002844017103,-0.82235748271142,-0.009327790283860563,-0.0672262509964336,0.713579835070738,-0... | 3,375 |
Regulation of leukocyte proliferation | 7 | 25 | 2.855916 | 0.004291 | P00813,P49366,P14174,Q9HCL2,Q16512,P17931,P30825 | Processes and pathways | GO Biological process | msigdb_gobp | 0,130,101,158,307,305,26 | 2857,0,3236,2825,318,1628,2031,101,1269,305,1387,2189,2309,26,1179,729,130,2550,2132,1089,307,1012,504,1817,158 | -0.6977474581428348,8.05927987366474,-1.5313475075418816,-0.6668117578076647,1.004988400356168,-0.038231613171792155,-0.21360297580762733,1.983768672818817,0.13386805297961285,1.031106974534266,0.07685003800728503,-0.2728238448155597,-0.33242471265450957,3.164753514554234,0.19054865591249434,0.49659904864423754,1.76459... | 3,375 |
Metabolism of vitamins and cofactors | 12 | 50 | 2.852641 | 0.004336 | P09455,Q6NUM9,P41440,Q9BQG2,P43490,Q8NFF5,Q96EY8,Q4G0N4,Q9NVE7,Q9H2D1,Q86YH6,O75874 | Processes and pathways | Reactome Pathways | msigdb_reactome | 319,348,321,274,14,272,48,23,289,29,370,95 | 1687,1429,898,1321,95,2950,631,1438,725,2113,602,2030,319,1900,2115,1965,1385,1842,2955,1331,2835,321,14,1041,1336,1647,2442,1716,23,348,2216,370,2342,2878,272,647,2001,48,2082,570,274,29,1481,420,1681,785,289,2619,2917,3078 | -0.0672262509964336,0.048211934796472365,0.358643578170959,0.10540172980990664,2.031985358818018,-0.7910758719515134,0.5784922208777676,0.048211934796472365,0.49659904864423754,-0.24316559991811548,0.6056479018936,-0.21360297580762733,1.004988400356168,-0.15476681385717422,-0.24316559991811548,-0.18413660636999382,0.07... | 3,375 |
Protein transmembrane transport | 10 | 28 | 2.84721 | 0.00441 | Q99595,O60830,Q15388,O95831,P50542,P49755,Q15629,Q3ZCQ8,Q9NS69,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 64,4,37,449,606,636,211,437,27,154 | 1216,1886,2666,4,3097,1891,449,1696,2181,1631,154,636,606,2129,2203,2257,1281,37,211,437,2068,1814,1098,2083,64,1308,27,688 | 0.16225002844017103,-0.15476681385717422,-0.5439512892731678,5.415645674566234,-1.0118216311731156,-0.15476681385717422,0.7938228645047847,-0.0672262509964336,-0.2728238448155597,-0.038231613171792155,1.5665946676492313,0.5784922208777676,0.6056479018936,-0.24316559991811548,-0.2728238448155597,-0.3025770869123972,0.13... | 3,375 |
Anion transmembrane transport | 14 | 45 | 2.840704 | 0.004501 | Q9UBX3,Q13546,Q9Y4C2,P53007,P41440,O95563,Q9UHG3,P12235,O60831,Q8TDW0,P08195,P30825,Q9H2D1,Q8TB61 | Processes and pathways | GO Biological process | msigdb_gobp | 400,528,599,227,321,302,13,143,514,312,252,26,29,546 | 628,1491,514,1693,1436,302,1174,1263,2894,252,143,1122,700,26,321,1847,1183,227,1916,2128,1509,2205,528,2386,2903,1595,2335,1525,546,312,2735,2848,29,1479,2353,1481,849,400,13,1750,857,2619,599,1423,1685 | 0.5784922208777676,0.019486354875994212,0.713579835070738,-0.0672262509964336,0.048211934796472365,1.031106974534266,0.19054865591249434,0.13386805297961285,-0.7287703736920425,1.1608155122181425,1.6412063989989234,0.21876491453847344,0.5239685462529114,3.164753514554234,1.004988400356168,-0.1254926486793712,0.19054865... | 3,375 |
Protein hydroxylation | 7 | 17 | 2.826904 | 0.0047 | Q32P28,O15460,P13674,O75718,Q92791,Q96AY3,Q8N543 | Processes and pathways | GO Biological process | msigdb_gobp | 65,74,76,78,56,124,123 | 280,74,859,78,1264,76,1455,1797,874,65,2907,123,56,124,650,592,2778 | 1.0831656426328216,2.223153155757611,0.38638510613707605,2.199402700232554,0.13386805297961285,2.223153155757611,0.048211934796472365,-0.09631286647900751,0.38638510613707605,2.341300334418682,-0.7287703736920425,1.8136162149972994,2.4584637978137454,1.8136162149972994,0.5784922208777676,0.6327337919013768,-0.605204024... | 3,375 |
