term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hedgehog off state
| 19
| 50
| 2.545699
| 0.010906
|
O00231,Q9UL46,P60900,Q99436,O43242,P61289,P49721,P28074,P68371,Q9BVA1,P49841,P10644,P20618,P04350,P63208,P28070,P49720,Q15008,P28072
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
251,147,408,164,533,436,56,54,312,458,327,448,202,333,470,225,230,499,373
|
251,1266,2221,1226,533,1640,333,448,839,1155,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,1124,230,56,327,557,994,408,436,845,1279,884,470,312,821,695,2269,618,2215,499,2408,898,164,1177,726,458,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.8614368152158327,0.6490043765907978,0.22708991471684983,-0.006127331605984542,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,0.020605480698360126,1.1365094929601929,2.4964247239663777,0.8819129546814536,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.9224673008330843,0.25201882658425456,0.3739010819588171,-1.1026963504909864,0.44490440798943937,-0.958720173237647,0.6047569844332618,-1.7863055278776567,0.20197116058474252,1.4232989777185565,-0.006127331605984542,0.34988503514948976,0.6490043765907978,1.5406396934742081,-0.06023936284890438
| 2,468
|
Degradation of dvl
| 13
| 37
| 2.545123
| 0.010924
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,793,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,0.27676037958362715,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Recruitment of numa to mitotic centrosomes
| 19
| 31
| 2.540432
| 0.011072
|
P41208,Q15154,P07437,P43034,Q15691,P68371,O95684,Q9BVA1,Q13561,P30153,P04350,Q9BUF5,P61981,Q13885,P63167,Q14203,P07900,O75935,Q9H6D7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
760,165,299,556,313,312,60,458,328,326,333,726,600,618,737,498,732,108,118
|
108,60,333,781,299,732,1155,326,760,556,1063,600,996,737,312,1622,328,618,1211,498,1213,2135,165,313,2078,1362,726,1180,458,118,1670
|
1.8373833245061917,2.43714387569957,0.8614368152158327,0.27676037958362715,0.9425484828699386,0.3256911134093675,-0.006127331605984542,0.8819129546814536,0.3013170110599651,0.5143859578494419,0.07343946733113242,0.4682311897943023,0.1254502957539166,0.3256911134093675,0.9224673008330843,-0.34455645734238355,0.8819129546814536,0.44490440798943937,-0.033074608598505244,0.6047569844332618,-0.033074608598505244,-0.8202718560579666,1.4061522919477702,0.9224673008330843,-0.7530070814189461,-0.1430695347463049,0.34988503514948976,-0.006127331605984542,0.6490043765907978,1.7621766159448307,-0.3743308591385381
| 2,468
|
Retinoblastoma gene in cancer
| 19
| 39
| 2.524166
| 0.011597
|
P25205,Q07864,Q14527,Q13547,P31350,P26583,P33991,Q00534,P09429,Q14566,P00374,P16949,P52701,P33993,P24941,P11802,Q16204,Q9UNN5,Q9Y619
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
633,526,267,676,523,395,405,421,319,452,79,213,348,468,224,223,234,381,125
|
908,1443,79,1758,781,319,1894,2241,223,982,1057,213,1156,224,633,985,395,1022,523,405,468,1763,989,1898,348,673,421,526,963,676,267,452,1583,234,1395,1398,381,1225,125
|
0.17666003360338126,-0.22797146657486117,2.1599235408173723,-0.46522306940850683,0.27676037958362715,0.9022559500015589,-0.590226648688484,-1.0299934512102915,1.1552498319919475,0.1254502957539166,0.07343946733113242,1.192389231232484,-0.006127331605984542,1.1552498319919475,0.42140856532916043,0.1254502957539166,0.7356968204452725,0.09954637705818221,0.5598892765754294,0.7142445586094798,0.6269572845849924,-0.46522306940850683,0.1254502957539166,-0.590226648688484,0.8200789823454424,0.3977415176858454,0.692646228876154,0.5598892765754294,0.15115395482942545,0.3977415176858454,1.0410518943199942,0.6490043765907978,-0.3150370549937861,1.1365094929601929,-0.17113556168396907,-0.17113556168396907,0.7781699552447922,-0.033074608598505244,1.6692773995529553
| 2,468
|
Glycosphingolipid metabolism
| 7
| 14
| 2.517614
| 0.011815
|
P04062,P10619,P06865,P16278,P06280,Q16739,P07602
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
236,81,209,18,339,92,31
|
1637,236,339,209,31,536,81,18,609,361,92,2015,1723,628
|
-0.3743308591385381,1.117653769245169,0.8408260074769911,1.2107906833937936,2.908601987092757,0.5372180454514659,2.1599235408173723,3.1754755052007098,0.44490440798943937,0.7991941651751763,2.024171009993822,-0.6869921898793442,-0.4043641190777143,0.44490440798943937
| 2,468
|
Nuclear outer membrane endoplasmic reticulum membrane network
| 70
| 252
| 2.515709
| 0.011879
|
Q8TB61,Q15629,P43307,P37268,P24390,Q8N511,P35610,P10321,Q10472,Q14739,Q9Y5M8,Q5H8A4,O95470,Q9BRR6,Q9BQE5,Q9Y282,Q15437,O15269,Q8N4V1,Q9P2W9,P30519,Q15904,Q9NZ01,O95864,O76062,Q9NZ08,Q86XL3,O75844,P35606,P55061,Q9Y678,O95197,O43852,Q16850,O60725,P63241,P67812,Q9HD20,Q6NUM9,Q8N0U8,Q15436,O95772,O00429,Q99720,Q8TCT9,Q96KC8,Q9Y4P3,Q15392,Q9UBU6,Q9NQC3,Q8TD16,Q14108,P35613,O15121,Q9BT22,Q07065,Q06136,Q8IV08,Q9Y3Q3,Q9Y3B3,P07099,Q15042,P62942,Q96G23,Q9UNN5,Q5BJF2,P16435,P49257,P31689,Q9BZF1
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,259,132,131,5,6,255,384,138,139,268,142,269,401,20,21,279,153,286,288,27,284,161,282,289,427,35,36,291,419,295,168,170,43,44,171,173,47,305,49,304,51,412,443,314,442,190,61,65,331,206,84,214,218,354,349,98,100,368,367,104,233,238,114,381,116,245,119,374,264
|
1049,570,412,778,1438,750,683,1568,808,836,1407,218,153,1725,170,505,952,44,2402,2086,1961,1412,36,2056,289,1192,1523,168,2239,269,1996,51,282,1683,1479,1231,1195,781,2198,104,1925,2116,522,384,1376,245,434,1447,1833,1574,1797,984,5,1646,2030,1237,1491,2033,27,1966,374,1835,291,255,214,131,1534,1697,1614,1578,132,734,881,493,691,119,762,692,1383,818,1309,1735,638,669,509,1126,843,1537,419,1699,671,2068,2318,2004,2304,1701,1738,1385,2399,2128,764,2130,238,1937,171,173,1454,2435,998,98,349,1619,138,1281,1741,1131,923,1623,84,1456,1503,541,139,1136,2136,1655,233,1979,698,61,304,279,259,2258,619,284,43,602,1390,116,142,2319,1847,1586,1879,305,2228,1141,1069,700,1356,1071,1812,35,858,100,2328,49,286,6,2229,893,1882,2141,1663,1038,1853,1001,128,1983,1393,2340,314,206,1854,1460,1855,2166,2311,895,896,724,2230,1142,897,1257,1430,114,624,1463,701,1289,442,647,1551,2410,969,443,1115,2274,20,401,1291,2015,354,1594,1717,1718,747,264,2249,863,1597,727,1886,1598,899,481,47,1145,1887,331,627,1723,161,427,482,1916,1821,288,748,942,65,681,2292,1560,1080,517,1563,381,21,1298,946,367,1473,368,190,268,1889,295,1918,654
|
0.07343946733113242,0.49139101679695213,0.692646228876154,0.27676037958362715,-0.22797146657486117,0.3013170110599651,0.3739010819588171,-0.3150370549937861,0.25201882658425456,0.22708991471684983,-0.1994350717264357,1.1738760097490326,1.4909169970454357,-0.4346601796282852,1.3541153522401639,0.58240161346863,0.15115395482942545,2.666835954385971,-1.742458928246437,-0.7864806683003362,-0.65444091817572,-0.1994350717264357,2.868122282262257,-0.7530070814189461,0.9625009483378237,-0.033074608598505244,-0.2857688748733796,1.3715614817905903,-1.0299934512102915,1.0216002256059087,-0.6869921898793442,2.5544363806012425,0.9823261264765617,-0.4043641190777143,-0.2567482190180186,-0.06023936284890438,-0.033074608598505244,0.27676037958362715,-0.9236044800386676,1.8815833993429565,-0.6221873063453945,-0.8202718560579666,0.5598892765754294,0.7570047251940325,-0.17113556168396907,1.0795911798832665,0.6709000913867084,-0.22797146657486117,-0.5271658967301447,-0.3150370549937861,-0.4960569056469889,0.1254502957539166,3.8314985860427604,-0.3743308591385381,-0.7198459356446938,-0.06023936284890438,-0.2567482190180186,-0.7198459356446938,2.928608323075618,-0.65444091817572,0.7781699552447922,-0.5271658967301447,0.9625009483378237,1.0603817720347808,1.192389231232484,1.6376421273678423,-0.2857688748733796,-0.4043641190777143,-0.34455645734238355,-0.3150370549937861,1.6376421273678423,0.3256911134093675,0.20197116058474252,0.6047569844332618,0.3739010819588171,1.7468979457042964,0.3013170110599651,0.3739010819588171,-0.17113556168396907,0.25201882658425456,-0.11523365842189977,-0.4346601796282852,0.42140856532916043,0.3977415176858454,0.58240161346863,0.020605480698360126,0.22708991471684983,-0.2857688748733796,0.692646228876154,-0.4043641190777143,0.3977415176858454,-0.7530070814189461,-1.2525962685132521,-0.6869921898793442,-1.214542773220608,-0.4043641190777143,-0.4346601796282852,-0.17113556168396907,-1.6562527119273847,-0.8202718560579666,0.3013170110599651,-0.8202718560579666,1.117653769245169,-0.6221873063453945,1.3541153522401639,1.3365673787376733,-0.22797146657486117,-2.3553677588654476,0.1254502957539166,1.9251128862095315,0.8200789823454424,-0.34455645734238355,1.6056618506283145,-0.08762466761145592,-0.4346601796282852,0.020605480698360126,0.17666003360338126,-0.34455645734238355,2.119881427808456,-0.22797146657486117,-0.2567482190180186,0.5372180454514659,1.6056618506283145,0.020605480698360126,-0.8202718560579666,-0.3743308591385381,1.1365094929601929,-0.65444091817572,0.3739010819588171,2.4130652487639477,0.9425484828699386,1.0020254240102997,1.0603817720347808,-1.066163090613305,0.44490440798943937,0.9823261264765617,2.7427903084146905,0.4682311897943023,-0.17113556168396907,1.7924944732535362,1.5895402794086952,-1.2525962685132521,-0.5271658967301447,-0.3150370549937861,-0.5585543448403263,0.9425484828699386,-0.994181179090294,0.020605480698360126,0.07343946733113242,0.3739010819588171,-0.1430695347463049,0.07343946733113242,-0.4960569056469889,2.8783012459093062,0.22708991471684983,1.9106764725104468,-1.2910471139088535,2.5886536324101614,0.9823261264765617,3.681490447648572,-0.994181179090294,0.20197116058474252,-0.5585543448403263,-0.8202718560579666,-0.3743308591385381,0.09954637705818221,-0.5271658967301447,0.1254502957539166,1.6535024833174539,-0.65444091817572,-0.17113556168396907,-1.3299025873109733,0.9224673008330843,1.2290815354843998,-0.5271658967301447,-0.22797146657486117,-0.5271658967301447,-0.8543859267849101,-1.214542773220608,0.20197116058474252,0.20197116058474252,0.34988503514948976,-0.994181179090294,0.020605480698360126,0.20197116058474252,-0.06023936284890438,-0.1994350717264357,1.807535106013106,0.44490440798943937,-0.22797146657486117,0.3739010819588171,-0.08762466761145592,0.6709000913867084,0.42140856532916043,-0.2857688748733796,-1.7863055278776567,0.15115395482942545,0.6709000913867084,0.047126781746465576,-1.1026963504909864,3.139012561494263,0.7356968204452725,-0.08762466761145592,-0.6869921898793442,0.8200789823454424,-0.3150370549937861,-0.4043641190777143,-0.4043641190777143,0.3256911134093675,1.0603817720347808,-1.0299934512102915,0.22708991471684983,-0.3150370549937861,0.34988503514948976,-0.5585543448403263,-0.3150370549937861,0.20197116058474252,0.6269572845849924,2.6224404188956902,0.020605480698360126,-0.5585543448403263,0.8819129546814536,0.44490440798943937,-0.4043641190777143,1.457299817470005,0.692646228876154,0.6269572845849924,-0.590226648688484,-0.4960569056469889,0.9823261264765617,0.3256911134093675,0.17666003360338126,2.351924388044598,0.3977415176858454,-1.139599641176551,-0.2857688748733796,0.07343946733113242,0.58240161346863,-0.2857688748733796,0.7781699552447922,3.129814463490708,-0.08762466761145592,0.17666003360338126,0.7991941651751763,-0.22797146657486117,0.7991941651751763,1.2833019254548965,1.0410518943199942,-0.5585543448403263,0.9625009483378237,-0.590226648688484,0.42140856532916043
| 2,468
|
C type lectin receptors clrs
| 16
| 45
| 2.515328
| 0.011892
|
P28070,O43865,O00231,Q99436,O43242,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P49427,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,505,251,164,533,230,202,499,373,147,436,56,407,408,470,54
|
251,1266,2221,1226,533,505,1640,1155,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,407,230,56,557,994,408,1540,1350,436,845,1279,884,470,821,1805,695,2269,2215,499,1287,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,0.58240161346863,-0.3743308591385381,-0.006127331605984542,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,0.7142445586094798,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,-0.2857688748733796,-0.1430695347463049,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,-0.4960569056469889,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,-0.08762466761145592,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Regulation of runx2 expression and activity
| 15
| 40
| 2.510942
| 0.012041
|
P28070,Q99436,O43242,O00231,P49720,P49841,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,327,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1382,1240,1093,230,56,327,557,994,408,436,845,1279,884,470,821,695,2269,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.17113556168396907,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.8819129546814536,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Threonine type endopeptidase activity
| 6
| 8
| 2.508926
| 0.01211
|
P28070,Q99436,P49720,P20618,P49721,P28074
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
225,164,230,202,56,54
|
202,1305,225,373,54,230,56,164
|
1.2290815354843998,-0.11523365842189977,1.1552498319919475,0.7781699552447922,2.4964247239663777,1.1365094929601929,2.4964247239663777,1.4232989777185565
| 2,468
|
Threonine type peptidase activity
| 6
| 8
| 2.508926
| 0.01211
|
P28070,Q99436,P49720,P20618,P49721,P28074
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
225,164,230,202,56,54
|
202,1305,225,373,54,230,56,164
|
1.2290815354843998,-0.11523365842189977,1.1552498319919475,0.7781699552447922,2.4964247239663777,1.1365094929601929,2.4964247239663777,1.4232989777185565
| 2,468
|
Proteasome beta-type subunit, conserved site [IPR016050]
| 6
| 8
| 2.508926
| 0.01211
|
P28070,Q99436,P49720,P20618,P49721,P28074
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
225,164,230,202,56,54
|
202,1305,225,373,54,230,56,164
|
1.2290815354843998,-0.11523365842189977,1.1552498319919475,0.7781699552447922,2.4964247239663777,1.1365094929601929,2.4964247239663777,1.4232989777185565
| 2,468
|
Fceri mediated nf kb activation
| 15
| 40
| 2.501628
| 0.012362
|
P28070,Q99436,O00231,O43242,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P49427,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,251,533,230,202,499,373,147,436,56,407,408,470,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,407,230,56,557,994,408,1350,436,845,1279,884,470,821,695,2269,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,0.7142445586094798,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,-0.1430695347463049,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Membrane lipid biosynthetic process
| 9
| 20
| 2.496795
| 0.012532
|
Q8NBX0,Q06136,P04062,Q5H8A4,Q99805,Q96G23,O15269,O15121,Q16739
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,98,236,142,180,114,153,218,92
|
218,153,269,236,1797,98,361,92,1105,142,33,895,2230,114,2410,180,1598,1723,482,1916
|
1.1738760097490326,1.4909169970454357,1.0216002256059087,1.117653769245169,-0.4960569056469889,1.9251128862095315,0.7991941651751763,2.024171009993822,0.047126781746465576,1.5895402794086952,2.908601987092757,0.20197116058474252,-0.994181179090294,1.807535106013106,-1.7863055278776567,1.3189165219976549,-0.3150370549937861,-0.4043641190777143,0.6269572845849924,-0.590226648688484
| 2,468
|
Respiratory failure
| 18
| 56
| 2.494444
| 0.012615
|
Q8NBU5,Q70HW3,Q14203,Q8TD16,P06753,Q9BT22,Q13510,Q86Y56,Q15165,O75306,P15924,P33991,Q9NSD9,P23786,Q92804,Q9Y619,P53701,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
262,3,498,206,447,354,361,335,48,371,404,405,316,26,189,125,96,31
|
1299,1191,371,2025,489,2239,447,31,1272,1893,1234,1196,404,2170,1379,1488,26,405,878,1275,1578,990,598,2036,1205,1277,96,1764,1699,2038,883,1842,361,498,48,586,1508,1943,1707,3,335,262,2142,206,1950,189,1858,354,831,1860,805,316,628,1917,868,125
|
-0.11523365842189977,-0.033074608598505244,0.7781699552447922,-0.7198459356446938,0.6047569844332618,-1.0299934512102915,0.6490043765907978,2.908601987092757,-0.08762466761145592,-0.590226648688484,-0.06023936284890438,-0.033074608598505244,0.7142445586094798,-0.8888282886905626,-0.17113556168396907,-0.2567482190180186,2.9583317443973955,0.7142445586094798,0.20197116058474252,-0.08762466761145592,-0.3150370549937861,0.1254502957539166,0.4682311897943023,-0.7198459356446938,-0.033074608598505244,-0.08762466761145592,1.9679892965036938,-0.46522306940850683,-0.4043641190777143,-0.7198459356446938,0.20197116058474252,-0.5271658967301447,0.7991941651751763,0.6047569844332618,2.5886536324101614,0.49139101679695213,-0.2567482190180186,-0.6221873063453945,-0.4043641190777143,4.09320199924866,0.8614368152158327,1.0603817720347808,-0.8202718560579666,1.2290815354843998,-0.6221873063453945,1.2833019254548965,-0.5271658967301447,0.8200789823454424,0.25201882658425456,-0.5271658967301447,0.27676037958362715,0.9224673008330843,0.44490440798943937,-0.590226648688484,0.22708991471684983,1.6692773995529553
| 2,468
|
Signaling by the b cell receptor bcr
| 16
| 41
| 2.491976
| 0.012703
|
P28070,Q99436,O43865,O00231,O43242,P49720,P20618,Q15008,P62942,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,505,251,533,230,202,499,238,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,505,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,238,2007,470,821,695,2269,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,0.58240161346863,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,1.117653769245169,-0.6869921898793442,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Stabilization of p53
