term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Organic acid transmembrane transport
| 7
| 28
| 3.208561
| 0.001334
|
P08183,O43772,P53985,P33527,Q9H2D1,P23786,Q9Y619
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,37,40,75,14,26,125
|
37,1054,1411,2056,1121,1963,32,1481,491,26,1490,1835,75,2066,40,1803,1655,1544,1715,1778,14,1366,1433,1633,199,1297,518,125
|
2.857903513986415,0.07343946733113242,-0.1994350717264357,-0.7530070814189461,0.020605480698360126,-0.65444091817572,2.908601987092757,-0.2567482190180186,0.6047569844332618,2.9583317443973955,-0.2567482190180186,-0.5271658967301447,2.199400481282764,-0.7530070814189461,2.827005651000117,-0.4960569056469889,-0.3743308591385381,-0.2857688748733796,-0.4043641190777143,-0.46522306940850683,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,1.2472629393969026,-0.08762466761145592,0.58240161346863,1.6692773995529553
| 2,468
|
Regulation of ph
| 8
| 20
| 3.172229
| 0.001513
|
O75503,Q8N511,Q93050,Q9Y487,Q92544,P50897,Q15904,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,6,76,181,242,112,284,187
|
66,1412,187,1480,537,1198,634,112,1934,1702,1313,284,6,242,76,1002,307,903,1117,181
|
2.3395309528321633,-0.1994350717264357,1.2833019254548965,-0.2567482190180186,0.5372180454514659,-0.033074608598505244,0.42140856532916043,1.807535106013106,-0.6221873063453945,-0.4043641190777143,-0.11523365842189977,0.9823261264765617,3.681490447648572,1.0986814186639104,2.199400481282764,0.1254502957539166,0.9425484828699386,0.20197116058474252,0.047126781746465576,1.3189165219976549
| 2,468
|
Regulation of cellular ph
| 8
| 20
| 3.172229
| 0.001513
|
O75503,Q8N511,Q93050,Q9Y487,Q92544,P50897,Q15904,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,6,76,181,242,112,284,187
|
66,1412,187,1480,537,1198,634,112,1934,1702,1313,284,6,242,76,1002,307,903,1117,181
|
2.3395309528321633,-0.1994350717264357,1.2833019254548965,-0.2567482190180186,0.5372180454514659,-0.033074608598505244,0.42140856532916043,1.807535106013106,-0.6221873063453945,-0.4043641190777143,-0.11523365842189977,0.9823261264765617,3.681490447648572,1.0986814186639104,2.199400481282764,0.1254502957539166,0.9425484828699386,0.20197116058474252,0.047126781746465576,1.3189165219976549
| 2,468
|
Transport of small molecules
| 46
| 137
| 3.145857
| 0.001656
|
Q8TB61,Q70HW3,P21796,Q10713,O00231,P45880,P35610,P38606,P40855,P09601,Q9UL46,Q9Y277,P23634,P60900,Q8N4V1,P30519,Q15904,P08183,Q99436,Q8WTV0,P53985,Q9HD20,Q9Y487,P61289,P49721,P16615,P28074,P02786,P04920,Q9UBX3,Q93050,P33527,P20618,P10644,Q99808,Q9BPX6,P35613,Q9C0H2,P63208,P28070,P49720,Q15008,P05198,P11166,P28072,Q9Y289
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,3,4,257,251,7,255,524,396,522,147,275,394,408,286,27,284,32,164,38,40,47,181,436,56,434,54,432,187,199,76,75,202,448,342,217,214,89,470,225,230,499,490,491,373,518
|
251,1266,2221,1226,977,533,1728,1606,1961,1640,1337,1682,1300,2156,432,187,981,1642,2157,490,1086,32,1481,1831,522,448,491,811,1612,839,434,1155,756,1690,814,202,914,2171,1691,4,394,1059,1532,1158,1305,2059,1199,225,373,54,1490,27,1966,75,2326,255,1345,214,666,1872,636,524,396,1240,7,1093,230,56,557,2392,1278,40,2283,1245,994,1699,408,436,1702,845,1279,884,1740,470,1903,2008,1100,847,821,257,1281,695,2269,2215,499,1544,284,1507,1141,3,1172,286,965,2181,128,38,1710,76,2299,1746,164,1177,2288,342,217,1594,1717,89,863,1366,1396,1433,47,1010,681,199,551,1080,1117,1263,147,1265,944,275,518,181,2150
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.1254502957539166,0.5372180454514659,-0.4346601796282852,-0.34455645734238355,-0.65444091817572,-0.3743308591385381,-0.1430695347463049,-0.4043641190777143,-0.11523365842189977,-0.8543859267849101,0.6709000913867084,1.2833019254548965,0.1254502957539166,-0.3743308591385381,-0.8543859267849101,0.6047569844332618,0.047126781746465576,2.908601987092757,-0.2567482190180186,-0.5271658967301447,0.5598892765754294,0.6490043765907978,0.6047569844332618,0.25201882658425456,-0.34455645734238355,0.22708991471684983,0.6709000913867084,-0.006127331605984542,0.3013170110599651,-0.4043641190777143,0.25201882658425456,1.2290815354843998,0.17666003360338126,-0.8888282886905626,-0.4043641190777143,3.838410894509741,0.7356968204452725,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.7530070814189461,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.2567482190180186,2.928608323075618,-0.65444091817572,2.199400481282764,-1.2910471139088535,1.0603817720347808,-0.1430695347463049,1.192389231232484,0.3977415176858454,-0.5585543448403263,0.42140856532916043,0.5598892765754294,0.7356968204452725,-0.06023936284890438,3.6667004853346468,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,-1.6138737694884546,-0.08762466761145592,2.827005651000117,-1.139599641176551,-0.06023936284890438,0.1254502957539166,-0.4043641190777143,0.7142445586094798,0.6709000913867084,-0.4043641190777143,0.22708991471684983,-0.08762466761145592,0.20197116058474252,-0.4346601796282852,0.6269572845849924,-0.590226648688484,-0.6869921898793442,0.047126781746465576,0.22708991471684983,0.25201882658425456,1.0603817720347808,-0.08762466761145592,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,-0.2857688748733796,0.9823261264765617,-0.2567482190180186,0.020605480698360126,4.09320199924866,-0.006127331605984542,0.9823261264765617,0.15115395482942545,-0.8888282886905626,1.6535024833174539,2.857903513986415,-0.4043641190777143,2.199400481282764,-1.1768795353111265,-0.4346601796282852,1.4232989777185565,-0.006127331605984542,-1.139599641176551,0.8408260074769911,1.192389231232484,-0.3150370549937861,-0.4043641190777143,2.0518497400362734,0.22708991471684983,-0.1430695347463049,-0.17113556168396907,-0.1994350717264357,2.6224404188956902,0.1254502957539166,0.3977415176858454,1.2472629393969026,0.5372180454514659,0.07343946733113242,0.047126781746465576,-0.06023936284890438,1.5406396934742081,-0.06023936284890438,0.17666003360338126,1.0216002256059087,0.58240161346863,1.3189165219976549,-0.8202718560579666
| 2,468
|
Ceramide metabolic process
| 11
| 16
| 3.143987
| 0.001667
|
P30153,P04062,O95470,Q96G23,P06865,Q99805,P06280,Q8NCC3,O15269,O15121,Q16739
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
326,236,269,114,209,180,339,88,153,218,92
|
218,153,269,236,339,209,536,609,326,361,92,1105,88,114,180,1723
|
1.1738760097490326,1.4909169970454357,1.0216002256059087,1.117653769245169,0.8408260074769911,1.2107906833937936,0.5372180454514659,0.44490440798943937,0.8819129546814536,0.7991941651751763,2.024171009993822,0.047126781746465576,2.065588110324613,1.807535106013106,1.3189165219976549,-0.4043641190777143
| 2,468
|
Mitochondrial transport
| 19
| 69
| 3.135677
| 0.001715
|
Q99595,Q10713,Q96EK5,P45880,O75964,Q5JRX3,Q9H270,P55786,P23786,Q9NS69,O43772,P52789,O95831,O75431,Q8N4H5,Q9UBX3,P30536,O00170,P49257
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,257,135,7,143,272,274,23,26,29,37,303,298,191,198,199,73,207,119
|
207,413,485,503,37,191,1606,2225,143,1477,837,1339,298,1019,1758,2157,1480,732,1482,2324,811,1303,26,757,2211,2212,1381,73,1090,1346,1967,7,2427,2411,119,2124,327,1735,303,23,2298,1247,257,560,1283,1506,890,456,1105,272,2103,1285,1881,1588,198,135,1713,1630,2,274,1396,2017,29,866,199,1297,1263,1403,1372
|
1.2107906833937936,0.692646228876154,0.6047569844332618,0.58240161346863,2.857903513986415,1.2653360299982175,-0.34455645734238355,-0.994181179090294,1.5733299672243768,-0.2567482190180186,0.22708991471684983,-0.1430695347463049,0.9425484828699386,0.09954637705818221,-0.46522306940850683,-0.8543859267849101,-0.2567482190180186,0.3256911134093675,-0.2567482190180186,-1.2910471139088535,0.25201882658425456,-0.11523365842189977,2.9583317443973955,0.3013170110599651,-0.958720173237647,-0.958720173237647,-0.17113556168396907,2.238325990048142,0.047126781746465576,-0.1430695347463049,-0.65444091817572,3.6667004853346468,-2.156313870988057,-1.83066113592861,1.7468979457042964,-0.8202718560579666,0.8819129546814536,-0.4346601796282852,0.9425484828699386,3.0739178449056257,-1.1768795353111265,-0.06023936284890438,1.0603817720347808,0.5143859578494419,-0.08762466761145592,-0.2567482190180186,0.20197116058474252,0.6490043765907978,0.047126781746465576,1.0216002256059087,-0.7864806683003362,-0.08762466761145592,-0.5585543448403263,-0.3150370549937861,1.2472629393969026,1.6216955230183503,-0.4043641190777143,-0.34455645734238355,4.0993803881071775,1.0216002256059087,-0.17113556168396907,-0.6869921898793442,2.928608323075618,0.22708991471684983,1.2472629393969026,-0.08762466761145592,-0.06023936284890438,-0.17113556168396907,-0.1430695347463049
| 2,468
|
transporter
| 17
| 52
| 3.119998
| 0.001809
|
Q99595,Q8TEX9,Q92973,O43772,P53985,Q9H2D1,Q99805,Q567V2,Q9HD45,Q8NFH4,O15397,P39210,P54105,Q99808,Q92544,Q8N1F7,Q9Y619
|
Functions
|
Panther Protein class
|
panther_protein_class
|
2,387,293,37,40,14,180,17,146,179,296,176,151,342,242,423,125
|
520,1825,655,1119,836,296,503,1637,37,753,1374,1193,1695,612,176,691,2347,509,918,1616,2066,40,151,670,1451,2399,1102,1214,560,17,439,1848,423,179,1854,387,242,293,1857,1221,746,2,180,342,1952,14,650,146,1400,1370,1263,125
|
0.5598892765754294,-0.5271658967301447,0.3977415176858454,0.020605480698360126,0.22708991471684983,0.9425484828699386,0.58240161346863,-0.3743308591385381,2.857903513986415,0.3013170110599651,-0.17113556168396907,-0.033074608598505244,-0.4043641190777143,0.44490440798943937,1.3189165219976549,0.3739010819588171,-1.3691701581343436,0.58240161346863,0.17666003360338126,-0.34455645734238355,-0.7530070814189461,2.827005651000117,1.5075840575864408,0.3977415176858454,-0.22797146657486117,-1.6562527119273847,0.047126781746465576,-0.033074608598505244,0.5143859578494419,3.202482497522664,0.6709000913867084,-0.5271658967301447,0.692646228876154,1.3189165219976549,-0.5271658967301447,0.7570047251940325,1.0986814186639104,0.9625009483378237,-0.5271658967301447,-0.033074608598505244,0.3256911134093675,4.0993803881071775,1.3189165219976549,0.8408260074769911,-0.6221873063453945,3.3671029220870046,0.42140856532916043,1.5406396934742081,-0.17113556168396907,-0.1430695347463049,-0.06023936284890438,1.6692773995529553
| 2,468
|
Ion transmembrane transporter activity
| 22
| 90
| 3.11884
| 0.001816
|
Q8TB61,Q70HW3,P21796,P45880,Q9UDW1,Q9H2D1,O75964,Q9Y277,Q8N4V1,O43772,P53985,Q9HC07,Q9HD20,Q9Y487,P04920,Q9UBX3,Q93050,P33527,P00403,Q9C0H2,Q13423,Q9Y619
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,3,4,7,136,14,143,275,286,37,40,307,47,181,187,199,76,75,324,89,117,125
|
1567,1637,37,534,1411,2225,143,1300,1121,324,187,981,1642,2157,1480,1829,1965,1481,2057,537,1572,491,811,1612,1154,434,1690,2255,914,2171,4,394,757,2211,663,75,666,1346,524,7,2427,2392,2066,40,1245,2298,1702,2399,2008,2070,601,1803,117,453,999,1544,1507,439,2103,1141,1945,3,286,2181,128,1256,76,2011,342,1715,1718,1778,89,863,14,1366,1433,1633,307,834,47,199,136,1117,1297,1563,275,518,181,125
|
-0.3150370549937861,-0.3743308591385381,2.857903513986415,0.5372180454514659,-0.1994350717264357,-0.994181179090294,1.5733299672243768,-0.11523365842189977,0.020605480698360126,0.8819129546814536,1.2833019254548965,0.1254502957539166,-0.3743308591385381,-0.8543859267849101,-0.2567482190180186,-0.5271658967301447,-0.65444091817572,-0.2567482190180186,-0.7530070814189461,0.5372180454514659,-0.3150370549937861,0.6047569844332618,0.25201882658425456,-0.34455645734238355,-0.006127331605984542,0.6709000913867084,-0.4043641190777143,-1.066163090613305,0.17666003360338126,-0.8888282886905626,3.838410894509741,0.7356968204452725,0.3013170110599651,-0.958720173237647,0.3977415176858454,2.199400481282764,0.3977415176858454,-0.1430695347463049,0.5598892765754294,3.6667004853346468,-2.156313870988057,-1.6138737694884546,-0.7530070814189461,2.827005651000117,-0.06023936284890438,-1.1768795353111265,-0.4043641190777143,-1.6562527119273847,-0.6869921898793442,-0.7530070814189461,0.4682311897943023,-0.4960569056469889,1.7773752159481948,0.6490043765907978,0.1254502957539166,-0.2857688748733796,-0.2567482190180186,0.6709000913867084,-0.7864806683003362,0.020605480698360126,-0.6221873063453945,4.09320199924866,0.9823261264765617,-0.8888282886905626,1.6535024833174539,-0.06023936284890438,2.199400481282764,-0.6869921898793442,0.8408260074769911,-0.4043641190777143,-0.4043641190777143,-0.46522306940850683,2.0518497400362734,0.22708991471684983,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,0.9425484828699386,0.25201882658425456,2.6224404188956902,1.2472629393969026,1.6216955230183503,0.047126781746465576,-0.08762466761145592,-0.2857688748733796,1.0216002256059087,0.58240161346863,1.3189165219976549,1.6692773995529553
| 2,468
|
Abnormal circulating lipid concentration
| 17
| 60
| 3.109988
| 0.001871
|
Q13045,O75431,P28070,P37268,O75844,Q8N511,O43772,Q9Y4P3,Q14739,O95470,Q15392,O43707,P49257,P22830,P23786,Q15904,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
248,191,225,131,36,6,37,190,139,269,61,297,119,150,26,284,31
|
1189,297,37,907,191,36,1641,269,1609,339,754,31,1685,2453,150,26,225,1344,576,759,131,396,1275,614,119,1647,818,418,1125,1538,2038,1451,1311,1209,1974,1619,248,1422,139,1137,61,2258,619,284,824,2216,6,1855,1950,2230,1179,1816,1261,628,942,2054,1297,652,1405,190
|
