term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abnormal circulating lipid concentration
| 13
| 75
| 2.625809
| 0.008644
|
Q8N511,P11310,O75880,O43772,P23786,Q15800,Q15056,Q9H9E3,Q15392,Q16836,P42858,Q4G0N4,P31751
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
256,1,129,33,34,234,233,107,12,15,175,23,154
|
1257,1626,33,2666,2297,630,471,129,1766,3079,3269,1324,2924,1326,1,909,34,556,1970,154,2676,1568,1569,521,3371,1081,2122,175,1335,730,2756,605,266,606,2048,1975,1643,2758,2050,3238,2637,2898,2500,2962,835,1654,1283,1459,233,12,1987,234,876,1003,15,23,2455,256,2343,1870,2147,1096,1102,819,107,746,2093,3006,2356,1881,1750,2982,1253,2917,382
|
0.13386805297961285,-0.038231613171792155,3.0081206146023467,-0.5439512892731678,-0.33242471265450957,0.5784922208777676,0.7671410746721091,1.7645918959276166,-0.09631286647900751,-0.980035309228183,-1.7312845351077755,0.10540172980990664,-0.7598800080904538,0.10540172980990664,7.367385577094042,0.358643578170959,2.985614892363513,0.6597506092154378,-0.18413660636999382,1.5665946676492313,-0.5439512892731678,-0.009327790283860563,-0.009327790283860563,0.713579835070738,-7.168005489173489,0.24689976348114367,-0.24316559991811548,1.4664132535336514,0.10540172980990664,0.49659904864423754,-0.6052040240979027,0.6056479018936,1.1091068208502726,0.6056479018936,-0.21360297580762733,-0.18413660636999382,-0.038231613171792155,-0.6052040240979027,-0.21360297580762733,-1.5313475075418816,-0.5134593662434148,-0.7287703736920425,-0.42252790140681873,-0.7910758719515134,0.41405059073486755,-0.038231613171792155,0.13386805297961285,0.048211934796472365,1.212296082730813,4.031896411144352,-0.18413660636999382,1.212296082730813,0.38638510613707605,0.30292897251860446,3.797869337859779,3.4077973078556516,-0.39240070950050854,1.1608155122181425,-0.33242471265450957,-0.1254926486793712,-0.24316559991811548,0.24689976348114367,0.24689976348114367,0.44164086630862914,1.9595949228824863,0.49659904864423754,-0.21360297580762733,-0.82235748271142,-0.33242471265450957,-0.1254926486793712,-0.0672262509964336,-0.7910758719515134,0.16225002844017103,-0.7287703736920425,0.8999061013249092
| 3,375
|
Immunity
| 24
| 79
| 2.610151
| 0.00905
|
Q8IV08,P12956,Q96PK6,Q9NUD5,Q9UHD2,Q96BN8,Q9Y3Z3,Q9UQ84,Q6P179,Q07021,P17931,Q9BUI4,Q7Z434,P04439,P46379,P10321,O43823,Q9UII4,P14174,Q9NZ08,Q03518,Q9BWS9,Q8IXJ6,Q86UT6
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
3,8,681,685,689,417,692,36,676,671,305,189,196,318,453,452,210,224,101,103,232,507,372,241
|
1428,3313,3021,1257,2622,210,2482,1889,900,1033,1173,2825,2712,318,1628,452,8,1267,101,905,305,1217,1386,952,2424,2038,756,956,453,1849,1275,1648,232,671,1229,1514,2688,2381,1853,1854,1656,1927,1518,1865,676,706,2601,196,1994,2396,241,3,372,2769,2567,776,1668,1147,2512,417,2151,1817,681,1607,932,189,507,1304,2912,685,3094,103,689,224,1107,3304,36,692,895
|
0.048211934796472365,-2.104720346998251,-0.8851760478860837,0.13386805297961285,-0.5134593662434148,1.2890979463364292,-0.42252790140681873,-0.15476681385717422,0.358643578170959,0.27495414250230754,0.19054865591249434,-0.6668117578076647,-0.5745330198140897,1.004988400356168,-0.038231613171792155,0.7938228645047847,4.85801582075318,0.13386805297961285,1.983768672818817,0.358643578170959,1.031106974534266,0.16225002844017103,0.07685003800728503,0.33082515613705404,-0.39240070950050854,-0.21360297580762733,0.4691567512932392,0.33082515613705404,0.7938228645047847,-0.1254926486793712,0.13386805297961285,-0.038231613171792155,1.212296082730813,0.5512660173470204,0.16225002844017103,0.019486354875994212,-0.5439512892731678,-0.36236611826561227,-0.1254926486793712,-0.1254926486793712,-0.038231613171792155,-0.15476681385717422,0.019486354875994212,-0.1254926486793712,0.5512660173470204,0.5239685462529114,-0.4830577925150717,1.3654085471612543,-0.18413660636999382,-0.36236611826561227,1.1865840591524877,5.727500366668169,0.8999061013249092,-0.6052040240979027,-0.45274711809482365,0.4691567512932392,-0.038231613171792155,0.21876491453847344,-0.42252790140681873,0.8469920138668321,-0.24316559991811548,-0.09631286647900751,0.5512660173470204,-0.009327790283860563,0.358643578170959,1.39073841091754,0.7403936172598823,0.13386805297961285,-0.7287703736920425,0.5512660173470204,-0.980035309228183,1.983768672818817,0.5512660173470204,1.2635525405656844,0.24689976348114367,-1.96791426020348,2.872587768674245,0.5512660173470204,0.38638510613707605
| 3,375
|
Vitamin binding
| 14
| 49
| 2.598796
| 0.009355
|
O00469,Q32P28,P09455,P41440,O15460,O94788,P13674,P38435,Q96EY8,Q8N543,O75600,A1L0T0,O15269,Q8TD30
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
280,65,319,321,74,75,76,174,48,123,448,428,490,326
|
428,280,1687,1429,490,1113,74,859,448,75,1766,1438,2485,1962,1897,1493,2113,1324,319,802,2115,76,1902,1842,828,1908,3255,2955,1331,174,321,1041,1336,1649,1455,65,1231,2691,1465,123,326,48,2082,570,2778,822,2917,2620,3078
|
0.8204396326290617,1.0831656426328216,-0.0672262509964336,0.048211934796472365,0.7403936172598823,0.21876491453847344,2.223153155757611,0.38638510613707605,0.7938228645047847,2.223153155757611,-0.09631286647900751,0.048211934796472365,-0.42252790140681873,-0.18413660636999382,-0.15476681385717422,0.019486354875994212,-0.24316559991811548,0.10540172980990664,1.004988400356168,0.44164086630862914,-0.24316559991811548,2.223153155757611,-0.15476681385717422,-0.1254926486793712,0.41405059073486755,-0.15476681385717422,-1.6643385894420446,-0.7910758719515134,0.10540172980990664,1.4664132535336514,1.004988400356168,0.27495414250230754,0.10540172980990664,-0.038231613171792155,0.048211934796472365,2.341300334418682,0.16225002844017103,-0.5439512892731678,0.048211934796472365,1.8136162149972994,1.004988400356168,2.6439590132330637,-0.21360297580762733,0.6597506092154378,-0.6052040240979027,0.44164086630862914,-0.7287703736920425,-0.4830577925150717,-0.948331973940958
| 3,375
|
Endoplasmic reticulum
| 55
| 193
| 2.581036
| 0.00985
|
Q8IV08,Q8NHH9,O95197,Q9NVZ3,Q96GC9,P27635,Q14257,O60831,O15260,P37268,Q9UGP8,O96005,P20810,O14967,P35610,P51648,P0CG08,Q86XL3,P27797,Q96CS3,Q96KC8,Q8TCT9,Q96G23,Q92791,Q70UQ0,Q86UE4,Q96PC5,Q96CN7,P30533,O15460,Q15293,P13674,Q9HCU5,Q9P2W9,Q16850,Q96F07,O43852,Q8NHP6,P84157,O43264,P00387,P43307,Q15800,Q9NQC3,Q4ZIN3,Q13217,Q03518,P50402,O15269,P51571,Q9C0E8,Q9BT22,O43169,Q8NF37,Q14696
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
3,398,259,277,136,635,16,514,19,521,688,283,405,281,407,410,662,44,665,566,569,564,54,56,183,197,463,73,701,74,335,76,336,84,82,740,85,613,734,723,725,102,234,230,105,477,232,605,490,607,377,376,116,645,368
|
1317,2237,281,1760,19,490,74,116,723,3023,85,2783,514,1492,2711,1436,1261,2298,259,2787,1766,283,725,1381,1323,2579,1263,1264,1561,1034,662,2302,2033,76,2987,1036,1966,1701,2537,2367,2307,405,1078,2749,1387,2833,635,665,1272,2791,910,701,2425,1704,407,3116,1501,521,1332,2754,102,2755,2586,2794,2633,2044,3277,2200,2253,730,605,2255,1914,607,2317,410,3315,2129,868,2319,1131,2320,2257,1919,2993,2684,1920,3203,1045,1276,2497,2437,2798,3013,1388,2379,1645,2259,1277,2131,2322,1580,1342,3014,2686,2323,734,1344,232,2057,1797,874,477,1983,809,16,1392,368,1134,2903,920,335,763,1987,234,764,82,105,2805,1005,1663,1523,2875,183,197,2067,44,2562,3,2648,2342,2269,1731,645,398,613,2398,564,2223,3252,56,2346,2148,2079,73,566,740,54,136,969,1671,569,463,1608,2083,2699,1942,1673,1298,376,2515,377,2657,1948,3367,1411,1206,336,230,1417,277,1683,1544,2011,1248,2287,84,2356,2469,688,3302,2742,2476
|
0.10540172980990664,-0.3025770869123972,1.0831656426328216,-0.09631286647900751,3.6688559426474816,0.7403936172598823,2.223153155757611,1.862456329832627,0.49659904864423754,-0.8851760478860837,2.1039880520769403,-0.6359637761900813,0.713579835070738,0.019486354875994212,-0.5745330198140897,0.048211934796472365,0.13386805297961285,-0.33242471265450957,1.1349899370587961,-0.6359637761900813,-0.09631286647900751,1.0831656426328216,0.49659904864423754,0.07685003800728503,0.10540172980990664,-0.4830577925150717,0.13386805297961285,0.13386805297961285,-0.009327790283860563,0.27495414250230754,0.5512660173470204,-0.33242471265450957,-0.21360297580762733,2.223153155757611,-0.82235748271142,0.27495414250230754,-0.18413660636999382,-0.0672262509964336,-0.45274711809482365,-0.36236611826561227,-0.33242471265450957,0.8469920138668321,0.24689976348114367,-0.6052040240979027,0.07685003800728503,-0.6668117578076647,0.5784922208777676,0.5512660173470204,0.13386805297961285,-0.6359637761900813,0.358643578170959,0.5239685462529114,-0.39240070950050854,-0.0672262509964336,0.8469920138668321,-1.04369050099163,0.019486354875994212,0.713579835070738,0.10540172980990664,-0.6052040240979027,1.983768672818817,-0.6052040240979027,-0.4830577925150717,-0.6359637761900813,-0.5134593662434148,-0.21360297580762733,-1.7985271289035507,-0.2728238448155597,-0.3025770869123972,0.49659904864423754,0.6056479018936,-0.3025770869123972,-0.15476681385717422,0.6056479018936,-0.33242471265450957,0.8469920138668321,-2.104720346998251,-0.24316559991811548,0.38638510613707605,-0.33242471265450957,0.21876491453847344,-0.33242471265450957,-0.3025770869123972,-0.15476681385717422,-0.82235748271142,-0.5439512892731678,-0.15476681385717422,-1.334155331699041,0.27495414250230754,0.13386805297961285,-0.42252790140681873,-0.39240070950050854,-0.6359637761900813,-0.8537243644783261,0.07685003800728503,-0.36236611826561227,-0.038231613171792155,-0.3025770869123972,0.13386805297961285,-0.24316559991811548,-0.33242471265450957,-0.009327790283860563,0.10540172980990664,-0.8537243644783261,-0.5439512892731678,-0.33242471265450957,0.49659904864423754,0.10540172980990664,1.212296082730813,-0.21360297580762733,-0.09631286647900751,0.38638510613707605,0.7671410746721091,-0.18413660636999382,0.44164086630862914,3.7764352379093236,0.07685003800728503,0.8999061013249092,0.21876491453847344,-0.7287703736920425,0.358643578170959,0.978809595175081,0.4691567512932392,-0.18413660636999382,1.212296082730813,0.4691567512932392,2.1279042192938276,1.9595949228824863,-0.6359637761900813,0.30292897251860446,-0.038231613171792155,0.019486354875994212,-0.6977474581428348,1.416015523904057,1.3654085471612543,-0.21360297580762733,2.689966750135784,-0.45274711809482365,5.727500366668169,-0.5134593662434148,-0.33242471265450957,-0.3025770869123972,-0.0672262509964336,0.5784922208777676,0.873480632258922,0.6056479018936,-0.36236611826561227,0.6597506092154378,-0.2728238448155597,-1.5976919926421527,2.4584637978137454,-0.33242471265450957,-0.24316559991811548,-0.21360297580762733,2.246862901123615,0.6597506092154378,0.49659904864423754,2.4817813149505383,1.6907038084850876,0.33082515613705404,-0.038231613171792155,0.6597506092154378,0.7938228645047847,-0.009327790283860563,-0.21360297580762733,-0.5439512892731678,-0.15476681385717422,-0.038231613171792155,0.13386805297961285,0.8999061013249092,-0.42252790140681873,0.8999061013249092,-0.5134593662434148,-0.15476681385717422,-4.321506834636257,0.07685003800728503,0.19054865591249434,0.978809595175081,1.2379520800421246,0.07685003800728503,1.1091068208502726,-0.038231613171792155,0.019486354875994212,-0.18413660636999382,0.16225002844017103,-0.3025770869123972,2.1279042192938276,-0.33242471265450957,-0.39240070950050854,0.5512660173470204,-1.9338917553280288,-0.5745330198140897,-0.39240070950050854
| 3,375
|
Calcium ion binding
| 16
| 81
| 2.564146
| 0.010343
|
O14967,Q02818,P07384,P43304,Q9Y4G8,Q14257,Q03001,Q02487,Q9NWM8,Q6KCM7,Q9BRK5,P80303,P42566,O43852,Q96AY3,P41208
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
281,324,68,200,108,16,17,80,83,311,213,22,265,85,124,216
|
2526,281,1167,1626,85,1763,1693,2533,2029,2825,2580,68,1964,1898,1495,3115,950,1633,2183,2987,1036,1037,3201,495,1841,861,665,1272,1908,1330,1910,3219,216,265,200,1128,916,2202,2635,2722,637,3132,22,80,324,17,1049,1797,2801,2642,16,2965,335,1137,311,2600,2068,924,1007,502,645,3349,2346,124,817,3228,1204,465,213,1298,2607,1949,83,2778,891,791,2520,1750,892,487,108
|
-0.45274711809482365,1.0831656426328216,0.19054865591249434,-0.038231613171792155,2.1039880520769403,-0.09631286647900751,-0.0672262509964336,-0.45274711809482365,-0.21360297580762733,-0.6668117578076647,-0.4830577925150717,2.294161378716793,-0.18413660636999382,-0.15476681385717422,0.019486354875994212,-1.04369050099163,0.33082515613705404,-0.038231613171792155,-0.2728238448155597,-0.82235748271142,0.27495414250230754,0.27495414250230754,-1.334155331699041,0.7403936172598823,-0.1254926486793712,0.38638510613707605,0.5512660173470204,0.13386805297961285,-0.15476681385717422,0.10540172980990664,-0.15476681385717422,-1.3995762482720377,1.2635525405656844,1.1091068208502726,1.340025485497747,0.21876491453847344,0.358643578170959,-0.2728238448155597,-0.5134593662434148,-0.5745330198140897,0.5784922208777676,-1.075641485634037,3.429711270359728,2.1756112509536085,1.004988400356168,3.7334856981138764,0.27495414250230754,-0.09631286647900751,-0.6359637761900813,-0.5134593662434148,3.7764352379093236,-0.7910758719515134,0.978809595175081,0.21876491453847344,1.031106974534266,-0.4830577925150717,-0.21360297580762733,0.358643578170959,0.30292897251860446,0.7403936172598823,0.5784922208777676,-2.9486886703672535,-0.33242471265450957,1.8136162149972994,0.44164086630862914,-1.4324034421386347,0.19054865591249434,0.7938228645047847,1.2890979463364292,0.13386805297961285,-0.4830577925150717,-0.15476681385717422,2.1279042192938276,-0.6052040240979027,0.38638510613707605,0.4691567512932392,-0.42252790140681873,-0.0672262509964336,0.38638510613707605,0.7671410746721091,1.9595949228824863
| 3,375
|
Transferase
| 78
| 383
| 2.56396
| 0.010349
|
Q13546,Q16836,P43490,Q4G0N4,P37268,P49841,Q7Z2T5,P23786,Q6UWE0,Q08J23,O95155,Q13126,Q96EY8,Q99707,Q9UNQ2,Q15418,Q96G23,P28161,O43813,P51003,Q9BWD1,Q15120,Q8NI60,Q12933,Q13464,Q9C0D9,Q9NRA0,Q9BRR6,Q9H488,P49366,Q16739,Q9HCL2,Q9UKG9,P31751,Q13395,Q68CQ7,O94822,P13807,Q8NCH0,O14976,P55263,Q9UII4,Q9HA64,Q9BQC3,P51812,Q04446,Q8NFF5,P50416,Q16512,Q2TAA5,Q5TAX3,Q16762,Q8TD30,Q9Y3D8,O14757,O15228,Q9NT62,Q13555,O00411,Q9BT22,Q96EP0,Q8IXJ6,P24941,Q8IU81,Q86YH6,P49427,O95071,O14936,P35610,Q99640,O75600,Q9NRG0,O43252,P46977,P46934,O43683,O15269,O14929
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
528,15,14,23,521,32,543,34,542,41,42,43,48,570,52,53,54,557,554,559,88,90,93,96,104,106,109,118,121,130,133,158,160,154,163,170,166,167,185,191,193,224,236,244,239,261,272,266,307,309,310,308,326,329,330,338,361,355,354,376,374,372,367,371,370,388,387,383,407,444,448,482,469,474,473,470,490,488
|
1068,722,354,795,1429,579,2575,2238,330,1257,1430,488,383,191,987,796,338,490,1113,1372,899,3059,1433,2295,2357,469,2984,2527,470,1168,554,1378,859,751,3162,2920,2577,1170,2625,448,630,166,1261,387,42,2360,2856,2950,1893,724,2670,2923,1895,2857,1839,2485,2244,1961,1962,1897,801,2712,1493,1698,1324,1560,1561,1325,1771,2301,903,2114,2828,2363,802,1631,633,1441,904,3041,167,1840,1773,2788,1902,1634,2364,1077,1217,1386,906,1498,1445,2789,1078,2831,2035,1079,2118,2186,34,1176,2368,367,1703,1566,664,2189,1777,557,1970,2309,1908,2751,2861,2540,1125,954,154,2039,1178,2955,1331,1568,407,3116,1500,2427,521,2677,2122,1911,756,1705,1846,1571,14,2793,473,757,474,2200,995,1041,3320,914,130,388,2123,1130,805,32,2254,266,3250,559,2048,239,3342,917,958,1976,669,1575,2318,1576,2758,193,867,2376,2925,2959,2683,2548,1454,1647,1648,3015,1280,1047,2866,2055,872,2837,261,1583,2550,1186,1087,834,41,2962,1513,1514,96,2899,2442,43,673,873,2764,2900,3134,163,807,104,2927,528,355,585,810,1656,1657,1588,2446,1658,3104,90,2690,2139,1347,53,2448,307,1859,1348,133,308,1290,15,3148,309,3167,23,768,2392,2064,2065,310,2970,1722,1464,170,2394,542,2875,1465,1232,2454,1726,562,1664,1727,543,1728,1729,3029,640,1294,879,2932,2396,1234,2217,964,2562,370,371,372,2971,1996,3197,2844,882,3279,185,645,272,3287,93,2398,1869,967,326,1934,2344,1999,1935,1353,1402,2001,2847,1202,374,48,3178,54,2272,1817,1013,2734,1151,1605,1476,2813,1940,444,570,2699,1205,1942,2514,244,118,376,1409,1609,1103,3357,742,88,2403,2656,3073,1357,106,1675,1947,2657,1153,121,2351,1741,2089,846,1743,1061,236,3353,158,2092,1681,1207,2979,109,482,785,361,2938,1541,1023,787,2407,2408,939,747,1620,2012,981,689,1881,224,691,160,1024,2164,3302,983,2234,3241,52,2013,720,1829,2291,329,1955,2917,942,2851,2620,2852,3078
|
0.24689976348114367,0.49659904864423754,0.9262690243148245,0.44164086630862914,0.048211934796472365,0.6327337919013768,-0.4830577925150717,-0.3025770869123972,0.978809595175081,0.13386805297961285,0.048211934796472365,0.7403936172598823,0.873480632258922,1.3654085471612543,0.30292897251860446,0.44164086630862914,0.952569994453112,0.7403936172598823,0.21876491453847344,0.07685003800728503,0.358643578170959,-0.948331973940958,0.048211934796472365,-0.33242471265450957,-0.36236611826561227,0.7671410746721091,-0.82235748271142,-0.45274711809482365,0.7671410746721091,0.19054865591249434,0.6597506092154378,0.07685003800728503,0.38638510613707605,0.4691567512932392,-1.1719828815512887,-0.7598800080904538,-0.4830577925150717,0.19054865591249434,-0.5134593662434148,0.7938228645047847,0.5784922208777676,1.491534732272122,0.13386805297961285,0.873480632258922,2.7129169777181765,-0.36236611826561227,-0.6977474581428348,-0.7910758719515134,-0.15476681385717422,0.49659904864423754,-0.5439512892731678,-0.7598800080904538,-0.15476681385717422,-0.6977474581428348,-0.1254926486793712,-0.42252790140681873,-0.3025770869123972,-0.18413660636999382,-0.18413660636999382,-0.15476681385717422,0.44164086630862914,-0.5745330198140897,0.019486354875994212,-0.0672262509964336,0.10540172980990664,-0.009327790283860563,-0.009327790283860563,0.10540172980990664,-0.09631286647900751,-0.33242471265450957,0.358643578170959,-0.24316559991811548,-0.6668117578076647,-0.36236611826561227,0.44164086630862914,-0.038231613171792155,0.5784922208777676,0.048211934796472365,0.358643578170959,-0.9167120699523604,1.491534732272122,-0.1254926486793712,-0.09631286647900751,-0.6359637761900813,-0.15476681385717422,-0.038231613171792155,-0.36236611826561227,0.24689976348114367,0.16225002844017103,0.07685003800728503,0.358643578170959,0.019486354875994212,0.048211934796472365,-0.6359637761900813,0.24689976348114367,-0.6668117578076647,-0.21360297580762733,0.24689976348114367,-0.24316559991811548,-0.2728238448155597,2.985614892363513,0.19054865591249434,-0.36236611826561227,0.8999061013249092,-0.0672262509964336,-0.009327790283860563,0.5512660173470204,-0.2728238448155597,-0.09631286647900751,0.6597506092154378,-0.18413660636999382,-0.33242471265450957,-0.15476681385717422,-0.6052040240979027,-0.6977474581428348,-0.45274711809482365,0.21876491453847344,0.33082515613705404,1.5665946676492313,-0.21360297580762733,0.19054865591249434,-0.7910758719515134,0.10540172980990664,-0.009327790283860563,0.8469920138668321,-1.04369050099163,0.019486354875994212,-0.39240070950050854,0.713579835070738,-0.5439512892731678,-0.24316559991811548,-0.15476681385717422,0.4691567512932392,-0.0672262509964336,-0.1254926486793712,-0.009327790283860563,3.797869337859779,-0.6359637761900813,0.7671410746721091,0.4691567512932392,0.7671410746721091,-0.2728238448155597,0.30292897251860446,0.27495414250230754,-2.1390993722008798,0.358643578170959,1.7645918959276166,0.873480632258922,-0.24316559991811548,0.21876491453847344,0.44164086630862914,3.030593559630485,-0.3025770869123972,1.1091068208502726,-1.5976919926421527,0.6597506092154378,-0.21360297580762733,1.1865840591524877,-2.6630754640461913,0.358643578170959,0.33082515613705404,-0.18413660636999382,0.5512660173470204,-0.009327790283860563,-0.33242471265450957,-0.009327790283860563,-0.6052040240979027,1.3654085471612543,0.38638510613707605,-0.36236611826561227,-0.7598800080904538,-0.7910758719515134,-0.5439512892731678,-0.45274711809482365,0.048211934796472365,-0.038231613171792155,-0.038231613171792155,-0.8537243644783261,0.13386805297961285,0.27495414250230754,-0.6977474581428348,-0.21360297580762733,0.38638510613707605,-0.6668117578076647,1.1349899370587961,-0.009327790283860563,-0.45274711809482365,0.19054865591249434,0.24689976348114367,0.41405059073486755,2.7358317422764893,-0.7910758719515134,0.019486354875994212,0.019486354875994212,2.031985358818018,-0.7287703736920425,-0.39240070950050854,2.689966750135784,0.5512660173470204,0.38638510613707605,-0.6052040240979027,-0.7287703736920425,-1.075641485634037,1.516605184692839,0.44164086630862914,1.9595949228824863,-0.7598800080904538,0.713579835070738,0.9262690243148245,0.6327337919013768,0.44164086630862914,-0.038231613171792155,-0.038231613171792155,-0.009327790283860563,-0.39240070950050854,-0.038231613171792155,-1.0118216311731156,2.0800297213070706,-0.5439512892731678,-0.24316559991811548,0.10540172980990664,2.4817813149505383,-0.39240070950050854,1.031106974534266,-0.1254926486793712,0.10540172980990664,1.7400097763933111,1.031106974534266,0.13386805297961285,3.797869337859779,-1.1076741576662066,1.031106974534266,-1.1719828815512887,3.4077973078556516,0.4691567512932392,-0.36236611826561227,-0.21360297580762733,-0.21360297580762733,1.031106974534266,-0.7910758719515134,-0.0672262509964336,0.048211934796472365,1.491534732272122,-0.36236611826561227,0.6866990592950521,-0.6977474581428348,0.048211934796472365,0.16225002844017103,-0.39240070950050854,-0.0672262509964336,0.6597506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| 3,375
|
Second messenger mediated signaling
| 10
| 28
| 2.55932
| 0.010488
|
P00813,P49841,O75844,O00330,Q9Y4G8,P49427,P42858,Q8NE86,Q13131,P28161
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,32,471,697,108,388,175,775,673,557
|
697,471,0,2628,1495,1037,1634,2364,1841,2188,557,1567,1846,175,388,32,2317,1507,1647,2380,1049,673,2647,775,2889,978,791,108
|
0.5239685462529114,0.7671410746721091,8.05927987366474,-0.5134593662434148,0.019486354875994212,0.27495414250230754,-0.038231613171792155,-0.36236611826561227,-0.1254926486793712,-0.2728238448155597,0.6597506092154378,-0.009327790283860563,-0.1254926486793712,1.4664132535336514,0.873480632258922,3.030593559630485,-0.33242471265450957,0.019486354875994212,-0.038231613171792155,-0.36236611826561227,0.27495414250230754,0.5512660173470204,-0.5134593662434148,0.4691567512932392,-0.6977474581428348,0.33082515613705404,0.4691567512932392,1.9595949228824863
| 3,375
|
Intracellular protein transmembrane transport
| 6
| 25
| 2.556756
| 0.010565
|
Q99595,O60830,Q15388,Q15629,Q3ZCQ8,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,4,37,211,437,154
|
1216,1886,2666,4,3097,1891,449,1696,2181,1631,154,606,2129,2203,2257,37,211,437,2068,1814,1098,2083,64,1308,688
|
0.16225002844017103,-0.15476681385717422,-0.5439512892731678,5.415645674566234,-1.0118216311731156,-0.15476681385717422,0.7938228645047847,-0.0672262509964336,-0.2728238448155597,-0.038231613171792155,1.5665946676492313,0.6056479018936,-0.24316559991811548,-0.2728238448155597,-0.3025770869123972,2.84988124164933,1.2890979463364292,0.8204396326290617,-0.21360297580762733,-0.09631286647900751,0.24689976348114367,-0.21360297580762733,2.3648106652398435,0.13386805297961285,0.5512660173470204
| 3,375
|
Lipid homeostasis
| 13
| 28
| 2.555058
| 0.010617
|
Q96CP7,Q9Y5P4,P35610,O15118,P09455,Q9BWH2,Q86YV9,Q9NQC3,Q6YHU6,Q8WTV0,O15260,Q13131,Q9HCL2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,694,407,627,319,359,460,230,413,50,19,673,158
|
1428,627,1371,19,2535,319,1902,1970,407,3238,1716,673,737,2805,1807,413,460,50,257,1202,359,1949,158,230,1747,2705,694,1548
|
0.048211934796472365,0.5784922208777676,0.07685003800728503,3.6688559426474816,-0.45274711809482365,1.004988400356168,-0.15476681385717422,-0.18413660636999382,0.8469920138668321,-1.5313475075418816,-0.0672262509964336,0.5512660173470204,0.49659904864423754,-0.6359637761900813,-0.09631286647900751,0.8469920138668321,0.7938228645047847,2.5978067214134675,1.1608155122181425,0.19054865591249434,0.9262690243148245,-0.15476681385717422,1.5665946676492313,1.2379520800421246,-0.0672262509964336,-0.5439512892731678,0.5512660173470204,0.019486354875994212
| 3,375
|
Monosaccharide biosynthetic process
| 6
| 26
| 2.547941
| 0.010836
|
P11310,Q9UBX3,P53007,Q92520,Q93009,Q9BYT8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,400,227,172,443,57
|
1367,1372,1693,2244,1699,1,1120,2115,3009,2830,2493,1130,1642,227,2796,997,432,2899,1135,1051,172,443,1202,57,400,1750