| 13
| 37
| 2.488705
| 0.012821
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,1758,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,-0.46522306940850683,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Zinc ion binding
| 24
| 108
| 2.487187
| 0.012876
|
Q14527,Q5JRX3,Q9BQG2,Q15437,P55786,O75976,Q03164,P09960,P42892,Q8N4Q0,Q15436,P19474,Q9UIQ6,O43813,Q8NCC3,Q8N8N7,P34896,Q99536,Q8IXJ6,Q9NUD5,Q9NWV4,P07814,Q86WB0,Q5JPH6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
267,272,280,279,23,276,157,283,39,45,304,50,58,201,88,93,97,235,109,239,243,244,249,124
|
2152,605,201,430,318,276,2154,1338,1018,1151,1339,2088,446,1194,1758,244,1021,1894,283,1485,873,1447,50,958,985,986,1023,2030,596,1999,97,2062,2242,879,39,990,1161,2266,1204,1308,1837,1537,1764,23,1208,157,1649,1617,526,1500,1282,1421,267,1251,2098,1214,1505,1844,304,279,823,2348,2102,124,272,1809,2048,1545,1106,2104,1107,249,1982,109,45,93,512,88,646,1856,1176,1667,2260,2108,1630,235,1910,280,935,1007,1780,2168,1183,239,243,427,390,1519,903,2054,58,1435,945,1676,552,2150,867,947
|
-0.8543859267849101,0.44490440798943937,1.2290815354843998,0.6709000913867084,0.9022559500015589,1.0020254240102997,-0.8543859267849101,-0.1430695347463049,0.09954637705818221,-0.006127331605984542,-0.1430695347463049,-0.7864806683003362,0.6490043765907978,-0.033074608598505244,-0.46522306940850683,1.0795911798832665,0.09954637705818221,-0.590226648688484,0.9823261264765617,-0.2567482190180186,0.20197116058474252,-0.22797146657486117,2.5658905492788504,0.15115395482942545,0.1254502957539166,0.1254502957539166,0.09954637705818221,-0.7198459356446938,0.4682311897943023,-0.6869921898793442,1.9251128862095315,-0.7530070814189461,-1.0299934512102915,0.20197116058474252,2.827005651000117,0.1254502957539166,-0.006127331605984542,-1.1026963504909864,-0.033074608598505244,-0.11523365842189977,-0.5271658967301447,-0.2857688748733796,-0.46522306940850683,3.0739178449056257,-0.033074608598505244,1.4741558928304515,-0.3743308591385381,-0.34455645734238355,0.5598892765754294,-0.2567482190180186,-0.08762466761145592,-0.1994350717264357,1.0410518943199942,-0.06023936284890438,-0.7864806683003362,-0.033074608598505244,-0.2567482190180186,-0.5271658967301447,0.9425484828699386,1.0020254240102997,0.25201882658425456,-1.3691701581343436,-0.7864806683003362,1.6692773995529553,1.0216002256059087,-0.4960569056469889,-0.7198459356446938,-0.2857688748733796,0.047126781746465576,-0.7864806683003362,0.047126781746465576,1.0795911798832665,-0.65444091817572,1.8224978231489162,2.6558060787814783,1.9821392383520264,0.58240161346863,2.065588110324613,0.42140856532916043,-0.5271658967301447,-0.006127331605984542,-0.3743308591385381,-1.066163090613305,-0.7864806683003362,-0.34455645734238355,1.1365094929601929,-0.590226648688484,1.0020254240102997,0.17666003360338126,0.1254502957539166,-0.46522306940850683,-0.8543859267849101,-0.006127331605984542,1.117653769245169,1.0986814186639104,0.692646228876154,0.7570047251940325,-0.2567482190180186,0.20197116058474252,-0.7198459356446938,2.4728673792906726,-0.1994350717264357,0.17666003360338126,-0.3743308591385381,0.5372180454514659,-0.8202718560579666,0.22708991471684983,0.17666003360338126
| 2,468
|
Transcriptional regulation by runx2
| 16
| 46
| 2.486072
| 0.012916
|
P28070,Q99436,O43242,O00231,P11802,P49841,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,223,327,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,781,223,1057,756,202,1059,1532,1158,1305,1198,1199,225,373,54,634,1872,1382,1240,1093,230,56,327,557,994,408,436,845,1279,884,470,821,695,2269,2215,499,1951,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.27676037958362715,1.1552498319919475,0.07343946733113242,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,0.42140856532916043,-0.5585543448403263,-0.17113556168396907,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.8819129546814536,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,-0.6221873063453945,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
| 14
| 42
| 2.485467
| 0.012938
|
Q16763,P28070,Q99436,O00231,O43242,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
260,225,164,251,533,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1492,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,2215,499,260,164,1177,703,710,1013,774,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.2567482190180186,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.0603817720347808,1.4232989777185565,-0.006127331605984542,0.3739010819588171,0.3739010819588171,0.1254502957539166,0.3013170110599651,1.5406396934742081,-0.06023936284890438
| 2,468
|
Inorganic anion transmembrane transporter activity
| 6
| 15
| 2.483669
| 0.013004
|
P21796,Q9UBX3,P45880,P33527,Q9C0H2,P04920
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
4,199,7,75,89,187
|
1567,1637,187,537,4,75,7,2392,1245,1803,1507,439,89,199,275
|
-0.3150370549937861,-0.3743308591385381,1.2833019254548965,0.5372180454514659,3.838410894509741,2.199400481282764,3.6667004853346468,-1.6138737694884546,-0.06023936284890438,-0.4960569056469889,-0.2567482190180186,0.6709000913867084,2.0518497400362734,1.2472629393969026,1.0216002256059087
| 2,468
|
Interleukin 1 signaling
| 15
| 41
| 2.476025
| 0.013285
|
P09429,P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
319,225,164,533,251,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,319,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,1350,436,845,1279,884,470,1542,821,695,2269,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.9022559500015589,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,-0.1430695347463049,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,-0.2857688748733796,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Selective autophagy
| 7
| 27
| 2.47056
| 0.01349
|
P54619,P21796,Q8N4H5,P04350,P08670,Q9NS69,P68371
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
196,4,198,333,357,29,312
|
1053,1477,837,1019,333,732,357,1445,1303,4,196,993,1699,1350,737,312,1622,618,1213,1283,198,1327,1986,726,458,29,1082
|
0.07343946733113242,-0.2567482190180186,0.22708991471684983,0.09954637705818221,0.8614368152158327,0.3256911134093675,0.7991941651751763,-0.22797146657486117,-0.11523365842189977,3.838410894509741,1.2472629393969026,0.1254502957539166,-0.4043641190777143,-0.1430695347463049,0.3256911134093675,0.9224673008330843,-0.34455645734238355,0.44490440798943937,-0.033074608598505244,-0.08762466761145592,1.2472629393969026,-0.11523365842189977,-0.65444091817572,0.34988503514948976,0.6490043765907978,2.928608323075618,0.07343946733113242
| 2,468
|
Proteasome complex
| 14
| 44
| 2.468596
| 0.013564
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P54727,P61289,P49721,P60900,P28072,P28074
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
225,164,533,251,230,202,499,147,558,436,56,408,373,54
|
251,1266,2221,1226,533,1640,1570,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,1061,558,994,1699,408,436,845,1279,884,1313,821,695,2215,499,927,1457,164,1177,147,1265,1475
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,-0.3150370549937861,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.07343946733113242,0.5143859578494419,0.1254502957539166,-0.4043641190777143,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,-0.11523365842189977,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,0.17666003360338126,-0.22797146657486117,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438,-0.22797146657486117
| 2,468
|
Vascular skin abnormality
| 27
| 90
| 2.465053
| 0.013699
|
Q13126,Q14739,P16278,Q15437,P15924,P22830,Q8IZA0,O75844,P21359,P40763,Q9Y487,Q969U7,P04066,Q06124,P00403,O00170,P07858,P10619,Q8NCH0,Q14108,P06280,P53701,Q06136,P04062,P49257,O75306,Q9BZK7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,139,18,279,404,150,285,36,415,416,181,441,310,451,324,207,80,81,85,84,339,96,98,236,119,371,265
|
207,1189,2366,1727,371,36,2367,324,1609,236,310,339,2028,80,1894,81,448,982,2416,404,18,1155,813,1573,1379,415,957,632,1927,150,2030,1344,634,716,2061,1533,597,666,1160,1534,524,416,119,1094,959,638,2392,2317,96,1537,1764,844,1384,2008,1542,1454,451,98,526,616,0,84,1583,139,2135,1103,2009,279,2258,1657,1981,2103,1141,2407,285,1286,85,896,2230,441,1516,1910,265,703,1399,942,1225,1149,552,181
|
1.2107906833937936,-0.033074608598505244,-1.4489724671135231,-0.4346601796282852,0.7781699552447922,2.868122282262257,-1.4489724671135231,0.8819129546814536,-0.34455645734238355,1.117653769245169,0.9224673008330843,0.8408260074769911,-0.7198459356446938,2.1599235408173723,-0.590226648688484,2.1599235408173723,0.6490043765907978,0.1254502957539166,-1.9209411773807756,0.7142445586094798,3.1754755052007098,-0.006127331605984542,0.25201882658425456,-0.3150370549937861,-0.17113556168396907,0.692646228876154,0.15115395482942545,0.42140856532916043,-0.6221873063453945,1.5075840575864408,-0.7198459356446938,-0.1430695347463049,0.42140856532916043,0.34988503514948976,-0.7530070814189461,-0.2857688748733796,0.4682311897943023,0.3977415176858454,-0.006127331605984542,-0.2857688748733796,0.5598892765754294,0.692646228876154,1.7468979457042964,0.047126781746465576,0.15115395482942545,0.42140856532916043,-1.6138737694884546,-1.2525962685132521,1.9679892965036938,-0.2857688748733796,-0.46522306940850683,0.22708991471684983,-0.17113556168396907,-0.6869921898793442,-0.2857688748733796,-0.22797146657486117,0.6490043765907978,1.9251128862095315,0.5598892765754294,0.44490440798943937,4.207826306124421,2.119881427808456,-0.3150370549937861,1.6056618506283145,-0.8202718560579666,0.047126781746465576,-0.6869921898793442,1.0020254240102997,-1.066163090613305,-0.3743308591385381,-0.65444091817572,-0.7864806683003362,0.020605480698360126,-1.7863055278776567,0.9823261264765617,-0.08762466761145592,2.119881427808456,0.20197116058474252,-0.994181179090294,0.6709000913867084,-0.2567482190180186,-0.590226648688484,1.0603817720347808,0.3739010819588171,-0.17113556168396907,0.17666003360338126,-0.033074608598505244,0.020605480698360126,0.5372180454514659,1.3189165219976549
| 2,468
|
Deubiquitination
| 25
| 72
| 2.463188
| 0.013771
|
Q9Y3E5,P21796,O00231,P45880,Q96FW1,Q9UL46,Q9Y277,P60900,Q86UV5,Q99436,O43242,P54727,P51665,P61289,P49721,P28074,P20618,Q9UPU5,P28070,P49720,Q15008,O14964,P28072,Q93009,Q8NB78
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
391,4,251,7,399,147,275,408,410,164,533,558,557,436,56,54,202,212,225,230,499,487,373,513,512
|
251,1266,2221,1226,487,684,533,1638,1640,1477,1795,1758,781,873,756,202,4,1059,1532,1158,1305,1199,225,373,54,1872,1240,7,1161,1093,230,56,2126,557,1061,558,994,1699,408,436,1385,845,1279,884,821,695,583,1503,1167,2215,499,1283,410,1588,2456,512,896,828,513,399,164,1177,1630,1186,147,1265,212,2148,275,391,2278,1475
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.6047569844332618,0.3739010819588171,0.5372180454514659,-0.3743308591385381,-0.3743308591385381,-0.2567482190180186,-0.4960569056469889,-0.46522306940850683,0.27676037958362715,0.20197116058474252,0.3013170110599651,1.2290815354843998,3.838410894509741,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,3.6667004853346468,-0.006127331605984542,0.047126781746465576,1.1365094929601929,2.4964247239663777,-0.8202718560579666,0.5143859578494419,0.07343946733113242,0.5143859578494419,0.1254502957539166,-0.4043641190777143,0.7142445586094798,0.6709000913867084,-0.17113556168396907,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,0.49139101679695213,-0.2567482190180186,-0.006127331605984542,-0.958720173237647,0.6047569844332618,-0.08762466761145592,0.7142445586094798,-0.3150370549937861,-3.3908979163224866,0.58240161346863,0.20197116058474252,0.25201882658425456,0.58240161346863,0.7356968204452725,1.4232989777185565,-0.006127331605984542,-0.34455645734238355,-0.006127331605984542,1.5406396934742081,-0.06023936284890438,1.2107906833937936,-0.8202718560579666,1.0216002256059087,0.7570047251940325,-1.1026963504909864,-0.22797146657486117
| 2,468
|
Lipoprotein metabolic process
| 6
| 14
| 2.462286
| 0.013805
|
Q9NUJ1,Q15042,Q5H8A4,P50897,Q9BQE5,Q16739
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
72,233,142,112,20,92
|
1267,236,1381,112,233,92,142,895,2230,2410,20,727,1598,72
|
-0.08762466761145592,1.117653769245169,-0.17113556168396907,1.807535106013106,1.1365094929601929,2.024171009993822,1.5895402794086952,0.20197116058474252,-0.994181179090294,-1.7863055278776567,3.139012561494263,0.34988503514948976,-0.3150370549937861,2.2511809259257114
| 2,468
|
Apc c mediated degradation of cell cycle proteins
| 16
| 49
| 2.45181
| 0.014214
|
Q16763,P24941,P28070,Q99436,O00231,O43242,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
260,224,225,164,251,533,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,779,752,1640,781,1057,756,202,224,1059,1532,1158,1305,1199,225,373,54,1492,1872,1240,1093,230,56,557,994,408,436,845,1279,884,470,821,695,2269,2215,499,260,164,1177,703,710,1013,774,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,0.27676037958362715,0.3013170110599651,-0.3743308591385381,0.27676037958362715,0.07343946733113242,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.2567482190180186,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,1.0603817720347808,1.4232989777185565,-0.006127331605984542,0.3739010819588171,0.3739010819588171,0.1254502957539166,0.3013170110599651,1.5406396934742081,-0.06023936284890438
| 2,468
|
Transport to the golgi and subsequent modification
| 31
| 64
| 2.439265
| 0.014717
|
P24390,P35606,Q9Y678,Q15436,Q15363,P68371,P04066,O14653,Q9BVA1,Q13561,P49755,Q14789,Q13813,P04350,Q9BUF5,Q9HCU5,Q12893,Q9UJW0,Q92538,Q08379,Q13885,Q9BVK6,P63167,Q9Y3B3,Q9Y3Q3,Q14203,Q99747,O75935,P62820,P49257,P61923
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
5,291,295,304,698,312,310,683,458,328,692,584,582,333,726,481,350,355,476,471,618,747,737,367,368,498,501,108,359,119,764
|
1336,750,683,870,1407,1681,1476,2086,108,1523,310,333,1528,5,291,2123,1203,817,881,119,692,1243,1126,843,1537,1971,1063,764,359,737,312,1030,471,350,1741,1650,923,1622,328,582,618,498,1213,584,698,304,1847,1110,1460,476,1950,1327,1551,501,726,458,747,1597,481,355,367,368,295,1082
|
-0.1430695347463049,0.3013170110599651,0.3739010819588171,0.20197116058474252,-0.1994350717264357,-0.4043641190777143,-0.2567482190180186,-0.7864806683003362,1.8373833245061917,-0.2857688748733796,0.9224673008330843,0.8614368152158327,-0.2857688748733796,3.8314985860427604,0.9625009483378237,-0.8202718560579666,-0.033074608598505244,0.25201882658425456,0.20197116058474252,1.7468979457042964,0.3739010819588171,-0.06023936284890438,0.020605480698360126,0.22708991471684983,-0.2857688748733796,-0.65444091817572,0.07343946733113242,0.3013170110599651,0.7991941651751763,0.3256911134093675,0.9224673008330843,0.09954637705818221,0.6269572845849924,0.8200789823454424,-0.4346601796282852,-0.3743308591385381,0.17666003360338126,-0.34455645734238355,0.8819129546814536,0.49139101679695213,0.44490440798943937,0.6047569844332618,-0.033074608598505244,0.49139101679695213,0.3739010819588171,0.9425484828699386,-0.5271658967301447,0.047126781746465576,-0.22797146657486117,0.6269572845849924,-0.6221873063453945,-0.11523365842189977,-0.2857688748733796,0.6047569844332618,0.34988503514948976,0.6490043765907978,0.3256911134093675,-0.3150370549937861,0.6269572845849924,0.8200789823454424,0.7991941651751763,0.7991941651751763,0.9625009483378237,0.07343946733113242
| 2,468
|
Azurophil granule
| 13
| 56
| 2.439117
| 0.014723
|
O00584,P42785,P15586,Q99536,P07437,P16278,P10619,P06865,Q9BTY2,P06280,P68371,P04066,P07602
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
281,8,325,235,299,18,81,209,152,339,312,310,31
|
2113,281,729,2083,1637,953,1120,1683,310,339,209,1829,299,31,536,1234,81,1302,1484,325,18,609,2059,634,1694,1697,8,1579,819,1205,1836,669,1027,1244,1699,735,312,497,1248,349,1806,1213,2203,1628,1663,1665,827,1430,1177,235,1910,152,863,628,1916,531
|
-0.8202718560579666,0.9823261264765617,0.3256911134093675,-0.7864806683003362,-0.3743308591385381,0.15115395482942545,0.020605480698360126,-0.4043641190777143,0.9224673008330843,0.8408260074769911,1.2107906833937936,-0.5271658967301447,0.9425484828699386,2.908601987092757,0.5372180454514659,-0.06023936284890438,2.1599235408173723,-0.11523365842189977,-0.2567482190180186,0.8819129546814536,3.1754755052007098,0.44490440798943937,-0.7530070814189461,0.42140856532916043,-0.4043641190777143,-0.4043641190777143,3.5056872507526013,-0.3150370549937861,0.25201882658425456,-0.033074608598505244,-0.5271658967301447,0.3977415176858454,0.09954637705818221,-0.06023936284890438,-0.4043641190777143,0.3256911134093675,0.9224673008330843,0.6047569844332618,-0.06023936284890438,0.8200789823454424,-0.4960569056469889,-0.033074608598505244,-0.9236044800386676,-0.34455645734238355,-0.3743308591385381,-0.3743308591385381,0.25201882658425456,-0.1994350717264357,-0.006127331605984542,1.1365094929601929,-0.590226648688484,1.5075840575864408,0.22708991471684983,0.44490440798943937,-0.590226648688484,0.5598892765754294
| 2,468
|
Glycosaminoglycan metabolism
| 6
| 10
| 2.434797
| 0.0149
|
Q8TB61,Q7LGA3,P15586,P06865,P16278,Q8NCH0
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,204,325,209,18,85
|
344,209,536,325,18,693,204,85,128,903
|
0.8200789823454424,1.2107906833937936,0.5372180454514659,0.8819129546814536,3.1754755052007098,0.3739010819588171,1.2290815354843998,2.119881427808456,1.6535024833174539,0.20197116058474252