Regulation of immune response | 38 | 126 | 2.806521 | 0.005008 | P00813,Q12846,P12956,O43657,Q99497,Q96PK6,Q9UKG1,Q92890,Q9NUD5,Q9Y4E8,Q9NPR9,Q9UHD2,Q96BN8,Q9Y3Z3,Q14671,Q14699,Q16512,P17931,P28070,Q9BUI4,Q9UIV1,Q07666,Q7Z434,P04439,Q8ND56,P41440,P46379,Q9NR50,Q12933,Q7KZ85,P49770,Q9NZ08,Q9NQC3,Q9NRA0,Q7Z739,Q96EP0,Q86UT6,P51812 | Processes and pathways | GO Biological process | msigdb_gobp | 0,527,8,384,20,681,152,150,685,425,159,689,417,692,295,412,307,305,556,189,190,434,196,318,462,321,453,624,96,611,604,103,230,109,501,374,241,239 | 1834,1428,2781,2984,384,1374,2482,1889,3039,2027,1891,900,1173,1895,0,3236,2825,318,2030,2180,1628,993,1899,2181,1631,3327,8,1267,2304,305,1701,1841,952,1387,2424,2038,556,2309,2426,3174,756,321,956,865,1127,2585,453,604,2316,831,239,1275,2959,2683,1648,2550,2056,671,434,1229,2996,527,2502,96,1717,873,2764,1854,1855,31... | -0.1254926486793712,0.048211934796472365,-0.6359637761900813,-0.82235748271142,0.873480632258922,0.07685003800728503,-0.42252790140681873,-0.15476681385717422,-0.9167120699523604,-0.21360297580762733,-0.15476681385717422,0.358643578170959,0.19054865591249434,-0.15476681385717422,8.05927987366474,-1.5313475075418816,-0.... | 3,375 |
Organic anion transmembrane transporter activity | 8 | 33 | 2.793027 | 0.005222 | P53007,P41440,O95563,P12235,Q6KCM7,P08195,P30825,Q9H2D1 | Functions | GO Molecular function | msigdb_gomf | 227,321,302,143,311,252,26,29 | 2104,628,1491,1693,302,1174,252,1900,143,1122,26,321,227,1916,2205,2386,1595,311,2600,2267,1525,546,2735,2848,29,1479,2353,1481,400,1750,2619,1423,1685 | -0.24316559991811548,0.5784922208777676,0.019486354875994212,-0.0672262509964336,1.031106974534266,0.19054865591249434,1.1608155122181425,-0.15476681385717422,1.6412063989989234,0.21876491453847344,3.164753514554234,1.004988400356168,1.2379520800421246,-0.15476681385717422,-0.2728238448155597,-0.36236611826561227,-0.00... | 3,375 |
Carbohydrate biosynthetic process | 11 | 47 | 2.779673 | 0.005441 | P49841,P11310,Q04446,Q9UBX3,P53007,Q92520,P13807,Q93009,Q8NCH0,Q9BYT8,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 32,1,261,400,227,172,167,443,185,57,154 | 1367,1372,2527,1693,1694,2244,1699,1,1120,2115,167,3009,2830,1902,907,154,1568,2493,757,1130,805,32,1642,227,2796,997,2836,2377,1793,432,261,2899,2766,1135,1051,3148,1727,185,172,443,1402,1202,57,2737,2979,400,1750 | 0.07685003800728503,0.07685003800728503,-0.45274711809482365,-0.0672262509964336,-0.0672262509964336,-0.3025770869123972,-0.0672262509964336,7.367385577094042,0.21876491453847344,-0.24316559991811548,1.491534732272122,-0.8537243644783261,-0.6668117578076647,-0.15476681385717422,0.358643578170959,1.5665946676492313,-0.0... | 3,375 |
Fatty acid catabolic process | 12 | 43 | 2.777313 | 0.005481 | P11310,P42126,P23786,O75521,P35610,Q16836,O14734,P30084,P50416,Q9BWD1,Q9UKG9,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 1,408,34,132,407,15,237,204,266,88,160,154 | 428,1687,898,237,1371,1491,132,2113,602,1771,1,2630,2118,34,2368,1446,1218,204,154,407,2678,2122,408,1571,2756,266,606,1975,2758,3068,737,1519,1051,15,2267,2931,3279,2076,2974,88,3169,822,160 | 0.8204396326290617,-0.0672262509964336,0.358643578170959,1.1865840591524877,0.07685003800728503,0.019486354875994212,1.7400097763933111,-0.24316559991811548,0.6056479018936,-0.09631286647900751,7.367385577094042,-0.5134593662434148,-0.24316559991811548,2.985614892363513,-0.36236611826561227,0.048211934796472365,0.16225... | 3,375 |