|
0.07685003800728503,0.07685003800728503,-0.0672262509964336,-0.3025770869123972,-0.0672262509964336,7.367385577094042,0.21876491453847344,-0.24316559991811548,-0.8537243644783261,-0.6668117578076647,-0.42252790140681873,0.21876491453847344,-0.038231613171792155,1.2379520800421246,-0.6359637761900813,0.30292897251860446,0.8204396326290617,-0.7287703736920425,0.21876491453847344,0.27495414250230754,1.491534732272122,0.8204396326290617,0.19054865591249434,2.4584637978137454,0.873480632258922,-0.0672262509964336
| 3,375
|
Abnormal circulating metabolite concentration
| 93
| 360
| 2.544357
| 0.010948
|
P11310,P78330,P48735,Q15392,Q16836,O00170,Q4G0N4,P37268,P03886,O43772,P23786,O00192,Q08J23,Q96EY8,Q99707,Q96RL7,P28070,Q9H267,Q9BUK6,Q9NWM8,O75306,Q96CU9,Q9BWD1,Q15120,Q96BR5,P14174,P22626,Q9H9E3,P05166,P50402,P50542,O14979,P53992,O75880,O96007,Q7Z2Z2,Q969X5,O75648,Q9HC07,P12235,Q9UKG1,Q92890,Q9UGP8,P31751,Q9UHD2,O75190,P16930,P42858,P36776,O43676,Q07021,O75879,Q70HW3,Q9Y223,Q9UDY2,Q9NPL8,P46020,P55263,O00330,Q12769,Q96RR1,Q15800,Q15056,Q9Y487,Q8N511,Q13423,P00846,Q8NFF5,Q6PML9,P50416,Q5JRX3,P09001,P41440,Q9Y5L0,Q9BT22,Q86YH6,Q4J6C6,O43819,O14936,Q96MW5,Q9HCC0,Q96BN8,P35610,O75312,Q92766,Q00796,Q15813,Q9BPX6,O95831,P00390,Q6P4I2,P51649,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,526,11,12,15,512,23,521,31,33,34,537,41,48,570,51,556,592,79,83,581,86,88,90,619,101,603,107,602,605,606,110,608,129,631,639,135,630,139,143,152,150,688,154,689,659,663,175,667,177,671,181,188,720,199,718,192,193,697,704,219,234,233,250,256,262,260,272,270,266,296,304,321,382,376,370,393,385,383,418,420,417,407,404,442,432,435,465,449,450,457,475,471
|
1686,944,512,537,697,795,898,2104,1257,3242,383,110,3059,1028,2527,177,1626,33,385,2666,1377,3161,2920,659,1321,1690,581,404,1763,2297,2241,630,471,181,129,800,1766,1894,449,1173,1695,631,1896,1262,450,2857,1839,2485,2244,260,3079,31,1697,1897,1322,2179,2713,2113,602,2827,3269,1324,2487,1770,2924,2748,1561,1325,3142,1265,304,992,2536,1326,902,1495,1383,2031,2302,1900,2032,1772,2363,1,1120,2115,143,2630,101,2987,3025,663,2582,1217,2953,827,2246,1329,1635,1078,1842,1776,603,2539,909,828,2187,34,2368,2037,1777,556,1218,2584,1970,1908,953,1219,830,154,3255,2194,1179,2676,2835,1568,407,2041,3256,1569,2542,1181,667,2493,2427,521,2677,2678,3371,1448,1081,1502,2719,2122,864,321,1221,1039,175,1707,956,911,192,2371,1335,11,730,2374,2756,2956,605,266,606,1222,1572,2048,3282,2431,475,1975,1183,2957,1709,1225,3011,1916,608,1575,1643,1786,2758,193,2682,2050,868,2376,2203,1712,2257,3238,2865,526,2637,1132,3270,432,2592,2898,2439,2205,2500,1979,1087,671,41,2962,703,704,2326,2899,835,262,1654,1853,2264,1283,2642,1090,3352,1134,1459,1191,2446,233,90,1517,12,2872,1593,1987,234,435,876,1003,1519,1803,15,2727,3167,23,3347,393,296,3157,3275,2452,1808,457,1809,270,1232,188,1726,2455,639,2395,1992,2340,2729,1867,1525,2933,370,2563,1602,256,2845,3259,272,2343,1350,3177,1145,1870,1055,2147,442,150,2076,1096,135,816,417,619,86,1098,2149,48,2513,418,51,2082,219,570,2974,1356,3138,465,1408,376,1102,1058,2226,2700,79,1536,88,1060,2280,592,1412,2351,819,107,2090,139,420,937,2092,718,2978,1681,1361,746,3324,83,821,2093,2095,2096,3006,1161,2915,2356,2469,1106,199,688,689,1881,1750,2470,152,2097,720,2235,2098,2982,2411,250,1253,2917,1254,382,2851,2102,2620,1423,3078,943
|
-0.0672262509964336,0.33082515613705404,0.713579835070738,0.6866990592950521,0.5239685462529114,0.44164086630862914,0.358643578170959,-0.24316559991811548,0.13386805297961285,-1.5644818109642689,0.873480632258922,1.9111150023933372,-0.948331973940958,0.27495414250230754,-0.45274711809482365,1.441240326714265,-0.038231613171792155,3.0081206146023467,0.873480632258922,-0.5439512892731678,0.07685003800728503,-1.1719828815512887,-0.7598800080904538,0.5512660173470204,0.10540172980990664,-0.0672262509964336,0.6327337919013768,0.8469920138668321,-0.09631286647900751,-0.33242471265450957,-0.3025770869123972,0.5784922208777676,0.7671410746721091,1.416015523904057,1.7645918959276166,0.44164086630862914,-0.09631286647900751,-0.15476681385717422,0.7938228645047847,0.19054865591249434,-0.0672262509964336,0.5784922208777676,-0.15476681385717422,0.13386805297961285,0.7938228645047847,-0.6977474581428348,-0.1254926486793712,-0.42252790140681873,-0.3025770869123972,1.1349899370587961,-0.980035309228183,3.030593559630485,-0.0672262509964336,-0.15476681385717422,0.10540172980990664,-0.2728238448155597,-0.5745330198140897,-0.24316559991811548,0.6056479018936,-0.6668117578076647,-1.7312845351077755,0.10540172980990664,-0.42252790140681873,-0.09631286647900751,-0.7598800080904538,-0.6052040240979027,-0.009327790283860563,0.10540172980990664,-1.1076741576662066,0.13386805297961285,1.031106974534266,0.30292897251860446,-0.45274711809482365,0.10540172980990664,0.358643578170959,0.019486354875994212,0.07685003800728503,-0.21360297580762733,-0.33242471265450957,-0.15476681385717422,-0.21360297580762733,-0.09631286647900751,-0.36236611826561227,7.367385577094042,0.21876491453847344,-0.24316559991811548,1.6412063989989234,-0.5134593662434148,1.983768672818817,-0.82235748271142,-0.8851760478860837,0.5512660173470204,-0.4830577925150717,0.16225002844017103,-0.7910758719515134,0.41405059073486755,-0.3025770869123972,0.10540172980990664,-0.038231613171792155,0.24689976348114367,-0.1254926486793712,-0.09631286647900751,0.6056479018936,-0.45274711809482365,0.358643578170959,0.41405059073486755,-0.2728238448155597,2.985614892363513,-0.36236611826561227,-0.21360297580762733,-0.09631286647900751,0.6597506092154378,0.16225002844017103,-0.4830577925150717,-0.18413660636999382,-0.15476681385717422,0.33082515613705404,0.16225002844017103,0.41405059073486755,1.5665946676492313,-1.6643385894420446,-0.2728238448155597,0.19054865591249434,-0.5439512892731678,-0.6668117578076647,-0.009327790283860563,0.8469920138668321,-0.21360297580762733,-1.6643385894420446,-0.009327790283860563,-0.45274711809482365,0.19054865591249434,0.5512660173470204,-0.42252790140681873,-0.39240070950050854,0.713579835070738,-0.5439512892731678,-0.5439512892731678,-7.168005489173489,0.048211934796472365,0.24689976348114367,0.019486354875994212,-0.5745330198140897,-0.24316559991811548,0.38638510613707605,1.004988400356168,0.16225002844017103,0.27495414250230754,1.4664132535336514,-0.0672262509964336,0.33082515613705404,0.358643578170959,1.3654085471612543,-0.36236611826561227,0.10540172980990664,4.470238014994655,0.49659904864423754,-0.36236611826561227,-0.6052040240979027,-0.7910758719515134,0.6056479018936,1.1091068208502726,0.6056479018936,0.16225002844017103,-0.009327790283860563,-0.21360297580762733,-1.8322588413061764,-0.39240070950050854,0.7671410746721091,-0.18413660636999382,0.19054865591249434,-0.7910758719515134,-0.0672262509964336,0.16225002844017103,-0.8537243644783261,-0.15476681385717422,0.6056479018936,-0.009327790283860563,-0.038231613171792155,-0.09631286647900751,-0.6052040240979027,1.3654085471612543,-0.5439512892731678,-0.21360297580762733,0.38638510613707605,-0.36236611826561227,-0.2728238448155597,-0.0672262509964336,-0.3025770869123972,-1.5313475075418816,-0.6977474581428348,0.713579835070738,-0.5134593662434148,0.21876491453847344,-1.7312845351077755,0.8204396326290617,-0.4830577925150717,-0.7287703736920425,-0.39240070950050854,-0.2728238448155597,-0.42252790140681873,-0.18413660636999382,0.24689976348114367,0.5512660173470204,2.7358317422764893,-0.7910758719515134,0.5239685462529114,0.5239685462529114,-0.33242471265450957,-0.7287703736920425,0.41405059073486755,1.1349899370587961,-0.038231613171792155,-0.1254926486793712,-0.3025770869123972,0.13386805297961285,-0.5134593662434148,0.24689976348114367,-3.129297060587511,0.21876491453847344,0.048211934796472365,0.19054865591249434,-0.39240070950050854,1.212296082730813,2.0800297213070706,0.019486354875994212,4.031896411144352,-0.6977474581428348,-0.009327790283860563,-0.18413660636999382,1.212296082730813,0.8204396326290617,0.38638510613707605,0.30292897251860446,0.019486354875994212,-0.09631286647900751,3.797869337859779,-0.5745330198140897,-1.1719828815512887,3.4077973078556516,-2.7696897938215086,0.873480632258922,1.057165873125376,-1.1397880951540584,-1.7648689174206336,-0.39240070950050854,-0.09631286647900751,0.7938228645047847,-0.09631286647900751,1.1091068208502726,0.16225002844017103,1.39073841091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| 3,375
|
Metabolism of steroids
| 10
| 43
| 2.528865
| 0.011443
|
Q9H2C2,Q15800,Q99538,Q15392,P38435,Q16850,Q9BWD1,Q9HCL2,O14734,P30536
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
66,234,137,12,174,82,88,158,237,341
|
1687,2237,237,2535,2299,2923,661,1962,1840,2830,908,2118,2489,341,521,174,3100,1041,1975,2495,608,2321,2866,1716,1719,356,1459,1925,2690,12,1230,1987,234,82,2599,964,2071,2347,137,88,66,158,2356
|
-0.0672262509964336,-0.3025770869123972,1.1865840591524877,-0.45274711809482365,-0.33242471265450957,-0.7598800080904538,0.5512660173470204,-0.18413660636999382,-0.1254926486793712,-0.6668117578076647,0.358643578170959,-0.24316559991811548,-0.42252790140681873,0.952569994453112,0.713579835070738,1.4664132535336514,-1.0118216311731156,0.27495414250230754,-0.18413660636999382,-0.42252790140681873,0.6056479018936,-0.33242471265450957,-0.6977474581428348,-0.0672262509964336,-0.0672262509964336,0.9262690243148245,0.048211934796472365,-0.15476681385717422,-0.5439512892731678,4.031896411144352,0.16225002844017103,-0.18413660636999382,1.212296082730813,2.1279042192938276,-0.4830577925150717,0.33082515613705404,-0.21360297580762733,-0.33242471265450957,1.6907038084850876,2.1039880520769403,2.341300334418682,1.5665946676492313,-0.33242471265450957
| 3,375
|
calmodulin-related
| 8
| 14
| 2.524779
| 0.011577
|
Q02818,Q9BPX6,Q15293,Q14257,Q9BRK5,P80303,O43852,P41208
|
Functions
|
Panther Protein class
|
panther_protein_class
|
324,465,335,16,213,22,85,216
|
85,1495,1330,1910,216,2722,22,324,16,335,502,3228,465,213
|
2.1039880520769403,0.019486354875994212,0.10540172980990664,-0.15476681385717422,1.2635525405656844,-0.5745330198140897,3.429711270359728,1.004988400356168,3.7764352379093236,0.978809595175081,0.7403936172598823,-1.4324034421386347,0.7938228645047847,1.2890979463364292
| 3,375
|
Regulation of response to external stimulus
| 42
| 139
| 2.524562
| 0.011584
|
P00813,Q12846,Q13546,P12956,Q99538,O43657,O14936,Q99497,Q96PK6,P80303,Q9UKG1,Q92890,Q9NUD5,Q9BXW9,Q9Y4E8,Q9UHD2,Q96BN8,Q9Y3Z3,Q6UWE0,Q14671,Q16512,P27797,Q00013,Q96G23,P28070,Q9BUI4,Q9UIV1,Q7Z434,P04439,Q8ND56,Q9UMX5,Q8NHP6,Q9UII4,P60900,P14174,O75844,Q9NZ08,O15360,Q96EP0,Q7Z739,Q8IXJ6,Q86UT6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,527,528,8,137,384,383,20,681,22,152,150,685,419,425,689,417,692,542,295,307,665,670,54,556,189,190,196,318,462,89,613,224,344,101,471,103,115,374,501,372,241
|
897,383,796,115,2984,384,1374,2482,1116,2578,1889,3039,471,2533,1891,1261,900,2670,0,1962,2825,318,2713,2486,2030,2180,1628,1631,3327,8,1267,101,1634,1701,1841,907,2247,952,2424,2038,2189,665,556,2309,2492,2540,1781,3174,1334,956,1127,2316,831,1849,2128,1275,759,344,2959,869,1648,22,670,872,2550,2056,671,1229,2996,527,873,2764,2640,528,2641,3344,1854,295,2446,1927,1518,2967,2266,307,1348,2211,3167,2335,542,196,1396,501,2396,241,372,3188,1053,462,775,613,2694,2567,2075,150,417,374,54,1817,1013,681,1606,2463,20,137,2699,1015,189,935,3235,419,2351,848,685,3057,3324,3094,103,2409,3299,689,224,190,152,89,2981,692,425,895,3292
|
0.358643578170959,0.873480632258922,0.44164086630862914,1.862456329832627,-0.82235748271142,0.873480632258922,0.07685003800728503,-0.42252790140681873,0.21876491453847344,-0.4830577925150717,-0.15476681385717422,-0.9167120699523604,0.7671410746721091,-0.45274711809482365,-0.15476681385717422,0.13386805297961285,0.358643578170959,-0.5439512892731678,8.05927987366474,-0.18413660636999382,-0.6668117578076647,1.004988400356168,-0.5745330198140897,-0.42252790140681873,-0.21360297580762733,-0.2728238448155597,-0.038231613171792155,-0.038231613171792155,-2.242657726526616,4.85801582075318,0.13386805297961285,1.983768672818817,-0.038231613171792155,-0.0672262509964336,-0.1254926486793712,0.358643578170959,-0.3025770869123972,0.33082515613705404,-0.39240070950050854,-0.21360297580762733,-0.2728238448155597,0.5512660173470204,0.6597506092154378,-0.33242471265450957,-0.42252790140681873,-0.45274711809482365,-0.09631286647900751,-1.2042581055902233,0.10540172980990664,0.33082515613705404,0.21876491453847344,-0.33242471265450957,0.41405059073486755,-0.1254926486793712,-0.24316559991811548,0.13386805297961285,0.4691567512932392,0.952569994453112,-0.7910758719515134,0.38638510613707605,-0.038231613171792155,3.429711270359728,0.5512660173470204,0.38638510613707605,-0.45274711809482365,-0.21360297580762733,0.5512660173470204,0.16225002844017103,-0.82235748271142,0.713579835070738,0.38638510613707605,-0.6052040240979027,-0.5134593662434148,0.713579835070738,-0.5134593662434148,-2.734085777276208,-0.1254926486793712,1.057165873125376,-0.39240070950050854,-0.15476681385717422,0.019486354875994212,-0.7910758719515134,-0.3025770869123972,1.031106974534266,0.10540172980990664,-0.2728238448155597,-1.1719828815512887,-0.33242471265450957,0.6866990592950521,1.3654085471612543,0.07685003800728503,0.7403936172598823,-0.36236611826561227,1.1865840591524877,0.8999061013249092,-1.2366133611756898,0.27495414250230754,0.7938228645047847,0.4691567512932392,0.6056479018936,-0.5439512892731678,-0.45274711809482365,-0.21360297580762733,1.6163849582577512,0.8469920138668321,0.8999061013249092,2.4817813149505383,-0.09631286647900751,0.30292897251860446,0.5512660173470204,-0.009327790283860563,-0.39240070950050854,3.582293433383776,1.6907038084850876,-0.5439512892731678,0.30292897251860446,1.39073841091754,0.358643578170959,-1.4982894378117122,0.8469920138668321,-0.33242471265450957,0.41405059073486755,0.5512660173470204,-0.9167120699523604,-2.1390993722008798,-0.980035309228183,1.983768672818817,-0.36236611826561227,-1.899941473864839,0.5512660173470204,1.2635525405656844,1.39073841091754,1.6163849582577512,2.1039880520769403,-0.7910758719515134,0.5512660173470204,0.8469920138668321,0.38638510613707605,-1.8660637299899208
| 3,375
|
Import into cell
| 6
| 27
| 2.510557
| 0.012054
|
Q8TDW0,Q99497,P20337,P30825,P08195,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
312,20,119,26,252,154
|
1436,2027,2243,2179,2628,1263,1963,252,1900,119,26,154,955,321,1710,2128,2132,2903,1595,2267,542,312,20,2814,2280,2351,2619
|
0.048211934796472365,-0.21360297580762733,-0.3025770869123972,-0.2728238448155597,-0.5134593662434148,0.13386805297961285,-0.18413660636999382,1.1608155122181425,-0.15476681385717422,1.8380591236082113,3.164753514554234,1.5665946676492313,0.33082515613705404,1.004988400356168,-0.0672262509964336,-0.24316559991811548,-0.24316559991811548,-0.7287703736920425,-0.009327790283860563,-0.3025770869123972,0.6866990592950521,1.031106974534266,3.582293433383776,-0.6359637761900813,-0.3025770869123972,-0.33242471265450957,-0.4830577925150717
| 3,375
|
Calmodulin
| 8
| 17
| 2.5038
| 0.012287
|
Q02818,Q9BPX6,Q15293,Q14257,Q9BRK5,P80303,O43852,P41208
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
324,465,335,16,213,22,85,216
|
85,1495,1910,216,2635,2722,22,324,16,335,1724,2603,502,1813,3228,465,213
|
2.1039880520769403,0.019486354875994212,-0.15476681385717422,1.2635525405656844,-0.5134593662434148,-0.5745330198140897,3.429711270359728,1.004988400356168,3.7764352379093236,0.978809595175081,-0.0672262509964336,-0.4830577925150717,0.7403936172598823,-0.09631286647900751,-1.4324034421386347,0.7938228645047847,1.2890979463364292
| 3,375
|
Intracellular calcium-sensing protein
| 8
| 17
| 2.5038
| 0.012287
|
Q02818,Q9BPX6,Q15293,Q14257,Q9BRK5,P80303,O43852,P41208
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
324,465,335,16,213,22,85,216
|
85,1495,1910,216,2635,2722,22,324,16,335,1724,2603,502,1813,3228,465,213
|
2.1039880520769403,0.019486354875994212,-0.15476681385717422,1.2635525405656844,-0.5134593662434148,-0.5745330198140897,3.429711270359728,1.004988400356168,3.7764352379093236,0.978809595175081,-0.0672262509964336,-0.4830577925150717,0.7403936172598823,-0.09631286647900751,-1.4324034421386347,0.7938228645047847,1.2890979463364292
| 3,375
|
Ketosis
| 6
| 19
| 2.499241
| 0.012446
|
P11310,Q96RR1,P12235,Q96EY8,Q9HCC0,P09001
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,219,143,48,420,304
|
1324,1265,304,2363,1,143,1635,1842,2368,1446,407,1916,1575,2446,3347,2076,48,219,420
|
0.10540172980990664,0.13386805297961285,1.031106974534266,-0.36236611826561227,7.367385577094042,1.6412063989989234,-0.038231613171792155,-0.1254926486793712,-0.36236611826561227,0.048211934796472365,0.8469920138668321,-0.15476681385717422,-0.009327790283860563,-0.39240070950050854,-2.7696897938215086,-0.21360297580762733,2.6439590132330637,1.2635525405656844,0.8469920138668321
| 3,375
|
Regulation of cellular carbohydrate metabolic process
| 9
| 29
| 2.499234
| 0.012446
|
Q9UNI6,P11310,P49841,Q92520,Q93009,Q9BYT8,Q15120,P31751,Q9Y6N1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
402,1,32,172,443,57,90,154,427
|
1367,1687,1372,2531,1693,471,1322,1,2715,154,3211,1130,805,32,997,2836,2377,2899,3195,3104,90,1135,172,443,1202,57,2007,402,427
|
0.07685003800728503,-0.0672262509964336,0.07685003800728503,-0.45274711809482365,-0.0672262509964336,0.7671410746721091,0.10540172980990664,7.367385577094042,-0.5745330198140897,1.5665946676492313,-1.3668267524146023,0.21876491453847344,0.44164086630862914,3.030593559630485,0.30292897251860446,-0.6668117578076647,-0.36236611826561227,-0.7287703736920425,-1.3015623678515262,-1.0118216311731156,2.0800297213070706,0.21876491453847344,1.491534732272122,0.8204396326290617,0.19054865591249434,2.4584637978137454,-0.18413660636999382,0.873480632258922,0.8469920138668321
| 3,375
|
Mitochondria
| 74
| 436
| 2.497874
| 0.012494
|
P11310,Q9UBX3,Q9NQH7,O60830,O75521,Q13423,Q86UV5,Q9BRP1,Q16740,Q9NQE9,P48735,Q16836,P12235,O43819,Q96EX1,Q6P4A7,P50416,Q9HCC0,Q4G0N4,Q9HCL2,Q9NS69,Q9H2D1,Q8WWC4,Q9Y3B8,Q96BN8,O43772,P23786,Q5JRX3,Q15388,O15121,Q6DKK2,Q68CQ7,Q69YU5,Q96EY8,Q6KCM7,Q16762,Q9BYT8,P30837,O75879,Q70HW3,Q9NR28,Q8TD30,Q14168,Q99595,Q7Z434,Q9NZ45,P43304,P21399,P13674,Q13505,P30084,O95140,Q96CU9,Q15120,Q9NVH6,Q9NSE4,Q8NI60,Q3SXM5,Q9Y2R0,Q8WY22,Q9H0B6,O00411,O14949,Q9NYY8,P82933,Q9GZT3,Q9H4I3,Q86UT6,O15091,P53701,Q96AY3,O14734,Q86UY8,Q96QE5
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
1,400,263,4,132,262,396,138,9,140,11,15,143,385,145,269,266,420,23,158,27,29,286,424,417,33,34,296,37,38,165,170,171,48,311,308,57,55,181,188,316,326,325,64,196,67,200,70,76,334,204,331,86,90,91,222,93,218,363,98,360,354,231,379,111,378,247,241,364,253,124,237,122,127
|
3153,697,354,2103,3096,237,1216,231,364,38,3059,3308,1433,3231,1886,2665,33,385,2529,945,2108,3124,1434,4,946,2484,1321,581,2625,2297,947,2241,132,448,2948,630,181,3126,698,1031,1891,2242,331,493,1172,2029,901,449,1696,1262,1438,3237,1897,1322,1174,2113,1073,2748,3142,1265,992,1326,2114,1564,2181,1772,2363,1,2115,143,1122,2986,76,2630,1385,1077,1217,2953,70,1329,1635,1842,1079,2489,2539,634,828,34,1176,1177,2368,1703,2037,1446,664,556,2584,953,2954,2492,1909,204,2674,55,1219,539,1331,2426,2195,1181,667,2427,2678,3010,2719,2122,408,729,1640,1571,200,911,1847,1040,2371,3045,11,3063,2374,3307,2756,2956,1784,266,2720,1572,475,1573,917,3183,1709,253,1575,2318,1576,2758,1086,2681,541,2722,2260,1508,2549,1921,3049,2054,733,111,3133,3270,1509,2799,1649,2960,2638,671,1281,999,1798,1922,1457,3068,3027,262,334,585,325,3234,1392,3184,2557,2207,90,1347,37,2966,1860,9,308,2212,1051,15,3148,2059,218,437,23,3347,3105,768,2062,296,499,2213,921,2969,1462,1661,1231,811,3275,170,1092,171,2393,165,3051,311,2600,1866,2806,3253,269,2840,3226,706,2216,1138,3222,188,2142,1726,963,1727,1468,196,2457,1233,2729,241,396,122,1525,2933,1932,924,2268,3334,502,2563,3245,480,1398,644,2934,563,2509,2069,2070,2846,1527,1295,775,93,1814,646,1667,3177,614,1869,326,3071,1198,286,1238,2460,98,1010,3189,1056,2076,2078,1531,649,124,1936,417,619,1097,1201,86,3031,2909,1202,2650,145,504,1099,48,3178,3136,2883,3107,2513,2274,2884,2735,127,1939,2082,3054,2464,1243,3018,64,3137,1356,1941,465,3246,1408,138,651,3301,933,2700,3109,2466,1301,2815,2605,2403,2227,1739,2404,3272,1819,3289,57,2468,378,3093,360,29,1304,1614,2608,715,247,2352,1876,3319,572,819,1479,2353,1480,2090,1308,1481,3353,420,158,1416,937,718,1680,654,140,263,316,744,27,222,2613,2008,1541,938,786,820,91,746,595,1023,2570,821,1247,787,1209,2162,1210,379,67,3372,2010,2095,2096,3006,686,2915,509,400,1106,3170,3111,3076,2740,1750,3368,2164,3291,3193,857,3360,2290,363,2099,1213,3172,535,793,3141,424,2663,1753,2412,2169,578,1066,3370,2477,2102,1684,1548,943,1067
|
