term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Regulation of transmembrane receptor protein serine threonine kinase signaling pathway
| 7
| 19
| 2.477165
| 0.013243
|
Q92896,P62942,Q8N0X7,P09874,Q8N1F7,Q14980,P04637
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
393,154,167,14,541,537,529
|
827,529,1077,14,977,154,767,1046,1298,537,167,541,393,1667,1439,857,858,568,1630
|
0.26262791247117023,0.5566115286243463,0.09425478550483424,3.9740289947398435,0.15104226553426064,1.4925203872541544,0.31745440163525057,0.12273293000494902,-0.021383766664227755,0.5566115286243463,1.407013911282315,0.5566115286243463,0.784211761763469,-0.26136298554392196,-0.1099799759281711,0.26262791247117023,0.26262791247117023,0.5306286544959777,-0.23070398700916023
| 2,702
|
Sumoylation of ubiquitinylation proteins
| 14
| 27
| 2.465779
| 0.013672
|
P49792,Q8NFH4,P35658,O75694,O75928,P12270,Q8N1F7,Q9BTX1,Q9BVL2,P55735,Q99567,Q8WUM0,Q12769,Q7Z3B4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
288,226,3,599,670,293,541,542,504,738,639,777,495,685
|
599,670,293,3,1235,1456,288,1546,738,905,1606,495,914,685,541,226,1659,1385,777,779,1306,639,542,504,926,2078,1481
|
0.4782294385308354,0.39852436325326,1.0012473661035215,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,-0.20023841286057453,0.3446320422674998,0.2071618461975449,-0.23070398700916023,0.6081511143176388,0.2071618461975449,0.39852436325326,0.5566115286243463,1.1860066448125965,-0.26136298554392196,-0.08026602431198727,0.31745440163525057,0.31745440163525057,-0.021383766664227755,0.45181010850325676,0.5566115286243463,0.6081511143176388,0.2071618461975449,-0.5463883460250468,-0.1398785959133766
| 2,702
|
B cell activation
| 9
| 32
| 2.460434
| 0.013877
|
P17812,Q5JVF3,Q14790,Q9UQ84,P00813,O96028,P78318,P14174,Q9NQT5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,163,329,71,42,75,118,56,59
|
1269,1490,75,42,2356,529,2372,1773,2006,56,64,2360,1137,630,441,118,907,1368,1193,329,1152,2655,163,330,1746,916,1809,998,1811,59,71,2040
|
-0.021383766664227755,-0.1699640181909275,2.233303018813176,2.6938037281589335,-0.8491105936663824,0.5566115286243463,-0.8839284596697314,-0.35452356200396523,-0.5138808228281478,2.4094934860042883,2.3573660616958487,-0.8491105936663824,0.06560596082580177,0.45181010850325676,0.7095652084505555,1.7598374077792183,0.2071618461975449,-0.08026602431198727,0.036784554335826614,0.9300199004069388,0.06560596082580177,-1.8445118508373655,1.4285407486745718,0.9300199004069388,-0.3232704296671488,0.2071618461975449,-0.35452356200396523,0.15104226553426064,-0.35452356200396523,2.4094934860042883,2.2868970423085044,-0.5138808228281478
| 2,702
|
Peroxisomal protein import
| 7
| 18
| 2.447419
| 0.014388
|
O75381,O15254,Q9BY49,O75874,O00116,Q15067,Q13011
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
99,103,85,54,334,155,92
|
334,1725,103,99,1635,54,797,1929,1640,2374,365,2061,1792,92,155,1387,85,2229
|
0.9060329793006716,-0.3232704296671488,1.9168361544314048,1.9552468158064782,-0.26136298554392196,2.4267339760166293,0.29012025009768083,-0.449509590099947,-0.26136298554392196,-0.8839284596697314,0.8333224319696179,-0.5463883460250468,-0.35452356200396523,2.031097928717653,1.4925203872541544,-0.08026602431198727,2.1425231720053195,-0.6786274687643568
| 2,702
|
Negative regulation of mrna processing
| 10
| 22
| 2.44611
| 0.014441
|
Q13247,Q13242,Q16629,P50750,P98175,Q5VTR2,O75494,P61978,P38159,P22626
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
520,263,428,389,310,211,182,153,91,159
|
1401,2230,549,182,652,159,1183,1453,91,389,153,310,1242,909,1988,263,520,1945,428,211,841,1558
|
-0.1099799759281711,-0.7122535027473694,0.5306286544959777,1.319881581600934,0.42524226721919817,1.4499668634992937,0.036784554335826614,-0.1398785959133766,2.031097928717653,0.784211761763469,1.4925203872541544,0.9776259405477873,0.007788633325283703,0.2071618461975449,-0.48158877982782056,1.0945486200442405,0.5824518687603596,-0.449509590099947,0.7345798472794599,1.231065281813778,0.26262791247117023,-0.20023841286057453
| 2,702
|
Signal sequence binding
| 9
| 26
| 2.445556
| 0.014463
|
P35658,Q9UHB9,P52292,Q9BVL2,Q15388,P24390,P50542,P40855,O60684
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
3,567,296,504,473,21,365,337,184
|
938,1674,1582,184,1317,21,3,1691,337,1456,365,296,735,1546,2215,949,740,1149,982,473,1304,616,2029,504,1068,567
|
0.1791846335137533,-0.2922176920491657,-0.23070398700916023,1.2978377151319078,-0.05073464252917762,3.5442257241440536,4.779930332154013,-0.2922176920491657,0.9060329793006716,-0.1398785959133766,0.8333224319696179,1.0012473661035215,0.3446320422674998,-0.20023841286057453,-0.6786274687643568,0.1791846335137533,0.3446320422674998,0.06560596082580177,0.15104226553426064,0.6591319741805618,-0.021383766664227755,0.4782294385308354,-0.5138808228281478,0.6081511143176388,0.12273293000494902,0.5306286544959777
| 2,702
|
Receptor
| 8
| 25
| 2.437306
| 0.014797
|
Q08AM6,O75381,Q567V2,Q9NR77,Q14108,Q13432,Q9UQB8,A6NIH7
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
290,99,38,344,147,83,93,31
|
31,1632,2232,99,2298,2299,1773,674,576,533,290,83,1509,147,38,2146,372,778,1436,1573,344,1921,1576,93,1672
|
3.125248693369596,-0.26136298554392196,-0.7122535027473694,1.9552468158064782,-0.780205401999509,-0.780205401999509,-0.35452356200396523,0.39852436325326,0.504501785431343,0.5566115286243463,1.0247492400647817,2.1425231720053195,-0.1699640181909275,1.5346812984581808,2.7260759733711035,-0.6120605797493264,0.8333224319696179,0.31745440163525057,-0.1099799759281711,-0.20023841286057453,0.9060329793006716,-0.4176406731946431,-0.20023841286057453,2.031097928717653,-0.26136298554392196
| 2,702
|
K Homology domain, type 1 [IPR004088]
| 10
| 21
| 2.431159
| 0.015051
|
Q9Y2W6,P51116,Q92945,Q96AE4,Q07666,P61978,Q9Y6M1,Q9NQT5,Q13868,P51114
|
Sequence
|
InterPro Domain
|
interpro_domain
|
201,196,265,272,270,153,385,59,279,289
|
792,289,196,1936,153,1141,270,279,1904,2573,1853,2365,1661,265,272,445,1519,59,1393,201,385
|
0.29012025009768083,1.0247492400647817,1.2756876781734239,-0.449509590099947,1.4925203872541544,0.06560596082580177,1.0713987752533087,1.0481326767167887,-0.4176406731946431,-1.2840336152236627,-0.385979494061243,-0.8491105936663824,-0.26136298554392196,1.0945486200442405,1.0713987752533087,0.7095652084505555,-0.1699640181909275,2.4094934860042883,-0.08026602431198727,1.2756876781734239,0.8088316185366753
| 2,702
|
Alternative mrna splicing via spliceosome
| 20
| 38
| 2.425989
| 0.015267
|
Q9Y2W1,Q13247,Q13242,Q07666,Q8IY67,P51114,Q96MU7,P17844,P98175,P51116,P52272,P52756,Q9UHX1,Q9BWF3,Q07955,P38159,Q8NDT2,P09651,P62995,P23246
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
396,520,263,270,540,289,560,417,310,196,454,455,345,212,339,91,482,604,235,242
|
2230,1073,604,864,417,242,1453,2097,91,1645,289,196,1936,454,455,235,310,1088,270,339,910,1988,263,520,1945,1855,540,482,638,1753,881,560,848,212,345,396,1630,1121
|
-0.7122535027473694,0.09425478550483424,0.4782294385308354,0.2349756872773074,0.7345798472794599,1.1405038133141903,-0.1398785959133766,-0.5791140239235776,2.031097928717653,-0.26136298554392196,1.0247492400647817,1.2756876781734239,-0.449509590099947,0.6844163633500198,0.6844163633500198,1.1633112587408174,0.9776259405477873,0.09425478550483424,1.0713987752533087,0.9060329793006716,0.2071618461975449,-0.48158877982782056,1.0945486200442405,0.5824518687603596,-0.449509590099947,-0.385979494061243,0.5566115286243463,0.6337106835947478,0.45181010850325676,-0.3232704296671488,0.2349756872773074,0.5306286544959777,0.26262791247117023,1.231065281813778,0.9060329793006716,0.784211761763469,-0.23070398700916023,0.09425478550483424
| 2,702
|
Structural constituent of cytoskeleton
| 15
| 34
| 2.409469
| 0.015976
|
Q16204,P09493,Q13885,Q9Y2J2,P15924,Q9BVA1,Q15149,P07197,O95619,Q16352,P08670,P68371,P07437,O15020,P07196
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
197,130,522,510,326,206,371,230,17,148,49,404,336,347,185
|
1486,347,1767,2162,17,832,185,230,336,49,130,1683,326,1886,1495,1788,2512,2342,404,535,874,711,522,2280,371,197,148,1994,1168,206,1437,510,967,1485
|
-0.1699640181909275,0.8819218929788717,-0.35452356200396523,-0.6452307866220199,3.7519363221998616,0.26262791247117023,1.2978377151319078,1.1633112587408174,0.9060329793006716,2.511943158877311,1.6588740220805571,-0.2922176920491657,0.9300199004069388,-0.4176406731946431,-0.1699640181909275,-0.35452356200396523,-1.1347798177249695,-0.8145372938985567,0.7594615984524137,0.5566115286243463,0.2349756872773074,0.3716548214149085,0.5824518687603596,-0.7461118187735932,0.8333224319696179,1.2756876781734239,1.5346812984581808,-0.48158877982782056,0.06560596082580177,1.2534305210935053,-0.1099799759281711,0.6081511143176388,0.1791846335137533,-0.1398785959133766
| 2,702
|
Regulation of glucokinase by glucokinase regulatory protein
| 13