| 2,468
|
Hedgehog ligand biogenesis
| 13
| 39
| 2.432895
| 0.014979
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,1086,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,1699,408,436,845,1279,884,821,695,2215,499,164,1177,681,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.047126781746465576,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,-0.4043641190777143,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,0.3977415176858454,1.5406396934742081,-0.06023936284890438
| 2,468
|
Golgi associated vesicle
| 7
| 27
| 2.428432
| 0.015164
|
P35606,P24390,Q8N511,Q9Y678,Q9Y3Q3,O43493,P11717
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
291,5,6,295,368,266,221
|
750,266,1793,2156,1831,221,5,291,881,692,960,1126,843,1737,1701,764,847,1209,698,6,1460,747,1042,1469,367,368,295
|
0.3013170110599651,1.0410518943199942,-0.4960569056469889,-0.8543859267849101,-0.5271658967301447,1.1738760097490326,3.8314985860427604,0.9625009483378237,0.20197116058474252,0.3739010819588171,0.15115395482942545,0.020605480698360126,0.22708991471684983,-0.4346601796282852,-0.4043641190777143,0.3013170110599651,0.22708991471684983,-0.033074608598505244,0.3739010819588171,3.681490447648572,-0.22797146657486117,0.3256911134093675,0.09954637705818221,-0.22797146657486117,0.7991941651751763,0.7991941651751763,0.9625009483378237
| 2,468
|
Protease
| 29
| 90
| 2.426017
| 0.015266
|
Q10713,P42785,Q96FW1,P52888,O14773,Q5JRX3,P55786,Q9NZ08,O75844,P42892,P49915,P67812,Q8IYS1,Q8TCT9,Q9UIQ6,P22695,Q96AE4,Q9HB40,Q4KMP7,Q9H3G5,P07858,P10619,O43847,Q8TC07,Q13510,Q5BJF2,P17812,Q9BYT8,Q92905
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
257,8,399,12,141,272,23,427,36,39,417,173,440,314,58,59,322,68,329,74,80,81,345,363,361,116,120,250,263
|
682,1015,2221,141,572,345,714,1606,36,432,1644,80,912,81,1273,2416,1235,873,120,2356,59,1023,2334,2031,663,1696,2035,539,8,39,1161,1899,417,557,12,1616,1538,1061,23,1499,599,173,1031,849,257,1130,361,794,1167,699,1656,1318,329,2102,116,272,1706,930,1356,440,2204,2205,363,314,895,827,263,2106,477,513,322,399,1113,1746,1986,2343,2467,250,1396,74,1748,68,427,1369,568,58,775,2150,1475,595
|
0.3739010819588171,0.09954637705818221,-0.994181179090294,1.5895402794086952,0.49139101679695213,0.8200789823454424,0.34988503514948976,-0.34455645734238355,2.868122282262257,0.6709000913867084,-0.3743308591385381,2.1599235408173723,0.17666003360338126,2.1599235408173723,-0.08762466761145592,-1.9209411773807756,-0.06023936284890438,0.20197116058474252,1.716097436457639,-1.4088574939002534,2.461011602486414,0.09954637705818221,-1.3299025873109733,-0.7198459356446938,0.3977415176858454,-0.4043641190777143,-0.7198459356446938,0.5372180454514659,3.5056872507526013,2.827005651000117,-0.006127331605984542,-0.590226648688484,0.692646228876154,0.5143859578494419,3.4332901983397086,-0.34455645734238355,-0.2857688748733796,0.07343946733113242,3.0739178449056257,-0.2567482190180186,0.4682311897943023,1.3365673787376733,0.09954637705818221,0.22708991471684983,1.0603817720347808,0.020605480698360126,0.7991941651751763,0.27676037958362715,-0.006127331605984542,0.3739010819588171,-0.3743308591385381,-0.11523365842189977,0.8819129546814536,-0.7864806683003362,1.7924944732535362,1.0216002256059087,-0.4043641190777143,0.17666003360338126,-0.1430695347463049,0.6709000913867084,-0.9236044800386676,-0.9236044800386676,0.7991941651751763,0.9224673008330843,0.20197116058474252,0.25201882658425456,1.0603817720347808,-0.7864806683003362,0.6269572845849924,0.58240161346863,0.9022559500015589,0.7356968204452725,0.047126781746465576,-0.4346601796282852,-0.65444091817572,-1.3299025873109733,-10.399284047667013,1.0795911798832665,-0.17113556168396907,2.2254112620780373,-0.4346601796282852,2.3270814179529142,0.692646228876154,-0.1430695347463049,0.5143859578494419,2.4728673792906726,0.3013170110599651,-0.8202718560579666,-0.22797146657486117,0.49139101679695213
| 2,468
|
Abnormal heart valve morphology
| 17
| 59
| 2.423398
| 0.015376
|
P55795,P21359,P37268,O75844,Q06124,Q6PGP7,Q9NVI1,P10644,Q5H8A4,P04062,Q9UHX1,P16278,Q8NCH0,P06280,Q9Y4P3,P53701,O75431
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
226,415,131,36,451,203,402,448,142,236,240,18,85,339,190,96,191
|
1335,1189,684,952,2195,191,36,1300,535,1609,236,339,447,1894,448,18,1379,415,632,1927,634,716,576,784,131,1092,1276,2392,2317,96,1537,844,226,1351,599,1937,1311,1030,1542,1454,451,1767,925,1137,1067,1317,142,1284,2103,203,1510,85,896,1516,402,240,2054,1225,190
|
-0.1430695347463049,-0.033074608598505244,0.3739010819588171,0.15115395482942545,-0.9236044800386676,1.2653360299982175,2.868122282262257,-0.11523365842189977,0.5372180454514659,-0.34455645734238355,1.117653769245169,0.8408260074769911,0.6490043765907978,-0.590226648688484,0.6490043765907978,3.1754755052007098,-0.17113556168396907,0.692646228876154,0.42140856532916043,-0.6221873063453945,0.42140856532916043,0.34988503514948976,0.49139101679695213,0.27676037958362715,1.6376421273678423,0.047126781746465576,-0.08762466761145592,-1.6138737694884546,-1.2525962685132521,1.9679892965036938,-0.2857688748733796,0.22708991471684983,1.1552498319919475,-0.1430695347463049,0.4682311897943023,-0.6221873063453945,-0.11523365842189977,0.09954637705818221,-0.2857688748733796,-0.22797146657486117,0.6490043765907978,-0.46522306940850683,0.17666003360338126,0.020605480698360126,0.07343946733113242,-0.11523365842189977,1.5895402794086952,-0.08762466761145592,-0.7864806683003362,1.2290815354843998,-0.2567482190180186,2.119881427808456,0.20197116058474252,-0.2567482190180186,0.7356968204452725,1.117653769245169,-0.7198459356446938,-0.033074608598505244,1.2833019254548965
| 2,468
|
Cellular response to biotic stimulus
| 10
| 29
| 2.412256
| 0.015854
|
P09429,O75844,Q8WTV0,P11802,P49841,P30536,Q8IXJ6,P08670,Q9Y263,P14174
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
319,36,38,223,327,73,109,357,145,277
|
36,1758,357,319,223,277,395,1198,634,73,1762,327,1385,1583,1944,1547,891,2361,1071,109,2140,38,1856,897,2049,1078,1367,1563,145
|
2.868122282262257,-0.46522306940850683,0.7991941651751763,0.9022559500015589,1.1552498319919475,1.0020254240102997,0.7356968204452725,-0.033074608598505244,0.42140856532916043,2.238325990048142,-0.46522306940850683,0.8819129546814536,-0.17113556168396907,-0.3150370549937861,-0.6221873063453945,-0.2857688748733796,0.20197116058474252,-1.4088574939002534,0.07343946733113242,1.8224978231489162,-0.8202718560579666,2.857903513986415,-0.5271658967301447,0.20197116058474252,-0.7198459356446938,0.07343946733113242,-0.1430695347463049,-0.2857688748733796,1.5570300603921419
| 2,468
|
Inflammatory response
| 15
| 48
| 2.407592
| 0.016058
|
P09429,Q9UNH7,P28070,Q8IV08,P42785,P40763,P33527,P04062,P26583,Q9Y263,Q9BQE5,P14174,P60900,P02786,Q96BN8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
319,428,225,100,8,416,75,236,395,145,20,277,408,432,388
|
2113,835,753,1192,446,432,236,1757,1963,319,522,277,1688,1059,395,225,733,1762,75,2000,416,1614,8,1094,669,408,1937,1906,1130,1651,853,2259,1507,1879,100,965,388,898,932,1713,1630,1986,1115,20,1364,1369,428,145
|
-0.8202718560579666,0.22708991471684983,0.3013170110599651,-0.033074608598505244,0.6490043765907978,0.6709000913867084,1.117653769245169,-0.46522306940850683,-0.65444091817572,0.9022559500015589,0.5598892765754294,1.0020254240102997,-0.4043641190777143,0.07343946733113242,0.7356968204452725,1.1552498319919475,0.3256911134093675,-0.46522306940850683,2.199400481282764,-0.6869921898793442,0.692646228876154,-0.34455645734238355,3.5056872507526013,0.047126781746465576,0.3977415176858454,0.7142445586094798,-0.6221873063453945,-0.590226648688484,0.020605480698360126,-0.3743308591385381,0.22708991471684983,-1.066163090613305,-0.2567482190180186,-0.5585543448403263,1.9106764725104468,0.15115395482942545,0.7570047251940325,0.20197116058474252,0.17666003360338126,-0.4043641190777143,-0.34455645734238355,-0.65444091817572,0.047126781746465576,3.139012561494263,-0.1430695347463049,-0.1430695347463049,0.692646228876154,1.5570300603921419
| 2,468
|
Degradation of gli1 by the proteasome
| 14
| 40
| 2.403633
| 0.016233
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,1155,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,470,821,695,2269,2215,499,898,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,-0.006127331605984542,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,0.20197116058474252,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Nucleoside triphosphatase regulator activity
| 20
| 58
| 2.402109
| 0.016301
|
Q02818,P55010,Q15437,P21359,O00429,Q15436,P49770,P80303,Q4KMP7,Q9Y4G8,Q9HCU5,Q9P035,Q92538,Q8TC07,Q14C86,Q15042,Q13144,Q14344,Q9P2J5,Q14185
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
137,16,279,415,412,304,302,64,329,484,481,482,476,363,232,233,360,376,516,258
|
520,412,714,1794,1193,1528,1998,415,915,1024,1493,880,1200,1162,302,1383,1579,1615,16,737,64,1209,137,1132,360,1582,258,1652,376,232,233,797,304,279,329,1769,2203,2139,1110,363,476,1176,2386,802,831,1365,727,1292,970,481,1146,482,629,516,1471,594,775,484
|
0.5598892765754294,0.692646228876154,0.34988503514948976,-0.4960569056469889,-0.033074608598505244,-0.2857688748733796,-0.6869921898793442,0.692646228876154,0.17666003360338126,0.09954637705818221,-0.2567482190180186,0.20197116058474252,-0.033074608598505244,-0.006127331605984542,0.9425484828699386,-0.17113556168396907,-0.3150370549937861,-0.34455645734238355,3.2380483858021836,0.3256911134093675,2.3642621621233513,-0.033074608598505244,1.6056618506283145,0.020605480698360126,0.7991941651751763,-0.3150370549937861,1.0603817720347808,-0.3743308591385381,0.7781699552447922,1.1365094929601929,1.1365094929601929,0.27676037958362715,0.9425484828699386,1.0020254240102997,0.8819129546814536,-0.46522306940850683,-0.9236044800386676,-0.8202718560579666,0.047126781746465576,0.7991941651751763,0.6269572845849924,-0.006127331605984542,-1.5719651640648913,0.27676037958362715,0.25201882658425456,-0.1430695347463049,0.34988503514948976,-0.08762466761145592,0.15115395482942545,0.6269572845849924,0.020605480698360126,0.6269572845849924,0.44490440798943937,0.58240161346863,-0.22797146657486117,0.49139101679695213,0.3013170110599651,0.6269572845849924
| 2,468
|
Transporters
| 69
| 311
| 2.393455
| 0.016691
|
Q8TB61,Q15629,Q70HW3,Q8TEX9,P24390,Q8N511,P45880,Q8IXU6,Q9H2D1,Q6NT16,Q9BTX1,P40855,P23634,P54105,O96005,Q9HBM0,Q8N4V1,Q15904,Q8N1F7,P07602,P08183,O75844,Q8WTV0,O43772,Q92973,P53985,P55061,P63241,Q9HC07,O00429,Q9NPI6,Q9HD20,Q99805,Q8NFH4,Q99720,O15397,P39210,Q6N075,P16615,P02786,O75436,P04920,P09132,Q9UBU6,Q9H061,Q9UBX3,Q93050,P33527,P00403,O15258,Q8IYI6,Q14108,Q99808,Q9BPX6,P35613,Q9C0H2,Q16739,P11717,Q07065,Q9Y3Q3,Q9Y3B3,P62942,Q92544,O60637,Q5BJF2,P49257,Q9BZF1,O94901,Q9Y619
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
128,259,3,387,5,6,7,13,14,15,144,396,394,151,154,287,286,284,423,31,32,36,38,37,293,40,419,171,307,412,444,47,180,179,443,296,176,439,434,432,431,187,192,65,70,199,76,75,324,208,211,84,342,217,214,89,92,221,349,368,367,238,242,111,116,119,264,372,125
|
1791,2113,1567,520,2355,412,1825,1335,655,751,836,977,488,978,208,296,1637,1793,1726,37,534,505,553,714,1638,111,753,2024,2195,1054,1728,2402,1828,907,431,1961,1374,1411,1412,36,2056,1756,573,372,1682,1523,837,1300,2239,1193,909,1121,2156,154,1019,324,2373,432,1924,1757,1479,1758,1231,1195,187,981,1642,2157,1963,781,1829,31,1965,32,1481,956,192,1831,1572,491,2294,1484,221,811,1612,574,1154,1057,1687,434,2170,1690,2255,914,2171,1379,957,394,5,2059,1490,1897,815,75,214,1695,666,1930,612,524,1931,176,1697,396,7,1200,2123,734,119,762,692,2347,1383,1497,1205,1934,1735,2392,509,918,1616,2066,1278,40,151,993,2283,1245,670,419,1699,671,1451,2068,2318,1206,995,1702,2399,2128,961,238,1740,1029,171,1453,579,1841,1098,2008,2070,847,1803,998,674,349,675,1618,1314,1102,1281,1874,923,1742,84,1766,742,1214,2136,560,698,259,1544,284,585,890,92,643,1507,116,2319,1847,1508,2178,439,15,2103,1141,1945,1000,1510,3,1848,13,1772,211,423,286,6,1882,965,2285,179,1038,2310,1001,128,475,1393,1219,1854,387,38,967,2144,242,1175,896,293,76,1142,897,1257,2299,1857,624,1463,1289,647,1221,1551,1713,969,746,443,180,342,217,1715,2015,144,1717,1718,1747,2016,1004,264,89,70,863,14,1366,1396,2413,1886,1397,1433,1633,650,287,307,834,481,47,1042,1887,444,1722,1009,628,1916,1600,65,2208,681,199,2292,1116,1560,806,462,1117,1400,1370,1297,2209,1753,1563,749,502,518,1298,1403,367,368,1679,1372,2253,904,125,1437
|
-0.4960569056469889,-0.8202718560579666,-0.3150370549937861,0.5598892765754294,-1.4088574939002534,0.692646228876154,-0.5271658967301447,-0.1430695347463049,0.3977415176858454,0.3013170110599651,0.22708991471684983,0.1254502957539166,0.6047569844332618,0.1254502957539166,1.2107906833937936,0.9425484828699386,-0.3743308591385381,-0.4960569056469889,-0.4346601796282852,2.857903513986415,0.5372180454514659,0.58240161346863,0.5143859578494419,0.34988503514948976,-0.3743308591385381,1.807535106013106,0.3013170110599651,-0.7198459356446938,-0.9236044800386676,0.07343946733113242,-0.4346601796282852,-1.742458928246437,-0.5271658967301447,0.17666003360338126,0.6709000913867084,-0.65444091817572,-0.17113556168396907,-0.1994350717264357,-0.1994350717264357,2.868122282262257,-0.7530070814189461,-0.46522306940850683,0.49139101679695213,0.7781699552447922,-0.4043641190777143,-0.2857688748733796,0.22708991471684983,-0.11523365842189977,-1.0299934512102915,-0.033074608598505244,0.17666003360338126,0.020605480698360126,-0.8543859267849101,1.4909169970454357,0.09954637705818221,0.8819129546814536,-1.4895231624354457,0.6709000913867084,-0.6221873063453945,-0.46522306940850683,-0.2567482190180186,-0.46522306940850683,-0.06023936284890438,-0.033074608598505244,1.2833019254548965,0.1254502957539166,-0.3743308591385381,-0.8543859267849101,-0.65444091817572,0.27676037958362715,-0.5271658967301447,2.908601987092757,-0.65444091817572,2.908601987092757,-0.2567482190180186,0.15115395482942545,1.2653360299982175,-0.5271658967301447,-0.3150370549937861,0.6047569844332618,-1.1768795353111265,-0.2567482190180186,1.1738760097490326,0.25201882658425456,-0.34455645734238355,0.49139101679695213,-0.006127331605984542,0.07343946733113242,-0.4043641190777143,0.6709000913867084,-0.8888282886905626,-0.4043641190777143,-1.066163090613305,0.17666003360338126,-0.8888282886905626,-0.17113556168396907,0.15115395482942545,0.7356968204452725,3.8314985860427604,-0.7530070814189461,-0.2567482190180186,-0.590226648688484,0.25201882658425456,2.199400481282764,1.192389231232484,-0.4043641190777143,0.3977415176858454,-0.6221873063453945,0.44490440798943937,0.5598892765754294,-0.6221873063453945,1.3189165219976549,-0.4043641190777143,0.7356968204452725,3.6667004853346468,-0.033074608598505244,-0.8202718560579666,0.3256911134093675,1.7468979457042964,0.3013170110599651,0.3739010819588171,-1.3691701581343436,-0.17113556168396907,-0.2567482190180186,-0.033074608598505244,-0.6221873063453945,-0.4346601796282852,-1.6138737694884546,0.58240161346863,0.17666003360338126,-0.34455645734238355,-0.7530070814189461,-0.08762466761145592,2.827005651000117,1.5075840575864408,0.1254502957539166,-1.139599641176551,-0.06023936284890438,0.3977415176858454,0.692646228876154,-0.4043641190777143,0.3977415176858454,-0.22797146657486117,-0.7530070814189461,-1.2525962685132521,-0.033074608598505244,0.1254502957539166,-0.4043641190777143,-1.6562527119273847,-0.8202718560579666,0.15115395482942545,1.117653769245169,-0.4346601796282852,0.09954637705818221,1.3541153522401639,-0.22797146657486117,0.49139101679695213,-0.5271658967301447,0.047126781746465576,-0.6869921898793442,-0.7530070814189461,0.22708991471684983,-0.4960569056469889,0.1254502957539166,0.3977415176858454,0.8200789823454424,0.3977415176858454,-0.34455645734238355,-0.11523365842189977,0.047126781746465576,-0.08762466761145592,-0.5585543448403263,0.17666003360338126,-0.4346601796282852,2.119881427808456,-0.46522306940850683,0.3256911134093675,-0.033074608598505244,-0.8202718560579666,0.5143859578494419,0.3739010819588171,1.0603817720347808,-0.2857688748733796,0.9823261264765617,0.49139101679695213,0.20197116058474252,2.024171009993822,0.42140856532916043,-0.2567482190180186,1.7924944732535362,-1.2525962685132521,-0.5271658967301447,-0.2567482190180186,-0.8888282886905626,0.6709000913867084,3.3248211178078995,-0.7864806683003362,0.020605480698360126,-0.6221873063453945,0.1254502957539166,-0.2567482190180186,4.09320199924866,-0.5271658967301447,3.383816314422708,-0.46522306940850683,1.2107906833937936,0.692646228876154,0.9823261264765617,3.681490447648572,-0.5585543448403263,0.15115395482942545,-1.139599641176551,1.3189165219976549,0.09954637705818221,-1.214542773220608,0.1254502957539166,1.6535024833174539,0.6269572845849924,-0.17113556168396907,-0.033074608598505244,-0.5271658967301447,0.7570047251940325,2.857903513986415,0.15115395482942545,-0.8202718560579666,1.0986814186639104,-0.006127331605984542,0.20197116058474252,0.9625009483378237,2.199400481282764,0.020605480698360126,0.20197116058474252,-0.06023936284890438,-1.1768795353111265,-0.5271658967301447,0.44490440798943937,-0.22797146657486117,-0.08762466761145592,0.42140856532916043,-0.033074608598505244,-0.2857688748733796,-0.4043641190777143,0.15115395482942545,0.3256911134093675,0.6709000913867084,1.3189165219976549,0.8408260074769911,1.192389231232484,-0.4043641190777143,-0.6869921898793442,1.5570300603921419,-0.4043641190777143,-0.4043641190777143,-0.4346601796282852,-0.6869921898793442,0.1254502957539166,1.0603817720347808,2.0518497400362734,2.2893917554224728,0.22708991471684983,3.3671029220870046,-0.1430695347463049,-0.17113556168396907,-1.83066113592861,-0.5585543448403263,-0.17113556168396907,-0.1994350717264357,-0.34455645734238355,0.42140856532916043,0.9823261264765617,0.9425484828699386,0.25201882658425456,0.6269572845849924,2.6224404188956902,0.09954637705818221,-0.5585543448403263,0.6709000913867084,-0.4043641190777143,0.1254502957539166,0.44490440798943937,-0.590226648688484,-0.3150370549937861,2.351924388044598,-0.9236044800386676,0.3977415176858454,1.2472629393969026,-1.139599641176551,0.047126781746465576,-0.2857688748733796,0.27676037958362715,0.6490043765907978,0.047126781746465576,-0.17113556168396907,-0.1430695347463049,-0.08762466761145592,-0.9236044800386676,-0.4346601796282852,-0.2857688748733796,0.3256911134093675,0.6047569844332618,0.58240161346863,-0.08762466761145592,-0.17113556168396907,0.7991941651751763,0.7991941651751763,-0.3743308591385381,-0.1430695347463049,-1.0299934512102915,0.20197116058474252,1.6692773995529553,-0.1994350717264357