-1.1397880951540584,0.5239685462529114,0.9262690243148245,-0.24316559991811548,-1.0118216311731156,1.1865840591524877,0.16225002844017103,1.212296082730813,0.8999061013249092,2.8043654472386006,-0.948331973940958,-2.0704120237229517,0.048211934796472365,-1.4653079613874214,-0.15476681385717422,-0.5439512892731678,3.0081206146023467,0.873480632258922,-0.45274711809482365,0.33082515613705404,-0.24316559991811548,-1.075641485634037,0.048211934796472365,5.415645674566234,0.33082515613705404,-0.42252790140681873,0.10540172980990664,0.6327337919013768,-0.5134593662434148,-0.33242471265450957,0.33082515613705404,-0.3025770869123972,1.7400097763933111,0.7938228645047847,-0.7910758719515134,0.5784922208777676,1.416015523904057,-1.075641485634037,0.5239685462529114,0.27495414250230754,-0.15476681385717422,-0.3025770869123972,0.978809595175081,0.7403936172598823,0.19054865591249434,-0.21360297580762733,0.358643578170959,0.7938228645047847,-0.0672262509964336,0.13386805297961285,0.048211934796472365,-1.5313475075418816,-0.15476681385717422,0.10540172980990664,0.19054865591249434,-0.24316559991811548,0.24689976348114367,-0.6052040240979027,-1.1076741576662066,0.13386805297961285,0.30292897251860446,0.10540172980990664,-0.24316559991811548,-0.009327790283860563,-0.2728238448155597,-0.09631286647900751,-0.36236611826561227,7.367385577094042,-0.24316559991811548,1.6412063989989234,0.21876491453847344,-0.82235748271142,2.223153155757611,-0.5134593662434148,0.07685003800728503,0.24689976348114367,0.16225002844017103,-0.7910758719515134,2.246862901123615,0.10540172980990664,-0.038231613171792155,-0.1254926486793712,0.24689976348114367,-0.42252790140681873,-0.45274711809482365,0.5784922208777676,0.41405059073486755,2.985614892363513,0.19054865591249434,0.19054865591249434,-0.36236611826561227,-0.0672262509964336,-0.21360297580762733,0.048211934796472365,0.5512660173470204,0.6597506092154378,-0.4830577925150717,0.33082515613705404,-0.7910758719515134,-0.42252790140681873,-0.15476681385717422,1.3145887721057432,-0.5439512892731678,2.4584637978137454,0.16225002844017103,0.6866990592950521,0.10540172980990664,-0.39240070950050854,-0.2728238448155597,0.19054865591249434,0.5512660173470204,-0.39240070950050854,-0.5439512892731678,-0.8537243644783261,-0.5745330198140897,-0.24316559991811548,0.8469920138668321,0.49659904864423754,-0.038231613171792155,-0.009327790283860563,1.340025485497747,0.358643578170959,-0.1254926486793712,0.27495414250230754,-0.36236611826561227,-0.9167120699523604,4.470238014994655,-0.948331973940958,-0.36236611826561227,-2.036174700270587,-0.6052040240979027,-0.7910758719515134,-0.09631286647900751,1.1091068208502726,-0.5745330198140897,-0.009327790283860563,0.7671410746721091,-0.009327790283860563,0.358643578170959,-1.2366133611756898,-0.0672262509964336,1.1608155122181425,-0.009327790283860563,-0.33242471265450957,-0.009327790283860563,-0.6052040240979027,0.24689976348114367,-0.5439512892731678,0.6866990592950521,-0.5745330198140897,-0.3025770869123972,0.019486354875994212,-0.45274711809482365,-0.15476681385717422,-0.9167120699523604,-0.21360297580762733,0.49659904864423754,1.9111150023933372,-1.075641485634037,-1.7312845351077755,0.019486354875994212,-0.6359637761900813,-0.038231613171792155,-0.7910758719515134,-0.5134593662434148,0.5512660173470204,0.13386805297961285,0.30292897251860446,-0.09631286647900751,-0.15476681385717422,0.048211934796472365,-0.948331973940958,-0.8851760478860837,1.1349899370587961,0.978809595175081,0.6327337919013768,1.004988400356168,-1.4982894378117122,0.07685003800728503,-1.2366133611756898,-0.45274711809482365,-0.2728238448155597,2.0800297213070706,0.10540172980990664,2.84988124164933,-0.7910758719515134,-0.1254926486793712,4.511437534011964,1.031106974534266,-0.2728238448155597,0.27495414250230754,3.797869337859779,-1.1076741576662066,-0.21360297580762733,1.2635525405656844,0.8204396326290617,3.4077973078556516,-2.7696897938215086,-1.0118216311731156,0.4691567512932392,-0.21360297580762733,1.057165873125376,0.7403936172598823,-0.2728238448155597,0.358643578170959,-0.7910758719515134,0.048211934796472365,-0.038231613171792155,0.16225002844017103,0.44164086630862914,-1.7648689174206336,1.491534732272122,0.24689976348114367,1.491534732272122,-0.36236611826561227,1.516605184692839,-0.9167120699523604,1.031106974534266,-0.4830577925150717,-0.1254926486793712,-0.6359637761900813,-1.6309777012387325,1.1091068208502726,-0.6668117578076647,-1.4324034421386347,0.5239685462529114,-0.2728238448155597,0.21876491453847344,-1.3995762482720377,1.39073841091754,-0.24316559991811548,-0.0672262509964336,0.33082515613705404,-0.0672262509964336,0.048211934796472365,1.3654085471612543,-0.39240070950050854,0.16225002844017103,-0.5745330198140897,1.1865840591524877,0.873480632258922,1.8136162149972994,0.019486354875994212,-0.7598800080904538,-0.15476681385717422,0.358643578170959,-0.3025770869123972,-2.346841965285264,0.7403936172598823,-0.45274711809482365,-1.5644818109642689,0.7671410746721091,0.07685003800728503,0.5784922208777676,-0.7598800080904538,0.6597506092154378,-0.42252790140681873,-0.21360297580762733,-0.21360297580762733,-0.6668117578076647,0.019486354875994212,0.13386805297961285,0.4691567512932392,2.0560289253619395,-0.09631286647900751,0.5784922208777676,-0.038231613171792155,-1.2042581055902233,0.6056479018936,-0.1254926486793712,1.004988400356168,-0.948331973940958,0.19054865591249434,1.0831656426328216,0.16225002844017103,-0.39240070950050854,2.0078987123817007,0.30292897251860446,-1.2366133611756898,0.27495414250230754,-0.21360297580762733,-0.21360297580762733,0.019486354875994212,0.5784922208777676,1.8136162149972994,-0.15476681385717422,0.8469920138668321,0.6056479018936,0.24689976348114367,0.19054865591249434,2.1039880520769403,-0.8851760478860837,-0.7287703736920425,0.19054865591249434,-0.5134593662434148,1.6412063989989234,0.7403936172598823,0.24689976348114367,2.6439590132330637,-1.2042581055902233,-1.075641485634037,-0.6977474581428348,-1.0118216311731156,-0.42252790140681873,-0.3025770869123972,-0.6977474581428348,-0.5745330198140897,1.789127256491963,-0.15476681385717422,-0.21360297580762733,-0.9167120699523604,-0.39240070950050854,0.16225002844017103,-0.8537243644783261,2.3648106652398435,-1.075641485634037,0.10540172980990664,-0.15476681385717422,0.7938228645047847,-1.5644818109642689,0.07685003800728503,1.6907038084850876,0.5784922208777676,-1.9338917553280288,0.358643578170959,-0.5439512892731678,-1.0118216311731156,-0.39240070950050854,0.13386805297961285,-0.6359637761900813,-0.4830577925150717,-0.36236611826561227,-0.2728238448155597,-0.0672262509964336,-0.36236611826561227,-1.7312845351077755,-0.09631286647900751,-1.8660637299899208,2.4584637978137454,-0.39240070950050854,0.8999061013249092,-0.980035309228183,0.9262690243148245,3.1201613747468726,0.13386805297961285,-0.009327790283860563,-0.4830577925150717,0.5239685462529114,1.1865840591524877,-0.33242471265450957,-0.1254926486793712,-2.104720346998251,0.6597506092154378,0.44164086630862914,0.048211934796472365,-0.33242471265450957,0.048211934796472365,-0.21360297580762733,0.13386805297961285,0.048211934796472365,-3.201984612157771,0.8469920138668321,1.5665946676492313,0.07685003800728503,0.358643578170959,0.5239685462529114,-0.038231613171792155,0.5784922208777676,1.6907038084850876,1.1349899370587961,1.031106974534266,0.49659904864423754,3.1424732722153843,1.2635525405656844,-0.4830577925150717,-0.18413660636999382,0.019486354875994212,0.358643578170959,0.4691567512932392,0.44164086630862914,2.0800297213070706,0.49659904864423754,0.6327337919013768,0.30292897251860446,-0.45274711809482365,0.44164086630862914,0.16225002844017103,0.4691567512932392,0.19054865591249434,-0.24316559991811548,0.19054865591249434,0.8999061013249092,2.317750661267261,-7.716267699270839,-0.18413660636999382,-0.21360297580762733,-0.21360297580762733,-0.82235748271142,0.5512660173470204,-0.7287703736920425,0.7403936172598823,0.873480632258922,0.24689976348114367,-1.1719828815512887,-1.0118216311731156,-0.948331973940958,-0.5745330198140897,-0.0672262509964336,-4.321506834636257,-0.24316559991811548,-1.8660637299899208,-1.2690482472817965,0.41405059073486755,-3.4952288779532705,-0.3025770869123972,0.9262690243148245,-0.21360297580762733,0.19054865591249434,-1.1719828815512887,0.713579835070738,0.4691567512932392,-1.075641485634037,0.8469920138668321,-0.5134593662434148,-0.0672262509964336,-0.36236611826561227,-0.24316559991811548,0.6597506092154378,0.27495414250230754,-4.783944066538735,-0.39240070950050854,-0.21360297580762733,-0.038231613171792155,0.019486354875994212,0.358643578170959,0.27495414250230754
| 3,375
|
Activation of immune response
| 16
| 51
| 2.492438
| 0.012687
|
P00813,Q7Z434,P49770,P04439,P12956,Q14699,Q16512,P46379,Q96EP0,Q96PK6,Q9UKG1,P17931,Q9NR50,Q9NUD5,Q9UHD2,Q07666
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,196,604,318,8,412,307,453,374,681,152,305,624,685,689,434
|
2984,2482,1891,900,1173,0,318,2030,1628,8,1267,2304,305,1841,952,1387,2309,2426,756,956,2585,453,604,2316,2683,1648,2550,671,434,2996,1717,873,2764,1855,412,1927,307,196,2567,374,681,2463,3137,2351,624,685,2409,689,1749,1485,152
|
-0.82235748271142,-0.42252790140681873,-0.15476681385717422,0.358643578170959,0.19054865591249434,8.05927987366474,1.004988400356168,-0.21360297580762733,-0.038231613171792155,4.85801582075318,0.13386805297961285,-0.33242471265450957,1.031106974534266,-0.1254926486793712,0.33082515613705404,0.07685003800728503,-0.33242471265450957,-0.39240070950050854,0.4691567512932392,0.33082515613705404,-0.4830577925150717,0.7938228645047847,0.6056479018936,-0.33242471265450957,-0.5439512892731678,-0.038231613171792155,-0.45274711809482365,0.5512660173470204,0.8204396326290617,-0.82235748271142,-0.0672262509964336,0.38638510613707605,-0.6052040240979027,-0.1254926486793712,0.8469920138668321,-0.15476681385717422,1.031106974534266,1.3654085471612543,-0.45274711809482365,0.8999061013249092,0.5512660173470204,-0.39240070950050854,-1.075641485634037,-0.33242471265450957,0.6056479018936,0.5512660173470204,-0.36236611826561227,0.5512660173470204,-0.0672262509964336,0.048211934796472365,1.6163849582577512
| 3,375
|
Mitochondrial envelope
| 55
| 339
| 2.490526
| 0.012755
|
P11310,O75880,O60830,Q13423,P00846,P12235,Q9BSK2,Q6P4A7,Q99497,P50416,Q9HCL2,Q9NS69,Q9H2D1,Q8WWC4,P03886,O43772,P23786,Q567V2,Q15388,O15121,Q6DKK2,Q69YU5,O43678,P14406,O43676,Q96RL7,Q6KCM7,Q9BYT8,P17931,P09001,O95563,Q70HW3,Q9NR28,Q99595,Q7Z434,Q9NZ45,P43304,Q13505,Q9BUK6,O95140,Q96CU9,Q9NVS2,O15228,Q8NI60,P30536,Q9Y2R0,Q8WY22,P53007,O14949,Q9NRA0,P82933,O43169,Q86UT6,Q96AY3,P53701
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,129,4,262,260,143,18,269,20,266,158,27,29,286,31,33,34,35,37,38,165,171,291,49,177,51,311,57,305,304,302,188,316,64,196,67,200,334,79,331,86,214,338,93,341,363,98,227,231,109,111,116,241,124,253
|
3153,1317,897,2103,3313,1687,3096,1216,231,38,338,1372,116,3231,1886,2665,177,291,33,385,945,2108,4,946,1321,1690,581,2297,947,2241,448,2948,1693,129,3126,698,1031,1891,331,493,1172,2029,901,302,2243,449,1695,1696,725,494,260,31,1493,1174,1073,1118,1265,304,949,993,1495,1564,2181,1,143,1122,3041,2986,49,3330,1175,1634,3201,305,1701,1217,2953,827,700,1329,2489,2539,909,1387,34,1177,2037,2584,3061,2674,341,1219,539,955,1331,2426,2369,1844,1181,3010,2122,1846,200,1847,2371,3045,3063,2756,2956,266,2720,1573,917,3183,2256,227,253,2318,1576,2758,1086,2681,2682,541,2260,1508,2549,1921,3049,2054,733,111,1509,432,2799,1649,2205,1281,999,1457,2442,3027,1391,262,334,3234,1392,1800,2207,1517,37,3205,2966,1519,1860,3365,1596,2212,2059,437,3105,768,35,2062,2969,1462,1231,3275,171,165,3051,311,2600,2806,269,2453,706,1138,2931,188,2142,1468,196,1233,241,1525,2562,2933,1932,924,1007,502,773,2563,1398,644,2269,563,2509,2846,1527,775,93,1814,1667,1869,3071,286,1238,1199,98,1528,1010,3189,1056,649,1532,124,619,2847,86,1098,2909,2650,1099,3136,2883,3107,2884,2735,51,2464,1243,20,1244,64,3137,465,932,2848,1674,651,18,2226,2700,79,3109,3373,359,2815,2605,2403,2404,1946,3272,3359,1819,3289,57,2468,3093,936,2817,29,2975,2608,715,622,819,1479,3248,2353,1480,2090,1308,1481,158,1416,717,718,654,2007,316,109,1156,977,27,1541,938,786,820,746,214,595,821,1543,787,1209,1210,67,2093,2010,2095,2096,3006,1418,747,400,687,2660,510,3076,1750,1485,3193,2235,857,3360,2290,363,1488,2099,2522,3276,793,3141,424,1753,2412,578,1066,3370,2524,2477,1423,1684,1548,943,427
|
-1.1397880951540584,0.10540172980990664,0.358643578170959,-0.24316559991811548,-2.104720346998251,-0.0672262509964336,-1.0118216311731156,0.16225002844017103,1.212296082730813,2.8043654472386006,0.952569994453112,0.07685003800728503,1.862456329832627,-1.4653079613874214,-0.15476681385717422,-0.5439512892731678,1.441240326714265,1.057165873125376,3.0081206146023467,0.873480632258922,0.33082515613705404,-0.24316559991811548,5.415645674566234,0.33082515613705404,0.10540172980990664,-0.0672262509964336,0.6327337919013768,-0.33242471265450957,0.33082515613705404,-0.3025770869123972,0.7938228645047847,-0.7910758719515134,-0.0672262509964336,1.7645918959276166,-1.075641485634037,0.5239685462529114,0.27495414250230754,-0.15476681385717422,0.978809595175081,0.7403936172598823,0.19054865591249434,-0.21360297580762733,0.358643578170959,1.031106974534266,-0.3025770869123972,0.7938228645047847,-0.0672262509964336,-0.0672262509964336,0.49659904864423754,0.7403936172598823,1.1349899370587961,3.030593559630485,0.019486354875994212,0.19054865591249434,0.24689976348114367,0.21876491453847344,0.13386805297961285,1.031106974534266,0.33082515613705404,0.30292897251860446,0.019486354875994212,-0.009327790283860563,-0.2728238448155597,7.367385577094042,1.6412063989989234,0.21876491453847344,-0.9167120699523604,-0.82235748271142,2.6209010513937283,-2.277316641610277,0.19054865591249434,-0.038231613171792155,-1.334155331699041,1.031106974534266,-0.0672262509964336,0.16225002844017103,-0.7910758719515134,0.41405059073486755,0.5239685462529114,0.10540172980990664,-0.42252790140681873,-0.45274711809482365,0.358643578170959,0.07685003800728503,2.985614892363513,0.19054865591249434,-0.21360297580762733,-0.4830577925150717,-0.948331973940958,-0.5439512892731678,0.952569994453112,0.16225002844017103,0.6866990592950521,0.33082515613705404,0.10540172980990664,-0.39240070950050854,-0.36236611826561227,-0.1254926486793712,0.19054865591249434,-0.8537243644783261,-0.24316559991811548,-0.1254926486793712,1.340025485497747,-0.1254926486793712,-0.36236611826561227,-0.9167120699523604,-0.948331973940958,-0.6052040240979027,-0.7910758719515134,1.1091068208502726,-0.5745330198140897,-0.009327790283860563,0.358643578170959,-1.2366133611756898,-0.3025770869123972,1.2379520800421246,1.1608155122181425,-0.33242471265450957,-0.009327790283860563,-0.6052040240979027,0.24689976348114367,-0.5439512892731678,-0.5439512892731678,0.6866990592950521,-0.3025770869123972,0.019486354875994212,-0.45274711809482365,-0.15476681385717422,-0.9167120699523604,-0.21360297580762733,0.49659904864423754,1.9111150023933372,0.019486354875994212,0.8204396326290617,-0.6359637761900813,-0.038231613171792155,-0.2728238448155597,0.13386805297961285,0.30292897251860446,0.048211934796472365,-0.39240070950050854,-0.8851760478860837,0.07685003800728503,1.1349899370587961,0.978809595175081,-1.4982894378117122,0.07685003800728503,-0.09631286647900751,-0.2728238448155597,0.019486354875994212,2.84988124164933,-1.334155331699041,-0.7910758719515134,0.019486354875994212,-0.1254926486793712,-4.017752483133644,-0.009327790283860563,-0.2728238448155597,-0.21360297580762733,0.8204396326290617,-1.0118216311731156,0.4691567512932392,2.985614892363513,-0.21360297580762733,-0.7910758719515134,0.048211934796472365,0.16225002844017103,-1.7648689174206336,1.491534732272122,1.516605184692839,-0.9167120699523604,1.031106974534266,-0.4830577925150717,-0.6359637761900813,1.1091068208502726,-0.39240070950050854,0.5239685462529114,0.21876491453847344,-0.7598800080904538,1.39073841091754,-0.24316559991811548,0.048211934796472365,1.3654085471612543,0.16225002844017103,1.1865840591524877,0.019486354875994212,-0.45274711809482365,-0.7598800080904538,-0.15476681385717422,0.358643578170959,0.30292897251860446,0.7403936172598823,0.4691567512932392,-0.45274711809482365,0.07685003800728503,0.5784922208777676,-0.3025770869123972,0.6597506092154378,-0.42252790140681873,-0.6668117578076647,0.019486354875994212,0.4691567512932392,2.0560289253619395,-0.09631286647900751,-0.038231613171792155,-0.1254926486793712,-0.948331973940958,1.0831656426328216,0.16225002844017103,0.19054865591249434,2.0078987123817007,0.019486354875994212,0.30292897251860446,-1.2366133611756898,0.27495414250230754,0.5784922208777676,0.019486354875994212,1.8136162149972994,0.6056479018936,-0.6668117578076647,2.1039880520769403,0.24689976348114367,-0.7287703736920425,-0.5134593662434148,0.24689976348114367,-1.075641485634037,-0.6977474581428348,-1.0118216311731156,-0.6977474581428348,-0.5745330198140897,2.5746757906678,-0.39240070950050854,0.16225002844017103,3.582293433383776,0.16225002844017103,2.3648106652398435,-1.075641485634037,0.7938228645047847,0.358643578170959,-0.6668117578076647,-0.038231613171792155,0.5784922208777676,3.6904267756578513,-0.2728238448155597,-0.5439512892731678,2.199402700232554,-1.0118216311731156,-10.434186732673757,0.9262690243148245,-0.6359637761900813,-0.4830577925150717,-0.36236611826561227,-0.36236611826561227,-0.15476681385717422,-1.7312845351077755,-3.458357365309315,-0.09631286647900751,-1.8660637299899208,2.4584637978137454,-0.39240070950050854,-0.980035309228183,0.358643578170959,-0.6359637761900813,3.1201613747468726,-0.7910758719515134,-0.4830577925150717,0.5239685462529114,0.6056479018936,0.44164086630862914,0.048211934796472365,-1.5644818109642689,-0.33242471265450957,0.048211934796472365,-0.21360297580762733,0.13386805297961285,0.048211934796472365,1.5665946676492313,0.07685003800728503,0.5239685462529114,0.5239685462529114,0.5784922208777676,-0.18413660636999382,1.031106974534266,1.935377141239234,0.21876491453847344,0.33082515613705404,3.1424732722153843,0.019486354875994212,0.358643578170959,0.4691567512932392,0.44164086630862914,0.49659904864423754,1.2890979463364292,0.6327337919013768,0.44164086630862914,0.019486354875994212,0.4691567512932392,0.19054865591249434,0.19054865591249434,2.317750661267261,-0.21360297580762733,-0.18413660636999382,-0.21360297580762733,-0.21360297580762733,-0.82235748271142,0.07685003800728503,0.49659904864423754,0.873480632258922,0.5512660173470204,-0.5134593662434148,0.7403936172598823,-0.948331973940958,-0.0672262509964336,0.048211934796472365,-1.2690482472817965,-0.2728238448155597,0.41405059073486755,-3.4952288779532705,-0.3025770869123972,0.9262690243148245,0.048211934796472365,-0.21360297580762733,-0.42252790140681873,-1.7648689174206336,0.4691567512932392,-1.075641485634037,0.8469920138668321,-0.0672262509964336,-0.36236611826561227,0.6597506092154378,0.27495414250230754,-4.783944066538735,-0.42252790140681873,-0.39240070950050854,0.07685003800728503,-0.038231613171792155,0.019486354875994212,0.358643578170959,0.8469920138668321
| 3,375
|
Negative regulation of extrinsic apoptotic signaling pathway
| 6
| 24
| 2.488077
| 0.012844
|
P49841,Q99504,P42858,Q99497,P17931,Q8WWQ0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,229,175,20,305,126
|
1428,2112,3079,993,1899,305,2038,1781,2792,175,1848,342,32,959,1281,528,2135,2218,881,126,2512,20,229,1207
|
0.048211934796472365,-0.24316559991811548,-0.980035309228183,0.30292897251860446,-0.15476681385717422,1.031106974534266,-0.21360297580762733,-0.09631286647900751,-0.6359637761900813,1.4664132535336514,-0.1254926486793712,0.952569994453112,3.030593559630485,0.33082515613705404,0.13386805297961285,0.713579835070738,-0.24316559991811548,-0.2728238448155597,0.38638510613707605,1.789127256491963,-0.42252790140681873,3.582293433383776,1.2379520800421246,0.19054865591249434
| 3,375
|
Monocarboxylic acid metabolic process
| 26
| 161
| 2.486853
| 0.012888
|
P11310,O75521,Q8N8N7,P48735,Q16836,Q99497,P50416,Q9HCL2,Q9UKG9,P31751,P23786,O15121,O95563,Q9H2C2,P09455,O94788,Q9BY49,P30084,Q9BWD1,Q15120,O75874,P14174,Q15800,P07099,Q9BRR6,O14734
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,132,5,11,15,20,266,158,160,154,34,38,302,66,319,75,203,204,88,90,95,101,234,113,118,237
|
428,1316,697,1687,2237,898,237,627,38,338,1371,1372,1028,1491,2108,751,2531,2711,132,753,1693,95,75,2298,990,1766,302,2243,1768,1896,2244,1697,2825,2712,1322,2713,2113,602,2361,1699,113,1118,1561,3142,1771,319,1326,1074,2114,1772,1,2115,1075,2630,101,3009,1773,2830,3331,994,663,1077,2715,1217,700,908,2118,634,34,2368,1446,557,1218,204,154,955,407,2369,2493,2678,3211,2122,408,1571,1040,913,11,1041,2756,1336,266,606,2048,410,475,1975,1642,917,1976,2127,2758,1787,2796,2055,1649,3068,1716,673,3366,2505,737,3104,90,2766,234,1519,1348,1051,15,3347,2599,500,2267,2216,2931,3239,2602,1053,814,5,3279,776,1528,1999,2076,1202,741,2082,2347,20,2974,118,3373,88,203,66,572,819,3273,158,2007,785,3169,2613,1683,1544,1249,822,160,1163,2823
|
0.8204396326290617,0.10540172980990664,0.5239685462529114,-0.0672262509964336,-0.3025770869123972,0.358643578170959,1.1865840591524877,0.5784922208777676,2.8043654472386006,0.952569994453112,0.07685003800728503,0.07685003800728503,0.27495414250230754,0.019486354875994212,-0.24316559991811548,0.4691567512932392,-0.45274711809482365,-0.5745330198140897,1.7400097763933111,0.4691567512932392,-0.0672262509964336,2.031985358818018,2.223153155757611,-0.33242471265450957,0.30292897251860446,-0.09631286647900751,1.031106974534266,-0.3025770869123972,-0.09631286647900751,-0.15476681385717422,-0.3025770869123972,-0.0672262509964336,-0.6668117578076647,-0.5745330198140897,0.10540172980990664,-0.5745330198140897,-0.24316559991811548,0.6056479018936,-0.36236611826561227,-0.0672262509964336,1.8868081766093292,0.21876491453847344,-0.009327790283860563,-1.1076741576662066,-0.09631286647900751,1.004988400356168,0.10540172980990664,0.24689976348114367,-0.24316559991811548,-0.09631286647900751,7.367385577094042,-0.24316559991811548,0.24689976348114367,-0.5134593662434148,1.983768672818817,-0.8537243644783261,-0.09631286647900751,-0.6668117578076647,-2.3120448145541554,0.30292897251860446,0.5512660173470204,0.24689976348114367,-0.5745330198140897,0.16225002844017103,0.5239685462529114,0.358643578170959,-0.24316559991811548,0.5784922208777676,2.985614892363513,-0.36236611826561227,0.048211934796472365,0.6597506092154378,0.16225002844017103,1.3145887721057432,1.5665946676492313,0.33082515613705404,0.8469920138668321,-0.36236611826561227,-0.42252790140681873,-0.5439512892731678,-1.3668267524146023,-0.24316559991811548,0.8469920138668321,-0.009327790283860563,0.27495414250230754,0.358643578170959,4.470238014994655,0.27495414250230754,-0.6052040240979027,0.10540172980990664,1.1091068208502726,0.6056479018936,-0.21360297580762733,0.8469920138668321,0.7671410746721091,-0.18413660636999382,-0.038231613171792155,0.358643578170959,-0.18413660636999382,-0.24316559991811548,-0.6052040240979027,-0.09631286647900751,-0.6359637761900813,-0.21360297580762733,-0.038231613171792155,-0.948331973940958,-0.0672262509964336,0.5512660173470204,-4.055519423800208,-0.42252790140681873,0.49659904864423754,-1.0118216311731156,2.0800297213070706,-0.6052040240979027,1.212296082730813,0.019486354875994212,0.10540172980990664,0.27495414250230754,3.797869337859779,-2.7696897938215086,-0.4830577925150717,0.7403936172598823,-0.3025770869123972,-0.2728238448155597,-0.7598800080904538,-1.5313475075418816,-0.4830577925150717,0.27495414250230754,0.44164086630862914,5.317208932732073,-1.7985271289035507,0.4691567512932392,0.019486354875994212,-0.18413660636999382,-0.21360297580762733,0.19054865591249434,0.49659904864423754,-0.21360297580762733,-0.33242471265450957,3.582293433383776,-0.7910758719515134,1.862456329832627,-10.434186732673757,2.1039880520769403,1.340025485497747,2.341300334418682,0.6597506092154378,0.44164086630862914,-1.7312845351077755,1.5665946676492313,-0.18413660636999382,0.4691567512932392,-1.1719828815512887,-0.4830577925150717,-0.038231613171792155,0.019486354875994212,0.16225002844017103,0.44164086630862914,1.5665946676492313,0.21876491453847344,-0.6359637761900813
| 3,375
|
Phosphoric ester hydrolase activity
| 13
| 66
| 2.485324
| 0.012943
|
Q9UNI6,P49902,Q08623,Q9NPH0,Q8IV08,Q99504,Q9BRF8,Q13555,Q9H857,Q9NX62,Q9ULE6,Q86UY8,Q96PE3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
402,343,162,2,3,229,39,355,445,215,225,122,94
|
1367,3021,1689,2112,1627,2179,949,993,3306,1701,1841,1038,2190,910,1567,3061,343,2316,2126,1575,866,2836,2377,526,2898,2056,1049,162,999,2132,355,1924,2597,3147,1803,437,838,1993,122,3,3259,3071,2566,617,1355,2883,94,229,1673,39,1302,2657,2405,1614,445,846,1742,1679,2,2007,2283,215,655,225,402,692
|
0.07685003800728503,-0.8851760478860837,-0.0672262509964336,-0.24316559991811548,-0.038231613171792155,-0.2728238448155597,0.33082515613705404,0.30292897251860446,-2.036174700270587,-0.0672262509964336,-0.1254926486793712,0.27495414250230754,-0.2728238448155597,0.358643578170959,-0.009327790283860563,-0.948331973940958,0.952569994453112,-0.33242471265450957,-0.24316559991811548,-0.009327790283860563,0.38638510613707605,-0.6668117578076647,-0.36236611826561227,0.713579835070738,-0.7287703736920425,-0.21360297580762733,0.27495414250230754,1.516605184692839,0.30292897251860446,-0.24316559991811548,0.9262690243148245,-0.15476681385717422,-0.4830577925150717,-1.1076741576662066,-0.09631286647900751,0.8204396326290617,0.41405059073486755,-0.18413660636999382,1.8136162149972994,5.727500366668169,-1.6643385894420446,-0.948331973940958,-0.45274711809482365,0.6056479018936,0.10540172980990664,-0.6977474581428348,2.0560289253619395,1.2379520800421246,-0.038231613171792155,2.7815557604620307,0.13386805297961285,-0.5134593662434148,-0.36236611826561227,-0.009327790283860563,0.8204396326290617,0.41405059073486755,-0.0672262509964336,-0.038231613171792155,6.8766404995232415,-0.18413660636999382,-0.3025770869123972,1.2890979463364292,0.5784922208777676,1.2635525405656844,0.873480632258922,0.5512660173470204
| 3,375
|
Ubiquitin ligase complex
| 19
| 66
| 2.479494
| 0.013157
|
Q8IVV7,Q8N668,Q14999,Q96BN8,O95155,Q12834,Q14145,Q96K76,Q9UBV2,Q9NXR7,Q5TAQ9,Q9NV06,Q9H3F6,Q9NXV2,Q9UJX3,Q12933,Q9NT62,Q96EP0,Q96S59
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
397,285,149,417,42,294,182,63,198,337,77,208,481,485,486,96,361,374,243
|
722,1378,1170,1763,2177,42,2856,1124,473,2683,1978,2590,2548,294,96,2381,2328,2555,2264,2556,182,149,837,2871,1135,1290,77,2970,1526,397,285,1012,1057,417,2811,374,2697,63,1406,243,1818,2515,3210,481,1876,2089,1415,2230,361,208,337,485,1823,198,891,1311,486,1364,2470,1064,3302,3241,1954,1955,942,1832
|
0.49659904864423754,0.07685003800728503,0.19054865591249434,-0.09631286647900751,-0.2728238448155597,2.7129169777181765,-0.6977474581428348,0.21876491453847344,0.7671410746721091,-0.5439512892731678,-0.18413660636999382,-0.4830577925150717,-0.45274711809482365,1.057165873125376,2.031985358818018,-0.36236611826561227,-0.33242471265450957,-0.45274711809482365,-0.3025770869123972,-0.45274711809482365,1.416015523904057,1.6163849582577512,0.41405059073486755,-0.6977474581428348,0.21876491453847344,0.13386805297961285,2.223153155757611,-0.7910758719515134,0.019486354875994212,0.873480632258922,1.0831656426328216,0.30292897251860446,0.27495414250230754,0.8469920138668321,-0.6359637761900813,0.8999061013249092,-0.5439512892731678,2.3648106652398435,0.07685003800728503,1.1865840591524877,-0.09631286647900751,-0.42252790140681873,-1.334155331699041,0.7671410746721091,-0.1254926486793712,-0.21360297580762733,0.07685003800728503,-0.2728238448155597,0.9262690243148245,1.3145887721057432,0.978809595175081,0.7671410746721091,-0.09631286647900751,1.3654085471612543,0.38638510613707605,0.13386805297961285,0.7671410746721091,0.10540172980990664,-0.39240070950050854,0.27495414250230754,-1.9338917553280288,-1.5313475075418816,-0.15476681385717422,-0.15476681385717422,0.358643578170959,-0.09631286647900751