| 26
| 2.388523
| 0.016916
|
P49792,Q8NFH4,P35658,O75694,Q9BVL2,P12270,Q8N1F7,Q9BTX1,P55735,Q99567,Q8WUM0,Q12769,Q7Z3B4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
288,226,3,599,504,293,541,542,738,639,777,495,685
|
599,293,3,1235,1456,288,1546,738,905,1606,495,914,685,541,226,1659,1385,777,779,1306,639,542,504,926,2078,1481
|
0.4782294385308354,1.0012473661035215,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,-0.20023841286057453,0.3446320422674998,0.2071618461975449,-0.23070398700916023,0.6081511143176388,0.2071618461975449,0.39852436325326,0.5566115286243463,1.1860066448125965,-0.26136298554392196,-0.08026602431198727,0.31745440163525057,0.31745440163525057,-0.021383766664227755,0.45181010850325676,0.5566115286243463,0.6081511143176388,0.2071618461975449,-0.5463883460250468,-0.1398785959133766
| 2,702
|
Sumoylation of sumoylation proteins
| 13
| 26
| 2.388523
| 0.016916
|
P49792,Q8NFH4,P35658,O75694,Q9BVL2,P12270,Q8N1F7,Q9BTX1,P55735,Q99567,Q8WUM0,Q12769,Q7Z3B4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
288,226,3,599,504,293,541,542,738,639,777,495,685
|
599,293,3,1235,1456,288,1546,738,905,1606,495,914,685,541,226,1659,1385,777,779,1306,639,542,504,926,2078,1481
|
0.4782294385308354,1.0012473661035215,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,-0.20023841286057453,0.3446320422674998,0.2071618461975449,-0.23070398700916023,0.6081511143176388,0.2071618461975449,0.39852436325326,0.5566115286243463,1.1860066448125965,-0.26136298554392196,-0.08026602431198727,0.31745440163525057,0.31745440163525057,-0.021383766664227755,0.45181010850325676,0.5566115286243463,0.6081511143176388,0.2071618461975449,-0.5463883460250468,-0.1398785959133766
| 2,702
|
Transport of the slbp dependant mature mrna
| 14
| 29
| 2.385973
| 0.017034
|
P49792,Q8NFH4,P35658,O75694,Q9BVL2,P12270,Q8N1F7,Q9BTX1,P55735,Q99567,Q86V81,Q8WUM0,Q12769,Q7Z3B4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
288,226,3,599,504,293,541,542,738,639,408,777,495,685
|
599,293,3,1235,1456,288,1546,738,905,1606,1508,495,914,685,408,541,226,1659,1385,777,779,1306,639,542,504,926,2078,1759,1481
|
0.4782294385308354,1.0012473661035215,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,-0.20023841286057453,0.3446320422674998,0.2071618461975449,-0.23070398700916023,-0.1699640181909275,0.6081511143176388,0.2071618461975449,0.39852436325326,0.7594615984524137,0.5566115286243463,1.1860066448125965,-0.26136298554392196,-0.08026602431198727,0.31745440163525057,0.31745440163525057,-0.021383766664227755,0.45181010850325676,0.5566115286243463,0.6081511143176388,0.2071618461975449,-0.5463883460250468,-0.3232704296671488,-0.1398785959133766
| 2,702
|
transporter
| 13
| 56
| 2.381821
| 0.017227
|
P35658,P41440,P53985,Q567V2,Q6N075,Q9H2D1,O43772,P52292,Q9HD45,Q15070,Q99595,O60684,Q8NFH4
|
Functions
|
Panther Protein class
|
panther_protein_class
|
3,67,100,38,134,73,9,296,213,116,22,184,226
|
938,1674,1582,2552,1632,387,1316,1124,9,184,599,625,3,1235,67,1693,1456,296,735,1546,100,659,1602,738,905,949,495,1149,116,38,134,685,541,226,1385,1304,1305,616,1306,997,639,22,2033,748,2347,1208,73,2632,1573,213,344,755,1957,693,1529,936
|
0.1791846335137533,-0.2922176920491657,-0.23070398700916023,-1.246298549886792,-0.26136298554392196,0.784211761763469,-0.05073464252917762,0.06560596082580177,4.1389954392444945,1.2978377151319078,0.4782294385308354,0.45181010850325676,4.779930332154013,0.007788633325283703,2.339853291567594,-0.2922176920491657,-0.1398785959133766,1.0012473661035215,0.3446320422674998,-0.20023841286057453,1.9552468158064782,0.42524226721919817,-0.23070398700916023,0.3446320422674998,0.2071618461975449,0.1791846335137533,0.6081511143176388,0.06560596082580177,1.7996013420160522,2.7260759733711035,1.6178517102360863,0.39852436325326,0.5566115286243463,1.1860066448125965,-0.08026602431198727,-0.021383766664227755,-0.021383766664227755,0.4782294385308354,-0.021383766664227755,0.15104226553426064,0.45181010850325676,3.4500635955114625,-0.5138808228281478,0.3446320422674998,-0.8145372938985567,0.036784554335826614,2.2691039308231553,-1.5564687430126587,-0.20023841286057453,1.231065281813778,0.9060329793006716,0.3446320422674998,-0.449509590099947,0.39852436325326,-0.1699640181909275,0.2071618461975449
| 2,702
|
Wide anterior fontanel
| 8
| 20
| 2.379895
| 0.017318
|
O75381,Q16134,Q08J23,P50542,O75718,Q32P28,Q9Y487,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,28,424,365,307,27,156,337
|
99,414,307,2302,1081,1030,2052,2010,2543,337,974,365,424,2407,1196,28,27,988,1474,156
|
1.9552468158064782,0.7345798472794599,0.9776259405477873,-0.780205401999509,0.09425478550483424,0.12273293000494902,-0.5463883460250468,-0.5138808228281478,-1.208847161551696,0.9060329793006716,0.15104226553426064,0.8333224319696179,0.7345798472794599,-0.9189941109407576,0.036784554335826614,3.1979755531726313,3.2836590722958277,0.15104226553426064,-0.1398785959133766,1.4925203872541544
| 2,702
|
Abnormality of muscle size
| 39
| 167
| 2.37116
| 0.017732
|
P55263,O14979,Q9NWM8,Q8N2K0,P50995,Q15813,P31749,Q9BQT8,P61978,O95831,Q9Y487,P22626,Q13126,P21281,O00429,Q8N0X7,Q16637,Q92734,Q15165,Q7Z406,P50402,Q9ULV3,P02545,Q6DKK2,Q9NQT5,P07196,O75477,Q9BVA1,Q9NR77,Q8TD16,P35637,Q03252,O60568,Q92804,Q15149,P06753,P50542,O43505,Q9BUK6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,128,135,264,390,407,145,23,153,26,156,159,32,287,285,167,170,301,43,173,295,313,178,53,59,185,323,206,344,343,81,338,335,90,371,229,365,362,126
|
1264,896,1219,285,2610,2161,2083,939,451,128,1531,1488,968,362,2329,1405,571,335,1490,323,491,970,2131,26,178,1585,2627,229,185,1774,2587,1321,603,604,1881,1733,2654,2554,1588,2556,2169,287,2052,1322,1885,159,1181,605,2305,2097,145,1135,903,81,2682,2580,1543,578,948,2240,805,1184,1237,295,365,977,390,2014,1601,2376,607,978,2595,1501,2271,1938,0,2492,153,1422,2381,338,2016,582,2219,1243,2561,519,2620,32,811,769,1699,609,425,661,1426,876,406,840,371,43,2448,407,170,2547,1155,53,877,989,2498,1098,173,1517,1859,167,264,955,2365,343,686,301,90,1205,2437,1710,1865,639,1344,999,925,2197,447,23,2199,1618,126,206,665,2288,725,1574,2453,2254,59,344,1715,2117,1479,135,1997,1872,1216,1480,1261,313,1439,568,2327,1763,156,2328,597,2041,1121,1723,791
|
-0.021383766664227755,0.2071618461975449,0.007788633325283703,1.0247492400647817,-1.477107037869868,-0.6452307866220199,-0.5791140239235776,0.1791846335137533,0.6844163633500198,1.6588740220805571,-0.20023841286057453,-0.1699640181909275,0.15104226553426064,0.8333224319696179,-0.8145372938985567,-0.1099799759281711,0.504501785431343,0.9060329793006716,-0.1699640181909275,0.9300199004069388,0.6081511143176388,0.15104226553426064,-0.6120605797493264,3.3258692872450646,1.341820214976906,-0.23070398700916023,-1.5564687430126587,1.1633112587408174,1.2978377151319078,-0.35452356200396523,-1.3603708589860188,-0.05073464252917762,0.4782294385308354,0.4782294385308354,-0.4176406731946431,-0.3232704296671488,-1.8445118508373655,-1.246298549886792,-0.23070398700916023,-1.246298549886792,-0.6452307866220199,1.0247492400647817,-0.5463883460250468,-0.05073464252917762,-0.4176406731946431,1.4499668634992937,0.036784554335826614,0.4782294385308354,-0.780205401999509,-0.5791140239235776,1.5346812984581808,0.06560596082580177,0.2071618461975449,2.160827351832918,-2.7198385003315337,-1.3220563573737758,-0.20023841286057453,0.504501785431343,0.1791846335137533,-0.7122535027473694,0.29012025009768083,0.036784554335826614,0.007788633325283703,1.0012473661035215,0.8333224319696179,0.15104226553426064,0.784211761763469,-0.5138808228281478,-0.23070398700916023,-0.8839284596697314,0.4782294385308354,0.15104226553426064,-1.3989812878170513,-0.1699640181909275,-0.7461118187735932,-0.449509590099947,5.624527738523166,-1.0981562573910337,1.4925203872541544,-0.1099799759281711,-0.8839284596697314,0.9060329793006716,-0.5138808228281478,0.504501785431343,-0.6786274687643568,0.007788633325283703,-1.246298549886792,0.5824518687603596,-1.516631141683355,3.08101788485959,0.29012025009768083,0.31745440163525057,-0.2922176920491657,0.4782294385308354,0.7345798472794599,0.42524226721919817,-0.1099799759281711,0.2349756872773074,0.7594615984524137,0.26262791247117023,0.8333224319696179,2.677578161237687,-0.9898819580382101,0.7594615984524137,1.3853854720918395,-1.208847161551696,0.06560596082580177,2.4439076160408386,0.2349756872773074,0.15104226553426064,-1.0981562573910337,0.09425478550483424,1.363654540627114,-0.1699640181909275,-0.385979494061243,1.407013911282315,1.0945486200442405,0.1791846335137533,-0.8491105936663824,0.9060329793006716,0.39852436325326,1.0012473661035215,2.049862232695574,0.036784554335826614,-0.9543108287183288,-0.2922176920491657,-0.385979494061243,0.45181010850325676,-0.05073464252917762,0.15104226553426064,0.2071618461975449,-0.6452307866220199,0.7095652084505555,3.4500635955114625,-0.6452307866220199,-0.23070398700916023,1.6995293541371095,1.2534305210935053,0.42524226721919817,-0.7461118187735932,0.3716548214149085,-0.20023841286057453,-0.9898819580382101,-0.7122535027473694,2.4094934860042883,0.9060329793006716,-0.2922176920491657,-0.5791140239235776,-0.1398785959133766,1.6178517102360863,-0.48158877982782056,-0.385979494061243,0.036784554335826614,-0.1398785959133766,0.007788633325283703,0.9776259405477873,-0.1099799759281711,0.5306286544959777,-0.780205401999509,-0.3232704296671488,1.4925203872541544,-0.780205401999509,0.504501785431343,-0.5138808228281478,0.09425478550483424,-0.2922176920491657,0.31745440163525057