-0.033074608598505244,0.9425484828699386,2.857903513986415,0.17666003360338126,1.2653360299982175,2.868122282262257,-0.3743308591385381,1.0216002256059087,-0.34455645734238355,0.8408260074769911,0.3013170110599651,2.908601987092757,-0.4043641190777143,-3.201455829918393,1.5075840575864408,2.9583317443973955,1.1552498319919475,-0.1430695347463049,0.49139101679695213,0.3013170110599651,1.6376421273678423,0.7356968204452725,-0.08762466761145592,0.44490440798943937,1.7468979457042964,-0.3743308591385381,0.25201882658425456,0.692646228876154,0.020605480698360126,-0.2857688748733796,-0.7198459356446938,-0.22797146657486117,-0.11523365842189977,-0.033074608598505244,-0.65444091817572,-0.34455645734238355,1.0795911798832665,-0.1994350717264357,1.6056618506283145,0.020605480698360126,2.4130652487639477,-1.066163090613305,0.44490440798943937,0.9823261264765617,0.25201882658425456,-0.958720173237647,3.681490447648572,-0.5271658967301447,-0.6221873063453945,-0.994181179090294,-0.006127331605984542,-0.4960569056469889,-0.06023936284890438,0.44490440798943937,0.17666003360338126,-0.7198459356446938,-0.08762466761145592,0.42140856532916043,-0.17113556168396907,1.2833019254548965
| 2,468
|
Hormone metabolic process
| 9
| 24
| 3.098219
| 0.001947
|
O60678,Q9HB40,O75844,O94788,P42892,P30536,O95470,P07858,P16435
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,68,36,102,39,73,269,80,245
|
195,1412,36,102,269,981,80,873,1832,245,73,39,2092,1125,451,1390,305,1662,1983,724,1463,2185,68,942
|
1.2472629393969026,-0.1994350717264357,2.868122282262257,1.8961668597006474,1.0216002256059087,0.1254502957539166,2.1599235408173723,0.20197116058474252,-0.5271658967301447,1.0795911798832665,2.238325990048142,2.827005651000117,-0.7864806683003362,0.020605480698360126,0.6490043765907978,-0.17113556168396907,0.9425484828699386,-0.3743308591385381,-0.65444091817572,0.34988503514948976,-0.22797146657486117,-0.8888282886905626,2.3270814179529142,0.17666003360338126
| 2,468
|
Orc1 removal from chromatin
| 20
| 48
| 3.09449
| 0.001972
|
O00231,Q9UL46,P33991,P60900,Q99436,O43242,P61289,P49736,P49721,P28074,P20618,Q14566,P63208,P33993,P24941,P28070,P49720,Q15008,P28072,Q9Y619
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
251,147,405,408,164,533,436,435,56,54,202,452,470,468,224,225,230,499,373,125
|
251,1266,2221,1226,533,1228,1640,756,202,224,633,1059,1532,1158,1305,1199,225,373,54,405,1060,468,1872,1240,1093,230,56,435,557,994,408,436,845,1279,884,470,821,695,696,2269,452,2215,499,164,1177,147,1265,125
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.06023936284890438,-0.3743308591385381,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.42140856532916043,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,0.7142445586094798,0.07343946733113242,0.6269572845849924,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.6709000913867084,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,0.3739010819588171,-1.1026963504909864,0.6490043765907978,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438,1.6692773995529553
| 2,468
|
Proteasome core complex
| 7
| 14
| 3.092552
| 0.001984
|
P28070,Q99436,P49720,P20618,P49721,P28074,P28072
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
225,164,230,202,56,54,373
|
1226,202,1059,1532,1158,1305,1199,225,373,54,230,56,408,164
|
-0.06023936284890438,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,1.1365094929601929,2.4964247239663777,0.7142445586094798,1.4232989777185565
| 2,468
|
Proteasome, subunit alpha/beta [IPR001353]
| 7
| 14
| 3.092552
| 0.001984
|
P28070,Q99436,P49720,P20618,P49721,P28074,P28072
|
Sequence
|
InterPro Family
|
interpro_family
|
225,164,230,202,56,54,373
|
1226,202,1059,1532,1158,1305,1199,225,373,54,230,56,408,164
|
-0.06023936284890438,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,1.1365094929601929,2.4964247239663777,0.7142445586094798,1.4232989777185565
| 2,468
|
Nucleophile aminohydrolases, N-terminal [IPR029055]
| 7
| 17
| 3.090359
| 0.001999
|
P28070,Q99436,P49720,P20618,P49721,P28074,P28072
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
225,164,230,202,56,54,373
|
1226,912,202,1059,1532,1158,1305,1199,225,373,54,230,56,408,1031,849,164
|
-0.06023936284890438,0.17666003360338126,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,1.1365094929601929,2.4964247239663777,0.7142445586094798,0.09954637705818221,0.22708991471684983,1.4232989777185565
| 2,468
|
Monovalent inorganic cation homeostasis
| 8
| 25
| 3.084857
| 0.002037
|
O75503,Q8N511,Q93050,Q9Y487,Q92544,P50897,Q15904,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,6,76,181,242,112,284,187
|
66,1412,1152,187,981,1642,1480,537,1198,634,112,1934,2283,1245,1702,1313,284,6,242,76,1002,307,903,1117,181
|
2.3395309528321633,-0.1994350717264357,-0.006127331605984542,1.2833019254548965,0.1254502957539166,-0.3743308591385381,-0.2567482190180186,0.5372180454514659,-0.033074608598505244,0.42140856532916043,1.807535106013106,-0.6221873063453945,-1.139599641176551,-0.06023936284890438,-0.4043641190777143,-0.11523365842189977,0.9823261264765617,3.681490447648572,1.0986814186639104,2.199400481282764,0.1254502957539166,0.9425484828699386,0.20197116058474252,0.047126781746465576,1.3189165219976549
| 2,468
|
Organic acid transport
| 11
| 41
| 3.05772
| 0.00223
|
P08183,O43772,Q9UBX3,P53985,Q7L0J3,Q15042,P33527,Q9H2D1,P07814,P23786,Q9Y619
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,37,199,40,41,233,75,14,244,26,125
|
37,534,1054,1411,2056,1121,1996,2373,1757,1963,244,32,1481,491,277,415,26,1490,1999,1835,75,2066,40,1245,1803,1655,233,1544,1141,1945,41,1715,1778,14,1366,1433,1633,199,1297,518,125
|
2.857903513986415,0.5372180454514659,0.07343946733113242,-0.1994350717264357,-0.7530070814189461,0.020605480698360126,-0.6869921898793442,-1.4895231624354457,-0.46522306940850683,-0.65444091817572,1.0795911798832665,2.908601987092757,-0.2567482190180186,0.6047569844332618,1.0020254240102997,0.692646228876154,2.9583317443973955,-0.2567482190180186,-0.6869921898793442,-0.5271658967301447,2.199400481282764,-0.7530070814189461,2.827005651000117,-0.06023936284890438,-0.4960569056469889,-0.3743308591385381,1.1365094929601929,-0.2857688748733796,0.020605480698360126,-0.6221873063453945,2.827005651000117,-0.4043641190777143,-0.46522306940850683,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,1.2472629393969026,-0.08762466761145592,0.58240161346863,1.6692773995529553
| 2,468
|
Cellular monovalent inorganic cation homeostasis
| 8
| 24
| 3.047195
| 0.00231
|
O75503,Q8N511,Q93050,Q9Y487,Q92544,P50897,Q15904,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,6,76,181,242,112,284,187
|
66,1412,187,981,1642,1480,537,1198,634,112,1934,2283,1245,1702,1313,284,6,242,76,1002,307,903,1117,181
|
2.3395309528321633,-0.1994350717264357,1.2833019254548965,0.1254502957539166,-0.3743308591385381,-0.2567482190180186,0.5372180454514659,-0.033074608598505244,0.42140856532916043,1.807535106013106,-0.6221873063453945,-1.139599641176551,-0.06023936284890438,-0.4043641190777143,-0.11523365842189977,0.9823261264765617,3.681490447648572,1.0986814186639104,2.199400481282764,0.1254502957539166,0.9425484828699386,0.20197116058474252,0.047126781746465576,1.3189165219976549
| 2,468
|
Exopeptidase activity
| 10
| 27
| 3.043081
| 0.002342
|
O75844,Q9HB40,P42785,Q9H3G5,O14773,P10619,P55786,O75976,Q9UIQ6,P50579
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
36,68,8,74,141,81,23,276,58,28
|
141,36,276,432,283,81,2416,2334,2031,879,8,28,23,1455,794,1356,440,827,1142,1910,74,1007,68,1862,940,427,58
|
1.5895402794086952,2.868122282262257,1.0020254240102997,0.6709000913867084,0.9823261264765617,2.1599235408173723,-1.9209411773807756,-1.3299025873109733,-0.7198459356446938,0.20197116058474252,3.5056872507526013,2.928608323075618,3.0739178449056257,-0.22797146657486117,0.27676037958362715,-0.1430695347463049,0.6709000913867084,0.25201882658425456,0.020605480698360126,-0.590226648688484,2.2254112620780373,0.1254502957539166,2.3270814179529142,-0.5271658967301447,0.17666003360338126,0.692646228876154,2.4728673792906726
| 2,468
|
Sphingolipid metabolism
| 12
| 23
| 3.038857
| 0.002375
|
Q06136,P04062,O95470,Q96G23,P10619,P16278,P06865,P06280,O15269,O15121,Q16739,P07602
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
98,236,269,114,81,18,209,339,153,218,92,31
|
218,153,1637,2239,269,236,339,209,31,536,81,18,609,1797,638,98,361,92,114,2015,1723,628,1916
|
1.1738760097490326,1.4909169970454357,-0.3743308591385381,-1.0299934512102915,1.0216002256059087,1.117653769245169,0.8408260074769911,1.2107906833937936,2.908601987092757,0.5372180454514659,2.1599235408173723,3.1754755052007098,0.44490440798943937,-0.4960569056469889,0.42140856532916043,1.9251128862095315,0.7991941651751763,2.024171009993822,1.807535106013106,-0.6869921898793442,-0.4043641190777143,0.44490440798943937,-0.590226648688484
| 2,468
|
Protein targeting to mitochondrion
| 14
| 37
| 3.038581
| 0.002377
|
Q99595,Q10713,Q3ZCQ8,Q8N4H5,P30536,O14737,O00170,Q5JRX3,O14925,Q9H270,O95831,P49257,P55786,Q9NS69
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,257,456,198,73,413,207,272,485,274,298,119,23,29
|
207,413,485,503,1606,1477,837,1339,298,1019,732,2324,1303,73,1090,119,2124,1735,23,1247,257,1283,1506,456,1105,272,1285,198,1630,2,274,1396,2017,29,866,1403,1372
|
1.2107906833937936,0.692646228876154,0.6047569844332618,0.58240161346863,-0.34455645734238355,-0.2567482190180186,0.22708991471684983,-0.1430695347463049,0.9425484828699386,0.09954637705818221,0.3256911134093675,-1.2910471139088535,-0.11523365842189977,2.238325990048142,0.047126781746465576,1.7468979457042964,-0.8202718560579666,-0.4346601796282852,3.0739178449056257,-0.06023936284890438,1.0603817720347808,-0.08762466761145592,-0.2567482190180186,0.6490043765907978,0.047126781746465576,1.0216002256059087,-0.08762466761145592,1.2472629393969026,-0.34455645734238355,4.0993803881071775,1.0216002256059087,-0.17113556168396907,-0.6869921898793442,2.928608323075618,0.22708991471684983,-0.17113556168396907,-0.1430695347463049
| 2,468
|
Cytoprotection by hmox1
| 23
| 59
| 3.029662
| 0.002448
|
O00231,P09601,Q9UL46,P60900,P30519,Q99436,O43242,P40763,P09669,Q8TCT9,P49721,P61289,P28074,P00403,P33527,P20618,Q86X55,P63208,P28070,P49720,Q15008,Q9BZK7,P28072
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
251,522,147,408,27,164,533,416,175,314,56,436,54,324,75,202,210,470,225,230,499,265,373
|
251,1266,2151,2221,1226,533,1299,1640,1641,324,522,175,1572,1154,1687,756,1303,202,2255,1059,1532,1158,1305,1199,225,373,54,27,75,1872,416,1578,1240,1093,230,56,557,1837,994,408,436,845,1279,884,470,821,695,2269,793,2215,499,210,314,1395,164,1177,265,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.8543859267849101,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.11523365842189977,-0.3743308591385381,-0.3743308591385381,0.8819129546814536,0.5598892765754294,1.3189165219976549,-0.3150370549937861,-0.006127331605984542,-0.4043641190777143,0.3013170110599651,-0.11523365842189977,1.2290815354843998,-1.066163090613305,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,2.928608323075618,2.199400481282764,-0.5585543448403263,0.692646228876154,-0.3150370549937861,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,-0.5271658967301447,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,0.27676037958362715,-0.958720173237647,0.6047569844332618,1.2107906833937936,0.9224673008330843,-0.17113556168396907,1.4232989777185565,-0.006127331605984542,1.0603817720347808,1.5406396934742081,-0.06023936284890438
| 2,468
|
Antigen processing ubiquitination proteasome degradation
| 13
| 76
| 3.02929
| 0.002451
|
Q16763,A0AVT1,P28070,Q99436,P49720,P52888,P20618,P19474,Q9UL46,P49721,P55786,P28074,Q9UIQ6
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
260,159,225,164,230,12,202,50,147,56,23,54,58
|
159,251,1266,2221,1226,533,1640,1192,1339,756,50,202,984,1059,1532,1158,1305,1199,225,373,54,2031,1492,1872,1240,1093,407,230,56,557,12,994,23,408,1540,2174,1350,436,845,1279,884,470,1247,1313,821,695,2269,1249,793,794,2044,2215,499,1034,1909,927,260,2048,1107,1285,1287,623,1256,898,164,1177,680,703,58,710,1013,774,147,630,1265,776
|
1.457299817470005,1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,-0.033074608598505244,-0.1430695347463049,0.3013170110599651,2.5658905492788504,1.2290815354843998,0.1254502957539166,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.7198459356446938,-0.2567482190180186,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,0.7142445586094798,1.1365094929601929,2.4964247239663777,0.5143859578494419,3.4332901983397086,0.1254502957539166,3.0739178449056257,0.7142445586094798,-0.2857688748733796,-0.8888282886905626,-0.1430695347463049,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,-0.06023936284890438,-0.11523365842189977,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.06023936284890438,0.27676037958362715,0.27676037958362715,-0.7198459356446938,-0.958720173237647,0.6047569844332618,0.09954637705818221,-0.590226648688484,0.17666003360338126,1.0603817720347808,-0.7198459356446938,0.047126781746465576,-0.08762466761145592,-0.08762466761145592,0.44490440798943937,-0.06023936284890438,0.20197116058474252,1.4232989777185565,-0.006127331605984542,0.3977415176858454,0.3739010819588171,2.4728673792906726,0.3739010819588171,0.1254502957539166,0.3013170110599651,1.5406396934742081,0.44490440798943937,-0.06023936284890438,0.3013170110599651
| 2,468
|
Protein localization to mitochondrion
| 17
| 47
| 3.017091
| 0.002552
|
Q99595,Q10713,Q3ZCQ8,Q8N4H5,P30536,P52789,O14737,O00429,O00170,Q5JRX3,O14925,Q9H270,O95831,P49257,P55786,P31689,Q9NS69
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,257,456,198,73,303,413,412,207,272,485,274,298,119,23,374,29
|
207,835,412,413,485,503,1606,1477,837,1339,298,1019,732,608,2324,2199,1688,1303,1381,73,374,1090,119,2124,1735,303,23,1247,257,560,1283,1506,456,1105,272,1285,198,1630,2,274,1396,2017,29,866,1403,1372,1437
|
