term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Negative regulation of defense response
12
34
2.14841
0.031681
P00813,Q9Y3Z3,P04439,Q86UT6,O43657,Q7Z739,Q8IXJ6,Q92890,P28070,Q9Y4E8,Q9UIV1,Q96BN8
Processes and pathways
GO Biological process
msigdb_gobp
0,692,318,241,384,501,372,150,556,425,190,417
384,3039,0,1962,318,2486,1631,1841,907,2424,556,3174,1127,1275,671,1854,1518,1348,3167,501,2396,241,372,2694,150,417,1817,1013,1606,3094,190,692,425,895
0.873480632258922,-0.9167120699523604,8.05927987366474,-0.18413660636999382,1.004988400356168,-0.42252790140681873,-0.038231613171792155,-0.1254926486793712,0.358643578170959,-0.39240070950050854,0.6597506092154378,-1.2042581055902233,0.21876491453847344,0.13386805297961285,0.5512660173470204,-0.1254926486793712,0.0194...
3,375
Abnormality of the tonsils
6
9
2.137725
0.032539
P00813,Q13546,O00192,Q92766,Q92890,P31751
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,528,537,442,150,154
537,0,1078,154,608,2721,528,442,150
0.6866990592950521,8.05927987366474,0.24689976348114367,1.5665946676492313,0.6056479018936,-0.5745330198140897,0.713579835070738,0.8204396326290617,1.6163849582577512
3,375
Dyskinesia
16
72
2.134768
0.03278
Q9UBX3,Q9H2C2,Q9BPX6,P35610,P00846,Q08J23,Q9NUQ7,Q9Y4P8,Q9NYY8,O43819,Q6PML9,O14936,Q96RL7,Q99497,Q9UBB6,P03886
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
400,66,465,407,260,41,575,251,379,385,270,383,51,20,549,31
1428,383,3231,385,2415,2240,581,1171,3200,260,31,1962,1900,2304,2368,407,1448,1640,865,2375,1708,2201,1042,2128,868,3047,998,1510,1793,1794,1650,1795,1049,41,1652,2725,1655,3205,1803,2140,2141,270,2908,1664,2459,1869,968,1098,740,2461,1938,1151,1606,51,20,465,1102,2226,2158,66,1479,575,379,1683,2096,1419,549,400,1108,1...
0.048211934796472365,0.873480632258922,-1.4653079613874214,0.873480632258922,-0.39240070950050854,-0.3025770869123972,0.6327337919013768,0.19054865591249434,-1.334155331699041,1.1349899370587961,3.030593559630485,-0.18413660636999382,-0.15476681385717422,-0.33242471265450957,-0.36236611826561227,0.8469920138668321,0.04...
3,375
Limitation of joint mobility
20
104
2.119191
0.034074
Q04446,Q969X5,P48735,Q03001,O00469,P23786,P51648,O95155,Q9H2M9,O15460,Q6KC79,O95140,Q8WVM7,O75874,O75844,Q15056,O14979,Q9BT22,Q15427,Q96AY3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
261,135,11,17,280,34,410,42,466,74,456,331,350,95,471,233,110,376,497,124
795,280,3112,2945,110,74,2984,1554,859,1116,2667,1691,2297,3039,471,95,2110,3198,2298,331,42,3079,2487,632,1440,2302,1442,3243,994,3080,2247,1776,34,2309,2311,1179,2676,521,1705,2200,11,605,3282,410,1451,1576,1786,2637,2898,1455,17,261,1583,2056,1652,1982,835,1283,1133,1090,1984,3103,2138,1590,233,497,456,1727,2269,152...
0.44164086630862914,1.0831656426328216,-1.04369050099163,-0.7910758719515134,1.9111150023933372,2.223153155757611,-0.82235748271142,-0.009327790283860563,0.38638510613707605,0.21876491453847344,-0.5439512892731678,-0.0672262509964336,-0.33242471265450957,-0.9167120699523604,0.7671410746721091,2.031985358818018,-0.24316...
3,375
Positive regulation of cell growth
10
36
2.113833
0.03453
P78344,P51812,Q6PJG6,P58546,Q9BSK2,Q15418,Q7L576,Q9Y3B8,O95684,Q96K76
Processes and pathways
GO Biological process
msigdb_gobp
194,239,201,454,18,53,479,424,92,63
3160,1428,2709,1435,92,2752,1707,912,239,2496,454,2051,3257,194,1650,1796,1980,2134,53,1520,3086,201,479,2457,2268,63,18,2889,2890,2286,1107,2470,487,1163,424,1067
-1.1719828815512887,0.048211934796472365,-0.5745330198140897,0.048211934796472365,2.0560289253619395,-0.6052040240979027,-0.0672262509964336,0.358643578170959,1.1865840591524877,-0.42252790140681873,0.7938228645047847,-0.21360297580762733,-1.6643385894420446,1.3654085471612543,-0.038231613171792155,-0.09631286647900751...
3,375
Cation transport
40
163
2.103013
0.035465
Q13423,P00846,Q9HC07,Q96GC9,P12235,Q6PML9,O14936,Q99497,Q9HD20,Q8N668,P30825,Q8WWC4,P31930,O43772,P46939,P61421,Q9Y4W6,Q6YHU6,Q9UI12,P42858,Q6KCM7,P17931,Q70HW3,P07384,O43865,Q9BPX6,Q8N4V1,P30536,P24941,P54652,P46934,O75844,Q6P4Q7,Q13555,Q8IYU8,Q9NRA0,P20337,P00403,P08195,O15173
Processes and pathways
GO Biological process
msigdb_gobp
262,260,139,136,143,270,383,20,151,285,26,286,539,33,540,293,578,413,447,175,311,305,188,68,69,465,81,341,367,476,473,471,357,355,502,109,119,494,252,489
858,722,897,2103,3096,2104,383,489,1626,33,1491,69,1556,946,1690,629,947,471,3126,698,2110,2029,2670,494,260,3236,948,2179,2628,2713,1174,1263,1073,2580,68,1964,252,1265,1495,1564,2032,1120,143,2986,1633,1037,1634,2364,305,1841,1444,119,827,2716,1123,2247,700,1177,367,2037,2834,2190,557,2674,341,1330,26,539,863,1179,32...
0.38638510613707605,0.49659904864423754,0.358643578170959,-0.24316559991811548,-1.0118216311731156,-0.24316559991811548,0.873480632258922,0.7403936172598823,-0.038231613171792155,3.0081206146023467,0.019486354875994212,2.2705322165054698,-0.009327790283860563,0.33082515613705404,-0.0672262509964336,0.5784922208777676,0...
3,375
Abnormality of the metaphysis
9
59
2.098
0.035905
P00813,Q9HC07,P48735,Q13126,Q9H9E3,Q14999,Q9NSE4,O75874,Q7Z4L5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,139,11,43,107,149,222,95,156
795,2984,2108,3114,95,3198,2669,449,0,1322,2486,3099,1264,3243,2246,2247,2833,667,2252,2200,11,606,1183,2203,2898,268,2056,834,43,1459,3103,149,2138,2727,639,156,1295,3349,1402,816,2273,969,2734,886,1410,3033,3210,1876,107,139,1616,2979,222,575,2009,2660,1623,1953,2411
0.44164086630862914,-0.82235748271142,-0.24316559991811548,-1.04369050099163,2.031985358818018,-1.334155331699041,-0.5439512892731678,0.7938228645047847,8.05927987366474,0.10540172980990664,-0.42252790140681873,-1.0118216311731156,0.13386805297961285,-1.5644818109642689,-0.3025770869123972,-0.3025770869123972,-0.666811...
3,375
Membrane protein proteolysis
6
11
2.087195
0.03687
Q9NZ08,Q13464,Q16740,Q9Y4W6,O43847,Q8TCT9
Processes and pathways
GO Biological process
msigdb_gobp
103,104,9,578,386,564
386,2040,558,104,9,564,2345,103,2941,578,2525
0.873480632258922,-0.21360297580762733,0.6597506092154378,1.9595949228824863,4.511437534011964,0.6597506092154378,-0.33242471265450957,1.983768672818817,-0.7598800080904538,0.6597506092154378,-0.42252790140681873
3,375
Mania
8
15
2.085991
0.036979
Q96RR1,O00192,P51812,P12235,Q92766,Q92890,P00403,P03886
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
219,537,239,143,442,150,494,31
537,494,31,143,1037,1078,3282,239,608,1575,442,150,219,1303,1750
0.6866990592950521,0.7403936172598823,3.030593559630485,1.6412063989989234,0.27495414250230754,0.24689976348114367,-1.8322588413061764,1.1865840591524877,0.6056479018936,-0.009327790283860563,0.8204396326290617,1.6163849582577512,1.2635525405656844,0.13386805297961285,-0.0672262509964336
3,375
Abnormality of the thyroid gland
12
109
2.084926
0.037076
P00813,Q96RR1,O95155,P48735,Q15056,Q9BUK6,P12235,Q92890,Q14145,Q8WWQ0,O75874,P03886
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,219,42,11,233,79,143,150,182,126,95,31
512,537,897,795,1550,1369,1257,1761,470,1837,945,1378,2109,95,2110,42,1766,1173,494,0,3079,31,1769,1322,2031,143,1903,2716,1329,1078,635,2194,1179,2676,1332,3211,1334,1912,865,11,1041,1084,2125,1042,608,1575,1275,1578,868,345,2637,2261,671,1982,2899,835,262,1654,2800,809,2134,182,1133,1984,2446,233,3165,2872,1928,1987,...
0.713579835070738,0.6866990592950521,0.358643578170959,0.44164086630862914,-0.009327790283860563,0.07685003800728503,0.13386805297961285,-0.09631286647900751,0.7671410746721091,-0.1254926486793712,0.33082515613705404,0.07685003800728503,-0.24316559991811548,2.031985358818018,-0.24316559991811548,2.7129169777181765,-0.0...
3,375
Endoplasmic reticulum
172
494
7.020447
0
O43681,P10321,P80303,Q15363,O76024,Q5J8M3,Q9H497,P67812,P09601,Q8N4V1,Q13555,Q86SK9,A1L0T0,Q96AY3,Q9P2W9,O95197,P30519,P43307,Q01105,Q14108,Q8N511,O15260,Q9H6V9,Q15629,Q9H2C2,Q9NTJ5,Q9Y3B3,Q14849,Q9UNK0,O75718,Q15041,P49069,Q8TC12,P10619,Q4ZIN3,O15173,Q8TCD1,Q7Z2K6,Q5BJF2,Q9H0U4,Q8IV08,Q6PML9,O43464,O75844,Q9BRR6,P0406...
Localization
GO Cellular component
msigdb_gocc
506,509,4,5,507,519,523,13,15,19,528,530,524,549,29,30,33,34,546,37,40,39,45,50,53,572,57,58,575,568,570,569,583,68,70,72,75,595,77,599,81,594,590,88,91,90,92,615,96,97,98,602,625,106,109,620,111,116,119,638,123,643,126,127,630,628,626,134,135,137,141,143,144,146,148,149,150,157,159,163,165,167,173,174,178,189,191,192,...
1661,524,602,277,826,1436,446,252,1370,1737,657,297,1326,626,1867,1919,627,157,123,72,914,39,491,1868,3310,807,1740,1572,841,2884,590,3196,506,472,386,1063,738,1741,126,1668,1669,1088,366,2303,2131,1217,137,1791,568,770,88,454,507,2753,1922,1700,2831,1794,2679,1514,204,30,2050,294,1516,265,2221,2482,1873,2718,2603,1403...
-0.10377915671823269,0.7490655969974919,0.6500364914113959,1.322192093055503,0.4085574264207841,0.015900464346774338,0.8929413902574874,1.4050887812930244,0.055014368762545285,-0.14447423395217424,0.5825675708995396,1.2373723709299225,0.07442888489169129,0.6164499083295459,-0.20629282062173515,-0.22710959688583782,0.61...
3,376
Organelle subcompartment
146
398
5.074453
0
P10321,O15126,O76024,Q15363,Q5J8M3,Q96ED9,Q8NBN3,P67812,Q9NPR9,P09601,Q8N4V1,Q13555,Q86SK9,P35670,A1L0T0,Q9P2W9,O95197,P40616,P30519,P43307,Q14108,Q8N511,O15260,O60499,P11717,Q15629,Q9H2C2,Q9NTJ5,Q9Y3B3,Q14849,Q9UNK0,Q15041,P49069,Q8TC12,Q4ZIN3,Q7Z2K6,Q5BJF2,O00461,Q8IV08,Q9H0U4,O43464,O75844,Q9BRR6,P04062,Q86XL3,Q9Y3A...
Localization
GO Cellular component
msigdb_gocc
509,505,507,5,519,522,12,13,14,15,19,528,530,526,524,29,30,544,33,34,37,40,39,41,542,50,53,572,57,58,575,570,569,583,70,595,77,80,81,599,590,88,91,90,92,615,96,97,98,106,109,112,116,119,123,126,127,134,135,141,143,144,146,148,149,165,167,173,174,178,191,192,200,201,202,204,208,213,221,224,228,229,235,237,241,249,250,25...
1661,524,277,826,2257,80,1436,446,1370,1737,2180,657,1326,626,1619,1867,1919,627,123,505,885,39,491,1868,1572,2884,590,1920,200,3080,472,386,1063,41,1741,126,1668,1669,1622,366,2303,2131,1217,770,88,454,507,1700,2831,1794,2679,1514,204,30,201,2050,724,265,2221,2482,1873,2603,1404,261,90,273,791,2483,143,1119,134,2887,1...
-0.10377915671823269,0.7490655969974919,1.322192093055503,0.4085574264207841,-0.3975717877794668,2.5693783360444082,0.015900464346774338,0.8929413902574874,0.055014368762545285,-0.14447423395217424,-0.354287776657499,0.5825675708995396,0.07442888489169129,0.6164499083295459,-0.0835841298387108,-0.20629282062173515,-0.2...
3,376
Vacuolar lumen
27
63
4.793875
0.000002
P06865,P08236,P38435,P50897,O14773,P04066,Q14108,Q9UM22,P10253,P06280,Q99538,Q9NZJ7,O00560,Q9UMR5,P10619,P11117,P15586,Q8IV08,Q9BRF8,P07602,P04062,P16278,P17900,Q8NHP8,Q13510,P54802,O00584
Localization
GO Cellular component
msigdb_gocc
262,381,148,22,25,291,37,43,182,310,184,444,446,66,68,197,319,81,209,333,90,93,353,108,111,121,252
446,252,790,25,506,1404,90,291,310,262,2786,792,333,1185,1092,381,182,68,197,2136,1551,319,93,353,2089,1974,2519,148,2922,1835,1522,22,1634,1802,1887,121,2148,1838,812,892,992,2151,1716,111,37,2615,81,2421,108,785,1018,2168,551,184,209,855,1650,459,2176,444,43,66,1962
0.8929413902574874,1.4050887812930244,0.4439885391534624,3.190224570239214,0.7815125855528189,0.03550516234149863,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,-0.6905032048336213,0.4439885391534624,1.135880610204166,0.15115574181980668,0.2077445134366247,1.0315318217278158,1.76858811774524...