Fatty acid transport | 6 | 17 | 2.773583 | 0.005544 | O43772,P23786,P14174,P50416,Q9UKG9,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 33,34,101,266,160,154 | 898,33,1491,2243,2485,2825,1963,319,1900,101,34,1218,154,955,266,2267,160 | 0.358643578170959,3.0081206146023467,0.019486354875994212,-0.3025770869123972,-0.42252790140681873,-0.6668117578076647,-0.18413660636999382,1.004988400356168,-0.15476681385717422,1.983768672818817,2.985614892363513,0.16225002844017103,1.5665946676492313,0.33082515613705404,1.1091068208502726,-0.3025770869123972,1.56659... | 3,375 |
Immune response regulating signaling pathway | 19 | 61 | 2.773547 | 0.005545 | P00813,O43657,Q9UKG1,Q92890,Q9Y4E8,Q9NPR9,Q96BN8,Q14671,Q14699,Q16512,P17931,Q07666,Q8ND56,P04439,P41440,Q9NQC3,Q96EP0,Q86UT6,P51812 | Processes and pathways | GO Biological process | msigdb_gobp | 0,384,152,150,425,159,417,295,412,307,305,434,462,318,321,230,374,241,239 | 1834,1428,2984,384,1889,2027,1173,0,318,1628,1899,2181,2304,305,1841,1387,2309,2426,756,321,2585,453,604,2316,239,2683,2550,671,434,2996,1717,873,2764,1855,3156,1656,295,412,307,3167,1461,706,241,462,2694,150,417,374,1817,3137,2817,2351,159,230,624,685,3299,1749,1485,152,425 | -0.1254926486793712,0.048211934796472365,-0.82235748271142,0.873480632258922,-0.15476681385717422,-0.21360297580762733,0.19054865591249434,8.05927987366474,1.004988400356168,-0.038231613171792155,-0.15476681385717422,-0.2728238448155597,-0.33242471265450957,1.031106974534266,-0.1254926486793712,0.07685003800728503,-0.3... | 3,375 |
Tclin | 14 | 89 | 2.750941 | 0.005942 | P00813,P49841,Q13885,Q16739,P49721,Q13464,O43678,P48735,P38435,O43676,Q14145,P28074,P07437,P03886 | Drugs and Diseases | Pharos IDG Category | pharos_protein_category | 0,32,161,133,40,104,291,11,174,177,182,238,264,31 | 2103,2665,177,291,2577,1690,581,2241,493,1172,901,1695,1438,450,2857,0,31,661,1493,2179,2628,726,1263,3269,264,2301,903,1495,1383,2828,1631,2858,1266,633,1496,1840,2830,2953,803,2184,1078,1079,583,2424,1566,238,2584,1970,1220,1500,174,1846,11,40,2956,805,32,475,1573,1710,2128,2682,346,1280,2799,872,1186,834,104,808,161... | -0.24316559991811548,-0.5439512892731678,1.441240326714265,1.057165873125376,-0.4830577925150717,-0.0672262509964336,0.6327337919013768,-0.3025770869123972,0.7403936172598823,0.19054865591249434,0.358643578170959,-0.0672262509964336,0.048211934796472365,0.7938228645047847,-0.6977474581428348,8.05927987366474,3.03059355... | 3,375 |
Ragged red muscle fibers | 7 | 18 | 2.745534 | 0.006041 | Q96RR1,P00846,O95831,P12235,Q70HW3,Q9H2D1,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 219,260,449,143,188,29,31 | 1763,630,449,494,260,31,143,1219,1709,1575,1087,188,1867,219,1408,29,2235,2851 | -0.09631286647900751,0.5784922208777676,0.7938228645047847,0.7403936172598823,1.1349899370587961,3.030593559630485,1.6412063989989234,0.16225002844017103,-0.0672262509964336,-0.009327790283860563,0.24689976348114367,1.39073841091754,-0.1254926486793712,1.2635525405656844,0.07685003800728503,3.1201613747468726,-0.272823... | 3,375 |
Abnormal circulating protein concentration | 32 | 164 | 2.736783 | 0.006204 | Q8N511,P11310,Q969X5,Q9HC07,Q16836,P12235,Q8NFF5,Q96MW5,Q9UKG1,P50416,Q96BN8,O43772,P23786,Q5JRX3,Q08J23,Q96RL7,O75879,Q9BPX6,P46020,P41440,O95831,Q9BUK6,Q9NWM8,Q15120,Q96RR1,P14174,Q15056,Q9Y5L0,O14979,Q9Y487,Q9BT22,Q86YH6 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 256,1,135,139,15,143,272,418,152,266,417,33,34,296,41,51,181,465,192,321,449,79,83,90,219,101,233,382,110,250,376,370 | 1686,944,697,3242,110,2527,1626,33,1377,2920,659,1763,630,181,1766,1894,449,1173,1896,3079,1697,2487,1770,2536,902,1383,2302,1,143,101,3025,663,2582,2246,1776,603,2187,34,1219,830,2194,1179,2676,1568,2542,1181,2493,1448,2122,321,1221,1039,956,911,192,2371,2756,605,266,1222,1572,2957,1225,1916,1575,1786,2758,2050,2376,2... | -0.0672262509964336,0.33082515613705404,0.5239685462529114,-1.5644818109642689,1.9111150023933372,-0.45274711809482365,-0.038231613171792155,3.0081206146023467,0.07685003800728503,-0.7598800080904538,0.5512660173470204,-0.09631286647900751,0.5784922208777676,1.416015523904057,-0.09631286647900751,-0.15476681385717422,0... | 3,375 |