1.2107906833937936,0.22708991471684983,0.692646228876154,0.692646228876154,0.6047569844332618,0.58240161346863,-0.34455645734238355,-0.2567482190180186,0.22708991471684983,-0.1430695347463049,0.9425484828699386,0.09954637705818221,0.3256911134093675,0.44490440798943937,-1.2910471139088535,-0.9236044800386676,-0.4043641190777143,-0.11523365842189977,-0.17113556168396907,2.238325990048142,0.7781699552447922,0.047126781746465576,1.7468979457042964,-0.8202718560579666,-0.4346601796282852,0.9425484828699386,3.0739178449056257,-0.06023936284890438,1.0603817720347808,0.5143859578494419,-0.08762466761145592,-0.2567482190180186,0.6490043765907978,0.047126781746465576,1.0216002256059087,-0.08762466761145592,1.2472629393969026,-0.34455645734238355,4.0993803881071775,1.0216002256059087,-0.17113556168396907,-0.6869921898793442,2.928608323075618,0.22708991471684983,-0.17113556168396907,-0.1430695347463049,-0.1994350717264357
| 2,468
|
Carboxylic acid transport
| 8
| 32
| 3.001653
| 0.002685
|
Q9UBX3,P53985,Q7L0J3,Q15042,P33527,Q9H2D1,Q9Y619,P07602
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
199,40,41,233,75,14,125,31
|
1054,1411,2056,1121,1757,1963,31,1481,277,415,1490,75,2066,40,1245,1803,1655,233,1544,1141,41,1715,1778,14,1366,1433,1633,628,199,1297,518,125
|
0.07343946733113242,-0.1994350717264357,-0.7530070814189461,0.020605480698360126,-0.46522306940850683,-0.65444091817572,2.908601987092757,-0.2567482190180186,1.0020254240102997,0.692646228876154,-0.2567482190180186,2.199400481282764,-0.7530070814189461,2.827005651000117,-0.06023936284890438,-0.4960569056469889,-0.3743308591385381,1.1365094929601929,-0.2857688748733796,0.020605480698360126,2.827005651000117,-0.4043641190777143,-0.46522306940850683,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,0.44490440798943937,1.2472629393969026,-0.08762466761145592,0.58240161346863,1.6692773995529553
| 2,468
|
Switching of origins to a post replicative state
| 26
| 54
| 2.999677
| 0.002703
|
Q16763,O00231,P25205,Q9UL46,P33991,P60900,Q99436,O43242,Q9H1A4,P51665,P61289,P49736,P49721,Q9UJX2,P28074,Q13416,P20618,Q14566,P63208,P33993,P24941,P28070,P49720,Q15008,P28072,Q9Y619
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
260,251,633,147,405,408,164,533,703,557,436,435,56,710,54,696,202,452,470,468,224,225,230,499,373,125
|
251,1266,2221,1226,533,1228,1640,756,202,224,633,1059,1532,1158,1305,1199,225,373,54,1492,405,1060,468,1872,1240,1093,230,56,435,557,994,408,436,845,1279,884,470,821,695,696,2269,452,2215,499,260,164,1177,703,710,1013,774,147,1265,125
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.06023936284890438,-0.3743308591385381,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.42140856532916043,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.2567482190180186,0.7142445586094798,0.07343946733113242,0.6269572845849924,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.6709000913867084,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,0.3739010819588171,-1.1026963504909864,0.6490043765907978,-0.958720173237647,0.6047569844332618,1.0603817720347808,1.4232989777185565,-0.006127331605984542,0.3739010819588171,0.3739010819588171,0.1254502957539166,0.3013170110599651,1.5406396934742081,-0.06023936284890438,1.6692773995529553
| 2,468
|
Metallopeptidase activity
| 12
| 35
| 2.978022
| 0.002901
|
Q10713,O75844,P42892,Q9BYT8,P52888,Q5JRX3,P55786,O75976,Q9UIQ6,P22695,P50579,Q92905
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
257,36,39,250,12,272,23,276,58,59,28,263
|
682,2221,572,345,1606,36,276,432,283,2416,873,59,2334,879,39,28,557,12,23,257,272,1547,930,1356,263,1142,1746,1910,250,1007,1862,940,427,58,2150
|
0.3739010819588171,-0.994181179090294,0.49139101679695213,0.8200789823454424,-0.34455645734238355,2.868122282262257,1.0020254240102997,0.6709000913867084,0.9823261264765617,-1.9209411773807756,0.20197116058474252,2.461011602486414,-1.3299025873109733,0.20197116058474252,2.827005651000117,2.928608323075618,0.5143859578494419,3.4332901983397086,3.0739178449056257,1.0603817720347808,1.0216002256059087,-0.2857688748733796,0.17666003360338126,-0.1430695347463049,1.0603817720347808,0.020605480698360126,-0.4346601796282852,-0.590226648688484,1.0795911798832665,0.1254502957539166,-0.5271658967301447,0.17666003360338126,0.692646228876154,2.4728673792906726,-0.8202718560579666
| 2,468
|
Alzheimers disease and mirna effects
| 28
| 76
| 2.975154
| 0.002928
|
P21796,P45880,Q9Y277,O14654,P60900,Q99436,O43242,O95197,P07437,P51665,P49721,P16615,P28074,P68371,Q9BVA1,Q9NQC3,P49841,P20618,P04350,Q00535,Q13885,P28070,Q96GC9,P49720,Q9NSK0,Q15008,P05198,P28072
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
4,7,275,521,408,164,533,168,299,557,56,434,54,312,458,331,327,202,333,601,618,225,624,230,107,499,490,373
|
1266,2221,521,1226,533,168,333,2027,2157,490,1644,299,608,811,1612,873,434,756,983,1303,202,4,1059,1532,1158,1305,1198,1199,225,373,54,634,2212,815,1533,1872,784,1614,2035,1240,7,1093,1124,1094,230,56,327,557,994,408,845,1279,884,312,601,1542,792,850,695,767,618,499,2181,1665,624,1712,164,1177,1178,2185,726,458,331,107,1265,275
|
-0.08762466761145592,-0.994181179090294,0.5598892765754294,-0.06023936284890438,0.5372180454514659,1.3715614817905903,0.8614368152158327,-0.7198459356446938,-0.8543859267849101,0.6047569844332618,-0.3743308591385381,0.9425484828699386,0.44490440798943937,0.25201882658425456,-0.34455645734238355,0.20197116058474252,0.6709000913867084,0.3013170110599651,0.1254502957539166,-0.11523365842189977,1.2290815354843998,3.838410894509741,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,0.42140856532916043,-0.958720173237647,0.25201882658425456,-0.2857688748733796,-0.5585543448403263,0.27676037958362715,-0.34455645734238355,-0.7198459356446938,-0.06023936284890438,3.6667004853346468,0.047126781746465576,0.020605480698360126,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.8819129546814536,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.9224673008330843,0.4682311897943023,-0.2857688748733796,0.27676037958362715,0.22708991471684983,0.3739010819588171,0.3013170110599651,0.44490440798943937,0.6047569844332618,-0.8888282886905626,-0.3743308591385381,0.44490440798943937,-0.4043641190777143,1.4232989777185565,-0.006127331605984542,-0.006127331605984542,-0.8888282886905626,0.34988503514948976,0.6490043765907978,0.8819129546814536,1.8521923010037062,-0.06023936284890438,1.0216002256059087
| 2,468
|
Sphingolipid metabolism in senescence
| 8
| 12
| 2.974675
| 0.002933
|
P24941,Q06136,P11802,Q96G23,P16278,O15269,O15121,Q16739
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
224,98,223,114,18,153,218,92
|
218,153,236,223,18,224,634,1614,98,361,92,114
|
1.1738760097490326,1.4909169970454357,1.117653769245169,1.1552498319919475,3.1754755052007098,1.1552498319919475,0.42140856532916043,-0.34455645734238355,1.9251128862095315,0.7991941651751763,2.024171009993822,1.807535106013106
| 2,468
|
Copi mediated anterograde transport
| 27
| 50
| 2.965694
| 0.00302
|
P24390,P35606,Q9Y678,Q15363,P68371,O14653,Q9BVA1,Q13561,P49755,Q14789,Q13813,P04350,Q9BUF5,Q12893,Q92538,Q9UJW0,Q08379,Q13885,Q9BVK6,P63167,Q9Y3B3,Q9Y3Q3,Q14203,Q99747,O75935,P62820,P61923
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
5,291,295,698,312,683,458,328,692,584,582,333,726,350,476,355,471,618,747,737,367,368,498,501,108,359,764
|
750,683,870,1681,1476,108,333,1528,5,291,2123,1203,817,881,692,1243,1126,843,1971,1063,764,359,737,312,1030,471,350,1650,923,1622,328,582,618,498,1213,584,698,1110,476,1327,501,726,458,747,1597,355,367,368,295,1082
|
0.3013170110599651,0.3739010819588171,0.20197116058474252,-0.4043641190777143,-0.2567482190180186,1.8373833245061917,0.8614368152158327,-0.2857688748733796,3.8314985860427604,0.9625009483378237,-0.8202718560579666,-0.033074608598505244,0.25201882658425456,0.20197116058474252,0.3739010819588171,-0.06023936284890438,0.020605480698360126,0.22708991471684983,-0.65444091817572,0.07343946733113242,0.3013170110599651,0.7991941651751763,0.3256911134093675,0.9224673008330843,0.09954637705818221,0.6269572845849924,0.8200789823454424,-0.3743308591385381,0.17666003360338126,-0.34455645734238355,0.8819129546814536,0.49139101679695213,0.44490440798943937,0.6047569844332618,-0.033074608598505244,0.49139101679695213,0.3739010819588171,0.047126781746465576,0.6269572845849924,-0.11523365842189977,0.6047569844332618,0.34988503514948976,0.6490043765907978,0.3256911134093675,-0.3150370549937861,0.8200789823454424,0.7991941651751763,0.7991941651751763,0.9625009483378237,0.07343946733113242
| 2,468
|
Anion transmembrane transporter activity
| 17
| 41
| 2.962717
| 0.003049
|
Q8TB61,P0CG08,P21796,P45880,P53985,Q9UBX3,Q14728,P33527,Q9H2D1,Q9Y277,Q6N075,Q99808,P11166,Q9Y619,Q9C0H2,P04920,Q9Y289
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,537,4,7,40,199,453,75,14,275,439,342,491,125,89,187,518
|
1567,1637,534,1411,1121,187,2157,1481,537,491,811,1612,4,75,7,2392,2066,40,1245,1803,453,1544,1507,439,2103,1141,128,342,1715,1778,89,14,1366,1433,1633,834,199,1297,275,518,125
|
-0.3150370549937861,-0.3743308591385381,0.5372180454514659,-0.1994350717264357,0.020605480698360126,1.2833019254548965,-0.8543859267849101,-0.2567482190180186,0.5372180454514659,0.6047569844332618,0.25201882658425456,-0.34455645734238355,3.838410894509741,2.199400481282764,3.6667004853346468,-1.6138737694884546,-0.7530070814189461,2.827005651000117,-0.06023936284890438,-0.4960569056469889,0.6490043765907978,-0.2857688748733796,-0.2567482190180186,0.6709000913867084,-0.7864806683003362,0.020605480698360126,1.6535024833174539,0.8408260074769911,-0.4043641190777143,-0.46522306940850683,2.0518497400362734,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,0.25201882658425456,1.2472629393969026,-0.08762466761145592,1.0216002256059087,0.58240161346863,1.6692773995529553
| 2,468
|
Cilium assembly
| 24
| 48
| 2.961733
| 0.003059
|
A6NIH7,Q10713,Q92973,Q15154,P07437,P43034,Q15691,P68371,O95684,Q9BVA1,Q13561,P30153,P04350,Q8IYI6,P61981,Q92538,Q13885,Q14203,P78371,Q9UPT5,O75935,A0AVF1,P48643,Q9H6D7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
1,257,293,165,299,556,313,312,60,458,328,326,333,211,600,476,618,498,497,502,108,356,614,118
|
356,1,108,60,333,781,299,732,1155,1197,1528,326,2091,760,556,614,1025,819,1095,1737,1063,600,996,737,312,497,257,1622,328,618,1211,498,1213,641,165,313,211,2408,2310,476,293,1327,726,1180,458,118,1670,502
|
0.7991941651751763,4.1239287394808555,1.8373833245061917,2.43714387569957,0.8614368152158327,0.27676037958362715,0.9425484828699386,0.3256911134093675,-0.006127331605984542,-0.033074608598505244,-0.2857688748733796,0.8819129546814536,-0.7864806683003362,0.3013170110599651,0.5143859578494419,0.44490440798943937,0.09954637705818221,0.25201882658425456,0.047126781746465576,-0.4346601796282852,0.07343946733113242,0.4682311897943023,0.1254502957539166,0.3256911134093675,0.9224673008330843,0.6047569844332618,1.0603817720347808,-0.34455645734238355,0.8819129546814536,0.44490440798943937,-0.033074608598505244,0.6047569844332618,-0.033074608598505244,0.42140856532916043,1.4061522919477702,0.9224673008330843,1.2107906833937936,-1.7863055278776567,-1.214542773220608,0.6269572845849924,0.9625009483378237,-0.11523365842189977,0.34988503514948976,-0.006127331605984542,0.6490043765907978,1.7621766159448307,-0.3743308591385381,0.6047569844332618
| 2,468
|
Phospholipid binding
| 23
| 67
| 2.951873
| 0.003159
|
P21796,O43633,P45880,O14773,P07602,Q9UNH7,P21359,Q8WTV0,Q8N668,P09429,Q9H6U6,Q9Y4G8,Q8IYI6,Q14108,Q92538,Q8NCC3,O60749,Q86YQ8,P53367,O14964,P50897,Q13045,Q9BZF1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
4,504,7,141,31,428,415,38,292,319,480,484,211,84,476,88,464,500,237,487,112,248,264
|
141,487,870,684,504,1409,553,1638,464,953,1757,1829,31,1272,1965,319,1444,1445,2294,1833,415,4,1797,1575,611,612,7,1276,1162,691,112,1205,1736,237,1030,248,1065,84,742,2135,1505,2074,857,500,211,292,88,38,476,895,1461,1910,1143,2015,264,1365,1598,480,628,1956,1263,1331,530,428,1866,484,1790
|
1.5895402794086952,0.6047569844332618,0.20197116058474252,0.3739010819588171,0.58240161346863,-0.1994350717264357,0.5143859578494419,-0.3743308591385381,0.6269572845849924,0.15115395482942545,-0.46522306940850683,-0.5271658967301447,2.908601987092757,-0.08762466761145592,-0.65444091817572,0.9022559500015589,-0.22797146657486117,-0.22797146657486117,-1.1768795353111265,-0.5271658967301447,0.692646228876154,3.838410894509741,-0.4960569056469889,-0.3150370549937861,0.44490440798943937,0.44490440798943937,3.6667004853346468,-0.08762466761145592,-0.006127331605984542,0.3739010819588171,1.807535106013106,-0.033074608598505244,-0.4346601796282852,1.117653769245169,0.09954637705818221,1.0795911798832665,0.07343946733113242,2.119881427808456,0.3256911134093675,-0.8202718560579666,-0.2567482190180186,-0.7530070814189461,0.22708991471684983,0.6047569844332618,1.2107906833937936,0.9625009483378237,2.065588110324613,2.857903513986415,0.6269572845849924,0.20197116058474252,-0.22797146657486117,-0.590226648688484,0.020605480698360126,-0.6869921898793442,1.0603817720347808,-0.1430695347463049,-0.3150370549937861,0.6269572845849924,0.44490440798943937,-0.6221873063453945,-0.06023936284890438,-0.11523365842189977,0.5598892765754294,0.692646228876154,-0.5271658967301447,0.6269572845849924,-0.46522306940850683
| 2,468
|
Serine hydrolase activity
| 8
| 16
| 2.946055
| 0.003219
|
Q9HB40,P42785,Q9H3G5,P67812,Q4J6C6,O14773,Q5JRX3,P10619
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
68,8,74,173,174,141,272,81
|
141,276,81,1235,2031,1696,8,1899,1616,173,455,174,272,1396,74,68
|
1.5895402794086952,1.0020254240102997,2.1599235408173723,-0.06023936284890438,-0.7198459356446938,-0.4043641190777143,3.5056872507526013,-0.590226648688484,-0.34455645734238355,1.3365673787376733,0.6490043765907978,1.3365673787376733,1.0216002256059087,-0.17113556168396907,2.2254112620780373,2.3270814179529142