| 2,468
|
Regulation of plk1 activity at g2 m transition
| 13
| 30
| 2.392256
| 0.016745
|
Q13561,Q15154,Q14203,P30153,O75935,P04350,P07437,P43034,P68371,Q9H6D7,Q15691,O95684,P63208
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
328,165,498,326,108,333,299,556,312,118,313,60,470
|
108,60,333,781,299,732,1057,1155,326,760,556,1737,1063,600,1936,996,737,470,312,1622,328,2269,1211,498,1213,165,313,1180,118,1670
|
1.8373833245061917,2.43714387569957,0.8614368152158327,0.27676037958362715,0.9425484828699386,0.3256911134093675,0.07343946733113242,-0.006127331605984542,0.8819129546814536,0.3013170110599651,0.5143859578494419,-0.4346601796282852,0.07343946733113242,0.4682311897943023,-0.6221873063453945,0.1254502957539166,0.3256911134093675,0.6269572845849924,0.9224673008330843,-0.34455645734238355,0.8819129546814536,-1.1026963504909864,-0.033074608598505244,0.6047569844332618,-0.033074608598505244,1.4061522919477702,0.9224673008330843,-0.006127331605984542,1.7621766159448307,-0.3743308591385381
| 2,468
|
Metapathway biotransformation phase i and ii
| 6
| 18
| 2.39081
| 0.016811
|
P21266,P07099,Q7LGA3,Q16850,Q86UY6,Q8NCH0
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
254,104,204,43,178,85
|
808,1020,104,1895,1832,254,632,667,271,43,204,178,85,1115,803,1913,1366,2149
|
0.25201882658425456,0.09954637705818221,1.8815833993429565,-0.590226648688484,-0.5271658967301447,1.0603817720347808,0.42140856532916043,0.3977415176858454,1.0216002256059087,2.7427903084146905,1.2290815354843998,1.3189165219976549,2.119881427808456,0.047126781746465576,0.27676037958362715,-0.590226648688484,-0.1430695347463049,-0.8202718560579666
| 2,468
|
Hedgehog on state
| 13
| 40
| 2.383796
| 0.017135
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,1124,230,56,557,994,408,436,845,1279,884,821,695,793,2215,499,1944,898,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,0.020605480698360126,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,0.27676037958362715,-0.958720173237647,0.6047569844332618,-0.6221873063453945,0.20197116058474252,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Biological oxidations
| 9
| 34
| 2.382985
| 0.017173
|
Q8TB61,P21266,Q9NUJ1,P07099,Q16850,O00170,P16435,O43169,P30837
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,254,72,104,43,207,245,24,55
|
207,808,24,810,2196,1683,871,104,956,838,1485,1895,245,254,632,2356,1488,55,716,2411,667,271,542,43,1068,2338,128,589,1115,1366,1293,72,1186,2149
|
1.2107906833937936,0.25201882658425456,3.0644817206400434,0.25201882658425456,-0.9236044800386676,-0.4043641190777143,0.20197116058474252,1.8815833993429565,0.15115395482942545,0.22708991471684983,-0.2567482190180186,-0.590226648688484,1.0795911798832665,1.0603817720347808,0.42140856532916043,-1.4088574939002534,-0.2567482190180186,2.4964247239663777,0.34988503514948976,-1.83066113592861,0.3977415176858454,1.0216002256059087,0.5372180454514659,2.7427903084146905,0.07343946733113242,-1.3299025873109733,1.6535024833174539,0.49139101679695213,0.047126781746465576,-0.1430695347463049,-0.08762466761145592,2.2511809259257114,-0.006127331605984542,-0.8202718560579666
| 2,468
|
Neddylation
| 19
| 64
| 2.368792
| 0.017846
|
O00231,Q9UL46,P60900,P61201,Q99436,Q8N668,O43242,P61289,P49721,P28074,P20618,Q9Y5A7,P63208,P28070,P49720,Q9BT78,Q15008,P28072,Q92905
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
251,147,408,163,164,292,533,436,56,54,202,343,470,225,230,105,499,373,263
|
251,1266,2221,1226,533,2195,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,1540,163,436,1207,2005,845,1279,884,470,821,1132,695,767,2269,1249,793,1387,2215,499,2075,1034,1909,1389,930,1172,292,1287,263,1256,164,1177,1114,105,1363,1783,147,1265,944,343
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.9236044800386676,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,-0.2857688748733796,1.4403478303991744,0.6709000913867084,-0.033074608598505244,-0.6869921898793442,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.020605480698360126,0.3739010819588171,0.3013170110599651,-1.1026963504909864,-0.06023936284890438,0.27676037958362715,-0.17113556168396907,-0.958720173237647,0.6047569844332618,-0.7530070814189461,0.09954637705818221,-0.590226648688484,-0.17113556168396907,0.17666003360338126,-0.006127331605984542,0.9625009483378237,-0.08762466761145592,1.0603817720347808,-0.06023936284890438,1.4232989777185565,-0.006127331605984542,0.047126781746465576,1.8669254347810549,-0.1430695347463049,-0.46522306940850683,1.5406396934742081,-0.06023936284890438,0.17666003360338126,0.8408260074769911
| 2,468
|
Dectin 1 mediated noncanonical nf kb signaling
| 14
| 40
| 2.356953
| 0.018426
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,1540,436,845,1279,884,470,821,695,2269,2215,499,1287,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,-0.2857688748733796,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,-0.08762466761145592,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Tnfr2 non canonical nf kb pathway
| 14
| 40
| 2.356953
| 0.018426
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,1540,436,845,1279,884,470,821,695,2269,2215,499,1287,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,-0.2857688748733796,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,-0.08762466761145592,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Circulatory system process
| 20
| 59
| 2.350851
| 0.018731
|
P42785,P78417,P23634,P15924,P08183,Q9NZ08,O75844,P42892,P53985,O00429,P16615,Q9UIQ6,P02786,Q9HB40,P33527,P00813,Q99808,P11166,Q14344,Q9Y289
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
8,271,394,404,32,427,36,39,40,412,434,58,432,68,75,446,342,491,376,518
|
412,1374,1412,36,1337,1794,2026,1683,446,432,1152,981,1642,32,522,608,1234,491,1485,1196,404,434,1155,1690,1379,394,1966,75,1382,1614,8,39,2411,2124,2065,40,1245,2004,1385,996,579,271,1905,675,2335,617,1033,376,1103,1544,1141,2450,1461,342,1366,68,427,58,518
|
0.692646228876154,-0.17113556168396907,-0.1994350717264357,2.868122282262257,-0.1430695347463049,-0.4960569056469889,-0.7198459356446938,-0.4043641190777143,0.6490043765907978,0.6709000913867084,-0.006127331605984542,0.1254502957539166,-0.3743308591385381,2.908601987092757,0.5598892765754294,0.44490440798943937,-0.06023936284890438,0.6047569844332618,-0.2567482190180186,-0.033074608598505244,0.7142445586094798,0.6709000913867084,-0.006127331605984542,-0.4043641190777143,-0.17113556168396907,0.7356968204452725,-0.65444091817572,2.199400481282764,-0.17113556168396907,-0.34455645734238355,3.5056872507526013,2.827005651000117,-1.83066113592861,-0.8202718560579666,-0.7530070814189461,2.827005651000117,-0.06023936284890438,-0.6869921898793442,-0.17113556168396907,0.1254502957539166,0.49139101679695213,1.0216002256059087,-0.590226648688484,0.3977415176858454,-1.3299025873109733,0.44490440798943937,0.09954637705818221,0.7781699552447922,0.047126781746465576,-0.2857688748733796,0.020605480698360126,-3.078970856737308,-0.22797146657486117,0.8408260074769911,-0.1430695347463049,2.3270814179529142,0.692646228876154,2.4728673792906726,0.58240161346863
| 2,468
|
Corneal opacity
| 13
| 42
| 2.338205
| 0.019377
|
Q06136,O43505,O75844,Q13510,Q5H8A4,P04062,P10619,P16278,P06280,Q9Y4P3,O75569,P04066,P53701
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,344,36,361,142,236,81,18,339,190,220,310,96
|
729,1189,344,779,752,1828,907,220,36,1300,535,1609,236,310,339,1894,81,18,813,1573,576,666,396,638,494,96,844,1311,1209,2435,98,2335,361,1137,1215,543,142,2103,1261,942,2054,190
|
0.3256911134093675,-0.033074608598505244,0.8200789823454424,0.27676037958362715,0.3013170110599651,-0.5271658967301447,0.17666003360338126,1.1738760097490326,2.868122282262257,-0.11523365842189977,0.5372180454514659,-0.34455645734238355,1.117653769245169,0.9224673008330843,0.8408260074769911,-0.590226648688484,2.1599235408173723,3.1754755052007098,0.25201882658425456,-0.3150370549937861,0.49139101679695213,0.3977415176858454,0.7356968204452725,0.42140856532916043,0.6047569844332618,1.9679892965036938,0.22708991471684983,-0.11523365842189977,-0.033074608598505244,-2.3553677588654476,1.9251128862095315,-1.3299025873109733,0.7991941651751763,0.020605480698360126,-0.033074608598505244,0.5372180454514659,1.5895402794086952,-0.7864806683003362,-0.06023936284890438,0.17666003360338126,-0.7198459356446938,1.2833019254548965
| 2,468
|
Er to golgi anterograde transport
| 30
| 63
| 2.336242
| 0.019479
|
P24390,P35606,Q9Y678,Q15436,Q15363,P68371,O14653,Q9BVA1,Q13561,P49755,Q14789,Q13813,P04350,Q9BUF5,Q9HCU5,Q12893,Q92538,Q9UJW0,Q08379,Q13885,Q9BVK6,P63167,Q9Y3B3,Q9Y3Q3,Q14203,Q99747,O75935,P62820,P49257,P61923
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
5,291,295,304,698,312,683,458,328,692,584,582,333,726,481,350,476,355,471,618,747,737,367,368,498,501,108,359,119,764
|
1336,750,683,870,1407,1681,1476,2086,108,1523,333,1528,5,291,2123,1203,817,881,119,692,1243,1126,843,1537,1971,1063,764,359,737,312,1030,471,350,1741,1650,923,1622,328,582,618,498,1213,584,698,304,1847,1110,1460,476,1950,1327,1551,501,726,458,747,1597,481,355,367,368,295,1082
|
-0.1430695347463049,0.3013170110599651,0.3739010819588171,0.20197116058474252,-0.1994350717264357,-0.4043641190777143,-0.2567482190180186,-0.7864806683003362,1.8373833245061917,-0.2857688748733796,0.8614368152158327,-0.2857688748733796,3.8314985860427604,0.9625009483378237,-0.8202718560579666,-0.033074608598505244,0.25201882658425456,0.20197116058474252,1.7468979457042964,0.3739010819588171,-0.06023936284890438,0.020605480698360126,0.22708991471684983,-0.2857688748733796,-0.65444091817572,0.07343946733113242,0.3013170110599651,0.7991941651751763,0.3256911134093675,0.9224673008330843,0.09954637705818221,0.6269572845849924,0.8200789823454424,-0.4346601796282852,-0.3743308591385381,0.17666003360338126,-0.34455645734238355,0.8819129546814536,0.49139101679695213,0.44490440798943937,0.6047569844332618,-0.033074608598505244,0.49139101679695213,0.3739010819588171,0.9425484828699386,-0.5271658967301447,0.047126781746465576,-0.22797146657486117,0.6269572845849924,-0.6221873063453945,-0.11523365842189977,-0.2857688748733796,0.6047569844332618,0.34988503514948976,0.6490043765907978,0.3256911134093675,-0.3150370549937861,0.6269572845849924,0.8200789823454424,0.7991941651751763,0.7991941651751763,0.9625009483378237,0.07343946733113242
| 2,468
|
Signaling by notch4
| 14
| 41
| 2.336229
| 0.019479
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,1029,470,821,695,2134,2269,499,1665,164,1177,147,1265,869
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.09954637705818221,0.6269572845849924,0.25201882658425456,0.3739010819588171,-0.8202718560579666,-1.1026963504909864,0.6047569844332618,-0.3743308591385381,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438,0.22708991471684983
| 2,468
|
Connective tissue development
| 10
| 18
| 2.335838
| 0.0195
|
Q8N0X7,P11802,P35610,O75844,P43490,Q96EB6,P16435,Q9BZK7,Q92896,O15173
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
320,223,255,36,106,398,245,265,94,126
|
126,36,1965,223,245,2315,1198,1533,255,106,1969,451,1879,320,94,398,701,265
|
1.6535024833174539,2.868122282262257,-0.65444091817572,1.1552498319919475,1.0795911798832665,-1.2525962685132521,-0.033074608598505244,-0.2857688748733796,1.0603817720347808,1.8521923010037062,-0.65444091817572,0.6490043765907978,-0.5585543448403263,0.9022559500015589,1.9821392383520264,0.7356968204452725,0.3739010819588171,1.0603817720347808
| 2,468
|
Azurophil granule lumen
| 9
| 34
| 2.33556
| 0.019514
|
O00584,P15586,Q99536,P07437,P16278,P10619,Q9BTY2,P68371,P04066
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
281,325,235,299,18,81,152,312,310
|
281,729,1637,1683,310,339,1829,299,536,81,1302,325,18,609,634,1694,1579,819,1027,1244,1699,735,312,497,1248,1806,1213,1628,827,1430,1177,235,152,531
|
0.9823261264765617,0.3256911134093675,-0.3743308591385381,-0.4043641190777143,0.9224673008330843,0.8408260074769911,-0.5271658967301447,0.9425484828699386,0.5372180454514659,2.1599235408173723,-0.11523365842189977,0.8819129546814536,3.1754755052007098,0.44490440798943937,0.42140856532916043,-0.4043641190777143,-0.3150370549937861,0.25201882658425456,0.09954637705818221,-0.06023936284890438,-0.4043641190777143,0.3256911134093675,0.9224673008330843,0.6047569844332618,-0.06023936284890438,-0.4960569056469889,-0.033074608598505244,-0.34455645734238355,0.25201882658425456,-0.1994350717264357,-0.006127331605984542,1.1365094929601929,1.5075840575864408,0.5598892765754294
| 2,468
|
Abnormal conjunctiva morphology
| 9
| 24
| 2.332985
| 0.019649
|
Q9NZ08,P50851,P28070,Q14739,Q13510,P10619,Q15437,P06280,P04066
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
427,193,225,139,361,81,279,339,310
|
1727,432,310,1964,339,81,982,813,1573,957,986,225,1491,2062,1094,2064,193,1314,361,139,279,1002,1184,427
|
-0.4346601796282852,0.6709000913867084,0.9224673008330843,-0.65444091817572,0.8408260074769911,2.1599235408173723,0.1254502957539166,0.25201882658425456,-0.3150370549937861,0.15115395482942545,0.1254502957539166,1.1552498319919475,-0.2567482190180186,-0.7530070814189461,0.047126781746465576,-0.7530070814189461,1.2653360299982175,-0.11523365842189977,0.7991941651751763,1.6056618506283145,1.0020254240102997,0.1254502957539166,-0.006127331605984542,0.692646228876154
| 2,468
|
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
| 6
| 20
| 2.33261
| 0.019669
|
P35606,P24390,Q8TD16,O15258,Q9Y282,Q9P2W9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
291,5,206,208,21,288
|
750,208,2086,1528,1574,5,291,881,691,692,843,764,350,1741,1131,206,1460,476,288,21
|
0.3013170110599651,1.2107906833937936,-0.7864806683003362,-0.2857688748733796,-0.3150370549937861,3.8314985860427604,0.9625009483378237,0.20197116058474252,0.3739010819588171,0.3739010819588171,0.22708991471684983,0.3013170110599651,0.8200789823454424,-0.4346601796282852,0.020605480698360126,1.2290815354843998,-0.22797146657486117,0.6269572845849924,0.9823261264765617,3.129814463490708
| 2,468
|
Sphingolipid metabolism integrated pathway
| 6
| 7
| 2.33126
| 0.01974
|
Q06136,O95470,Q96G23,O15269,O15121,Q16739
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
98,269,114,153,218,92
|
218,153,269,98,361,92,114
|
1.1738760097490326,1.4909169970454357,1.0216002256059087,1.9251128862095315,0.7991941651751763,2.024171009993822,1.807535106013106
| 2,468
|
Sphingolipid metabolism overview
| 6
| 7
| 2.33126
| 0.01974
|
Q06136,O95470,Q96G23,O15269,O15121,Q16739
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
98,269,114,153,218,92
|
218,153,269,98,361,92,114
|
1.1738760097490326,1.4909169970454357,1.0216002256059087,1.9251128862095315,0.7991941651751763,2.024171009993822,1.807535106013106
| 2,468
|
Proteolysis
| 76
| 306
| 2.326093
| 0.020014
|
Q16763,Q96BN8,Q10713,Q8N163,A4D1P6,O00231,P42785,Q96FW1,Q9UHG3,P52888,O14773,Q96EB6,Q5JRX3,Q9Y263,Q9UL46,P55786,O75976,P49427,Q86UV5,P60900,P50579,P09960,A0AVT1,Q9NZ08,P61201,O75844,Q99436,Q8N668,P42892,P40763,O14737,P67812,Q4J6C6,Q96KC8,P19474,O95831,Q8IYS1,Q8TCT9,P49721,P61289,P28074,Q9UIQ6,P22695,P23396,Q15392,Q9UBU6,O75503,P09429,Q9HB40,P49841,Q9H3G5,P20618,P07858,P10619,Q9UPU5,Q9Y5A7,Q92896,P24941,P28070,O43847,P49720,Q99816,Q9BT78,Q92688,Q5VTR2,P04062,Q8IXJ6,Q9NR09,Q9UNN5,P16435,O75150,Q9BYT8,P46379,Q9BZK7,P28072,Q92905
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
260,388,257,386,130,251,8,399,10,12,141,398,272,145,147,23,276,407,410,408,28,283,159,427,163,36,164,292,39,416,413,173,174,442,50,298,440,314,56,436,54,58,59,311,61,65,66,319,68,327,74,202,80,81,212,343,94,224,225,345,230,365,105,364,362,236,109,110,381,245,370,250,123,265,373,263
|