| 2,702
|
Cellular response to inorganic substance
| 12
| 29
| 2.347955
| 0.018877
|
P25705,Q9NQ88,Q15334,Q99829,Q14103,P09874,P28482,P35611,P31749,P27361,O95831,Q92542
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
252,524,458,240,237,14,655,577,145,653,26,588
|
1125,26,672,1130,14,252,653,2054,655,2443,1033,145,577,1497,948,1037,977,874,237,1334,458,987,988,588,783,1000,240,524,2206
|
0.06560596082580177,3.3258692872450646,0.39852436325326,0.06560596082580177,3.9740289947398435,1.1175832808973218,0.42524226721919817,-0.5463883460250468,0.42524226721919817,-0.9898819580382101,0.12273293000494902,1.5346812984581808,0.504501785431343,-0.1699640181909275,0.1791846335137533,0.12273293000494902,0.15104226553426064,0.2349756872773074,1.1633112587408174,-0.05073464252917762,0.6844163633500198,0.15104226553426064,0.15104226553426064,0.504501785431343,0.31745440163525057,0.15104226553426064,1.1633112587408174,0.5824518687603596,-0.6452307866220199
| 2,702
|
Thin ribs
| 6
| 11
| 2.332878
| 0.019655
|
O75844,O14802,Q15813,P02545,O95831,Q32P28
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
314,451,407,178,26,27
|
451,490,314,26,178,1364,977,1791,407,27,936
|
0.6844163633500198,0.6081511143176388,0.9538838337472978,3.3258692872450646,1.341820214976906,-0.08026602431198727,0.15104226553426064,-0.35452356200396523,0.7594615984524137,3.2836590722958277,0.2071618461975449
| 2,702
|
Dolichocephaly
| 14
| 25
| 2.32894
| 0.019862
|
Q08AM6,P21281,Q01082,Q4J6C6,O75381,O95721,O96028,Q9BXW9,P31749,Q99622,P50542,P40855,P61978,Q03164
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,287,535,198,99,602,75,562,145,640,365,337,153,62
|
99,1878,2088,602,75,2133,287,654,145,337,975,948,1416,365,2061,153,535,62,290,1899,2407,198,640,562,1716
|
1.9552468158064782,-0.4176406731946431,-0.5791140239235776,0.4782294385308354,2.233303018813176,-0.6120605797493264,1.0247492400647817,0.42524226721919817,1.5346812984581808,0.9060329793006716,0.15104226553426064,0.1791846335137533,-0.1099799759281711,0.8333224319696179,-0.5463883460250468,1.4925203872541544,0.5566115286243463,2.374810019413564,1.0247492400647817,-0.4176406731946431,-0.9189941109407576,1.2756876781734239,0.45181010850325676,0.5306286544959777,-0.2922176920491657
| 2,702
|
Peroxisome
| 11
| 29
| 2.328789
| 0.01987
|
O75381,O15254,Q9BQG2,Q9NR77,Q9BY49,O75874,P40855,P48735,O00116,Q15067,Q13011
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
99,103,45,344,85,54,337,24,334,155,92
|
334,1725,103,2085,1963,99,1635,54,1228,2677,797,1640,1287,2359,2400,2374,337,24,365,2061,1792,92,155,2021,2537,45,85,344,2229
|
0.9060329793006716,-0.3232704296671488,1.9168361544314048,-0.5791140239235776,-0.48158877982782056,1.9552468158064782,-0.26136298554392196,2.4267339760166293,0.007788633325283703,-2.2865857970685295,0.29012025009768083,-0.26136298554392196,-0.021383766664227755,-0.8491105936663824,-0.9189941109407576,-0.8839284596697314,0.9060329793006716,3.3953101294729233,0.8333224319696179,-0.5463883460250468,-0.35452356200396523,2.031097928717653,1.4925203872541544,-0.5138808228281478,-1.1716755310485276,2.6449460890363556,2.1425231720053195,0.9060329793006716,-0.6786274687643568
| 2,702
|
Transition metal ion binding
| 39
| 165
| 2.299253
| 0.021491
|
Q9Y5J9,P55786,P09874,Q8N4Q0,Q32P28,Q16629,P13674,P00403,Q96T88,P00813,Q16850,Q9BQG2,O60888,Q9ULV3,O15460,Q9UIQ6,Q03164,P19474,P42892,P22830,Q8NB78,Q9BWF3,P49356,O60568,Q9NZ08,Q6NZY4,Q9BV57,Q9NQH7,P51003,O95487,Q99829,Q5JRX3,Q9Y5J7,O43823,O14735,P34896,P62875,Q9NUD5,Q9BU89
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
398,13,14,15,27,428,34,165,435,42,298,45,48,313,55,191,62,65,194,203,342,212,216,335,221,349,351,357,224,223,240,239,377,106,361,243,366,122,125
|
2662,1123,361,828,55,1831,106,335,48,1726,528,1727,701,670,1076,1448,2209,2087,1537,1771,1126,1680,223,2524,1449,2088,165,42,2677,2442,529,1731,1833,14,2301,1078,2133,2660,34,1929,2556,1179,65,203,758,1777,1642,1360,2054,2457,1593,1888,802,243,1289,2675,2374,866,2682,2058,194,578,761,834,216,805,2241,1237,224,2062,1040,1418,13,979,366,741,1791,62,1608,808,1896,2312,1144,1610,911,1462,1297,1794,426,1797,1373,1149,2635,1337,1196,2448,1853,2482,428,1557,298,27,2408,2108,239,1338,2109,1515,1430,349,2283,1747,1157,842,1101,1382,1340,1911,15,2669,342,2534,2678,2285,921,1342,589,435,782,2623,1109,1000,2317,240,45,125,351,212,2288,2250,1309,357,1211,122,1213,964,1114,221,965,2569,1216,1261,191,2647,313,2645,858,1313,486,2294,597,487,377,398,791
|
-1.9731578815729123,0.06560596082580177,0.8333224319696179,0.26262791247117023,2.4094934860042883,-0.385979494061243,1.8975073051504956,0.9060329793006716,2.511943158877311,-0.3232704296671488,0.5566115286243463,-0.3232704296671488,0.3716548214149085,0.39852436325326,0.09425478550483424,-0.1398785959133766,-0.6786274687643568,-0.5791140239235776,-0.20023841286057453,-0.35452356200396523,0.06560596082580177,-0.2922176920491657,1.1860066448125965,-1.1716755310485276,-0.1398785959133766,-0.5791140239235776,1.407013911282315,2.6938037281589335,-2.2865857970685295,-0.9898819580382101,0.5566115286243463,-0.3232704296671488,-0.385979494061243,3.9740289947398435,-0.780205401999509,0.09425478550483424,-0.6120605797493264,-1.929913063783283,2.8528380007812295,-0.449509590099947,-1.246298549886792,0.036784554335826614,2.3573660616958487,1.2534305210935053,0.31745440163525057,-0.35452356200396523,-0.26136298554392196,-0.08026602431198727,-0.5463883460250468,-1.0257109093739025,-0.23070398700916023,-0.4176406731946431,0.29012025009768083,1.1405038133141903,-0.021383766664227755,-2.195059359857069,-0.8839284596697314,0.2349756872773074,-2.7198385003315337,-0.5463883460250468,1.2756876781734239,0.504501785431343,0.31745440163525057,0.26262791247117023,1.208590985594112,0.29012025009768083,-0.7122535027473694,0.007788633325283703,1.1860066448125965,-0.5463883460250468,0.12273293000494902,-0.1099799759281711,3.9860302897388693,0.15104226553426064,0.8333224319696179,0.3446320422674998,-0.35452356200396523,2.374810019413564,-0.23070398700916023,0.29012025009768083,-0.4176406731946431,-0.780205401999509,0.06560596082580177,-0.23070398700916023,0.2071618461975449,-0.1398785959133766,-0.021383766664227755,-0.35452356200396523,0.7345798472794599,-0.35452356200396523,-0.08026602431198727,0.06560596082580177,-1.6371030594285456,-0.05073464252917762,0.036784554335826614,-0.9898819580382101,-0.385979494061243,-1.0618011603301436,0.7345798472794599,-0.20023841286057453,1.0012473661035215,3.2836590722958277,-0.9189941109407576,-0.5791140239235776,1.1633112587408174,-0.05073464252917762,-0.5791140239235776,-0.1699640181909275,-0.1099799759281711,0.8819218929788717,-0.7461118187735932,-0.3232704296671488,0.06560596082580177,0.26262791247117023,0.09425478550483424,-0.08026602431198727,-0.05073464252917762,-0.4176406731946431,3.839701860183123,-2.105138935214665,0.9060329793006716,-1.1716755310485276,-2.2865857970685295,-0.7461118187735932,0.2071618461975449,-0.05073464252917762,0.504501785431343,0.7345798472794599,0.31745440163525057,-1.516631141683355,0.09425478550483424,0.15104226553426064,-0.780205401999509,1.1633112587408174,2.6449460890363556,1.6995293541371095,0.8819218929788717,1.231065281813778,-0.7461118187735932,-0.7122535027473694,-0.021383766664227755,0.8576854474690445,0.036784554335826614,1.7197212915351867,0.036784554335826614,0.1791846335137533,0.09425478550483424,1.208590985594112,0.1791846335137533,-1.246298549886792,0.036784554335826614,0.007788633325283703,1.2978377151319078,-1.719048251733198,0.9776259405477873,-1.6779093391999742,0.26262791247117023,-0.021383766664227755,0.6337106835947478,-0.7461118187735932,0.504501785431343,0.6337106835947478,0.8333224319696179,0.784211761763469,0.31745440163525057
| 2,702
|
Intermediate filament
| 10
| 18
| 2.299188
| 0.021494
|
P15924,P48681,Q15149,P07197,P08670,Q16352,P02545,Q03252,P14923,P07196
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
326,233,371,230,49,148,178,338,402,185
|
1961,178,185,230,49,402,326,418,233,1599,1847,1502,2672,338,371,148,1112,596
|
-0.48158877982782056,1.341820214976906,1.2978377151319078,1.1633112587408174,2.511943158877311,0.7594615984524137,0.9300199004069388,0.7345798472794599,1.1633112587408174,-0.23070398700916023,-0.385979494061243,-0.1699640181909275,-2.149901662757291,0.9060329793006716,0.8333224319696179,1.5346812984581808,0.09425478550483424,0.504501785431343