| 3,375
|
Hepaticobiliary system development
| 8
| 33
| 2.478713
| 0.013186
|
P00813,P11310,P35610,O94788,Q6KC79,Q15418,P50416,Q14103
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,407,75,456,53,266,240
|
697,579,2238,471,75,0,2825,3237,1493,993,1,3192,1632,2987,1498,2368,1703,407,266,1184,2379,2263,2264,240,53,1051,456,1869,1937,1941,1538,3324,688
|
0.5239685462529114,0.6327337919013768,-0.3025770869123972,0.7671410746721091,2.223153155757611,8.05927987366474,-0.6668117578076647,-1.5313475075418816,0.019486354875994212,0.30292897251860446,7.367385577094042,-1.2690482472817965,-0.038231613171792155,-0.82235748271142,0.019486354875994212,-0.36236611826561227,-0.0672262509964336,0.8469920138668321,1.1091068208502726,0.19054865591249434,-0.36236611826561227,-0.3025770869123972,-0.3025770869123972,1.1865840591524877,2.4817813149505383,0.27495414250230754,0.7938228645047847,-0.1254926486793712,-0.15476681385717422,-0.15476681385717422,0.019486354875994212,-2.1390993722008798,0.5512660173470204
| 3,375
|
Nucleotide transmembrane transporter activity
| 6
| 13
| 2.476178
| 0.01328
|
P41440,P12235,Q9BSK2,Q6KCM7,Q9H2D1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
321,143,18,311,29,546
|
628,1491,1174,143,1122,321,311,2600,1525,546,18,29,1481
|
0.5784922208777676,0.019486354875994212,0.19054865591249434,1.6412063989989234,0.21876491453847344,1.004988400356168,1.031106974534266,-0.4830577925150717,0.019486354875994212,0.6866990592950521,3.6904267756578513,3.1201613747468726,0.048211934796472365
| 3,375
|
Organophosphate ester transmembrane transporter activity
| 6
| 13
| 2.476178
| 0.01328
|
P41440,P12235,Q9BSK2,Q6KCM7,Q9H2D1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
321,143,18,311,29,546
|
628,1491,1174,143,1122,321,311,2600,1525,546,18,29,1481
|
0.5784922208777676,0.019486354875994212,0.19054865591249434,1.6412063989989234,0.21876491453847344,1.004988400356168,1.031106974534266,-0.4830577925150717,0.019486354875994212,0.6866990592950521,3.6904267756578513,3.1201613747468726,0.048211934796472365
| 3,375
|
Positive regulation of cell activation
| 7
| 45
| 2.471143
| 0.013468
|
P00813,P49366,P14174,P12956,Q9NRA0,Q15418,P30825
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,130,101,8,109,53,26
|
1834,2022,3305,1374,1173,1895,2857,0,3236,2825,318,1628,2181,3327,8,101,1269,1387,26,756,865,130,831,3257,1648,2056,2996,527,2502,1515,3156,2446,53,1861,1660,1863,2338,3286,2146,504,1533,158,2231,109,3057
|
-0.1254926486793712,-0.21360297580762733,-2.0020086776833446,0.07685003800728503,0.19054865591249434,-0.15476681385717422,-0.6977474581428348,8.05927987366474,-1.5313475075418816,-0.6668117578076647,1.004988400356168,-0.038231613171792155,-0.2728238448155597,-2.242657726526616,4.85801582075318,1.983768672818817,0.13386805297961285,0.07685003800728503,3.164753514554234,0.4691567512932392,0.38638510613707605,1.7645918959276166,0.41405059073486755,-1.6643385894420446,-0.038231613171792155,-0.21360297580762733,-0.82235748271142,0.713579835070738,-0.42252790140681873,0.019486354875994212,-1.1397880951540584,-0.39240070950050854,2.4817813149505383,-0.1254926486793712,-0.038231613171792155,-0.1254926486793712,-0.33242471265450957,-1.8660637299899208,-0.24316559991811548,0.7403936172598823,0.019486354875994212,1.5665946676492313,-0.2728238448155597,1.935377141239234,-0.9167120699523604
| 3,375
|
Early endosome membrane
| 12
| 46
| 2.466655
| 0.013638
|
Q8IV08,Q7Z3T8,P04439,Q9HC07,Q9UJY4,Q86YV9,Q15276,Q8N4V1,Q9UKG1,P42566,Q96L92,Q96PE3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
3,395,318,139,279,460,176,81,152,265,87,94
|
1165,2294,2781,1319,2175,2240,2825,318,452,3042,1328,265,1450,2895,1711,1184,2898,2503,2506,176,2870,766,395,771,1931,460,3,81,842,1817,87,94,1203,2814,2084,2607,592,1949,139,1824,279,3036,152,1622,2981,1489
|
0.19054865591249434,-0.33242471265450957,-0.6359637761900813,0.10540172980990664,-0.2728238448155597,-0.3025770869123972,-0.6668117578076647,1.004988400356168,0.7938228645047847,-0.9167120699523604,0.10540172980990664,1.1091068208502726,0.048211934796472365,-0.7287703736920425,-0.0672262509964336,0.19054865591249434,-0.7287703736920425,-0.42252790140681873,-0.42252790140681873,1.4664132535336514,-0.6977474581428348,0.4691567512932392,0.873480632258922,0.4691567512932392,-0.15476681385717422,0.7938228645047847,5.727500366668169,2.1517785208460363,0.41405059073486755,-0.09631286647900751,2.1039880520769403,2.0560289253619395,0.19054865591249434,-0.6359637761900813,-0.21360297580762733,-0.4830577925150717,0.6327337919013768,-0.15476681385717422,1.6907038084850876,-0.09631286647900751,1.1091068208502726,-0.8851760478860837,1.6163849582577512,-0.009327790283860563,-0.7910758719515134,0.048211934796472365
| 3,375
|
Regulation of cell activation
| 14
| 72
| 2.465886
| 0.013667
|
P00813,P49366,P14174,Q9BWH2,Q9HCL2,P12956,P04439,Q16512,Q9NRA0,O15360,Q15418,P17931,P30825,O96005
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,130,101,359,158,8,318,307,109,115,53,305,26,283
|
1834,2022,2622,115,3305,1374,1173,283,1895,2857,0,3236,2825,318,1628,993,2031,2181,1631,3327,8,101,1269,1634,305,1387,26,1781,1179,756,729,865,1848,130,2316,831,3257,1648,2056,2996,527,2502,2132,1515,1089,3156,2446,53,876,307,1861,1660,1863,2338,611,2396,3286,776,2146,2511,1012,504,2150,1533,1817,359,419,158,2231,109,3057,2983
|
-0.1254926486793712,-0.21360297580762733,-0.5134593662434148,1.862456329832627,-2.0020086776833446,0.07685003800728503,0.19054865591249434,1.0831656426328216,-0.15476681385717422,-0.6977474581428348,8.05927987366474,-1.5313475075418816,-0.6668117578076647,1.004988400356168,-0.038231613171792155,0.30292897251860446,-0.21360297580762733,-0.2728238448155597,-0.038231613171792155,-2.242657726526616,4.85801582075318,1.983768672818817,0.13386805297961285,-0.038231613171792155,1.031106974534266,0.07685003800728503,3.164753514554234,-0.09631286647900751,0.19054865591249434,0.4691567512932392,0.49659904864423754,0.38638510613707605,-0.1254926486793712,1.7645918959276166,-0.33242471265450957,0.41405059073486755,-1.6643385894420446,-0.038231613171792155,-0.21360297580762733,-0.82235748271142,0.713579835070738,-0.42252790140681873,-0.24316559991811548,0.019486354875994212,0.24689976348114367,-1.1397880951540584,-0.39240070950050854,2.4817813149505383,0.38638510613707605,1.031106974534266,-0.1254926486793712,-0.038231613171792155,-0.1254926486793712,-0.33242471265450957,0.6056479018936,-0.36236611826561227,-1.8660637299899208,0.4691567512932392,-0.24316559991811548,-0.42252790140681873,0.30292897251860446,0.7403936172598823,-0.24316559991811548,0.019486354875994212,-0.09631286647900751,0.9262690243148245,0.8469920138668321,1.5665946676492313,-0.2728238448155597,1.935377141239234,-0.9167120699523604,-0.7910758719515134
| 3,375
|
Nucleotide transmembrane transport
| 6
| 11
| 2.460188
| 0.013886
|
P41440,P12235,Q9BSK2,Q8TDW0,Q9H2D1,Q8TB61
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
321,143,18,312,29,546
|
628,1491,1174,143,1122,321,1525,546,312,18,29
|
0.5784922208777676,0.019486354875994212,0.19054865591249434,1.6412063989989234,0.21876491453847344,1.004988400356168,0.019486354875994212,0.6866990592950521,1.031106974534266,3.6904267756578513,3.1201613747468726
| 3,375
|
Anion transmembrane transporter activity
| 14
| 48
| 2.452138
| 0.014201
|
Q9UBX3,P53007,O15439,O00299,P41440,P0CG08,O95563,P12235,Q8TDW0,Q6KCM7,P08195,P30825,Q9H2D1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
400,227,628,625,321,662,302,143,312,311,252,26,29,546
|
625,2104,628,1167,1491,1693,302,1174,252,662,1900,143,1122,700,26,321,1847,1183,227,1916,2128,2205,2386,1595,2335,311,2644,2600,2267,1525,546,312,2735,1608,2848,2228,29,1479,2353,1481,2355,400,1750,857,2619,1423,1424,1685
|
0.5784922208777676,-0.24316559991811548,0.5784922208777676,0.19054865591249434,0.019486354875994212,-0.0672262509964336,1.031106974534266,0.19054865591249434,1.1608155122181425,0.5512660173470204,-0.15476681385717422,1.6412063989989234,0.21876491453847344,0.5239685462529114,3.164753514554234,1.004988400356168,-0.1254926486793712,0.19054865591249434,1.2379520800421246,-0.15476681385717422,-0.24316559991811548,-0.2728238448155597,-0.36236611826561227,-0.009327790283860563,-0.33242471265450957,1.031106974534266,-0.5134593662434148,-0.4830577925150717,-0.3025770869123972,0.019486354875994212,0.6866990592950521,1.031106974534266,-0.5745330198140897,-0.009327790283860563,-0.6668117578076647,-0.2728238448155597,3.1201613747468726,0.048211934796472365,-0.33242471265450957,0.048211934796472365,-0.33242471265450957,0.873480632258922,-0.0672262509964336,0.41405059073486755,-0.4830577925150717,0.07685003800728503,0.07685003800728503,-0.038231613171792155
| 3,375
|
Ventricular arrhythmia
| 8
| 39
| 2.445988
| 0.014446
|
O43772,P23786,Q96RR1,P00846,P12235,Q02487,Q03001,P03886
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
33,34,219,260,143,80,17,31
|
33,3161,581,800,494,260,3079,31,948,1325,2536,1495,1383,143,2859,3025,495,1329,34,1181,2493,1911,1912,757,2756,605,1575,80,17,1283,2642,272,1870,2078,816,219,3138,1102,821
|
3.0081206146023467,-1.1719828815512887,0.6327337919013768,0.44164086630862914,0.7403936172598823,1.1349899370587961,-0.980035309228183,3.030593559630485,0.33082515613705404,0.10540172980990664,-0.45274711809482365,0.019486354875994212,0.07685003800728503,1.6412063989989234,-0.6977474581428348,-0.8851760478860837,0.7403936172598823,0.10540172980990664,2.985614892363513,0.19054865591249434,-0.42252790140681873,-0.15476681385717422,-0.15476681385717422,0.4691567512932392,-0.6052040240979027,0.6056479018936,-0.009327790283860563,2.1756112509536085,3.7334856981138764,0.13386805297961285,-0.5134593662434148,1.1091068208502726,-0.1254926486793712,-0.21360297580762733,0.44164086630862914,1.2635525405656844,-1.075641485634037,0.24689976348114367,0.44164086630862914
| 3,375
|
Kinase
| 38
| 115
| 2.444204
| 0.014517
|
Q13546,P11802,P41240,O14936,Q4G0N4,Q53H12,Q9UHD2,P31751,P49841,Q14012,P04183,P27144,Q16512,O00443,Q99640,Q15418,Q13131,P49840,Q9Y223,Q9Y3D8,O14976,P55263,O14578,O14757,Q13572,Q9BVS4,Q15120,Q9UBF8,Q8NI60,O43252,O43683,Q13464,Q9HA64,Q13555,Q9NRA0,Q9BRR6,P24941,P51812
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
528,633,756,383,23,768,689,154,32,810,801,664,307,795,444,53,673,805,720,329,191,193,579,330,585,742,90,747,93,469,470,104,236,355,109,118,367,239
|
795,1429,579,330,383,191,469,2984,470,1378,2577,2670,2244,1961,801,1698,1561,1631,633,1441,904,3041,1773,2788,1634,2364,1077,1217,1386,1498,1445,2186,1176,367,664,2189,2309,2861,154,1178,3116,1500,756,1846,995,805,32,2254,3250,2048,239,917,958,2318,1576,193,2376,1454,1648,1280,1047,2055,872,2550,2899,2442,673,873,2764,807,104,2927,528,355,585,810,3104,90,2690,2139,53,307,1859,1348,3167,23,768,2392,2454,1664,2562,93,967,2001,2272,1013,1476,1940,444,2514,118,1409,742,2656,1153,2351,236,109,2408,747,689,1881,720,329,1955
|
0.44164086630862914,0.048211934796472365,0.6327337919013768,0.978809595175081,0.873480632258922,1.3654085471612543,0.7671410746721091,-0.82235748271142,0.7671410746721091,0.07685003800728503,-0.4830577925150717,-0.5439512892731678,-0.3025770869123972,-0.18413660636999382,0.44164086630862914,-0.0672262509964336,-0.009327790283860563,-0.038231613171792155,0.5784922208777676,0.048211934796472365,0.358643578170959,-0.9167120699523604,-0.09631286647900751,-0.6359637761900813,-0.038231613171792155,-0.36236611826561227,0.24689976348114367,0.16225002844017103,0.07685003800728503,0.019486354875994212,0.048211934796472365,-0.2728238448155597,0.19054865591249434,0.8999061013249092,0.5512660173470204,-0.2728238448155597,-0.33242471265450957,-0.6977474581428348,1.5665946676492313,0.19054865591249434,-1.04369050099163,0.019486354875994212,0.4691567512932392,-0.1254926486793712,0.30292897251860446,0.44164086630862914,3.030593559630485,-0.3025770869123972,-1.5976919926421527,-0.21360297580762733,1.1865840591524877,0.358643578170959,0.33082515613705404,-0.33242471265450957,-0.009327790283860563,1.3654085471612543,-0.36236611826561227,0.048211934796472365,-0.038231613171792155,0.13386805297961285,0.27495414250230754,-0.21360297580762733,0.38638510613707605,-0.45274711809482365,-0.7287703736920425,-0.39240070950050854,0.5512660173470204,0.38638510613707605,-0.6052040240979027,0.44164086630862914,1.9595949228824863,-0.7598800080904538,0.713579835070738,0.9262690243148245,0.6327337919013768,0.44164086630862914,-1.0118216311731156,2.0800297213070706,-0.5439512892731678,-0.24316559991811548,2.4817813149505383,1.031106974534266,-0.1254926486793712,0.10540172980990664,-1.1719828815512887,3.4077973078556516,0.4691567512932392,-0.36236611826561227,-0.39240070950050854,-0.038231613171792155,-0.45274711809482365,2.0560289253619395,0.33082515613705404,-0.18413660636999382,-0.3025770869123972,0.30292897251860446,0.048211934796472365,-0.15476681385717422,0.8204396326290617,-0.42252790140681873,1.862456329832627,0.07685003800728503,0.49659904864423754,-0.5134593662434148,0.21876491453847344,-0.33242471265450957,1.212296082730813,1.935377141239234,-0.36236611826561227,0.49659904864423754,0.5512660173470204,-0.1254926486793712,0.5239685462529114,1.004988400356168,-0.15476681385717422
| 3,375
|
Iron ion binding
| 9
| 24
| 2.440611
| 0.014662
|
Q32P28,O00469,Q15800,O15460,P13674,Q16850,Q6UW02,Q9NVH6,Q8N543
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,280,234,74,76,82,58,91,123
|
280,2237,74,859,76,909,665,1220,1339,1455,234,82,65,2907,58,3239,123,1941,358,3280,3073,2280,91,2778
|
1.0831656426328216,-0.3025770869123972,2.223153155757611,0.38638510613707605,2.223153155757611,0.358643578170959,0.5512660173470204,0.16225002844017103,0.10540172980990664,0.048211934796472365,1.212296082730813,2.1279042192938276,2.341300334418682,-0.7287703736920425,2.435108227632791,-1.5313475075418816,1.8136162149972994,-0.15476681385717422,0.9262690243148245,-1.7985271289035507,-0.948331973940958,-0.3025770869123972,2.0800297213070706,-0.6052040240979027
| 3,375
|
Dephosphorylation
| 20
| 97
| 2.437989
| 0.014769
|
Q9UNI6,Q9NPH0,P49841,Q16537,Q08623,Q9BRF8,O75663,Q86XL3,P42858,Q9H857,P17931,P63167,Q9NX62,Q9ULE6,Q96PE3,P49902,Q99504,Q13464,Q13555,Q86UY8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
402,2,32,155,162,39,292,44,175,445,305,323,215,225,94,343,229,104,355,122
|
1367,3021,2945,1689,513,2577,292,2112,1627,1962,948,2179,2180,1495,3306,1036,1269,305,1701,1038,2188,1567,728,3061,3062,1846,175,1128,32,343,2316,2126,1575,866,2836,2377,2378,870,323,998,1453,526,2898,2056,1049,162,999,2132,3309,104,355,1924,2597,2209,3147,155,437,2767,838,2450,2066,1993,122,44,3264,3259,3071,2566,926,617,1355,2272,2883,1937,2275,94,229,1673,39,1302,2657,2405,1614,445,846,1742,1679,2,2007,3034,2283,215,3140,791,225,402,2014
|
0.07685003800728503,-0.8851760478860837,-0.7910758719515134,-0.0672262509964336,0.713579835070738,-0.4830577925150717,1.057165873125376,-0.24316559991811548,-0.038231613171792155,-0.18413660636999382,0.33082515613705404,-0.2728238448155597,-0.2728238448155597,0.019486354875994212,-2.036174700270587,0.27495414250230754,0.13386805297961285,1.031106974534266,-0.0672262509964336,0.27495414250230754,-0.2728238448155597,-0.009327790283860563,0.49659904864423754,-0.948331973940958,-0.948331973940958,-0.1254926486793712,1.4664132535336514,0.21876491453847344,3.030593559630485,0.952569994453112,-0.33242471265450957,-0.24316559991811548,-0.009327790283860563,0.38638510613707605,-0.6668117578076647,-0.36236611826561227,-0.36236611826561227,0.38638510613707605,1.004988400356168,0.30292897251860446,0.048211934796472365,0.713579835070738,-0.7287703736920425,-0.21360297580762733,0.27495414250230754,1.516605184692839,0.30292897251860446,-0.24316559991811548,-2.0704120237229517,1.9595949228824863,0.9262690243148245,-0.15476681385717422,-0.4830577925150717,-0.2728238448155597,-1.1076741576662066,1.5665946676492313,0.8204396326290617,-0.6052040240979027,0.41405059073486755,-0.39240070950050854,-0.21360297580762733,-0.18413660636999382,1.8136162149972994,2.689966750135784,-1.6977743138917556,-1.6643385894420446,-0.948331973940958,-0.45274711809482365,0.358643578170959,0.6056479018936,0.10540172980990664,-0.3025770869123972,-0.6977474581428348,-0.15476681385717422,-0.3025770869123972,2.0560289253619395,1.2379520800421246,-0.038231613171792155,2.7815557604620307,0.13386805297961285,-0.5134593662434148,-0.36236611826561227,-0.009327790283860563,0.8204396326290617,0.41405059073486755,-0.0672262509964336,-0.038231613171792155,6.8766404995232415,-0.18413660636999382,-0.8851760478860837,-0.3025770869123972,1.2890979463364292,-1.075641485634037,0.4691567512932392,1.2635525405656844,0.873480632258922,-0.18413660636999382
| 3,375
|
Anion transport
| 23
| 75
| 2.437398
| 0.014793
|
Q9UBX3,Q13546,O15439,O00299,Q9UHG3,P12235,O60831,P30825,Q9H2D1,Q8TB61,Q9Y5P4,P0CG08,Q8TDW0,Q6KCM7,Q13131,O95563,Q9Y4C2,O43865,P41440,P30536,P53007,P14174,P08195
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
400,528,628,625,13,143,514,26,29,546,694,662,312,311,673,302,599,69,321,341,227,101,252
|
625,2104,3242,628,1167,1491,69,514,1693,1436,302,2825,1174,1263,2924,2894,252,662,1900,143,1122,101,700,1218,341,26,321,1847,1183,227,1916,2128,1509,2205,2996,673,528,2386,2903,1590,1595,2335,311,2644,2600,2267,3213,1525,546,312,2735,1608,2848,2228,1359,29,1740,1479,2353,1481,849,2355,2819,2093,400,13,3111,1750,857,2619,599,694,1423,1424,1685
|
0.5784922208777676,-0.24316559991811548,-1.5644818109642689,0.5784922208777676,0.19054865591249434,0.019486354875994212,2.2705322165054698,0.713579835070738,-0.0672262509964336,0.048211934796472365,1.031106974534266,-0.6668117578076647,0.19054865591249434,0.13386805297961285,-0.7598800080904538,-0.7287703736920425,1.1608155122181425,0.5512660173470204,-0.15476681385717422,1.6412063989989234,0.21876491453847344,1.983768672818817,0.5239685462529114,0.16225002844017103,0.952569994453112,3.164753514554234,1.004988400356168,-0.1254926486793712,0.19054865591249434,1.2379520800421246,-0.15476681385717422,-0.24316559991811548,0.019486354875994212,-0.2728238448155597,-0.82235748271142,0.5512660173470204,0.713579835070738,-0.36236611826561227,-0.7287703736920425,-0.009327790283860563,-0.009327790283860563,-0.33242471265450957,1.031106974534266,-0.5134593662434148,-0.4830577925150717,-0.3025770869123972,-1.3668267524146023,0.019486354875994212,0.6866990592950521,1.031106974534266,-0.5745330198140897,-0.009327790283860563,-0.6668117578076647,-0.2728238448155597,0.10540172980990664,3.1201613747468726,-0.0672262509964336,0.048211934796472365,-0.33242471265450957,0.048211934796472365,0.41405059073486755,-0.33242471265450957,-0.6359637761900813,-0.21360297580762733,0.873480632258922,3.9895804689666323,-1.0118216311731156,-0.0672262509964336,0.41405059073486755,-0.4830577925150717,0.6327337919013768,0.5512660173470204,0.07685003800728503,0.07685003800728503,-0.038231613171792155
| 3,375
|
metalloprotease
| 13
| 27
| 2.436839
| 0.014816
|
P31930,Q5JRX3,Q9NQH7,O75844,P55786,O95630,Q9Y4W6,Q9NZ08,Q8IYS1,O43847,Q7Z2K6,P14735,Q9BYT8
|
Functions
|
Panther Protein class
|
panther_protein_class
|
539,296,263,471,7,317,578,103,439,386,638,519,57
|
386,947,471,317,3236,1565,519,2539,3143,539,1912,2256,7,999,296,676,638,439,2225,2464,1356,57,263,1158,103,1826,578
|
0.873480632258922,0.33082515613705404,0.7671410746721091,1.004988400356168,-1.5313475075418816,-0.009327790283860563,0.713579835070738,-0.45274711809482365,-1.1076741576662066,0.6866990592950521,-0.15476681385717422,-0.3025770869123972,4.918525847007338,0.30292897251860446,1.057165873125376,0.5512660173470204,0.5784922208777676,0.8204396326290617,-0.2728238448155597,-0.39240070950050854,0.10540172980990664,2.4584637978137454,1.1349899370587961,0.21876491453847344,1.983768672818817,-0.09631286647900751,0.6597506092154378
| 3,375
|
Exercise intolerance
| 9
| 37
| 2.428182
| 0.015175
|
Q96RR1,P23786,P46020,P13807,Q8NFF5,P12235,Q9H2D1,Q8NI60,P03886
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
219,34,192,167,272,143,29,93,31
|
1896,494,2244,31,2487,1561,143,167,34,1636,953,1219,2493,2122,192,1572,1575,2758,671,3118,3205,768,272,93,2076,219,1408,2280,29,819,1361,2235,2982,363,3172,2851,2102
|
-0.15476681385717422,0.7403936172598823,-0.3025770869123972,3.030593559630485,-0.42252790140681873,-0.009327790283860563,1.6412063989989234,1.491534732272122,2.985614892363513,-0.038231613171792155,0.33082515613705404,0.16225002844017103,-0.42252790140681873,-0.24316559991811548,1.3654085471612543,-0.009327790283860563,-0.009327790283860563,-0.6052040240979027,0.5512660173470204,-1.04369050099163,-1.334155331699041,0.4691567512932392,1.1091068208502726,2.0560289253619395,-0.21360297580762733,1.2635525405656844,0.07685003800728503,-0.3025770869123972,3.1201613747468726,0.44164086630862914,0.10540172980990664,-0.2728238448155597,-0.7910758719515134,0.9262690243148245,-1.1719828815512887,-0.6668117578076647,-0.21360297580762733
| 3,375
|
Organic acid transmembrane transporter activity
| 6
| 23
| 2.424653
| 0.015323
|
P53007,P41440,O95563,P08195,P30825,Q9H2D1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
227,321,302,252,26,29
|
2104,628,1693,302,2894,252,26,321,227,1916,2205,1595,2267,2735,2848,29,1740,1479,2353,400,1750,2619,1423
|
-0.24316559991811548,0.5784922208777676,-0.0672262509964336,1.031106974534266,-0.7287703736920425,1.1608155122181425,3.164753514554234,1.004988400356168,1.2379520800421246,-0.15476681385717422,-0.2728238448155597,-0.009327790283860563,-0.3025770869123972,-0.5745330198140897,-0.6668117578076647,3.1201613747468726,-0.0672262509964336,0.048211934796472365,-0.33242471265450957,0.873480632258922,-0.0672262509964336,-0.4830577925150717,0.07685003800728503
| 3,375
|
Valine leucine and isoleucine degradation
| 7
| 32
| 2.420398
| 0.015504
|
P11310,P35610,Q16836,P30084,Q9HCC0,Q9BWD1,P30837
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
1,407,15,204,420,88,55
|
3059,726,2113,602,1771,1326,2363,1,1635,1842,2368,1446,204,55,1273,407,1569,2122,1571,1040,2047,3307,410,2758,2866,2960,15,1866,2082,2974,88,420
|
-0.948331973940958,0.49659904864423754,-0.24316559991811548,0.6056479018936,-0.09631286647900751,0.10540172980990664,-0.36236611826561227,7.367385577094042,-0.038231613171792155,-0.1254926486793712,-0.36236611826561227,0.048211934796472365,1.3145887721057432,2.4584637978137454,0.13386805297961285,0.8469920138668321,-0.009327790283860563,-0.24316559991811548,-0.009327790283860563,0.27495414250230754,-0.21360297580762733,-2.036174700270587,0.8469920138668321,-0.6052040240979027,-0.6977474581428348,-0.7910758719515134,3.797869337859779,-0.1254926486793712,-0.21360297580762733,-0.7910758719515134,2.1039880520769403,0.8469920138668321
| 3,375
|
Cysteine type endopeptidase activity
| 11
| 20
| 2.420328
| 0.015507
|
P07384,P51784,Q86UV5,Q9P0U3,Q99538,P42574,Q13867,Q93009,Q9Y4E8,Q96RU2,Q96K76
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
68,322,396,576,137,729,46,443,425,620,63
|
68,3201,910,729,2429,322,1849,46,1516,396,1473,778,443,63,620,137,576,2410,425,2170
|
2.294161378716793,-1.334155331699041,0.358643578170959,0.49659904864423754,-0.39240070950050854,1.004988400356168,-0.1254926486793712,2.666980836977603,0.019486354875994212,0.873480632258922,0.048211934796472365,0.4691567512932392,0.8204396326290617,2.3648106652398435,0.6056479018936,1.6907038084850876,0.6597506092154378,-0.36236611826561227,0.8469920138668321,-0.24316559991811548
| 3,375
|
Muscle spasm
| 10
| 63
| 2.415438
| 0.015716
|
P11310,P23786,Q96RR1,P35637,P00846,Q68CQ7,P12235,Q92804,O95140,Q99497
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,34,219,320,260,170,143,144,331,20
|
1028,3231,2240,3097,1763,331,2787,1896,2244,260,1962,2179,3269,1324,1770,991,1561,1326,902,1,143,34,953,320,2122,1705,956,2756,916,1572,1916,1575,1576,1786,2758,1650,1087,735,2867,1853,1286,2596,705,170,2908,2395,2731,2147,144,1606,219,20,2348,2280,1677,2703,380,689,852,1752,2851,2620,2823
|