3,376
Membrane lipid metabolic process
24
41
4.597288
0.000004
P06865,O95470,P30153,P50897,P04066,Q8NBX0,Q96G23,Q9H2C2,Q99735,P06280,Q9NZJ7,Q16739,Q99805,Q9NZD2,P07602,Q8NCC3,Q9P035,P04062,P16278,P17900,Q06136,Q9NRA0,Q13510,O15121
Processes and pathways
GO Biological process
msigdb_gobp
262,265,268,22,291,166,167,53,437,310,444,64,196,210,333,85,481,90,93,353,98,489,111,123
123,491,1868,590,1668,265,90,291,310,262,333,1185,93,353,1750,268,22,98,1303,111,64,744,166,85,1273,1355,167,934,437,196,53,878,489,2120,1173,1464,210,444,481,2435,825
2.1428207883227306,0.8136850803085195,-0.20629282062173515,0.6667202646970376,-0.10377915671823269,1.3638760848112592,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,1.135880610204166,0.15115574181980668,2.470216891564265,1.1063642295621396,-0.14447423395217424,1.3500342456184196,3.2302833584...
3,376
Lysosomal lumen
23
35
4.464938
0.000008
P06865,P38435,P50897,O14773,P04066,Q14108,Q9UM22,P10253,P06280,Q99538,Q9UMR5,P10619,P11117,P15586,Q8IV08,P07602,P04062,P16278,P17900,Q8NHP8,Q13510,P54802,O00584
Localization
GO Cellular component
msigdb_gocc
262,148,22,25,291,37,43,182,310,184,66,68,197,319,81,333,90,93,353,108,111,121,252
252,790,25,506,90,291,310,262,333,1185,1092,381,182,68,197,2136,319,93,353,148,2922,1835,22,121,812,111,37,81,2421,108,184,1650,444,43,66
1.4050887812930244,0.4439885391534624,3.190224570239214,0.7815125855528189,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,1.135880610204166,0.15115574181980668,0.2077445134366247,1.0315318217278158,1.7685881177452407,2.67513802823974,1.655726557404686,-0.33281539857511017,1.179718982402758,2...
3,376
Anion transport
37
75
4.411078
0.00001
O43681,O43865,O95563,P21796,P45880,P04083,Q9UHG3,Q9BQT8,Q7L0J3,P55011,P08195,Q9Y619,P12235,P11166,Q9H2D1,Q86VD7,Q9HC21,P30825,P51798,Q9NZJ7,Q15041,Q9C0H2,P53985,O75915,Q9NZD2,Q9UBX3,Q6KCM7,P07602,P08183,Q9NW15,Q9Y277,O60831,Q08722,Q8TB61,Q9HD26,Q9UJS0,P12236
Processes and pathways
GO Biological process
msigdb_gobp
506,386,508,8,11,393,17,533,281,411,525,675,154,408,42,177,438,56,311,444,570,63,199,454,210,83,212,333,216,362,231,483,621,109,501,642,497
881,1699,3133,1062,506,2009,386,483,769,454,508,393,1118,1796,333,216,525,1187,408,154,497,677,8,2015,2268,56,2722,11,311,773,199,411,1300,1158,621,1303,1161,1201,570,2283,1384,743,212,3356,780,2196,281,177,109,1044,1532,1500,533,63,1362,42,3166,1138,1604,438,501,362,210,444,83,17,2780,642,231,1658,1864,825,675,2550,86...
0.3548007225100377,-0.12407556372432456,-1.1071432230243936,0.2264292404709339,0.7815125855528189,-0.26906464190792506,1.0163834713233377,0.8296696426224738,0.4615839958458578,0.8772224665898438,0.7815125855528189,1.0011735038559333,0.18897117543040606,-0.16497606147263494,1.135880610204166,1.5391760995751391,0.7490655...
3,376
Transporters
155
385
4.344051
0.000014
O43681,O15126,O76024,Q15363,O95563,Q5J8M3,Q9H061,P45880,Q8N1F7,Q9BQT8,Q8N4V1,Q8WY22,Q13555,P35670,P08195,Q9BSK2,Q9NV70,Q14108,Q8N511,O15260,P11717,Q9H2D1,O43933,Q15629,Q9H2C2,O96008,O94901,P30825,Q9Y3B3,Q14849,Q9C0H2,Q16739,Q5VW38,P49069,Q5BJF2,Q9UBX3,Q6PML9,P40855,O75844,Q9UBQ0,Q99720,O60637,Q8TEX9,Q08722,Q8TB61,Q9HC0...
Functions
Protein Atlas Protein class
protein_atlas_protein_class
506,505,507,5,508,519,10,11,532,533,19,20,528,526,525,28,553,37,40,39,542,42,539,50,53,557,556,56,57,58,63,64,65,569,77,83,594,591,88,89,96,102,623,621,109,112,113,616,642,130,628,133,135,654,142,648,143,144,646,146,668,153,667,154,675,157,161,163,664,685,684,679,169,177,178,689,188,690,719,193,196,199,200,203,207,208,...
1661,1866,2636,881,768,3168,826,2129,1399,446,1918,1737,1326,1699,3169,1619,2637,157,505,885,914,39,616,1062,2008,2884,1573,506,1920,200,432,2009,386,539,329,963,1547,102,387,2811,2553,646,888,483,289,2303,3082,2132,1217,1970,769,770,88,454,343,507,2753,556,1794,2915,1514,1011,723,238,2050,1150,294,2259,508,2754,133,55...
-0.10377915671823269,-0.20629282062173515,-0.5981577547393172,0.3548007225100377,0.4615839958458578,-1.185066492546918,0.4085574264207841,-0.33281539857511017,0.03550516234149863,0.8929413902574874,-0.22710959688583782,-0.14447423395217424,0.07442888489169129,-0.12407556372432456,-1.185066492546918,-0.0835841298387108,...
3,376
Anion transmembrane transport
24
45
4.313149
0.000016
O95563,P21796,P45880,Q9UHG3,Q9BQT8,P55011,P08195,P12235,Q9H2D1,Q86VD7,Q9HC21,P51798,P30825,Q15041,P53985,O75915,Q9UBX3,P08183,Q9Y277,O60831,Q8TB61,Q9HD26,Q9UJS0,P12236
Processes and pathways
GO Biological process
msigdb_gobp
508,8,11,17,533,411,525,154,42,177,438,311,56,570,199,454,83,216,231,483,109,501,642,497
1062,2009,483,769,454,508,1118,1796,216,525,154,497,8,56,2722,11,311,773,199,411,1300,1158,1161,1201,570,1384,743,177,109,1044,1532,533,42,1138,1604,438,501,83,17,642,231,1658,1864,675,861
0.2264292404709339,-0.26906464190792506,0.8296696426224738,0.4615839958458578,0.8772224665898438,0.7815125855528189,0.18897117543040606,-0.16497606147263494,1.5391760995751391,0.7490655969974919,1.9607270744213334,0.7976328933322394,3.555036482266552,2.7958932046881895,-0.6440760551569396,3.4381474194828905,1.208658359...
3,376
Lysosome
28
50
4.292682
0.000018
P06865,O75503,P50897,O14773,O15118,P04066,Q14108,Q9Y487,Q15904,P10253,P06280,Q99538,Q9NZJ7,Q93050,Q9UMR5,P10619,P11117,P15586,P07602,Q8NCC3,P04062,P16278,P17900,P11279,Q13510,P20645,P54802,P08236
Processes and pathways
KEGG Pathways
msigdb_kegg
262,137,22,25,157,291,37,423,295,182,310,184,444,188,66,68,197,319,333,85,90,93,353,356,111,374,121,381
2046,790,2961,25,157,506,1920,137,90,291,310,262,333,1185,381,1876,2966,182,68,197,356,542,319,93,353,374,2922,22,121,456,812,3227,2100,949,111,37,295,85,188,668,184,716,444,911,1006,3309,66,3062,720,423
-0.2902048261296045,0.4439885391534624,-0.8571497916635558,3.190224570239214,1.9136707952245202,0.7815125855528189,-0.22710959688583782,2.0415749265642926,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,1.135880610204166,0.15115574181980668,1.0315318217278158,-0.20629282062173515,-0.857149791...
3,376
Cation transmembrane transporter activity
27
74
4.267295
0.00002
P00846,Q9HD20,P00403,Q8N4V1,P55011,P35670,P12235,O75964,P13073,Q9Y487,Q6P4Q7,O43772,Q86VD7,P16615,Q9HC21,Q8WWI5,P30825,Q93050,Q13423,Q9UDW1,P61421,Q9NW15,Q9NVV0,Q9HC07,Q70HW3,P24539,O95202
Functions
GO Molecular function
msigdb_gomf
7,135,267,19,411,526,154,31,161,423,300,432,177,302,438,443,56,188,194,74,456,362,237,112,113,240,238
1437,432,2009,2134,31,238,267,7,628,1671,1118,1220,2786,1405,525,1186,2012,154,161,302,829,793,1123,2891,240,2228,56,889,526,2143,1411,1798,2316,3086,411,1096,968,456,2568,1262,1300,1381,194,1344,1384,743,300,594,113,1386,177,19,820,443,1647,188,1532,3301,3166,1138,1604,112,438,135,237,362,74,911,2826,1658,423,2081,675...
0.015900464346774338,0.9241840457318883,-0.26906464190792506,-0.33281539857511017,3.091955963388661,1.445839319599628,1.3500342456184196,3.576464581247993,0.6164499083295459,-0.10377915671823269,0.18897117543040606,0.1321121623528798,-0.6905032048336213,0.03550516234149863,0.7490655969974919,0.15115574181980668,-0.2690...
3,376
Intrinsic component of organelle membrane
62
132
4.266411
0.00002
O60830,P10321,O15126,Q99595,O76024,O95563,Q5J8M3,Q5SNT2,O95470,P57088,O75431,P04439,Q8N4V1,Q9Y4P3,Q86YN1,Q7L0J3,Q9Y512,P12235,O15118,O75880,O43505,O60499,Q9BUN8,Q14739,P57105,Q15629,O96008,O94901,Q9BWH2,Q9HC21,Q9Y2R0,O14925,Q15041,P49069,Q9GZY8,O43752,Q9HCU5,Q13505,O95070,Q15388,Q9UH99,Q969X5,Q03518,Q9P0S2,Q9BUR5,O7584...
Localization
GO Cellular component
msigdb_gocc
0,509,505,3,507,508,519,520,265,395,392,273,19,276,149,281,416,154,157,290,538,41,430,428,427,50,557,556,312,438,61,190,570,569,327,200,328,76,204,206,342,339,334,214,477,88,589,481,92,346,476,97,354,230,359,106,492,109,243,366,118,514
1661,589,1370,190,157,505,914,2884,538,200,2009,886,41,0,366,392,88,290,507,2305,556,204,723,265,508,557,273,509,154,829,492,2403,3033,727,2520,3127,118,569,359,2318,1154,395,427,1484,2568,1262,1300,334,1199,76,2533,428,2694,570,243,2330,206,50,925,2933,2105,731,744,1683,519,520,849,230,870,611,281,2734,92,871,149,819,...
-0.10377915671823269,0.6667202646970376,0.055014368762545285,1.6937468932790258,1.9136707952245202,0.7815125855528189,0.3367165517731276,-0.784923636467135,0.7327378977030797,1.630152502007486,-0.26906464190792506,0.3548007225100377,3.007676347681497,4.625302186087037,1.0616453881949772,1.0011735038559333,2.52016653005...
3,376
Inorganic molecular entity transmembrane transporter activity
28
78
4.240532
0.000022
O43681,P00846,P21796,Q9HD20,P45880,P00403,Q8N4V1,P55011,P35670,P12235,O75964,P13073,Q9Y487,Q6P4Q7,P16615,P51798,Q93050,Q9C0H2,Q13423,Q9UDW1,P61421,Q9UBX3,Q9Y277,Q9NW15,Q9NVV0,Q9HC07,P24539,O95202
Functions
GO Molecular function
msigdb_gomf
506,7,8,135,11,267,19,411,526,154,31,161,423,300,302,311,188,63,194,74,456,83,231,362,237,112,240,238
881,1437,1062,506,2134,31,238,267,7,628,1671,1118,1220,2786,1405,525,1186,1187,2012,154,161,302,829,793,1123,2891,8,240,2228,889,526,2143,1411,1798,11,2316,3086,311,411,1096,968,456,2568,1262,1300,1381,1158,194,1344,743,3356,300,1386,19,820,1044,1647,188,1500,2115,63,3301,3166,1138,112,135,237,362,83,74,911,2826,231,16...
0.3548007225100377,0.015900464346774338,0.2264292404709339,0.7815125855528189,-0.33281539857511017,3.091955963388661,1.445839319599628,1.3500342456184196,3.576464581247993,0.6164499083295459,-0.10377915671823269,0.18897117543040606,0.1321121623528798,-0.6905032048336213,0.03550516234149863,0.7490655969974919,0.15115574...
3,376
Ion transmembrane transporter activity
43
108
4.22095
0.000024
O43681,O95563,P00846,P21796,Q9HD20,P45880,P00403,Q9BQT8,Q8N4V1,P55011,P35670,P12235,O75964,P11166,P13073,Q9Y487,Q9H2D1,Q6P4Q7,O43772,Q86VD7,P16615,Q9HC21,Q8WWI5,P30825,P51798,Q93050,Q9C0H2,Q13423,P53985,Q9UDW1,P61421,Q9UBX3,Q6KCM7,Q9Y277,Q6P4A7,Q9NW15,Q8TB61,Q9NVV0,Q9HC07,Q70HW3,P24539,O95202,P12236
Functions
GO Molecular function
msigdb_gomf
506,508,7,8,135,11,267,533,19,411,526,154,31,408,161,423,42,300,432,177,302,438,443,56,311,188,63,194,199,74,456,83,212,231,230,362,109,237,112,113,240,238,497
881,1437,1699,1062,506,432,2009,769,2134,31,238,508,267,7,628,1671,1118,1220,2786,1405,525,1186,1187,2012,408,154,497,161,302,829,793,1123,2891,8,240,2228,56,889,526,2143,1411,1798,2722,11,2316,3086,311,773,199,411,1096,968,456,2568,1262,1300,1381,1158,194,1201,1265,1344,1384,743,212,3356,780,2196,230,300,594,113,1386,...
0.3548007225100377,0.015900464346774338,-0.12407556372432456,0.2264292404709339,0.7815125855528189,0.9241840457318883,-0.26906464190792506,0.4615839958458578,-0.33281539857511017,3.091955963388661,1.445839319599628,0.7815125855528189,1.3500342456184196,3.576464581247993,0.6164499083295459,-0.10377915671823269,0.1889711...