| 2,702
|
Positive regulation of gene expression
| 38
| 196
| 2.282944
| 0.022434
|
Q99729,Q96AE4,Q07666,P31749,P51114,Q13217,O14737,Q567V2,Q9NUQ9,P08670,Q96HY6,O94788,P02545,P98175,P14174,Q9NQT5,P98179,O60684,P07910,O75844,P35579,P41440,Q9H2J4,P51116,Q14790,P16989,O96028,Q6P1A2,P35637,Q9Y2R0,Q92804,P38159,Q7Z4L5,Q14103,P62995,O60506,P67809,Q9NUD5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
138,272,270,145,289,291,160,38,302,49,312,52,178,310,56,59,60,184,315,314,316,67,333,196,329,72,75,76,81,215,90,91,105,237,235,111,121,122
|
668,939,160,451,570,1403,1445,1676,111,184,1726,528,2600,796,314,1227,52,1317,1537,1277,75,2423,178,2356,831,1926,2626,529,2627,1024,2476,2047,702,1407,1129,315,1832,49,2167,1130,1408,2006,1231,401,1587,56,1493,550,72,417,575,2169,2588,1452,704,1181,1495,1777,1183,833,653,2054,655,901,2095,2589,145,1234,2360,1035,316,81,706,91,1497,1084,2237,67,1325,974,630,2375,2544,1935,2100,2637,289,196,2431,1546,1041,868,1646,1847,739,764,2639,2460,2275,1942,1549,1743,235,1849,121,1327,2404,907,310,60,1088,535,1241,908,1329,1043,1242,270,910,1508,2562,1193,874,354,811,536,291,680,1147,521,1463,1046,1091,237,2104,1903,329,1555,2068,1092,1151,913,2432,2630,38,330,1746,76,990,556,2189,2499,105,1803,1562,1471,2071,2028,90,1753,1342,719,272,957,1916,312,445,1519,1063,998,1108,618,2623,1811,138,2287,1476,1064,723,724,1390,333,1919,59,1575,122,302,1214,2518,2202,1393,693,2121,2156,215,396
|
0.39852436325326,0.1791846335137533,1.4285407486745718,0.6844163633500198,0.504501785431343,-0.1099799759281711,-0.1398785959133766,-0.2922176920491657,1.8585992820751742,1.2978377151319078,-0.3232704296671488,0.5566115286243463,-1.4378918990793144,0.29012025009768083,0.9538838337472978,0.007788633325283703,2.4610148839137267,-0.05073464252917762,-0.20023841286057453,-0.021383766664227755,2.233303018813176,-0.9543108287183288,1.341820214976906,-0.8491105936663824,0.26262791247117023,-0.449509590099947,-1.5564687430126587,0.5566115286243463,-1.5564687430126587,0.12273293000494902,-1.0618011603301436,-0.5463883460250468,0.3716548214149085,-0.1099799759281711,0.06560596082580177,0.9538838337472978,-0.385979494061243,2.511943158877311,-0.6452307866220199,0.06560596082580177,-0.1099799759281711,-0.5138808228281478,0.007788633325283703,0.7594615984524137,-0.23070398700916023,2.4094934860042883,-0.1699640181909275,0.5306286544959777,2.2691039308231553,0.7345798472794599,0.504501785431343,-0.6452307866220199,-1.3603708589860188,-0.1398785959133766,0.3716548214149085,0.036784554335826614,-0.1699640181909275,-0.35452356200396523,0.036784554335826614,0.26262791247117023,0.42524226721919817,-0.5463883460250468,0.42524226721919817,0.2071618461975449,-0.5791140239235776,-1.3603708589860188,1.5346812984581808,0.007788633325283703,-0.8491105936663824,0.12273293000494902,0.9538838337472978,2.160827351832918,0.3716548214149085,2.031097928717653,-0.1699640181909275,0.09425478550483424,-0.7122535027473694,2.339853291567594,-0.05073464252917762,0.15104226553426064,0.45181010850325676,-0.8839284596697314,-1.208847161551696,-0.449509590099947,-0.5791140239235776,-1.6779093391999742,1.0247492400647817,1.2756876781734239,-0.9543108287183288,-0.20023841286057453,0.12273293000494902,0.2349756872773074,-0.26136298554392196,-0.385979494061243,0.3446320422674998,0.31745440163525057,-1.6779093391999742,-1.0257109093739025,-0.7461118187735932,-0.449509590099947,-0.20023841286057453,-0.3232704296671488,1.1633112587408174,-0.385979494061243,1.7197212915351867,-0.05073464252917762,-0.9189941109407576,0.2071618461975449,0.9776259405477873,2.3921856631301304,0.09425478550483424,0.5566115286243463,0.007788633325283703,0.2071618461975449,-0.05073464252917762,0.12273293000494902,0.007788633325283703,1.0713987752533087,0.2071618461975449,-0.1699640181909275,-1.246298549886792,0.036784554335826614,0.2349756872773074,0.8576854474690445,0.29012025009768083,0.5566115286243463,1.0247492400647817,0.39852436325326,0.06560596082580177,0.5824518687603596,-0.1398785959133766,0.12273293000494902,0.09425478550483424,1.1633112587408174,-0.5791140239235776,-0.4176406731946431,0.9300199004069388,-0.20023841286057453,-0.5463883460250468,0.09425478550483424,0.06560596082580177,0.2071618461975449,-0.9543108287183288,-1.5564687430126587,2.7260759733711035,0.9300199004069388,-0.3232704296671488,2.215294149477837,0.15104226553426064,0.5306286544959777,-0.6452307866220199,-1.0981562573910337,1.9168361544314048,-0.35452356200396523,-0.20023841286057453,-0.1398785959133766,-0.5463883460250468,-0.5138808228281478,2.049862232695574,-0.3232704296671488,-0.05073464252917762,0.3716548214149085,1.0713987752533087,0.1791846335137533,-0.4176406731946431,0.9776259405477873,0.7095652084505555,-0.1699640181909275,0.12273293000494902,0.15104226553426064,0.09425478550483424,0.4782294385308354,-1.516631141683355,-0.35452356200396523,1.5764562446123624,-0.7461118187735932,-0.1398785959133766,0.12273293000494902,0.3716548214149085,0.3716548214149085,-0.08026602431198727,0.9300199004069388,-0.4176406731946431,2.4094934860042883,-0.20023841286057453,1.7197212915351867,1.0012473661035215,0.036784554335826614,-1.1347798177249695,-0.6452307866220199,-0.08026602431198727,0.39852436325326,-0.5791140239235776,-0.6120605797493264,1.231065281813778,0.784211761763469
| 2,702
|
Translocation
| 19
| 45
| 2.278084
| 0.022722
|
Q15629,P35658,Q9Y5J9,Q9NS69,Q8N1F7,Q9BTX1,Q99595,P49792,Q5JVF3,P12270,Q8TD16,Q8NFH4,O75381,Q9Y5J7,O75694,Q9P2E9,Q9BVL2,Q9BVV7,Q12769
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
523,3,398,7,541,542,22,288,163,293,343,226,99,377,599,506,504,641,495
|
2260,1267,1316,99,599,293,3,1235,1456,288,1546,738,905,2530,949,2531,1849,495,523,1703,163,914,685,541,226,1659,343,1385,777,1102,779,1306,639,22,542,504,641,926,2078,7,506,1759,1481,377,398
|
-0.7461118187735932,-0.021383766664227755,-0.05073464252917762,1.9552468158064782,0.4782294385308354,1.0012473661035215,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,-0.20023841286057453,0.3446320422674998,0.2071618461975449,-1.1716755310485276,0.1791846335137533,-1.1716755310485276,-0.385979494061243,0.6081511143176388,0.5824518687603596,-0.2922176920491657,1.4285407486745718,0.2071618461975449,0.39852436325326,0.5566115286243463,1.1860066448125965,-0.26136298554392196,0.9060329793006716,-0.08026602431198727,0.31745440163525057,0.09425478550483424,0.31745440163525057,-0.021383766664227755,0.45181010850325676,3.4500635955114625,0.5566115286243463,0.6081511143176388,0.45181010850325676,0.2071618461975449,-0.5463883460250468,4.418247982374554,0.6081511143176388,-0.3232704296671488,-0.1398785959133766,0.8333224319696179,0.784211761763469
| 2,702
|
Abnormal metatarsal morphology
| 8
| 20
| 2.276845
| 0.022795
|
Q08AM6,P08236,O96028,P31749,Q15392,Q03252,P50542,O43505
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,258,75,145,117,338,365,362
|
362,2128,1878,75,258,1733,1081,2052,655,145,365,338,290,424,1899,1796,117,1152,1865,1758
|
0.8333224319696179,-0.6120605797493264,-0.4176406731946431,2.233303018813176,1.0945486200442405,-0.3232704296671488,0.09425478550483424,-0.5463883460250468,0.42524226721919817,1.5346812984581808,0.8333224319696179,0.9060329793006716,1.0247492400647817,0.7345798472794599,-0.4176406731946431,-0.35452356200396523,1.7996013420160522,0.06560596082580177,-0.385979494061243,-0.3232704296671488
| 2,702
|
Positive regulation of cell growth
| 7
| 32
| 2.262905
| 0.023642
|
Q96K76,Q9Y3B8,Q9Y263,Q96PU5,P31749,Q7Z4V5,Q9UJU6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
110,47,177,18,145,247,152
|
827,668,1961,477,649,1034,145,1414,2511,607,1326,1787,2064,1327,1329,873,1508,279,813,1428,430,247,1948,110,18,2250,152,1626,596,177,47,1020
|
0.26262791247117023,0.39852436325326,-0.48158877982782056,0.6337106835947478,0.42524226721919817,0.12273293000494902,1.5346812984581808,-0.1099799759281711,-1.1347798177249695,0.4782294385308354,-0.05073464252917762,-0.35452356200396523,-0.5463883460250468,-0.05073464252917762,-0.05073464252917762,0.2349756872773074,-0.1699640181909275,1.0481326767167887,0.29012025009768083,-0.1099799759281711,0.7345798472794599,1.1405038133141903,-0.449509590099947,1.8780952360684287,3.7137574279815024,-0.7122535027473694,1.5136495000737895,-0.23070398700916023,0.504501785431343,1.363654540627114,2.6449460890363556,0.15104226553426064
| 2,702
|
K Homology domain, type 1 superfamily [IPR036612]
| 10
| 23
| 2.261081
| 0.023754
|
Q9Y2W6,P51116,Q92945,Q96AE4,Q07666,P61978,Q9Y6M1,Q9NQT5,Q13868,P51114
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
201,196,265,272,270,153,385,59,279,289
|
792,289,196,1936,153,1141,270,1333,279,1904,2573,1853,2365,1661,265,272,445,1519,59,2292,1393,201,385
|