0.27495414250230754,-1.4653079613874214,-0.3025770869123972,-1.0118216311731156,-0.09631286647900751,0.978809595175081,-0.6359637761900813,-0.15476681385717422,-0.3025770869123972,1.1349899370587961,-0.18413660636999382,-0.2728238448155597,-1.7312845351077755,0.10540172980990664,-0.09631286647900751,0.30292897251860446,-0.009327790283860563,0.10540172980990664,0.358643578170959,7.367385577094042,1.6412063989989234,2.985614892363513,0.33082515613705404,1.004988400356168,-0.24316559991811548,-0.0672262509964336,0.33082515613705404,-0.6052040240979027,0.358643578170959,-0.009327790283860563,-0.15476681385717422,-0.009327790283860563,-0.009327790283860563,-0.09631286647900751,-0.6052040240979027,-0.038231613171792155,0.24689976348114367,0.49659904864423754,-0.6977474581428348,-0.1254926486793712,0.13386805297961285,-0.4830577925150717,0.5239685462529114,1.491534732272122,-0.7287703736920425,-0.36236611826561227,-0.5745330198140897,-0.24316559991811548,1.6412063989989234,-0.009327790283860563,1.2635525405656844,3.582293433383776,-0.33242471265450957,-0.3025770869123972,-0.038231613171792155,-0.5439512892731678,0.8999061013249092,0.5512660173470204,0.41405059073486755,-0.0672262509964336,-0.6668117578076647,-0.4830577925150717,-0.6359637761900813
| 3,375
|
Alzheimers disease and mirna effects
| 16
| 88
| 2.411985
| 0.015866
|
P49841,Q12933,Q13885,P07384,Q96BY7,Q9NQC3,O95197,P49721,Q96GC9,P60900,Q9Y4P8,P12235,P07437,P68371,P28074,P31751
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
32,96,161,68,298,230,259,40,136,344,251,143,264,346,238,154
|
2019,2621,1835,1369,2479,1551,259,2712,2713,1174,2300,68,264,1495,143,1122,519,1037,3201,1700,1386,1498,907,803,700,2424,829,1270,1905,2189,2790,556,472,238,2309,2674,154,863,1179,2753,1500,1846,729,1783,1847,2372,995,1041,2680,40,32,2432,2795,344,2759,2204,1790,998,346,1047,872,1511,1049,1188,96,1000,836,161,1800,2445,2873,775,2345,298,136,2884,464,2277,1940,2974,934,935,360,230,2470,1952,857,251
|
-0.21360297580762733,-0.5134593662434148,-0.1254926486793712,0.07685003800728503,-0.42252790140681873,-0.009327790283860563,1.1349899370587961,-0.5745330198140897,-0.5745330198140897,0.19054865591249434,-0.33242471265450957,2.294161378716793,1.1091068208502726,0.019486354875994212,1.6412063989989234,0.21876491453847344,0.713579835070738,0.27495414250230754,-1.334155331699041,-0.0672262509964336,0.07685003800728503,0.019486354875994212,0.358643578170959,0.44164086630862914,0.5239685462529114,-0.39240070950050854,0.41405059073486755,0.13386805297961285,-0.15476681385717422,-0.2728238448155597,-0.6359637761900813,0.6597506092154378,0.7671410746721091,1.1865840591524877,-0.33242471265450957,-0.5439512892731678,1.5665946676492313,0.38638510613707605,0.19054865591249434,-0.6052040240979027,0.019486354875994212,-0.1254926486793712,0.49659904864423754,-0.09631286647900751,-0.1254926486793712,-0.36236611826561227,0.30292897251860446,0.27495414250230754,-0.5439512892731678,2.7358317422764893,3.030593559630485,-0.39240070950050854,-0.6359637761900813,0.952569994453112,-0.6052040240979027,-0.2728238448155597,-0.09631286647900751,0.30292897251860446,0.952569994453112,0.27495414250230754,0.38638510613707605,0.019486354875994212,0.27495414250230754,0.19054865591249434,2.031985358818018,0.30292897251860446,0.41405059073486755,1.5416250265376559,-0.09631286647900751,-0.39240070950050854,-0.6977474581428348,0.4691567512932392,-0.33242471265450957,1.057165873125376,1.6907038084850876,-0.6977474581428348,0.7938228645047847,-0.3025770869123972,-0.15476681385717422,-0.7910758719515134,0.358643578170959,0.358643578170959,0.9262690243148245,1.2379520800421246,-0.39240070950050854,-0.15476681385717422,0.41405059073486755,1.1865840591524877
| 3,375
|
Cellular modified amino acid metabolic process
| 14
| 59
| 2.409718
| 0.015965
|
P11310,O00469,P23786,P41440,Q9NVH6,Q8IYS1,Q9UHG3,Q8WUX2,Q99497,P50416,P48507,Q9UKG9,Q9H2D1,O75874
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,280,34,321,91,439,13,441,20,266,342,160,29,95
|
625,280,1168,859,3162,95,1436,1438,450,2485,3237,1493,1,1120,1965,904,3041,1385,994,2789,1079,34,2119,557,953,2039,2955,1331,321,1848,342,2634,2200,2047,3307,1336,266,1647,1651,2216,439,1053,2070,3279,1667,441,2074,20,2699,3357,3261,29,572,785,91,13,160,1829,2917
|
0.5784922208777676,1.0831656426328216,0.19054865591249434,0.38638510613707605,-1.1719828815512887,2.031985358818018,0.048211934796472365,0.048211934796472365,0.7938228645047847,-0.42252790140681873,-1.5313475075418816,0.019486354875994212,7.367385577094042,0.21876491453847344,-0.18413660636999382,0.358643578170959,-0.9167120699523604,0.07685003800728503,0.30292897251860446,-0.6359637761900813,0.24689976348114367,2.985614892363513,-0.24316559991811548,0.6597506092154378,0.33082515613705404,-0.21360297580762733,-0.7910758719515134,0.10540172980990664,1.004988400356168,-0.1254926486793712,0.952569994453112,-0.5134593662434148,-0.2728238448155597,-0.21360297580762733,-2.036174700270587,0.10540172980990664,1.1091068208502726,-0.038231613171792155,-0.038231613171792155,-0.2728238448155597,0.8204396326290617,0.27495414250230754,-0.21360297580762733,-1.7985271289035507,-0.038231613171792155,0.8204396326290617,-0.21360297580762733,3.582293433383776,-0.5439512892731678,-3.311486278244562,-1.6643385894420446,3.1201613747468726,0.6597506092154378,0.4691567512932392,2.0800297213070706,3.9895804689666323,1.5665946676492313,-0.09631286647900751,-0.7287703736920425
| 3,375
|
Ion transport
| 65
| 219
| 2.40839
| 0.016023
|
Q9UBX3,Q13546,Q13423,P00846,O15439,Q9HC07,O75351,O00299,Q96GC9,Q9UHG3,P12235,O60831,P61201,Q9UDW1,Q6P4A7,Q99497,Q9HD20,Q6PML9,O14936,Q8N668,P30825,Q9H2D1,Q8WWC4,Q8TB61,P31930,O43772,Q9Y5P4,P46939,P61421,Q9Y4W6,P0CG08,Q6YHU6,Q9UI12,P42858,Q8TDW0,Q6KCM7,Q8NE01,Q13131,P28161,P17931,O95563,Q70HW3,Q9Y4C2,P07384,O43865,Q9BPX6,O75964,P41440,Q8N4V1,P30536,P24941,P54652,P53007,P46934,P14174,O75844,Q6P4Q7,Q13555,Q8IYU8,Q9NRA0,P00403,P20337,Q96HE7,P08195,O15173
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
400,528,262,260,628,139,629,625,136,13,143,514,637,687,269,20,151,270,383,285,26,29,286,546,539,33,694,540,293,578,662,413,447,175,312,311,440,673,557,305,302,188,599,68,69,465,698,321,81,341,367,476,227,473,101,471,357,355,502,109,494,119,650,252,489
|
858,625,722,897,2103,3096,2104,3242,383,489,628,1167,1626,33,1491,69,1556,514,946,2239,1690,629,947,1693,471,1436,3126,698,2110,2029,302,2670,1696,494,260,3236,2825,948,2179,2628,2713,1174,1263,1073,2580,68,2924,1964,2894,252,1265,662,1495,1564,1900,2032,1120,143,1122,2986,1633,101,1037,1634,2364,305,1841,1444,119,827,2716,1123,2247,700,1177,367,2037,2834,2190,557,1218,2674,341,1330,26,539,863,1179,3256,2718,1844,2542,1448,321,175,1847,2545,473,540,2371,3045,1222,1183,831,227,1916,476,1710,2128,1086,2681,637,293,3257,2257,2378,1647,2438,1509,1047,1793,1390,2205,2593,2261,1049,2996,2687,2132,673,262,528,355,1283,2386,2331,2903,1590,2870,3205,1595,2967,3365,2212,2335,311,2644,2600,2267,269,357,270,413,188,2142,3213,1525,2647,502,81,285,440,775,546,312,286,1238,1057,136,650,2735,1608,20,3137,3138,465,2848,3301,3288,2228,1359,3214,2280,29,1740,2351,1479,2353,139,1481,151,849,109,938,978,2355,2819,2093,400,687,791,13,3111,447,1750,1485,2941,2742,2097,2981,857,2619,2474,599,578,694,1423,1424,1685
|
0.38638510613707605,0.5784922208777676,0.49659904864423754,0.358643578170959,-0.24316559991811548,-1.0118216311731156,-0.24316559991811548,-1.5644818109642689,0.873480632258922,0.7403936172598823,0.5784922208777676,0.19054865591249434,-0.038231613171792155,3.0081206146023467,0.019486354875994212,2.2705322165054698,-0.009327790283860563,0.713579835070738,0.33082515613705404,-0.3025770869123972,-0.0672262509964336,0.5784922208777676,0.33082515613705404,-0.0672262509964336,0.7671410746721091,0.048211934796472365,-1.075641485634037,0.5239685462529114,-0.24316559991811548,-0.21360297580762733,1.031106974534266,-0.5439512892731678,-0.0672262509964336,0.7403936172598823,1.1349899370587961,-1.5313475075418816,-0.6668117578076647,0.33082515613705404,-0.2728238448155597,-0.5134593662434148,-0.5745330198140897,0.19054865591249434,0.13386805297961285,0.24689976348114367,-0.4830577925150717,2.294161378716793,-0.7598800080904538,-0.18413660636999382,-0.7287703736920425,1.1608155122181425,0.13386805297961285,0.5512660173470204,0.019486354875994212,-0.009327790283860563,-0.15476681385717422,-0.21360297580762733,0.21876491453847344,1.6412063989989234,0.21876491453847344,-0.82235748271142,-0.038231613171792155,1.983768672818817,0.27495414250230754,-0.038231613171792155,-0.36236611826561227,1.031106974534266,-0.1254926486793712,0.048211934796472365,1.8380591236082113,0.41405059073486755,-0.5745330198140897,0.21876491453847344,-0.3025770869123972,0.5239685462529114,0.19054865591249434,0.8999061013249092,-0.21360297580762733,-0.6668117578076647,-0.2728238448155597,0.6597506092154378,0.16225002844017103,-0.5439512892731678,0.952569994453112,0.10540172980990664,3.164753514554234,0.6866990592950521,0.38638510613707605,0.19054865591249434,-1.6643385894420446,-0.5745330198140897,-0.1254926486793712,-0.45274711809482365,0.048211934796472365,1.004988400356168,1.4664132535336514,-0.1254926486793712,-0.45274711809482365,0.7671410746721091,0.6866990592950521,-0.36236611826561227,-0.9167120699523604,0.16225002844017103,0.19054865591249434,0.41405059073486755,1.2379520800421246,-0.15476681385717422,0.7671410746721091,-0.0672262509964336,-0.24316559991811548,0.24689976348114367,-0.5439512892731678,0.5784922208777676,1.057165873125376,-1.6643385894420446,-0.3025770869123972,-0.36236611826561227,-0.038231613171792155,-0.39240070950050854,0.019486354875994212,0.27495414250230754,-0.09631286647900751,0.07685003800728503,-0.2728238448155597,-0.4830577925150717,-0.3025770869123972,0.27495414250230754,-0.82235748271142,-0.5439512892731678,-0.24316559991811548,0.5512660173470204,1.1349899370587961,0.713579835070738,0.9262690243148245,0.13386805297961285,-0.36236611826561227,-0.33242471265450957,-0.7287703736920425,-0.009327790283860563,-0.6977474581428348,-1.334155331699041,-0.009327790283860563,-0.7910758719515134,-4.017752483133644,-0.2728238448155597,-0.33242471265450957,1.031106974534266,-0.5134593662434148,-0.4830577925150717,-0.3025770869123972,1.1091068208502726,0.9262690243148245,1.1091068208502726,0.8469920138668321,1.39073841091754,-0.24316559991811548,-1.3668267524146023,0.019486354875994212,-0.5134593662434148,0.7403936172598823,2.1517785208460363,1.0831656426328216,0.8204396326290617,0.4691567512932392,0.6866990592950521,1.031106974534266,1.0831656426328216,0.16225002844017103,0.27495414250230754,1.6907038084850876,0.5784922208777676,-0.5745330198140897,-0.009327790283860563,3.582293433383776,-1.075641485634037,-1.075641485634037,0.7938228645047847,-0.6668117578076647,-1.9338917553280288,-1.8660637299899208,-0.2728238448155597,0.10540172980990664,-1.3668267524146023,-0.3025770869123972,3.1201613747468726,-0.0672262509964336,-0.33242471265450957,0.048211934796472365,-0.33242471265450957,1.6907038084850876,0.048211934796472365,1.6163849582577512,0.41405059073486755,1.935377141239234,0.358643578170959,0.33082515613705404,-0.33242471265450957,-0.6359637761900813,-0.21360297580762733,0.873480632258922,0.5512660173470204,0.4691567512932392,3.9895804689666323,-1.0118216311731156,0.8204396326290617,-0.0672262509964336,0.048211934796472365,-0.7598800080904538,-0.5745330198140897,-0.21360297580762733,-0.7910758719515134,0.41405059073486755,-0.4830577925150717,-0.39240070950050854,0.6327337919013768,0.6597506092154378,0.5512660173470204,0.07685003800728503,0.07685003800728503,-0.038231613171792155
| 3,375
|
Lysine degradation
| 7
| 24
| 2.404956
| 0.016174
|
O00469,P35610,Q16836,P30084,Q9BWD1,P30837,Q9NVH6
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
280,407,15,204,88,55,91
|
280,987,859,1895,726,2368,204,55,407,2427,2122,2047,3307,410,1649,1455,1658,15,1934,2076,88,785,91,1106
|
1.0831656426328216,0.30292897251860446,0.38638510613707605,-0.15476681385717422,0.49659904864423754,-0.36236611826561227,1.3145887721057432,2.4584637978137454,0.8469920138668321,-0.39240070950050854,-0.24316559991811548,-0.21360297580762733,-2.036174700270587,0.8469920138668321,-0.038231613171792155,0.048211934796472365,-0.038231613171792155,3.797869337859779,-0.15476681385717422,-0.21360297580762733,2.1039880520769403,0.4691567512932392,2.0800297213070706,0.24689976348114367
| 3,375
|
Protein localization to extracellular region
| 24
| 67
| 2.402531
| 0.016282
|
Q12846,Q16836,P49755,O43768,Q99497,P50416,P04035,Q96KC8,P51153,O95563,Q9UBV2,Q32P28,Q9Y678,Q9UBF2,Q96PC5,Q86YV9,Q9NV70,Q9HCU5,Q16850,Q9H4A6,Q6IQ22,Q13555,P20337,Q9BRT2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
527,15,636,513,20,266,661,569,668,302,198,65,468,719,463,460,594,336,82,622,478,355,119,651
|
2171,2621,697,897,3022,513,2108,2535,302,1262,661,2825,1561,2033,2304,1077,119,2034,908,1272,1780,1330,2195,2122,1707,636,266,668,3303,1916,2128,3012,2797,1184,2056,1049,1188,527,355,2870,1051,15,82,65,1004,478,1052,2339,879,2602,460,2563,2769,775,2511,569,463,1606,20,651,622,336,594,719,198,1254,468
|
-0.2728238448155597,-0.5134593662434148,0.5239685462529114,0.358643578170959,-0.8851760478860837,0.713579835070738,-0.24316559991811548,-0.45274711809482365,1.031106974534266,0.13386805297961285,0.5512660173470204,-0.6668117578076647,-0.009327790283860563,-0.21360297580762733,-0.33242471265450957,0.24689976348114367,1.8380591236082113,-0.21360297580762733,0.358643578170959,0.13386805297961285,-0.09631286647900751,0.10540172980990664,-0.2728238448155597,-0.24316559991811548,-0.0672262509964336,0.5784922208777676,1.1091068208502726,0.5512660173470204,-1.96791426020348,-0.15476681385717422,-0.24316559991811548,-0.8537243644783261,-0.6359637761900813,0.19054865591249434,-0.21360297580762733,0.27495414250230754,0.19054865591249434,0.713579835070738,0.9262690243148245,-0.6977474581428348,0.27495414250230754,3.797869337859779,2.1279042192938276,2.341300334418682,0.30292897251860446,0.7671410746721091,0.27495414250230754,-0.33242471265450957,0.38638510613707605,-0.4830577925150717,0.7938228645047847,-0.45274711809482365,-0.6052040240979027,0.4691567512932392,-0.42252790140681873,0.6597506092154378,0.7938228645047847,-0.009327790283860563,3.582293433383776,0.5784922208777676,0.6056479018936,0.978809595175081,0.6327337919013768,0.5239685462529114,1.3654085471612543,0.16225002844017103,0.7938228645047847
| 3,375
|
Metabolism of water soluble vitamins and cofactors
| 8
| 41
| 2.388981
| 0.016895
|
P41440,Q9BQG2,P43490,Q8NFF5,Q96EY8,Q4G0N4,Q9NVE7,Q9H2D1
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
321,274,14,272,48,23,289,29
|
1687,1429,898,2950,631,1438,725,2113,602,1900,2115,1965,1385,1842,2955,1331,321,14,1041,1336,1647,2442,1716,23,2216,2878,272,2001,48,2082,570,274,29,1481,420,1681,785,289,2619,2917,3078
|
-0.0672262509964336,0.048211934796472365,0.358643578170959,-0.7910758719515134,0.5784922208777676,0.048211934796472365,0.49659904864423754,-0.24316559991811548,0.6056479018936,-0.15476681385717422,-0.24316559991811548,-0.18413660636999382,0.07685003800728503,-0.1254926486793712,-0.7910758719515134,0.10540172980990664,1.004988400356168,3.797869337859779,0.27495414250230754,0.10540172980990664,-0.038231613171792155,-0.39240070950050854,-0.0672262509964336,3.4077973078556516,-0.2728238448155597,-0.6977474581428348,1.1091068208502726,-0.18413660636999382,2.6439590132330637,-0.21360297580762733,0.6597506092154378,1.1091068208502726,3.1201613747468726,0.048211934796472365,0.8469920138668321,-0.038231613171792155,0.4691567512932392,1.0831656426328216,-0.4830577925150717,-0.7287703736920425,-0.948331973940958
| 3,375
|
protein modifying enzyme
| 7
| 28
| 2.384101
| 0.017121
|
Q9H488,O15460,P13674,O75718,Q15418,Q92791,P51812
|
Functions
|
Panther Protein class
|
panther_protein_class
|
121,74,76,78,53,56,239
|
280,2238,1372,74,859,751,3162,78,76,3219,2864,239,1581,1455,1797,1591,53,2907,2394,964,459,882,56,1205,121,2778,1546,2523
|
1.0831656426328216,-0.3025770869123972,0.07685003800728503,2.223153155757611,0.38638510613707605,0.4691567512932392,-1.1719828815512887,2.199402700232554,2.223153155757611,-1.3995762482720377,-0.6977474581428348,1.1865840591524877,-0.009327790283860563,0.048211934796472365,-0.09631286647900751,-0.009327790283860563,2.4817813149505383,-0.7287703736920425,-0.36236611826561227,0.33082515613705404,0.7938228645047847,0.38638510613707605,2.4584637978137454,0.19054865591249434,1.8380591236082113,-0.6052040240979027,0.019486354875994212,-0.42252790140681873
| 3,375
|
Negative regulation of cysteine type endopeptidase activity
| 7
| 21
| 2.382072
| 0.017216
|
Q9NWS0,Q15392,Q99497,Q15418,P51812,Q9Y3B8,Q96K76
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
328,12,20,53,239,424,63
|
1428,3308,659,1699,994,405,2954,1909,239,637,1453,2764,2903,12,53,1861,63,20,1822,328,424
|
0.048211934796472365,-2.0704120237229517,0.5512660173470204,-0.0672262509964336,0.30292897251860446,0.8469920138668321,-0.7910758719515134,-0.15476681385717422,1.1865840591524877,0.5784922208777676,0.048211934796472365,-0.6052040240979027,-0.7287703736920425,4.031896411144352,2.4817813149505383,-0.1254926486793712,2.3648106652398435,3.582293433383776,-0.09631286647900751,1.004988400356168,0.8469920138668321
| 3,375
|
Cation transmembrane transport
| 31
| 127
| 2.380305
| 0.017298
|
Q13423,P00846,Q9HC07,Q96GC9,P12235,Q6PML9,Q99497,Q9HD20,Q8N668,P30825,Q8WWC4,P31930,O43772,P46939,P61421,Q9Y4W6,Q6YHU6,Q9UI12,P42858,Q6KCM7,Q70HW3,P07384,Q9BPX6,Q8N4V1,P54652,P46934,Q6P4Q7,Q8IYU8,Q9NRA0,P00403,P08195
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
262,260,139,136,143,270,20,151,285,26,286,539,33,540,293,578,413,447,175,311,188,68,465,81,476,473,357,502,109,494,252
|
722,2103,3096,2104,1626,33,1556,946,1690,947,3126,698,2029,2670,494,260,2179,2628,2713,1174,1263,1073,2580,68,1964,252,1265,1495,1564,1120,143,2986,1037,1634,2364,1841,1444,827,2716,1123,2247,700,1177,2037,2834,2190,557,2674,1330,26,539,3256,2718,1844,2542,1448,175,473,540,2371,3045,1222,476,1710,2128,1086,2681,293,2257,2378,1647,2438,1509,1047,2593,2261,2687,2132,262,1283,2870,3205,1595,2335,311,357,270,413,188,2142,2647,502,81,285,775,286,1057,136,650,2735,20,3137,3138,465,3301,3214,2280,1740,2351,1479,2353,139,1481,151,109,938,978,2355,687,791,447,1485,2742,2474,578,1423,1685
|
0.49659904864423754,-0.24316559991811548,-1.0118216311731156,-0.24316559991811548,-0.038231613171792155,3.0081206146023467,-0.009327790283860563,0.33082515613705404,-0.0672262509964336,0.33082515613705404,-1.075641485634037,0.5239685462529114,-0.21360297580762733,-0.5439512892731678,0.7403936172598823,1.1349899370587961,-0.2728238448155597,-0.5134593662434148,-0.5745330198140897,0.19054865591249434,0.13386805297961285,0.24689976348114367,-0.4830577925150717,2.294161378716793,-0.18413660636999382,1.1608155122181425,0.13386805297961285,0.019486354875994212,-0.009327790283860563,0.21876491453847344,1.6412063989989234,-0.82235748271142,0.27495414250230754,-0.038231613171792155,-0.36236611826561227,-0.1254926486793712,0.048211934796472365,0.41405059073486755,-0.5745330198140897,0.21876491453847344,-0.3025770869123972,0.5239685462529114,0.19054865591249434,-0.21360297580762733,-0.6668117578076647,-0.2728238448155597,0.6597506092154378,-0.5439512892731678,0.10540172980990664,3.164753514554234,0.6866990592950521,-1.6643385894420446,-0.5745330198140897,-0.1254926486793712,-0.45274711809482365,0.048211934796472365,1.4664132535336514,0.7671410746721091,0.6866990592950521,-0.36236611826561227,-0.9167120699523604,0.16225002844017103,0.7671410746721091,-0.0672262509964336,-0.24316559991811548,0.24689976348114367,-0.5439512892731678,1.057165873125376,-0.3025770869123972,-0.36236611826561227,-0.038231613171792155,-0.39240070950050854,0.019486354875994212,0.27495414250230754,-0.4830577925150717,-0.3025770869123972,-0.5439512892731678,-0.24316559991811548,1.1349899370587961,0.13386805297961285,-0.6977474581428348,-1.334155331699041,-0.009327790283860563,-0.33242471265450957,1.031106974534266,0.9262690243148245,1.1091068208502726,0.8469920138668321,1.39073841091754,-0.24316559991811548,-0.5134593662434148,0.7403936172598823,2.1517785208460363,1.0831656426328216,0.4691567512932392,1.0831656426328216,0.27495414250230754,1.6907038084850876,0.5784922208777676,-0.5745330198140897,3.582293433383776,-1.075641485634037,-1.075641485634037,0.7938228645047847,-1.9338917553280288,-1.3668267524146023,-0.3025770869123972,-0.0672262509964336,-0.33242471265450957,0.048211934796472365,-0.33242471265450957,1.6907038084850876,0.048211934796472365,1.6163849582577512,1.935377141239234,0.358643578170959,0.33082515613705404,-0.33242471265450957,0.5512660173470204,0.4691567512932392,0.8204396326290617,0.048211934796472365,-0.5745330198140897,-0.39240070950050854,0.6597506092154378,0.07685003800728503,-0.038231613171792155
| 3,375
|
Regulation of carbohydrate metabolic process
| 9
| 37
| 2.377734
| 0.017419
|
Q9UNI6,P11310,P49841,Q92520,Q93009,Q9BYT8,Q15120,P31751,Q9Y6N1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
402,1,32,172,443,57,90,154,427
|
1367,1687,1372,2531,1693,471,1694,1322,2713,1,2715,907,154,2369,3211,1130,805,32,2127,1787,997,2836,2377,1793,2899,673,3195,3104,90,1135,172,443,1202,57,2007,402,427
|
0.07685003800728503,-0.0672262509964336,0.07685003800728503,-0.45274711809482365,-0.0672262509964336,0.7671410746721091,-0.0672262509964336,0.10540172980990664,-0.5745330198140897,7.367385577094042,-0.5745330198140897,0.358643578170959,1.5665946676492313,-0.36236611826561227,-1.3668267524146023,0.21876491453847344,0.44164086630862914,3.030593559630485,-0.24316559991811548,-0.09631286647900751,0.30292897251860446,-0.6668117578076647,-0.36236611826561227,-0.09631286647900751,-0.7287703736920425,0.5512660173470204,-1.3015623678515262,-1.0118216311731156,2.0800297213070706,0.21876491453847344,1.491534732272122,0.8204396326290617,0.19054865591249434,2.4584637978137454,-0.18413660636999382,0.873480632258922,0.8469920138668321
| 3,375
|
Selective autophagy
| 12
| 32
| 2.373471
| 0.017622
|
Q13885,Q15388,P21796,P50542,O95140,P08670,Q8N4H5,Q99497,P68371,Q9NS69,Q9Y6G9,P63167
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
161,37,700,606,331,451,644,20,346,27,695,323
|
988,750,1891,331,1696,2030,451,2182,1498,700,606,2127,1786,2683,323,998,346,1983,1853,161,1655,37,1932,644,2909,2462,2883,20,934,935,27,695
|
0.30292897251860446,0.4691567512932392,-0.15476681385717422,0.978809595175081,-0.0672262509964336,-0.21360297580762733,0.7938228645047847,-0.2728238448155597,0.019486354875994212,0.5239685462529114,0.6056479018936,-0.24316559991811548,-0.09631286647900751,-0.5439512892731678,1.004988400356168,0.30292897251860446,0.952569994453112,-0.18413660636999382,-0.1254926486793712,1.5416250265376559,-0.038231613171792155,2.84988124164933,-0.15476681385717422,0.5784922208777676,-0.7287703736920425,-0.39240070950050854,-0.6977474581428348,3.582293433383776,0.358643578170959,0.358643578170959,3.1424732722153843,0.5512660173470204
| 3,375
|
Retinal vascular tortuosity
| 8
| 15
| 2.348118
| 0.018869
|
O00192,P00846,Q15056,Q9C0D9,Q92766,O75306,Q92890,P03886
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
537,260,233,106,442,581,150,31
|
537,581,260,31,1078,2676,608,2637,233,442,150,2149,106,1881,1253
|
0.6866990592950521,0.6327337919013768,1.1349899370587961,3.030593559630485,0.24689976348114367,-0.5439512892731678,0.6056479018936,-0.5134593662434148,1.212296082730813,0.8204396326290617,1.6163849582577512,-0.24316559991811548,1.9595949228824863,-0.1254926486793712,0.16225002844017103
| 3,375
|
Congenital contracture
| 8
| 43
| 2.340342
| 0.019266
|
P11310,Q04446,P53007,Q969X5,Q96S52,Q15392,Q8NCH0,Q96AY3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,261,227,135,273,12,185,124
|
697,280,1028,471,3079,1962,2487,1,3080,1776,3211,1222,227,1047,261,1087,1049,1652,2725,1517,12,1593,3258,677,1527,185,1054,967,135,2346,618,124,273,1736,2514,1058,592,2091,655,1065,2098,2620,2823
|
0.5239685462529114,1.0831656426328216,0.27495414250230754,0.7671410746721091,-0.980035309228183,-0.18413660636999382,-0.42252790140681873,7.367385577094042,-0.980035309228183,-0.09631286647900751,-1.3668267524146023,0.16225002844017103,1.2379520800421246,0.27495414250230754,1.1349899370587961,0.24689976348114367,0.27495414250230754,-0.038231613171792155,-0.5745330198140897,0.019486354875994212,4.031896411144352,-0.009327790283860563,-1.6643385894420446,0.5512660173470204,0.019486354875994212,1.416015523904057,0.27495414250230754,0.33082515613705404,1.7153805361397676,-0.33242471265450957,0.6056479018936,1.8136162149972994,1.1091068208502726,-0.0672262509964336,-0.42252790140681873,0.27495414250230754,0.6327337919013768,-0.21360297580762733,0.5784922208777676,0.27495414250230754,-0.21360297580762733,-0.4830577925150717,-0.6359637761900813