| 2,468
|
Alzheimers disease
| 27
| 74
| 2.944651
| 0.003233
|
P21796,P45880,Q9Y277,O14654,P60900,Q99436,O43242,O95197,P07437,P51665,P49721,P16615,P28074,P68371,Q9BVA1,Q9NQC3,P49841,P20618,P04350,Q00535,Q13885,P28070,P49720,Q9NSK0,Q15008,P05198,P28072
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
4,7,275,521,408,164,533,168,299,557,56,434,54,312,458,331,327,202,333,601,618,225,230,107,499,490,373
|
1266,2221,521,1226,533,168,333,2027,2157,490,1644,299,608,811,1612,873,434,756,983,1303,202,4,1059,1532,1158,1305,1198,1199,225,373,54,634,2212,815,1533,1872,784,1614,2035,1240,7,1093,1124,1094,230,56,327,557,994,408,845,1279,884,312,601,1542,792,850,695,767,618,499,2181,1665,164,1177,1178,2185,726,458,331,107,1265,275
|
-0.08762466761145592,-0.994181179090294,0.5598892765754294,-0.06023936284890438,0.5372180454514659,1.3715614817905903,0.8614368152158327,-0.7198459356446938,-0.8543859267849101,0.6047569844332618,-0.3743308591385381,0.9425484828699386,0.44490440798943937,0.25201882658425456,-0.34455645734238355,0.20197116058474252,0.6709000913867084,0.3013170110599651,0.1254502957539166,-0.11523365842189977,1.2290815354843998,3.838410894509741,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,0.42140856532916043,-0.958720173237647,0.25201882658425456,-0.2857688748733796,-0.5585543448403263,0.27676037958362715,-0.34455645734238355,-0.7198459356446938,-0.06023936284890438,3.6667004853346468,0.047126781746465576,0.020605480698360126,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.8819129546814536,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.9224673008330843,0.4682311897943023,-0.2857688748733796,0.27676037958362715,0.22708991471684983,0.3739010819588171,0.3013170110599651,0.44490440798943937,0.6047569844332618,-0.8888282886905626,-0.3743308591385381,1.4232989777185565,-0.006127331605984542,-0.006127331605984542,-0.8888282886905626,0.34988503514948976,0.6490043765907978,0.8819129546814536,1.8521923010037062,-0.06023936284890438,1.0216002256059087
| 2,468
|
Hydrolase activity acting on glycosyl bonds
| 9
| 22
| 2.936598
| 0.003318
|
O75503,Q9NUJ1,P04062,P06865,P16278,Q9BTY2,O60502,P23396,P04066
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
66,72,236,209,18,152,25,311,310
|
729,2193,25,66,236,310,339,209,536,1234,982,18,609,311,1380,596,759,693,1623,1767,152,72
|
0.3256911134093675,-0.9236044800386676,2.9583317443973955,2.3395309528321633,1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,0.5372180454514659,-0.06023936284890438,0.1254502957539166,3.1754755052007098,0.44490440798943937,0.9224673008330843,-0.17113556168396907,0.4682311897943023,0.3013170110599651,0.3739010819588171,-0.34455645734238355,-0.46522306940850683,1.5075840575864408,2.2511809259257114
| 2,468
|
Endoplasmic reticulum golgi intermediate compartment
| 12
| 41
| 2.928601
| 0.003405
|
P80303,P09429,P24390,Q8N511,Q9Y678,Q9Y3Q3,Q02818,Q10472,O15258,Q9Y282,P49257,Q15904
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
64,319,5,6,295,368,137,138,208,21,119,284
|
683,208,1681,2086,1086,319,5,2030,840,119,692,1969,1735,1126,1244,64,137,998,471,138,1741,923,584,1979,698,284,1457,6,476,1775,624,1291,747,1597,2112,903,21,946,367,368,295
|
0.3739010819588171,1.2107906833937936,-0.4043641190777143,-0.7864806683003362,0.047126781746465576,0.9022559500015589,3.8314985860427604,-0.7198459356446938,0.22708991471684983,1.7468979457042964,0.3739010819588171,-0.65444091817572,-0.4346601796282852,0.020605480698360126,-0.06023936284890438,2.3642621621233513,1.6056618506283145,0.1254502957539166,0.6269572845849924,1.6056618506283145,-0.4346601796282852,0.17666003360338126,0.49139101679695213,-0.65444091817572,0.3739010819588171,0.9823261264765617,-0.22797146657486117,3.681490447648572,0.6269572845849924,-0.46522306940850683,0.44490440798943937,-0.08762466761145592,0.3256911134093675,-0.3150370549937861,-0.7864806683003362,0.20197116058474252,3.129814463490708,0.17666003360338126,0.7991941651751763,0.7991941651751763,0.9625009483378237
| 2,468
|
Scf skp2 mediated degradation of p27 p21
| 16
| 39
| 2.919186
| 0.003509
|
P24941,P28070,Q99436,O43242,O00231,P11802,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
224,225,164,533,251,223,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,223,756,202,224,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,470,821,695,2269,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,1.1552498319919475,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
serine protease
| 6
| 15
| 2.913668
| 0.003572
|
Q9HB40,P42785,Q9H3G5,P67812,O14773,P10619
|
Functions
|
Panther Protein class
|
panther_protein_class
|
68,8,74,173,141,81
|
141,81,838,1235,2031,1696,8,1899,173,455,174,1396,74,68,568
|
1.5895402794086952,2.1599235408173723,0.22708991471684983,-0.06023936284890438,-0.7198459356446938,-0.4043641190777143,3.5056872507526013,-0.590226648688484,1.3365673787376733,0.6490043765907978,1.3365673787376733,-0.17113556168396907,2.2254112620780373,2.3270814179529142,0.5143859578494419
| 2,468
|
Cyclin a cdk2 associated events at s phase entry
| 16
| 40
| 2.91329
| 0.003576
|
P24941,P28070,Q99436,O43242,O00231,P11802,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
224,225,164,533,251,223,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,223,756,202,224,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,470,821,963,695,2269,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,1.1552498319919475,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.15115395482942545,0.3739010819588171,-1.1026963504909864,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Predicted secreted proteins
| 18
| 40
| 2.909074
| 0.003625
|
O00584,Q9NZ08,P80303,P09429,Q9HB40,Q08380,Q02818,P43490,Q9UMX5,Q15165,P26583,P07858,Q9BTY2,P84157,P14174,Q8WUJ1,Q9Y4P3,O60888
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
281,427,64,319,68,247,137,106,140,48,395,80,152,278,277,86,190,219
|
281,219,1230,1794,658,432,1757,1301,1829,80,319,1997,277,873,1896,395,106,1163,843,1838,579,64,278,137,674,247,1130,1765,48,2142,86,1775,2313,152,1007,2431,68,427,140,190
|
0.9823261264765617,1.1738760097490326,-0.06023936284890438,-0.4960569056469889,0.3977415176858454,0.6709000913867084,-0.46522306940850683,-0.11523365842189977,-0.5271658967301447,2.1599235408173723,0.9022559500015589,-0.6869921898793442,1.0020254240102997,0.20197116058474252,-0.590226648688484,0.7356968204452725,1.8521923010037062,-0.006127331605984542,0.22708991471684983,-0.5271658967301447,0.49139101679695213,2.3642621621233513,1.0020254240102997,1.6056618506283145,0.3977415176858454,1.0795911798832665,0.020605480698360126,-0.46522306940850683,2.5886536324101614,-0.8202718560579666,2.0928656928366243,-0.46522306940850683,-1.214542773220608,1.5075840575864408,0.1254502957539166,-2.254584687983832,2.3270814179529142,0.692646228876154,1.6056618506283145,1.2833019254548965
| 2,468
|
Golgi apparatus
| 41
| 126
| 2.898385
| 0.003751
|
P24390,O00231,O43760,Q02818,O43493,Q8IXU6,Q6NT16,Q69YN2,P16278,Q9HD45,Q8IZA0,P35606,Q9Y678,P51570,O75122,Q9HC07,Q8N4Q0,P67812,Q8NC54,P80303,Q9UBU6,P50851,Q9HB40,Q93050,Q8TD16,O15258,Q8NCH0,Q8TBA6,Q12893,Q92538,Q86Y82,Q08379,Q92896,P11717,P52701,Q9Y3Q3,O00461,P53367,Q9NR09,P50897,O60637
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
5,251,383,137,266,13,15,273,18,146,285,291,295,418,414,307,45,173,183,64,65,193,68,76,206,208,85,475,350,476,474,471,94,221,348,368,101,237,110,112,111
|
1049,1118,835,251,101,750,683,809,1407,978,1051,208,605,1792,266,1726,383,952,111,1476,1191,414,1828,1756,659,1479,2437,522,838,221,18,1574,1797,5,874,758,1834,576,291,666,636,2316,2123,1348,881,692,1497,193,112,418,348,1736,237,1126,843,993,882,173,64,2008,1030,137,527,471,1619,1314,350,923,1135,584,1877,2446,544,273,2203,15,2228,473,588,2401,1070,1172,474,1358,13,285,1109,45,1110,183,85,2143,475,206,2010,476,94,1256,76,724,1513,772,830,548,1075,2300,1597,704,1007,899,68,307,1042,146,110,706,627,1469,748,65,2292,1786,1956,368,2278,295
|
0.07343946733113242,0.020605480698360126,0.22708991471684983,1.0603817720347808,1.8961668597006474,0.3013170110599651,0.3739010819588171,0.25201882658425456,-0.1994350717264357,0.1254502957539166,0.07343946733113242,1.2107906833937936,0.44490440798943937,-0.4960569056469889,1.0410518943199942,-0.4346601796282852,0.7570047251940325,0.15115395482942545,1.807535106013106,-0.2567482190180186,-0.033074608598505244,0.692646228876154,-0.5271658967301447,-0.46522306940850683,0.3977415176858454,-0.2567482190180186,-2.406736711092555,0.5598892765754294,0.22708991471684983,1.1738760097490326,3.1754755052007098,-0.3150370549937861,-0.4960569056469889,3.8314985860427604,0.20197116058474252,0.3013170110599651,-0.5271658967301447,0.49139101679695213,0.9625009483378237,0.3977415176858454,0.42140856532916043,-1.2525962685132521,-0.8202718560579666,-0.1430695347463049,0.20197116058474252,0.3739010819588171,-0.2567482190180186,1.2653360299982175,1.807535106013106,0.692646228876154,0.8200789823454424,-0.4346601796282852,1.117653769245169,0.020605480698360126,0.22708991471684983,0.1254502957539166,0.20197116058474252,1.3365673787376733,2.3642621621233513,-0.6869921898793442,0.09954637705818221,1.6056618506283145,0.5598892765754294,0.6269572845849924,-0.34455645734238355,-0.11523365842189977,0.8200789823454424,0.17666003360338126,0.020605480698360126,0.49139101679695213,-0.5585543448403263,-2.959510953601851,0.5372180454514659,1.0216002256059087,-0.9236044800386676,3.3248211178078995,-0.994181179090294,0.6269572845849924,0.49139101679695213,-1.6991112558978363,0.07343946733113242,-0.006127331605984542,0.6269572845849924,-0.1430695347463049,3.383816314422708,0.9823261264765617,0.047126781746465576,2.6558060787814783,0.047126781746465576,1.3011617275508496,2.119881427808456,-0.8202718560579666,0.6269572845849924,1.2290815354843998,-0.6869921898793442,0.6269572845849924,1.9821392383520264,-0.06023936284890438,2.199400481282764,0.34988503514948976,-0.2567482190180186,0.3013170110599651,0.25201882658425456,0.5372180454514659,0.07343946733113242,-1.1768795353111265,-0.3150370549937861,0.3739010819588171,0.1254502957539166,0.20197116058474252,2.3270814179529142,0.9425484828699386,0.09954637705818221,1.5406396934742081,1.8224978231489162,0.3739010819588171,0.44490440798943937,-0.22797146657486117,0.3256911134093675,2.351924388044598,-1.139599641176551,-0.46522306940850683,-0.6221873063453945,0.7991941651751763,-1.1026963504909864,0.9625009483378237
| 2,468
|
Abc family proteins mediated transport
| 17
| 48
| 2.888523
| 0.003871
|
P08183,P28070,Q99436,O00231,O43242,P49720,P33527,P20618,Q15008,P40855,Q9UL46,P05198,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
32,225,164,251,533,230,75,202,499,396,147,490,436,56,408,373,54
|
251,1266,2221,1226,533,1728,1961,1640,490,32,756,814,202,1059,1532,1158,1305,1199,225,373,54,1490,75,1872,396,1240,1093,230,56,557,994,1699,408,436,845,1279,884,821,695,2215,499,965,164,1177,1717,681,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.4346601796282852,-0.65444091817572,-0.3743308591385381,0.6047569844332618,2.908601987092757,0.3013170110599651,0.25201882658425456,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.2567482190180186,2.199400481282764,-0.5585543448403263,0.7356968204452725,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,-0.4043641190777143,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,0.15115395482942545,1.4232989777185565,-0.006127331605984542,-0.4043641190777143,0.3977415176858454,1.5406396934742081,-0.06023936284890438
| 2,468
|
Metalloendopeptidase activity
| 8
| 13
| 2.885648
| 0.003906
|
Q10713,O75844,P42892,P52888,Q5JRX3,Q9BYT8,P22695,Q92905
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
257,36,39,12,272,250,59,263
|
345,1606,36,873,59,39,12,257,272,263,1746,250,2150
|
0.8200789823454424,-0.34455645734238355,2.868122282262257,0.20197116058474252,2.461011602486414,2.827005651000117,3.4332901983397086,1.0603817720347808,1.0216002256059087,1.0603817720347808,-0.4346601796282852,1.0795911798832665,-0.8202718560579666
| 2,468
|
Steroid binding
| 8
| 19
| 2.878616
| 0.003994
|
P21796,P45880,P30536,P04062,O95772,Q14108,Q9BZF1,O15173
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
4,7,73,236,51,84,264,126
|
570,977,126,1961,51,236,981,1965,4,1797,2118,73,255,1534,7,84,830,2300,264
|
0.49139101679695213,0.1254502957539166,1.6535024833174539,-0.65444091817572,2.5544363806012425,1.117653769245169,0.1254502957539166,-0.65444091817572,3.838410894509741,-0.4960569056469889,-0.8202718560579666,2.238325990048142,1.0603817720347808,-0.2857688748733796,3.6667004853346468,2.119881427808456,0.25201882658425456,-1.1768795353111265,1.0603817720347808
| 2,468
|
Regulation of autophagy
| 24
| 76
| 2.876596
| 0.00402
|
P21796,Q96EB6,P38606,O15269,P07602,Q9UNH7,O75844,P40763,O00429,Q9Y487,P19474,O75436,P09429,P49841,P30536,Q93050,P10619,Q8IYI6,Q08379,Q15042,Q9UPT5,P04062,Q8IXJ6,Q9NZ45
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,398,524,153,31,428,36,416,412,181,50,431,319,327,73,76,81,211,471,233,502,236,109,115
|
1919,412,977,153,1440,2086,431,36,1192,236,2027,1758,1570,2157,1644,31,1153,2116,319,522,81,2210,811,1155,50,1303,914,2171,4,1198,73,524,416,1614,2035,2124,327,993,1737,1702,2097,1352,601,766,820,471,617,1135,1167,233,856,1071,109,211,2229,1460,76,398,1667,1713,1986,1178,727,1396,804,1078,1558,115,628,1600,1117,428,502,569,1403,181
|