3,376
Sphingolipid metabolic process
21
33
4.207171
0.000026
P06865,O95470,P30153,P50897,Q96G23,Q9H2C2,P06280,Q9NZJ7,Q16739,Q99805,Q9NZD2,P07602,Q8NCC3,Q9P035,P04062,P16278,P17900,Q06136,Q9NRA0,Q13510,O15121
Processes and pathways
GO Biological process
msigdb_gobp
262,265,268,22,167,53,310,444,64,196,210,333,85,481,90,93,353,98,489,111,123
123,491,1868,590,265,90,310,262,333,1185,93,353,1750,268,22,98,1303,111,64,744,85,167,196,53,489,2120,1173,1464,210,444,481,2435,825
2.1428207883227306,0.8136850803085195,-0.20629282062173515,0.6667202646970376,1.3638760848112592,2.4902865084460193,1.208658359818944,1.3776655599934584,1.135880610204166,0.15115574181980668,2.470216891564265,1.1063642295621396,-0.14447423395217424,1.3500342456184196,3.2302833584863713,2.429712971519325,0.0937495024862...
3,376
Mitochondrial transport
44
90
4.163071
0.000031
O60830,Q9NS69,Q99595,P00846,P45880,O75431,P55786,Q9P0J0,Q5JRX3,Q9Y512,P12235,O43615,O75964,Q9Y371,P49257,O14737,O43772,O96008,P52789,Q8N4H5,Q14849,Q96EP0,O14925,Q9GZY8,P49841,Q96EK5,Q15388,Q9Y5J9,Q9UBX3,O43464,O95140,Q10713,O00165,P50416,Q96DA6,Q53H12,O00170,P49840,Q15070,Q8TB36,P24539,Q9UJS0,Q8WWC4,P23786
Processes and pathways
GO Biological process
msigdb_gobp
0,2,3,7,11,392,145,283,412,416,154,405,31,685,679,298,432,557,304,54,58,571,190,327,330,466,206,737,83,590,723,608,602,359,624,744,482,364,243,761,240,642,762,120
602,482,298,190,590,405,432,0,392,2219,2134,31,2305,723,3233,1743,1372,557,7,1473,1118,1220,1092,1745,2967,154,2834,120,240,2228,2994,2310,2268,2187,2143,2644,11,3086,1376,679,364,330,359,1154,304,145,1096,968,2098,608,1303,58,243,206,2535,2933,833,744,412,780,2335,1848,1897,54,2422,761,762,624,466,571,1853,3,2115,1601...
0.6500364914113959,0.8296696426224738,1.2373723709299225,1.6937468932790258,0.6667202646970376,0.9705669749994547,0.9241840457318883,4.625302186087037,1.0011735038559333,-0.37587289727828466,-0.33281539857511017,3.091955963388661,-0.41938548886236693,0.5138974074088837,-1.3452365310224934,-0.14447423395217424,0.0550143...
3,376
Transporter activity
74
184
4.162783
0.000031
O43681,O60830,Q9NS69,Q99595,Q8WTV0,O95563,P00846,P21796,Q9HD20,P45880,Q9H2V7,P00403,Q96GC9,O96000,Q9BQT8,Q8N4V1,P38435,Q7L0J3,Q9P0J0,P35670,P03886,P55011,O43676,Q9BSK2,P12235,O15118,O75964,O95168,P13073,O75027,P11166,Q9Y487,Q9H2D1,Q6P4Q7,O43772,Q86VD7,P16615,Q9H2C2,Q07820,Q9HC21,Q8WWI5,P30825,P51798,Q14849,Q93050,O1492...
Functions
GO Molecular function
msigdb_gomf
506,0,2,3,130,508,7,8,135,11,142,267,144,272,533,19,148,281,283,526,24,411,26,28,154,157,31,278,161,289,408,423,42,300,432,177,302,53,435,438,443,56,311,58,188,190,63,194,199,72,74,456,206,207,210,334,83,212,216,90,353,231,230,362,485,109,237,112,113,240,238,367,245,497
589,881,1618,1737,1437,1326,1699,190,157,72,1062,2716,26,1028,506,432,2009,0,289,2049,367,1670,769,2134,31,2305,278,704,238,2443,508,272,557,267,7,24,90,628,1671,1118,1220,2786,1405,216,525,1186,1187,2012,408,154,497,161,302,353,2889,829,793,1123,2891,8,1750,240,2228,2015,2947,2268,56,889,526,2143,1411,148,1798,2722,11...
0.6667202646970376,0.3548007225100377,-0.0835841298387108,-0.14447423395217424,0.015900464346774338,0.07442888489169129,-0.12407556372432456,1.6937468932790258,1.9136707952245202,2.637070673082067,0.2264292404709339,-0.6440760551569396,3.1659423425394335,0.2450260771368476,0.7815125855528189,0.9241840457318883,-0.26906...
3,376
er
40
85
4.152821
0.000033
O14735,Q15363,O96005,Q5J8M3,O95470,Q16850,Q96GC9,Q8N4V1,Q86SK9,O00264,Q9P2W9,Q9P0I2,Q9Y487,O60499,Q14739,Q96N66,Q9Y5M8,Q9NTJ5,Q15041,Q15392,Q99640,Q07065,Q969Q5,O15173,O75915,Q8NHH9,P84085,P46977,Q8NF37,Q9H6H4,Q96A33,Q13190,Q06136,P49755,Q9NR31,Q9NQC3,O15269,P48651,O15121,Q9Y3E0
Localization
OpenCell Localization
opencell_localization
626,5,133,519,265,141,144,19,530,277,29,684,423,41,428,301,174,572,570,191,192,321,69,72,454,208,592,461,464,478,346,474,98,485,625,106,491,241,123,517
277,1370,626,123,72,491,1868,2884,41,2303,2131,454,2050,265,133,1404,791,2483,2887,1030,1797,727,1192,461,920,241,485,2056,2523,1154,2148,3069,2020,1711,797,3200,592,1486,798,98,321,474,428,2694,570,5,191,1203,2244,141,519,695,2196,530,2905,928,19,1849,464,208,2702,1313,69,1274,346,144,301,192,1728,1427,3239,2003,478,2...
1.322192093055503,0.055014368762545285,0.6164499083295459,2.1428207883227306,2.637070673082067,0.8136850803085195,-0.20629282062173515,-0.784923636467135,3.007676347681497,-0.41938548886236693,-0.33281539857511017,0.8772224665898438,-0.2902048261296045,1.3638760848112592,2.075654841379259,0.03550516234149863,0.44398853...
3,376
Protein localization
35
76
4.106037
0.00004
O43681,O60830,Q9NS69,Q99595,P21796,Q7L5D6,O75431,P46379,P09601,P05067,O00116,Q9NR77,Q5JRX3,Q9Y512,P12235,O43615,P50402,O43933,Q13011,O96008,Q8N4H5,O14734,O14925,P49069,Q13505,Q15388,P40855,Q13190,Q10713,P12236,Q96DA6,Q15067,Q9UJS0,P51648,P50542
Processes and pathways
Reactome Pathways
msigdb_reactome
506,0,2,3,8,521,392,140,15,143,645,153,412,416,154,405,417,539,305,557,54,439,190,569,76,206,591,474,608,497,624,622,642,119,382
645,439,190,1182,1148,405,506,703,2009,539,0,3205,392,2219,2479,769,3066,2305,557,143,1220,1186,3114,15,2967,154,497,1703,8,1254,2228,2015,3034,3127,591,140,569,417,382,119,1756,3069,608,305,474,76,622,206,833,412,899,521,54,1310,2422,761,2507,624,3,2907,2879,1651,1856,153,2,671,2435,1175,642,2957,1613,1786,416,1146,73...
0.5995459898347874,0.9085950944992713,1.6937468932790258,0.15115574181980668,0.17010849742073567,0.9705669749994547,0.7815125855528189,0.5311795854762361,-0.26906464190792506,0.7327378977030797,4.625302186087037,-1.2644156881924795,1.0011735038559333,-0.37587289727828466,-0.5078096934092219,0.4615839958458578,-0.980321...
3,376
Mitochondrial transmembrane transport
32
55
4.101102
0.000041
O60830,Q99595,O95563,Q9BPX6,P21796,P00846,O75746,P53007,Q9BQT8,Q9Y619,P12235,Q9BSK2,O43615,O75964,O75027,Q9H2D1,Q8NE86,O43772,O96008,Q3ZCQ8,O14925,Q8IYU8,Q15388,Q6P4A7,P50416,Q96DA6,Q8WWC4,P24539,O95202,Q9UJS0,P12236,P23786
Processes and pathways
GO Biological process
msigdb_gobp
0,3,508,654,8,7,769,773,533,675,154,28,405,31,289,42,820,432,557,833,190,834,206,230,359,624,762,240,238,642,497,120
190,405,432,0,289,2219,769,2134,31,2305,238,508,1372,557,7,1118,1220,2967,154,497,8,120,240,2228,2143,3086,359,773,1096,968,1300,206,832,833,230,834,820,2422,3044,762,624,1532,3,654,533,28,42,1138,1604,1856,1543,642,1431,1659,675
1.6937468932790258,0.9705669749994547,0.9241840457318883,4.625302186087037,1.2941363054249848,-0.37587289727828466,0.4615839958458578,-0.33281539857511017,3.091955963388661,-0.41938548886236693,1.445839319599628,0.7815125855528189,0.055014368762545285,0.7163400404236764,3.576464581247993,0.18897117543040606,0.132112162...
3,376
Intrinsic component of mitochondrial membrane
30
51
4.003254
0.000062
O60830,Q99595,O95563,Q9BPX6,O75431,Q9NX63,Q9NVH1,Q9Y512,P12235,O75880,Q8NE86,P57105,O96008,Q9HC21,Q9BWH2,Q9Y2R0,O14925,Q9GZY8,Q13505,Q15388,Q9P0S2,Q9BUR5,Q16891,O95140,Q9H3K2,Q6P4A7,P50416,Q53H12,Q15070,Q8TB36
Localization
GO Cellular component
msigdb_gocc
0,3,508,654,392,671,669,416,154,290,820,427,557,438,312,61,190,327,76,206,214,477,731,723,354,230,359,744,243,761
190,886,0,392,290,2305,723,508,557,154,3127,359,427,1300,76,243,206,925,2933,731,744,1683,849,230,870,819,1848,1897,820,761,1532,3,654,1004,477,312,327,354,1604,2590,438,1732,669,671,214,1366,1282,61,1659,416,1215
1.6937468932790258,0.3548007225100377,4.625302186087037,1.0011735038559333,1.2941363054249848,-0.41938548886236693,0.5138974074088837,0.7815125855528189,0.7163400404236764,1.9607270744213334,-1.0814780591807345,1.0915175946894244,0.9397087056445106,0.09374950248621658,2.598559042970186,1.445839319599628,1.5784489587449...
3,376
Endoplasmic reticulum organization
31
49
3.978798
0.000069
O43681,O15027,Q15363,Q5J8M3,P57088,Q7L5D6,P46379,Q8N4V1,Q00765,Q9P2W9,P61026,O95197,Q9P0I2,O14657,P49257,O14976,Q9Y5P4,Q15629,Q6NUK4,Q15041,P49069,O00429,Q8N5M9,O43765,Q8NHH9,Q9H6H4,Q96A33,Q9NQC3,Q9H2M9,Q9NVV0,P50542
Processes and pathways
GO Biological process
msigdb_gobp
506,627,5,519,395,521,140,19,798,29,797,30,684,297,679,676,825,50,695,570,569,826,202,703,208,478,346,106,365,237,382
1661,826,297,676,627,2884,506,703,1514,30,2050,140,569,679,382,395,797,2568,798,831,2694,570,2283,5,50,519,1385,695,521,19,202,1849,2033,208,346,1728,2003,365,2386,478,2070,908,106,237,1173,684,2435,29,825
-0.10377915671823269,0.4085574264207841,1.2373723709299225,0.565514082039327,0.6164499083295459,-0.784923636467135,0.7815125855528189,0.5311795854762361,-0.023598660010764588,3.108547336875158,-0.2902048261296045,2.030139933980146,0.6998715023470454,0.565514082039327,1.0315318217278158,1.0011735038559333,0.443988539153...
3,376
Sphingolipid metabolism
18
28
3.972117
0.000071
Q16739,P17900,Q06136,P10619,Q9NRA0,P06865,Q96G23,O95470,O15269,O15121,Q13510,Q9NZD2,P51648,P07602,P06280,Q9NZJ7,P04062,P16278
Processes and pathways
Reactome Pathways
msigdb_reactome
64,353,98,68,489,262,167,265,491,123,111,210,119,333,310,444,90,93
1661,123,491,1868,506,2050,265,90,310,262,333,1185,68,93,353,1750,119,98,111,64,167,1728,489,1173,210,444,2435,825
-0.10377915671823269,2.1428207883227306,0.8136850803085195,-0.20629282062173515,0.7815125855528189,-0.2902048261296045,1.3638760848112592,2.4902865084460193,1.208658359818944,1.3776655599934584,1.135880610204166,0.15115574181980668,2.67513802823974,2.470216891564265,1.1063642295621396,-0.14447423395217424,2.17591786960...
3,376
Mitochondrial respiratory chain complex assembly
17
45
3.947729
0.000079
O75880,Q69YU5,Q9H061,Q86Y39,Q96CU9,O96000,O95168,Q15070,O75306,Q9P0J0,Q9P0S2,P03886,Q9Y512,O43676,Q9BSK2,Q9Y2R0,Q6DKK2
Processes and pathways
GO Biological process
msigdb_gobp
290,6,10,187,78,272,278,243,367,283,214,24,416,26,28,61,253
2716,26,1028,886,2049,367,1670,290,278,2443,1372,272,24,2947,2316,1015,2019,2371,243,1344,2412,1895,6,253,781,187,2160,2112,78,420,957,1459,28,2938,10,1462,1249,3012,283,214,3258,1613,61,416,721
-0.6440760551569396,3.1659423425394335,0.2450260771368476,0.3548007225100377,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.2941363054249848,1.322192093055503,-0.4855260677859258,0.055014368762545285,1.3361396976874031,3.214321038100156,-0.8329374006846979,-0.41938548886236693,0.2635357357357556,-0.26906...
3,376
Anion transmembrane transporter activity
21
48
3.928443
0.000085
O43681,O95563,P21796,P45880,Q9BQT8,P55011,P12235,P11166,Q9H2D1,Q86VD7,Q9HC21,P51798,P30825,Q9C0H2,P53985,Q9UBX3,Q6KCM7,Q9NW15,Q9Y277,Q8TB61,P12236
Functions
GO Molecular function
msigdb_gomf
506,508,8,11,533,411,154,408,42,177,438,311,56,63,199,83,212,362,231,109,497
881,1699,1062,506,2009,769,508,1118,525,1187,408,154,497,8,56,2722,11,311,773,199,411,1158,1201,1384,743,212,3356,780,2196,177,109,1044,1532,1500,533,63,42,1138,1604,438,362,83,642,231,1658,675,2550,861
0.3548007225100377,-0.12407556372432456,0.2264292404709339,0.7815125855528189,-0.26906464190792506,0.4615839958458578,0.7815125855528189,0.18897117543040606,0.7490655969974919,0.15115574181980668,0.9705669749994547,1.9607270744213334,0.7976328933322394,3.555036482266552,2.7958932046881895,-0.6440760551569396,3.43814741...