| 3,375
|
Ion transmembrane transporter activity
| 32
| 108
| 2.339924
| 0.019288
|
Q9UBX3,Q13423,P00846,O15439,Q9HC07,O00299,P12235,Q6PML9,Q9UDW1,Q6P4A7,Q9HD20,P30825,Q9H2D1,Q8TB61,P31930,O43772,P61421,P0CG08,Q9UI12,Q8TDW0,Q6KCM7,O95563,Q70HW3,O75964,P41440,Q8N4V1,Q93050,P53007,Q6P4Q7,Q9Y487,P00403,P08195
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
400,262,260,628,139,625,143,270,687,269,151,26,29,546,539,33,293,662,447,312,311,302,188,698,321,81,616,227,357,250,494,252
|
625,3096,2104,628,1167,33,1491,1693,3126,698,2029,302,494,260,2179,2628,1174,1073,2580,1964,252,1265,662,1564,1900,143,1122,2986,1037,1444,827,2716,1123,700,1177,2037,26,539,3256,1844,2542,1448,321,1847,2371,3045,1183,227,1916,2128,1086,2681,293,2257,2438,1509,1047,2205,262,2386,2331,3205,1595,2335,311,2644,2600,2267,269,357,270,188,2142,1525,81,775,546,312,1238,1057,616,2735,1608,2848,3288,2228,3214,29,1740,1479,2353,139,1481,151,978,2355,400,687,447,1750,2742,857,2619,250,2017,1423,1424,1685
|
0.5784922208777676,-1.0118216311731156,-0.24316559991811548,0.5784922208777676,0.19054865591249434,3.0081206146023467,0.019486354875994212,-0.0672262509964336,-1.075641485634037,0.5239685462529114,-0.21360297580762733,1.031106974534266,0.7403936172598823,1.1349899370587961,-0.2728238448155597,-0.5134593662434148,0.19054865591249434,0.24689976348114367,-0.4830577925150717,-0.18413660636999382,1.1608155122181425,0.13386805297961285,0.5512660173470204,-0.009327790283860563,-0.15476681385717422,1.6412063989989234,0.21876491453847344,-0.82235748271142,0.27495414250230754,0.048211934796472365,0.41405059073486755,-0.5745330198140897,0.21876491453847344,0.5239685462529114,0.19054865591249434,-0.21360297580762733,3.164753514554234,0.6866990592950521,-1.6643385894420446,-0.1254926486793712,-0.45274711809482365,0.048211934796472365,1.004988400356168,-0.1254926486793712,-0.36236611826561227,-0.9167120699523604,0.19054865591249434,1.2379520800421246,-0.15476681385717422,-0.24316559991811548,0.24689976348114367,-0.5439512892731678,1.057165873125376,-0.3025770869123972,-0.39240070950050854,0.019486354875994212,0.27495414250230754,-0.2728238448155597,1.1349899370587961,-0.36236611826561227,-0.33242471265450957,-1.334155331699041,-0.009327790283860563,-0.33242471265450957,1.031106974534266,-0.5134593662434148,-0.4830577925150717,-0.3025770869123972,1.1091068208502726,0.9262690243148245,1.1091068208502726,1.39073841091754,-0.24316559991811548,0.019486354875994212,2.1517785208460363,0.4691567512932392,0.6866990592950521,1.031106974534266,0.16225002844017103,0.27495414250230754,0.6056479018936,-0.5745330198140897,-0.009327790283860563,-0.6668117578076647,-1.8660637299899208,-0.2728238448155597,-1.3668267524146023,3.1201613747468726,-0.0672262509964336,0.048211934796472365,-0.33242471265450957,1.6907038084850876,0.048211934796472365,1.6163849582577512,0.33082515613705404,-0.33242471265450957,0.873480632258922,0.5512660173470204,0.8204396326290617,-0.0672262509964336,-0.5745330198140897,0.41405059073486755,-0.4830577925150717,1.1865840591524877,-0.18413660636999382,0.07685003800728503,0.07685003800728503,-0.038231613171792155
| 3,375
|
Organic hydroxy compound metabolic process
| 19
| 111
| 2.339826
| 0.019293
|
P48735,Q15392,Q99538,Q99497,Q9UKG1,P38435,Q8WTV0,P30837,Q9H2C2,P43304,O94788,Q9BY49,Q16850,Q9NX62,Q96PE3,O75874,Q15800,Q9Y4G8,Q9NRA0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
11,12,137,20,152,174,50,55,66,200,75,203,82,215,94,95,234,108,109
|
1367,1429,237,3242,627,490,1113,2529,2920,2711,1693,95,75,2298,1627,1896,1438,725,1839,661,1962,1322,2713,726,1118,1771,992,1120,1075,1840,3009,2830,994,663,1902,907,1078,908,2118,2489,1218,2492,55,2835,407,521,174,3371,1571,200,3100,11,2756,1784,2048,3282,410,1976,2495,454,2796,1712,3238,2498,432,2866,2898,999,673,3366,585,1719,356,1459,2505,1858,2690,12,1987,234,1051,82,3167,348,2846,647,50,1202,1355,94,1606,2347,20,137,2974,1941,1016,1301,203,66,2737,2007,109,215,2356,1747,3111,152,535,108,2620
|
0.07685003800728503,0.048211934796472365,1.1865840591524877,-1.5644818109642689,0.5784922208777676,0.7403936172598823,0.21876491453847344,-0.45274711809482365,-0.7598800080904538,-0.5745330198140897,-0.0672262509964336,2.031985358818018,2.223153155757611,-0.33242471265450957,-0.038231613171792155,-0.15476681385717422,0.048211934796472365,0.49659904864423754,-0.1254926486793712,0.5512660173470204,-0.18413660636999382,0.10540172980990664,-0.5745330198140897,0.49659904864423754,0.21876491453847344,-0.09631286647900751,0.30292897251860446,0.21876491453847344,0.24689976348114367,-0.1254926486793712,-0.8537243644783261,-0.6668117578076647,0.30292897251860446,0.5512660173470204,-0.15476681385717422,0.358643578170959,0.24689976348114367,0.358643578170959,-0.24316559991811548,-0.42252790140681873,0.16225002844017103,-0.42252790140681873,2.4584637978137454,-0.6668117578076647,0.8469920138668321,0.713579835070738,1.4664132535336514,-7.168005489173489,-0.009327790283860563,1.340025485497747,-1.0118216311731156,4.470238014994655,-0.6052040240979027,-0.09631286647900751,-0.21360297580762733,-1.8322588413061764,0.8469920138668321,-0.18413660636999382,-0.42252790140681873,0.7938228645047847,-0.6359637761900813,-0.0672262509964336,-1.5313475075418816,-0.42252790140681873,0.8204396326290617,-0.6977474581428348,-0.7287703736920425,0.30292897251860446,0.5512660173470204,-4.055519423800208,0.6327337919013768,-0.0672262509964336,0.9262690243148245,0.048211934796472365,-0.42252790140681873,-0.1254926486793712,-0.5439512892731678,4.031896411144352,-0.18413660636999382,1.212296082730813,0.27495414250230754,2.1279042192938276,-1.1719828815512887,0.952569994453112,-0.6668117578076647,0.5784922208777676,2.5978067214134675,0.19054865591249434,0.10540172980990664,2.0560289253619395,-0.009327790283860563,-0.33242471265450957,3.582293433383776,1.6907038084850876,-0.7910758719515134,-0.15476681385717422,0.30292897251860446,0.13386805297961285,1.340025485497747,2.341300334418682,-0.5745330198140897,-0.18413660636999382,1.935377141239234,1.2890979463364292,-0.33242471265450957,-0.0672262509964336,-1.0118216311731156,1.6163849582577512,0.713579835070738,1.9595949228824863,-0.4830577925150717
| 3,375
|
Delayed cranial suture closure
| 9
| 28
| 2.335765
| 0.019504
|
Q32P28,Q08J23,O95155,O75718,Q9Y487,Q93009,Q8NCH0,P51812,Q15813
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,41,42,78,250,443,185,239,435
|
1257,2297,3039,78,471,42,3079,994,2247,727,2542,1448,3174,1081,1911,2200,1975,239,1576,41,1230,435,65,185,443,1242,2743,250
|
0.13386805297961285,-0.33242471265450957,-0.9167120699523604,2.199402700232554,0.7671410746721091,2.7129169777181765,-0.980035309228183,0.30292897251860446,-0.3025770869123972,0.49659904864423754,-0.45274711809482365,0.048211934796472365,-1.2042581055902233,0.24689976348114367,-0.15476681385717422,-0.2728238448155597,-0.18413660636999382,1.1865840591524877,-0.009327790283860563,2.7358317422764893,0.16225002844017103,0.8204396326290617,2.341300334418682,1.416015523904057,0.8204396326290617,0.16225002844017103,-0.5745330198140897,1.1865840591524877
| 3,375
|
Recurrent fractures
| 6
| 32
| 2.332795
| 0.019659
|
Q32P28,Q13126,P48735,O75718,Q96AY3,O75874
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,43,11,78,124,95
|
280,3114,78,95,800,2669,3099,1264,994,2749,2311,3211,11,1183,3342,1786,2898,43,1853,809,65,1197,126,124,2734,1058,1410,1412,1616,978,2009,1953
|
1.0831656426328216,-1.04369050099163,2.199402700232554,2.031985358818018,0.44164086630862914,-0.5439512892731678,-1.0118216311731156,0.13386805297961285,0.30292897251860446,-0.6052040240979027,-0.33242471265450957,-1.3668267524146023,4.470238014994655,0.19054865591249434,-2.6630754640461913,-0.09631286647900751,-0.7287703736920425,2.689966750135784,-0.1254926486793712,0.44164086630862914,2.341300334418682,0.19054865591249434,1.789127256491963,1.8136162149972994,-0.5745330198140897,0.27495414250230754,0.07685003800728503,0.07685003800728503,-0.009327790283860563,0.33082515613705404,-0.18413660636999382,-0.15476681385717422
| 3,375
|
Cysteine type peptidase activity
| 18
| 44
| 2.318563
| 0.020419
|
Q0VDG4,P07384,P51784,Q86UV5,O95630,Q9H8M7,Q99538,Q9P0U3,Q9NUQ7,Q13867,P42574,Q93009,Q93008,Q92890,Q9Y4E8,Q96RU2,Q96BN8,Q96K76
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
97,68,322,396,317,653,137,576,575,46,729,443,778,150,425,620,417,63
|
2236,1835,749,1032,317,68,3201,910,729,2429,2432,322,1849,97,2262,46,1516,1460,3326,1865,2214,1293,396,1399,1473,2074,150,2000,778,443,417,2151,63,620,137,1101,1154,653,575,576,2410,425,2170,1314
|
-0.3025770869123972,-0.1254926486793712,0.4691567512932392,0.27495414250230754,1.004988400356168,2.294161378716793,-1.334155331699041,0.358643578170959,0.49659904864423754,-0.39240070950050854,-0.39240070950050854,1.004988400356168,-0.1254926486793712,2.0078987123817007,-0.3025770869123972,2.666980836977603,0.019486354875994212,0.048211934796472365,-2.2080683522263658,-0.1254926486793712,-0.2728238448155597,0.13386805297961285,0.873480632258922,0.07685003800728503,0.048211934796472365,-0.21360297580762733,1.6163849582577512,-0.18413660636999382,0.4691567512932392,0.8204396326290617,0.8469920138668321,-0.24316559991811548,2.3648106652398435,0.6056479018936,1.6907038084850876,0.24689976348114367,0.21876491453847344,0.5784922208777676,0.6597506092154378,0.6597506092154378,-0.36236611826561227,0.8469920138668321,-0.24316559991811548,0.13386805297961285
| 3,375
|
Hyperthyroidism
| 6
| 11
| 2.316307
| 0.020542
|
Q96RR1,O00192,Q9BUK6,P12235,Q92766,Q92890
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
219,537,79,143,442,150
|
537,1257,143,1078,608,1575,2261,442,150,219,79
|
0.6866990592950521,0.13386805297961285,1.6412063989989234,0.24689976348114367,0.6056479018936,-0.009327790283860563,-0.3025770869123972,0.8204396326290617,1.6163849582577512,1.2635525405656844,2.199402700232554
| 3,375
|
Calcium ion import
| 9
| 13
| 2.315008
| 0.020612
|
Q9BPX6,O75844,Q8IYU8,Q9Y4W6,P21796,Q9NRA0,O14936,P17931,Q8WWC4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
465,471,502,578,700,109,383,305,286
|
383,471,1037,305,700,1179,1047,502,775,286,465,109,578
|
0.873480632258922,0.7671410746721091,0.27495414250230754,1.031106974534266,0.5239685462529114,0.19054865591249434,0.27495414250230754,0.7403936172598823,0.4691567512932392,1.0831656426328216,0.7938228645047847,1.935377141239234,0.6597506092154378
| 3,375
|
Autophagy
| 17
| 52
| 2.310535
| 0.020859
|
Q13885,A5D8V6,Q9Y484,Q9NT62,Q15388,P50542,Q9Y4P8,O95140,P08670,Q8N4H5,Q99497,Q13131,Q9NZ09,P68371,Q9NS69,Q9Y6G9,P63167
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
161,536,721,361,37,606,251,331,451,644,20,673,380,346,27,695,323
|
536,988,2946,750,1891,331,1696,2030,2180,451,2182,1498,700,1846,606,2127,1786,1851,2683,323,998,346,673,1983,1853,161,1655,1800,37,1807,1932,644,3259,2909,2462,2883,20,1940,2814,934,935,1155,27,361,380,1752,2168,1624,721,2170,251,695
|
0.6866990592950521,0.30292897251860446,-0.7910758719515134,0.4691567512932392,-0.15476681385717422,0.978809595175081,-0.0672262509964336,-0.21360297580762733,-0.2728238448155597,0.7938228645047847,-0.2728238448155597,0.019486354875994212,0.5239685462529114,-0.1254926486793712,0.6056479018936,-0.24316559991811548,-0.09631286647900751,-0.1254926486793712,-0.5439512892731678,1.004988400356168,0.30292897251860446,0.952569994453112,0.5512660173470204,-0.18413660636999382,-0.1254926486793712,1.5416250265376559,-0.038231613171792155,-0.09631286647900751,2.84988124164933,-0.09631286647900751,-0.15476681385717422,0.5784922208777676,-1.6643385894420446,-0.7287703736920425,-0.39240070950050854,-0.6977474581428348,3.582293433383776,-0.15476681385717422,-0.6359637761900813,0.358643578170959,0.358643578170959,0.21876491453847344,3.1424732722153843,0.9262690243148245,0.8999061013249092,-0.0672262509964336,-0.24316559991811548,-0.009327790283860563,0.5239685462529114,-0.24316559991811548,1.1865840591524877,0.5512660173470204
| 3,375
|
Glycosyltransferase
| 8
| 35
| 2.30673
| 0.02107
|
Q04446,Q16739,Q68CQ7,Q13126,P13807,Q2TAA5,P43490,Q9H488
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
261,133,170,43,167,309,14,121
|
1372,2527,859,2920,2857,1839,1962,1324,1560,2301,2828,802,167,1568,14,474,261,1186,2962,1513,43,133,309,170,1729,2932,882,2398,1402,2734,376,2403,121,2407,2852
|
0.07685003800728503,-0.45274711809482365,0.38638510613707605,-0.7598800080904538,-0.6977474581428348,-0.1254926486793712,-0.18413660636999382,0.10540172980990664,-0.009327790283860563,-0.33242471265450957,-0.6668117578076647,0.44164086630862914,1.491534732272122,-0.009327790283860563,3.797869337859779,0.7671410746721091,1.1349899370587961,0.19054865591249434,-0.7910758719515134,0.019486354875994212,2.689966750135784,1.7400097763933111,1.031106974534266,1.491534732272122,-0.0672262509964336,-0.7598800080904538,0.38638510613707605,-0.36236611826561227,0.07685003800728503,-0.5745330198140897,0.8999061013249092,-0.36236611826561227,1.8380591236082113,-0.36236611826561227,-0.6668117578076647
| 3,375
|
Regulation of lymphocyte activation
| 10
| 59
| 2.304721
| 0.021182
|
P00813,P49366,P14174,Q9HCL2,P12956,Q16512,O15360,P17931,P30825,O96005
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,130,101,158,8,307,115,305,26,283
|
1834,2022,2622,115,3305,1374,1173,283,1895,2857,0,3236,2825,318,1628,2031,2181,3327,8,101,1269,305,1387,26,1781,1179,756,729,865,130,2316,3257,1648,2056,2996,2502,2132,1515,1089,3156,307,1861,1660,1863,2338,611,2396,3286,776,2146,1012,504,2150,1533,1817,419,158,2231,3057
|
-0.1254926486793712,-0.21360297580762733,-0.5134593662434148,1.862456329832627,-2.0020086776833446,0.07685003800728503,0.19054865591249434,1.0831656426328216,-0.15476681385717422,-0.6977474581428348,8.05927987366474,-1.5313475075418816,-0.6668117578076647,1.004988400356168,-0.038231613171792155,-0.21360297580762733,-0.2728238448155597,-2.242657726526616,4.85801582075318,1.983768672818817,0.13386805297961285,1.031106974534266,0.07685003800728503,3.164753514554234,-0.09631286647900751,0.19054865591249434,0.4691567512932392,0.49659904864423754,0.38638510613707605,1.7645918959276166,-0.33242471265450957,-1.6643385894420446,-0.038231613171792155,-0.21360297580762733,-0.82235748271142,-0.42252790140681873,-0.24316559991811548,0.019486354875994212,0.24689976348114367,-1.1397880951540584,1.031106974534266,-0.1254926486793712,-0.038231613171792155,-0.1254926486793712,-0.33242471265450957,0.6056479018936,-0.36236611826561227,-1.8660637299899208,0.4691567512932392,-0.24316559991811548,0.30292897251860446,0.7403936172598823,-0.24316559991811548,0.019486354875994212,-0.09631286647900751,0.8469920138668321,1.5665946676492313,-0.2728238448155597,-0.9167120699523604
| 3,375
|
Immunologic hypersensitivity
| 11
| 31
| 2.302107
| 0.021329
|
P00813,O00192,Q9NZ08,Q08J23,Q9UJV9,Q9Y5L0,P50542,Q93009,Q92766,Q92890,Q9UID3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,537,103,41,577,382,606,443,442,150,423
|
537,1688,1892,0,1565,3080,1078,2677,3211,1846,1041,606,1084,608,2592,41,2899,1004,2267,3176,967,442,150,443,2159,1412,103,423,577,382,2018
|
0.6866990592950521,-0.0672262509964336,-0.15476681385717422,8.05927987366474,-0.009327790283860563,-0.980035309228183,0.24689976348114367,-0.5439512892731678,-1.3668267524146023,-0.1254926486793712,0.27495414250230754,0.6056479018936,0.24689976348114367,0.6056479018936,-0.4830577925150717,2.7358317422764893,-0.7287703736920425,0.30292897251860446,-0.3025770869123972,-1.2042581055902233,0.33082515613705404,0.8204396326290617,1.6163849582577512,0.8204396326290617,-0.24316559991811548,0.07685003800728503,1.983768672818817,0.8469920138668321,0.6597506092154378,0.8999061013249092,-0.18413660636999382
| 3,375
|
Immune response regulating cell surface receptor signaling pathway
| 10
| 30
| 2.297251
| 0.021604
|
P00813,P04439,Q14699,Q16512,P46379,Q96EP0,Q9UKG1,P17931,Q9NR50,Q07666
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,318,412,307,453,374,152,305,624,434
|
2984,1173,0,318,2304,305,1841,1387,2309,756,2585,453,604,2316,2683,2550,434,2996,1717,873,2764,1855,412,307,374,2351,624,1749,1485,152
|
-0.82235748271142,0.19054865591249434,8.05927987366474,1.004988400356168,-0.33242471265450957,1.031106974534266,-0.1254926486793712,0.07685003800728503,-0.33242471265450957,0.4691567512932392,-0.4830577925150717,0.7938228645047847,0.6056479018936,-0.33242471265450957,-0.5439512892731678,-0.45274711809482365,0.8204396326290617,-0.82235748271142,-0.0672262509964336,0.38638510613707605,-0.6052040240979027,-0.1254926486793712,0.8469920138668321,1.031106974534266,0.8999061013249092,-0.33242471265450957,0.6056479018936,-0.0672262509964336,0.048211934796472365,1.6163849582577512
| 3,375
|
Antigen receptor mediated signaling pathway
| 7
| 23
| 2.29257
| 0.021873
|
P00813,P04439,Q14699,Q96EP0,P17931,Q9NR50,Q07666
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,318,412,374,305,624,434
|
2984,1173,0,318,2304,305,1841,1387,2309,756,2585,604,2316,2683,434,1717,1855,412,374,2351,624,1749,1485
|
-0.82235748271142,0.19054865591249434,8.05927987366474,1.004988400356168,-0.33242471265450957,1.031106974534266,-0.1254926486793712,0.07685003800728503,-0.33242471265450957,0.4691567512932392,-0.4830577925150717,0.6056479018936,-0.33242471265450957,-0.5439512892731678,0.8204396326290617,-0.0672262509964336,-0.1254926486793712,0.8469920138668321,0.8999061013249092,-0.33242471265450957,0.6056479018936,-0.0672262509964336,0.048211934796472365
| 3,375
|
T cell receptor signaling pathway
| 7
| 23
| 2.29257
| 0.021873
|
P00813,P04439,Q14699,Q96EP0,P17931,Q9NR50,Q07666
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,318,412,374,305,624,434
|
2984,1173,0,318,2304,305,1841,1387,2309,756,2585,604,2316,2683,434,1717,1855,412,374,2351,624,1749,1485
|
-0.82235748271142,0.19054865591249434,8.05927987366474,1.004988400356168,-0.33242471265450957,1.031106974534266,-0.1254926486793712,0.07685003800728503,-0.33242471265450957,0.4691567512932392,-0.4830577925150717,0.6056479018936,-0.33242471265450957,-0.5439512892731678,0.8204396326290617,-0.0672262509964336,-0.1254926486793712,0.8469920138668321,0.8999061013249092,-0.33242471265450957,0.6056479018936,-0.0672262509964336,0.048211934796472365
| 3,375
|
FAD/NAD(P)-binding domain superfamily [IPR036188]
| 6
| 18
| 2.286754
| 0.02221
|
Q14534,P43304,O95831,Q9UHG3,Q96CU9,Q6NUM9
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
356,200,449,13,86,348
|
2824,449,450,1326,2489,1219,2752,200,2124,356,1519,1091,348,774,2070,86,2090,13
|
-0.6668117578076647,0.7938228645047847,0.7938228645047847,0.10540172980990664,-0.42252790140681873,0.16225002844017103,-0.6052040240979027,1.340025485497747,-0.24316559991811548,0.9262690243148245,0.019486354875994212,0.24689976348114367,0.952569994453112,0.4691567512932392,-0.21360297580762733,2.1039880520769403,-0.21360297580762733,3.9895804689666323
| 3,375
|
Mitochondrial fatty acid beta oxidation
| 6
| 16
| 2.283541
| 0.022398
|
P42126,P11310,Q9BR61,Q16836,P30084,Q9Y305
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
408,1,275,15,204,550
|
1316,2113,602,1,1842,204,2122,408,1571,2756,2758,15,2931,275,2354,550
|
0.10540172980990664,-0.24316559991811548,0.6056479018936,7.367385577094042,-0.1254926486793712,1.3145887721057432,-0.24316559991811548,0.8469920138668321,-0.009327790283860563,-0.6052040240979027,-0.6052040240979027,3.797869337859779,-0.7598800080904538,1.1091068208502726,-0.33242471265450957,0.6866990592950521
| 3,375
|
Mitochondrial transport
| 17
| 89
| 2.283419
| 0.022406
|
P49841,O43772,P23786,Q99595,O60830,Q15388,P00846,P55786,Q5JRX3,P12235,O95140,Q96EK5,P50416,Q96EP0,Q9NS69,Q8WWC4,P30536
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,33,34,64,4,37,260,7,296,143,331,351,266,374,27,286,341
|
3153,512,580,1216,3231,1886,33,4,2297,947,3126,698,1891,331,2856,1894,449,1696,260,1322,1174,1073,2030,949,2181,143,1498,34,1177,2037,2674,2540,341,1973,1844,1571,1847,3045,1848,730,805,32,266,2317,917,7,1086,2681,2548,999,673,2207,37,2966,3365,437,768,296,2600,1294,924,1007,644,1814,1667,286,1098,351,374,1606,64,1356,3262,3093,1308,1156,27,2096,2820,400,2740,1750,1485,2235,3276,1066,3370,2524,2477
|
-1.1397880951540584,0.713579835070738,0.6327337919013768,0.16225002844017103,-1.4653079613874214,-0.15476681385717422,3.0081206146023467,5.415645674566234,-0.33242471265450957,0.33082515613705404,-1.075641485634037,0.5239685462529114,-0.15476681385717422,0.978809595175081,-0.6977474581428348,-0.15476681385717422,0.7938228645047847,-0.0672262509964336,1.1349899370587961,0.10540172980990664,0.19054865591249434,0.24689976348114367,-0.21360297580762733,0.33082515613705404,-0.2728238448155597,1.6412063989989234,0.019486354875994212,2.985614892363513,0.19054865591249434,-0.21360297580762733,-0.5439512892731678,-0.45274711809482365,0.952569994453112,-0.18413660636999382,-0.1254926486793712,-0.009327790283860563,-0.1254926486793712,-0.9167120699523604,-0.1254926486793712,0.49659904864423754,0.44164086630862914,3.030593559630485,1.1091068208502726,-0.33242471265450957,0.358643578170959,4.918525847007338,0.24689976348114367,-0.5439512892731678,-0.45274711809482365,0.30292897251860446,0.5512660173470204,-0.2728238448155597,2.84988124164933,-0.7910758719515134,-4.017752483133644,0.8204396326290617,0.4691567512932392,1.057165873125376,-0.4830577925150717,0.13386805297961285,0.358643578170959,0.30292897251860446,0.5784922208777676,-0.09631286647900751,-0.038231613171792155,1.0831656426328216,0.24689976348114367,0.952569994453112,0.8999061013249092,-0.009327790283860563,2.3648106652398435,0.10540172980990664,-1.6643385894420446,-0.980035309228183,0.13386805297961285,0.21876491453847344,3.1424732722153843,-0.21360297580762733,-0.6359637761900813,0.873480632258922,-0.5745330198140897,-0.0672262509964336,0.048211934796472365,-0.2728238448155597,-1.7648689174206336,0.27495414250230754,-4.783944066538735,-0.42252790140681873,-0.39240070950050854
| 3,375
|
Intrinsic component of endoplasmic reticulum membrane
| 18
| 53
| 2.28274
| 0.022446
|
Q86YN1,Q9Y282,O75844,Q9NQC3,P49069,Q96S52,Q969X5,P04439,Q03518,Q86XL3,Q9HCU5,P10321,Q8N4V1,Q9C0E8,Q15629,Q8TCT9,Q9H490,Q8TB61
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
459,99,471,230,409,273,135,318,232,44,336,452,81,377,211,564,221,546
|
2526,2237,3023,3097,471,2110,1766,318,452,665,1272,910,409,2317,1505,2257,232,1392,3120,2903,211,764,2391,2067,44,459,81,589,546,564,1473,1096,135,2346,273,2083,1298,2515,377,221,336,2775,230,1683,1544,1160,2287,2356,3302,2742,99,1253,1832
|
-0.45274711809482365,-0.3025770869123972,-0.8851760478860837,-1.0118216311731156,0.7671410746721091,-0.24316559991811548,-0.09631286647900751,1.004988400356168,0.7938228645047847,0.5512660173470204,0.13386805297961285,0.358643578170959,0.8469920138668321,-0.33242471265450957,0.019486354875994212,-0.3025770869123972,1.212296082730813,0.07685003800728503,-1.04369050099163,-0.7287703736920425,1.2890979463364292,0.4691567512932392,-0.36236611826561227,-0.21360297580762733,2.689966750135784,0.7938228645047847,2.1517785208460363,0.6327337919013768,0.6866990592950521,0.6597506092154378,0.048211934796472365,0.24689976348114367,1.7153805361397676,-0.33242471265450957,1.1091068208502726,-0.21360297580762733,0.13386805297961285,-0.42252790140681873,0.8999061013249092,1.2635525405656844,0.978809595175081,-0.6052040240979027,1.2379520800421246,-0.038231613171792155,0.019486354875994212,0.21876491453847344,-0.3025770869123972,-0.33242471265450957,-1.9338917553280288,-0.5745330198140897,2.0078987123817007,0.16225002844017103,-0.09631286647900751
| 3,375
|
Positive regulation of immune response
| 22
| 79
| 2.280658
| 0.022569
|
P00813,Q12846,P12956,Q99497,Q96PK6,Q9UKG1,Q9NUD5,Q9UHD2,Q14699,Q16512,P17931,Q9BUI4,Q07666,Q7Z434,P04439,Q8ND56,P46379,Q9NR50,Q12933,P49770,Q9NRA0,Q96EP0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,527,8,20,681,152,685,689,412,307,305,189,434,196,318,462,453,624,96,604,109,374
|
2781,2984,1374,2482,1891,900,1173,1895,0,3236,2825,318,2030,1628,2181,3327,8,1267,2304,305,1841,952,1387,2038,2309,2426,3174,756,956,865,2585,453,604,2316,831,2959,2683,1648,2550,671,434,1229,2996,527,2502,96,1717,873,2764,1855,412,2446,1927,307,1660,1863,2338,196,462,2567,1202,374,1533,681,2463,20,3137,189,2351,2231,624,109,685,3057,2409,689,1749,1485,152