-0.6221873063453945,0.692646228876154,0.1254502957539166,1.4909169970454357,-0.22797146657486117,-0.7864806683003362,0.6709000913867084,2.868122282262257,-0.033074608598505244,1.117653769245169,-0.7198459356446938,-0.46522306940850683,-0.3150370549937861,-0.8543859267849101,-0.3743308591385381,2.908601987092757,-0.006127331605984542,-0.8202718560579666,0.9022559500015589,0.5598892765754294,2.1599235408173723,-0.958720173237647,0.25201882658425456,-0.006127331605984542,2.5658905492788504,-0.11523365842189977,0.17666003360338126,-0.8888282886905626,3.838410894509741,-0.033074608598505244,2.238325990048142,0.5598892765754294,0.692646228876154,-0.34455645734238355,-0.7198459356446938,-0.8202718560579666,0.8819129546814536,0.1254502957539166,-0.4346601796282852,-0.4043641190777143,-0.7864806683003362,-0.1430695347463049,0.4682311897943023,0.3013170110599651,0.25201882658425456,0.6269572845849924,0.44490440798943937,0.020605480698360126,-0.006127331605984542,1.1365094929601929,0.22708991471684983,0.07343946733113242,1.8224978231489162,1.2107906833937936,-0.994181179090294,-0.22797146657486117,2.199400481282764,0.7356968204452725,-0.3743308591385381,-0.4043641190777143,-0.65444091817572,-0.006127331605984542,0.34988503514948976,-0.17113556168396907,0.27676037958362715,0.07343946733113242,-0.2857688748733796,1.807535106013106,0.44490440798943937,-0.3150370549937861,0.047126781746465576,0.692646228876154,0.6047569844332618,0.5143859578494419,-0.17113556168396907,1.3189165219976549
| 2,468
|
Regulation of runx3 expression and activity
| 13
| 35
| 2.872763
| 0.004069
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
protease
| 13
| 39
| 2.872668
| 0.00407
|
P28070,Q99436,O43242,P49720,Q9BT78,Q9UQ80,P20618,P49721,O75976,P60900,P50579,P28072,P28074
|
Functions
|
Panther Protein class
|
panther_protein_class
|
225,164,533,230,105,531,202,56,276,408,28,373,54
|
1266,1226,533,276,2154,756,202,1059,1532,1158,1305,1199,225,373,54,1872,2035,539,1240,1093,230,56,28,994,408,845,1279,884,695,1136,164,1177,105,1860,1748,940,1265,944,531
|
-0.08762466761145592,-0.06023936284890438,0.5372180454514659,1.0020254240102997,-0.8543859267849101,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.7198459356446938,0.5372180454514659,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,2.928608323075618,0.1254502957539166,0.7142445586094798,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.3739010819588171,0.020605480698360126,1.4232989777185565,-0.006127331605984542,1.8669254347810549,-0.5271658967301447,-0.4346601796282852,0.17666003360338126,-0.06023936284890438,0.17666003360338126,0.5598892765754294
| 2,468
|
Abnormal circulating cholesterol concentration
| 7
| 25
| 2.862448
| 0.004204
|
O75431,P37268,Q8N511,Q14739,Q13045,Q15392,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
191,131,6,139,248,61,31
|
191,1609,754,31,131,614,818,418,1451,1209,1619,248,1422,139,61,2258,619,284,6,1855,1179,1261,628,942,1297
|
1.2653360299982175,-0.34455645734238355,0.3013170110599651,2.908601987092757,1.6376421273678423,0.44490440798943937,0.25201882658425456,0.692646228876154,-0.22797146657486117,-0.033074608598505244,-0.34455645734238355,1.0795911798832665,-0.1994350717264357,1.6056618506283145,2.4130652487639477,-1.066163090613305,0.44490440798943937,0.9823261264765617,3.681490447648572,-0.5271658967301447,-0.006127331605984542,-0.06023936284890438,0.44490440798943937,0.17666003360338126,-0.08762466761145592
| 2,468
|
Receptor
| 6
| 20
| 2.836707
| 0.004558
|
A6NIH7,Q9UQB8,Q8WTV0,Q567V2,P39210,Q14108
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
1,34,38,17,176,84
|
1,836,1793,907,1412,1682,2156,1963,221,176,84,1138,17,38,621,1717,650,460,403,34
|
4.1239287394808555,0.22708991471684983,-0.4960569056469889,0.17666003360338126,-0.1994350717264357,-0.4043641190777143,-0.8543859267849101,-0.65444091817572,1.1738760097490326,1.3189165219976549,2.119881427808456,0.020605480698360126,3.202482497522664,2.857903513986415,0.44490440798943937,-0.4043641190777143,0.42140856532916043,0.6490043765907978,0.7356968204452725,2.8985408330958538
| 2,468
|
Protein maturation
| 16
| 56
| 2.828318
| 0.004679
|
P49366,O75503,Q10713,O75844,P42892,P67812,P62942,O00170,Q5JRX3,Q86UY6,Q92896,O75976,Q9BU89,P50579,Q15392,Q9NRN7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
95,66,257,36,39,173,238,207,272,178,94,276,91,28,61,184
|
207,684,1606,66,1412,36,276,1337,1271,2198,1829,1021,2324,1155,2449,2030,597,666,2035,539,39,95,1969,28,238,173,1619,257,1281,1420,1136,61,890,272,1706,178,2408,314,1665,94,724,1326,1463,400,1746,1910,1594,91,649,803,1396,938,1862,184,1263,2150
|
1.2107906833937936,0.3739010819588171,-0.34455645734238355,2.3395309528321633,-0.1994350717264357,2.868122282262257,1.0020254240102997,-0.1430695347463049,-0.08762466761145592,-0.9236044800386676,-0.5271658967301447,0.09954637705818221,-1.2910471139088535,-0.006127331605984542,-3.078970856737308,-0.7198459356446938,0.4682311897943023,0.3977415176858454,-0.7198459356446938,0.5372180454514659,2.827005651000117,1.9679892965036938,-0.65444091817572,2.928608323075618,1.117653769245169,1.3365673787376733,-0.34455645734238355,1.0603817720347808,-0.08762466761145592,-0.1994350717264357,0.020605480698360126,2.4130652487639477,0.20197116058474252,1.0216002256059087,-0.4043641190777143,1.3189165219976549,-1.7863055278776567,0.9224673008330843,-0.3743308591385381,1.9821392383520264,0.34988503514948976,-0.11523365842189977,-0.22797146657486117,0.7356968204452725,-0.4346601796282852,-0.590226648688484,-0.3150370549937861,2.03804423097585,0.42140856532916043,0.27676037958362715,-0.17113556168396907,0.17666003360338126,-0.5271658967301447,1.3011617275508496,-0.06023936284890438,-0.8202718560579666
| 2,468
|
Aurka activation by tpx2
| 9
| 26
| 2.816257
| 0.004859
|
Q13561,Q15154,P30153,O75935,P07437,P68371,Q9H6D7,Q15691,O95684
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
328,165,326,108,299,312,118,313,60
|
108,60,333,781,299,732,1155,326,760,556,1063,600,996,737,312,1622,328,1211,498,1213,165,313,1180,118,1670,2019
|
1.8373833245061917,2.43714387569957,0.8614368152158327,0.27676037958362715,0.9425484828699386,0.3256911134093675,-0.006127331605984542,0.8819129546814536,0.3013170110599651,0.5143859578494419,0.07343946733113242,0.4682311897943023,0.1254502957539166,0.3256911134093675,0.9224673008330843,-0.34455645734238355,0.8819129546814536,-0.033074608598505244,0.6047569844332618,-0.033074608598505244,1.4061522919477702,0.9224673008330843,-0.006127331605984542,1.7621766159448307,-0.3743308591385381,-0.6869921898793442
| 2,468
|
Organelle subcompartment
| 79
| 302
| 2.815569
| 0.004869
|
P24390,Q8N511,Q9BQE5,Q9Y282,P30519,Q86XL3,O75844,Q16850,O60725,Q9HD20,Q8N0U8,O95772,Q15392,Q9UBU6,Q14108,Q06136,Q8IV08,O00461,P07099,Q9NR09,Q96G23,Q5BJF2,P49257,Q8TB61,P43307,P37268,Q10472,Q14739,Q5H8A4,O15269,Q9NZ01,O95197,O43852,P63241,P67812,Q4J6C6,Q9Y4P3,P35613,O15121,P11717,Q15042,P04062,P53367,P62942,P16435,Q9BZF1,Q15629,Q10713,P35610,Q9Y5M8,O43493,O95470,Q15437,Q8N4V1,Q9P2W9,Q15904,O95864,O76062,P35606,Q9Y678,Q6NUM9,Q9HC07,Q15436,Q8TCT9,Q9NQC3,Q12893,Q9BT22,Q07065,Q9Y3Q3,Q9Y3B3,Q9UNN5,P31689,P10321,Q9BRR6,Q9NZ08,P55061,O75122,O00429,Q99720
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
5,6,20,21,27,35,36,43,44,47,49,51,61,65,84,98,100,101,104,110,114,116,119,128,132,131,138,139,142,153,161,168,170,171,173,174,190,214,218,221,233,236,237,238,245,264,259,257,255,268,266,269,279,286,288,284,282,289,291,295,305,307,304,314,331,350,354,349,368,367,381,374,384,401,427,419,414,412,443
|
1049,570,412,101,778,1438,750,683,1568,751,808,1407,218,488,978,153,1725,266,1793,1726,1409,170,505,952,44,1476,414,2402,2086,1961,1412,36,2056,289,1192,1523,168,2239,269,1996,51,282,1683,236,1479,1231,1195,781,104,1925,2116,1831,522,537,384,221,1376,245,434,1447,1833,1574,1379,1797,984,5,1646,2030,1237,2334,1491,2033,27,1966,374,1835,291,255,214,666,131,1534,1697,2316,1614,132,2123,734,881,493,691,119,762,692,818,1497,960,1309,1735,638,669,509,1736,237,1126,843,1537,419,1699,671,2068,2318,2004,1737,2304,1701,1738,1385,2399,2128,764,2130,238,1937,171,173,2008,847,1417,1209,1454,2435,998,98,349,527,471,1619,138,1314,257,1281,1874,350,1741,1131,923,1623,84,1456,1503,541,139,584,1214,1136,2136,1655,233,1979,797,698,61,304,279,259,2258,619,284,43,602,174,1390,116,142,2319,1847,1586,1457,1879,305,2228,1141,1069,700,1356,1071,1812,35,858,100,2328,49,286,6,2229,893,1882,2141,1663,1038,1853,1001,128,475,1983,1393,2340,314,1854,1460,529,1855,476,2166,2311,895,896,724,2230,1142,897,1257,1430,1550,114,624,1463,701,1289,442,647,1551,2410,969,443,1115,2274,1714,20,401,1291,2015,354,2330,1594,1717,1718,747,1364,1004,264,861,2249,863,1597,727,1886,1598,899,307,481,47,1145,1887,331,110,627,1723,161,427,482,1916,1821,288,748,942,65,681,2292,1560,1080,1786,1956,517,1563,2365,381,21,1298,2190,946,367,1473,368,190,268,1790,1889,295,1918,654
|
0.07343946733113242,0.49139101679695213,0.692646228876154,1.8961668597006474,0.27676037958362715,-0.22797146657486117,0.3013170110599651,0.3739010819588171,-0.3150370549937861,0.3013170110599651,0.25201882658425456,-0.1994350717264357,1.1738760097490326,0.6047569844332618,0.1254502957539166,1.4909169970454357,-0.4346601796282852,1.0410518943199942,-0.4960569056469889,-0.4346601796282852,-0.1994350717264357,1.3541153522401639,0.58240161346863,0.15115395482942545,2.666835954385971,-0.2567482190180186,0.692646228876154,-1.742458928246437,-0.7864806683003362,-0.65444091817572,-0.1994350717264357,2.868122282262257,-0.7530070814189461,0.9625009483378237,-0.033074608598505244,-0.2857688748733796,1.3715614817905903,-1.0299934512102915,1.0216002256059087,-0.6869921898793442,2.5544363806012425,0.9823261264765617,-0.4043641190777143,1.117653769245169,-0.2567482190180186,-0.06023936284890438,-0.033074608598505244,0.27676037958362715,1.8815833993429565,-0.6221873063453945,-0.8202718560579666,-0.5271658967301447,0.5598892765754294,0.5372180454514659,0.7570047251940325,1.1738760097490326,-0.17113556168396907,1.0795911798832665,0.6709000913867084,-0.22797146657486117,-0.5271658967301447,-0.3150370549937861,-0.17113556168396907,-0.4960569056469889,0.1254502957539166,3.8314985860427604,-0.3743308591385381,-0.7198459356446938,-0.06023936284890438,-1.3299025873109733,-0.2567482190180186,-0.7198459356446938,2.928608323075618,-0.65444091817572,0.7781699552447922,-0.5271658967301447,0.9625009483378237,1.0603817720347808,1.192389231232484,0.3977415176858454,1.6376421273678423,-0.2857688748733796,-0.4043641190777143,-1.2525962685132521,-0.34455645734238355,1.6376421273678423,-0.8202718560579666,0.3256911134093675,0.20197116058474252,0.6047569844332618,0.3739010819588171,1.7468979457042964,0.3013170110599651,0.3739010819588171,0.25201882658425456,-0.2567482190180186,0.15115395482942545,-0.11523365842189977,-0.4346601796282852,0.42140856532916043,0.3977415176858454,0.58240161346863,-0.4346601796282852,1.117653769245169,0.020605480698360126,0.22708991471684983,-0.2857688748733796,0.692646228876154,-0.4043641190777143,0.3977415176858454,-0.7530070814189461,-1.2525962685132521,-0.6869921898793442,-0.4346601796282852,-1.214542773220608,-0.4043641190777143,-0.4346601796282852,-0.17113556168396907,-1.6562527119273847,-0.8202718560579666,0.3013170110599651,-0.8202718560579666,1.117653769245169,-0.6221873063453945,1.3541153522401639,1.3365673787376733,-0.6869921898793442,0.22708991471684983,-0.1994350717264357,-0.033074608598505244,-0.22797146657486117,-2.3553677588654476,0.1254502957539166,1.9251128862095315,0.8200789823454424,0.5598892765754294,0.6269572845849924,-0.34455645734238355,1.6056618506283145,-0.11523365842189977,1.0603817720347808,-0.08762466761145592,-0.5585543448403263,0.8200789823454424,-0.4346601796282852,0.020605480698360126,0.17666003360338126,-0.34455645734238355,2.119881427808456,-0.22797146657486117,-0.2567482190180186,0.5372180454514659,1.6056618506283145,0.49139101679695213,-0.033074608598505244,0.020605480698360126,-0.8202718560579666,-0.3743308591385381,1.1365094929601929,-0.65444091817572,0.27676037958362715,0.3739010819588171,2.4130652487639477,0.9425484828699386,1.0020254240102997,1.0603817720347808,-1.066163090613305,0.44490440798943937,0.9823261264765617,2.7427903084146905,0.4682311897943023,1.3365673787376733,-0.17113556168396907,1.7924944732535362,1.5895402794086952,-1.2525962685132521,-0.5271658967301447,-0.3150370549937861,-0.22797146657486117,-0.5585543448403263,0.9425484828699386,-0.994181179090294,0.020605480698360126,0.07343946733113242,0.3739010819588171,-0.1430695347463049,0.07343946733113242,-0.4960569056469889,2.8783012459093062,0.22708991471684983,1.9106764725104468,-1.2910471139088535,2.5886536324101614,0.9823261264765617,3.681490447648572,-0.994181179090294,0.20197116058474252,-0.5585543448403263,-0.8202718560579666,-0.3743308591385381,0.09954637705818221,-0.5271658967301447,0.1254502957539166,1.6535024833174539,0.6269572845849924,-0.65444091817572,-0.17113556168396907,-1.3299025873109733,0.9224673008330843,-0.5271658967301447,-0.22797146657486117,0.5598892765754294,-0.5271658967301447,0.6269572845849924,-0.8543859267849101,-1.214542773220608,0.20197116058474252,0.20197116058474252,0.34988503514948976,-0.994181179090294,0.020605480698360126,0.20197116058474252,-0.06023936284890438,-0.1994350717264357,-0.2857688748733796,1.807535106013106,0.44490440798943937,-0.22797146657486117,0.3739010819588171,-0.08762466761145592,0.6709000913867084,0.42140856532916043,-0.2857688748733796,-1.7863055278776567,0.15115395482942545,0.6709000913867084,0.047126781746465576,-1.1026963504909864,-0.4043641190777143,3.139012561494263,0.7356968204452725,-0.08762466761145592,-0.6869921898793442,0.8200789823454424,-1.2910471139088535,-0.3150370549937861,-0.4043641190777143,-0.4043641190777143,0.3256911134093675,-0.1430695347463049,0.1254502957539166,1.0603817720347808,0.22708991471684983,-1.0299934512102915,0.22708991471684983,-0.3150370549937861,0.34988503514948976,-0.5585543448403263,-0.3150370549937861,0.20197116058474252,0.9425484828699386,0.6269572845849924,2.6224404188956902,0.020605480698360126,-0.5585543448403263,0.8819129546814536,1.8224978231489162,0.44490440798943937,-0.4043641190777143,1.457299817470005,0.692646228876154,0.6269572845849924,-0.590226648688484,-0.4960569056469889,0.9823261264765617,0.3256911134093675,0.17666003360338126,2.351924388044598,0.3977415176858454,-1.139599641176551,-0.2857688748733796,0.07343946733113242,-0.46522306940850683,-0.6221873063453945,0.58240161346863,-0.2857688748733796,-1.4088574939002534,0.7781699552447922,3.129814463490708,-0.08762466761145592,-0.8888282886905626,0.17666003360338126,0.7991941651751763,-0.22797146657486117,0.7991941651751763,1.2833019254548965,1.0410518943199942,-0.46522306940850683,-0.5585543448403263,0.9625009483378237,-0.590226648688484,0.42140856532916043