159,130,251,682,2221,1335,413,141,1226,836,684,572,533,504,657,345,1084,2195,370,2402,1229,1606,1961,66,1412,1640,36,2056,276,2154,1192,1339,298,1271,432,236,1924,2027,1758,781,2198,1301,1829,1644,80,956,319,1685,1021,283,1483,81,2324,2416,1235,1376,873,245,1155,756,50,1303,202,2449,984,1927,59,311,224,1059,1532,1158,1305,2030,1237,1199,225,373,54,2334,2031,733,2060,1575,2033,1492,2062,1533,597,1872,879,1696,2063,416,2035,539,8,39,1240,1161,123,1092,1899,2411,1093,1124,1094,407,763,230,56,692,2124,327,1969,28,1735,557,2317,12,1616,1244,1061,558,994,1699,23,2318,408,2174,1350,163,436,1385,2398,1972,845,1279,884,2006,1739,737,470,1453,173,1247,738,601,1313,821,257,1455,1281,1132,1805,695,1806,1421,617,1065,676,2269,1249,793,1387,794,583,2044,1167,2215,1136,499,795,1655,1656,1034,1909,927,61,2099,1389,890,455,260,174,2102,272,1942,2048,1706,362,1457,1547,1510,562,930,1356,1107,1285,2466,410,1511,109,440,386,1109,292,2408,1001,1287,1393,314,621,1590,1665,2166,895,364,2273,827,896,94,263,2106,623,828,513,1256,724,1142,2342,897,388,1430,398,1326,399,1463,701,898,515,932,442,2108,1746,164,1177,1630,1986,1114,365,1910,934,105,1717,2050,250,265,680,1005,703,773,1396,74,1007,1748,68,1862,940,110,604,2387,1671,2112,427,628,1044,2080,65,681,10,58,710,1013,774,1263,1331,1634,147,630,2055,651,1265,381,944,212,1917,145,2278,2150,867,343,1475,2253,1790,1918
|
1.457299817470005,1.6376421273678423,1.0603817720347808,0.3739010819588171,-0.994181179090294,-0.1430695347463049,0.692646228876154,1.5895402794086952,-0.06023936284890438,0.22708991471684983,0.3739010819588171,0.49139101679695213,0.5372180454514659,0.58240161346863,0.3977415176858454,0.8200789823454424,0.047126781746465576,-0.9236044800386676,0.7781699552447922,-1.742458928246437,-0.06023936284890438,-0.34455645734238355,-0.65444091817572,2.3395309528321633,-0.1994350717264357,-0.3743308591385381,2.868122282262257,-0.7530070814189461,1.0020254240102997,-0.8543859267849101,-0.033074608598505244,-0.1430695347463049,0.9425484828699386,-0.08762466761145592,0.6709000913867084,1.117653769245169,-0.6221873063453945,-0.7198459356446938,-0.46522306940850683,0.27676037958362715,-0.9236044800386676,-0.11523365842189977,-0.5271658967301447,-0.3743308591385381,2.1599235408173723,0.15115395482942545,0.9022559500015589,-0.4043641190777143,0.09954637705818221,0.9823261264765617,-0.2567482190180186,2.1599235408173723,-1.2910471139088535,-1.9209411773807756,-0.06023936284890438,-0.17113556168396907,0.20197116058474252,1.0795911798832665,-0.006127331605984542,0.3013170110599651,2.5658905492788504,-0.11523365842189977,1.2290815354843998,-3.078970856737308,0.1254502957539166,-0.6221873063453945,2.461011602486414,0.9224673008330843,1.1552498319919475,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.7198459356446938,-0.06023936284890438,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-1.3299025873109733,-0.7198459356446938,0.3256911134093675,-0.7530070814189461,-0.3150370549937861,-0.7198459356446938,-0.2567482190180186,-0.7530070814189461,-0.2857688748733796,0.4682311897943023,-0.5585543448403263,0.20197116058474252,-0.4043641190777143,-0.7530070814189461,0.692646228876154,-0.7198459356446938,0.5372180454514659,3.5056872507526013,2.827005651000117,-0.06023936284890438,-0.006127331605984542,1.6692773995529553,0.047126781746465576,-0.590226648688484,-1.83066113592861,0.047126781746465576,0.020605480698360126,0.047126781746465576,0.7142445586094798,0.3013170110599651,1.1365094929601929,2.4964247239663777,0.3739010819588171,-0.8202718560579666,0.8819129546814536,-0.65444091817572,2.928608323075618,-0.4346601796282852,0.5143859578494419,-1.2525962685132521,3.4332901983397086,-0.34455645734238355,-0.06023936284890438,0.07343946733113242,0.5143859578494419,0.1254502957539166,-0.4043641190777143,3.0739178449056257,-1.2525962685132521,0.7142445586094798,-0.8888282886905626,-0.1430695347463049,1.4403478303991744,0.6709000913867084,-0.17113556168396907,-1.6562527119273847,-0.65444091817572,0.22708991471684983,-0.08762466761145592,0.20197116058474252,-0.6869921898793442,-0.4346601796282852,0.3256911134093675,0.6269572845849924,-0.22797146657486117,1.3365673787376733,-0.06023936284890438,0.3256911134093675,0.4682311897943023,-0.11523365842189977,0.25201882658425456,1.0603817720347808,-0.22797146657486117,-0.08762466761145592,0.020605480698360126,-0.4960569056469889,0.3739010819588171,-0.4960569056469889,-0.1994350717264357,0.44490440798943937,0.07343946733113242,0.3977415176858454,-1.1026963504909864,-0.06023936284890438,0.27676037958362715,-0.17113556168396907,0.27676037958362715,0.49139101679695213,-0.7198459356446938,-0.006127331605984542,-0.958720173237647,0.020605480698360126,0.6047569844332618,0.27676037958362715,-0.3743308591385381,-0.3743308591385381,0.09954637705818221,-0.590226648688484,0.17666003360338126,2.4130652487639477,-0.7864806683003362,-0.17113556168396907,0.20197116058474252,0.6490043765907978,1.0603817720347808,1.3365673787376733,-0.7864806683003362,1.0216002256059087,-0.6221873063453945,-0.7198459356446938,-0.4043641190777143,0.7991941651751763,-0.22797146657486117,-0.2857688748733796,-0.2567482190180186,0.5143859578494419,0.17666003360338126,-0.1430695347463049,0.047126781746465576,-0.08762466761145592,-6.7968678340503486,0.7142445586094798,-0.2567482190180186,1.8224978231489162,0.6709000913867084,0.7570047251940325,0.047126781746465576,0.9625009483378237,-1.7863055278776567,0.1254502957539166,-0.08762466761145592,-0.17113556168396907,0.9224673008330843,0.44490440798943937,-0.3150370549937861,-0.3743308591385381,-0.8543859267849101,0.20197116058474252,0.7991941651751763,-1.1026963504909864,0.25201882658425456,0.20197116058474252,1.9821392383520264,1.0603817720347808,-0.7864806683003362,0.44490440798943937,0.25201882658425456,0.58240161346863,-0.06023936284890438,0.34988503514948976,0.020605480698360126,-1.3299025873109733,0.20197116058474252,0.7570047251940325,-0.1994350717264357,0.7356968204452725,-0.11523365842189977,0.7356968204452725,-0.22797146657486117,0.3739010819588171,0.20197116058474252,0.58240161346863,0.17666003360338126,0.6709000913867084,-0.7864806683003362,-0.4346601796282852,1.4232989777185565,-0.006127331605984542,-0.34455645734238355,-0.65444091817572,0.047126781746465576,0.7991941651751763,-0.590226648688484,0.17666003360338126,1.8669254347810549,-0.4043641190777143,-0.7198459356446938,1.0795911798832665,1.0603817720347808,0.3977415176858454,0.1254502957539166,0.3739010819588171,0.3013170110599651,-0.17113556168396907,2.2254112620780373,0.1254502957539166,-0.4346601796282852,2.3270814179529142,-0.5271658967301447,0.17666003360338126,1.8224978231489162,0.4682311897943023,-1.5719651640648913,-0.3743308591385381,-0.7864806683003362,0.692646228876154,0.44490440798943937,0.09954637705818221,-0.7530070814189461,2.351924388044598,0.3977415176858454,3.489782484645634,2.4728673792906726,0.3739010819588171,0.1254502957539166,0.3013170110599651,-0.06023936284890438,-0.11523365842189977,-0.34455645734238355,1.5406396934742081,0.44490440798943937,-0.7198459356446938,0.42140856532916043,-0.06023936284890438,0.7781699552447922,0.17666003360338126,1.2107906833937936,-0.590226648688484,1.5570300603921419,-1.1026963504909864,-0.8202718560579666,0.22708991471684983,0.8408260074769911,-0.22797146657486117,-1.0299934512102915,-0.46522306940850683,-0.590226648688484
| 2,468
|
Liposaccharide metabolic process
| 8
| 15
| 2.324439
| 0.020102
|
Q8NBX0,P04062,Q5H8A4,Q99805,P06865,P16278,Q16739,P04066
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,236,142,180,209,18,92,310
|
236,310,339,209,536,18,609,92,142,33,895,2230,2410,180,1598
|
1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,0.5372180454514659,3.1754755052007098,0.44490440798943937,2.024171009993822,1.5895402794086952,2.908601987092757,0.20197116058474252,-0.994181179090294,-1.7863055278776567,1.3189165219976549,-0.3150370549937861
| 2,468
|
Receptor
| 8
| 29
| 2.322362
| 0.020213
|
Q8WTV0,P24390,Q14739,Q14108,P35613,Q9NS69,P11717,O15173
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
38,5,139,84,214,29,221,126
|
570,977,126,1412,432,1963,781,1925,1233,1483,1484,221,873,5,214,579,1765,84,139,1544,2446,38,1325,1256,2288,443,29,1957,268
|
0.49139101679695213,0.1254502957539166,1.6535024833174539,-0.1994350717264357,0.6709000913867084,-0.65444091817572,0.27676037958362715,-0.6221873063453945,-0.06023936284890438,-0.2567482190180186,-0.2567482190180186,1.1738760097490326,0.20197116058474252,3.8314985860427604,1.192389231232484,0.49139101679695213,-0.46522306940850683,2.119881427808456,1.6056618506283145,-0.2857688748733796,-2.959510953601851,2.857903513986415,-0.11523365842189977,-0.06023936284890438,-1.139599641176551,0.6709000913867084,2.928608323075618,-0.6221873063453945,1.0410518943199942
| 2,468
|
Glycosidase
| 6
| 15
| 2.316933
| 0.020507
|
P04062,P06865,P16278,Q9BTY2,O60502,P04066
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
236,209,18,152,25,310
|
729,2193,25,236,310,339,209,536,1234,18,759,693,1623,1767,152
|
0.3256911134093675,-0.9236044800386676,2.9583317443973955,1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,0.5372180454514659,-0.06023936284890438,3.1754755052007098,0.3013170110599651,0.3739010819588171,-0.34455645734238355,-0.46522306940850683,1.5075840575864408
| 2,468
|
Phenotypic variability
| 32
| 79
| 2.307212
| 0.021043
|
Q70HW3,O95470,P38606,Q9Y263,Q9Y3Z3,Q9UEY8,P07602,O00429,O43707,Q12756,P43034,P49736,O60313,Q9BVA1,Q9H061,Q13813,Q8TD16,P00403,O14979,P04350,P00374,P06753,O15121,Q13885,P52701,Q9NZJ7,P33993,Q9NQT5,P52732,Q13510,Q9UBB4,P11166
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,269,524,145,552,551,31,412,297,437,556,435,553,458,70,582,206,324,200,333,79,447,218,618,348,628,468,626,494,361,380,491
|
412,200,218,297,553,2154,837,2367,269,79,324,1609,333,447,31,1232,1685,491,609,957,468,1533,2438,879,2120,524,1613,1382,556,990,1204,435,1383,959,1205,348,494,719,1699,1498,1451,846,847,849,437,2404,361,582,1066,618,1166,1767,2009,1105,1943,1547,1945,1548,3,206,1323,1039,726,458,70,1077,626,901,1558,628,380,1864,551,807,145,1371,552,2150,868
|
0.692646228876154,1.2290815354843998,1.1738760097490326,0.9425484828699386,0.5143859578494419,-0.8543859267849101,0.22708991471684983,-1.4489724671135231,1.0216002256059087,2.1599235408173723,0.8819129546814536,-0.34455645734238355,0.8614368152158327,0.6490043765907978,2.908601987092757,-0.06023936284890438,-0.4043641190777143,0.6047569844332618,0.44490440798943937,0.15115395482942545,0.6269572845849924,-0.2857688748733796,-2.406736711092555,0.20197116058474252,-0.8202718560579666,0.5598892765754294,-0.34455645734238355,-0.17113556168396907,0.5143859578494419,0.1254502957539166,-0.033074608598505244,0.6709000913867084,-0.17113556168396907,0.15115395482942545,-0.033074608598505244,0.8200789823454424,0.6047569844332618,0.34988503514948976,-0.4043641190777143,-0.2567482190180186,-0.22797146657486117,0.22708991471684983,0.22708991471684983,0.22708991471684983,0.6709000913867084,-1.742458928246437,0.7991941651751763,0.49139101679695213,0.07343946733113242,0.44490440798943937,-0.006127331605984542,-0.46522306940850683,-0.6869921898793442,0.047126781746465576,-0.6221873063453945,-0.2857688748733796,-0.6221873063453945,-0.2857688748733796,4.09320199924866,1.2290815354843998,-0.11523365842189977,0.09954637705818221,0.34988503514948976,0.6490043765907978,2.2893917554224728,0.07343946733113242,0.44490440798943937,0.20197116058474252,-0.2857688748733796,0.44490440798943937,0.7781699552447922,-0.5271658967301447,0.5372180454514659,0.27676037958362715,1.5570300603921419,-0.1430695347463049,0.5372180454514659,-0.8202718560579666,0.22708991471684983
| 2,468
|
Transmembrane transport
| 39
| 175
| 2.306148
| 0.021102
|
Q8TB61,Q15629,Q99595,Q70HW3,P21796,P45880,Q9UDW1,Q9UHG3,Q8IXU6,Q9H2D1,Q6NT16,O75964,P78417,Q9Y277,P23786,Q9NS69,Q8N4V1,P08183,O75844,Q8WTV0,O43772,Q8N668,P53985,Q7L0J3,P52789,Q9HC07,Q9HD20,O95831,P39210,P04920,Q9UBX3,P33527,Q9BPX6,Q9C0H2,P04062,P62942,Q13423,Q9BZF1,Q9Y619
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,259,2,3,4,7,136,10,13,14,15,143,271,275,26,29,286,32,36,38,37,292,40,41,303,307,47,298,176,187,199,75,217,89,236,238,117,264,125
|
1333,2023,1567,2151,485,503,297,37,534,505,1052,1054,1728,1921,2323,2264,907,1606,1411,36,2056,2225,143,1477,1300,1121,298,1019,324,236,187,981,1642,2157,1963,1480,1829,1644,1965,32,1481,2057,537,608,1572,2324,491,2463,811,1612,1154,434,1155,1690,2255,914,2171,1379,4,394,26,757,2211,2059,1380,1490,2212,1966,663,1835,75,666,1871,1346,1534,524,176,7,2266,2427,692,2124,1497,2392,303,2066,40,2283,1245,2298,2068,2318,1206,1702,2399,996,238,271,2008,2070,601,1803,998,848,451,2072,1650,117,1422,453,999,1655,797,1283,259,1544,890,456,1507,15,2103,1141,1945,3,41,2328,13,2450,286,292,2181,128,2340,38,1256,2011,624,1463,969,1986,2,2288,342,217,1715,1718,1778,264,89,863,14,1366,1433,1633,2017,307,834,47,1042,29,199,136,1560,903,10,1117,1297,1263,1563,275,518,1992,1404,2150,125
|
-0.1430695347463049,-0.7198459356446938,-0.3150370549937861,-0.8543859267849101,0.6047569844332618,0.58240161346863,0.9425484828699386,2.857903513986415,0.5372180454514659,0.58240161346863,0.07343946733113242,0.07343946733113242,-0.4346601796282852,-0.6221873063453945,-1.2910471139088535,-1.1026963504909864,0.17666003360338126,-0.34455645734238355,-0.1994350717264357,2.868122282262257,-0.7530070814189461,-0.994181179090294,1.5733299672243768,-0.2567482190180186,-0.11523365842189977,0.020605480698360126,0.9425484828699386,0.09954637705818221,0.8819129546814536,1.117653769245169,1.2833019254548965,0.1254502957539166,-0.3743308591385381,-0.8543859267849101,-0.65444091817572,-0.2567482190180186,-0.5271658967301447,-0.3743308591385381,-0.65444091817572,2.908601987092757,-0.2567482190180186,-0.7530070814189461,0.5372180454514659,0.44490440798943937,-0.3150370549937861,-1.2910471139088535,0.6047569844332618,-4.145163584141374,0.25201882658425456,-0.34455645734238355,-0.006127331605984542,0.6709000913867084,-0.006127331605984542,-0.4043641190777143,-1.066163090613305,0.17666003360338126,-0.8888282886905626,-0.17113556168396907,3.838410894509741,0.7356968204452725,2.9583317443973955,0.3013170110599651,-0.958720173237647,-0.7530070814189461,-0.17113556168396907,-0.2567482190180186,-0.958720173237647,-0.65444091817572,0.3977415176858454,-0.5271658967301447,2.199400481282764,0.3977415176858454,-0.5585543448403263,-0.1430695347463049,-0.2857688748733796,0.5598892765754294,1.3189165219976549,3.6667004853346468,-1.1026963504909864,-2.156313870988057,0.3739010819588171,-0.8202718560579666,-0.2567482190180186,-1.6138737694884546,0.9425484828699386,-0.7530070814189461,2.827005651000117,-1.139599641176551,-0.06023936284890438,-1.1768795353111265,-0.7530070814189461,-1.2525962685132521,-0.033074608598505244,-0.4043641190777143,-1.6562527119273847,0.1254502957539166,1.117653769245169,1.0216002256059087,-0.6869921898793442,-0.7530070814189461,0.4682311897943023,-0.4960569056469889,0.1254502957539166,0.22708991471684983,0.6490043765907978,-0.7530070814189461,-0.3743308591385381,1.7773752159481948,-0.1994350717264357,0.6490043765907978,0.1254502957539166,-0.3743308591385381,0.27676037958362715,-0.08762466761145592,1.0603817720347808,-0.2857688748733796,0.20197116058474252,0.6490043765907978,-0.2567482190180186,3.3248211178078995,-0.7864806683003362,0.020605480698360126,-0.6221873063453945,4.09320199924866,2.827005651000117,-1.2910471139088535,3.383816314422708,-3.078970856737308,0.9823261264765617,0.9625009483378237,-0.8888282886905626,1.6535024833174539,-1.3299025873109733,2.857903513986415,-0.06023936284890438,-0.6869921898793442,0.44490440798943937,-0.22797146657486117,0.15115395482942545,-0.65444091817572,4.0993803881071775,-1.139599641176551,0.8408260074769911,1.192389231232484,-0.4043641190777143,-0.4043641190777143,-0.46522306940850683,1.0603817720347808,2.0518497400362734,0.22708991471684983,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,-0.6869921898793442,0.9425484828699386,0.25201882658425456,2.6224404188956902,0.09954637705818221,2.928608323075618,1.2472629393969026,1.6216955230183503,-0.2857688748733796,0.20197116058474252,3.489782484645634,0.047126781746465576,-0.08762466761145592,-0.06023936284890438,-0.2857688748733796,1.0216002256059087,0.58240161346863,-0.65444091817572,-0.17113556168396907,-0.8202718560579666,1.6692773995529553
| 2,468
|
Proteasome core complex beta subunit complex
| 6
| 7
| 2.301432
| 0.021367
|
P28070,Q99436,P49720,P20618,P49721,P28074
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
225,164,230,202,56,54
|
202,225,373,54,230,56,164
|
1.2290815354843998,1.1552498319919475,0.7781699552447922,2.4964247239663777,1.1365094929601929,2.4964247239663777,1.4232989777185565
| 2,468
|
Proteasome B-type subunit [IPR023333]
| 6
| 7
| 2.301432
| 0.021367
|
P28070,Q99436,P49720,P20618,P49721,P28074
|
Sequence
|
InterPro Family
|
interpro_family
|
225,164,230,202,56,54
|
202,225,373,54,230,56,164
|
1.2290815354843998,1.1552498319919475,0.7781699552447922,2.4964247239663777,1.1365094929601929,2.4964247239663777,1.4232989777185565
| 2,468
|
Contractures of the joints of the upper limbs
| 10
| 50
| 2.300993
| 0.021392
|
P37268,O75844,P42892,Q15042,Q7LGA3,P27635,P16435,Q9Y619,P23786,Q15392
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,36,39,233,204,83,245,125,26,61
|
778,1189,949,906,36,1609,447,245,813,1379,984,26,83,634,2061,878,131,39,690,818,2065,844,1451,1209,1454,1387,1422,1583,1908,1504,233,61,1284,1981,204,285,967,1855,2459,1666,514,1516,746,443,1179,2301,1789,391,125,947
|