Abnormality of the mitochondrion | 18 | 101 | 2.735943 | 0.00622 | P11310,O43772,P23786,O75880,Q96RR1,P00846,P35637,Q9Y2R0,Q4J6C6,O43678,Q16836,P12235,P30084,O43676,Q96CU9,Q4G0N4,Q70HW3,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,33,34,129,219,260,320,363,393,291,15,143,204,177,86,23,188,31 | 697,897,2103,177,291,33,1690,581,2241,630,129,901,1695,494,260,31,3142,1326,2114,1772,1,143,2986,2630,2953,827,1329,2489,34,1566,2584,204,1219,320,1569,2678,2122,1640,911,757,2756,2956,606,1572,1573,3183,1709,1575,2318,1786,2682,1508,1509,2867,1853,2446,3205,1519,2212,15,437,23,393,1866,188,2142,1992,2729,2933,2563,317... | 0.5239685462529114,0.358643578170959,-0.24316559991811548,1.441240326714265,1.057165873125376,3.0081206146023467,-0.0672262509964336,0.6327337919013768,-0.3025770869123972,0.5784922208777676,1.7645918959276166,0.358643578170959,-0.0672262509964336,0.7403936172598823,1.1349899370587961,3.030593559630485,-1.1076741576662... | 3,375 |
Myalgia | 8 | 43 | 2.735489 | 0.006229 | P11310,P23786,P46020,Q9NZ08,O15460,P12235,Q9BUK6,Q92890 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,34,192,103,74,143,79,150 | 537,897,1257,74,945,1896,2244,3079,1697,3269,1,143,2989,1078,34,953,1219,1179,2122,956,192,1041,2756,1222,1572,608,1575,1786,2758,2261,1090,1459,2395,3259,442,150,1402,417,219,79,819,103,1953 | 0.6866990592950521,0.358643578170959,0.13386805297961285,2.223153155757611,0.33082515613705404,-0.15476681385717422,-0.3025770869123972,-0.980035309228183,-0.0672262509964336,-1.7312845351077755,7.367385577094042,1.6412063989989234,-0.82235748271142,0.24689976348114367,2.985614892363513,0.33082515613705404,0.1622500284... | 3,375 |
Small molecule catabolic process | 27 | 118 | 2.732988 | 0.006276 | P00813,P11310,O75521,Q16836,Q99497,P50416,Q9HCC0,Q9UKG9,P31751,P42126,P23786,P35610,Q13126,Q8IYS1,Q13867,Q8WTV0,Q16762,Q00796,P30837,A1L0T0,Q8TD30,P43304,P30084,O75600,Q9BWD1,Q9NX62,O14734 | Processes and pathways | GO Biological process | msigdb_gobp | 0,1,132,15,20,266,420,160,154,408,34,407,43,439,46,50,308,432,55,428,326,200,204,448,88,215,237 | 428,1687,898,237,1371,3059,1168,1491,132,448,1693,2242,1627,1262,2857,2485,0,1897,1322,726,2113,602,2361,1561,1771,992,1326,1035,2363,1,1075,2630,3009,3243,663,1902,1077,1217,1635,2118,828,34,2368,1703,1446,1218,953,204,55,154,1273,2955,1331,407,1569,3374,2427,2678,2122,408,1571,200,1040,1503,2756,805,1336,266,606,2048... | 0.8204396326290617,-0.0672262509964336,0.358643578170959,1.1865840591524877,0.07685003800728503,-0.948331973940958,0.19054865591249434,0.019486354875994212,1.7400097763933111,0.7938228645047847,-0.0672262509964336,-0.3025770869123972,-0.038231613171792155,0.13386805297961285,-0.6977474581428348,-0.42252790140681873,8.0... | 3,375 |
Abnormality of the female genitalia | 32 | 131 | 2.731534 | 0.006304 | Q16740,P48735,Q15392,O00170,Q9BXW9,P24468,Q92890,P31751,O00192,O75312,Q08J23,O95155,Q92766,Q14145,P63167,Q01844,Q9H2M9,Q6KC79,Q9NR50,O75874,Q96RR1,O75844,P49770,O43683,Q15056,P50542,O15360,Q5JTZ9,Q15427,P51812,P53701,Q8WWQ0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 9,11,12,512,419,520,150,154,537,404,41,42,442,182,323,561,466,456,624,95,219,471,604,470,233,606,115,499,497,239,253,126 | 944,512,537,2945,1761,115,1028,470,1837,2666,1554,1378,3114,1492,1116,2416,404,2947,2948,471,95,3198,42,2029,2669,724,1895,3079,1322,3099,2748,2031,1075,994,1903,1329,1078,2489,520,1970,1567,154,2039,1179,2676,667,2677,1081,865,11,1041,604,2201,606,2048,831,239,1042,253,608,1575,2721,2050,868,323,2637,2260,561,2500,205... | 0.33082515613705404,0.713579835070738,0.6866990592950521,-0.7910758719515134,-0.09631286647900751,1.862456329832627,0.27495414250230754,0.7671410746721091,-0.1254926486793712,-0.5439512892731678,-0.009327790283860563,0.07685003800728503,-1.04369050099163,0.019486354875994212,0.21876491453847344,-0.39240070950050854,0.8... | 3,375 |