3,376
Nuclear outer membrane endoplasmic reticulum membrane network
120
315
3.925656
0.000086
P10321,O76024,Q15363,Q5J8M3,P67812,P09601,Q8N4V1,Q13555,Q86SK9,A1L0T0,Q9P2W9,O95197,P30519,P43307,Q14108,Q8N511,O15260,Q15629,Q9H2C2,Q9NTJ5,Q9Y3B3,Q14849,Q15041,P49069,Q8TC12,Q4ZIN3,Q7Z2K6,Q5BJF2,Q9H0U4,Q8IV08,O43464,O75844,Q9BRR6,Q86XL3,Q99720,Q9Y282,Q06136,Q9NQC3,Q8TB61,Q15800,P51648,O15121,O60725,Q9NZ08,P07099,Q9HD2...
Localization
GO Cellular component
msigdb_gocc
509,507,5,519,13,15,19,528,530,524,29,30,33,34,37,40,39,50,53,572,57,58,570,569,583,70,595,77,599,81,590,88,91,92,96,97,98,106,109,116,119,123,126,127,134,135,141,144,146,148,149,165,167,173,174,178,191,192,202,204,208,221,228,229,235,237,241,249,256,261,265,266,273,276,280,277,285,286,288,295,296,301,302,323,321,328,3...
1661,524,277,826,1436,446,1370,1737,657,1326,626,1867,1919,2637,627,123,39,491,1868,1572,2884,590,472,386,1063,1741,126,1668,366,2303,2131,1217,770,88,454,507,1700,2831,1794,2679,1514,204,30,2050,265,2221,2482,1873,2603,1404,261,273,791,2483,1119,2756,134,2887,1443,15,509,2308,266,302,1122,917,2449,1750,2606,2858,3033,...
-0.10377915671823269,0.7490655969974919,1.322192093055503,0.4085574264207841,0.015900464346774338,0.8929413902574874,0.055014368762545285,-0.14447423395217424,0.5825675708995396,0.07442888489169129,0.6164499083295459,-0.20629282062173515,-0.22710959688583782,-0.5981577547393172,0.6164499083295459,2.1428207883227306,3.0...
3,376
Golgi membrane
62
135
3.879172
0.000105
P35613,P10321,O15027,Q15363,Q9BXS4,P57737,Q8NBN3,P52292,P04439,Q9H3P7,Q8N4V1,P35670,Q9P2W9,P40616,O95197,Q10472,P11166,O14579,O43505,Q8IZA0,Q14108,Q9Y371,P11717,O15260,O60499,P49257,Q8NCH0,Q9NTJ5,Q9Y3B3,Q15392,Q16739,Q99640,Q9BXS5,Q13464,Q9H7Z7,O43752,O95249,Q9BVK6,O95070,Q9UBF8,Q9H0U4,O00461,Q8IV08,Q96MW5,Q969X5,Q9H4A...
Localization
GO Cellular component
msigdb_gocc
256,509,627,5,397,396,12,648,273,402,19,526,29,544,30,285,408,657,538,164,37,685,542,39,41,679,44,572,57,191,64,192,716,322,459,200,201,332,204,469,599,80,81,736,339,213,464,477,589,217,474,95,611,97,608,486,485,109,112,501,250,517
589,80,657,2961,627,914,39,1740,538,3196,1920,200,41,1669,2131,204,30,201,1874,273,1443,1187,509,408,542,2449,1750,2921,1191,256,526,1706,544,1224,1836,2368,679,485,730,2056,1154,648,1225,2813,2320,396,1016,2235,2611,1711,797,1677,2925,3227,2188,1229,1197,1262,2864,1841,1199,285,949,608,831,474,322,37,1718,3246,2900,5,...
0.6667202646970376,2.5693783360444082,0.5825675708995396,-0.8571497916635558,0.6164499083295459,0.3367165517731276,3.016205187599177,-0.14447423395217424,0.7327378977030797,-1.2378047400733483,-0.22710959688583782,1.630152502007486,3.007676347681497,-0.10377915671823269,-0.33281539857511017,1.6043940725091548,3.1085473...
3,376
SLC superfamily of solute carriers
29
48
3.875531
0.000106
O95563,Q9H2V7,Q9BQT8,Q7L0J3,P55011,P08195,Q96K37,P12235,Q9BSK2,P11166,Q9H2D1,O43772,Q86VD7,Q9HC21,Q8WWI5,P30825,Q9NZJ7,P53985,Q8IXU6,Q9UBX3,Q6KCM7,Q6PML9,Q9Y6C9,Q8TB61,Q9HC07,Q70HW3,O95202,Q9UJS0,P12236
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
508,142,533,281,411,525,667,154,28,408,42,432,177,438,443,56,444,199,207,83,212,594,490,109,112,113,238,642,497
432,2009,769,238,508,1118,525,408,154,497,56,2722,773,199,411,1300,1158,1384,212,3356,780,2196,594,113,281,177,207,109,443,667,1532,533,28,3301,42,3166,142,1138,1604,112,438,444,83,642,1658,675,490,861
0.9241840457318883,-0.26906464190792506,0.4615839958458578,1.445839319599628,0.7815125855528189,0.18897117543040606,0.7490655969974919,0.9705669749994547,1.9607270744213334,0.7976328933322394,2.7958932046881895,-0.6440760551569396,0.4615839958458578,1.6429624336734927,0.9705669749994547,0.09374950248621658,0.1701084974...
3,376
Inner mitochondrial membrane protein complex
21
80
3.819725
0.000134
O60830,Q99595,P00846,P00403,O75431,O96000,Q9P0J0,P03886,O95168,O43676,O75964,P13073,Q86Y39,O14925,P14406,Q9UDW1,Q13505,Q96CU9,O14949,P24539,O75306
Localization
GO Cellular component
msigdb_gocc
0,3,7,267,392,272,283,24,278,26,31,161,187,190,62,74,76,78,87,240,367
1618,1437,190,87,2716,26,1028,0,2049,367,392,1670,2134,31,278,704,2443,272,267,7,24,1220,1186,2012,497,161,62,3145,1189,2889,793,918,754,240,2228,2947,2450,889,1704,2143,3127,2316,3086,3226,1015,1096,968,2019,76,2412,1895,731,833,744,1683,849,870,187,834,820,2422,78,624,903,3,1208,654,477,1856,669,1249,671,283,74,3258,...
-0.0835841298387108,0.015900464346774338,1.6937468932790258,2.530067311521496,-0.6440760551569396,3.1659423425394335,0.2450260771368476,4.625302186087037,-0.2902048261296045,1.0616453881949772,1.0011735038559333,-0.10377915671823269,-0.33281539857511017,3.091955963388661,1.322192093055503,0.5311795854762361,-0.48552606...
3,376
Lipid localization
26
78
3.769745
0.000163
Q8WTV0,P04083,Q9H2V7,Q96GC9,P09455,O15118,P11166,Q14108,O15260,Q9H6V9,P35790,O43772,Q9H2C2,Q9NZJ7,Q14849,Q16739,Q9NZD2,P07602,P08183,P04062,Q99720,P17900,P50416,P31751,Q14534,P23786
Processes and pathways
GO Biological process
msigdb_gobp
130,393,142,144,284,157,408,37,39,45,48,432,53,444,58,64,210,333,216,90,96,353,359,232,235,120
1661,3369,1737,1326,157,39,1062,432,2009,863,647,2221,1873,2946,90,393,2786,333,1185,2011,216,284,408,677,353,1094,1750,1254,120,2015,2268,232,630,1068,48,2368,359,812,2653,2325,1303,37,235,58,64,743,1812,2196,871,3106,130,979,1458,2205,144,1020,96,1728,477,1820,3239,1279,53,142,639,45,3111,210,444,2435,909,2121,880,14...
-0.10377915671823269,-5.788717024452099,-0.14447423395217424,0.07442888489169129,1.9136707952245202,3.016205187599177,0.2264292404709339,0.9241840457318883,-0.26906464190792506,0.372801821409757,0.5995459898347874,-0.37587289727828466,-0.20629282062173515,-0.8329374006846979,2.4902865084460193,1.0011735038559333,-0.690...
3,376
Intrinsic component of endoplasmic reticulum membrane
25
53
3.722927
0.000197
P10321,O76024,Q5J8M3,P57088,O95470,P04439,Q8N4V1,Q9Y4P3,Q86YN1,Q9BUN8,Q15629,Q15041,Q9HCU5,Q969X5,Q03518,Q9P035,O75844,Q86XL3,Q99442,Q96A33,Q9Y282,Q9NQC3,Q8TB61,O75298,Q8TCT9
Localization
GO Cellular component
msigdb_gocc
509,507,519,395,265,273,19,276,149,430,50,570,328,339,334,481,88,92,476,346,97,106,109,366,514
1661,1370,2884,366,88,507,265,273,509,3033,727,2520,569,1154,395,2568,334,2533,2694,570,50,2105,519,2734,92,149,19,1849,109,514,1273,1355,339,346,934,476,1728,430,2003,878,328,908,106,1464,481,684,2436,2546,3219,2826,97,276,913
-0.10377915671823269,0.055014368762545285,-0.784923636467135,1.0616453881949772,2.5201665300557425,0.7815125855528189,1.3638760848112592,1.3361396976874031,0.7815125855528189,-0.9306254080954044,0.5138974074088837,-0.5302135415922944,0.6998715023470454,0.17010849742073567,1.0011735038559333,-0.552738738110152,1.1358806...
3,376
Organic anion transport
31
53
3.707654
0.000209
Q6NUK1,O95563,P04083,O75746,P53007,Q9BQT8,Q7L0J3,P55011,P08195,Q9Y619,P12235,P11166,Q9H2D1,P14174,Q9Y5P4,Q86VD7,Q9HC21,P30825,Q9NZJ7,Q15041,P53985,O75915,Q9NZD2,Q9UBX3,Q6KCM7,P07602,O60831,Q08722,Q8TB61,Q9UJS0,P12236
Processes and pathways
GO Biological process
msigdb_gobp
780,508,393,769,773,533,281,411,525,675,154,408,42,677,825,177,438,56,444,570,199,454,210,83,212,333,483,621,109,642,497
1699,3133,1062,2009,483,769,454,508,393,1118,1796,333,525,408,154,497,677,2015,56,2722,773,199,411,1158,621,1303,1201,570,2283,1384,212,780,2196,281,177,109,1044,1532,533,42,3166,1138,1604,438,210,444,83,2780,642,1658,825,675,861
-0.12407556372432456,-1.1071432230243936,0.2264292404709339,-0.26906464190792506,0.8296696426224738,0.4615839958458578,0.8772224665898438,0.7815125855528189,1.0011735038559333,0.18897117543040606,-0.16497606147263494,1.135880610204166,0.7490655969974919,0.9705669749994547,1.9607270744213334,0.7976328933322394,0.5655140...
3,376
Azurophil granule
24
69
3.652616
0.00026
O43681,P06865,P08236,Q92542,P04066,P27105,O15260,P10253,P06280,Q9NZJ7,O00560,Q07065,P10619,P15586,Q9H7Z7,Q9BRF8,P07602,Q8NF37,P16278,P17900,P42785,P11279,Q9NQX7,O00584
Localization
GO Cellular component
msigdb_gocc
506,262,381,400,291,163,39,182,310,444,446,321,68,319,459,209,333,464,93,353,101,356,105,252
2636,446,252,790,39,1329,506,646,1116,2400,1874,1404,291,310,262,2786,792,333,1185,381,182,68,1551,356,319,93,353,2089,163,1974,2519,1192,101,1522,1634,689,2147,988,1802,1887,2148,1838,812,892,992,2151,321,1716,1039,2615,898,1812,2421,464,400,785,1018,2168,551,1726,209,855,3301,459,105,2176,444,2435,1962
-0.5981577547393172,0.8929413902574874,1.4050887812930244,0.4439885391534624,3.016205187599177,0.07442888489169129,0.7815125855528189,0.5995459898347874,0.18897117543040606,-0.4633615537366067,-0.20629282062173515,0.03550516234149863,1.2941363054249848,1.208658359818944,1.3776655599934584,-0.6905032048336213,0.44398853...
3,376
Active transmembrane transporter activity
24
77
3.591984
0.000328
Q9HD20,P00403,O96000,P55011,Q9P0J0,P35670,P03886,P12235,O95168,O43676,P13073,O75027,P16615,P51798,P53985,Q9UDW1,P61421,Q15388,Q03518,Q9UBX3,P08183,O95202,O75306,P12236
Functions
GO Molecular function
msigdb_gomf
135,267,272,411,283,526,24,154,278,26,161,289,302,311,199,74,456,206,334,83,216,238,367,497
1618,1437,1326,1062,2716,26,1028,289,2049,367,1670,278,704,238,2443,272,267,24,628,1671,1118,1220,216,525,1186,2012,154,497,161,302,2889,829,793,1123,2891,2015,2947,889,526,1411,1798,2722,2316,3226,311,1015,773,199,411,2019,456,1262,1300,1158,334,206,1344,1384,2412,1895,1386,820,667,3166,1138,135,1732,1543,283,83,74,32...
-0.0835841298387108,0.015900464346774338,0.07442888489169129,0.2264292404709339,-0.6440760551569396,3.1659423425394335,0.2450260771368476,1.2941363054249848,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.322192093055503,0.5311795854762361,1.445839319599628,-0.4855260677859258,1.3361396976874031,1.3500342...
3,376
Abnormal circulating lipid concentration
30
75
3.520775
0.00043
P22830,O95470,P28070,O75431,Q13045,Q9Y4P3,P50402,O75880,Q15904,Q8N511,O43933,Q14739,Q16836,O43772,P06280,Q9NZJ7,P35250,Q15392,P07602,P40855,Q9P0S2,O75844,P50416,P31751,Q15800,Q9UJS0,Q9NVI7,P23786,Q9H9E3,P50542
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,265,138,392,399,276,417,290,295,40,539,428,561,432,310,444,315,191,333,591,214,88,359,232,116,642,640,120,250,382
2047,1216,432,539,392,1089,88,290,265,2306,310,1440,333,1291,3354,128,120,138,1673,232,315,2055,3034,843,2922,591,2314,1412,1675,679,632,417,359,382,2490,1756,2321,2972,1227,812,3054,2152,1524,1199,399,1641,1162,428,973,191,1203,116,898,295,561,2976,2580,40,1389,2290,1496,1355,1171,1462,250,640,444,214,2546,2988,642,91...