|
-0.6359637761900813,-0.82235748271142,0.07685003800728503,-0.42252790140681873,-0.15476681385717422,0.358643578170959,0.19054865591249434,-0.15476681385717422,8.05927987366474,-1.5313475075418816,-0.6668117578076647,1.004988400356168,-0.21360297580762733,-0.038231613171792155,-0.2728238448155597,-2.242657726526616,4.85801582075318,0.13386805297961285,-0.33242471265450957,1.031106974534266,-0.1254926486793712,0.33082515613705404,0.07685003800728503,-0.21360297580762733,-0.33242471265450957,-0.39240070950050854,-1.2042581055902233,0.4691567512932392,0.33082515613705404,0.38638510613707605,-0.4830577925150717,0.7938228645047847,0.6056479018936,-0.33242471265450957,0.41405059073486755,-0.7910758719515134,-0.5439512892731678,-0.038231613171792155,-0.45274711809482365,0.5512660173470204,0.8204396326290617,0.16225002844017103,-0.82235748271142,0.713579835070738,-0.42252790140681873,2.031985358818018,-0.0672262509964336,0.38638510613707605,-0.6052040240979027,-0.1254926486793712,0.8469920138668321,-0.39240070950050854,-0.15476681385717422,1.031106974534266,-0.038231613171792155,-0.1254926486793712,-0.33242471265450957,1.3654085471612543,0.7938228645047847,-0.45274711809482365,0.19054865591249434,0.8999061013249092,0.019486354875994212,0.5512660173470204,-0.39240070950050854,3.582293433383776,-1.075641485634037,1.39073841091754,-0.33242471265450957,-0.2728238448155597,0.6056479018936,1.935377141239234,0.5512660173470204,-0.9167120699523604,-0.36236611826561227,0.5512660173470204,-0.0672262509964336,0.048211934796472365,1.6163849582577512
| 3,375
|
Peroxisomal lipid metabolism
| 7
| 13
| 2.274269
| 0.02295
|
O75521,P51648,Q9BY49,O14734,Q5T8D3,Q15067,Q9UKG9
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
132,410,203,237,500,737,160
|
237,1371,1491,132,1771,2118,410,1975,737,500,203,822,160
|
1.1865840591524877,0.07685003800728503,0.019486354875994212,1.7400097763933111,-0.09631286647900751,-0.24316559991811548,0.8469920138668321,-0.18413660636999382,0.49659904864423754,0.7403936172598823,1.340025485497747,0.44164086630862914,1.5665946676492313
| 3,375
|
Mitochondrion organization
| 51
| 204
| 2.266626
| 0.023413
|
O75880,O60830,O75153,P55786,O00170,P12235,O43819,Q9BSK2,Q99497,Q9Y3B8,Q9NS69,Q8WWC4,P03886,P49841,Q5JRX3,Q15388,Q6DKK2,Q96BY7,Q69YU5,Q9Y4W6,O43678,P42858,P14406,O43676,Q96RL7,Q3ZCQ8,Q99595,Q7L592,Q9NVT9,O95831,Q13505,Q9BUK6,O95140,O14737,O75306,Q96CU9,Q9H4A6,P48507,P30536,Q9Y2R0,Q9NT62,Q9BWH2,Q96EY1,P50542,Q9Y4P8,Q9UH62,Q9GZT3,Q96A26,Q8N4H5,Q96EP0,O95168
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,4,6,7,512,143,385,18,20,424,27,286,31,32,296,37,165,298,171,578,291,175,49,177,51,437,64,562,595,449,334,79,331,580,581,86,622,342,341,363,361,359,504,606,251,510,378,649,644,374,493
|
3153,512,1834,897,3096,580,1216,3231,1886,2665,177,291,385,945,4,6,2530,1690,581,2297,947,2241,1435,129,1891,331,493,2029,901,2856,1894,449,1695,1696,3079,3236,31,1962,3237,1322,1174,2030,949,2301,1495,2181,1630,143,49,1498,700,2190,2584,1909,2674,2540,341,1973,2426,1569,667,3010,1571,175,1847,2371,1848,342,730,805,32,1913,606,1084,1572,2317,1573,917,832,7,2682,1851,2548,871,3270,1047,2638,999,673,3118,1853,334,2135,1800,2207,1517,37,3205,2966,2211,3365,1596,2212,2059,437,768,2062,296,1462,1661,3275,171,165,1138,2454,562,1992,1294,2933,1932,924,1007,2268,1813,2563,644,2269,775,2343,1814,1667,3177,1869,286,649,298,86,1098,374,504,2883,3107,1606,51,2464,20,1244,64,3137,2974,1356,1408,651,3301,18,2226,2700,79,3109,359,3262,378,3093,936,715,622,819,1308,2007,27,361,3057,820,746,595,821,787,1209,2095,2096,3006,2820,2660,510,3076,2740,1485,3193,2235,363,1213,3276,424,721,2170,251,578,1066,3370,2524,2477,694,1548,943
|
-1.1397880951540584,0.713579835070738,-0.1254926486793712,0.358643578170959,-1.0118216311731156,0.6327337919013768,0.16225002844017103,-1.4653079613874214,-0.15476681385717422,-0.5439512892731678,1.441240326714265,1.057165873125376,0.873480632258922,0.33082515613705404,5.415645674566234,5.078968659420913,-0.45274711809482365,-0.0672262509964336,0.6327337919013768,-0.33242471265450957,0.33082515613705404,-0.3025770869123972,0.048211934796472365,1.7645918959276166,-0.15476681385717422,0.978809595175081,0.7403936172598823,-0.21360297580762733,0.358643578170959,-0.6977474581428348,-0.15476681385717422,0.7938228645047847,-0.0672262509964336,-0.0672262509964336,-0.980035309228183,-1.5313475075418816,3.030593559630485,-0.18413660636999382,-1.5313475075418816,0.10540172980990664,0.19054865591249434,-0.21360297580762733,0.33082515613705404,-0.33242471265450957,0.019486354875994212,-0.2728238448155597,-0.038231613171792155,1.6412063989989234,2.6209010513937283,0.019486354875994212,0.5239685462529114,-0.2728238448155597,-0.4830577925150717,-0.15476681385717422,-0.5439512892731678,-0.45274711809482365,0.952569994453112,-0.18413660636999382,-0.39240070950050854,-0.009327790283860563,0.5512660173470204,-0.8537243644783261,-0.009327790283860563,1.4664132535336514,-0.1254926486793712,-0.36236611826561227,-0.1254926486793712,0.952569994453112,0.49659904864423754,0.44164086630862914,3.030593559630485,-0.15476681385717422,0.6056479018936,0.24689976348114367,-0.009327790283860563,-0.33242471265450957,-0.009327790283860563,0.358643578170959,0.41405059073486755,4.918525847007338,-0.5439512892731678,-0.1254926486793712,-0.45274711809482365,0.38638510613707605,-1.7312845351077755,0.27495414250230754,-0.5134593662434148,0.30292897251860446,0.5512660173470204,-1.04369050099163,-0.1254926486793712,0.978809595175081,-0.24316559991811548,-0.09631286647900751,-0.2728238448155597,0.019486354875994212,2.84988124164933,-1.334155331699041,-0.7910758719515134,-0.2728238448155597,-4.017752483133644,-0.009327790283860563,-0.2728238448155597,-0.21360297580762733,0.8204396326290617,0.4691567512932392,-0.21360297580762733,1.057165873125376,0.048211934796472365,-0.038231613171792155,-1.7648689174206336,1.491534732272122,1.516605184692839,0.21876491453847344,-0.39240070950050854,0.6597506092154378,-0.18413660636999382,0.13386805297961285,-0.7598800080904538,-0.15476681385717422,0.358643578170959,0.30292897251860446,-0.3025770869123972,-0.09631286647900751,-0.45274711809482365,0.5784922208777676,-0.3025770869123972,0.4691567512932392,-0.33242471265450957,-0.09631286647900751,-0.038231613171792155,-1.2042581055902233,-0.1254926486793712,1.0831656426328216,0.5784922208777676,1.057165873125376,2.1039880520769403,0.24689976348114367,0.8999061013249092,0.7403936172598823,-0.6977474581428348,-1.0118216311731156,-0.009327790283860563,2.5746757906678,-0.39240070950050854,3.582293433383776,0.16225002844017103,2.3648106652398435,-1.075641485634037,-0.7910758719515134,0.10540172980990664,0.07685003800728503,0.5784922208777676,-1.9338917553280288,3.6904267756578513,-0.2728238448155597,-0.5439512892731678,2.199402700232554,-1.0118216311731156,0.9262690243148245,-1.6643385894420446,0.8999061013249092,-0.980035309228183,0.358643578170959,0.5239685462529114,0.6056479018936,0.44164086630862914,0.13386805297961285,-0.18413660636999382,3.1424732722153843,0.9262690243148245,-0.9167120699523604,0.44164086630862914,0.49659904864423754,0.6327337919013768,0.44164086630862914,0.4691567512932392,0.19054865591249434,-0.21360297580762733,-0.21360297580762733,-0.82235748271142,-0.6359637761900813,-0.5134593662434148,0.7403936172598823,-0.948331973940958,-0.5745330198140897,0.048211934796472365,-1.2690482472817965,-0.2728238448155597,0.9262690243148245,0.19054865591249434,-1.7648689174206336,0.8469920138668321,0.5239685462529114,-0.24316559991811548,1.1865840591524877,0.6597506092154378,0.27495414250230754,-4.783944066538735,-0.42252790140681873,-0.39240070950050854,0.5512660173470204,0.019486354875994212,0.358643578170959
| 3,375
|
Phosphatase
| 9
| 32
| 2.261599
| 0.023722
|
Q16537,Q86YN1,Q08623,Q9NPH0,P49902,Q9H857,O95140,Q9NX62,Q86UY8
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
155,459,162,2,343,445,331,215,122
|
1367,1689,1167,331,1627,3306,1567,728,3061,1126,343,2836,2377,870,526,2898,162,1924,155,838,122,459,1932,1355,2815,1613,1302,2405,445,1679,2,215
|
0.07685003800728503,-0.0672262509964336,0.19054865591249434,0.978809595175081,-0.038231613171792155,-2.036174700270587,-0.009327790283860563,0.49659904864423754,-0.948331973940958,0.21876491453847344,0.952569994453112,-0.6668117578076647,-0.36236611826561227,0.38638510613707605,0.713579835070738,-0.7287703736920425,1.516605184692839,-0.15476681385717422,1.5665946676492313,0.41405059073486755,1.8136162149972994,0.7938228645047847,-0.15476681385717422,0.10540172980990664,-0.6359637761900813,-0.009327790283860563,0.13386805297961285,-0.36236611826561227,0.8204396326290617,-0.038231613171792155,6.8766404995232415,1.2890979463364292
| 3,375
|
Early endosome
| 24
| 104
| 2.250721
| 0.024403
|
Q9P253,Q8IV08,Q7Z3T8,Q9HC07,Q9UJY4,Q9UKG1,P42566,Q8N668,P31751,Q5T1M5,P61421,Q14699,P42858,Q15276,Q8N3F8,P04439,O95630,P41440,Q86YV9,Q8N4V1,O43752,Q96L92,Q96PE3,Q8WUH2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,3,395,139,279,152,265,285,154,164,293,412,175,176,61,318,317,321,460,81,209,87,94,373
|
1165,2294,2781,209,1376,1319,2175,658,1492,2240,2025,2027,699,317,3236,2825,318,2713,452,2181,3192,1701,3042,1328,2189,2190,2309,1909,2862,154,2426,1500,321,265,175,1450,2895,1711,293,1184,1388,2898,872,735,2964,3366,2503,1516,412,1858,2506,176,2870,2967,766,164,2336,1394,395,771,1931,460,3,61,81,285,373,2345,1009,842,2148,816,2732,1817,87,94,1606,1203,3362,2814,2084,2515,2653,2607,592,1303,1949,139,2091,128,1824,1161,1363,1826,1107,279,3036,152,1622,940,1251,2981,2942,1489
|
0.19054865591249434,-0.33242471265450957,-0.6359637761900813,1.2890979463364292,0.07685003800728503,0.10540172980990664,-0.2728238448155597,0.5512660173470204,0.019486354875994212,-0.3025770869123972,-0.21360297580762733,-0.21360297580762733,0.5239685462529114,1.004988400356168,-1.5313475075418816,-0.6668117578076647,1.004988400356168,-0.5745330198140897,0.7938228645047847,-0.2728238448155597,-1.2690482472817965,-0.0672262509964336,-0.9167120699523604,0.10540172980990664,-0.2728238448155597,-0.2728238448155597,-0.33242471265450957,-0.15476681385717422,-0.6977474581428348,1.5665946676492313,-0.39240070950050854,0.019486354875994212,1.004988400356168,1.1091068208502726,1.4664132535336514,0.048211934796472365,-0.7287703736920425,-0.0672262509964336,1.057165873125376,0.19054865591249434,0.07685003800728503,-0.7287703736920425,0.38638510613707605,0.49659904864423754,-0.7910758719515134,-4.055519423800208,-0.42252790140681873,0.019486354875994212,0.8469920138668321,-0.1254926486793712,-0.42252790140681873,1.4664132535336514,-0.6977474581428348,-0.7910758719515134,0.4691567512932392,1.516605184692839,-0.33242471265450957,0.07685003800728503,0.873480632258922,0.4691567512932392,-0.15476681385717422,0.7938228645047847,5.727500366668169,2.388281917660161,2.1517785208460363,1.0831656426328216,0.8999061013249092,-0.33242471265450957,0.30292897251860446,0.41405059073486755,-0.24316559991811548,0.44164086630862914,-0.5745330198140897,-0.09631286647900751,2.1039880520769403,2.0560289253619395,-0.009327790283860563,0.19054865591249434,-3.6804985715334615,-0.6359637761900813,-0.21360297580762733,-0.42252790140681873,-0.5134593662434148,-0.4830577925150717,0.6327337919013768,0.13386805297961285,-0.15476681385717422,1.6907038084850876,-0.21360297580762733,1.789127256491963,-0.09631286647900751,0.21876491453847344,0.10540172980990664,-0.09631286647900751,0.24689976348114367,1.1091068208502726,-0.8851760478860837,1.6163849582577512,-0.009327790283860563,0.358643578170959,0.16225002844017103,-0.7910758719515134,-0.7598800080904538,0.048211934796472365
| 3,375
|
Antigen processing and presentation of peptide antigen
| 7
| 11
| 2.248671
| 0.024533
|
Q6P179,Q9NZ08,P04439,Q99538,Q03518,P10321,P14735
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
676,103,318,137,232,452,519
|
318,452,519,665,910,1222,232,676,137,103,1826
|
1.004988400356168,0.7938228645047847,0.713579835070738,0.5512660173470204,0.358643578170959,0.16225002844017103,1.212296082730813,0.5512660173470204,1.6907038084850876,1.983768672818817,-0.09631286647900751
| 3,375
|
Positive regulation of growth
| 14
| 51
| 2.246199
| 0.024691
|
P78344,P51812,O75312,Q9HCL2,Q6PJG6,Q14699,Q6KC79,P58546,Q9BSK2,Q15418,Q7L576,Q9Y3B8,O95684,Q96K76
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
194,239,404,158,201,412,456,454,18,53,479,424,92,63
|
3160,1428,1687,2709,404,1435,2110,92,1698,2304,1443,2749,2752,1707,912,606,239,2496,454,2051,3257,194,3084,1650,1796,1187,1980,2134,2965,412,53,1348,1520,3086,456,201,479,2457,2268,63,18,2889,158,2890,2286,1107,2470,487,1163,424,1067
|
-1.1719828815512887,0.048211934796472365,-0.0672262509964336,-0.5745330198140897,0.8469920138668321,0.048211934796472365,-0.24316559991811548,2.0560289253619395,-0.0672262509964336,-0.33242471265450957,0.048211934796472365,-0.6052040240979027,-0.6052040240979027,-0.0672262509964336,0.358643578170959,0.6056479018936,1.1865840591524877,-0.42252790140681873,0.7938228645047847,-0.21360297580762733,-1.6643385894420446,1.3654085471612543,-0.980035309228183,-0.038231613171792155,-0.09631286647900751,0.19054865591249434,-0.18413660636999382,-0.24316559991811548,-0.7910758719515134,0.8469920138668321,2.4817813149505383,0.10540172980990664,0.019486354875994212,-0.980035309228183,0.7938228645047847,1.340025485497747,0.7671410746721091,-0.39240070950050854,-0.3025770869123972,2.3648106652398435,3.6904267756578513,-0.6977474581428348,1.5665946676492313,-0.6977474581428348,-0.3025770869123972,0.24689976348114367,-0.39240070950050854,0.7671410746721091,0.21876491453847344,0.8469920138668321,0.27495414250230754
| 3,375
|
Alzheimers disease
| 15
| 86
| 2.243594
| 0.024859
|
P49841,Q12933,Q13885,P07384,Q96BY7,Q9NQC3,O95197,P49721,P60900,Q9Y4P8,P12235,P07437,P68371,P28074,P31751
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
32,96,161,68,298,230,259,40,344,251,143,264,346,238,154
|
2019,2621,1835,1369,2479,1551,259,2712,2713,1174,2300,68,264,1495,143,1122,519,1037,3201,1700,1386,1498,907,803,700,2424,829,1270,1905,2189,2790,556,472,238,2309,2674,154,863,1179,2753,1500,1846,729,1783,1847,2372,995,1041,2680,40,32,2432,2795,344,2759,2204,1790,998,346,1047,872,1511,1049,1188,96,1000,836,161,1800,2445,2873,775,2345,298,464,2277,1940,2974,934,935,360,230,2470,1952,857,251
|
-0.21360297580762733,-0.5134593662434148,-0.1254926486793712,0.07685003800728503,-0.42252790140681873,-0.009327790283860563,1.1349899370587961,-0.5745330198140897,-0.5745330198140897,0.19054865591249434,-0.33242471265450957,2.294161378716793,1.1091068208502726,0.019486354875994212,1.6412063989989234,0.21876491453847344,0.713579835070738,0.27495414250230754,-1.334155331699041,-0.0672262509964336,0.07685003800728503,0.019486354875994212,0.358643578170959,0.44164086630862914,0.5239685462529114,-0.39240070950050854,0.41405059073486755,0.13386805297961285,-0.15476681385717422,-0.2728238448155597,-0.6359637761900813,0.6597506092154378,0.7671410746721091,1.1865840591524877,-0.33242471265450957,-0.5439512892731678,1.5665946676492313,0.38638510613707605,0.19054865591249434,-0.6052040240979027,0.019486354875994212,-0.1254926486793712,0.49659904864423754,-0.09631286647900751,-0.1254926486793712,-0.36236611826561227,0.30292897251860446,0.27495414250230754,-0.5439512892731678,2.7358317422764893,3.030593559630485,-0.39240070950050854,-0.6359637761900813,0.952569994453112,-0.6052040240979027,-0.2728238448155597,-0.09631286647900751,0.30292897251860446,0.952569994453112,0.27495414250230754,0.38638510613707605,0.019486354875994212,0.27495414250230754,0.19054865591249434,2.031985358818018,0.30292897251860446,0.41405059073486755,1.5416250265376559,-0.09631286647900751,-0.39240070950050854,-0.6977474581428348,0.4691567512932392,-0.33242471265450957,1.057165873125376,0.7938228645047847,-0.3025770869123972,-0.15476681385717422,-0.7910758719515134,0.358643578170959,0.358643578170959,0.9262690243148245,1.2379520800421246,-0.39240070950050854,-0.15476681385717422,0.41405059073486755,1.1865840591524877
| 3,375
|
Dehydrogenase
| 11
| 58
| 2.243494
| 0.024865
|
Q13423,Q8N8N7,P43304,O94788,O95831,Q9BY49,P00390,Q96CU9,Q00796,P30837,P03886
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
262,5,200,75,449,203,450,86,432,55,31
|
1028,2529,1690,581,75,449,1896,1262,450,31,2712,726,1118,992,1326,1120,1075,1385,1329,1635,828,2584,1908,55,1219,1273,1502,2719,200,2047,3307,1784,475,1573,1642,3244,1576,2682,432,2799,2960,262,2505,2212,1091,1136,2602,814,5,647,1528,86,2974,203,2090,1683,2096,1249
|
0.27495414250230754,-0.45274711809482365,-0.0672262509964336,0.6327337919013768,2.223153155757611,0.7938228645047847,-0.15476681385717422,0.13386805297961285,0.7938228645047847,3.030593559630485,-0.5745330198140897,0.49659904864423754,0.21876491453847344,0.30292897251860446,0.10540172980990664,0.21876491453847344,0.24689976348114367,0.07685003800728503,0.10540172980990664,-0.038231613171792155,0.41405059073486755,-0.4830577925150717,-0.15476681385717422,2.4584637978137454,0.16225002844017103,0.13386805297961285,0.019486354875994212,-0.5745330198140897,1.340025485497747,-0.21360297580762733,-2.036174700270587,-0.09631286647900751,0.7671410746721091,-0.009327790283860563,-0.038231613171792155,-1.5644818109642689,-0.009327790283860563,-0.5439512892731678,0.8204396326290617,-0.6359637761900813,-0.7910758719515134,1.1349899370587961,-0.42252790140681873,-0.2728238448155597,0.24689976348114367,0.21876491453847344,-0.4830577925150717,0.44164086630862914,5.317208932732073,0.5784922208777676,0.019486354875994212,2.1039880520769403,-0.7910758719515134,1.340025485497747,-0.21360297580762733,-0.038231613171792155,-0.21360297580762733,0.16225002844017103
| 3,375
|
Kinase
| 37
| 112
| 2.242055
| 0.024958
|
Q13546,P11802,P41240,O14936,Q4G0N4,Q9NVE7,Q9UHD2,P31751,P49841,Q6P3W7,Q14012,P04183,P27144,Q16512,O00443,Q99640,Q15418,Q13131,P49840,Q9Y3D8,P46020,O14976,P55263,O14578,O14757,Q13572,Q9BVS4,Q15120,Q9UBF8,O43683,Q13464,Q9HA64,Q13555,Q9NRA0,Q9BRR6,P24941,P51812
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
528,633,756,383,23,289,689,154,32,677,810,801,664,307,795,444,53,673,805,329,192,191,193,579,330,585,742,90,747,470,104,236,355,109,118,367,239
|
795,1429,579,330,383,191,2984,470,1378,2577,1171,2670,2244,1961,801,1698,1561,633,1441,904,3041,1773,2788,1634,2364,1077,1217,1386,1498,1445,2186,1176,367,664,2189,2309,2861,154,1178,3116,1500,756,1846,192,995,805,32,3250,2048,239,917,958,2127,2318,193,2376,998,1454,1648,1280,1047,2055,872,2550,2899,673,873,2764,1799,807,104,2927,528,355,585,810,3104,90,2139,53,3147,307,1859,1348,1051,23,677,2454,1664,2562,3264,967,2272,1013,1476,1940,444,2514,118,1409,742,2656,1153,2351,236,109,289,2408,747,689,1825,329
|
0.44164086630862914,0.048211934796472365,0.6327337919013768,0.978809595175081,0.873480632258922,1.3654085471612543,-0.82235748271142,0.7671410746721091,0.07685003800728503,-0.4830577925150717,0.19054865591249434,-0.5439512892731678,-0.3025770869123972,-0.18413660636999382,0.44164086630862914,-0.0672262509964336,-0.009327790283860563,0.5784922208777676,0.048211934796472365,0.358643578170959,-0.9167120699523604,-0.09631286647900751,-0.6359637761900813,-0.038231613171792155,-0.36236611826561227,0.24689976348114367,0.16225002844017103,0.07685003800728503,0.019486354875994212,0.048211934796472365,-0.2728238448155597,0.19054865591249434,0.8999061013249092,0.5512660173470204,-0.2728238448155597,-0.33242471265450957,-0.6977474581428348,1.5665946676492313,0.19054865591249434,-1.04369050099163,0.019486354875994212,0.4691567512932392,-0.1254926486793712,1.3654085471612543,0.30292897251860446,0.44164086630862914,3.030593559630485,-1.5976919926421527,-0.21360297580762733,1.1865840591524877,0.358643578170959,0.33082515613705404,-0.24316559991811548,-0.33242471265450957,1.3654085471612543,-0.36236611826561227,0.30292897251860446,0.048211934796472365,-0.038231613171792155,0.13386805297961285,0.27495414250230754,-0.21360297580762733,0.38638510613707605,-0.45274711809482365,-0.7287703736920425,0.5512660173470204,0.38638510613707605,-0.6052040240979027,-0.09631286647900751,0.44164086630862914,1.9595949228824863,-0.7598800080904538,0.713579835070738,0.9262690243148245,0.6327337919013768,0.44164086630862914,-1.0118216311731156,2.0800297213070706,-0.24316559991811548,2.4817813149505383,-1.1076741576662066,1.031106974534266,-0.1254926486793712,0.10540172980990664,0.27495414250230754,3.4077973078556516,0.5512660173470204,-0.39240070950050854,-0.038231613171792155,-0.45274711809482365,-1.6977743138917556,0.33082515613705404,-0.3025770869123972,0.30292897251860446,0.048211934796472365,-0.15476681385717422,0.8204396326290617,-0.42252790140681873,1.862456329832627,0.07685003800728503,0.49659904864423754,-0.5134593662434148,0.21876491453847344,-0.33242471265450957,1.212296082730813,1.935377141239234,1.0831656426328216,-0.36236611826561227,0.49659904864423754,0.5512660173470204,-0.09631286647900751,1.004988400356168
| 3,375
|
Peptidyl proline modification
| 7
| 34
| 2.240318
| 0.02507
|
Q32P28,O15460,P13674,O75718,Q9NWM8,Q96AY3,Q8N543
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,74,76,78,83,124,123
|
512,74,1029,78,1264,76,2749,2583,2674,862,2042,1130,3067,1390,1188,874,3134,1189,2963,1392,2597,65,164,123,1094,124,3089,650,1103,83,2778,596,1486,3274
|
0.713579835070738,2.223153155757611,0.27495414250230754,2.199402700232554,0.13386805297961285,2.223153155757611,-0.6052040240979027,-0.4830577925150717,-0.5439512892731678,0.38638510613707605,-0.21360297580762733,0.21876491453847344,-0.948331973940958,0.07685003800728503,0.19054865591249434,0.38638510613707605,-1.075641485634037,0.19054865591249434,-0.7910758719515134,0.07685003800728503,-0.4830577925150717,2.341300334418682,1.516605184692839,1.8136162149972994,0.24689976348114367,1.8136162149972994,-0.980035309228183,0.5784922208777676,0.24689976348114367,2.1279042192938276,-0.6052040240979027,0.6327337919013768,0.048211934796472365,-1.7312845351077755
| 3,375
|
Abnormality of the parathyroid gland
| 9
| 21
| 2.212497
| 0.026932
|
O00192,Q08J23,P48735,Q92766,O75874,Q92890,P00403,Q15813,P03886
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
537,41,11,442,95,150,494,435,31
|
537,95,494,31,2031,1078,3256,2122,11,3011,608,2758,2898,41,435,1808,2343,442,150,1096,2149
|
0.6866990592950521,2.031985358818018,0.7403936172598823,3.030593559630485,-0.21360297580762733,0.24689976348114367,-1.6643385894420446,-0.24316559991811548,4.470238014994655,-0.8537243644783261,0.6056479018936,-0.6052040240979027,-0.7287703736920425,2.7358317422764893,0.8204396326290617,-0.09631286647900751,-0.33242471265450957,0.8204396326290617,1.6163849582577512,0.24689976348114367,-0.24316559991811548
| 3,375
|
Cellular response to ketone
| 7
| 21
| 2.210994
| 0.027036
|
Q8IZH2,O95831,P11802,Q9NRA0,O43823,Q99497,Q9H4A6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
642,449,633,109,210,20,622
|
210,2577,449,2421,633,1444,2037,2717,1507,1716,673,1653,1051,1663,642,968,1202,20,622,1741,109
|
1.2890979463364292,-0.4830577925150717,0.7938228645047847,-0.39240070950050854,0.5784922208777676,0.048211934796472365,-0.21360297580762733,-0.5745330198140897,0.019486354875994212,-0.0672262509964336,0.5512660173470204,-0.038231613171792155,0.27495414250230754,-0.038231613171792155,0.5784922208777676,0.33082515613705404,0.19054865591249434,3.582293433383776,0.6056479018936,-0.0672262509964336,1.935377141239234
| 3,375
|
Microbody
| 19
| 55
| 2.209177
| 0.027162
|
O75521,P48735,Q9BQG2,P14735,Q9UKG9,Q8N4Q0,P51648,P04035,Q7Z434,Q96CN7,Q9BY49,P52758,P08670,Q15067,O15228,O75874,P50542,Q5T8D3,O14734
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
132,11,274,519,160,814,410,661,196,73,203,702,451,737,338,95,606,500,237
|
1068,897,898,237,338,1371,1491,2666,2108,132,95,2243,661,451,1771,1496,519,2118,1218,1908,2954,955,1569,1500,1081,11,606,410,1975,702,2495,3068,1719,737,2690,500,1599,3222,2931,196,814,1527,1667,2731,73,1296,274,1016,203,3093,2703,1249,822,160,1829
|