0.29012025009768083,1.0247492400647817,1.2756876781734239,-0.449509590099947,1.4925203872541544,0.06560596082580177,1.0713987752533087,-0.05073464252917762,1.0481326767167887,-0.4176406731946431,-1.2840336152236627,-0.385979494061243,-0.8491105936663824,-0.26136298554392196,1.0945486200442405,1.0713987752533087,0.7095652084505555,-0.1699640181909275,2.4094934860042883,-0.7461118187735932,-0.08026602431198727,1.2756876781734239,0.8088316185366753
| 2,702
|
Mitochondrion organization
| 34
| 157
| 2.256512
| 0.024039
|
Q9Y5J9,O75153,Q9NS69,P55786,P09874,P31749,Q99595,Q7L592,O95831,O96000,P14406,O14737,O43676,O00429,Q9NUQ9,Q7Z406,Q9Y3B8,P02545,Q6DKK2,Q96A26,P45880,Q13505,Q9Y2R0,Q9NX63,Q16706,Q5JRX3,Q9Y5J7,P21796,Q9UDX5,Q15149,Q15070,Q69YU5,P50542,Q9BUK6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
398,5,7,13,14,145,22,280,26,400,30,160,162,285,302,173,47,178,53,332,195,328,215,214,355,239,377,232,375,371,116,246,365,126
|
896,2420,728,285,160,1267,1316,162,2455,571,5,1534,2003,1352,490,2164,1535,649,701,1317,2659,1966,971,1878,1355,1126,26,400,1879,178,2356,1229,2677,529,2372,1129,2049,14,2006,1080,2554,30,1132,1639,232,2134,2056,1840,2443,1689,1033,145,1690,2360,2374,1596,2173,2338,2557,195,976,2060,2241,365,580,2137,978,2309,13,1366,1188,2671,872,494,582,328,496,116,371,473,743,2655,355,2107,2547,662,1703,2022,239,2363,246,53,2313,1653,280,173,1517,1910,1704,843,2148,1948,431,1055,2248,2315,955,2365,1249,332,922,1108,2073,782,2623,1109,22,1811,2502,1995,447,1619,2516,126,851,641,2319,2414,2469,887,1622,524,2036,7,1170,302,690,2117,214,1215,1012,1822,375,485,1669,693,1874,215,2258,1579,47,597,1960,377,398,1400,727
|
0.2071618461975449,-0.9543108287183288,0.3446320422674998,1.0247492400647817,1.4285407486745718,-0.021383766664227755,-0.05073464252917762,1.4285407486745718,-1.0257109093739025,0.504501785431343,4.720152240851799,-0.20023841286057453,-0.5138808228281478,-0.08026602431198727,0.6081511143176388,-0.6452307866220199,-0.20023841286057453,0.42524226721919817,0.3716548214149085,-0.05073464252917762,-1.929913063783283,-0.48158877982782056,0.15104226553426064,-0.4176406731946431,-0.08026602431198727,0.06560596082580177,3.3258692872450646,0.7594615984524137,-0.4176406731946431,1.341820214976906,-0.8491105936663824,0.007788633325283703,-2.2865857970685295,0.5566115286243463,-0.8839284596697314,0.06560596082580177,-0.5463883460250468,3.9740289947398435,-0.5138808228281478,0.09425478550483424,-1.246298549886792,3.169031630211791,0.06560596082580177,-0.26136298554392196,1.1633112587408174,-0.6120605797493264,-0.5463883460250468,-0.385979494061243,-0.9898819580382101,-0.2922176920491657,0.12273293000494902,1.5346812984581808,-0.2922176920491657,-0.8491105936663824,-0.8839284596697314,-0.23070398700916023,-0.6452307866220199,-0.8145372938985567,-1.246298549886792,1.2756876781734239,0.15104226553426064,-0.5463883460250468,-0.7122535027473694,0.8333224319696179,0.504501785431343,-0.6120605797493264,0.15104226553426064,-0.780205401999509,3.9860302897388693,-0.08026602431198727,0.036784554335826614,-2.149901662757291,0.2349756872773074,0.6081511143176388,0.504501785431343,0.9300199004069388,0.6081511143176388,1.7996013420160522,0.8333224319696179,0.6591319741805618,0.3446320422674998,-1.8445118508373655,0.8576854474690445,-0.5791140239235776,-1.208847161551696,0.42524226721919817,-0.2922176920491657,-0.5138808228281478,1.1633112587408174,-0.8491105936663824,1.1405038133141903,2.4439076160408386,-0.780205401999509,-0.26136298554392196,1.0481326767167887,1.363654540627114,-0.1699640181909275,-0.4176406731946431,-0.2922176920491657,0.26262791247117023,-0.6120605797493264,-0.449509590099947,0.7345798472794599,0.12273293000494902,-0.7122535027473694,-0.780205401999509,0.1791846335137533,-0.8491105936663824,0.007788633325283703,0.9300199004069388,0.2071618461975449,0.09425478550483424,-0.5463883460250468,0.31745440163525057,-1.516631141683355,0.09425478550483424,3.4500635955114625,-0.35452356200396523,-1.0981562573910337,-0.48158877982782056,0.7095652084505555,-0.23070398700916023,-1.1347798177249695,1.6995293541371095,0.26262791247117023,0.45181010850325676,-0.780205401999509,-0.9189941109407576,-1.0257109093739025,0.2349756872773074,-0.23070398700916023,0.5824518687603596,-0.5138808228281478,4.418247982374554,0.06560596082580177,1.0012473661035215,0.39852436325326,-0.5791140239235776,1.231065281813778,0.036784554335826614,0.15104226553426064,-0.35452356200396523,0.8333224319696179,0.6337106835947478,-0.26136298554392196,0.39852436325326,-0.385979494061243,1.231065281813778,-0.7122535027473694,-0.20023841286057453,2.6449460890363556,0.504501785431343,-0.449509590099947,0.8333224319696179,0.784211761763469,-0.08026602431198727,0.3716548214149085
| 2,702
|
Transporter activity
| 29
| 161
| 2.244543
| 0.024797
|
P25705,Q70HW3,Q9NS69,Q6N075,O43772,Q6NT16,Q99595,Q9BQT8,O15439,Q9Y487,Q8IXU6,O43676,P21281,O15173,P00403,Q8NEW0,Q9HD20,Q13423,P41440,P08183,P45880,Q9H2D1,P53985,Q99829,Q9H4L5,P21796,P38435,Q93050,P51991
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
252,6,7,134,9,19,22,23,277,156,33,162,287,286,165,300,190,187,67,70,195,73,100,240,107,232,109,114,244
|
1530,728,1487,1219,1631,1267,306,286,277,162,2455,1124,9,2085,572,2003,1352,1535,2331,1679,1022,1317,2659,1966,971,2130,1878,1355,2332,400,1879,165,1229,1681,1682,1127,2372,863,1407,1281,70,1775,1969,1282,2693,2554,2397,800,1451,1029,2236,2358,1030,287,1590,232,675,2053,2093,252,1287,2056,1033,2306,353,1975,1036,109,1843,67,195,2012,1693,2100,2637,2617,1740,1891,978,244,1546,100,2341,1292,632,949,2638,2183,2380,2480,2461,2382,187,1194,497,473,2221,2107,2547,1375,134,19,988,1906,877,6,1654,33,2641,459,2576,992,2315,300,1706,2684,372,2596,114,2114,2438,1206,1063,1520,959,639,22,1995,748,240,23,2152,1346,2539,2349,1255,73,590,2632,107,2291,1574,190,7,1012,1396,2154,754,1397,855,2644,667,1628,2578,156,398,548,936,2206,1441,727
|
-0.20023841286057453,0.3446320422674998,-0.1699640181909275,0.007788633325283703,-0.26136298554392196,-0.021383766664227755,0.9776259405477873,1.0247492400647817,1.0481326767167887,1.4285407486745718,-1.0257109093739025,0.06560596082580177,4.1389954392444945,-0.5791140239235776,0.504501785431343,-0.5138808228281478,-0.08026602431198727,-0.20023841286057453,-0.8145372938985567,-0.2922176920491657,0.12273293000494902,-0.05073464252917762,-1.929913063783283,-0.48158877982782056,0.15104226553426064,-0.6120605797493264,-0.4176406731946431,-0.08026602431198727,-0.8145372938985567,0.7594615984524137,-0.4176406731946431,1.407013911282315,0.007788633325283703,-0.2922176920491657,-0.2922176920491657,0.06560596082580177,-0.8839284596697314,0.2349756872773074,-0.1099799759281711,-0.021383766664227755,2.2868970423085044,-0.35452356200396523,-0.48158877982782056,-0.021383766664227755,-3.959608434173559,-1.246298549886792,-0.9189941109407576,0.29012025009768083,-0.1398785959133766,0.12273293000494902,-0.7122535027473694,-0.8491105936663824,0.12273293000494902,1.0247492400647817,-0.23070398700916023,1.1633112587408174,0.39852436325326,-0.5463883460250468,-0.5791140239235776,1.1175832808973218,-0.021383766664227755,-0.5463883460250468,0.12273293000494902,-0.780205401999509,0.8576854474690445,-0.48158877982782056,0.12273293000494902,1.8780952360684287,-0.385979494061243,2.339853291567594,1.2756876781734239,-0.5138808228281478,-0.2922176920491657,-0.5791140239235776,-1.6779093391999742,-1.516631141683355,-0.3232704296671488,-0.4176406731946431,0.15104226553426064,1.1405038133141903,-0.20023841286057453,1.9552468158064782,-0.8145372938985567,-0.021383766664227755,0.45181010850325676,0.1791846335137533,-1.6779093391999742,-0.6452307866220199,-0.8839284596697314,-1.0618011603301436,-1.0257109093739025,-0.8839284596697314,1.2978377151319078,0.036784554335826614,0.6081511143176388,0.6591319741805618,-0.6786274687643568,-0.5791140239235776,-1.208847161551696,-0.08026602431198727,1.6178517102360863,3.6493512824571805,0.15104226553426064,-0.4176406731946431,0.2349756872773074,4.700030074598367,-0.26136298554392196,3.08101788485959,-1.6779093391999742,0.6844163633500198,-1.2840336152236627,0.15104226553426064,-0.780205401999509,1.0012473661035215,-0.2922176920491657,-2.8726852179118376,0.8333224319696179,-1.3989812878170513,1.819353019865366,-0.5791140239235776,-0.9543108287183288,0.036784554335826614,0.12273293000494902,-0.1699640181909275,0.1791846335137533,0.45181010850325676,3.4500635955114625,-0.48158877982782056,0.3446320422674998,1.1633112587408174,3.4500635955114625,-0.6120605797493264,-0.05073464252917762,-1.1716755310485276,-0.8145372938985567,0.007788633325283703,2.2691039308231553,0.504501785431343,-1.5564687430126587,1.8975073051504956,-0.7461118187735932,-0.20023841286057453,1.2978377151319078,4.418247982374554,0.15104226553426064,-0.08026602431198727,-0.6120605797493264,0.3446320422674998,-0.08026602431198727,0.26262791247117023,-1.6779093391999742,0.42524226721919817,-0.23070398700916023,-1.2840336152236627,1.4925203872541544,0.784211761763469,0.5566115286243463,0.2071618461975449,-0.6452307866220199,-0.1099799759281711,0.3716548214149085