-0.2902048261296045,0.1321121623528798,0.9241840457318883,0.7327378977030797,1.0011735038559333,0.2077445134366247,2.5201665300557425,1.2941363054249848,1.3638760848112592,-0.41938548886236693,1.208658359818944,0.015900464346774338,1.135880610204166,0.09374950248621658,-2.699266327650186,2.098189349032581,2.16492096741...
3,376
Protein targeting
57
120
3.502847
0.00046
O43681,O60830,Q9NS69,Q99595,A5D8V6,Q7L5D6,P46379,P55786,Q96RL7,Q8N3F8,Q9P0J0,Q9H9H4,Q99523,Q15005,Q5JRX3,Q9Y512,O43615,P43307,P27105,Q7Z3T8,Q14108,Q9Y371,O43933,P49257,O14737,P57105,Q9Y5M8,Q15629,O96008,Q8N4H5,Q96EP0,O14925,Q15041,Q9UGP8,P46934,O00560,Q9Y2T2,Q9GZY8,O43765,Q15388,Q9Y5J9,P40855,O43464,Q99442,O95140,Q1071...
Processes and pathways
GO Biological process
msigdb_gobp
506,0,2,3,379,521,140,145,146,275,283,415,668,280,412,416,405,34,163,681,37,685,539,679,298,427,174,50,557,54,571,190,570,719,193,446,720,327,703,206,737,591,590,476,723,608,361,602,624,744,232,364,482,493,374,382,126
379,1866,602,482,2046,446,2961,298,3133,190,1327,590,405,506,703,539,126,0,2219,2753,2305,723,3233,1743,1372,557,1092,2887,2967,2136,2834,374,163,945,2092,2268,2186,232,1031,2921,2187,2312,591,34,140,193,679,493,364,382,2318,1154,145,427,3069,2020,2568,1713,776,2236,1156,2098,1381,608,2530,1303,37,280,570,206,50,2535,3...
1.0315318217278158,-0.20629282062173515,0.6500364914113959,0.8296696426224738,-0.2902048261296045,0.8929413902574874,-0.8571497916635558,1.2373723709299225,-1.1071432230243936,1.6937468932790258,0.07442888489169129,0.6667202646970376,0.9705669749994547,0.7815125855528189,0.5311795854762361,0.7327378977030797,2.10940159...
3,376
Respirasome
13
47
3.493548
0.000477
P13073,Q13423,Q9UDW1,P00403,Q86Y39,Q96CU9,O96000,Q6DKK2,Q9P0J0,O14949,P03886,O43676,P14406
Localization
GO Cellular component
msigdb_gocc
161,194,74,267,187,78,272,253,283,87,24,26,62
1618,1437,87,2716,26,1028,2049,367,1670,278,704,2443,272,267,24,1186,2012,161,62,3145,1189,2889,793,918,754,2947,2450,889,2316,3226,1015,2019,194,1344,2412,1895,253,1386,187,78,1249,283,74,3258,1178,1613,721
-0.0835841298387108,0.015900464346774338,2.530067311521496,-0.6440760551569396,3.1659423425394335,0.2450260771368476,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,1.3500342456184196,3.214321038100156,0.15115574181980668,-0.2690646...
3,376
Organic acid transport
24
50
3.485924
0.00049
P33121,O95563,P04083,Q9BQT8,Q7L0J3,P55011,P08195,Q9Y619,P09455,P11166,Q9H2D1,O43772,P30825,Q15041,P53985,O75915,Q9UBX3,P08183,Q6P4A7,P50416,O60831,P31751,Q9UJS0,P23786
Processes and pathways
GO Biological process
msigdb_gobp
630,508,393,533,281,411,525,675,284,408,42,432,56,570,199,454,83,216,230,359,483,232,642,120
1326,1699,3133,1062,432,2009,483,769,454,508,1873,2946,393,1796,2011,216,525,284,408,677,120,2015,56,232,630,2722,359,773,199,411,1158,1303,570,2283,1384,2196,230,281,1044,1532,533,42,3166,1138,1604,83,642,2957,1658,675
0.07442888489169129,-0.12407556372432456,-1.1071432230243936,0.2264292404709339,0.9241840457318883,-0.26906464190792506,0.8296696426224738,0.4615839958458578,0.8772224665898438,0.7815125855528189,-0.20629282062173515,-0.8329374006846979,1.0011735038559333,-0.16497606147263494,-0.26906464190792506,1.5391760995751391,0.7...
3,376
Parkinsons disease
14
56
3.466192
0.000528
P13073,Q9Y277,P00846,P21796,Q9UDW1,P45880,P12235,P00403,O96000,P24539,O14949,P03886,O43676,P14406
Processes and pathways
KEGG Pathways
msigdb_kegg
161,231,7,8,74,11,154,267,272,240,87,24,26,62
1618,1437,87,590,2716,26,1028,2049,367,1670,2134,278,704,2443,272,267,7,24,1118,1220,1186,2012,154,497,161,62,3145,1189,2889,793,8,918,2606,754,240,2228,2947,2450,889,2143,2489,11,2316,3086,3226,1015,2019,691,2098,845,2412,1895,2803,74,231,721
-0.0835841298387108,0.015900464346774338,2.530067311521496,0.6667202646970376,-0.6440760551569396,3.1659423425394335,0.2450260771368476,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,-0.33281539857511017,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,1.3500342456184196,3.576464...
3,376
Transmembrane transport
97
228
3.465731
0.000529
O60830,Q9NS69,Q99595,O95563,P00846,P21796,P45880,Q9UHG3,Q9BQT8,Q8N4V1,P35670,P08195,Q9BSK2,O75964,O43933,Q9H2D1,Q15629,O96008,P30825,Q9C0H2,Q15041,Q9UDW1,Q9UBX3,Q6PML9,O75844,L0R6Q1,P04062,P78417,Q96DA6,Q8TB61,Q9HC07,Q70HW3,Q9UJS0,P23786,P33121,Q8WTV0,P05023,Q9HD20,Q9BPX6,Q9H2V7,P05067,Q96GC9,P38435,Q99523,Q96K37,P1223...
Processes and pathways
GO Biological process
msigdb_gobp
0,2,3,508,7,8,11,17,533,19,526,525,28,31,539,42,50,557,56,63,570,74,83,594,88,589,90,94,624,109,112,113,642,120,630,130,628,135,654,142,143,144,148,668,667,154,161,163,177,190,193,194,199,206,207,212,216,231,230,232,237,240,238,245,267,281,289,300,302,304,311,334,362,359,364,371,366,382,386,390,394,411,405,408,432,435,...
589,1663,881,2083,1618,1437,1326,1699,190,1062,405,1216,432,2009,386,539,1968,0,483,289,2218,2049,366,2219,769,88,454,2134,31,2305,238,508,2444,1372,557,267,7,90,628,1671,143,1118,1796,1220,2786,394,1405,216,525,1186,1187,448,2012,2967,408,1746,1292,154,497,161,302,2447,1829,3117,829,793,1123,2891,3097,8,120,240,2228,1...
0.6667202646970376,-0.10377915671823269,0.3548007225100377,-0.31145474882693824,-0.0835841298387108,0.015900464346774338,0.07442888489169129,-0.12407556372432456,1.6937468932790258,0.2264292404709339,0.9705669749994547,0.1321121623528798,0.9241840457318883,-0.26906464190792506,1.0163834713233377,0.7327378977030797,-0.2...
3,376
Abnormality of the vasculature of the eye
24
70
3.461621
0.000537
P06865,P00846,P28070,P04439,Q9NSE4,P38435,Q9Y4P3,P03886,P21964,P02786,P04066,Q14739,P06280,Q9NZJ7,P35250,P10619,P07602,Q9C0D9,P16278,P17900,Q9NW15,Q13510,O75306,Q9NZ08
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
262,7,138,273,403,148,276,24,409,407,291,428,310,444,315,68,333,221,93,353,362,111,367,127
1662,1398,1510,2398,2359,3267,367,2752,3016,2853,7,407,24,291,273,2558,310,262,333,1185,2787,68,1331,2264,93,353,2486,1925,2089,918,409,2091,138,2680,2450,2642,1976,315,1706,2365,148,3098,1299,2453,1982,2057,3054,1158,949,111,3201,428,973,758,2197,932,712,2506,487,1906,1566,1500,221,1210,403,362,127,444,2988,276
-0.10377915671823269,0.03550516234149863,-0.023598660010764588,-0.4633615537366067,-0.44131505481374056,-1.4833391917688719,1.0616453881949772,-0.6672254158451334,-0.9059924038468624,-0.7611195948253038,3.576464581247993,0.9705669749994547,3.214321038100156,1.2941363054249848,1.3361396976874031,-0.552738738110152,1.208...
3,376
Liposaccharide metabolic process
9
17
3.458407
0.000543
Q16739,P04066,Q99805,Q8NBX0,P06865,Q9NZD2,P06280,P04062,P16278
Processes and pathways
GO Biological process
msigdb_gobp
64,291,196,166,262,210,310,90,93
1668,90,291,310,262,1185,93,353,1303,64,166,1273,1355,934,196,878,210
-0.10377915671823269,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,0.15115574181980668,2.470216891564265,1.1063642295621396,0.09374950248621658,2.7127698952516086,1.8418778252097934,0.11297700392516687,0.07442888489169129,0.3367165517731276,1.6684451556620152,0.372801821409757,1.56540566205...
3,376
Predicted secreted proteins
20
59
3.454403
0.000552
Q08380,P43490,O00584,O60888,P80303,P04083,P05067,Q9Y4P3,Q15165,P84157,P02786,Q9UM22,Q9HB40,Q8N128,Q8WXW3,Q8NDZ4,O94919,Q02818,Q92520,Q9NZ08
Functions
Protein Atlas Protein class
protein_atlas_protein_class
257,1,252,132,4,393,143,276,21,279,407,43,55,195,465,217,225,242,125,127
252,1741,132,568,1578,225,407,393,143,1875,2786,2360,1029,3135,677,1703,659,2894,1410,1832,1,922,2320,3361,812,991,4,2370,279,242,948,257,1890,896,1200,21,1846,2581,195,1770,3106,217,3279,465,125,1904,1534,1358,855,477,2909,2172,1911,55,127,1365,43,788,276
1.4050887812930244,-0.14447423395217424,2.075654841379259,0.6998715023470454,-0.0634896107921604,1.4994697838784592,0.9705669749994547,1.0011735038559333,2.018667073067943,-0.20629282062173515,-0.6905032048336213,-0.44131505481374056,0.2450260771368476,-1.1071432230243936,0.565514082039327,-0.12407556372432456,0.582567...
3,376
Protein localization to mitochondrion
31
64
3.448501
0.000564
O60830,Q9NS69,Q99595,P55786,Q9P0J0,Q5JRX3,Q9Y512,O43615,Q9Y371,P49257,O14737,O96008,P52789,Q8N4H5,Q96EP0,O14925,P0DP25,Q9GZY8,Q15388,Q9Y5J9,O43464,O95140,Q10713,Q9Y6C9,O00165,O00170,Q96DA6,Q53H12,P49840,Q15070,Q8TB36
Processes and pathways
GO Biological process
msigdb_gobp
0,2,3,145,283,412,416,405,685,679,298,557,304,54,571,190,448,327,206,737,590,723,608,490,602,482,624,744,364,243,761
602,482,2046,826,298,190,590,405,0,2219,2305,723,3233,1743,1372,557,1092,448,2967,2639,2448,2834,2310,2268,1881,2187,679,364,1154,304,145,2098,608,1303,243,206,2535,833,744,412,2335,54,2422,761,762,624,571,3,2115,1601,327,1856,2,2545,283,2390,3095,1613,685,416,1146,737,1147,490
0.6500364914113959,0.8296696426224738,-0.2902048261296045,0.4085574264207841,1.2373723709299225,1.6937468932790258,0.6667202646970376,0.9705669749994547,4.625302186087037,-0.37587289727828466,-0.41938548886236693,0.5138974074088837,-1.3452365310224934,-0.14447423395217424,0.055014368762545285,0.7163400404236764,0.20774...
3,376
Lytic vacuole organization
9
28
3.444461
0.000572
P54802,Q14108,Q8N511,O75503,Q9HC07,P50897,P10253,O14773,P04062
Processes and pathways
GO Biological process
msigdb_gobp
121,37,40,137,112,22,182,25,90
2046,25,137,770,90,1185,182,197,1224,22,2318,121,1677,335,37,2693,1812,1949,40,1906,522,1853,856,112,3111,656,824,1086
-0.2902048261296045,3.190224570239214,2.0415749265642926,0.4615839958458578,2.4902865084460193,0.15115574181980668,1.7685881177452407,1.655726557404686,0.1321121623528798,3.2302833584863713,-0.41938548886236693,2.1649209674192837,-0.10377915671823269,1.135880610204166,3.050094664845848,-0.6210539026805592,-0.1649760614...
3,376
Establishment of protein localization to membrane
44
96
3.416632
0.000634
O43681,A5D8V6,Q9NS69,O15027,Q5J8M3,Q9HD20,Q7L5D6,P46379,Q8N4V1,Q8N3F8,Q9P0J0,Q9H9H4,Q9Y512,Q9NT62,O15118,P43307,P27105,Q9P0I2,Q15904,O14737,Q15629,Q15836,O00560,Q9UGP8,P49069,Q15041,P0DP25,Q9GZY8,O43765,Q9Y5J9,Q9H4A6,P40855,Q4J6C6,Q99442,Q96A33,Q53H12,P31751,Q9H2M9,P49458,Q15070,Q9HD26,Q8WWC4,P50542,O60725
Processes and pathways
GO Biological process
msigdb_gobp
506,379,2,627,519,135,521,140,19,275,283,415,416,806,157,34,163,684,295,298,50,436,446,719,569,570,448,327,703,737,213,591,732,476,346,744,232,365,493,243,501,762,382,126
379,1866,2046,446,298,627,157,2884,506,703,126,1791,2753,2305,1873,1671,1092,2887,448,163,2310,2186,232,2187,2312,591,1479,34,140,1980,569,493,382,2318,3037,3069,2611,2020,797,2568,2324,1262,1381,1987,2530,1039,2280,1760,2694,570,2283,243,50,436,295,732,1844,744,519,521,1950,2873,275,19,1849,1310,762,346,1853,476,856,3...
1.0315318217278158,-0.20629282062173515,-0.2902048261296045,0.8929413902574874,1.2373723709299225,0.6164499083295459,1.9136707952245202,-0.784923636467135,0.7815125855528189,0.5311795854762361,2.1094015983677914,-0.16497606147263494,-0.6672254158451334,-0.41938548886236693,-0.20629282062173515,-0.10377915671823269,0.20...