Abnormality of cardiovascular system electrophysiology | 18 | 114 | 2.727581 | 0.00638 | P11310,O43772,P23786,O75880,Q96RR1,P00846,Q6PJG6,O15460,Q15056,Q16836,P12235,Q02487,Q03001,Q9Y4P8,Q8NFF5,Q9H490,P53701,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,33,34,129,219,260,201,74,233,15,143,80,17,251,272,221,253,31 | 2019,74,3231,33,385,2666,3161,1321,581,3039,826,129,800,754,2112,494,260,3079,31,1962,1697,1322,948,2113,602,3269,2487,2924,1560,2748,1325,2536,1495,1383,1,143,2859,3025,495,1329,34,520,1219,2676,1569,2542,1181,2493,2427,1448,1081,2719,2122,1911,1912,757,2371,2756,605,266,606,3282,1573,3183,253,1575,2758,2896,2377,2637... | -0.21360297580762733,2.223153155757611,-1.4653079613874214,3.0081206146023467,0.873480632258922,-0.5439512892731678,-1.1719828815512887,0.10540172980990664,0.6327337919013768,-0.9167120699523604,0.41405059073486755,1.7645918959276166,0.44164086630862914,0.4691567512932392,-0.24316559991811548,0.7403936172598823,1.13498... | 3,375 |
Cellular carbohydrate metabolic process | 16 | 66 | 2.719886 | 0.00653 | Q9UNI6,P11310,Q04446,P49841,P46020,Q15120,Q92520,P43304,P48735,P13807,Q93009,Q9BYT8,Q9NX62,P31751,Q9Y6N1,O75874 | Processes and pathways | GO Biological process | msigdb_gobp | 402,1,261,32,192,90,172,200,11,167,443,57,215,154,427,95 | 1367,1687,1372,2527,2531,1693,471,95,1627,1322,1324,632,1561,1383,802,1,167,3243,1902,2715,1217,154,1568,3211,200,192,757,11,1130,805,32,2048,3282,1642,917,2796,997,2836,2377,432,2898,261,999,2899,585,3195,3104,90,2766,1135,1051,3148,3167,1727,172,443,1402,1202,57,2737,2007,2613,215,402,720,427 | 0.07685003800728503,-0.0672262509964336,0.07685003800728503,-0.45274711809482365,-0.45274711809482365,-0.0672262509964336,0.7671410746721091,2.031985358818018,-0.038231613171792155,0.10540172980990664,0.10540172980990664,0.5784922208777676,-0.009327790283860563,0.07685003800728503,0.44164086630862914,7.367385577094042,... | 3,375 |
Carbohydrate metabolic process | 21 | 142 | 2.71792 | 0.006569 | P11310,Q04446,P48735,P31751,P49841,Q92520,P13807,Q8NBZ7,Q8NCH0,Q9BYT8,P30837,P46020,P43304,Q6PJG6,Q9NX62,Q15120,O75874,P53007,Q9BRR6,Q9H488,P08195 | Processes and pathways | GO Biological process | msigdb_gobp | 1,261,11,154,32,172,167,45,185,57,55,192,200,201,215,90,95,227,118,121,252 | 1367,697,3112,1687,1372,3038,2527,554,3268,2531,2625,1693,471,95,2418,1892,1694,1627,1896,2244,1769,1697,2712,1322,2713,726,3269,2361,1324,1699,1382,1118,3329,252,632,1561,3142,1074,1383,2114,1900,1772,802,1,1120,2115,167,3009,1773,2830,3243,1902,1077,2116,2715,1217,907,55,154,3219,2194,1568,2369,2493,2677,3211,1502,27... | 0.07685003800728503,0.5239685462529114,-1.04369050099163,-0.0672262509964336,0.07685003800728503,-0.9167120699523604,-0.45274711809482365,0.6597506092154378,-1.7312845351077755,-0.45274711809482365,-0.5134593662434148,-0.0672262509964336,0.7671410746721091,2.031985358818018,-0.39240070950050854,-0.15476681385717422,-0.... | 3,375 |