| 2,702
|
Negative regulation of mrna splicing via spliceosome
| 7
| 15
| 2.240856
| 0.025035
|
P22626,Q13242,P98175,O75494,P61978,P38159,Q16629
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
159,263,310,182,153,91,428
|
2230,182,159,1183,1453,91,153,310,1242,909,1988,263,520,1945,428
|
-0.7122535027473694,1.319881581600934,1.4499668634992937,0.036784554335826614,-0.1398785959133766,2.031097928717653,1.4925203872541544,0.9776259405477873,0.007788633325283703,0.2071618461975449,-0.48158877982782056,1.0945486200442405,0.5824518687603596,-0.449509590099947,0.7345798472794599
| 2,702
|
Ciliopathies
| 8
| 16
| 2.239845
| 0.025101
|
Q9NQH7,O43924,Q10713,Q7Z4L5,Q9BW83,Q13432,P49454,Q15555
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
357,101,582,105,665,83,364,318
|
101,1353,1780,364,1507,582,83,318,105,1559,1561,1387,1810,665,357,692
|
1.936082441353349,-0.08026602431198727,-0.35452356200396523,0.8333224319696179,-0.1699640181909275,0.504501785431343,2.1425231720053195,0.9538838337472978,1.9168361544314048,-0.20023841286057453,-0.20023841286057453,-0.08026602431198727,-0.35452356200396523,0.42524226721919817,0.8576854474690445,0.39852436325326
| 2,702
|
Actomyosin
| 6
| 23
| 2.234776
| 0.025432
|
P09493,Q7Z406,P06753,P35580,P67936,Q9UJW0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
130,173,229,309,278,127
|
895,2260,898,2128,229,130,1178,316,309,278,1051,1428,1946,173,778,747,1663,618,1253,1392,1116,1480,127
|
0.2071618461975449,-0.7461118187735932,0.2071618461975449,-0.6120605797493264,1.1633112587408174,1.6588740220805571,0.036784554335826614,0.9538838337472978,0.9776259405477873,1.0481326767167887,0.12273293000494902,-0.1099799759281711,-0.449509590099947,1.363654540627114,0.31745440163525057,0.3446320422674998,-0.26136298554392196,0.4782294385308354,0.007788633325283703,-0.08026602431198727,0.09425478550483424,-0.1398785959133766,1.6792471805421514
| 2,702
|
Mitotic cytokinesis
| 11
| 29
| 2.223945
| 0.026152
|
Q01082,Q13464,Q14141,P16949,O14578,Q9H0H5,Q6DKK2,P35580,Q13432,Q9Y5X1,Q53EZ4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
535,521,141,416,171,115,53,309,83,88,383
|
171,969,1354,862,671,416,1685,309,1780,1235,1892,535,1550,874,83,521,141,383,53,778,2411,1866,115,1169,1011,623,2258,1722,88
|
1.363654540627114,0.15104226553426064,-0.08026602431198727,0.2349756872773074,0.39852436325326,0.7345798472794599,-0.2922176920491657,0.9776259405477873,-0.35452356200396523,0.007788633325283703,-0.4176406731946431,0.5566115286243463,-0.20023841286057453,0.2349756872773074,2.1425231720053195,0.5824518687603596,1.5556166081262797,0.8088316185366753,2.4439076160408386,0.31745440163525057,-0.9189941109407576,-0.385979494061243,1.819353019865366,0.06560596082580177,0.15104226553426064,0.4782294385308354,-0.7122535027473694,-0.2922176920491657,2.087156944238238
| 2,702
|
Apoptotic cleavage of cellular proteins
| 8
| 18
| 2.216466
| 0.02666
|
Q14790,Q13464,P15924,Q15149,P20700,P08670,P02545,Q9UJU6
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
329,521,326,371,418,49,178,152
|
178,49,326,418,1234,577,2137,1139,1192,521,711,1900,329,371,1069,1825,152,856
|
1.341820214976906,2.511943158877311,0.9300199004069388,0.7345798472794599,0.007788633325283703,0.504501785431343,-0.6120605797493264,0.06560596082580177,0.036784554335826614,0.5824518687603596,0.3716548214149085,-0.4176406731946431,0.9300199004069388,0.8333224319696179,0.12273293000494902,-0.35452356200396523,1.5136495000737895,0.26262791247117023
| 2,702
|
Cellular response to molecule of bacterial origin
| 7
| 27
| 2.208178
| 0.027232
|
Q9NUQ9,O43823,Q9Y263,P08670,P31749,P14174,Q86U42
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
302,106,177,49,145,56,254
|
106,49,2167,1492,2090,56,833,653,655,1033,145,1412,913,1376,2282,2023,841,254,2193,1911,1658,372,921,1308,302,1011,177
|
1.8975073051504956,2.511943158877311,-0.6452307866220199,-0.1699640181909275,-0.5791140239235776,2.4094934860042883,0.26262791247117023,0.42524226721919817,0.42524226721919817,0.12273293000494902,1.5346812984581808,-0.1099799759281711,0.2071618461975449,-0.08026602431198727,-0.7461118187735932,-0.5138808228281478,0.26262791247117023,1.1175832808973218,-0.6452307866220199,-0.4176406731946431,-0.26136298554392196,0.8333224319696179,0.2071618461975449,-0.021383766664227755,1.0012473661035215,0.15104226553426064,1.363654540627114
| 2,702
|
Proximal amyotrophy
| 10
| 14
| 2.198423
| 0.027919
|
O14979,Q13642,Q14204,Q16637,Q92734,P50402,P35637,P02545,Q9BQP7,P07196
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,609,661,170,301,295,81,178,447,185
|
128,178,185,81,295,2016,609,661,170,686,301,447,2199,791
|
1.6588740220805571,1.341820214976906,1.2978377151319078,2.160827351832918,1.0012473661035215,-0.5138808228281478,0.4782294385308354,0.42524226721919817,1.3853854720918395,0.39852436325326,1.0012473661035215,0.7095652084505555,-0.6452307866220199,0.31745440163525057
| 2,702
|
Severe muscular hypotonia
| 9
| 24
| 2.197013
| 0.028019
|
O75381,Q9NWM8,Q01105,Q8TD16,P06753,P02545,P50542,P40855,O95831
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,135,169,343,229,178,365,337,26
|
362,99,2331,26,178,229,1885,337,365,767,1505,169,1330,2219,661,1155,2365,343,1058,2366,1308,2348,2414,135
|
0.8333224319696179,1.9552468158064782,-0.8145372938985567,3.3258692872450646,1.341820214976906,1.1633112587408174,-0.4176406731946431,0.9060329793006716,0.8333224319696179,0.31745440163525057,-0.1699640181909275,1.3853854720918395,-0.05073464252917762,-0.6786274687643568,0.42524226721919817,0.06560596082580177,-0.8491105936663824,0.9060329793006716,0.12273293000494902,-0.8491105936663824,-0.021383766664227755,-0.8145372938985567,-0.9189941109407576,1.6178517102360863
| 2,702
|
Thyroid cancer
| 7
| 10
| 2.183274
| 0.029016
|
Q16204,Q92734,P12270,P28482,P06753,P27361,P04637
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
197,301,293,655,229,653,529
|
529,229,293,653,655,1234,706,1241,197,301
|
0.5566115286243463,1.1633112587408174,1.0012473661035215,0.42524226721919817,0.42524226721919817,0.007788633325283703,0.3716548214149085,0.007788633325283703,1.2756876781734239,1.0012473661035215
| 2,702
|
Somatic mutation
| 7
| 34
| 2.177365
| 0.029453
|
P35658,Q01844,P00813,P31749,O75874,Q92804,P30154
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,133,42,145,54,90,186
|
896,2523,1490,699,648,54,42,529,702,1492,674,1970,1359,2054,186,145,1234,2360,3,974,948,441,1984,133,1043,2561,1851,1744,329,537,2282,219,90,1001
|
0.2071618461975449,-1.1716755310485276,-0.1699640181909275,0.3716548214149085,0.42524226721919817,2.4267339760166293,2.6938037281589335,0.5566115286243463,0.3716548214149085,-0.1699640181909275,0.39852436325326,-0.48158877982782056,-0.08026602431198727,-0.5463883460250468,1.2978377151319078,1.5346812984581808,0.007788633325283703,-0.8491105936663824,4.779930332154013,0.15104226553426064,0.1791846335137533,0.7095652084505555,-0.48158877982782056,1.6178517102360863,0.12273293000494902,-1.246298549886792,-0.385979494061243,-0.3232704296671488,0.9300199004069388,0.5566115286243463,-0.7461118187735932,1.208590985594112,2.049862232695574,0.15104226553426064
| 2,702
|
Arthralgia
| 7
| 28
| 2.168369
| 0.030131
|
P28070,Q96HY6,P02545,Q03252,O15460,P14174,Q9NZ08
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
10,312,178,338,55,56,221
|
896,55,2329,178,1967,56,1133,703,1885,10,1234,1135,1544,1786,1938,1422,1895,338,769,406,2482,1303,312,221,1480,1261,568,2328
|
0.2071618461975449,2.4094934860042883,-0.8145372938985567,1.341820214976906,-0.48158877982782056,2.4094934860042883,0.06560596082580177,0.3716548214149085,-0.4176406731946431,4.127425604581578,0.007788633325283703,0.06560596082580177,-0.20023841286057453,-0.35452356200396523,-0.449509590099947,-0.1099799759281711,-0.4176406731946431,0.9060329793006716,0.31745440163525057,0.7594615984524137,-1.0618011603301436,-0.021383766664227755,0.9776259405477873,1.208590985594112,-0.1398785959133766,0.007788633325283703,0.5306286544959777,-0.780205401999509
| 2,702
|
Metatarsus adductus
| 6
| 12
| 2.163079
| 0.030535
|
Q08AM6,P08236,O96028,Q15392,P50542,Q03252
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,258,75,117,365,338
|
1878,75,258,655,365,338,290,424,1899,117,1152,1758
|
-0.4176406731946431,2.233303018813176,1.0945486200442405,0.42524226721919817,0.8333224319696179,0.9060329793006716,1.0247492400647817,0.7345798472794599,-0.4176406731946431,1.7996013420160522,0.06560596082580177,-0.3232704296671488
| 2,702
|
Abnormal enchondral ossification
| 10
| 23
| 2.150349
| 0.031528
|
Q08AM6,Q14739,P08236,O75381,O96028,P38435,Q96HY6,P50542,P40855,O00116
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,457,258,99,75,109,312,365,337,334
|
334,2128,99,1878,75,258,1733,2052,1596,109,337,365,2215,290,1899,457,1796,2246,1561,312,1758,485,936
|