0.27676037958362715,-0.033074608598505244,0.15115395482942545,0.17666003360338126,2.868122282262257,-0.34455645734238355,0.6490043765907978,1.0795911798832665,0.25201882658425456,-0.17113556168396907,0.1254502957539166,2.9583317443973955,2.119881427808456,0.42140856532916043,-0.7530070814189461,0.20197116058474252,1.6376421273678423,2.827005651000117,0.3739010819588171,0.25201882658425456,-0.7530070814189461,0.22708991471684983,-0.22797146657486117,-0.033074608598505244,-0.22797146657486117,-0.17113556168396907,-0.1994350717264357,-0.3150370549937861,-0.590226648688484,-0.2567482190180186,1.1365094929601929,2.4130652487639477,-0.08762466761145592,-0.65444091817572,1.2290815354843998,0.9823261264765617,0.15115395482942545,-0.5271658967301447,-3.5210304314857104,-0.3743308591385381,0.58240161346863,-0.2567482190180186,0.3256911134093675,0.6709000913867084,-0.006127331605984542,-1.1768795353111265,-0.46522306940850683,0.7570047251940325,1.6692773995529553,0.17666003360338126
| 2,468
|
Abnormality of the septum pellucidum
| 16
| 33
| 2.283697
| 0.022389
|
Q9BVA1,O43505,O96028,P28482,Q9NVI1,Q8WWQ0,Q08J23,P49591,Q96F86,Q96C86,Q96N66,Q69YQ0,P43034,Q15392,P53701,Q9NZ01
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
458,344,535,634,402,529,616,270,564,336,647,241,556,61,96,161
|
949,344,1084,1300,535,913,634,556,270,1309,96,1245,616,1130,1622,925,61,241,1659,1173,529,336,564,647,458,861,1780,2387,402,161,902,904,713
|
0.15115395482942545,0.8200789823454424,0.047126781746465576,-0.11523365842189977,0.5372180454514659,0.17666003360338126,0.42140856532916043,0.5143859578494419,1.0216002256059087,-0.11523365842189977,1.9679892965036938,-0.06023936284890438,0.44490440798943937,0.020605480698360126,-0.34455645734238355,0.17666003360338126,2.4130652487639477,1.0986814186639104,-0.3743308591385381,-0.006127331605984542,0.5598892765754294,0.8614368152158327,0.5143859578494419,0.42140856532916043,0.6490043765907978,0.22708991471684983,-0.46522306940850683,-1.5719651640648913,0.7356968204452725,1.457299817470005,0.20197116058474252,0.20197116058474252,0.3739010819588171
| 2,468
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 11
| 25
| 2.275036
| 0.022904
|
Q6P6C2,Q9H6W3,Q16850,P09601,P16435,O15121,Q9BU89,O75151,P30519,Q8NB78,O95864
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
473,99,43,522,245,218,91,430,27,512,282
|
778,1438,218,1920,430,282,1086,522,2375,245,1999,27,736,1454,1281,541,619,43,1035,473,1036,512,91,99,1676
|
0.27676037958362715,-0.22797146657486117,1.1738760097490326,-0.6221873063453945,0.6709000913867084,0.9823261264765617,0.047126781746465576,0.5598892765754294,-1.4895231624354457,1.0795911798832665,-0.6869921898793442,2.928608323075618,0.3256911134093675,-0.22797146657486117,-0.08762466761145592,0.5372180454514659,0.44490440798943937,2.7427903084146905,0.09954637705818221,0.6269572845849924,0.09954637705818221,0.58240161346863,2.03804423097585,1.9251128862095315,-0.3743308591385381
| 2,468
|
Nitrogen compound transport
| 109
| 454
| 2.274927
| 0.02291
|
A6NIH7,Q99595,O43865,P24390,O43633,O43615,Q9H2D1,Q9Y282,P55786,Q9NS69,P07602,P08183,O43772,P53985,Q7L0J3,Q16850,O60725,Q9HD20,P30536,P33527,P10619,Q14108,P50897,P49257,P46379,Q9Y619,O15173,Q8TB61,P43307,Q7Z4Q2,Q9BTX1,Q96PU8,Q15154,P63241,Q9H269,Q4J6C6,Q8NFH4,P09132,Q8N4H5,Q8TD16,O00170,Q8IYI6,Q14C86,Q15042,P53367,Q92544,Q15629,Q10713,Q9Y5M8,Q5JRX3,Q9H270,Q9Y277,Q15437,Q9P2W9,Q15904,P35606,Q8N668,Q92973,Q9Y678,Q15436,P17858,O95831,O15397,O43707,Q8TCT9,O75312,Q9Y2T2,P49841,Q99808,Q12893,P27348,Q9Y3Q3,Q9Y3B3,Q99816,Q92688,P62820,A0AVF1,P31689,Q8TEX9,P40855,Q8N1F7,Q9UNH7,P21359,P67809,P40763,O14737,O00429,Q96KC8,P02786,O75436,Q9UHB9,Q9H267,Q3ZCQ8,Q06124,Q9H6U6,Q92945,Q9HCU5,Q92538,Q86Y82,Q08379,Q6P6C2,O60749,Q99747,Q9UPT5,O14925,O14964,O15126,Q9UL25,Q9Y289
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,2,505,5,504,503,14,21,23,29,31,32,37,40,41,43,44,47,73,75,81,84,112,119,123,125,126,128,132,134,144,156,165,171,172,174,179,192,198,206,207,211,232,233,237,242,259,257,268,272,274,275,279,288,284,291,292,293,295,304,300,298,296,297,314,318,332,327,342,350,346,368,367,365,364,359,356,374,387,396,423,428,415,420,416,413,412,442,432,431,462,459,456,451,480,477,481,476,474,471,473,464,501,502,485,487,488,517,518
|
356,1,1333,1334,1791,2113,207,2023,835,520,1015,412,1825,655,750,1119,683,413,751,485,487,836,1407,488,978,126,296,2083,1681,1754,1725,503,504,1637,297,1793,1726,657,1150,37,534,505,952,1638,753,44,464,1476,2195,1054,1728,2085,1120,318,2402,1229,907,2086,431,1606,1267,1374,1411,2056,1756,573,1477,2197,1682,1523,1018,837,1268,1193,1339,1121,1996,2156,298,1019,1730,1609,432,1757,1758,1570,1642,2157,660,1963,781,2028,31,732,32,1481,1232,956,1925,192,1831,1893,537,81,2324,1445,811,1612,574,1686,1376,1196,913,1155,300,1197,1447,1528,1303,1530,662,1574,1379,415,1797,1304,5,2059,346,1380,2030,1237,2296,1381,73,1966,1493,374,555,815,75,1090,597,664,291,1695,2091,1930,612,2282,2316,416,396,1275,760,1347,1578,556,132,1200,123,2123,881,119,637,762,763,692,2347,1383,2124,327,1579,818,1497,112,1836,1934,960,1735,669,842,509,918,1616,1736,237,1126,843,1278,40,1244,1537,1971,1245,670,1699,23,1451,2068,2318,2004,1737,1206,2159,2304,1701,2399,764,600,996,359,961,2006,1739,1740,1029,171,1453,420,1247,1841,1801,739,2008,601,847,1030,998,848,451,889,2042,1906,471,850,616,1618,1314,257,1102,1874,350,1130,1741,1650,1842,923,1282,1875,1742,1211,84,2377,1134,1135,1214,2284,232,1136,1655,233,560,165,2074,797,698,1283,304,279,259,1846,1544,1506,284,769,585,2348,2378,1139,824,43,1035,456,174,1105,1847,272,1942,1508,2103,1945,473,1459,41,562,1848,857,134,1285,2361,1812,2309,2458,474,211,423,198,893,292,1110,2181,2285,179,1773,2310,1001,128,2340,314,206,1854,387,967,621,1460,529,476,242,1111,1175,364,896,1856,477,293,1176,724,1002,1430,2299,1550,1857,1514,624,1745,442,1221,1551,156,1629,1713,2409,969,1630,1986,746,1178,2,2288,501,342,365,934,144,1717,747,1747,2016,1778,1004,1553,861,2301,1597,459,172,274,14,1366,727,1396,1182,2232,480,970,1397,1433,1633,650,2017,834,481,47,1042,1145,2251,1817,941,1722,29,1863,1147,1784,1369,628,1916,1821,288,866,1600,2208,681,2292,1560,462,903,1400,1370,1786,1989,1297,1956,1753,517,1562,1472,651,1264,428,2365,749,502,1917,1332,275,21,518,332,1403,946,367,368,2293,1404,1405,1372,2253,268,1790,125,295,1918,595
|
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| 2,468
|
Response to oxygen levels
| 21
| 52
| 2.271943
| 0.02309
|
Q8N511,Q96EB6,P38606,P55786,Q15904,P30519,P21359,P55061,P52789,Q9Y487,O95831,O43707,Q9Y4P3,P02786,P00813,Q99808,Q6P6C2,Q8IXJ6,Q92544,P11166,O75306
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
6,398,524,23,284,27,415,419,303,181,298,297,190,432,446,342,473,109,242,491,371
|
905,778,297,371,298,1271,446,1609,432,1758,1642,2198,1086,522,491,1376,1573,415,1927,27,875,1696,524,1614,2035,1967,1094,2065,303,419,23,1702,1385,1454,284,2360,473,109,6,1460,242,2273,2342,398,1463,2288,342,1078,2080,181,1679,190
|
0.17666003360338126,0.27676037958362715,0.9425484828699386,0.7781699552447922,0.9425484828699386,-0.08762466761145592,0.6490043765907978,-0.34455645734238355,0.6709000913867084,-0.46522306940850683,-0.3743308591385381,-0.9236044800386676,0.047126781746465576,0.5598892765754294,0.6047569844332618,-0.17113556168396907,-0.3150370549937861,0.692646228876154,-0.6221873063453945,2.928608323075618,0.20197116058474252,-0.4043641190777143,0.5598892765754294,-0.34455645734238355,-0.7198459356446938,-0.65444091817572,0.047126781746465576,-0.7530070814189461,0.9425484828699386,0.692646228876154,3.0739178449056257,-0.4043641190777143,-0.17113556168396907,-0.22797146657486117,0.9823261264765617,-1.4088574939002534,0.6269572845849924,1.8224978231489162,3.681490447648572,-0.22797146657486117,1.0986814186639104,-1.1026963504909864,-1.3299025873109733,0.7356968204452725,-0.22797146657486117,-1.139599641176551,0.8408260074769911,0.07343946733113242,-0.7530070814189461,1.3189165219976549,-0.3743308591385381,1.2833019254548965
| 2,468
|
Metalloprotease
| 13
| 32
| 2.263516
| 0.023604
|
Q9NZ08,O43847,Q10713,O75844,P42892,Q9BYT8,P52888,Q5JRX3,Q8IYS1,P55786,Q9UIQ6,P22695,Q92905
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
427,345,257,36,39,250,12,272,440,23,58,59,263
|
682,2221,572,345,1606,36,432,1273,2416,873,59,2334,663,39,557,12,23,257,1318,272,930,1356,440,2205,263,2106,1746,2343,250,427,58,2150
|
0.3739010819588171,-0.994181179090294,0.49139101679695213,0.8200789823454424,-0.34455645734238355,2.868122282262257,0.6709000913867084,-0.08762466761145592,-1.9209411773807756,0.20197116058474252,2.461011602486414,-1.3299025873109733,0.3977415176858454,2.827005651000117,0.5143859578494419,3.4332901983397086,3.0739178449056257,1.0603817720347808,-0.11523365842189977,1.0216002256059087,0.17666003360338126,-0.1430695347463049,0.6709000913867084,-0.9236044800386676,1.0603817720347808,-0.7864806683003362,-0.4346601796282852,-1.3299025873109733,1.0795911798832665,0.692646228876154,2.4728673792906726,-0.8202718560579666
| 2,468
|
Vacuole organization
| 11
| 42
| 2.259931
| 0.023826
|
P50851,O75503,P11117,Q8N511,Q15042,Q9H269,P04062,O14773,Q9H270,P50897,Q14108
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
193,66,229,6,233,172,236,141,274,112,84
|
835,141,2086,66,1412,837,236,1829,536,1234,229,2210,434,662,1614,193,112,1934,1736,693,1701,359,84,233,2074,2203,474,6,1460,1002,1550,624,1667,1713,1597,172,274,727,307,651,1917,1403
|
0.22708991471684983,1.5895402794086952,-0.7864806683003362,2.3395309528321633,-0.1994350717264357,0.22708991471684983,1.117653769245169,-0.5271658967301447,0.5372180454514659,-0.06023936284890438,1.1365094929601929,-0.958720173237647,0.6709000913867084,0.3977415176858454,-0.34455645734238355,1.2653360299982175,1.807535106013106,-0.6221873063453945,-0.4346601796282852,0.3739010819588171,-0.4043641190777143,0.7991941651751763,2.119881427808456,1.1365094929601929,-0.7530070814189461,-0.9236044800386676,0.6269572845849924,3.681490447648572,-0.22797146657486117,0.1254502957539166,-0.2857688748733796,0.44490440798943937,-0.3743308591385381,-0.4043641190777143,-0.3150370549937861,1.3541153522401639,1.0216002256059087,0.34988503514948976,0.9425484828699386,0.42140856532916043,-0.590226648688484,-0.17113556168396907
| 2,468
|
Auf1 hnrnp d0 binds and destabilizes mrna
| 13
| 41
| 2.239919
| 0.025096
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,1570,1445,1869,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,766,821,695,741,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,-0.3150370549937861,-0.22797146657486117,-0.5585543448403263,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.3013170110599651,0.25201882658425456,0.3739010819588171,0.3256911134093675,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Membrane lipid catabolic process
| 8
| 11
| 2.232005
| 0.025615
|
Q13510,P04062,O95470,P06865,P50897,P06280,P04066,P07686
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
361,236,269,209,112,339,310,536
|
269,236,310,339,209,536,609,112,361,1115,1723
|
1.0216002256059087,1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,0.5372180454514659,0.44490440798943937,1.807535106013106,0.7991941651751763,0.047126781746465576,-0.4043641190777143
| 2,468
|
Protein processing
| 10
| 38
| 2.231511
| 0.025647
|
O75503,Q10713,O75844,P42892,P67812,Q5JRX3,Q92896,O75976,P50579,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,257,36,39,173,272,94,276,28,61
|
684,1606,66,1412,36,276,1271,2198,1829,1021,1155,2449,597,2035,539,39,28,173,257,1281,1136,61,890,272,1706,2408,314,1665,94,724,1326,1463,1746,1910,1396,1862,1263,2150
|
0.3739010819588171,-0.34455645734238355,2.3395309528321633,-0.1994350717264357,2.868122282262257,1.0020254240102997,-0.08762466761145592,-0.9236044800386676,-0.5271658967301447,0.09954637705818221,-0.006127331605984542,-3.078970856737308,0.4682311897943023,-0.7198459356446938,0.5372180454514659,2.827005651000117,2.928608323075618,1.3365673787376733,1.0603817720347808,-0.08762466761145592,0.020605480698360126,2.4130652487639477,0.20197116058474252,1.0216002256059087,-0.4043641190777143,-1.7863055278776567,0.9224673008330843,-0.3743308591385381,1.9821392383520264,0.34988503514948976,-0.11523365842189977,-0.22797146657486117,-0.4346601796282852,-0.590226648688484,-0.17113556168396907,-0.5271658967301447,-0.06023936284890438,-0.8202718560579666
| 2,468
|
Delayed puberty
| 15
| 47
| 2.23093
| 0.025686
|
Q9Y3E5,P21359,O75844,P40763,Q15042,P63241,O00429,P04062,O00170,Q14108,P06280,P27635,P16435,Q13045,Q8IY37
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
391,415,36,416,233,171,412,236,207,84,339,83,245,248,411
|
207,412,1189,2366,36,1609,236,1526,339,754,245,415,83,1533,2119,416,1382,615,669,1451,171,2305,1030,1209,451,248,1387,84,1583,233,1067,619,1981,800,411,2229,529,828,861,727,1145,1261,1915,1297,1225,1187,391
|
1.2107906833937936,0.692646228876154,-0.033074608598505244,-1.4489724671135231,2.868122282262257,-0.34455645734238355,1.117653769245169,-0.2857688748733796,0.8408260074769911,0.3013170110599651,1.0795911798832665,0.692646228876154,2.119881427808456,-0.2857688748733796,-0.8202718560579666,0.692646228876154,-0.17113556168396907,0.44490440798943937,0.3977415176858454,-0.22797146657486117,1.3541153522401639,-1.214542773220608,0.09954637705818221,-0.033074608598505244,0.6490043765907978,1.0795911798832665,-0.17113556168396907,2.119881427808456,-0.3150370549937861,1.1365094929601929,0.07343946733113242,0.44490440798943937,-0.65444091817572,0.27676037958362715,0.7142445586094798,-0.994181179090294,0.5598892765754294,0.25201882658425456,0.22708991471684983,0.34988503514948976,0.020605480698360126,-0.06023936284890438,-0.590226648688484,-0.08762466761145592,-0.033074608598505244,-0.006127331605984542,0.7570047251940325
| 2,468
|
Phosphatase regulator activity
| 7
| 15
| 2.22762
| 0.025906
|
Q15435,Q86XL3,P30154,P30153,P0DP25,Q15257,Q01105
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
454,35,450,326,608,177,87
|
1150,608,983,326,450,887,738,87,925,177,454,35,1629,648,1224
|
-0.006127331605984542,0.44490440798943937,0.1254502957539166,0.8819129546814536,0.6490043765907978,0.20197116058474252,0.3256911134093675,2.0792599080996506,0.17666003360338126,1.3189165219976549,0.6490043765907978,2.8783012459093062,-0.34455645734238355,0.42140856532916043,-0.033074608598505244
| 2,468
|
Vacuole
| 40
| 164
| 2.223591
| 0.026176
|
Q9UMR5,Q8N511,P42785,Q9UHG3,O14773,P16278,Q9H270,Q9BTY2,P07602,O00584,Q8WTV0,P42892,Q9HC07,Q9H269,Q9Y487,Q15165,P07437,P19474,O95772,Q9UIQ6,P68371,P04066,P50851,O75503,Q9Y2T2,P15586,Q93050,P07858,P10619,P06865,Q14108,P06280,Q8NCC3,Q07065,Q8IV08,P11117,Q99536,P04062,P50897,Q5BJF2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
133,6,8,10,141,18,274,152,31,281,38,39,307,172,181,48,299,50,51,58,312,310,193,66,332,325,76,80,81,209,84,339,88,349,100,229,235,236,112,116
|
2113,835,281,729,1119,141,487,977,2083,504,1637,1793,1442,464,953,1120,431,66,1412,1756,1682,51,2156,1683,446,236,310,1195,339,209,1829,1644,299,31,536,80,732,1965,1481,956,2116,1831,1685,1234,81,229,1445,1302,1484,325,18,609,50,914,2171,984,2059,1380,2030,634,1694,555,815,1534,524,1697,1614,8,39,1161,2123,1579,193,112,819,1205,1836,1934,2392,669,1027,1278,1244,693,1699,2004,1701,735,1702,1740,672,312,497,847,694,1248,1209,820,349,2072,1314,1874,1650,1806,361,84,1213,48,116,2203,100,6,1628,88,1663,2204,38,529,1665,827,76,1002,1430,2299,1857,624,1713,1177,235,1178,501,1910,2330,152,2467,1364,1004,861,863,459,172,274,307,1042,550,628,1916,516,2292,10,1117,58,1472,133,651,2365,531,1917,332,1403,181,1405,1918,654
|
-0.8202718560579666,0.22708991471684983,0.9823261264765617,0.3256911134093675,0.020605480698360126,1.5895402794086952,0.6047569844332618,0.1254502957539166,-0.7864806683003362,0.58240161346863,-0.3743308591385381,-0.4960569056469889,-0.22797146657486117,0.6269572845849924,0.15115395482942545,0.020605480698360126,0.6709000913867084,2.3395309528321633,-0.1994350717264357,-0.46522306940850683,-0.4043641190777143,2.5544363806012425,-0.8543859267849101,-0.4043641190777143,0.6490043765907978,1.117653769245169,0.9224673008330843,-0.033074608598505244,0.8408260074769911,1.2107906833937936,-0.5271658967301447,-0.3743308591385381,0.9425484828699386,2.908601987092757,0.5372180454514659,2.1599235408173723,0.3256911134093675,-0.65444091817572,-0.2567482190180186,0.15115395482942545,-0.8202718560579666,-0.5271658967301447,-0.4043641190777143,-0.06023936284890438,2.1599235408173723,1.1365094929601929,-0.22797146657486117,-0.11523365842189977,-0.2567482190180186,0.8819129546814536,3.1754755052007098,0.44490440798943937,2.5658905492788504,0.17666003360338126,-0.8888282886905626,0.1254502957539166,-0.7530070814189461,-0.17113556168396907,-0.7198459356446938,0.42140856532916043,-0.4043641190777143,0.5143859578494419,0.25201882658425456,-0.2857688748733796,0.5598892765754294,-0.4043641190777143,-0.34455645734238355,3.5056872507526013,2.827005651000117,-0.006127331605984542,-0.8202718560579666,-0.3150370549937861,1.2653360299982175,1.807535106013106,0.25201882658425456,-0.033074608598505244,-0.5271658967301447,-0.6221873063453945,-1.6138737694884546,0.3977415176858454,0.09954637705818221,-0.08762466761145592,-0.06023936284890438,0.3739010819588171,-0.4043641190777143,-0.6869921898793442,-0.4043641190777143,0.3256911134093675,-0.4043641190777143,-0.4346601796282852,0.3977415176858454,0.9224673008330843,0.6047569844332618,0.22708991471684983,0.3739010819588171,-0.06023936284890438,-0.033074608598505244,0.25201882658425456,0.8200789823454424,-0.7530070814189461,-0.11523365842189977,-0.5585543448403263,-0.3743308591385381,-0.4960569056469889,0.7991941651751763,2.119881427808456,-0.033074608598505244,2.5886536324101614,1.7924944732535362,-0.9236044800386676,1.9106764725104468,3.681490447648572,-0.34455645734238355,2.065588110324613,-0.3743308591385381,-0.9236044800386676,2.857903513986415,0.5598892765754294,-0.3743308591385381,0.25201882658425456,2.199400481282764,0.1254502957539166,-0.1994350717264357,-1.1768795353111265,-0.5271658967301447,0.44490440798943937,-0.4043641190777143,-0.006127331605984542,1.1365094929601929,-0.006127331605984542,0.6047569844332618,-0.590226648688484,-1.2910471139088535,1.5075840575864408,-10.399284047667013,-0.1430695347463049,0.1254502957539166,0.22708991471684983,0.22708991471684983,0.6490043765907978,1.3541153522401639,1.0216002256059087,0.9425484828699386,0.09954637705818221,0.5372180454514659,0.44490440798943937,-0.590226648688484,0.58240161346863,-1.139599641176551,3.489782484645634,0.047126781746465576,2.4728673792906726,-0.22797146657486117,1.6376421273678423,0.42140856532916043,-1.4088574939002534,0.5598892765754294,-0.590226648688484,0.8819129546814536,-0.17113556168396907,1.3189165219976549,-0.17113556168396907,-0.590226648688484,0.42140856532916043