Negative regulation of response to external stimulus | 13 | 50 | 2.71309 | 0.006666 | P00813,P14174,P04439,Q9UMX5,Q86UT6,O43657,O14936,P80303,Q92890,Q96G23,Q8IXJ6,Q9Y4E8,Q9UIV1 | Processes and pathways | GO Biological process | msigdb_gobp | 0,101,318,89,241,384,383,22,150,54,372,425,190 | 383,384,2578,3039,2533,0,1962,318,2486,1631,101,1841,907,2424,556,2492,1781,3174,1127,2316,2128,1275,759,22,671,1854,1518,1348,3167,1396,501,2396,241,372,2694,150,417,54,1817,1013,1606,1015,848,3094,190,89,692,425,895,3292 | 0.873480632258922,0.873480632258922,-0.4830577925150717,-0.9167120699523604,-0.45274711809482365,8.05927987366474,-0.18413660636999382,1.004988400356168,-0.42252790140681873,-0.038231613171792155,1.983768672818817,-0.1254926486793712,0.358643578170959,-0.39240070950050854,0.6597506092154378,-0.42252790140681873,-0.0963... | 3,375 |
Sloping forehead | 16 | 49 | 2.709821 | 0.006732 | P23786,O43683,O95630,Q08J23,Q15003,Q9H267,Q86XL3,Q9H9E3,O14578,O14936,Q02224,P08243,Q9BXW9,Q6P4I2,Q96EK5,O15360 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 34,470,317,41,610,592,44,107,579,383,268,518,419,457,351,115 | 1686,579,383,115,1028,470,1837,1378,2416,317,518,34,1271,1704,2679,2199,1085,2050,761,1280,268,41,2442,1983,1654,610,1287,1928,3148,457,44,738,2730,1200,1353,1201,351,2081,3179,1297,419,592,1479,107,1481,2092,1821,655,2620 | -0.0672262509964336,0.6327337919013768,0.873480632258922,1.862456329832627,0.27495414250230754,0.7671410746721091,-0.1254926486793712,0.07685003800728503,-0.39240070950050854,1.004988400356168,0.713579835070738,2.985614892363513,0.13386805297961285,-0.0672262509964336,-0.5439512892731678,-0.2728238448155597,0.246899763... | 3,375 |
Lethargy | 10 | 84 | 2.708676 | 0.006755 | P11310,P23786,O43772,Q96RR1,Q16836,P12235,Q96EY8,O43676,Q96CU9,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,34,33,219,15,143,48,177,86,31 | 898,177,33,1690,581,2241,1695,31,2113,602,3142,1034,1326,1900,2363,1,143,2305,2953,827,1635,1842,828,34,1446,2584,1569,3174,2122,1911,2754,1040,2586,2045,2756,604,2956,266,1575,2758,2682,868,1131,1340,2926,2993,1789,1276,1645,3083,2546,2053,2057,1717,1855,1984,15,2933,2563,2730,3177,2810,86,48,2884,2082,219,2226,1479,1... | 0.358643578170959,1.441240326714265,3.0081206146023467,-0.0672262509964336,0.6327337919013768,-0.3025770869123972,-0.0672262509964336,3.030593559630485,-0.24316559991811548,0.6056479018936,-1.1076741576662066,0.27495414250230754,0.10540172980990664,-0.15476681385717422,-0.36236611826561227,7.367385577094042,1.641206398... | 3,375 |
Asthma | 9 | 22 | 2.705679 | 0.006816 | P00813,O00192,Q08J23,Q9UJV9,P50542,Q93009,Q92766,Q92890,Q9UID3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,537,41,577,606,443,442,150,423 | 537,1892,0,1565,3080,1078,2677,1846,606,1084,608,41,1004,2267,967,442,150,443,2159,1412,423,577 | 0.6866990592950521,-0.15476681385717422,8.05927987366474,-0.009327790283860563,-0.980035309228183,0.24689976348114367,-0.5439512892731678,-0.1254926486793712,0.6056479018936,0.24689976348114367,0.6056479018936,2.7358317422764893,0.30292897251860446,-0.3025770869123972,0.33082515613705404,0.8204396326290617,1.6163849582... | 3,375 |
Calcium-binding protein | 9 | 20 | 2.702274 | 0.006887 | Q02818,Q9BPX6,P43307,Q15293,Q14257,Q9BRK5,P80303,O43852,P41208 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 324,465,102,335,16,213,22,85,216 | 85,1495,665,1910,216,102,2635,2722,22,324,16,335,1724,2603,502,1813,3228,465,213,2474 | 2.1039880520769403,0.019486354875994212,0.5512660173470204,-0.15476681385717422,1.2635525405656844,1.983768672818817,-0.5134593662434148,-0.5745330198140897,3.429711270359728,1.004988400356168,3.7764352379093236,0.978809595175081,-0.0672262509964336,-0.4830577925150717,0.7403936172598823,-0.09631286647900751,-1.4324034... | 3,375 |