0.9060329793006716,-0.6120605797493264,1.9552468158064782,-0.4176406731946431,2.233303018813176,1.0945486200442405,-0.3232704296671488,-0.5463883460250468,-0.23070398700916023,1.8780952360684287,0.9060329793006716,0.8333224319696179,-0.6786274687643568,1.0247492400647817,-0.4176406731946431,0.6844163633500198,-0.35452356200396523,-0.7122535027473694,-0.20023841286057453,0.9776259405477873,-0.3232704296671488,0.6337106835947478,0.2071618461975449
| 2,702
|
Abnormal epiphyseal ossification
| 8
| 14
| 2.144052
| 0.032029
|
P08236,Q14739,O75381,P38435,Q96HY6,P50542,P40855,O00116
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,457,99,109,312,365,337,334
|
334,2128,99,258,1733,109,337,365,457,1796,2246,312,1758,485
|
0.9060329793006716,-0.6120605797493264,1.9552468158064782,1.0945486200442405,-0.3232704296671488,1.8780952360684287,0.9060329793006716,0.8333224319696179,0.6844163633500198,-0.35452356200396523,-0.7122535027473694,0.9776259405477873,-0.3232704296671488,0.6337106835947478
| 2,702
|
Mrna binding
| 50
| 162
| 2.141532
| 0.032231
|
O43390,O75153,Q13247,P18124,Q99729,Q92945,Q96AE4,Q07666,Q9UN86,Q86V81,Q8IY67,P61978,P04637,P51114,P22626,P11940,Q13151,Q01085,Q96MU7,Q96PK6,P12270,Q71RC2,P17844,P35580,O75150,Q96I24,P07910,Q9P2K5,P51116,P16989,P00374,P52272,O95453,P52756,P35637,Q9BWF3,Q5VTR2,Q07955,Q13310,Q92804,P38159,Q8NDT2,Q14103,P62995,O60506,Q9BPZ3,P34896,P51991,P67809,Q9Y6M1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
129,5,520,516,138,265,272,270,284,408,540,153,529,289,159,401,536,297,560,176,293,556,417,309,549,445,315,593,196,72,202,454,573,455,81,212,211,339,470,90,91,482,237,235,111,113,243,244,121,385
|
1122,1401,792,668,1445,129,2044,1830,2163,2127,111,549,1533,5,648,2086,2422,573,202,529,672,1280,315,1832,1833,401,293,1493,864,2007,72,417,516,575,945,1931,159,704,2267,1453,2054,2097,1541,243,1289,309,81,91,1497,2594,1363,2375,2136,2240,1645,289,196,1936,2376,244,454,455,2062,1546,1847,2310,869,2216,153,2639,1984,1893,1293,235,121,1327,1985,1141,1088,297,1329,873,1242,270,339,909,910,2312,1508,2496,1294,980,1295,811,536,680,520,1147,470,875,237,1553,1945,1904,2573,2281,985,1853,1151,1374,682,211,990,556,408,540,746,1163,482,2027,2070,2071,90,1753,265,272,957,817,445,560,176,1519,848,2196,2623,138,113,1996,212,2151,1254,1064,2676,723,1919,1573,752,1010,1393,593,1759,1999,284,2324,1761,2122,1629,1440,1630,2683,1121,385
|
0.06560596082580177,-0.1099799759281711,0.29012025009768083,0.39852436325326,-0.1398785959133766,1.6588740220805571,-0.5463883460250468,-0.385979494061243,-0.6452307866220199,-0.6120605797493264,1.8585992820751742,0.5306286544959777,-0.20023841286057453,4.720152240851799,0.42524226721919817,-0.5791140239235776,-0.9543108287183288,0.504501785431343,1.2534305210935053,0.5566115286243463,0.39852436325326,-0.021383766664227755,0.9538838337472978,-0.385979494061243,-0.385979494061243,0.7594615984524137,1.0012473661035215,-0.1699640181909275,0.2349756872773074,-0.5138808228281478,2.2691039308231553,0.7345798472794599,0.5824518687603596,0.504501785431343,0.1791846335137533,-0.449509590099947,1.4499668634992937,0.3716548214149085,-0.7461118187735932,-0.1398785959133766,-0.5463883460250468,-0.5791140239235776,-0.20023841286057453,1.1405038133141903,-0.021383766664227755,0.9776259405477873,2.160827351832918,2.031097928717653,-0.1699640181909275,-1.3989812878170513,-0.08026602431198727,-0.8839284596697314,-0.6120605797493264,-0.7122535027473694,-0.26136298554392196,1.0247492400647817,1.2756876781734239,-0.449509590099947,-0.8839284596697314,1.1405038133141903,0.6844163633500198,0.6844163633500198,-0.5463883460250468,-0.20023841286057453,-0.385979494061243,-0.780205401999509,0.2349756872773074,-0.6786274687643568,1.4925203872541544,-1.6779093391999742,-0.48158877982782056,-0.4176406731946431,-0.021383766664227755,1.1633112587408174,1.7197212915351867,-0.05073464252917762,-0.48158877982782056,0.06560596082580177,0.09425478550483424,1.0012473661035215,-0.05073464252917762,0.2349756872773074,0.007788633325283703,1.0713987752533087,0.9060329793006716,0.2071618461975449,0.2071618461975449,-0.780205401999509,-0.1699640181909275,-1.0981562573910337,-0.021383766664227755,0.15104226553426064,-0.021383766664227755,0.29012025009768083,0.5566115286243463,0.39852436325326,0.5824518687603596,0.06560596082580177,0.6591319741805618,0.2349756872773074,1.1633112587408174,-0.20023841286057453,-0.449509590099947,-0.4176406731946431,-1.2840336152236627,-0.7461118187735932,0.15104226553426064,-0.385979494061243,0.06560596082580177,-0.08026602431198727,0.39852436325326,1.231065281813778,0.15104226553426064,0.5306286544959777,0.7594615984524137,0.5566115286243463,0.3446320422674998,0.06560596082580177,0.6337106835947478,-0.5138808228281478,-0.5463883460250468,-0.5463883460250468,2.049862232695574,-0.3232704296671488,1.0945486200442405,1.0713987752533087,0.1791846335137533,0.29012025009768083,0.7095652084505555,0.5306286544959777,1.363654540627114,-0.1699640181909275,0.26262791247117023,-0.6452307866220199,-1.516631141683355,1.5764562446123624,1.8390187702748255,-0.48158877982782056,1.231065281813778,-0.6120605797493264,0.007788633325283703,0.12273293000494902,-2.195059359857069,0.3716548214149085,-0.4176406731946431,-0.20023841286057453,0.3446320422674998,0.15104226553426064,-0.08026602431198727,0.504501785431343,-0.3232704296671488,-0.48158877982782056,1.0481326767167887,-0.780205401999509,-0.3232704296671488,-0.5791140239235776,-0.23070398700916023,-0.1099799759281711,-0.23070398700916023,-2.8212370776890143,0.09425478550483424,0.8088316185366753
| 2,702
|
Organic cyclic compound catabolic process
| 43
| 150
| 2.141495
| 0.032234
|
Q9H773,P62312,Q9Y2W1,Q9H814,Q9UKD2,Q92945,Q99729,P31749,O95831,Q13868,Q969T7,P51114,P11940,Q13126,Q5JVF3,Q6Y7W6,P00813,Q9BQG2,Q08J23,P08670,P17844,P98175,P16930,Q9NZN8,Q9NQT5,P07910,Q9HCE1,P51116,Q5RKV6,P16989,P52272,P30519,P35637,Q13310,Q92804,Q9NRN7,Q6NZY4,Q9Y3Z3,P33527,Q14103,Q8WTV0,O60506,P67809
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,261,396,394,395,265,138,145,26,279,158,289,401,32,163,299,42,45,424,49,417,310,179,449,59,315,199,196,330,72,454,80,81,470,90,220,349,486,353,237,372,111,121
|
1581,2000,2679,2081,2296,1676,477,2263,111,2002,528,796,573,26,2423,2210,42,1280,702,315,49,797,2049,1130,1408,401,2091,2303,179,72,417,551,2429,2134,656,80,145,1594,353,81,2701,1497,2058,804,1934,552,289,196,454,2062,1040,1938,739,261,2460,1293,121,1240,310,1088,2243,1460,1190,873,910,424,1508,1294,32,811,536,470,521,279,237,950,984,1945,2650,1151,913,1905,163,330,1467,349,2110,613,684,1558,990,299,1652,1747,1380,1158,2314,539,1993,1948,1163,2365,372,2071,90,1753,921,265,158,1662,1708,817,1344,138,2198,784,45,2348,723,2288,2468,2319,724,928,1919,1,394,1007,2077,822,1816,199,59,220,964,2202,1393,449,593,1873,395,2120,2551,1528,2122,396,2652,486,1121,1020
|
-0.23070398700916023,-0.5138808228281478,-2.3797721160822345,-0.5791140239235776,-0.780205401999509,-0.2922176920491657,0.6337106835947478,-0.7461118187735932,1.8585992820751742,-0.5138808228281478,0.5566115286243463,0.29012025009768083,0.504501785431343,3.3258692872450646,-0.9543108287183288,-0.6786274687643568,2.6938037281589335,-0.021383766664227755,0.3716548214149085,0.9538838337472978,2.511943158877311,0.29012025009768083,-0.5463883460250468,0.06560596082580177,-0.1099799759281711,0.7594615984524137,-0.5791140239235776,-0.780205401999509,1.341820214976906,2.2691039308231553,0.7345798472794599,0.5306286544959777,-0.9543108287183288,-0.6120605797493264,0.42524226721919817,2.160827351832918,1.5346812984581808,-0.23070398700916023,0.8576854474690445,2.160827351832918,-12.168317660218063,-0.1699640181909275,-0.5463883460250468,0.29012025009768083,-0.449509590099947,0.5306286544959777,1.0247492400647817,1.2756876781734239,0.6844163633500198,-0.5463883460250468,0.12273293000494902,-0.449509590099947,0.3446320422674998,1.0945486200442405,-1.0257109093739025,-0.021383766664227755,1.7197212915351867,0.007788633325283703,0.9776259405477873,0.09425478550483424,-0.7122535027473694,-0.1398785959133766,0.036784554335826614,0.2349756872773074,0.2071618461975449,0.7345798472794599,-0.1699640181909275,-0.021383766664227755,3.08101788485959,0.29012025009768083,0.5566115286243463,0.6591319741805618,0.5824518687603596,1.0481326767167887,1.1633112587408174,0.1791846335137533,0.15104226553426064,-0.449509590099947,-1.7605248468578005,0.06560596082580177,0.2071618461975449,-0.4176406731946431,1.4285407486745718,0.9300199004069388,-0.1398785959133766,0.8819218929788717,-0.5791140239235776,0.4782294385308354,0.39852436325326,-0.20023841286057453,0.15104226553426064,1.0012473661035215,-0.26136298554392196,-0.3232704296671488,-0.08026602431198727,0.06560596082580177,-0.780205401999509,0.5566115286243463,-0.48158877982782056,-0.449509590099947,0.06560596082580177,-0.8491105936663824,0.8333224319696179,-0.5463883460250468,2.049862232695574,-0.3232704296671488,0.2071618461975449,1.0945486200442405,1.4712931239277853,-0.26136298554392196,-0.2922176920491657,0.29012025009768083,-0.05073464252917762,1.5764562446123624,-0.6452307866220199,0.31745440163525057,2.6449460890363556,-0.8145372938985567,0.3716548214149085,-0.7461118187735932,-1.0257109093739025,-0.780205401999509,0.3716548214149085,0.2071618461975449,-0.4176406731946431,4.906515029198439,0.784211761763469,0.15104226553426064,-0.5463883460250468,0.29012025009768083,-0.35452356200396523,1.2756876781734239,2.4094934860042883,1.208590985594112,0.1791846335137533,-0.6452307866220199,-0.08026602431198727,0.7095652084505555,0.504501785431343,-0.385979494061243,0.784211761763469,-0.5791140239235776,-1.208847161551696,-0.1699640181909275,-0.5791140239235776,0.784211761763469,-1.8023442870653426,0.6337106835947478,0.09425478550483424,0.15104226553426064