| 2,468
|
Process utilizing autophagic mechanism
| 47
| 122
| 2.219816
| 0.026431
|
P21796,O43633,Q96EB6,P38606,Q9Y263,P09601,Q9H270,O15269,P07602,Q9UNH7,O75844,P55061,P40763,Q9Y2S7,P52789,Q9H269,O00429,Q9Y487,P19474,P16615,Q16543,O75436,Q66K74,P50851,P09429,Q9H267,P49841,P30536,Q93050,Q9H6U6,P10619,Q8IYI6,Q00535,Q86Y82,Q08379,Q9NZJ7,Q96GC9,Q99816,Q15042,Q13464,Q9UPT5,P04062,Q8IXJ6,P62820,Q9NZ45,O14964,Q9Y6I9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,504,398,524,145,522,274,153,31,428,36,419,416,569,303,172,412,181,50,434,585,431,587,193,319,459,327,73,76,480,81,211,601,474,471,628,624,365,233,617,502,236,109,359,115,487,654
|
1919,412,487,1407,977,153,1440,504,1229,2086,431,36,1192,837,236,2027,1758,1570,2157,1644,31,732,1153,2116,319,522,81,1445,2210,811,434,1155,50,1303,1833,662,914,2171,4,1198,1380,73,524,416,1614,2035,2124,327,193,1934,669,303,1736,993,419,1699,1737,1702,359,2097,1352,601,847,766,820,471,617,1135,1167,233,2074,585,2178,587,856,1170,1285,1071,474,109,211,2229,1460,76,1002,398,624,701,1667,1713,1986,1178,2288,365,934,1597,459,172,274,727,1396,480,804,2251,1078,1558,115,628,1600,2292,1117,1786,651,428,502,1917,145,569,1403,181,1918,654
|
-0.6221873063453945,0.692646228876154,0.6047569844332618,-0.1994350717264357,0.1254502957539166,1.4909169970454357,-0.22797146657486117,0.58240161346863,-0.06023936284890438,-0.7864806683003362,0.6709000913867084,2.868122282262257,-0.033074608598505244,0.22708991471684983,1.117653769245169,-0.7198459356446938,-0.46522306940850683,-0.3150370549937861,-0.8543859267849101,-0.3743308591385381,2.908601987092757,0.3256911134093675,-0.006127331605984542,-0.8202718560579666,0.9022559500015589,0.5598892765754294,2.1599235408173723,-0.22797146657486117,-0.958720173237647,0.25201882658425456,0.6709000913867084,-0.006127331605984542,2.5658905492788504,-0.11523365842189977,-0.5271658967301447,0.3977415176858454,0.17666003360338126,-0.8888282886905626,3.838410894509741,-0.033074608598505244,-0.17113556168396907,2.238325990048142,0.5598892765754294,0.692646228876154,-0.34455645734238355,-0.7198459356446938,-0.8202718560579666,0.8819129546814536,1.2653360299982175,-0.6221873063453945,0.3977415176858454,0.9425484828699386,-0.4346601796282852,0.1254502957539166,0.692646228876154,-0.4043641190777143,-0.4346601796282852,-0.4043641190777143,0.7991941651751763,-0.7864806683003362,-0.1430695347463049,0.4682311897943023,0.22708991471684983,0.3013170110599651,0.25201882658425456,0.6269572845849924,0.44490440798943937,0.020605480698360126,-0.006127331605984542,1.1365094929601929,-0.7530070814189461,0.49139101679695213,-0.8888282886905626,0.49139101679695213,0.22708991471684983,-0.006127331605984542,-0.08762466761145592,0.07343946733113242,0.6269572845849924,1.8224978231489162,1.2107906833937936,-0.994181179090294,-0.22797146657486117,2.199400481282764,0.1254502957539166,0.7356968204452725,0.44490440798943937,0.3739010819588171,-0.3743308591385381,-0.4043641190777143,-0.65444091817572,-0.006127331605984542,-1.139599641176551,0.7991941651751763,0.17666003360338126,-0.3150370549937861,0.6490043765907978,1.3541153522401639,1.0216002256059087,0.34988503514948976,-0.17113556168396907,0.6269572845849924,0.27676037958362715,-1.0299934512102915,0.07343946733113242,-0.2857688748733796,1.807535106013106,0.44490440798943937,-0.3150370549937861,-1.139599641176551,0.047126781746465576,-0.46522306940850683,0.42140856532916043,0.692646228876154,0.6047569844332618,-0.590226648688484,1.5570300603921419,0.5143859578494419,-0.17113556168396907,1.3189165219976549,-0.590226648688484,0.42140856532916043
| 2,468
|
RNA-binding domain superfamily [IPR035979]
| 57
| 122
| 3.24263
| 0.001184
|
O14979,O43390,P23588,Q01844,Q13247,Q13242,Q9BXP5,Q99729,P31943,P52597,O15047,Q9UN86,Q86V81,Q8IY67,Q15056,P11940,P22626,Q16629,Q13151,Q9Y2U8,Q01085,Q96PK6,Q71RC2,P98175,O75494,P98179,P07910,Q9P2K5,P78332,P52272,O95453,P52756,P19338,P35637,P43243,Q9UHX1,Q9BWF3,Q07955,Q15233,P31942,Q13310,Q92804,P38159,Q15424,Q8NDT2,Q15020,Q14103,P09651,P62995,P55795,Q9Y6M1,O60506,P23246,P51991,Q9P2N5,P08579,Q86U42
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
128,129,259,133,520,263,666,138,137,146,644,284,408,540,406,401,159,428,536,568,297,176,556,310,182,60,315,593,327,454,573,455,575,81,578,345,212,339,472,87,470,90,91,611,482,610,237,604,235,234,385,111,242,244,250,628,254
|
1122,792,128,1443,644,129,695,111,182,829,573,1280,315,628,1832,1357,604,401,864,652,575,159,242,259,1183,1453,2097,87,137,1541,81,91,2135,578,1645,244,454,146,455,234,1239,235,327,871,310,60,297,133,1368,2619,339,909,1294,811,536,263,680,520,1147,470,1091,237,1371,1700,1373,610,406,472,1945,611,2068,1151,428,1374,1245,556,1748,254,408,1162,540,1469,746,482,1659,846,2249,815,2071,90,1753,957,881,176,848,2196,138,2413,212,666,1064,885,723,2319,1575,1625,1479,1214,1393,593,250,1759,345,1999,892,856,284,568,1440,1484,1121,385
|
0.06560596082580177,0.29012025009768083,1.6588740220805571,-0.1398785959133766,0.42524226721919817,1.6588740220805571,0.3716548214149085,1.8585992820751742,1.319881581600934,0.26262791247117023,0.504501785431343,-0.021383766664227755,0.9538838337472978,0.45181010850325676,-0.385979494061243,-0.08026602431198727,0.4782294385308354,0.7594615984524137,0.2349756872773074,0.42524226721919817,0.504501785431343,1.4499668634992937,1.1405038133141903,1.0945486200442405,0.036784554335826614,-0.1398785959133766,-0.5791140239235776,2.087156944238238,1.597201013430558,-0.20023841286057453,2.160827351832918,2.031097928717653,-0.6120605797493264,0.504501785431343,-0.26136298554392196,1.1405038133141903,0.6844163633500198,1.5346812984581808,0.6844163633500198,1.1633112587408174,0.007788633325283703,1.1633112587408174,0.9300199004069388,0.2349756872773074,0.9776259405477873,2.3921856631301304,1.0012473661035215,1.6178517102360863,-0.08026602431198727,-1.516631141683355,0.9060329793006716,0.2071618461975449,-0.021383766664227755,0.29012025009768083,0.5566115286243463,1.0945486200442405,0.39852436325326,0.5824518687603596,0.06560596082580177,0.6591319741805618,0.09425478550483424,1.1633112587408174,-0.08026602431198727,-0.2922176920491657,-0.08026602431198727,0.4782294385308354,0.7594615984524137,0.6591319741805618,-0.449509590099947,0.4782294385308354,-0.5463883460250468,0.06560596082580177,0.7345798472794599,-0.08026602431198727,0.007788633325283703,0.5306286544959777,-0.3232704296671488,1.1175832808973218,0.7594615984524137,0.06560596082580177,0.5566115286243463,-0.1398785959133766,0.3446320422674998,0.6337106835947478,-0.26136298554392196,0.26262791247117023,-0.7122535027473694,0.29012025009768083,-0.5463883460250468,2.049862232695574,-0.3232704296671488,0.1791846335137533,0.2349756872773074,1.363654540627114,0.26262791247117023,-0.6452307866220199,1.5764562446123624,-0.9189941109407576,1.231065281813778,0.42524226721919817,0.12273293000494902,0.2349756872773074,0.3716548214149085,-0.780205401999509,-0.20023841286057453,-0.23070398700916023,-0.1398785959133766,0.036784554335826614,-0.08026602431198727,0.504501785431343,1.1405038133141903,-0.3232704296671488,0.9060329793006716,-0.48158877982782056,0.2349756872773074,0.26262791247117023,1.0481326767167887,0.5306286544959777,-0.1099799759281711,-0.1398785959133766,0.09425478550483424,0.8088316185366753
| 2,702
|
Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]
| 61
| 121
| 3.168082
| 0.001534
|
O14979,O43390,P23588,Q01844,Q13247,Q13242,P31943,Q99729,P52597,O15047,Q9UN86,Q86V81,Q8IY67,Q15056,P18615,P11940,P22626,Q16629,Q13151,Q9Y2U8,Q53F19,Q13243,Q01085,Q96PK6,P98175,O75494,P98179,P07910,Q9BZI7,Q9P2K5,P78332,O43719,P52272,O95453,P52756,P19338,P35637,P43243,Q9UHX1,Q9BWF3,Q07955,Q15233,P31942,Q9H501,Q13310,Q92804,P38159,Q15424,Q8NDT2,Q15020,Q14103,P09651,P62995,P55795,Q9Y6M1,O60506,P23246,P51991,Q9P2N5,P08579,Q86U42
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
128,129,259,133,520,263,137,138,146,644,284,408,540,406,652,401,159,428,536,568,682,680,297,176,310,182,60,315,723,593,327,695,454,573,455,575,81,578,345,212,339,472,87,750,470,90,91,611,482,610,237,604,235,234,385,111,242,244,250,628,254
|
1122,792,128,1443,644,129,695,111,182,829,573,1280,315,628,1832,1357,604,401,864,652,575,159,242,259,1183,1453,2097,87,137,1541,81,91,2135,578,1645,244,454,146,455,234,1239,1187,235,327,871,310,60,297,133,2619,339,909,1294,811,536,263,680,520,1147,470,1091,237,1371,1700,1373,610,406,472,1945,611,2068,1151,2462,428,1374,682,1245,1748,254,408,1162,540,1469,746,482,1659,846,2249,815,2071,90,1753,957,881,176,848,2196,138,212,1064,885,723,2319,750,1625,1479,1214,1393,593,250,1759,345,1999,892,856,284,568,1440,1484,1121,385
|
0.06560596082580177,0.29012025009768083,1.6588740220805571,-0.1398785959133766,0.42524226721919817,1.6588740220805571,0.3716548214149085,1.8585992820751742,1.319881581600934,0.26262791247117023,0.504501785431343,-0.021383766664227755,0.9538838337472978,0.45181010850325676,-0.385979494061243,-0.08026602431198727,0.4782294385308354,0.7594615984524137,0.2349756872773074,0.42524226721919817,0.504501785431343,1.4499668634992937,1.1405038133141903,1.0945486200442405,0.036784554335826614,-0.1398785959133766,-0.5791140239235776,2.087156944238238,1.597201013430558,-0.20023841286057453,2.160827351832918,2.031097928717653,-0.6120605797493264,0.504501785431343,-0.26136298554392196,1.1405038133141903,0.6844163633500198,1.5346812984581808,0.6844163633500198,1.1633112587408174,0.007788633325283703,0.036784554335826614,1.1633112587408174,0.9300199004069388,0.2349756872773074,0.9776259405477873,2.3921856631301304,1.0012473661035215,1.6178517102360863,-1.516631141683355,0.9060329793006716,0.2071618461975449,-0.021383766664227755,0.29012025009768083,0.5566115286243463,1.0945486200442405,0.39852436325326,0.5824518687603596,0.06560596082580177,0.6591319741805618,0.09425478550483424,1.1633112587408174,-0.08026602431198727,-0.2922176920491657,-0.08026602431198727,0.4782294385308354,0.7594615984524137,0.6591319741805618,-0.449509590099947,0.4782294385308354,-0.5463883460250468,0.06560596082580177,-1.0257109093739025,0.7345798472794599,-0.08026602431198727,0.39852436325326,0.007788633325283703,-0.3232704296671488,1.1175832808973218,0.7594615984524137,0.06560596082580177,0.5566115286243463,-0.1398785959133766,0.3446320422674998,0.6337106835947478,-0.26136298554392196,0.26262791247117023,-0.7122535027473694,0.29012025009768083,-0.5463883460250468,2.049862232695574,-0.3232704296671488,0.1791846335137533,0.2349756872773074,1.363654540627114,0.26262791247117023,-0.6452307866220199,1.5764562446123624,1.231065281813778,0.12273293000494902,0.2349756872773074,0.3716548214149085,-0.780205401999509,0.3446320422674998,-0.23070398700916023,-0.1398785959133766,0.036784554335826614,-0.08026602431198727,0.504501785431343,1.1405038133141903,-0.3232704296671488,0.9060329793006716,-0.48158877982782056,0.2349756872773074,0.26262791247117023,1.0481326767167887,0.5306286544959777,-0.1099799759281711,-0.1398785959133766,0.09425478550483424,0.8088316185366753
| 2,702
|
Negative regulation of mrna catabolic process
| 10
| 22
| 3.167792
| 0.001536
|
P07910,Q9Y2W1,P16989,Q99729,Q14103,O60506,P35637,P98175,P67809,Q92804
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
315,396,72,138,237,111,81,310,121,90
|
111,796,315,401,72,81,121,310,1088,910,811,536,237,1151,913,990,2071,90,138,724,1393,396
|
1.8585992820751742,0.29012025009768083,0.9538838337472978,0.7594615984524137,2.2691039308231553,2.160827351832918,1.7197212915351867,0.9776259405477873,0.09425478550483424,0.2071618461975449,0.29012025009768083,0.5566115286243463,1.1633112587408174,0.06560596082580177,0.2071618461975449,0.15104226553426064,-0.5463883460250468,2.049862232695574,1.5764562446123624,0.3716548214149085,-0.08026602431198727,0.784211761763469
| 2,702
|
Negative regulation of mrna metabolic process
| 18
| 43
| 3.083134
| 0.002048
|
P07910,P67809,Q9Y2W1,Q13242,P16989,Q99729,P50750,Q14103,O60506,P35637,P98175,Q5VTR2,O75494,P61978,Q92804,P38159,P11940,P22626
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
315,121,396,263,72,138,389,237,111,81,310,211,182,153,90,91,401,159
|
1401,2230,111,549,182,796,315,401,72,652,159,1183,1453,81,91,389,153,121,310,1088,1242,909,910,1988,811,536,263,520,237,1945,1151,913,428,211,841,1558,990,2071,90,138,724,1393,396
|
-0.1099799759281711,-0.7122535027473694,1.8585992820751742,0.5306286544959777,1.319881581600934,0.29012025009768083,0.9538838337472978,0.7594615984524137,2.2691039308231553,0.42524226721919817,1.4499668634992937,0.036784554335826614,-0.1398785959133766,2.160827351832918,2.031097928717653,0.784211761763469,1.4925203872541544,1.7197212915351867,0.9776259405477873,0.09425478550483424,0.007788633325283703,0.2071618461975449,0.2071618461975449,-0.48158877982782056,0.29012025009768083,0.5566115286243463,1.0945486200442405,0.5824518687603596,1.1633112587408174,-0.449509590099947,0.06560596082580177,0.2071618461975449,0.7345798472794599,1.231065281813778,0.26262791247117023,-0.20023841286057453,0.15104226553426064,-0.5463883460250468,2.049862232695574,1.5764562446123624,0.3716548214149085,-0.08026602431198727,0.784211761763469
| 2,702
|
RNA recognition motif domain [IPR000504]
| 54
| 110
| 3.079777
| 0.002072
|
O14979,O43390,P23588,Q01844,Q13247,Q13242,P31943,Q99729,P52597,O15047,Q9UN86,Q86V81,Q8IY67,Q15056,P18615,P11940,P22626,Q16629,Q13151,Q01085,Q96PK6,P98175,O75494,P98179,P07910,Q9P2K5,P78332,P52272,P52756,P19338,P35637,P43243,Q9UHX1,Q9BWF3,Q07955,Q15233,P31942,Q13310,Q92804,P38159,Q15424,Q8NDT2,Q15020,Q14103,P09651,P62995,P55795,Q9Y6M1,O60506,P23246,P51991,Q9P2N5,P08579,Q86U42
|
Sequence
|
InterPro Domain
|
interpro_domain
|
128,129,259,133,520,263,137,138,146,644,284,408,540,406,652,401,159,428,536,297,176,310,182,60,315,593,327,454,455,575,81,578,345,212,339,472,87,470,90,91,611,482,610,237,604,235,234,385,111,242,244,250,628,254
|
1122,792,128,1443,644,129,695,111,182,829,1280,315,628,1832,1357,604,401,864,652,575,159,242,259,1183,1453,2097,87,137,1541,81,91,2135,578,1645,244,454,146,455,234,1239,235,327,871,310,60,297,133,2619,339,909,1294,811,536,263,680,520,1147,470,1091,237,1371,1700,1373,610,406,472,1945,611,2068,1151,428,1374,1245,1748,254,408,1162,540,1469,746,482,846,2249,815,90,1753,957,881,176,848,2196,138,212,1064,885,2319,1625,1479,1214,1393,593,250,345,1999,892,284,1440,1484,1121,385
|
0.06560596082580177,0.29012025009768083,1.6588740220805571,-0.1398785959133766,0.42524226721919817,1.6588740220805571,0.3716548214149085,1.8585992820751742,1.319881581600934,0.26262791247117023,-0.021383766664227755,0.9538838337472978,0.45181010850325676,-0.385979494061243,-0.08026602431198727,0.4782294385308354,0.7594615984524137,0.2349756872773074,0.42524226721919817,0.504501785431343,1.4499668634992937,1.1405038133141903,1.0945486200442405,0.036784554335826614,-0.1398785959133766,-0.5791140239235776,2.087156944238238,1.597201013430558,-0.20023841286057453,2.160827351832918,2.031097928717653,-0.6120605797493264,0.504501785431343,-0.26136298554392196,1.1405038133141903,0.6844163633500198,1.5346812984581808,0.6844163633500198,1.1633112587408174,0.007788633325283703,1.1633112587408174,0.9300199004069388,0.2349756872773074,0.9776259405477873,2.3921856631301304,1.0012473661035215,1.6178517102360863,-1.516631141683355,0.9060329793006716,0.2071618461975449,-0.021383766664227755,0.29012025009768083,0.5566115286243463,1.0945486200442405,0.39852436325326,0.5824518687603596,0.06560596082580177,0.6591319741805618,0.09425478550483424,1.1633112587408174,-0.08026602431198727,-0.2922176920491657,-0.08026602431198727,0.4782294385308354,0.7594615984524137,0.6591319741805618,-0.449509590099947,0.4782294385308354,-0.5463883460250468,0.06560596082580177,0.7345798472794599,-0.08026602431198727,0.007788633325283703,-0.3232704296671488,1.1175832808973218,0.7594615984524137,0.06560596082580177,0.5566115286243463,-0.1398785959133766,0.3446320422674998,0.6337106835947478,0.26262791247117023,-0.7122535027473694,0.29012025009768083,2.049862232695574,-0.3232704296671488,0.1791846335137533,0.2349756872773074,1.363654540627114,0.26262791247117023,-0.6452307866220199,1.5764562446123624,1.231065281813778,0.12273293000494902,0.2349756872773074,-0.780205401999509,-0.23070398700916023,-0.1398785959133766,0.036784554335826614,-0.08026602431198727,0.504501785431343,1.1405038133141903,0.9060329793006716,-0.48158877982782056,0.2349756872773074,1.0481326767167887,-0.1099799759281711,-0.1398785959133766,0.09425478550483424,0.8088316185366753
| 2,702
|
Proto-oncogene
| 14
| 36
| 3.010699
| 0.002606
|