| 2,468
|
Anchoring of the basal body to the plasma membrane
| 9
| 27
| 2.804728
| 0.005036
|
Q13561,Q15154,P30153,O75935,P07437,P68371,Q9H6D7,Q15691,O95684
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
328,165,326,108,299,312,118,313,60
|
108,60,333,781,299,732,1155,326,760,556,1737,1063,600,996,737,312,1622,328,1211,498,1213,641,165,313,1180,118,1670
|
1.8373833245061917,2.43714387569957,0.8614368152158327,0.27676037958362715,0.9425484828699386,0.3256911134093675,-0.006127331605984542,0.8819129546814536,0.3013170110599651,0.5143859578494419,-0.4346601796282852,0.07343946733113242,0.4682311897943023,0.1254502957539166,0.3256911134093675,0.9224673008330843,-0.34455645734238355,0.8819129546814536,-0.033074608598505244,0.6047569844332618,-0.033074608598505244,0.42140856532916043,1.4061522919477702,0.9224673008330843,-0.006127331605984542,1.7621766159448307,-0.3743308591385381
| 2,468
|
Protein targeting
| 32
| 89
| 2.797268
| 0.005154
|
Q15629,Q99595,P43307,Q10713,O43615,Q9Y5M8,Q5JRX3,P40855,Q9H270,P55786,Q9NS69,O14737,O60725,Q7L5D6,O95831,P31946,Q16543,Q9UHB9,P09132,Q9Y2T2,Q3ZCQ8,Q8N4H5,P30536,O00170,O76094,Q14108,Q00535,P27348,O14925,O14964,P49257,P46379
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
259,2,132,257,503,268,272,396,274,23,29,413,44,562,298,555,585,462,192,332,456,198,73,207,573,84,601,346,485,487,119,123
|
1791,207,835,1119,413,485,487,503,1637,657,44,907,1606,573,1477,837,1339,298,1019,732,1925,192,2324,1445,1303,2059,346,1380,73,1493,555,1090,1930,396,132,123,119,762,2124,1934,1735,23,2068,2318,1206,2399,600,996,1739,1029,1247,601,257,1650,84,1136,1655,1283,259,1506,585,456,1105,272,562,1848,857,1285,198,2409,969,1630,1178,2,274,1396,2017,29,866,1560,462,903,1989,651,332,1403,1404,1372,268
|
-0.4960569056469889,1.2107906833937936,0.22708991471684983,0.020605480698360126,0.692646228876154,0.6047569844332618,0.6047569844332618,0.58240161346863,-0.3743308591385381,0.3977415176858454,2.666835954385971,0.17666003360338126,-0.34455645734238355,0.49139101679695213,-0.2567482190180186,0.22708991471684983,-0.1430695347463049,0.9425484828699386,0.09954637705818221,0.3256911134093675,-0.6221873063453945,1.2653360299982175,-1.2910471139088535,-0.22797146657486117,-0.11523365842189977,-0.7530070814189461,0.8200789823454424,-0.17113556168396907,2.238325990048142,-0.2567482190180186,0.5143859578494419,0.047126781746465576,-0.6221873063453945,0.7356968204452725,1.6376421273678423,1.6692773995529553,1.7468979457042964,0.3013170110599651,-0.8202718560579666,-0.6221873063453945,-0.4346601796282852,3.0739178449056257,-0.7530070814189461,-1.2525962685132521,-0.033074608598505244,-1.6562527119273847,0.4682311897943023,0.1254502957539166,-0.4346601796282852,0.09954637705818221,-0.06023936284890438,0.4682311897943023,1.0603817720347808,-0.3743308591385381,2.119881427808456,0.020605480698360126,-0.3743308591385381,-0.08762466761145592,1.0603817720347808,-0.2567482190180186,0.49139101679695213,0.6490043765907978,0.047126781746465576,1.0216002256059087,0.5143859578494419,-0.5271658967301447,0.22708991471684983,-0.08762466761145592,1.2472629393969026,-1.7863055278776567,0.15115395482942545,-0.34455645734238355,-0.006127331605984542,4.0993803881071775,1.0216002256059087,-0.17113556168396907,-0.6869921898793442,2.928608323075618,0.22708991471684983,-0.2857688748733796,0.6490043765907978,0.20197116058474252,-0.65444091817572,0.42140856532916043,0.8819129546814536,-0.17113556168396907,-0.17113556168396907,-0.1430695347463049,1.0410518943199942
| 2,468
|
Recruitment of mitotic centrosome proteins and complexes
| 9
| 27
| 2.792245
| 0.005234
|
Q13561,Q15154,P30153,O75935,P07437,P68371,Q9H6D7,Q15691,O95684
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
328,165,326,108,299,312,118,313,60
|
108,60,333,781,299,732,1155,326,760,556,1063,600,996,737,312,1622,328,1211,498,1213,165,313,2078,1362,1180,118,1670
|
1.8373833245061917,2.43714387569957,0.8614368152158327,0.27676037958362715,0.9425484828699386,0.3256911134093675,-0.006127331605984542,0.8819129546814536,0.3013170110599651,0.5143859578494419,0.07343946733113242,0.4682311897943023,0.1254502957539166,0.3256911134093675,0.9224673008330843,-0.34455645734238355,0.8819129546814536,-0.033074608598505244,0.6047569844332618,-0.033074608598505244,1.4061522919477702,0.9224673008330843,-0.7530070814189461,-0.1430695347463049,-0.006127331605984542,1.7621766159448307,-0.3743308591385381
| 2,468
|
Intra golgi and retrograde golgi to er traffic
| 25
| 77
| 2.783393
| 0.005379
|
P24390,Q10472,O43493,Q9P2W9,P35606,Q9Y678,Q12756,P68371,Q9BVA1,Q13561,Q8TD16,P04350,Q8TBA6,Q92538,Q9UJW0,P11717,Q9Y3Q3,Q9Y3B3,O00461,Q14203,Q15042,P52732,Q9NSK0,O75935,P62820
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
5,138,266,288,291,295,437,312,458,328,206,333,475,476,355,221,368,367,101,498,233,494,107,108,359
|
1891,101,750,683,1681,1725,266,1726,1053,2086,108,1268,908,333,221,1528,1574,5,815,291,2316,556,2123,1203,817,881,692,494,1243,1736,1126,843,1971,1063,764,359,737,312,2097,1312,792,1619,138,437,1131,923,1622,328,618,498,1213,1908,233,2047,698,1110,475,206,476,1327,933,501,726,458,747,1365,1597,727,1145,107,288,1786,355,367,368,295,1082
|
-0.590226648688484,1.8961668597006474,0.3013170110599651,0.3739010819588171,-0.4043641190777143,-0.4346601796282852,1.0410518943199942,-0.4346601796282852,0.07343946733113242,-0.7864806683003362,1.8373833245061917,-0.08762466761145592,0.17666003360338126,0.8614368152158327,1.1738760097490326,-0.2857688748733796,-0.3150370549937861,3.8314985860427604,0.25201882658425456,0.9625009483378237,-1.2525962685132521,0.5143859578494419,-0.8202718560579666,-0.033074608598505244,0.25201882658425456,0.20197116058474252,0.3739010819588171,0.6047569844332618,-0.06023936284890438,-0.4346601796282852,0.020605480698360126,0.22708991471684983,-0.65444091817572,0.07343946733113242,0.3013170110599651,0.7991941651751763,0.3256911134093675,0.9224673008330843,-0.7864806683003362,-0.11523365842189977,0.27676037958362715,-0.34455645734238355,1.6056618506283145,0.6709000913867084,0.020605480698360126,0.17666003360338126,-0.34455645734238355,0.8819129546814536,0.44490440798943937,0.6047569844332618,-0.033074608598505244,-0.590226648688484,1.1365094929601929,-0.7198459356446938,0.3739010819588171,0.047126781746465576,0.6269572845849924,1.2290815354843998,0.6269572845849924,-0.11523365842189977,0.17666003360338126,0.6047569844332618,0.34988503514948976,0.6490043765907978,0.3256911134093675,-0.1430695347463049,-0.3150370549937861,0.34988503514948976,0.020605480698360126,1.8521923010037062,0.9823261264765617,-0.46522306940850683,0.8200789823454424,0.7991941651751763,0.7991941651751763,0.9625009483378237,0.07343946733113242
| 2,468
|
Organic anion transport
| 16
| 44
| 2.78238
| 0.005396
|
Q8TB61,P21359,Q14728,P53985,Q7L0J3,Q9UBX3,Q15042,P33527,Q9Y289,Q9H2D1,Q99808,Q9Y619,P11166,P14174,P04920,P07602
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,415,453,40,41,199,233,75,518,14,342,125,491,277,187,31
|
534,1054,1411,2056,1121,1757,187,2157,1963,31,1481,491,811,1612,277,415,1490,75,2066,40,1245,1803,453,1655,233,1544,2103,1141,41,128,342,1715,1778,14,1366,1433,1633,834,628,199,1080,1297,518,125
|
0.5372180454514659,0.07343946733113242,-0.1994350717264357,-0.7530070814189461,0.020605480698360126,-0.46522306940850683,1.2833019254548965,-0.8543859267849101,-0.65444091817572,2.908601987092757,-0.2567482190180186,0.6047569844332618,0.25201882658425456,-0.34455645734238355,1.0020254240102997,0.692646228876154,-0.2567482190180186,2.199400481282764,-0.7530070814189461,2.827005651000117,-0.06023936284890438,-0.4960569056469889,0.6490043765907978,-0.3743308591385381,1.1365094929601929,-0.2857688748733796,-0.7864806683003362,0.020605480698360126,2.827005651000117,1.6535024833174539,0.8408260074769911,-0.4043641190777143,-0.46522306940850683,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,0.25201882658425456,0.44490440798943937,1.2472629393969026,0.07343946733113242,-0.08762466761145592,0.58240161346863,1.6692773995529553
| 2,468
|
The role of gtse1 in g2 m progression after g2 checkpoint
| 18
| 47
| 2.773462
| 0.005546
|
Q9BVA1,P28070,Q99436,O43242,O00231,P49720,P20618,P04350,Q15008,Q9UL46,P51665,P61289,P49721,P60900,Q15691,P68371,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
458,225,164,533,251,230,202,333,499,147,557,436,56,408,313,312,373,54
|
251,1266,2221,1226,533,1640,333,1758,781,732,956,1057,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,312,821,695,618,2215,499,313,164,1177,726,458,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.8614368152158327,-0.46522306940850683,0.27676037958362715,0.3256911134093675,0.15115395482942545,0.07343946733113242,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.9224673008330843,0.25201882658425456,0.3739010819588171,0.44490440798943937,-0.958720173237647,0.6047569844332618,0.9224673008330843,1.4232989777185565,-0.006127331605984542,0.34988503514948976,0.6490043765907978,1.5406396934742081,-0.06023936284890438
| 2,468
|
Regulation of hormone levels
| 11
| 49
| 2.764083
| 0.005708
|
O60678,O75844,Q9HB40,O94788,P42892,P53985,Q6NUM9,P30536,O95470,P07858,P16435
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,36,68,102,39,40,305,73,269,80,245
|
2113,2023,1150,952,195,1412,36,102,269,1121,1730,1757,981,80,1232,873,1832,245,300,1797,73,1966,1275,39,2092,1125,669,40,359,451,1874,1130,769,1139,824,1390,305,893,1662,2181,1983,724,1463,1395,1986,2185,68,942,428
|
-0.8202718560579666,-0.7198459356446938,-0.006127331605984542,0.15115395482942545,1.2472629393969026,-0.1994350717264357,2.868122282262257,1.8961668597006474,1.0216002256059087,0.020605480698360126,-0.4346601796282852,-0.46522306940850683,0.1254502957539166,2.1599235408173723,-0.06023936284890438,0.20197116058474252,-0.5271658967301447,1.0795911798832665,0.9425484828699386,-0.4960569056469889,2.238325990048142,-0.65444091817572,-0.08762466761145592,2.827005651000117,-0.7864806683003362,0.020605480698360126,0.3977415176858454,2.827005651000117,0.7991941651751763,0.6490043765907978,-0.5585543448403263,0.020605480698360126,0.3013170110599651,0.020605480698360126,0.25201882658425456,-0.17113556168396907,0.9425484828699386,0.20197116058474252,-0.3743308591385381,-0.8888282886905626,-0.65444091817572,0.34988503514948976,-0.22797146657486117,-0.17113556168396907,-0.65444091817572,-0.8888282886905626,2.3270814179529142,0.17666003360338126,0.692646228876154
| 2,468
|
Sphingolipid metabolism
| 8
| 11
| 2.748839
| 0.005981
|
Q06136,P04062,O95470,P16278,P06280,O15269,O15121,Q16739
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
98,236,269,18,339,153,218,92
|
218,153,1637,269,236,339,18,98,361,92,1723
|
1.1738760097490326,1.4909169970454357,-0.3743308591385381,1.0216002256059087,1.117653769245169,0.8408260074769911,3.1754755052007098,1.9251128862095315,0.7991941651751763,2.024171009993822,-0.4043641190777143
| 2,468
|
Alcohol binding
| 6
| 13
| 2.72508
| 0.006429
|
P21796,P45880,P30536,O95772,Q14108,Q9BZF1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
4,7,73,51,84,264
|
1568,977,1961,51,1965,4,2118,1999,73,255,7,84,264
|
-0.3150370549937861,0.1254502957539166,-0.65444091817572,2.5544363806012425,-0.65444091817572,3.838410894509741,-0.8202718560579666,-0.6869921898793442,2.238325990048142,1.0603817720347808,3.6667004853346468,2.119881427808456,1.0603817720347808
| 2,468
|
Cdt1 association with the cdc6 orc origin complex
| 14
| 39
| 2.724503
| 0.00644
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,Q9Y619,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,373,147,436,56,408,125,54
|
251,1266,2221,1226,533,1228,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,696,2215,499,164,1177,147,1265,125
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.06023936284890438,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438,1.6692773995529553
| 2,468
|
Hyperlipidemia
| 9
| 26
| 2.72362
| 0.006457
|
Q13045,P28070,O75844,O95470,O43707,P49257,P22830,P23786,O75431
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
248,225,36,269,297,119,150,26,191
|
1189,297,191,36,269,1609,339,754,150,26,225,1344,759,119,818,1538,248,1422,2216,1855,1950,2230,1179,1297,652,1405
|
-0.033074608598505244,0.9425484828699386,1.2653360299982175,2.868122282262257,1.0216002256059087,-0.34455645734238355,0.8408260074769911,0.3013170110599651,1.5075840575864408,2.9583317443973955,1.1552498319919475,-0.1430695347463049,0.3013170110599651,1.7468979457042964,0.25201882658425456,-0.2857688748733796,1.0795911798832665,-0.1994350717264357,-0.958720173237647,-0.5271658967301447,-0.6221873063453945,-0.994181179090294,-0.006127331605984542,-0.08762466761145592,0.42140856532916043,-0.17113556168396907
| 2,468
|
Metalloprotease
| 11
| 22
| 2.715832
| 0.006611
|
O43847,O75844,P42892,Q9BYT8,P52888,Q5JRX3,Q92905,P55786,O75976,Q9UIQ6,P09960