3,376
Protein targeting to mitochondrion
26
51
3.415318
0.000637
O60830,Q9NS69,Q99595,P55786,Q9P0J0,Q5JRX3,Q9Y512,O43615,Q9Y371,P49257,O14737,O96008,Q8N4H5,Q96EP0,O14925,Q9GZY8,Q15388,Q9Y5J9,O43464,O95140,Q10713,O00165,O00170,Q96DA6,Q53H12,P49840
Processes and pathways
GO Biological process
msigdb_gobp
0,2,3,145,283,412,416,405,685,679,298,557,54,571,190,327,206,737,590,723,608,602,482,624,744,364
602,482,298,190,590,405,0,2219,2305,723,3233,1743,1372,557,1092,2967,2834,2268,2187,679,364,1154,145,2098,608,1303,206,2535,833,744,412,2335,54,2422,761,624,571,3,2115,1601,327,1856,2,283,2390,3095,685,416,1146,737,1147
0.6500364914113959,0.8296696426224738,1.2373723709299225,1.6937468932790258,0.6667202646970376,0.9705669749994547,4.625302186087037,-0.37587289727828466,-0.41938548886236693,0.5138974074088837,-1.3452365310224934,-0.14447423395217424,0.055014368762545285,0.7163400404236764,0.2077445134366247,-0.8571497916635558,-0.7374...
3,376
Ceramide metabolic process
13
22
3.381135
0.000722
Q16739,P17900,Q99805,Q9NRA0,P06865,Q96G23,O95470,O15121,P30153,Q13510,Q8NCC3,P06280,P04062
Processes and pathways
GO Biological process
msigdb_gobp
64,353,196,489,262,167,265,123,268,111,85,310,90
123,491,1868,590,265,90,310,262,1185,353,268,1303,111,64,744,85,167,196,489,2120,1173,825
2.1428207883227306,0.8136850803085195,-0.20629282062173515,0.6667202646970376,1.3638760848112592,2.4902865084460193,1.208658359818944,1.3776655599934584,0.15115574181980668,1.1063642295621396,1.3500342456184196,0.09374950248621658,2.315743939212719,2.7127698952516086,0.4965378185069035,2.5497809452946028,1.841877825209...
3,376
Membrane lipid biosynthetic process
11
24
3.372588
0.000745
Q16739,Q06136,Q99805,Q9NRA0,Q8NBX0,Q96G23,O95470,O15121,Q13510,Q9P035,P04062
Processes and pathways
GO Biological process
msigdb_gobp
64,98,196,489,166,167,265,123,111,481,90
123,491,1868,1668,265,90,1750,98,1303,111,64,744,166,1273,1355,167,934,196,878,489,2120,1173,481,2435
2.1428207883227306,0.8136850803085195,-0.20629282062173515,-0.10377915671823269,1.3638760848112592,2.4902865084460193,-0.14447423395217424,2.429712971519325,0.09374950248621658,2.315743939212719,2.7127698952516086,0.4965378185069035,1.8418778252097934,0.11297700392516687,0.07442888489169129,1.8418778252097934,0.3367165...
3,376
Organic anion transmembrane transporter activity
18
33
3.371058
0.000749
P11166,Q6NUK1,P30825,O95563,P53985,Q9H2D1,Q8TB61,O75746,Q86VD7,Q9BQT8,Q9UBX3,Q6KCM7,Q9UJS0,Q9HC21,P12236,P08195,Q9Y619,P12235
Functions
GO Molecular function
msigdb_gomf
408,780,56,508,199,42,109,769,177,533,83,212,642,438,497,525,675,154
1699,1062,2009,769,508,1118,525,408,154,497,56,2722,773,199,1158,1201,1384,212,780,2196,177,109,1532,533,42,1138,1604,438,83,642,1658,675,861
-0.12407556372432456,0.2264292404709339,-0.26906464190792506,0.4615839958458578,0.7815125855528189,0.18897117543040606,0.7490655969974919,0.9705669749994547,1.9607270744213334,0.7976328933322394,2.7958932046881895,-0.6440760551569396,0.4615839958458578,1.6429624336734927,0.17010849742073567,0.15115574181980668,0.055014...
3,376
Steroid binding
8
21
3.368199
0.000757
Q14108,P21796,O15173,P45880,P38435,Q14849,P04062,O15118
Functions
GO Molecular function
msigdb_gomf
37,8,72,11,148,58,90,157
277,157,72,1217,1794,90,628,1405,8,1750,1254,2268,1068,148,11,812,37,58,1020,1820,3239
1.322192093055503,1.9136707952245202,2.637070673082067,0.1321121623528798,-0.16497606147263494,2.4902865084460193,0.6164499083295459,0.03550516234149863,3.555036482266552,-0.14447423395217424,0.11297700392516687,-0.3975717877794668,0.2264292404709339,1.9956068751611455,3.4381474194828905,0.42631322556594947,3.050094664...
3,376
Organic acid transmembrane transport
18
33
3.36169
0.000775
P33121,P11166,O95563,P53985,P50416,O75915,Q9H2D1,O60831,P31751,P23786,O43772,Q9BQT8,Q9UBX3,Q9UJS0,P08195,P30825,P08183,Q15041
Processes and pathways
GO Biological process
msigdb_gobp
630,408,508,199,359,454,42,483,232,120,432,533,83,642,525,56,216,570
1326,432,483,769,454,508,1796,216,525,408,120,2015,56,232,630,2722,359,773,199,1158,570,1384,1044,1532,533,42,3166,1138,1604,83,642,1658,675
0.07442888489169129,0.9241840457318883,0.8296696426224738,0.4615839958458578,0.8772224665898438,0.7815125855528189,-0.16497606147263494,1.5391760995751391,0.7490655969974919,0.9705669749994547,2.1649209674192837,-0.26906464190792506,2.7958932046881895,1.4727539894057913,0.6164499083295459,-0.6440760551569396,1.09151759...
3,376
Glycosphingolipid metabolism
11
16
3.35655
0.000789
Q16739,P17900,P10619,P06865,Q13510,Q9NZD2,P07602,P06280,Q9NZJ7,P04062,P16278
Processes and pathways
Reactome Pathways
msigdb_reactome
64,353,68,262,111,210,333,310,444,90,93
1661,506,90,310,262,333,1185,68,93,353,111,64,1728,1173,210,444
-0.10377915671823269,0.7815125855528189,2.4902865084460193,1.208658359818944,1.3776655599934584,1.135880610204166,0.15115574181980668,2.67513802823974,2.470216891564265,1.1063642295621396,2.315743939212719,2.7127698952516086,-0.12407556372432456,0.17010849742073567,1.56540566205142,0.9085950944992713
3,376
Intrinsic component of mitochondrial inner membrane
23
33
3.344944
0.000823
O60830,Q99595,O95563,O43819,O75431,Q9NX63,Q9NVH1,Q9Y512,O75880,Q8NE86,Q9HC21,Q9Y2R0,O14925,Q13505,Q5XKP0,Q9P0S2,Q9BUR5,Q16891,Q9H3K2,Q6P4A7,Q6UXV4,Q53H12,Q15070
Localization
GO Cellular component
msigdb_gocc
0,3,508,886,392,671,669,416,290,820,438,61,190,76,849,214,477,731,354,230,870,744,243
190,886,0,392,290,508,3127,1300,76,243,925,731,744,1683,849,230,870,820,1532,3,477,354,1604,2590,438,669,671,214,1366,61,1659,416,1215
1.6937468932790258,0.3548007225100377,4.625302186087037,1.0011735038559333,1.2941363054249848,0.7815125855528189,-1.0814780591807345,0.09374950248621658,2.598559042970186,1.445839319599628,0.3367165517731276,0.5138974074088837,0.4965378185069035,-0.10377915671823269,0.3907205059965324,1.486136587048457,0.37280182140975...
3,376
Abnormality of head blood vessel
14
24
3.342939
0.000829
P17900,P10619,P06865,P00846,Q9C0D9,P48651,Q13510,Q9Y4P3,P07602,P03886,Q9NZJ7,P35250,P16278,P21964
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
353,68,262,7,221,241,111,276,333,24,444,315,93,409
1398,2047,7,24,262,333,1185,68,2264,93,353,409,315,241,2057,3054,111,973,2506,487,221,444,2988,276
0.03550516234149863,-0.2902048261296045,3.576464581247993,3.214321038100156,1.3776655599934584,1.135880610204166,0.15115574181980668,2.67513802823974,-0.3975717877794668,2.470216891564265,1.1063642295621396,0.9705669749994547,1.1942170327352566,1.445839319599628,-0.2902048261296045,-0.9554014328962437,2.315743939212719...
3,376
Proton transmembrane transporter activity
11
36
3.32089
0.000897
P13073,Q13423,P00846,Q9Y487,Q9UDW1,P00403,P24539,O95202,P12235,Q93050,O75964
Functions
GO Molecular function
msigdb_gomf
161,194,7,423,74,267,240,238,154,188,31
1437,2134,31,238,267,7,1118,1220,1186,2012,154,161,793,1123,2891,240,2228,889,2143,1411,1798,2316,3086,1096,968,456,1300,194,1344,1386,188,1138,74,911,423,2081
0.015900464346774338,-0.33281539857511017,3.091955963388661,1.445839319599628,1.3500342456184196,3.576464581247993,0.18897117543040606,0.1321121623528798,0.15115574181980668,-0.26906464190792506,1.9607270744213334,1.8659724939578621,0.4439885391534624,0.18897117543040606,-0.784923636467135,1.445839319599628,-0.37587289...
3,376
Mitochondrial membrane organization
28
50
3.31177
0.000927
Q9NS69,P45880,O75431,Q9NX63,Q9P0J0,Q9NVH1,Q9Y512,P12235,O14737,Q8IWA4,P52789,Q3ZCQ8,P0DP25,P49841,Q13505,O60313,Q9Y5J9,Q5XKP0,Q9BUR5,Q16891,O95140,Q9H3K2,Q53H12,P49840,Q15070,O95202,Q8WWC4,P50542
Processes and pathways
GO Biological process
msigdb_gobp
2,11,392,671,283,669,416,154,298,819,304,833,448,330,76,329,737,849,477,731,723,354,744,364,243,238,762,382
2046,298,329,392,2305,723,238,1473,1118,1092,1745,448,154,2994,2310,2187,3127,2644,11,1376,364,330,382,304,76,243,2933,731,833,744,1683,849,870,819,1848,1897,762,477,354,2,669,671,283,3095,1613,1659,416,1146,737,1147
-0.2902048261296045,1.2373723709299225,1.1505511630774563,1.0011735038559333,-0.41938548886236693,0.5138974074088837,1.445839319599628,-0.0038005361770060086,0.18897117543040606,0.2077445134366247,-0.14447423395217424,0.8929413902574874,1.9607270744213334,-0.8815009988157699,-0.41938548886236693,-0.354287776657499,-1.0...
3,376
Outer membrane
33
95
3.306127
0.000946
Q9NS69,P21796,P45880,O75431,P09601,O43169,Q96RL7,Q8WY22,Q96TC7,O00264,Q9Y512,P50402,Q7Z434,P57105,Q9NZ45,Q07820,P52789,Q8N4H5,Q9BWH2,Q8WWI5,Q9NZJ7,Q6NUM9,Q9GZY8,Q13505,O60313,Q15388,Q9UBF8,Q9BUR5,Q99720,Q86UT6,Q9Y277,P50416,Q9HCL2
Localization
GO Cellular component
msigdb_gocc
2,8,11,392,15,18,146,20,152,277,416,417,419,427,46,435,304,54,312,443,444,323,327,76,329,206,469,477,96,345,231,359,117
602,277,826,3369,18,329,1063,392,2305,723,1873,557,1404,2756,1745,15,2448,8,2268,630,3127,1224,2837,11,417,359,304,2972,427,990,435,894,76,2899,206,2535,2933,731,744,1683,2657,849,323,610,870,419,345,819,997,1848,1897,930,54,2109,1310,761,443,1104,2290,20,2166,3329,2339,146,152,551,1208,96,1360,477,3257,312,2540,2068,3...
0.6500364914113959,1.322192093055503,0.4085574264207841,-5.788717024452099,3.2933320299293305,1.1505511630774563,0.2264292404709339,1.0011735038559333,-0.41938548886236693,0.5138974074088837,-0.20629282062173515,0.7163400404236764,0.03550516234149863,-0.6672254158451334,-0.14447423395217424,3.3779946752279097,-0.485526...
3,376
Protease
22
83
3.283334
0.001026
P07384,P67812,P55786,Q15005,Q5JRX3,O14773,O75976,Q9UIQ6,Q96FZ2,P28072,Q9HB40,Q99538,P52888,P10619,Q9H3G5,O75844,P42785,Q96BN8,P42892,Q16740,Q8TCT9,Q9NZ08
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
394,13,145,280,412,25,406,309,308,179,55,184,441,68,73,88,101,488,118,376,514,127
1505,1285,25,590,1574,2219,88,406,2679,725,394,1406,68,2605,1703,3268,179,687,3243,1631,2230,2489,101,118,1193,1375,921,2839,441,1801,1483,145,13,2370,2497,2616,280,376,732,412,634,2795,1993,1846,2286,595,1103,2462,1527,514,1273,851,2507,1392,488,1597,308,763,2206,1357,2385,1134,2803,184,2115,1080,73,2172,1393,515,55,1...
-0.023598660010764588,0.09374950248621658,3.190224570239214,0.6667202646970376,-0.0634896107921604,-0.37587289727828466,2.5201665300557425,0.9705669749994547,-0.6210539026805592,0.5138974074088837,1.0011735038559333,0.03550516234149863,2.67513802823974,-0.5753864237832664,-0.12407556372432456,-1.4833391917688719,1.7809...
3,376
SLC25 family of mitochondrial transporters
17
23
3.279729
0.001039
Q6NUK1,Q9Y6C9,P12236,Q9H2D1,O75746,O43772,Q86VD7,Q9BQT8,Q9UBX3,Q6KCM7,Q70HW3,Q9HC21,Q9UJS0,Q9NZJ7,Q9Y619,P12235,Q9BSK2
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
780,490,497,42,769,432,177,533,83,212,113,438,642,444,675,154,28
432,2009,769,1118,154,497,773,1300,1158,212,780,113,177,533,28,42,1138,438,444,83,642,675,490
0.9241840457318883,-0.26906464190792506,0.4615839958458578,0.18897117543040606,1.9607270744213334,0.7976328933322394,0.4615839958458578,0.09374950248621658,0.17010849742073567,1.552314809182681,0.4615839958458578,2.262642140545865,1.7931876481313542,0.7490655969974919,3.1496497632836333,2.990550171469064,0.188971175430...