Q16204,P35658,Q9BZ95,Q01844,Q92804,Q92734,Q01105,O96028,P35637,P06753,P31749,Q9H6U6,Q92733,Q03164
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
197,3,164,133,90,301,169,75,81,229,145,189,219,62
|
650,75,702,229,1492,1131,293,2267,145,2360,81,3,2172,1362,1184,2013,868,1982,169,133,62,367,1851,1744,1511,197,219,301,90,2663,848,1001,2198,164,1620,189
|
0.42524226721919817,2.233303018813176,0.3716548214149085,1.1633112587408174,-0.1699640181909275,0.06560596082580177,1.0012473661035215,-0.7461118187735932,1.5346812984581808,-0.8491105936663824,2.160827351832918,4.779930332154013,-0.6452307866220199,-0.08026602431198727,0.036784554335826614,-0.5138808228281478,0.2349756872773074,-0.48158877982782056,1.3853854720918395,1.6178517102360863,2.374810019413564,0.8333224319696179,-0.385979494061243,-0.3232704296671488,-0.1699640181909275,1.2756876781734239,1.208590985594112,1.0012473661035215,2.049862232695574,-1.9731578815729123,0.26262791247117023,0.15104226553426064,-0.6452307866220199,1.4285407486745718,-0.23070398700916023,1.2978377151319078
| 2,702
|
Regulation of mrna metabolic process
| 55
| 137
| 2.996881
| 0.002728
|
Q13464,Q13247,Q13242,Q9Y2W1,Q92945,Q99729,P50750,Q07666,P31749,Q8IY67,P61978,Q13868,Q969T7,P51114,P22626,P11940,Q16629,Q5JVF3,Q13151,Q6Y7W6,Q96MU7,P08670,P17844,P98175,O75494,O75150,Q9NZN8,Q9NQT5,P98179,P07910,Q9P2K5,Q9HCE1,P51116,P16989,P52272,O95453,P52756,P19338,P35637,Q9UHX1,Q9BWF3,Q5VTR2,Q6P6C2,Q13310,Q92804,P38159,O43865,Q15424,P51003,Q8NDT2,Q14103,P09651,P62995,O60506,P67809
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
521,520,263,396,265,138,389,270,145,540,153,279,158,289,159,401,428,163,536,299,560,49,417,310,182,549,449,59,60,315,593,199,196,72,454,573,455,575,81,345,212,211,613,470,90,91,464,611,224,482,237,604,235,111,121
|
1581,2679,1401,2230,1676,2163,464,111,549,182,796,573,702,315,1832,49,1357,604,1231,401,864,72,417,1685,652,575,159,1183,1453,2134,2095,2097,145,81,91,1497,1645,389,224,289,196,1936,454,455,2062,1546,153,2460,235,121,2404,871,310,60,1088,873,1242,270,909,910,1508,1988,811,536,263,520,470,521,1046,1091,279,237,1371,1700,984,1945,611,2068,1853,1151,913,428,1374,1855,163,211,1246,1467,2282,613,841,1558,990,299,916,1158,2314,540,2533,746,1658,1163,482,2365,2071,90,638,1753,921,265,158,1662,1708,957,560,1519,1664,848,138,212,2288,724,1919,1816,199,888,59,2202,1393,449,593,345,2156,1528,2122,396,1121
|
-0.23070398700916023,-2.3797721160822345,-0.1099799759281711,-0.7122535027473694,-0.2922176920491657,-0.6452307866220199,0.6591319741805618,1.8585992820751742,0.5306286544959777,1.319881581600934,0.29012025009768083,0.504501785431343,0.3716548214149085,0.9538838337472978,-0.385979494061243,2.511943158877311,-0.08026602431198727,0.4782294385308354,0.007788633325283703,0.7594615984524137,0.2349756872773074,2.2691039308231553,0.7345798472794599,-0.2922176920491657,0.42524226721919817,0.504501785431343,1.4499668634992937,0.036784554335826614,-0.1398785959133766,-0.6120605797493264,-0.5791140239235776,-0.5791140239235776,1.5346812984581808,2.160827351832918,2.031097928717653,-0.1699640181909275,-0.26136298554392196,0.784211761763469,1.1860066448125965,1.0247492400647817,1.2756876781734239,-0.449509590099947,0.6844163633500198,0.6844163633500198,-0.5463883460250468,-0.20023841286057453,1.4925203872541544,-1.0257109093739025,1.1633112587408174,1.7197212915351867,-0.9189941109407576,0.2349756872773074,0.9776259405477873,2.3921856631301304,0.09425478550483424,0.2349756872773074,0.007788633325283703,1.0713987752533087,0.2071618461975449,0.2071618461975449,-0.1699640181909275,-0.48158877982782056,0.29012025009768083,0.5566115286243463,1.0945486200442405,0.5824518687603596,0.6591319741805618,0.5824518687603596,0.12273293000494902,0.09425478550483424,1.0481326767167887,1.1633112587408174,-0.08026602431198727,-0.2922176920491657,0.15104226553426064,-0.449509590099947,0.4782294385308354,-0.5463883460250468,-0.385979494061243,0.06560596082580177,0.2071618461975449,0.7345798472794599,-0.08026602431198727,-0.385979494061243,1.4285407486745718,1.231065281813778,0.007788633325283703,-0.1398785959133766,-0.7461118187735932,0.4782294385308354,0.26262791247117023,-0.20023841286057453,0.15104226553426064,1.0012473661035215,0.2071618461975449,0.06560596082580177,-0.780205401999509,0.5566115286243463,-1.1716755310485276,0.3446320422674998,-0.26136298554392196,0.06560596082580177,0.6337106835947478,-0.8491105936663824,-0.5463883460250468,2.049862232695574,0.45181010850325676,-0.3232704296671488,0.2071618461975449,1.0945486200442405,1.4712931239277853,-0.26136298554392196,-0.2922176920491657,0.1791846335137533,0.5306286544959777,-0.1699640181909275,-0.26136298554392196,0.26262791247117023,1.5764562446123624,1.231065281813778,-0.7461118187735932,0.3716548214149085,-0.4176406731946431,-0.35452356200396523,1.2756876781734239,0.2349756872773074,2.4094934860042883,-0.6452307866220199,-0.08026602431198727,0.7095652084505555,0.504501785431343,0.9060329793006716,-0.6120605797493264,-0.1699640181909275,-0.5791140239235776,0.784211761763469,0.09425478550483424
| 2,702
|
Intermediate filaments
| 9
| 31
| 2.967885
| 0.002999
|
Q96K76,P48681,Q99471,P08670,Q16352,P07197,Q3SXM5,O75718,P07196
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
110,233,144,49,148,230,340,307,185
|
1226,307,649,1449,730,1277,185,230,49,233,1038,1457,1502,1050,371,148,2145,340,1199,952,686,1165,110,144,1002,2036,1525,1213,1217,934,2294
|
0.007788633325283703,0.9776259405477873,0.42524226721919817,-0.1398785959133766,0.3446320422674998,-0.021383766664227755,1.2978377151319078,1.1633112587408174,2.511943158877311,1.1633112587408174,0.12273293000494902,-0.1398785959133766,-0.1699640181909275,0.12273293000494902,0.8333224319696179,1.5346812984581808,-0.6120605797493264,0.9060329793006716,0.036784554335826614,0.1791846335137533,0.39852436325326,0.06560596082580177,1.8780952360684287,1.5556166081262797,0.15104226553426064,-0.5138808228281478,-0.1699640181909275,0.036784554335826614,0.036784554335826614,0.2071618461975449,-0.7461118187735932
| 2,702
|
Peptidyl proline modification
| 11
| 27
| 2.944598
| 0.003234
|
P49792,P13674,Q9BV86,P26885,Q9NWM8,Q02790,Q96AY3,O15460,P62942,Q32P28,O75718
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
288,34,37,166,135,269,51,55,154,27,307
|
896,55,1924,307,1320,34,2602,166,2443,2096,288,154,837,269,1461,583,2184,1298,2481,27,846,51,819,37,135,1173,359
|
0.2071618461975449,2.4094934860042883,-0.449509590099947,0.9776259405477873,-0.05073464252917762,2.8528380007812295,-1.4378918990793144,1.407013911282315,-0.9898819580382101,-0.5791140239235776,1.0247492400647817,1.4925203872541544,0.26262791247117023,1.0713987752533087,-0.1398785959133766,0.504501785431343,-0.6452307866220199,-0.021383766664227755,-1.0618011603301436,3.2836590722958277,0.26262791247117023,2.4950321897803915,0.29012025009768083,2.7421234593968506,1.6178517102360863,0.06560596082580177,0.8576854474690445
| 2,702
|
Rna stabilization
| 11
| 26
| 2.901914
| 0.003709
|
P07910,Q9Y2W1,Q9H814,P16989,Q14103,O60506,P35637,P98175,P67809,Q92804,P11940
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
315,396,394,72,237,111,81,310,121,90,401
|
111,2002,796,573,315,401,72,81,121,310,1088,910,424,811,536,237,1151,913,990,2071,90,724,1919,394,1393,396
|
1.8585992820751742,-0.5138808228281478,0.29012025009768083,0.504501785431343,0.9538838337472978,0.7594615984524137,2.2691039308231553,2.160827351832918,1.7197212915351867,0.9776259405477873,0.09425478550483424,0.2071618461975449,0.7345798472794599,0.29012025009768083,0.5566115286243463,1.1633112587408174,0.06560596082580177,0.2071618461975449,0.15104226553426064,-0.5463883460250468,2.049862232695574,0.3716548214149085,-0.4176406731946431,0.784211761763469,-0.08026602431198727,0.784211761763469
| 2,702
|
Negative regulation of rna catabolic process
| 12
| 29
| 2.862352
| 0.004205
|
P07910,Q9Y2W1,Q9H814,P16989,Q99729,Q14103,O60506,P35637,P98175,P67809,Q92804,P11940
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
315,396,394,72,138,237,111,81,310,121,90,401
|
111,2002,796,573,315,401,72,81,1934,121,310,1088,910,424,811,536,237,1151,913,990,2071,90,138,2319,724,1919,394,1393,396
|
1.8585992820751742,-0.5138808228281478,0.29012025009768083,0.504501785431343,0.9538838337472978,0.7594615984524137,2.2691039308231553,2.160827351832918,-0.449509590099947,1.7197212915351867,0.9776259405477873,0.09425478550483424,0.2071618461975449,0.7345798472794599,0.29012025009768083,0.5566115286243463,1.1633112587408174,0.06560596082580177,0.2071618461975449,0.15104226553426064,-0.5463883460250468,2.049862232695574,1.5764562446123624,-0.780205401999509,0.3716548214149085,-0.4176406731946431,0.784211761763469,-0.08026602431198727,0.784211761763469
| 2,702
|
Transmembrane receptor protein serine threonine kinase signaling pathway
| 13
| 35
| 2.84995
| 0.004373
|
Q8WUH2,Q92896,Q01082,P62942,Q8N0X7,P09874,Q96PK6,Q8N1F7,P17844,P08670,Q14980,Q9UIQ6,P04637
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
433,393,535,154,167,14,176,541,417,49,537,191,529
|
1219,827,529,1773,1077,49,14,417,653,1084,977,737,154,767,535,1046,1298,537,1514,913,1376,167,541,433,393,1387,1663,176,1667,191,1439,857,858,568,1630
|
0.007788633325283703,0.26262791247117023,0.5566115286243463,-0.35452356200396523,0.09425478550483424,2.511943158877311,3.9740289947398435,0.7345798472794599,0.42524226721919817,0.09425478550483424,0.15104226553426064,0.3446320422674998,1.4925203872541544,0.31745440163525057,0.5566115286243463,0.12273293000494902,-0.021383766664227755,0.5566115286243463,-0.1699640181909275,0.2071618461975449,-0.08026602431198727,1.407013911282315,0.5566115286243463,0.7345798472794599,0.784211761763469,-0.08026602431198727,-0.26136298554392196,1.363654540627114,-0.26136298554392196,1.2978377151319078,-0.1099799759281711,0.26262791247117023,0.26262791247117023,0.5306286544959777,-0.23070398700916023
| 2,702
|
Intermediate filament protein, conserved site [IPR018039]
| 7
| 8
| 2.70772
| 0.006775
|
P48681,P07197,P08670,Q16352,P02545,Q03252,P07196
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
233,230,49,148,178,338,185
|
178,185,230,49,418,233,338,148
|
1.341820214976906,1.2978377151319078,1.1633112587408174,2.511943158877311,0.7345798472794599,1.1633112587408174,0.9060329793006716,1.5346812984581808
| 2,702
|
Intermediate filament, rod domain [IPR039008]
| 7
| 8
| 2.70772
| 0.006775
|
P48681,P07197,P08670,Q16352,P02545,Q03252,P07196
|
Sequence
|
InterPro Domain
|
interpro_domain
|
233,230,49,148,178,338,185
|
178,185,230,49,418,233,338,148
|
1.341820214976906,1.2978377151319078,1.1633112587408174,2.511943158877311,0.7345798472794599,1.1633112587408174,0.9060329793006716,1.5346812984581808
| 2,702
|
Skeletal muscle organ development
| 10
| 19
| 2.696422
| 0.007009
|
P41440,P16989,P50402,Q7Z406,Q15149,P61201,P17844,Q9BYT8,P80723,P51114
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
67,72,295,173,371,608,417,543,469,289
|
2128,1227,72,417,1359,1234,67,295,289,1547,608,469,371,913,173,638,543,1527,935
|
-0.6120605797493264,0.007788633325283703,2.2691039308231553,0.7345798472794599,-0.08026602431198727,0.007788633325283703,2.339853291567594,1.0012473661035215,1.0247492400647817,-0.20023841286057453,0.4782294385308354,0.6591319741805618,0.8333224319696179,0.2071618461975449,1.363654540627114,0.45181010850325676,0.5566115286243463,-0.1699640181909275,0.2071618461975449
| 2,702
|
Nucleophile aminohydrolases, N-terminal [IPR029055]
| 6
| 18
| 2.690043
| 0.007144
|
P49721,Q06203,P28070,P20618,Q99436,P28074
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
68,236,10,231,143,58
|
1402,1450,231,1838,1182,629,1134,1887,10,253,58,1890,68,391,236,2016,2449,143
|
-0.1099799759281711,-0.1398785959133766,1.1633112587408174,-0.385979494061243,0.036784554335826614,0.45181010850325676,0.06560596082580177,-0.4176406731946431,4.127425604581578,1.1175832808973218,2.4094934860042883,-0.4176406731946431,2.339853291567594,0.784211761763469,1.1633112587408174,-0.5138808228281478,-0.9898819580382101,1.5556166081262797
| 2,702
|
Intermediate filament cytoskeleton
| 14
| 31
| 2.626176
| 0.008635
|
P15924,Q9UNZ2,P48681,Q15149,Q99471,P08670,Q16352,P07197,P02545,Q3SXM5,Q03252,Q9H6U6,P14923,P07196
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
326,275,233,371,144,49,148,230,178,340,338,189,402,185
|
1961,649,178,185,230,49,402,326,418,233,1599,1038,1847,1502,2672,338,1554,371,148,2145,340,1199,686,144,1112,189,1525,1213,275,596,2294
|
-0.48158877982782056,0.42524226721919817,1.341820214976906,1.2978377151319078,1.1633112587408174,2.511943158877311,0.7594615984524137,0.9300199004069388,0.7345798472794599,1.1633112587408174,-0.23070398700916023,0.12273293000494902,-0.385979494061243,-0.1699640181909275,-2.149901662757291,0.9060329793006716,-0.20023841286057453,0.8333224319696179,1.5346812984581808,-0.6120605797493264,0.9060329793006716,0.036784554335826614,0.39852436325326,1.5556166081262797,0.09425478550483424,1.2978377151319078,-0.1699640181909275,0.036784554335826614,1.0713987752533087,0.504501785431343,-0.7461118187735932
| 2,702
|
Muscle organ development
| 16
| 33
| 2.6187
| 0.008827
|
P09493,P41440,Q13642,P16989,P15924,P50402,Q7Z406,Q15149,P61201,P17844,Q9BYT8,P80723,P49454,P62942,P30626,P51114
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,67,609,72,326,295,173,371,608,417,543,469,364,154,532,289
|
2128,1227,130,326,72,417,1359,532,1234,67,834,364,295,289,1787,1547,608,154,469,609,876,371,1092,913,173,1911,638,543,726,752,2321,1527,935
|
-0.6120605797493264,0.007788633325283703,1.6588740220805571,0.9300199004069388,2.2691039308231553,0.7345798472794599,-0.08026602431198727,0.5566115286243463,0.007788633325283703,2.339853291567594,0.26262791247117023,0.8333224319696179,1.0012473661035215,1.0247492400647817,-0.35452356200396523,-0.20023841286057453,0.4782294385308354,1.4925203872541544,0.6591319741805618,0.4782294385308354,0.2349756872773074,0.8333224319696179,0.09425478550483424,0.2071618461975449,1.363654540627114,-0.4176406731946431,0.45181010850325676,0.5566115286243463,0.3716548214149085,0.3446320422674998,-0.780205401999509,-0.1699640181909275,0.2071618461975449
| 2,702
|
Micromelia
| 8
| 21
| 2.60854
| 0.009093
|
Q7Z4L5,Q9UQE7,Q9UHX1,Q96HY6,Q15392,O75874,O75718,P48735
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
105,376,345,312,117,54,307,24
|
968,2207,647,2128,307,54,1733,24,1364,1896,1148,457,117,915,105,1561,312,1758,345,376,1723
|
0.15104226553426064,-0.6786274687643568,0.42524226721919817,-0.6120605797493264,0.9776259405477873,2.4267339760166293,-0.3232704296671488,3.3953101294729233,-0.08026602431198727,-0.4176406731946431,0.06560596082580177,0.6844163633500198,1.7996013420160522,0.2071618461975449,1.9168361544314048,-0.20023841286057453,0.9776259405477873,-0.3232704296671488,0.9060329793006716,0.8333224319696179,-0.2922176920491657
| 2,702
|
Calcium-binding protein
| 7
| 14
| 2.552981
| 0.010681
|
Q14257,P80303,Q9Y376,O43852,Q02818,Q8N163,P43307
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
66,262,168,108,119,431,363
|
108,2054,1841,363,1547,764,262,119,66,427,1053,431,960,168
|
1.8780952360684287,-0.5463883460250468,-0.385979494061243,0.8333224319696179,-0.20023841286057453,0.31745440163525057,1.0945486200442405,1.7598374077792183,2.3573660616958487,0.7345798472794599,0.12273293000494902,0.7345798472794599,0.1791846335137533,1.407013911282315
| 2,702
|
Regulation of alternative mrna splicing via spliceosome
| 16
| 29
| 2.512134
| 0.012
|
Q8NDT2,Q9Y2W1,Q13247,P51116,P09651,P62995,Q96MU7,P52756,Q07666,P17844,Q9UHX1,P98175,Q9BWF3,Q8IY67,P38159,P51114
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
482,396,520,196,604,235,560,455,270,417,345,310,212,540,91,289
|
2230,604,864,417,1453,2097,91,1645,289,196,1936,455,235,310,1088,270,520,1945,1855,540,482,638,1753,560,848,212,345,396,1121
|
-0.7122535027473694,0.4782294385308354,0.2349756872773074,0.7345798472794599,-0.1398785959133766,-0.5791140239235776,2.031097928717653,-0.26136298554392196,1.0247492400647817,1.2756876781734239,-0.449509590099947,0.6844163633500198,1.1633112587408174,0.9776259405477873,0.09425478550483424,1.0713987752533087,0.5824518687603596,-0.449509590099947,-0.385979494061243,0.5566115286243463,0.6337106835947478,0.45181010850325676,-0.3232704296671488,0.5306286544959777,0.26262791247117023,1.231065281813778,0.9060329793006716,0.784211761763469,0.09425478550483424
| 2,702
|
Sumoylation of rna binding proteins
| 16
| 30
| 2.490081
| 0.012771
|
P07910,P49792,Q8NFH4,P35658,O75694,Q9BVL2,P12270,Q8N1F7,Q9BTX1,P55735,Q99567,Q8WUM0,P61978,Q99496,Q12769,Q7Z3B4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
315,288,226,3,599,504,293,541,542,738,639,777,153,782,495,685
|
599,315,293,3,1235,1456,288,1546,738,905,153,1606,495,914,685,541,226,1659,1385,777,779,1306,782,639,542,504,926,2078,1481,2326
|
0.4782294385308354,0.9538838337472978,1.0012473661035215,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,-0.20023841286057453,0.3446320422674998,0.2071618461975449,1.4925203872541544,-0.23070398700916023,0.6081511143176388,0.2071618461975449,0.39852436325326,0.5566115286243463,1.1860066448125965,-0.26136298554392196,-0.08026602431198727,0.31745440163525057,0.31745440163525057,-0.021383766664227755,0.31745440163525057,0.45181010850325676,0.5566115286243463,0.6081511143176388,0.2071618461975449,-0.5463883460250468,-0.1398785959133766,-0.780205401999509
| 2,702
|
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