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
345,36,39,250,12,272,263,23,276,58,283
|
2221,345,1606,36,276,283,2416,873,39,12,23,272,1356,263,1746,250,1007,1862,940,427,58,2150
|
-0.994181179090294,0.8200789823454424,-0.34455645734238355,2.868122282262257,1.0020254240102997,0.9823261264765617,-1.9209411773807756,0.20197116058474252,2.827005651000117,3.4332901983397086,3.0739178449056257,1.0216002256059087,-0.1430695347463049,1.0603817720347808,-0.4346601796282852,1.0795911798832665,0.1254502957539166,-0.5271658967301447,0.17666003360338126,0.692646228876154,2.4728673792906726,-0.8202718560579666
| 2,468
|
Ub specific processing proteases
| 22
| 61
| 2.704403
| 0.006843
|
Q9Y3E5,P21796,O00231,P45880,Q96FW1,Q9UL46,Q9Y277,P60900,Q86UV5,Q99436,O43242,P61289,P49721,P28074,P20618,Q9UPU5,P28070,P49720,Q15008,O14964,P28072,Q93009
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
391,4,251,7,399,147,275,408,410,164,533,436,56,54,202,212,225,230,499,487,373,513
|
251,1266,2221,1226,487,533,1638,1640,1477,1758,873,756,202,4,1059,1532,1158,1305,1199,225,373,54,1872,1240,7,1161,1093,230,56,557,1061,994,408,436,845,1279,884,821,695,1503,1167,2215,499,1283,410,1588,2456,896,828,513,399,164,1177,1186,147,1265,212,2148,275,391,2278
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.6047569844332618,0.5372180454514659,-0.3743308591385381,-0.3743308591385381,-0.2567482190180186,-0.46522306940850683,0.20197116058474252,0.3013170110599651,1.2290815354843998,3.838410894509741,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,3.6667004853346468,-0.006127331605984542,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.07343946733113242,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.2567482190180186,-0.006127331605984542,-0.958720173237647,0.6047569844332618,-0.08762466761145592,0.7142445586094798,-0.3150370549937861,-3.3908979163224866,0.20197116058474252,0.25201882658425456,0.58240161346863,0.7356968204452725,1.4232989777185565,-0.006127331605984542,-0.006127331605984542,1.5406396934742081,-0.06023936284890438,1.2107906833937936,-0.8202718560579666,1.0216002256059087,0.7570047251940325,-1.1026963504909864
| 2,468
|
Cellular response to chemical stress
| 23
| 67
| 2.696954
| 0.006998
|
O00231,P09601,Q9UL46,P60900,P30519,Q99436,O43242,P40763,P09669,Q8TCT9,P49721,P61289,P28074,P00403,P33527,P20618,Q86X55,P63208,P28070,P49720,Q15008,Q9BZK7,P28072
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
251,522,147,408,27,164,533,416,175,314,56,436,54,324,75,202,210,470,225,230,499,265,373
|
251,1266,2151,2221,1226,533,1299,1640,1641,1020,324,1086,522,175,1572,1154,1687,756,1303,202,2255,1059,1532,1158,1305,1199,225,373,54,1694,733,2060,27,1762,75,1872,416,1578,1240,1093,230,56,557,1837,994,408,436,845,1279,884,470,821,695,2269,793,2215,499,1423,210,314,1463,1395,164,1177,265,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.8543859267849101,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.11523365842189977,-0.3743308591385381,-0.3743308591385381,0.09954637705818221,0.8819129546814536,0.047126781746465576,0.5598892765754294,1.3189165219976549,-0.3150370549937861,-0.006127331605984542,-0.4043641190777143,0.3013170110599651,-0.11523365842189977,1.2290815354843998,-1.066163090613305,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.4043641190777143,0.3256911134093675,-0.7530070814189461,2.928608323075618,-0.46522306940850683,2.199400481282764,-0.5585543448403263,0.692646228876154,-0.3150370549937861,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,-0.5271658967301447,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,0.27676037958362715,-0.958720173237647,0.6047569844332618,-0.1994350717264357,1.2107906833937936,0.9224673008330843,-0.22797146657486117,-0.17113556168396907,1.4232989777185565,-0.006127331605984542,1.0603817720347808,1.5406396934742081,-0.06023936284890438
| 2,468
|
Muscle stiffness
| 9
| 16
| 2.693655
| 0.007067
|
Q8NBU5,P53985,P52732,P06753,Q12756,P11166,P23786,Q15392,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
262,40,494,447,437,491,26,61,31
|
1270,447,31,491,26,1647,494,40,1384,437,61,1548,262,628,552,1405
|
-0.08762466761145592,0.6490043765907978,2.908601987092757,0.6047569844332618,2.9583317443973955,-0.3743308591385381,0.6047569844332618,2.827005651000117,-0.17113556168396907,0.6709000913867084,2.4130652487639477,-0.2857688748733796,1.0603817720347808,0.44490440798943937,0.5372180454514659,-0.17113556168396907
| 2,468
|
Metabolism of polyamines
| 14
| 39
| 2.693125
| 0.007079
|
P28070,Q99436,O00231,O43242,P49720,P20618,Q15008,P19623,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,251,533,230,202,499,393,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,393,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,1026,994,408,436,845,1279,884,821,695,2215,499,164,1177,1366,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,0.7356968204452725,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.09954637705818221,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,-0.1430695347463049,1.5406396934742081,-0.06023936284890438
| 2,468
|
Interleukin 1 family signaling
| 17
| 43
| 2.691783
| 0.007107
|
P09429,P28070,Q99436,O43242,O00231,P49720,Q06124,P40763,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
319,225,164,533,251,230,451,416,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,319,756,202,1059,1532,1158,1305,1199,225,373,54,1872,416,1240,1093,230,56,557,994,408,1350,436,845,1279,884,470,1542,451,821,695,2269,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.9022559500015589,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,0.692646228876154,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,-0.1430695347463049,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,-0.2857688748733796,0.6490043765907978,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Hydrolase activity hydrolyzing o glycosyl compounds
| 7
| 16
| 2.691116
| 0.007121
|
Q9NUJ1,P04062,P06865,P16278,Q9BTY2,O60502,P04066
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
72,236,209,18,152,25,310
|
729,25,236,310,339,209,536,1234,18,609,759,693,1623,1767,152,72
|
0.3256911134093675,2.9583317443973955,1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,0.5372180454514659,-0.06023936284890438,3.1754755052007098,0.44490440798943937,0.3013170110599651,0.3739010819588171,-0.34455645734238355,-0.46522306940850683,1.5075840575864408,2.2511809259257114
| 2,468
|
Proteasome
| 13
| 35
| 2.689269
| 0.007161
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Vascular transport
| 7
| 12
| 2.657991
| 0.007861
|
P08183,P53985,P33527,P23634,Q99808,P11166,P02786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,40,75,394,342,491,432
|
432,32,491,394,75,40,1245,1544,1141,342,1366,518
|
0.6709000913867084,2.908601987092757,0.6047569844332618,0.7356968204452725,2.199400481282764,2.827005651000117,-0.06023936284890438,-0.2857688748733796,0.020605480698360126,0.8408260074769911,-0.1430695347463049,0.58240161346863
| 2,468
|
Degradation of beta catenin by the destruction complex
| 17
| 46
| 2.657963
| 0.007861
|
P28070,Q99436,O43242,O00231,P49720,P49841,P30154,P30153,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,327,450,326,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,326,450,1533,1872,1240,1093,1124,230,56,327,557,994,1450,408,436,845,1279,884,470,821,695,676,2269,925,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,0.8819129546814536,0.6490043765907978,-0.2857688748733796,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,0.020605480698360126,1.1365094929601929,2.4964247239663777,0.8819129546814536,0.5143859578494419,0.1254502957539166,-0.22797146657486117,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,0.3977415176858454,-1.1026963504909864,0.17666003360338126,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
metalloprotease
| 12
| 22
| 2.657816
| 0.007865
|
Q9NZ08,O43847,Q10713,O75844,P42892,Q9BYT8,P52888,Q5JRX3,Q8IYS1,P55786,Q9UIQ6,P22695
|
Functions
|
Panther Protein class
|
panther_protein_class
|
427,345,257,36,39,250,12,272,440,23,58,59
|
345,1606,36,432,2416,873,59,2334,663,39,12,23,257,272,1356,440,1746,250,1862,427,58,2150
|
0.8200789823454424,-0.34455645734238355,2.868122282262257,0.6709000913867084,-1.9209411773807756,0.20197116058474252,2.461011602486414,-1.3299025873109733,0.3977415176858454,2.827005651000117,3.4332901983397086,3.0739178449056257,1.0603817720347808,1.0216002256059087,-0.1430695347463049,0.6709000913867084,-0.4346601796282852,1.0795911798832665,-0.5271658967301447,0.692646228876154,2.4728673792906726,-0.8202718560579666
| 2,468
|
Glycoside hydrolase superfamily [IPR017853]
| 6
| 14
| 2.653865
| 0.007958
|
P04062,P06865,P16278,Q9BTY2,O60502,P04066
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
236,209,18,152,25,310
|
25,236,310,339,209,536,1481,1234,18,759,693,1767,152,1364
|
2.9583317443973955,1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,0.5372180454514659,-0.2567482190180186,-0.06023936284890438,3.1754755052007098,0.3013170110599651,0.3739010819588171,-0.46522306940850683,1.5075840575864408,-0.1430695347463049
| 2,468
|
Sphingolipid biosynthetic process
| 8
| 14
| 2.652289
| 0.007995
|
Q06136,P04062,O95470,Q96G23,Q99805,O15269,O15121,Q16739
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,236,269,114,180,153,218,92
|
218,153,269,236,1797,98,361,92,1105,114,180,1723,482,1916
|
1.1738760097490326,1.4909169970454357,1.0216002256059087,1.117653769245169,-0.4960569056469889,1.9251128862095315,0.7991941651751763,2.024171009993822,0.047126781746465576,1.807535106013106,1.3189165219976549,-0.4043641190777143,0.6269572845849924,-0.590226648688484
| 2,468
|
Synthesis of dna
| 30
| 69
| 2.650397
| 0.00804
|
Q16763,O00231,P25205,Q07864,Q9UL46,P33991,P60900,Q99436,O43242,Q9Y2S7,Q9H1A4,P51665,P61289,P49736,P49721,Q9UJX2,P28074,Q13416,Q9BRT9,P20618,P35250,Q14566,P63208,P33993,P24941,P28070,P49720,Q15008,P28072,Q9Y619
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
260,251,633,526,147,405,408,164,533,569,703,557,436,435,56,710,54,696,457,202,576,452,470,468,224,225,230,499,373,125
|
251,1266,2221,1226,533,1228,1640,1894,982,756,202,224,633,1059,1532,1158,1305,1022,1199,225,373,54,1344,1492,405,1060,468,1763,576,1734,1872,988,989,1898,1240,1093,917,230,56,435,557,994,408,436,845,1279,884,470,821,526,695,696,2269,452,2215,499,260,164,1177,457,703,1721,710,1013,774,147,1265,569,125
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.06023936284890438,-0.3743308591385381,-0.590226648688484,0.1254502957539166,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.42140856532916043,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,0.09954637705818221,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.1430695347463049,-0.2567482190180186,0.7142445586094798,0.07343946733113242,0.6269572845849924,-0.46522306940850683,0.49139101679695213,-0.4346601796282852,-0.5585543448403263,0.1254502957539166,0.1254502957539166,-0.590226648688484,-0.06023936284890438,0.047126781746465576,0.17666003360338126,1.1365094929601929,2.4964247239663777,0.6709000913867084,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.5598892765754294,0.3739010819588171,0.3739010819588171,-1.1026963504909864,0.6490043765907978,-0.958720173237647,0.6047569844332618,1.0603817720347808,1.4232989777185565,-0.006127331605984542,0.6490043765907978,0.3739010819588171,-0.4043641190777143,0.3739010819588171,0.1254502957539166,0.3013170110599651,1.5406396934742081,-0.06023936284890438,0.5143859578494419,1.6692773995529553
| 2,468
|
Regulation of ras by gaps
| 14
| 38
| 2.647048
| 0.00812
|
P28070,P21359,Q99436,O00231,O43242,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,415,164,251,533,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,202,415,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,793,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.692646228876154,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,0.27676037958362715,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
G1 s dna damage checkpoints
| 14
| 38
| 2.636299
| 0.008382
|
P24941,P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
224,225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,1758,756,202,224,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,-0.46522306940850683,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Cholesterol binding
| 6
| 11
| 2.627247
| 0.008608
|
P21796,P45880,P30536,O95772,Q14108,Q9BZF1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
4,7,73,51,84,264
|
977,1961,51,1965,4,2118,73,255,7,84,264
|
0.1254502957539166,-0.65444091817572,2.5544363806012425,-0.65444091817572,3.838410894509741,-0.8202718560579666,2.238325990048142,1.0603817720347808,3.6667004853346468,2.119881427808456,1.0603817720347808
| 2,468
|
Tapered finger
| 7
| 34
| 2.626276
| 0.008632
|
Q06136,P42892,Q96EK5,Q8NCH0,P27635,P23786,Q03164
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,39,135,85,83,26,157
|
1566,207,1920,952,26,1489,83,634,39,1276,2317,1126,2004,157,1974,98,437,1166,1583,1251,743,769,1285,800,85,529,828,135,1516,2343,1780,1184,519,1188
|
-0.3150370549937861,1.2107906833937936,-0.6221873063453945,0.15115395482942545,2.9583317443973955,-0.2567482190180186,2.119881427808456,0.42140856532916043,2.827005651000117,-0.08762466761145592,-1.2525962685132521,0.020605480698360126,-0.6869921898793442,1.4741558928304515,-0.65444091817572,1.9251128862095315,0.6709000913867084,-0.006127331605984542,-0.3150370549937861,-0.06023936284890438,0.3256911134093675,0.3013170110599651,-0.08762466761145592,0.27676037958362715,2.119881427808456,0.5598892765754294,0.25201882658425456,1.6216955230183503,-0.2567482190180186,-1.3299025873109733,-0.46522306940850683,-0.006127331605984542,0.58240161346863,-0.006127331605984542