Leukocyte proliferation | 7 | 38 | 2.691749 | 0.007108 | P00813,P49366,P14174,Q9HCL2,Q16512,P17931,P30825 | Processes and pathways | GO Biological process | msigdb_gobp | 0,130,101,158,307,305,26 | 2857,1839,0,3236,1962,2825,318,1322,1628,2031,2181,1496,101,1269,905,305,1387,2717,2189,2309,26,1781,1179,729,130,3013,1510,2550,2132,1089,307,2345,1012,504,1817,158,1157,689 | -0.6977474581428348,-0.1254926486793712,8.05927987366474,-1.5313475075418816,-0.18413660636999382,-0.6668117578076647,1.004988400356168,0.10540172980990664,-0.038231613171792155,-0.21360297580762733,-0.2728238448155597,0.019486354875994212,1.983768672818817,0.13386805297961285,0.358643578170959,1.031106974534266,0.0768... | 3,375 |
Alcohol metabolic process | 22 | 81 | 2.680644 | 0.007348 | Q9Y394,P48735,Q15392,Q99497,P35610,P51648,Q8WTV0,Q00796,P30837,Q9H2C2,P43304,O94788,Q9BY49,Q16850,Q9NX62,Q6NUM9,Q96PE3,O75874,Q15800,Q14534,Q9NRA0,O15269 | Processes and pathways | GO Biological process | msigdb_gobp | 535,11,12,20,407,410,50,432,55,66,200,75,203,82,215,348,94,95,234,356,109,490 | 1367,627,490,1113,2529,2920,2711,95,75,2298,1627,1438,725,661,1962,2713,726,992,1120,1075,1840,3009,2830,994,1902,907,2489,55,2835,407,521,1571,200,3100,11,2756,1784,2048,3282,410,1976,2495,2796,1712,3238,2498,432,2866,2898,999,673,3366,585,1719,356,1459,1858,2690,12,1987,234,1051,82,3167,348,2846,647,50,94,20,1941,101... | 0.07685003800728503,0.5784922208777676,0.7403936172598823,0.21876491453847344,-0.45274711809482365,-0.7598800080904538,-0.5745330198140897,2.031985358818018,2.223153155757611,-0.33242471265450957,-0.038231613171792155,0.048211934796472365,0.49659904864423754,0.5512660173470204,-0.18413660636999382,-0.5745330198140897,0... | 3,375 |
Tetrapyrrole binding | 8 | 16 | 2.677206 | 0.007424 | Q9H7Z7,Q96EY8,O43169,Q16850,P30519,P53701,Q6UW02,O15173 | Functions | GO Molecular function | msigdb_gomf | 572,48,116,82,24,253,58,489 | 1317,489,116,1265,993,1842,24,253,82,58,2142,48,570,572,2282,2917 | 0.10540172980990664,0.7403936172598823,1.862456329832627,0.13386805297961285,0.30292897251860446,-0.1254926486793712,3.2756861538715345,1.1608155122181425,2.1279042192938276,2.435108227632791,-0.24316559991811548,2.6439590132330637,0.6597506092154378,0.6597506092154378,-0.3025770869123972,-0.7287703736920425 | 3,375 |
Peripheral axonal neuropathy | 22 | 61 | 2.670217 | 0.00758 | Q04446,Q8IV08,P00846,P12235,Q96MW5,P03886,Q9Y4W6,Q96RL7,Q15813,P07384,Q9BPX6,O00330,O95831,Q5TAQ9,O95140,Q15067,Q96BR5,Q96RR1,Q9H0B6,P22626,P00403,O15269 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 261,3,260,143,418,31,578,51,435,68,465,697,449,77,331,737,619,219,360,603,494,490 | 697,490,1113,1377,945,2415,2110,331,449,494,260,31,1770,68,2924,1325,902,143,1217,603,1904,1331,3211,1335,2375,1222,1575,1576,1786,1578,1455,261,1652,2442,1654,1655,2446,737,1593,435,77,3226,2395,3,2648,3259,3271,619,2771,418,51,219,465,1058,360,1481,2659,746,2093,578,2823 | 0.5239685462529114,0.7403936172598823,0.21876491453847344,0.07685003800728503,0.33082515613705404,-0.39240070950050854,-0.24316559991811548,0.978809595175081,0.7938228645047847,0.7403936172598823,1.1349899370587961,3.030593559630485,-0.09631286647900751,2.294161378716793,-0.7598800080904538,0.10540172980990664,0.358643... | 3,375 |
Monocarboxylic acid catabolic process | 12 | 46 | 2.664065 | 0.00772 | P11310,P42126,P23786,O75521,P35610,Q16836,O14734,P30084,P50416,Q9BWD1,Q9UKG9,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 1,408,34,132,407,15,237,204,266,88,160,154 | 428,1687,898,237,1371,1491,132,2113,602,1771,1,2630,3009,663,2118,34,2368,1446,1218,204,154,407,2678,2122,408,1571,2756,266,606,1975,1642,2758,3068,737,1519,1051,15,2267,2931,3279,2076,2974,88,3169,822,160 | 0.8204396326290617,-0.0672262509964336,0.358643578170959,1.1865840591524877,0.07685003800728503,0.019486354875994212,1.7400097763933111,-0.24316559991811548,0.6056479018936,-0.09631286647900751,7.367385577094042,-0.5134593662434148,-0.8537243644783261,0.5512660173470204,-0.24316559991811548,2.985614892363513,-0.3623661... | 3,375 |