3,376
Mitochondrial carrier domain superfamily [IPR023395]
17
23
3.279729
0.001039
Q6NUK1,Q9Y6C9,P12236,Q9H2D1,O75746,O43772,Q86VD7,Q9BQT8,Q9UBX3,Q6KCM7,Q70HW3,Q9HC21,Q9UJS0,Q9NZJ7,Q9Y619,P12235,Q9BSK2
Sequence
InterPro Superfamily
interpro_homologous_superfamily
780,490,497,42,769,432,177,533,83,212,113,438,642,444,675,154,28
432,2009,769,1118,154,497,773,1300,1158,212,780,113,177,533,28,42,1138,438,444,83,642,675,490
0.9241840457318883,-0.26906464190792506,0.4615839958458578,0.18897117543040606,1.9607270744213334,0.7976328933322394,0.4615839958458578,0.09374950248621658,0.17010849742073567,1.552314809182681,0.4615839958458578,2.262642140545865,1.7931876481313542,0.7490655969974919,3.1496497632836333,2.990550171469064,0.188971175430...
3,376
Mitochondrial substrate/solute carrier [IPR018108]
17
23
3.279729
0.001039
Q6NUK1,Q9Y6C9,P12236,Q9H2D1,O75746,O43772,Q86VD7,Q9BQT8,Q9UBX3,Q6KCM7,Q70HW3,Q9HC21,Q9UJS0,Q9NZJ7,Q9Y619,P12235,Q9BSK2
Sequence
InterPro Repeat
interpro_repeat
780,490,497,42,769,432,177,533,83,212,113,438,642,444,675,154,28
432,2009,769,1118,154,497,773,1300,1158,212,780,113,177,533,28,42,1138,438,444,83,642,675,490
0.9241840457318883,-0.26906464190792506,0.4615839958458578,0.18897117543040606,1.9607270744213334,0.7976328933322394,0.4615839958458578,0.09374950248621658,0.17010849742073567,1.552314809182681,0.4615839958458578,2.262642140545865,1.7931876481313542,0.7490655969974919,3.1496497632836333,2.990550171469064,0.188971175430...
3,376
Organophosphate ester transport
10
29
3.270252
0.001075
Q8WTV0,Q14108,Q9H2D1,Q8TB61,Q96GC9,Q86VD7,Q9NZD2,Q6KCM7,P12235,Q9BSK2
Processes and pathways
GO Biological process
msigdb_gobp
130,37,42,109,144,177,210,212,154,28
1737,1062,2009,1118,216,154,497,1750,1254,2722,2368,812,621,37,743,212,780,177,109,1044,130,144,28,3239,42,438,210,2435,825
-0.14447423395217424,0.2264292404709339,-0.26906464190792506,0.18897117543040606,1.5391760995751391,1.9607270744213334,0.7976328933322394,-0.14447423395217424,0.11297700392516687,-0.6440760551569396,-0.44131505481374056,0.42631322556594947,0.6332798897464621,3.050094664845848,0.4965378185069035,1.552314809182681,0.4615...
3,376
Cytochrome complex assembly
8
16
3.267248
0.001086
O75880,Q69YU5,Q15070,P53701,Q9P0S2,Q9BSK2,Q9Y2R0,Q6DKK2
Processes and pathways
GO Biological process
msigdb_gobp
290,6,243,246,214,28,61,253
886,290,2316,246,243,1344,6,253,1386,420,957,1459,28,214,1613,61
0.3548007225100377,1.2941363054249848,-0.41938548886236693,1.418723201036815,1.445839319599628,0.07442888489169129,3.6468202246377133,1.4050887812930244,0.055014368762545285,0.9551695312607196,0.3185486441921405,0.015900464346774338,3.1496497632836333,1.552314809182681,-0.0634896107921604,2.749974815920368
3,376
Transport of small molecules
50
155
3.256582
0.001128
P35613,Q8WTV0,Q9HD20,P21796,P25787,P28070,P45880,P09601,Q8N4V1,Q13555,P55011,P35670,P08195,P12235,O15118,P02786,P11166,P30519,O75027,P27105,Q15904,Q9UBV2,Q9Y487,Q9BUN8,P16615,P28072,Q8WWI5,P30825,P51798,Q93050,Q9C0H2,P61289,P10644,P63218,P53985,P61421,Q9UBX3,Q14997,P08183,P49721,Q9Y277,Q9NW15,Q8TB61,Q70HW3,P20618,O9520...
Processes and pathways
Reactome Pathways
msigdb_reactome
256,130,135,8,263,138,11,15,19,528,411,526,525,154,157,407,408,33,289,163,295,296,423,430,302,179,443,56,311,188,63,450,317,457,199,456,83,211,216,99,231,362,109,113,239,238,244,503,497,384
701,2440,2808,1285,2301,157,1062,1330,289,2219,1217,1090,3017,1794,2915,238,2754,407,628,1671,1118,2051,1972,216,525,1876,15,317,408,154,497,1747,302,2447,1829,1628,829,2054,239,1123,2891,3199,8,543,263,2090,2720,163,1880,138,179,687,2015,33,1445,56,1704,1068,2229,2607,256,526,2721,1705,1411,2922,1798,591,1296,11,1032,...
0.5311795854762361,-0.4855260677859258,-0.7139106589140215,0.09374950248621658,-0.41938548886236693,1.9136707952245202,0.2264292404709339,0.07442888489169129,1.2941363054249848,-0.37587289727828466,0.1321121623528798,0.2077445134366247,-0.9059924038468624,-0.16497606147263494,-0.808862463451572,1.445839319599628,-0.667...
3,376
Oxidative phosphorylation
17
61
3.243946
0.001179
P13073,P00846,Q9Y487,Q15904,Q9UDW1,P00403,Q86Y39,O96000,O95168,P24539,O75306,O14949,P03886,O43676,Q93050,P14406,O75964
Processes and pathways
KEGG Pathways
msigdb_kegg
161,7,423,295,74,267,187,272,278,240,367,87,24,26,188,62,31
1618,1437,87,2716,26,1028,2049,367,1670,2134,31,278,704,2443,272,267,7,24,1220,1186,2012,161,62,3145,1189,2889,793,1123,2891,918,754,240,2228,2947,2450,889,2143,1411,1798,2316,3086,3226,1015,1096,968,2019,456,2842,295,2412,1895,1386,187,188,3159,74,911,423,2081,721,1215
-0.0835841298387108,0.015900464346774338,2.530067311521496,-0.6440760551569396,3.1659423425394335,0.2450260771368476,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,-0.33281539857511017,3.091955963388661,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,1.3500342456184196,3.5764645...
3,376
Mitochondrial protein import
18
36
3.224988
0.00126
O60830,Q10713,Q9NS69,Q99595,P21796,Q96DA6,Q13505,O75431,Q15388,O96008,Q9UJS0,Q8N4H5,P12236,Q5JRX3,Q9Y512,P12235,O43615,O14925
Processes and pathways
Reactome Pathways
msigdb_reactome
0,608,2,3,8,624,76,392,206,557,642,54,497,412,416,154,405,190
190,405,0,3205,392,2219,769,2305,557,1220,1186,2967,154,497,8,2228,3127,608,76,206,833,412,54,2422,624,3,2907,1856,2,671,642,1613,416,1146,737,1147
1.6937468932790258,0.9705669749994547,4.625302186087037,-1.2644156881924795,1.0011735038559333,-0.37587289727828466,0.4615839958458578,-0.41938548886236693,0.7163400404236764,0.1321121623528798,0.15115574181980668,-0.8571497916635558,1.9607270744213334,0.7976328933322394,3.555036482266552,-0.37587289727828466,-1.081478...
3,376
Exopeptidase activity
10
32
3.221482
0.001275
P10619,P42785,Q9H3G5,Q9UIQ6,P55786,Q9HB40,O75844,O14773,O75976,Q9NZ08
Functions
GO Molecular function
msigdb_gomf
68,101,73,309,145,55,88,25,406,127
25,88,406,407,1406,68,2605,3243,1631,1223,101,921,145,1099,2326,2497,1846,595,1103,745,785,1274,2206,1726,73,2172,55,1606,1569,1781,127,309
3.190224570239214,2.5201665300557425,0.9705669749994547,0.9705669749994547,0.03550516234149863,2.67513802823974,-0.5753864237832664,-1.3725120489511942,-0.0835841298387108,0.1321121623528798,2.4092761099767857,0.3367165517731276,2.0071561264974758,0.2077445134366247,-0.41938548886236693,-0.5078096934092219,-0.185581951...
3,376
Abnormal retinal artery morphology
13
22
3.219018
0.001286
P17900,P10619,P06865,P00846,Q9C0D9,Q13510,Q9Y4P3,P07602,P03886,Q9NZJ7,P35250,P16278,P21964
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
353,68,262,7,221,111,276,333,24,444,315,93,409
1398,7,24,262,333,1185,68,2264,93,353,409,315,2057,3054,111,973,2506,487,221,444,2988,276
0.03550516234149863,3.576464581247993,3.214321038100156,1.3776655599934584,1.135880610204166,0.15115574181980668,2.67513802823974,-0.3975717877794668,2.470216891564265,1.1063642295621396,0.9705669749994547,1.1942170327352566,-0.2902048261296045,-0.9554014328962437,2.315743939212719,0.3002963271667747,-0.507809693409221...
3,376
Electron transport chain oxphos system in mitochondria
13
54
3.210587
0.001325
P13073,P00846,Q9UDW1,P12235,P00403,O96000,O95168,P24539,O14949,P03886,O43676,P14406,O75964
Processes and pathways
WikiPathways
msigdb_wp
161,7,74,154,267,272,278,240,87,24,26,62,31
1618,1437,87,2716,26,1028,2049,367,1670,290,2134,31,278,704,2443,272,267,7,24,1118,1220,2012,154,497,161,62,3145,1189,2889,793,918,754,240,2228,2947,2450,889,2143,2316,3086,3226,1015,1096,968,2019,1344,2412,1895,1386,74,3258,3095,721,1215
-0.0835841298387108,0.015900464346774338,2.530067311521496,-0.6440760551569396,3.1659423425394335,0.2450260771368476,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.2941363054249848,-0.33281539857511017,3.091955963388661,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,1.3500342...
3,376
Corneal opacity
20
50
3.197843
0.001385
Q9Y4P3,P35670,O43505,P04066,O43933,O96028,P06280,P35250,P10619,P40855,O75844,P04062,P16278,Q06136,Q13510,O95202,P53701,P51648,P50542,P08236
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
276,526,538,291,539,172,310,315,68,591,88,90,93,98,111,238,246,119,382,381
790,2047,538,2599,2552,539,1064,3082,1149,88,1923,238,172,2306,90,291,310,381,2052,68,93,2486,1925,315,526,591,382,119,1125,246,2407,3054,2152,2059,98,2373,111,973,1165,1720,780,1269,1563,2910,640,1249,2546,2988,700,276
0.4439885391534624,-0.2902048261296045,0.7327378977030797,-0.5753864237832664,-0.552738738110152,0.7327378977030797,0.2264292404709339,-1.0053883317133208,0.17010849742073567,2.5201665300557425,-0.22710959688583782,1.445839319599628,1.8176168745831065,-0.41938548886236693,2.4902865084460193,1.2941363054249848,1.2086583...
3,376
Hydrolase activity acting on glycosyl bonds
11
30
3.181482
0.001465
P17900,P04066,P06865,Q9NUJ1,O75503,O60502,P10253,P06280,P54802,P04062,P16278
Functions
GO Molecular function
msigdb_gomf
353,291,262,171,137,47,182,310,121,90,93
790,1666,47,137,90,291,310,262,1185,381,182,1331,2968,93,353,1335,2092,1255,2921,2055,121,708,2692,2456,610,855,171,2073,1657,1783
0.4439885391534624,-0.10377915671823269,2.9560208536056787,2.0415749265642926,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,0.15115574181980668,1.0315318217278158,1.7685881177452407,0.07442888489169129,-0.8571497916635558,2.470216891564265,1.1063642295621396,0.07442888489169129,-0.311454748...
3,376
Vacuole organization
25
57
3.177292
0.001487
Q9P253,O75503,Q96ED9,O75787,Q96GC9,P50897,O14773,Q9NT62,P53365,Q14108,Q9Y371,Q8N511,Q9ULC3,P16615,P10253,P11117,Q6UWE0,Q9H0U4,Q12768,P04062,O95140,Q9H2M9,Q9HC07,Q9UHD9,P54802
Processes and pathways
GO Biological process
msigdb_gobp
656,137,522,770,144,22,25,806,796,37,685,40,700,302,182,197,709,599,335,90,723,365,112,767,121
2046,25,2131,137,770,723,1743,90,2786,1185,182,197,302,2403,1224,1982,22,2318,796,121,1016,1677,1229,335,37,2693,2283,2330,1812,709,1949,871,40,1313,1906,1458,522,144,1853,856,599,1320,365,112,806,3111,656,767,700,1396,3286,824,685,1086,1735,3131,1144
-0.2902048261296045,3.190224570239214,-0.33281539857511017,2.0415749265642926,0.4615839958458578,0.5138974074088837,-0.14447423395217424,2.4902865084460193,-0.6905032048336213,0.15115574181980668,1.7685881177452407,1.655726557404686,1.2230433462408152,-0.4633615537366067,0.1321121623528798,-0.2480332200865538,3.2302833...
3,376
Sphingolipid biosynthetic process
10
18
3.17155
0.001516
Q16739,Q06136,Q99805,Q9NRA0,Q96G23,O95470,P04062,Q13510,Q9P035,O15121
Processes and pathways
GO Biological process
msigdb_gobp
64,98,196,489,167,265,90,111,481,123
123,491,1868,265,90,1750,98,1303,111,64,744,167,196,489,2120,1173,481,2435
2.1428207883227306,0.8136850803085195,-0.20629282062173515,1.3638760848112592,2.4902865084460193,-0.14447423395217424,2.429712971519325,0.09374950248621658,2.315743939212719,2.7127698952516086,0.4965378185069035,1.8418778252097934,1.6684451556620152,0.8296696426224738,-0.31145474882693824,0.17010849742073567,0.84558707...
3,376
Serine hydrolase activity
8
17
3.166233
0.001544
P10619,P42785,Q9H3G5,P67812,Q9HB40,Q16740,Q5JRX3,O14773
Functions
GO Molecular function
msigdb_gomf
68,101,73,13,55,376,412,25
25,590,406,68,1828,1631,2230,101,1375,1801,13,376,732,412,1103,73,55
3.190224570239214,0.6667202646970376,0.9705669749994547,2.67513802823974,-0.18558195150973228,-0.0835841298387108,-0.37587289727828466,2.4092761099767857,0.055014368762545285,-0.16497606147263494,3.4306920800070304,1.046618985345816,0.5138974074088837,0.9705669749994547,0.2077445134366247,2.617870951389883,2.8049997784...