| 2,468
|
Lytic vacuole organization
| 7
| 21
| 2.624379
| 0.008681
|
O75503,P11117,Q8N511,P04062,O14773,P50897,Q14108
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,229,6,236,141,112,84
|
835,141,66,1412,236,536,1234,229,1614,112,1934,693,1701,84,2203,6,1002,1550,1713,307,1917
|
0.22708991471684983,1.5895402794086952,2.3395309528321633,-0.1994350717264357,1.117653769245169,0.5372180454514659,-0.06023936284890438,1.1365094929601929,-0.34455645734238355,1.807535106013106,-0.6221873063453945,0.3739010819588171,-0.4043641190777143,2.119881427808456,-0.9236044800386676,3.681490447648572,0.1254502957539166,-0.2857688748733796,-0.4043641190777143,0.9425484828699386,-0.590226648688484
| 2,468
|
Golgi to er retrograde transport
| 21
| 65
| 2.623009
| 0.008716
|
P24390,Q10472,Q9P2W9,P35606,Q9Y678,Q12756,P68371,Q9BVA1,Q13561,Q8TD16,P04350,Q92538,Q9UJW0,Q14203,Q9Y3Q3,Q9Y3B3,P52732,Q15042,Q9NSK0,O75935,P62820
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
5,138,288,291,295,437,312,458,328,206,333,476,355,498,368,367,494,233,107,108,359
|
1891,750,1725,2086,108,1268,908,333,1528,1574,5,815,291,556,2123,1203,817,881,692,494,1243,1126,843,1971,1063,764,359,737,312,2097,1312,792,1619,138,437,1131,1622,328,618,498,1213,1908,233,2047,698,1110,206,476,1327,933,501,726,458,747,1365,1597,727,1145,107,288,355,367,368,295,1082
|
-0.590226648688484,0.3013170110599651,-0.4346601796282852,-0.7864806683003362,1.8373833245061917,-0.08762466761145592,0.17666003360338126,0.8614368152158327,-0.2857688748733796,-0.3150370549937861,3.8314985860427604,0.25201882658425456,0.9625009483378237,0.5143859578494419,-0.8202718560579666,-0.033074608598505244,0.25201882658425456,0.20197116058474252,0.3739010819588171,0.6047569844332618,-0.06023936284890438,0.020605480698360126,0.22708991471684983,-0.65444091817572,0.07343946733113242,0.3013170110599651,0.7991941651751763,0.3256911134093675,0.9224673008330843,-0.7864806683003362,-0.11523365842189977,0.27676037958362715,-0.34455645734238355,1.6056618506283145,0.6709000913867084,0.020605480698360126,-0.34455645734238355,0.8819129546814536,0.44490440798943937,0.6047569844332618,-0.033074608598505244,-0.590226648688484,1.1365094929601929,-0.7198459356446938,0.3739010819588171,0.047126781746465576,1.2290815354843998,0.6269572845849924,-0.11523365842189977,0.17666003360338126,0.6047569844332618,0.34988503514948976,0.6490043765907978,0.3256911134093675,-0.1430695347463049,-0.3150370549937861,0.34988503514948976,0.020605480698360126,1.8521923010037062,0.9823261264765617,0.8200789823454424,0.7991941651751763,0.7991941651751763,0.9625009483378237,0.07343946733113242
| 2,468
|
Negative regulation of notch4 signaling
| 14
| 39
| 2.614775
| 0.008929
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,1029,470,821,695,2269,499,164,1177,147,1265,869
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.09954637705818221,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438,0.22708991471684983
| 2,468
|
Cross presentation of soluble exogenous antigens endosomes
| 13
| 36
| 2.601264
| 0.009288
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Degradation of axin
| 13
| 36
| 2.601264
| 0.009288
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Regulation of pten stability and activity
| 13
| 37
| 2.594002
| 0.009487
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,1303,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,-0.11523365842189977,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand
| 15
| 28
| 2.590983
| 0.00957
|
Q15185,Q02790,Q9BVA1,Q13561,P63167,Q14203,P31948,Q13451,O75935,P04350,Q9BUF5,P31689,Q9UJW0,P68371,Q13885
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
542,740,458,328,737,498,635,581,108,333,726,374,355,312,618
|
108,333,732,956,1483,1445,1157,374,635,1203,817,1243,1063,737,312,740,1622,581,328,618,498,1213,542,1327,726,458,355,1082
|
1.8373833245061917,0.8614368152158327,0.3256911134093675,0.15115395482942545,-0.2567482190180186,-0.22797146657486117,-0.006127331605984542,0.7781699552447922,0.42140856532916043,-0.033074608598505244,0.25201882658425456,-0.06023936284890438,0.07343946733113242,0.3256911134093675,0.9224673008330843,0.3256911134093675,-0.34455645734238355,0.49139101679695213,0.8819129546814536,0.44490440798943937,0.6047569844332618,-0.033074608598505244,0.5372180454514659,-0.11523365842189977,0.34988503514948976,0.6490043765907978,0.8200789823454424,0.07343946733113242
| 2,468
|
Abnormal sacrum morphology
| 12
| 24
| 2.587803
| 0.009659
|
P49366,O96028,Q14739,Q5H8A4,P35250,P27635,P43034,P61978,Q9Y4P3,P04066,Q03164,P53701
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
95,535,139,142,576,83,556,599,190,310,157,96
|
1266,1828,1300,535,310,83,576,2000,556,95,96,599,996,1311,157,616,139,1137,142,1284,828,2054,1563,190
|
-0.08762466761145592,-0.5271658967301447,-0.11523365842189977,0.5372180454514659,0.9224673008330843,2.119881427808456,0.49139101679695213,-0.6869921898793442,0.5143859578494419,1.9679892965036938,1.9679892965036938,0.4682311897943023,0.1254502957539166,-0.11523365842189977,1.4741558928304515,0.44490440798943937,1.6056618506283145,0.020605480698360126,1.5895402794086952,-0.08762466761145592,0.25201882658425456,-0.7198459356446938,-0.2857688748733796,1.2833019254548965
| 2,468
|
Cellular hormone metabolic process
| 6
| 13
| 2.587171
| 0.009677
|
O60678,Q9HB40,O94788,P42892,P30536,O95470
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,68,102,39,73,269
|
195,102,269,1832,73,39,1125,1390,305,1662,1983,2185,68
|
1.2472629393969026,1.8961668597006474,1.0216002256059087,-0.5271658967301447,2.238325990048142,2.827005651000117,0.020605480698360126,-0.17113556168396907,0.9425484828699386,-0.3743308591385381,-0.65444091817572,-0.8888282886905626,2.3270814179529142
| 2,468
|
Regulation of hmox1 expression and activity
| 16
| 42
| 2.585062
| 0.009736
|
P28070,Q99436,O00231,O43242,P49720,P20618,Q15008,P09601,Q9UL46,P28072,P49721,Q8TCT9,P61289,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,251,533,230,202,499,522,147,373,56,314,436,408,470,54
|
251,1266,2221,1226,533,1640,522,756,1303,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,470,821,695,2269,793,2215,499,314,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.5598892765754294,0.3013170110599651,-0.11523365842189977,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,0.27676037958362715,-0.958720173237647,0.6047569844332618,0.9224673008330843,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Modified amino acid binding
| 7
| 17
| 2.580065
| 0.009878
|
O60678,Q8WTV0,P21266,O43813,P00374,Q14108,Q9BZF1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
195,38,254,201,79,84,264
|
201,195,79,1829,1965,319,1445,254,1531,667,1094,84,38,1115,1910,264,1866
|
1.2290815354843998,1.2472629393969026,2.1599235408173723,-0.5271658967301447,-0.65444091817572,0.9022559500015589,-0.22797146657486117,1.0603817720347808,-0.2857688748733796,0.3977415176858454,0.047126781746465576,2.119881427808456,2.857903513986415,0.047126781746465576,-0.590226648688484,1.0603817720347808,-0.5271658967301447
| 2,468
|
Transcriptional regulation by runx3
| 14
| 39
| 2.573026
| 0.010081
|
P25440,P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
466,225,164,533,251,230,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,1758,756,202,466,1059,1532,1158,1305,1199,225,373,54,1533,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,2134,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,-0.46522306940850683,0.3013170110599651,1.2290815354843998,0.6269572845849924,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.2857688748733796,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.8202718560579666,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Clec7a dectin 1 signaling
| 16
| 43
| 2.570556
| 0.010154
|
P28070,O43865,O00231,Q99436,O43242,P49720,P20618,Q15008,P28072,Q9UL46,P61289,P49721,P49427,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,505,251,164,533,230,202,499,373,147,436,56,407,408,470,54
|
251,1266,2221,1226,533,505,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,407,230,56,557,994,408,1540,1350,436,845,1279,884,470,821,695,2269,2215,499,1287,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,0.58240161346863,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,0.7142445586094798,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,-0.2857688748733796,-0.1430695347463049,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,-0.08762466761145592,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Sterol binding
| 6
| 14
| 2.5702
| 0.010164
|
P21796,P45880,P30536,O95772,Q14108,Q9BZF1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
4,7,73,51,84,264
|
977,1961,51,1965,4,1797,2118,73,255,7,84,830,2300,264
|
0.1254502957539166,-0.65444091817572,2.5544363806012425,-0.65444091817572,3.838410894509741,-0.4960569056469889,-0.8202718560579666,2.238325990048142,1.0603817720347808,3.6667004853346468,2.119881427808456,0.25201882658425456,-1.1768795353111265,1.0603817720347808
| 2,468
|
Sphingolipid metabolism
| 7
| 9
| 2.561895
| 0.01041
|
Q06136,P04062,O95470,P07602,O15269,Q16739,Q9NZ01
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
98,236,269,31,153,92,161
|
153,269,236,31,609,98,361,92,161
|
1.4909169970454357,1.0216002256059087,1.117653769245169,2.908601987092757,0.44490440798943937,1.9251128862095315,0.7991941651751763,2.024171009993822,1.457299817470005
| 2,468
|
Endoplasmic reticulum golgi intermediate compartment membrane
| 7
| 23
| 2.560193
| 0.010461
|
P24390,Q8N511,Q9Y3Q3,Q10472,Q9Y282,P49257,Q15904
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
5,6,368,138,21,119,284
|
683,1681,2086,5,2030,119,692,1735,998,471,138,1741,923,698,284,6,624,747,1597,21,946,367,368
|
0.3739010819588171,-0.4043641190777143,-0.7864806683003362,3.8314985860427604,-0.7198459356446938,1.7468979457042964,0.3739010819588171,-0.4346601796282852,0.1254502957539166,0.6269572845849924,1.6056618506283145,-0.4346601796282852,0.17666003360338126,0.3739010819588171,0.9823261264765617,3.681490447648572,0.44490440798943937,0.3256911134093675,-0.3150370549937861,3.129814463490708,0.17666003360338126,0.7991941651751763,0.7991941651751763
| 2,468
|
Cellular response to hypoxia
| 14
| 40
| 2.558378
| 0.010516
|
P28070,Q99436,O00231,O43242,P49720,Q9Y241,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,251,533,230,532,202,499,147,436,56,408,373,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,1249,2215,499,1034,1909,164,1177,147,1265,532
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,-0.06023936284890438,-0.958720173237647,0.6047569844332618,0.09954637705818221,-0.590226648688484,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438,0.5598892765754294
| 2,468
|
S phase
| 27
| 78
| 2.55473
| 0.010627
|
Q16763,O00231,Q07864,Q9UL46,P33991,P60900,Q99436,O43242,Q9Y2S7,P51665,P61289,P49721,P49736,P28074,Q9BRT9,P49841,P20618,Q14566,P63208,P33993,P24941,P28070,P11802,P49720,Q15008,Q9Y619,P28072
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
260,251,526,147,405,408,164,533,569,557,436,56,435,54,457,327,202,452,470,468,224,225,223,230,499,125,373
|
251,1266,2221,1226,533,1228,2366,1640,1894,223,982,756,202,224,633,1059,1532,1158,1305,1022,1199,225,373,54,1344,1492,405,1060,468,1763,576,1734,1872,988,989,1898,1240,1093,917,230,56,435,327,557,994,408,436,845,1279,884,470,821,526,963,695,696,2269,452,1583,2215,499,260,798,1173,164,1177,457,703,1721,1782,710,1013,774,147,1265,1225,569,125
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.06023936284890438,-1.4489724671135231,-0.3743308591385381,-0.590226648688484,1.1552498319919475,0.1254502957539166,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.42140856532916043,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,0.09954637705818221,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.1430695347463049,-0.2567482190180186,0.7142445586094798,0.07343946733113242,0.6269572845849924,-0.46522306940850683,0.49139101679695213,-0.4346601796282852,-0.5585543448403263,0.1254502957539166,0.1254502957539166,-0.590226648688484,-0.06023936284890438,0.047126781746465576,0.17666003360338126,1.1365094929601929,2.4964247239663777,0.6709000913867084,0.8819129546814536,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.6269572845849924,0.25201882658425456,0.5598892765754294,0.15115395482942545,0.3739010819588171,0.3739010819588171,-1.1026963504909864,0.6490043765907978,-0.3150370549937861,-0.958720173237647,0.6047569844332618,1.0603817720347808,0.27676037958362715,-0.006127331605984542,1.4232989777185565,-0.006127331605984542,0.6490043765907978,0.3739010819588171,-0.4043641190777143,-0.46522306940850683,0.3739010819588171,0.1254502957539166,0.3013170110599651,1.5406396934742081,-0.06023936284890438,-0.033074608598505244,0.5143859578494419,1.6692773995529553
| 2,468
|
Downstream signaling events of b cell receptor bcr
| 15
| 39
| 2.548878
| 0.010807
|
P28070,Q99436,O43242,O00231,P49720,P20618,Q15008,P62942,P28072,Q9UL46,P61289,P49721,P60900,P63208,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
225,164,533,251,230,202,499,238,373,147,436,56,408,470,54
|
251,1266,2221,1226,533,1640,756,202,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,238,470,821,695,2269,2215,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,0.3013170110599651,1.2290815354843998,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,1.117653769245169,0.6269572845849924,0.25201882658425456,0.3739010819588171,-1.1026963504909864,-0.958720173237647,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
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