Metalloprotease | 11 | 27 | 2.650753 | 0.008031 | Q5JRX3,Q9NQH7,O75844,P55786,O95630,Q9Y4W6,Q9NZ08,O43847,Q7Z2K6,P14735,Q9BYT8 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 296,263,471,7,317,578,103,386,638,519,57 | 1835,386,947,471,3163,317,860,1565,519,1912,2256,7,296,676,638,2000,2225,2464,1356,57,1676,263,1105,1158,103,1826,578 | -0.1254926486793712,0.873480632258922,0.33082515613705404,0.7671410746721091,-1.1719828815512887,1.004988400356168,0.38638510613707605,-0.009327790283860563,0.713579835070738,-0.15476681385717422,-0.3025770869123972,4.918525847007338,1.057165873125376,0.5512660173470204,0.5784922208777676,-0.18413660636999382,-0.272823... | 3,375 |
Organic acid catabolic process | 19 | 85 | 2.644458 | 0.008182 | P11310,O75521,Q16836,P50416,Q9HCC0,Q9UKG9,P31751,P42126,P23786,P35610,Q8IYS1,Q13867,Q16762,A1L0T0,Q8TD30,P30084,O75600,Q9BWD1,O14734 | Processes and pathways | GO Biological process | msigdb_gobp | 1,132,15,266,420,160,154,408,34,407,439,46,308,428,326,204,448,88,237 | 428,1687,898,237,1371,3059,1168,1491,132,448,2242,1262,2485,1897,2113,602,1771,992,1326,2363,1,2630,3009,663,1902,1635,2118,828,34,2368,1703,1446,1218,953,204,154,1273,2955,1331,407,1569,2427,2678,2122,408,1571,1040,1503,2756,1336,266,606,475,1975,1642,702,2758,2960,3068,46,737,1519,308,1051,15,3347,1866,2267,1465,2931... | 0.8204396326290617,-0.0672262509964336,0.358643578170959,1.1865840591524877,0.07685003800728503,-0.948331973940958,0.19054865591249434,0.019486354875994212,1.7400097763933111,0.7938228645047847,-0.3025770869123972,0.13386805297961285,-0.42252790140681873,-0.15476681385717422,-0.24316559991811548,0.6056479018936,-0.0963... | 3,375 |
Nucleobase containing compound transmembrane transporter activity | 7 | 15 | 2.636865 | 0.008368 | P41440,P12235,Q9BSK2,Q6KCM7,Q9H2D1,Q8TB61,P51991 | Functions | GO Molecular function | msigdb_gomf | 321,143,18,311,29,546,560 | 1427,628,1491,1174,143,1122,321,560,311,2600,1525,546,18,29,1481 | 0.048211934796472365,0.5784922208777676,0.019486354875994212,0.19054865591249434,1.6412063989989234,0.21876491453847344,1.004988400356168,0.6597506092154378,1.031106974534266,-0.4830577925150717,0.019486354875994212,0.6866990592950521,3.6904267756578513,3.1201613747468726,0.048211934796472365 | 3,375 |
Abnormal muscle fiber morphology | 25 | 74 | 2.627783 | 0.008594 | P00846,O75648,P12235,Q9H2D1,P03886,P23786,O75190,Q9Y4W6,P13807,O43676,Q96RL7,Q70HW3,Q9BPX6,P35637,O95831,Q9BUK6,P61978,Q8NI60,Q96RR1,P53007,P22626,P50402,Q9Y5L0,O14979,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,630,143,29,31,34,659,578,167,177,51,188,465,320,449,79,345,93,219,227,603,605,382,110,494 | 2103,3242,110,177,1377,945,659,1763,630,449,1696,494,260,3079,31,1697,2713,2487,1770,1561,902,2302,143,167,1776,603,34,1219,830,320,1705,956,757,605,1222,731,227,1709,1575,1786,345,1455,1087,1853,1283,1655,1090,3205,1593,3157,188,2395,1992,1867,3259,93,1869,1870,51,219,3356,465,1408,1102,79,2280,29,937,720,2235,2098,57... | -0.24316559991811548,-1.5644818109642689,1.9111150023933372,1.441240326714265,0.07685003800728503,0.33082515613705404,0.5512660173470204,-0.09631286647900751,0.5784922208777676,0.7938228645047847,-0.0672262509964336,0.7403936172598823,1.1349899370587961,-0.980035309228183,3.030593559630485,-0.0672262509964336,-0.574533... | 3,375 |
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