3,376
Sphingolipid metabolism in senescence
6
14
3.163356
0.00156
Q16739,Q06136,O15121,Q13510,P04062,P16278
Processes and pathways
WikiPathways
msigdb_wp
64,98,123,111,90,93
123,491,90,1013,944,93,2447,794,1974,1224,98,111,64,167
2.1428207883227306,0.8136850803085195,2.4902865084460193,0.2635357357357556,0.3185486441921405,2.470216891564265,-0.4855260677859258,0.4439885391534624,-0.2480332200865538,0.1321121623528798,2.429712971519325,2.315743939212719,2.7127698952516086,1.8418778252097934
3,376
Tetrapyrrole binding
8
16
3.162618
0.001564
Q9NRV9,P30519,O15173,Q16850,P09601,Q6UW02,O43169,P53701
Functions
GO Molecular function
msigdb_gomf
160,33,72,141,15,176,18,246
277,72,18,1186,15,2759,33,246,141,176,1386,1956,597,459,160,2392
1.322192093055503,2.637070673082067,3.2933320299293305,0.15115574181980668,3.3779946752279097,-0.6672254158451334,3.083627658114699,1.418723201036815,2.030139933980146,1.7931876481313542,0.055014368762545285,-0.22710959688583782,0.6667202646970376,0.8772224665898438,1.8779580865773922,-0.44131505481374056
3,376
Horizontal nystagmus
9
25
3.147537
0.001647
Q9NW15,P00846,Q9H061,O60313,Q9NSE4,P50542,P07602,O14773,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
362,7,10,329,403,382,333,25,90
2046,826,25,1664,329,1794,1372,7,90,333,1926,1933,382,2896,2407,2492,1344,1167,2113,1692,10,403,362,444,1007
-0.2902048261296045,0.4085574264207841,3.190224570239214,-0.10377915671823269,1.1505511630774563,-0.16497606147263494,0.055014368762545285,3.576464581247993,2.4902865084460193,1.135880610204166,-0.22710959688583782,-0.22710959688583782,1.0315318217278158,-0.784923636467135,-0.4633615537366067,-0.5078096934092219,0.0744...
3,376
Protein transmembrane transport
15
28
3.146645
0.001652
O60830,Q9NS69,Q99595,P49755,O43933,P31751,Q15388,Q07820,O96008,Q15629,O75298,P50542,Q99442,O43615,O14925
Processes and pathways
GO Biological process
msigdb_gobp
0,2,3,485,539,232,206,435,557,50,366,382,476,405,190
190,405,539,0,366,2305,1372,557,2967,1746,232,485,382,3069,2020,2568,435,206,50,833,1950,2422,624,476,3,1856,2,719
1.6937468932790258,0.9705669749994547,0.7327378977030797,4.625302186087037,1.0616453881949772,-0.41938548886236693,0.055014368762545285,0.7163400404236764,-0.8571497916635558,-0.14447423395217424,1.4727539894057913,0.8296696426224738,1.0315318217278158,-0.980321919952045,-0.26906464190792506,-0.552738738110152,0.924184...
3,376
Splenomegaly
27
92
3.144081
0.001666
P08236,Q9BUR4,P28070,Q96RL7,P33991,O15118,P21964,P11166,P04066,Q14108,Q15904,Q14739,P00813,P10253,P51798,Q15392,P15586,P07602,P04062,P16278,Q96A33,P54802,Q6NUQ1,Q13510,Q9BT22,Q9H9E3,Q9NZ08
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
381,391,138,146,410,157,409,408,291,37,295,428,49,182,311,191,319,333,90,93,346,121,229,111,249,250,127
1398,2046,2257,790,2961,884,157,1668,3267,2218,1969,1184,1218,2719,49,2306,90,291,2518,1473,2558,1875,2785,333,381,182,408,2087,2446,1746,1292,2605,677,319,93,1093,2448,1094,1123,409,2759,3033,138,2015,1631,410,526,1223,2270,2922,1299,1982,1756,311,2057,2321,121,2897,812,1197,608,1302,111,1161,37,428,191,3072,1451,898,...
0.03550516234149863,-0.2902048261296045,-0.3975717877794668,0.4439885391534624,-0.8571497916635558,0.3548007225100377,1.9136707952245202,-0.10377915671823269,-1.4833391917688719,-0.37587289727828466,-0.2480332200865538,0.15115574181980668,0.1321121623528798,-0.6440760551569396,2.9211164682126753,-0.41938548886236693,2....
3,376
Sphingolipid metabolism
10
13
3.142168
0.001677
Q16739,Q06136,Q9NRA0,O95470,P04062,O15269,Q13510,P06280,O15121,P16278
Processes and pathways
KEGG Pathways
msigdb_kegg
64,98,489,265,90,491,111,310,123,93
123,491,1868,506,265,90,310,93,98,111,64,489,1173
2.1428207883227306,0.8136850803085195,-0.20629282062173515,0.7815125855528189,1.3638760848112592,2.4902865084460193,1.208658359818944,2.470216891564265,2.429712971519325,2.315743939212719,2.7127698952516086,0.8296696426224738,0.17010849742073567
3,376
Sterol metabolic process
11
38
3.128533
0.001757
Q8WTV0,P04035,Q14534,Q16850,P05067,Q9H2C2,Q15800,Q14849,P04062,O15118,Q15392
Processes and pathways
GO Biological process
msigdb_gobp
130,261,235,141,143,53,116,58,90,157,191
157,1217,1794,1404,261,90,143,1292,965,266,2893,1068,843,2922,2644,920,632,1802,2948,812,2653,2927,1303,2866,235,428,58,869,2284,191,1203,116,141,130,53,2546,2121,2780
1.9136707952245202,0.1321121623528798,-0.16497606147263494,0.03550516234149863,1.3776655599934584,2.4902865084460193,2.018667073067943,0.09374950248621658,0.3002963271667747,1.3638760848112592,-0.784923636467135,0.2264292404709339,0.3907205059965324,-0.808862463451572,-0.5981577547393172,0.3367165517731276,0.6164499083...
3,376
Ion transport
22
56
3.124729
0.00178
P05023,P00846,P21796,P45880,P55011,P35670,O75964,Q9Y487,Q15904,Q6P4Q7,P16615,O96008,P51798,Q93050,Q9C0H2,P61421,Q6PML9,Q9Y277,Q9NVV0,P24539,O95202,Q8NE01
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
628,7,8,11,411,526,31,423,295,300,302,557,311,188,63,456,594,231,237,240,238,245
881,2134,31,238,557,7,628,1671,1220,1187,302,829,1123,2891,8,240,2228,526,2143,1411,1798,11,3086,311,1337,411,1096,968,456,1262,1265,295,743,3356,300,594,245,820,1044,188,1500,654,3257,63,1362,3166,1543,237,911,2826,231,1658,423,2081,2550,861
0.3548007225100377,-0.33281539857511017,3.091955963388661,1.445839319599628,0.7163400404236764,3.576464581247993,0.6164499083295459,-0.10377915671823269,0.1321121623528798,0.15115574181980668,1.2230433462408152,0.4085574264207841,0.18897117543040606,-0.784923636467135,3.555036482266552,1.445839319599628,-0.375872897278...
3,376
Slc mediated transmembrane transport
11
21
3.105225
0.001901
P35613,P11166,P12236,P53985,Q8TB61,Q70HW3,Q9UBX3,P55011,Q8WWI5,P30825,P12235
Processes and pathways
Reactome Pathways
msigdb_reactome
256,408,497,199,109,113,83,411,443,56,154
1118,525,408,154,497,1445,56,256,1705,199,411,1384,2196,113,109,443,3166,1138,83,1658,861
0.18897117543040606,0.7490655969974919,0.9705669749994547,1.9607270744213334,0.7976328933322394,0.015900464346774338,2.7958932046881895,1.3914030126962775,-0.12407556372432456,1.6429624336734927,0.9705669749994547,0.055014368762545285,-0.354287776657499,2.262642140545865,2.3262652314834207,0.9085950944992713,-1.1589358...
3,376
Primary active transmembrane transporter activity
15
58
3.09285
0.001982
P13073,O75027,P51798,Q9HD20,Q9UDW1,P00403,Q15388,O96000,O95168,Q03518,P16615,Q9P0J0,P03886,O43676,P08183
Functions
GO Molecular function
msigdb_gomf
161,289,311,135,74,267,206,272,278,334,302,283,24,26,216
1618,1437,1326,1062,2716,26,1028,289,2049,367,1670,278,704,2443,272,267,24,628,1671,1220,216,1186,2012,161,302,2889,829,793,1123,2891,2015,2947,889,526,1411,1798,2316,3226,311,1015,2019,456,1262,334,206,1344,2412,1895,1386,135,1732,1543,283,74,3258,911,2081,721
-0.0835841298387108,0.015900464346774338,0.07442888489169129,0.2264292404709339,-0.6440760551569396,3.1659423425394335,0.2450260771368476,1.2941363054249848,-0.2902048261296045,1.0616453881949772,-0.10377915671823269,1.322192093055503,0.5311795854762361,-0.4855260677859258,1.3361396976874031,1.3500342456184196,3.214321...
3,376
Circulatory system process
21
79
3.089036
0.002008
P09601,P55011,P02786,P11166,Q9UIQ6,P00813,P16615,P10253,Q9HB40,P30825,Q8WWI5,Q13464,P53985,O75844,P08183,P78417,P42785,P49840,Q9NVV0,P42892,Q9NZ08
Processes and pathways
GO Biological process
msigdb_gobp
15,411,407,408,309,49,302,182,55,56,443,322,199,88,216,94,101,364,237,118,127
826,2257,1699,1062,1741,1400,1970,770,88,3017,1578,2602,1404,49,407,3221,1373,628,1671,216,1672,15,448,182,408,1746,1253,2991,3208,302,2447,1829,829,3097,2138,1930,1445,56,2722,1884,1224,101,118,1376,729,364,3292,1095,199,411,2235,3102,776,991,94,661,3070,2770,1038,322,2190,3228,2899,1384,1846,2196,800,443,1565,1817,32...
0.4085574264207841,-0.3975717877794668,-0.12407556372432456,0.2264292404709339,-0.14447423395217424,0.03550516234149863,-0.2480332200865538,0.4615839958458578,2.5201665300557425,-0.9059924038468624,-0.0634896107921604,-0.5753864237832664,0.03550516234149863,2.9211164682126753,0.9705669749994547,-1.2911901352871467,0.05...
3,376
Endoplasmic reticulum to golgi vesicle mediated transport
23
68
3.081
0.002063
O15027,Q15363,Q9P2W9,O14579,Q8IUR0,Q96PC5,Q9Y3B3,Q9HCU5,O95249,Q9BVK6,O95070,Q9H0U4,Q969X5,Q8NHH9,Q9Y3A6,Q13190,Q9Y282,Q15436,P49755,Q6NUQ1,Q9NR31,Q9HD26,Q9BSR8
Processes and pathways
GO Biological process
msigdb_gobp
627,5,29,657,307,178,57,328,201,332,204,599,339,208,615,474,97,486,485,229,625,501,638
2397,657,627,1740,1572,3196,1669,2303,2131,1514,204,201,2050,2221,2482,1030,1191,1836,679,485,1154,988,2813,2320,2057,2148,1711,1229,1841,831,474,2496,5,486,3072,1385,229,2332,307,208,1313,1354,1496,339,1498,178,1318,638,332,599,2386,328,501,625,1049,2435,29,2076,2778,2779,1610,97,939,615,57,2595,1026,1368
-0.4633615537366067,0.5825675708995396,0.6164499083295459,-0.14447423395217424,-0.0634896107921604,-1.2378047400733483,-0.10377915671823269,-0.41938548886236693,-0.33281539857511017,-0.023598660010764588,1.6043940725091548,1.630152502007486,-0.2902048261296045,-0.37587289727828466,-0.5078096934092219,0.2450260771368476...
3,376
Visual loss
16
47
3.074522
0.002108
Q8TC12,P51798,Q96JJ3,P00846,O75503,O00170,Q9NZJ7,O60313,P00403,P04439,O75306,P07602,P50897,P53701,P03886,O14773
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
583,311,585,7,137,482,444,329,267,273,367,333,22,246,24,25
1662,482,826,25,807,329,367,2219,137,1969,723,267,2181,7,24,2638,273,333,2011,2052,3116,1976,1706,2314,920,22,1756,311,1125,246,1069,2274,1987,608,2688,1488,3190,2498,1202,1526,583,1496,1421,585,3125,1249,444
-0.10377915671823269,0.8296696426224738,0.4085574264207841,3.190224570239214,0.42631322556594947,1.1505511630774563,1.0616453881949772,-0.37587289727828466,2.0415749265642926,-0.2480332200865538,0.5138974074088837,1.3500342456184196,-0.354287776657499,3.576464581247993,3.214321038100156,-0.5981577547393172,1.3361396976...
3,376
Hydrolase activity hydrolyzing o glycosyl compounds
10
22
3.073396
0.002116
P17900,P04066,P06865,Q9NUJ1,O60502,P10253,P06280,P54802,P04062,P16278
Functions
GO Molecular function
msigdb_gomf
353,291,262,171,47,182,310,121,90,93
790,47,90,291,310,262,1185,381,182,93,353,2921,2055,121,708,2692,2456,855,171,2073,1657,1783
0.4439885391534624,2.9560208536056787,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,0.15115574181980668,1.0315318217278158,1.7685881177452407,2.470216891564265,1.1063642295621396,-0.808862463451572,-0.2902048261296045,2.1649209674192837,0.5311795854762361,-0.6210539026805592,-0.485526067785...
3,376
Carbohydrate derivative catabolic process
14
34
3.063559
0.002187
Q13126,P17900,P04066,P15586,P06865,Q9H773,Q9NUJ1,P49840,O60502,P00813,P06280,P54802,P04062,P16278
Processes and pathways
GO Biological process
msigdb_gobp
32,353,291,319,262,9,171,364,47,49,310,121,90,93
940,47,2719,1549,49,90,291,310,262,1185,381,2968,319,93,353,2895,1975,2921,1068,3367,1981,364,1707,121,32,2702,1531,855,821,2670,9,171,1657,2300
0.3185486441921405,2.9560208536056787,-0.6440760551569396,-0.043494737915892735,2.9211164682126753,2.4902865084460193,1.2941363054249848,1.208658359818944,1.3776655599934584,0.15115574181980668,1.0315318217278158,-0.8571497916635558,1.179718982402758,2.470216891564265,1.1063642295621396,-0.784923636467135,-0.2480332200...
3,376
Glycosaminoglycan metabolism
7
15
3.061352
0.002203
P15586,P06865,Q8NCH0,Q8TB61,P54802,P16278,Q7LGA3
Processes and pathways
Reactome Pathways
msigdb_reactome
319,262,44,109,121,93,95
1027,538,964,262,1185,381,319,93,121,95,44,109,1565,1001,1212
0.2450260771368476,0.7327378977030797,0.3002963271667747,1.3776655599934584,0.15115574181980668,1.0315318217278158,1.179718982402758,2.470216891564265,2.1649209674192837,2.4398849348313916,2.973331959590957,2.3262652314834207,-0.043494737915892735,0.28195892039051096,0.15115574181980668
3,376