0.24689976348114367,0.358643578170959,0.358643578170959,1.1865840591524877,0.952569994453112,0.07685003800728503,0.019486354875994212,-0.5439512892731678,-0.24316559991811548,1.7400097763933111,2.031985358818018,-0.3025770869123972,0.5512660173470204,0.7938228645047847,-0.09631286647900751,0.019486354875994212,0.713579835070738,-0.24316559991811548,0.16225002844017103,-0.15476681385717422,-0.7910758719515134,0.33082515613705404,-0.009327790283860563,0.019486354875994212,0.24689976348114367,4.470238014994655,0.6056479018936,0.8469920138668321,-0.18413660636999382,0.5239685462529114,-0.42252790140681873,-0.948331973940958,-0.0672262509964336,0.49659904864423754,-0.5439512892731678,0.7403936172598823,-0.009327790283860563,-1.3995762482720377,-0.7598800080904538,1.3654085471612543,0.44164086630862914,0.019486354875994212,-0.038231613171792155,-0.5745330198140897,2.246862901123615,0.13386805297961285,1.1091068208502726,0.30292897251860446,1.340025485497747,-0.980035309228183,-0.5439512892731678,0.16225002844017103,0.44164086630862914,1.5665946676492313,-0.09631286647900751
| 3,375
|
Regulation of cell population proliferation
| 40
| 239
| 2.197243
| 0.028003
|
P00813,P49366,P12956,Q9UBL3,Q99538,Q15392,P43490,Q9BSK2,O14936,P30825,Q9HCL2,Q96DY7,P31751,Q12834,Q16512,Q96G23,P17931,Q9UIV1,P63167,Q32P28,P07384,P04439,O95630,O94788,O95140,O14757,O95684,P30536,P14174,P43307,Q9NQC3,Q14534,Q9Y4G8,Q9NRA0,O15360,Q96GN5,Q8IXJ6,P24941,Q15637,Q8WWQ0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,130,8,278,137,12,14,18,383,26,158,28,154,294,307,54,305,190,323,65,68,318,317,75,331,330,92,341,101,102,230,356,108,109,115,375,372,367,369,126
|
697,3160,580,2104,330,383,2294,796,115,1762,1553,1114,2824,1888,1763,1171,1764,1959,471,75,1261,331,2360,317,92,2670,2857,0,3079,3236,2825,3237,318,1322,948,2713,1174,1263,2486,1698,3099,68,582,1440,1628,2536,993,1899,2031,2302,633,8,1267,101,2829,2859,2788,1269,994,3060,1634,305,495,1841,1386,2186,1904,1387,520,367,2037,1566,2038,2189,665,2309,1909,341,26,154,1910,1178,2792,1179,2426,3026,1570,3211,756,1334,729,102,14,2793,2585,2251,2587,3046,130,605,3282,732,702,2495,1577,3358,541,759,2051,3257,1789,2130,3013,1791,323,998,1454,1648,3133,1792,761,1280,1510,2591,1048,872,2550,1187,2724,1229,2996,1797,1982,294,527,2725,2132,2899,673,873,2443,874,2327,2640,2901,807,808,2264,3344,1089,2803,1800,356,1393,2138,12,369,2928,307,1348,3365,65,767,3028,3317,1808,2339,544,2876,1196,964,2647,2603,372,707,840,738,2510,1666,2343,3271,2880,126,3363,442,1095,2075,2512,1012,2077,1531,1475,1936,28,1202,504,54,375,969,1817,1938,2153,2813,2276,137,3228,3137,783,2814,1205,18,2085,1820,3073,652,158,508,3151,230,3034,1207,2703,109,1880,2095,278,790,511,2740,190,1162,856,1252,1212,424,3181,108,984,3292
|
0.5239685462529114,-1.1719828815512887,0.6327337919013768,-0.24316559991811548,0.978809595175081,0.873480632258922,-0.33242471265450957,0.44164086630862914,1.862456329832627,-0.09631286647900751,-0.009327790283860563,0.21876491453847344,-0.6668117578076647,-0.15476681385717422,-0.09631286647900751,0.19054865591249434,-0.09631286647900751,-0.18413660636999382,0.7671410746721091,2.223153155757611,0.13386805297961285,0.978809595175081,-0.36236611826561227,1.004988400356168,2.0560289253619395,-0.5439512892731678,-0.6977474581428348,8.05927987366474,-0.980035309228183,-1.5313475075418816,-0.6668117578076647,-1.5313475075418816,1.004988400356168,0.10540172980990664,0.33082515613705404,-0.5745330198140897,0.19054865591249434,0.13386805297961285,-0.42252790140681873,-0.0672262509964336,-1.0118216311731156,2.294161378716793,0.6327337919013768,0.048211934796472365,-0.038231613171792155,-0.45274711809482365,0.30292897251860446,-0.15476681385717422,-0.21360297580762733,-0.33242471265450957,0.5784922208777676,4.85801582075318,0.13386805297961285,1.983768672818817,-0.6668117578076647,-0.6977474581428348,-0.6359637761900813,0.13386805297961285,0.30292897251860446,-0.948331973940958,-0.038231613171792155,1.031106974534266,0.7403936172598823,-0.1254926486793712,0.07685003800728503,-0.2728238448155597,-0.15476681385717422,0.07685003800728503,0.713579835070738,0.8999061013249092,-0.21360297580762733,-0.009327790283860563,-0.21360297580762733,-0.2728238448155597,0.5512660173470204,-0.33242471265450957,-0.15476681385717422,0.952569994453112,3.164753514554234,1.5665946676492313,-0.15476681385717422,0.19054865591249434,-0.6359637761900813,0.19054865591249434,-0.39240070950050854,-0.8851760478860837,-0.009327790283860563,-1.3668267524146023,0.4691567512932392,0.10540172980990664,0.49659904864423754,1.983768672818817,3.797869337859779,-0.6359637761900813,-0.4830577925150717,-0.3025770869123972,-0.4830577925150717,-0.9167120699523604,1.7645918959276166,0.6056479018936,-1.8322588413061764,0.49659904864423754,0.5239685462529114,-0.42252790140681873,-0.009327790283860563,-3.458357365309315,0.6866990592950521,0.4691567512932392,-0.21360297580762733,-1.6643385894420446,-0.09631286647900751,-0.24316559991811548,-0.8537243644783261,-0.09631286647900751,1.004988400356168,0.30292897251860446,0.048211934796472365,-0.038231613171792155,-1.075641485634037,-0.09631286647900751,0.4691567512932392,0.13386805297961285,0.019486354875994212,-0.4830577925150717,0.27495414250230754,0.38638510613707605,-0.45274711809482365,0.19054865591249434,-0.5745330198140897,0.16225002844017103,-0.82235748271142,-0.09631286647900751,-0.18413660636999382,1.057165873125376,0.713579835070738,-0.5745330198140897,-0.24316559991811548,-0.7287703736920425,0.5512660173470204,0.38638510613707605,-0.39240070950050854,0.38638510613707605,-0.33242471265450957,-0.5134593662434148,-0.7287703736920425,0.44164086630862914,0.44164086630862914,-0.3025770869123972,-2.734085777276208,0.24689976348114367,-0.6359637761900813,-0.09631286647900751,0.9262690243148245,0.07685003800728503,-0.24316559991811548,4.031896411144352,0.8999061013249092,-0.7598800080904538,1.031106974534266,0.10540172980990664,-4.017752483133644,2.341300334418682,0.4691567512932392,-0.8851760478860837,-2.104720346998251,-0.09631286647900751,-0.33242471265450957,0.6866990592950521,-0.6977474581428348,0.19054865591249434,0.33082515613705404,-0.5134593662434148,-0.4830577925150717,0.8999061013249092,0.5239685462529114,0.41405059073486755,0.49659904864423754,-0.42252790140681873,-0.038231613171792155,-0.33242471265450957,-1.7312845351077755,-0.6977474581428348,1.789127256491963,-3.7550283541650393,0.8204396326290617,0.24689976348114367,-0.21360297580762733,-0.42252790140681873,0.30292897251860446,-0.21360297580762733,0.019486354875994212,0.048211934796472365,-0.15476681385717422,3.1201613747468726,0.19054865591249434,0.7403936172598823,2.4817813149505383,0.8999061013249092,0.33082515613705404,-0.09631286647900751,-0.15476681385717422,-0.24316559991811548,-0.6359637761900813,-0.3025770869123972,1.6907038084850876,-1.4324034421386347,-1.075641485634037,0.4691567512932392,-0.6359637761900813,0.19054865591249434,3.6904267756578513,-0.21360297580762733,-0.09631286647900751,-0.948331973940958,0.5784922208777676,1.5665946676492313,0.7403936172598823,-1.1076741576662066,1.2379520800421246,-0.8851760478860837,0.19054865591249434,-0.5439512892731678,1.935377141239234,-0.1254926486793712,-0.21360297580762733,1.1091068208502726,0.4691567512932392,0.7403936172598823,-0.5745330198140897,1.39073841091754,0.21876491453847344,0.41405059073486755,0.16225002844017103,0.19054865591249434,0.8469920138668321,-1.2042581055902233,1.9595949228824863,0.33082515613705404,-1.8660637299899208
| 3,375
|
Tetratricopeptide-like helical domain superfamily [IPR011990]
| 23
| 91
| 2.186074
| 0.02881
|
O75153,O00170,Q7Z4L5,Q8IWR0,Q6DKK2,Q7L5D6,Q86UA1,Q92791,Q9UBV2,Q32P28,Q9Y262,O15460,P13674,O75718,Q96EK5,Q9UJX3,Q96BR5,Q9H0B6,Q13217,O00411,A0AVF1,Q9Y6X3,O15091
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
6,512,156,415,165,184,438,56,198,65,597,74,76,78,351,486,619,360,477,354,353,112,364
|
353,512,986,354,1256,364,1372,74,1551,1375,2484,6,78,2110,2786,1891,2921,1033,76,1124,2310,1178,1846,1640,2314,1130,606,2126,2757,637,1793,1390,1511,1188,1797,2441,477,2963,1392,2136,2444,3120,2445,2689,2966,65,3351,1864,165,2394,3253,2560,1809,1232,184,156,438,415,1010,56,3088,619,1816,351,1099,2273,1243,1296,1872,1873,2655,2816,360,1412,2088,1741,3319,1414,2517,2914,198,1311,486,1364,3241,2014,597,1954,1547,1111,112
|
0.9262690243148245,0.713579835070738,0.30292897251860446,0.9262690243148245,0.13386805297961285,0.8999061013249092,0.07685003800728503,2.223153155757611,-0.009327790283860563,0.07685003800728503,-0.42252790140681873,5.078968659420913,2.199402700232554,-0.24316559991811548,-0.6359637761900813,-0.15476681385717422,-0.7598800080904538,0.27495414250230754,2.223153155757611,0.21876491453847344,-0.33242471265450957,0.19054865591249434,-0.1254926486793712,-0.038231613171792155,-0.33242471265450957,0.21876491453847344,0.6056479018936,-0.24316559991811548,-0.6052040240979027,0.5784922208777676,-0.09631286647900751,0.07685003800728503,0.019486354875994212,0.19054865591249434,-0.09631286647900751,-0.39240070950050854,0.7671410746721091,-0.7910758719515134,0.07685003800728503,-0.24316559991811548,-0.39240070950050854,-1.04369050099163,-0.39240070950050854,-0.5439512892731678,-0.7910758719515134,2.341300334418682,-2.9846825238616717,-0.1254926486793712,1.516605184692839,-0.36236611826561227,-1.6309777012387325,-0.45274711809482365,-0.09631286647900751,0.16225002844017103,1.416015523904057,1.5665946676492313,0.8204396326290617,0.8469920138668321,0.30292897251860446,2.4584637978137454,-0.980035309228183,0.6056479018936,-0.09631286647900751,0.952569994453112,0.24689976348114367,-0.3025770869123972,0.16225002844017103,0.13386805297961285,-0.1254926486793712,-0.1254926486793712,-0.5134593662434148,-0.6359637761900813,0.9262690243148245,0.07685003800728503,-0.21360297580762733,-0.0672262509964336,-2.104720346998251,0.07685003800728503,-0.42252790140681873,-0.7287703736920425,1.3654085471612543,0.13386805297961285,0.7671410746721091,0.10540172980990664,-1.5313475075418816,-0.18413660636999382,0.6327337919013768,-0.15476681385717422,0.019486354875994212,0.24689976348114367,1.9111150023933372
| 3,375
|
Abnormality of thyroid physiology
| 20
| 79
| 2.182219
| 0.029093
|
P00813,Q13423,O00170,P27635,P12235,Q92890,P03886,Q9Y3Z3,O00192,O95155,Q92766,Q07021,Q9BUK6,P61978,Q96RR1,O43683,Q15056,P53992,P00403,Q8WWQ0
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,262,512,635,143,150,31,692,537,42,442,671,79,345,219,470,233,608,494,126
|
512,537,897,795,1369,1257,470,1837,945,1378,2109,2110,42,1766,494,0,31,1769,2031,143,2716,1078,635,2194,1179,2676,1332,3211,1334,1084,608,1575,1275,1578,345,2637,2261,671,1982,835,262,1654,809,2134,1984,2446,233,2872,1928,1135,1809,2730,2343,126,442,150,778,1402,2270,1098,2273,1817,219,1242,79,2817,3210,1821,2777,1881,2470,3241,720,1163,2982,2169,692,1253,3292
|
0.713579835070738,0.6866990592950521,0.358643578170959,0.44164086630862914,0.07685003800728503,0.13386805297961285,0.7671410746721091,-0.1254926486793712,0.33082515613705404,0.07685003800728503,-0.24316559991811548,-0.24316559991811548,2.7129169777181765,-0.09631286647900751,0.7403936172598823,8.05927987366474,3.030593559630485,-0.09631286647900751,-0.21360297580762733,1.6412063989989234,-0.5745330198140897,0.24689976348114367,0.5784922208777676,-0.2728238448155597,0.19054865591249434,-0.5439512892731678,0.10540172980990664,-1.3668267524146023,0.10540172980990664,0.24689976348114367,0.6056479018936,-0.009327790283860563,0.13386805297961285,-0.009327790283860563,0.952569994453112,-0.5134593662434148,-0.3025770869123972,0.5512660173470204,-0.18413660636999382,0.41405059073486755,1.1349899370587961,-0.038231613171792155,0.44164086630862914,-0.24316559991811548,-0.18413660636999382,-0.39240070950050854,1.212296082730813,-0.6977474581428348,-0.15476681385717422,0.21876491453847344,-0.09631286647900751,-0.5745330198140897,-0.33242471265450957,1.789127256491963,0.8204396326290617,1.6163849582577512,0.4691567512932392,0.07685003800728503,-0.3025770869123972,0.24689976348114367,-0.3025770869123972,-0.09631286647900751,1.2635525405656844,0.16225002844017103,2.199402700232554,-0.6359637761900813,-1.334155331699041,-0.09631286647900751,-0.6052040240979027,-0.1254926486793712,-0.39240070950050854,-1.5313475075418816,0.5239685462529114,0.21876491453847344,-0.7910758719515134,-0.24316559991811548,0.5512660173470204,0.16225002844017103,-1.8660637299899208
| 3,375
|
Dry skin
| 7
| 29
| 2.176848
| 0.029492
|
P00813,Q9Y3Z3,P51648,Q08J23,P11802,Q2TAA5,P37268
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,692,410,41,633,309,521
|
2109,0,1769,1439,633,1565,3080,1702,2308,2309,1500,521,1332,410,1085,1275,872,1715,41,2872,1593,309,1809,815,2081,1242,743,2518,692
|
-0.24316559991811548,8.05927987366474,-0.09631286647900751,0.048211934796472365,0.5784922208777676,-0.009327790283860563,-0.980035309228183,-0.0672262509964336,-0.33242471265450957,-0.33242471265450957,0.019486354875994212,0.713579835070738,0.10540172980990664,0.8469920138668321,0.24689976348114367,0.13386805297961285,0.38638510613707605,-0.0672262509964336,2.7358317422764893,-0.6977474581428348,-0.009327790283860563,1.031106974534266,-0.09631286647900751,0.44164086630862914,-0.21360297580762733,0.16225002844017103,0.49659904864423754,-0.42252790140681873,0.5512660173470204
| 3,375
|
Fatty acid metabolism
| 11
| 52
| 2.17511
| 0.029622
|
P11310,P23786,P42126,O15121,P51648,Q9BY49,Q16836,O14734,P30084,P50416,Q9UKG9
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
1,34,408,38,410,203,15,237,204,266,160
|
428,1316,1687,2237,237,38,1371,2108,753,990,2243,1768,1771,1,34,2368,1446,204,955,2122,408,1571,1040,1041,2756,266,410,1975,2127,2758,3068,1716,673,2505,737,2766,15,3347,2267,2931,3239,2602,3279,1528,2974,203,572,1683,1544,822,160,2823
|
0.8204396326290617,0.10540172980990664,-0.0672262509964336,-0.3025770869123972,1.1865840591524877,2.8043654472386006,0.07685003800728503,-0.24316559991811548,0.4691567512932392,0.30292897251860446,-0.3025770869123972,-0.09631286647900751,-0.09631286647900751,7.367385577094042,2.985614892363513,-0.36236611826561227,0.048211934796472365,1.3145887721057432,0.33082515613705404,-0.24316559991811548,0.8469920138668321,-0.009327790283860563,0.27495414250230754,0.27495414250230754,-0.6052040240979027,1.1091068208502726,0.8469920138668321,-0.18413660636999382,-0.24316559991811548,-0.6052040240979027,-0.948331973940958,-0.0672262509964336,0.5512660173470204,-0.42252790140681873,0.49659904864423754,-0.6052040240979027,3.797869337859779,-2.7696897938215086,-0.3025770869123972,-0.7598800080904538,-1.5313475075418816,-0.4830577925150717,-1.7985271289035507,0.019486354875994212,-0.7910758719515134,1.340025485497747,0.6597506092154378,-0.038231613171792155,0.019486354875994212,0.44164086630862914,1.5665946676492313,-0.6359637761900813
| 3,375
|
Phosphatase activity
| 12
| 57
| 2.171628
| 0.029884
|
Q9UNI6,P49902,Q08623,Q9NPH0,Q99504,Q9BRF8,Q13555,Q9H857,Q9NX62,Q9ULE6,Q86UY8,Q96PE3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
402,343,162,2,229,39,355,445,215,225,122,94
|
1367,3021,1689,2112,1627,2179,3306,1701,1038,1567,3061,343,2316,2126,1575,866,2836,2377,526,2898,2056,1049,162,999,2132,355,1924,2597,3147,437,838,1993,122,3259,3071,2566,617,1355,2883,94,229,1673,39,1302,2657,2405,1614,445,846,1742,1679,2,2007,2283,215,225,402
|
0.07685003800728503,-0.8851760478860837,-0.0672262509964336,-0.24316559991811548,-0.038231613171792155,-0.2728238448155597,-2.036174700270587,-0.0672262509964336,0.27495414250230754,-0.009327790283860563,-0.948331973940958,0.952569994453112,-0.33242471265450957,-0.24316559991811548,-0.009327790283860563,0.38638510613707605,-0.6668117578076647,-0.36236611826561227,0.713579835070738,-0.7287703736920425,-0.21360297580762733,0.27495414250230754,1.516605184692839,0.30292897251860446,-0.24316559991811548,0.9262690243148245,-0.15476681385717422,-0.4830577925150717,-1.1076741576662066,0.8204396326290617,0.41405059073486755,-0.18413660636999382,1.8136162149972994,-1.6643385894420446,-0.948331973940958,-0.45274711809482365,0.6056479018936,0.10540172980990664,-0.6977474581428348,2.0560289253619395,1.2379520800421246,-0.038231613171792155,2.7815557604620307,0.13386805297961285,-0.5134593662434148,-0.36236611826561227,-0.009327790283860563,0.8204396326290617,0.41405059073486755,-0.0672262509964336,-0.038231613171792155,6.8766404995232415,-0.18413660636999382,-0.3025770869123972,1.2890979463364292,1.2635525405656844,0.873480632258922
| 3,375
|
Acne
| 6
| 13
| 2.171588
| 0.029887
|
O00192,Q9NZ08,O00170,Q92766,Q92890,Q9H488
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
537,103,512,442,150,121
|
512,537,1634,2364,1078,1041,608,2345,442,150,121,103,1830
|
0.713579835070738,0.6866990592950521,-0.038231613171792155,-0.36236611826561227,0.24689976348114367,0.27495414250230754,0.6056479018936,-0.33242471265450957,0.8204396326290617,1.6163849582577512,1.8380591236082113,1.983768672818817,-0.09631286647900751
| 3,375
|
Kinase activity
| 47
| 146
| 2.169475
| 0.030047
|
Q13546,P11802,P41240,O14936,Q4G0N4,Q53H12,Q9NVE7,Q9UHD2,P31751,P49841,Q9Y5P4,Q6P3W7,Q14012,P04183,P27144,Q16512,O00443,O15164,Q99640,Q00013,Q15418,Q13131,P49840,Q9Y223,Q9UDY2,Q14168,Q9Y3D8,P46020,O14976,P55263,O14578,O14757,Q13572,Q9BVS4,Q15120,Q9UBF8,Q8NI60,O43252,Q8WVC6,O43683,Q13464,Q9HA64,Q13555,Q9NRA0,Q9BRR6,P24941,P51812
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
528,633,756,383,23,768,289,689,154,32,694,677,810,801,664,307,795,796,444,670,53,673,805,720,199,325,329,192,191,193,579,330,585,742,90,747,93,469,615,470,104,236,355,109,118,367,239
|
795,1429,579,330,383,191,796,469,2984,470,1378,1116,2577,1320,2668,900,2670,2244,1961,801,1698,1561,1631,2858,3192,633,1441,904,3041,1773,2788,1634,2364,1077,1217,1386,1498,1445,2186,1176,367,2491,664,2189,1777,2309,2861,154,1178,3116,1500,756,1846,192,995,805,32,2254,3250,2048,239,917,958,2127,2318,1576,193,2376,998,1454,1648,670,1280,1047,2055,872,2550,1979,1088,2132,2899,2442,673,873,2764,2900,1799,807,104,1853,2927,528,355,585,810,325,3104,90,2690,2139,53,307,1859,1348,3167,23,768,1461,2392,677,2454,1664,1396,2562,3264,93,967,615,2001,2272,1013,1476,1940,444,2514,118,1409,742,2656,1153,2351,236,109,289,3324,2408,747,199,689,1825,1881,720,329,2101,1955,694
|
0.44164086630862914,0.048211934796472365,0.6327337919013768,0.978809595175081,0.873480632258922,1.3654085471612543,0.44164086630862914,0.7671410746721091,-0.82235748271142,0.7671410746721091,0.07685003800728503,0.21876491453847344,-0.4830577925150717,0.10540172980990664,-0.5439512892731678,0.358643578170959,-0.5439512892731678,-0.3025770869123972,-0.18413660636999382,0.44164086630862914,-0.0672262509964336,-0.009327790283860563,-0.038231613171792155,-0.6977474581428348,-1.2690482472817965,0.5784922208777676,0.048211934796472365,0.358643578170959,-0.9167120699523604,-0.09631286647900751,-0.6359637761900813,-0.038231613171792155,-0.36236611826561227,0.24689976348114367,0.16225002844017103,0.07685003800728503,0.019486354875994212,0.048211934796472365,-0.2728238448155597,0.19054865591249434,0.8999061013249092,-0.42252790140681873,0.5512660173470204,-0.2728238448155597,-0.09631286647900751,-0.33242471265450957,-0.6977474581428348,1.5665946676492313,0.19054865591249434,-1.04369050099163,0.019486354875994212,0.4691567512932392,-0.1254926486793712,1.3654085471612543,0.30292897251860446,0.44164086630862914,3.030593559630485,-0.3025770869123972,-1.5976919926421527,-0.21360297580762733,1.1865840591524877,0.358643578170959,0.33082515613705404,-0.24316559991811548,-0.33242471265450957,-0.009327790283860563,1.3654085471612543,-0.36236611826561227,0.30292897251860446,0.048211934796472365,-0.038231613171792155,0.5512660173470204,0.13386805297961285,0.27495414250230754,-0.21360297580762733,0.38638510613707605,-0.45274711809482365,-0.18413660636999382,0.24689976348114367,-0.24316559991811548,-0.7287703736920425,-0.39240070950050854,0.5512660173470204,0.38638510613707605,-0.6052040240979027,-0.7287703736920425,-0.09631286647900751,0.44164086630862914,1.9595949228824863,-0.1254926486793712,-0.7598800080904538,0.713579835070738,0.9262690243148245,0.6327337919013768,0.44164086630862914,1.004988400356168,-1.0118216311731156,2.0800297213070706,-0.5439512892731678,-0.24316559991811548,2.4817813149505383,1.031106974534266,-0.1254926486793712,0.10540172980990664,-1.1719828815512887,3.4077973078556516,0.4691567512932392,0.048211934796472365,-0.36236611826561227,0.5512660173470204,-0.39240070950050854,-0.038231613171792155,0.07685003800728503,-0.45274711809482365,-1.6977743138917556,2.0560289253619395,0.33082515613705404,0.6056479018936,-0.18413660636999382,-0.3025770869123972,0.30292897251860446,0.048211934796472365,-0.15476681385717422,0.8204396326290617,-0.42252790140681873,1.862456329832627,0.07685003800728503,0.49659904864423754,-0.5134593662434148,0.21876491453847344,-0.33242471265450957,1.212296082730813,1.935377141239234,1.0831656426328216,-2.1390993722008798,-0.36236611826561227,0.49659904864423754,1.3654085471612543,0.5512660173470204,-0.09631286647900751,-0.1254926486793712,0.5239685462529114,1.004988400356168,-0.21360297580762733,-0.15476681385717422,0.5512660173470204
| 3,375
|
Peroxisomal protein import
| 10
| 21
| 2.162173
| 0.030605
|
O75521,Q9BY49,P50542,O14734,O15228,Q15067,Q93008,P14735,Q9UKG9,O75874
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
132,203,606,237,338,737,778,519,160,95
|
1068,237,338,1371,2666,132,95,1771,519,2118,1569,606,1975,3068,737,778,1016,203,822,160,1829
|
0.24689976348114367,1.1865840591524877,0.952569994453112,0.07685003800728503,-0.5439512892731678,1.7400097763933111,2.031985358818018,-0.09631286647900751,0.713579835070738,-0.24316559991811548,-0.009327790283860563,0.6056479018936,-0.18413660636999382,-0.948331973940958,0.49659904864423754,0.4691567512932392,0.30292897251860446,1.340025485497747,0.44164086630862914,1.5665946676492313,-0.09631286647900751
| 3,375
|
Nucleoside phosphate biosynthetic process
| 12
| 99
| 2.155401
| 0.03113
|
P00813,P53007,P00846,P55263,O95563,Q9NRA0,Q9BQG2,P43490,Q8NFF5,Q4G0N4,Q9NVE7,Q15120
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,227,260,193,302,109,274,14,272,23,289,90
|
1316,697,1687,1432,469,1259,2108,1693,3126,698,302,2243,494,2857,1839,1961,0,260,1697,801,1493,1073,2361,1560,3142,1326,2301,2114,2828,1772,1965,1441,1496,2788,905,2184,1079,2185,2186,1176,583,1177,2368,2037,664,1777,2861,1080,1843,1220,2039,955,1126,2955,407,1844,1448,1705,14,3045,913,2494,2864,227,1976,2318,1786,193,1086,2681,2376,2799,1979,1186,2442,1716,674,2446,3104,90,23,3347,2599,272,2343,546,615,2076,2001,274,2656,109,744,289,1683,1750,1485,1546,329
|
0.10540172980990664,0.5239685462529114,-0.0672262509964336,0.048211934796472365,0.7671410746721091,0.13386805297961285,-0.24316559991811548,-0.0672262509964336,-1.075641485634037,0.5239685462529114,1.031106974534266,-0.3025770869123972,0.7403936172598823,-0.6977474581428348,-0.1254926486793712,-0.18413660636999382,8.05927987366474,1.1349899370587961,-0.0672262509964336,0.44164086630862914,0.019486354875994212,0.24689976348114367,-0.36236611826561227,-0.009327790283860563,-1.1076741576662066,0.10540172980990664,-0.33242471265450957,-0.24316559991811548,-0.6668117578076647,-0.09631286647900751,-0.18413660636999382,0.048211934796472365,0.019486354875994212,-0.6359637761900813,0.358643578170959,-0.2728238448155597,0.24689976348114367,-0.2728238448155597,-0.2728238448155597,0.19054865591249434,0.6327337919013768,0.19054865591249434,-0.36236611826561227,-0.21360297580762733,0.5512660173470204,-0.09631286647900751,-0.6977474581428348,0.24689976348114367,-0.1254926486793712,0.16225002844017103,-0.21360297580762733,0.33082515613705404,0.21876491453847344,-0.7910758719515134,0.8469920138668321,-0.1254926486793712,0.048211934796472365,-0.0672262509964336,3.797869337859779,-0.9167120699523604,0.358643578170959,-0.42252790140681873,-0.6977474581428348,1.2379520800421246,-0.18413660636999382,-0.33242471265450957,-0.09631286647900751,1.3654085471612543,0.24689976348114367,-0.5439512892731678,-0.36236611826561227,-0.6359637761900813,-0.18413660636999382,0.19054865591249434,-0.39240070950050854,-0.0672262509964336,0.5512660173470204,-0.39240070950050854,-1.0118216311731156,2.0800297213070706,3.4077973078556516,-2.7696897938215086,-0.4830577925150717,1.1091068208502726,-0.33242471265450957,0.6866990592950521,0.6056479018936,-0.21360297580762733,-0.18413660636999382,1.1091068208502726,-0.5134593662434148,1.935377141239234,0.49659904864423754,1.0831656426328216,-0.038231613171792155,-0.0672262509964336,0.048211934796472365,0.019486354875994212,1.004988400356168
| 3,375
|
Subsets and Splits
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