| 2,702
|
Pain
| 61
| 146
| 2.139148
| 0.032424
|
Q12769,Q01844,Q70HW3,P28070,P50995,P23786,Q8N1F7,Q14108,O75533,P31749,O14936,P48735,Q15056,Q14980,P04637,P22626,Q8WXH0,Q15645,Q01082,O00429,Q9Y2U8,Q15165,P50402,Q14203,P21964,P07602,P20700,Q96HY6,P02545,O75874,O15460,P14174,Q13423,P52701,O75844,Q14739,Q9H3U1,P42892,P06748,O60313,O75477,Q9NR77,O14802,P35637,P43243,P19447,Q03252,Q92804,Q8WX93,Q9NZ08,Q8NFH4,Q9UGP8,Q13642,P09651,P14314,P53680,Q8WUM0,Q14566,P43246,Q9BUK6,Q13043
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
495,133,6,10,390,267,541,147,648,145,149,24,406,537,529,159,686,681,535,285,568,43,295,425,551,673,418,312,178,54,55,56,187,441,314,457,726,194,702,571,323,344,451,81,578,703,338,90,747,221,226,754,609,604,731,736,777,636,630,126,519
|
896,285,451,149,1531,1488,55,898,2329,571,323,648,314,54,2131,1772,2211,178,1229,2441,529,1967,702,673,2587,1321,1927,604,1733,1683,2654,1636,2554,56,731,1133,1540,703,418,1359,1322,551,1884,1885,159,267,2054,10,2305,1974,145,1234,1135,81,866,2009,1084,2580,1933,194,578,630,948,24,1544,2099,295,977,390,1891,2180,441,1786,736,1418,2271,1938,2340,905,1698,2215,1422,535,1895,133,2461,338,1043,1896,1792,495,2561,519,811,1462,187,769,609,147,425,1426,636,2018,457,537,2019,406,43,681,2482,1946,2282,953,6,1098,541,991,1303,226,777,2537,747,686,779,2666,90,995,1062,312,782,999,2199,126,926,726,887,344,221,1668,2322,754,1480,1261,568,2328,1485
|
0.2071618461975449,1.0247492400647817,0.6844163633500198,1.5136495000737895,-0.20023841286057453,-0.1699640181909275,2.4094934860042883,0.2071618461975449,-0.8145372938985567,0.504501785431343,0.9300199004069388,0.42524226721919817,0.9538838337472978,2.4267339760166293,-0.6120605797493264,-0.35452356200396523,-0.6786274687643568,1.341820214976906,0.007788633325283703,-0.9898819580382101,0.5566115286243463,-0.48158877982782056,0.3716548214149085,0.39852436325326,-1.3603708589860188,-0.05073464252917762,-0.449509590099947,0.4782294385308354,-0.3232704296671488,-0.2922176920491657,-1.8445118508373655,-0.26136298554392196,-1.246298549886792,2.4094934860042883,0.3446320422674998,0.06560596082580177,-0.20023841286057453,0.3716548214149085,0.7345798472794599,-0.08026602431198727,-0.05073464252917762,0.5306286544959777,-0.4176406731946431,-0.4176406731946431,1.4499668634992937,1.0713987752533087,-0.5463883460250468,4.127425604581578,-0.780205401999509,-0.48158877982782056,1.5346812984581808,0.007788633325283703,0.06560596082580177,2.160827351832918,0.2349756872773074,-0.5138808228281478,0.09425478550483424,-1.3220563573737758,-0.449509590099947,1.2756876781734239,0.504501785431343,0.45181010850325676,0.1791846335137533,3.3953101294729233,-0.20023841286057453,-0.5791140239235776,1.0012473661035215,0.15104226553426064,0.784211761763469,-0.4176406731946431,-0.6452307866220199,0.7095652084505555,-0.35452356200396523,0.3446320422674998,-0.1099799759281711,-0.7461118187735932,-0.449509590099947,-0.8145372938985567,0.2071618461975449,-0.2922176920491657,-0.6786274687643568,-0.1099799759281711,0.5566115286243463,-0.4176406731946431,1.6178517102360863,-1.0257109093739025,0.9060329793006716,0.12273293000494902,-0.4176406731946431,-0.35452356200396523,0.6081511143176388,-1.246298549886792,0.5824518687603596,0.29012025009768083,-0.1398785959133766,1.2978377151319078,0.31745440163525057,0.4782294385308354,1.5346812984581808,0.7345798472794599,-0.1099799759281711,0.45181010850325676,-0.5138808228281478,0.6844163633500198,0.5566115286243463,-0.5138808228281478,0.7594615984524137,2.677578161237687,0.39852436325326,-1.0618011603301436,-0.449509590099947,-0.7461118187735932,0.1791846335137533,4.700030074598367,0.09425478550483424,0.5566115286243463,0.15104226553426064,-0.021383766664227755,1.1860066448125965,0.31745440163525057,-1.1716755310485276,0.3446320422674998,0.39852436325326,0.31745440163525057,-2.0607648350784475,2.049862232695574,0.15104226553426064,0.12273293000494902,0.9776259405477873,0.31745440163525057,0.15104226553426064,-0.6452307866220199,1.6995293541371095,0.2071618461975449,0.3716548214149085,0.2349756872773074,0.9060329793006716,1.208590985594112,-0.26136298554392196,-0.780205401999509,0.3446320422674998,-0.1398785959133766,0.007788633325283703,0.5306286544959777,-0.780205401999509,-0.1398785959133766
| 2,702
|
Arthritis
| 15
| 35
| 2.137234
| 0.032579
|
O75844,Q14739,Q9Y2U8,P28070,Q7Z406,P21964,Q14108,Q96HY6,P02545,P50851,P10321,O15460,P14174,Q9NZ08,Q9Y3Z3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
314,457,568,10,173,551,147,312,178,580,492,55,56,221,486
|
896,55,314,2210,178,1229,1967,603,492,2089,56,551,1885,10,1544,580,1891,1786,1418,1646,949,1507,769,147,457,1796,173,991,1303,2666,995,312,221,568,486
|
0.2071618461975449,2.4094934860042883,0.9538838337472978,-0.6786274687643568,1.341820214976906,0.007788633325283703,-0.48158877982782056,0.4782294385308354,0.6081511143176388,-0.5791140239235776,2.4094934860042883,0.5306286544959777,-0.4176406731946431,4.127425604581578,-0.20023841286057453,0.504501785431343,-0.4176406731946431,-0.35452356200396523,-0.1099799759281711,-0.26136298554392196,0.1791846335137533,-0.1699640181909275,0.31745440163525057,1.5346812984581808,0.6844163633500198,-0.35452356200396523,1.363654540627114,0.15104226553426064,-0.021383766664227755,-2.0607648350784475,0.15104226553426064,0.9776259405477873,1.208590985594112,0.5306286544959777,0.6337106835947478
| 2,702
|
Abnormality of long bone morphology
| 46
| 148
| 2.127032
| 0.033417
|
P08236,Q15813,O14936,P48735,Q15056,O95831,Q32P28,Q9Y487,P04637,Q13868,P22626,O75312,Q13126,Q08AM6,Q01082,P21281,Q9Y2U8,Q8N0X7,P00813,Q9BXW9,Q08J23,Q96HY6,Q96AY3,P02545,P98175,O75874,O75718,O75419,O75844,Q14739,O96028,O14802,Q9NR77,Q9UHX1,P40855,O60568,O00116,Q9UG56,O75381,Q6DKJ4,Q7Z4L5,P38435,P37268,P50542,O75431,O75648
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,407,149,24,406,26,27,156,529,279,159,528,32,290,535,287,568,167,42,562,424,312,51,178,310,54,307,414,314,457,75,451,344,345,337,335,334,485,99,480,105,109,112,365,490,491
|
334,896,2261,2610,2662,2083,451,149,1725,2329,1963,335,2002,528,2128,99,414,490,861,491,307,314,54,1878,573,1449,2088,26,1538,75,42,178,529,702,1320,258,2488,604,1733,1492,2660,1588,1081,2556,1685,287,2052,1359,159,2267,2170,655,1842,1135,706,1596,112,109,2173,1497,1976,337,2557,948,2581,1416,1598,24,1364,365,1891,607,2595,1938,2215,1422,1189,310,535,1507,1241,1043,1896,1792,290,424,2219,2640,32,1899,279,951,457,1796,1511,406,2068,2246,407,1152,1854,27,555,480,915,745,1379,2498,1300,105,1517,167,1561,2678,1387,1474,51,2437,312,958,1865,1344,640,1618,2389,562,1521,2250,726,1920,344,753,1716,1010,2079,2321,1758,485,2419,345,1261,1527,1760,568,156,2328,1121,936
|
0.9060329793006716,0.2071618461975449,-0.7461118187735932,-1.477107037869868,-1.9731578815729123,-0.5791140239235776,0.6844163633500198,1.5136495000737895,-0.3232704296671488,-0.8145372938985567,-0.48158877982782056,0.9060329793006716,-0.5138808228281478,0.5566115286243463,-0.6120605797493264,1.9552468158064782,0.7345798472794599,0.6081511143176388,0.2349756872773074,0.6081511143176388,0.9776259405477873,0.9538838337472978,2.4267339760166293,-0.4176406731946431,0.504501785431343,-0.1398785959133766,-0.5791140239235776,3.3258692872450646,-0.20023841286057453,2.233303018813176,2.6938037281589335,1.341820214976906,0.5566115286243463,0.3716548214149085,-0.05073464252917762,1.0945486200442405,-1.0981562573910337,0.4782294385308354,-0.3232704296671488,-0.1699640181909275,-1.929913063783283,-0.23070398700916023,0.09425478550483424,-1.246298549886792,-0.2922176920491657,1.0247492400647817,-0.5463883460250468,-0.08026602431198727,1.4499668634992937,-0.7461118187735932,-0.6452307866220199,0.42524226721919817,-0.385979494061243,0.06560596082580177,0.3716548214149085,-0.23070398700916023,1.8390187702748255,1.8780952360684287,-0.6452307866220199,-0.1699640181909275,-0.48158877982782056,0.9060329793006716,-1.246298549886792,0.1791846335137533,-1.3220563573737758,-0.1099799759281711,-0.23070398700916023,3.3953101294729233,-0.08026602431198727,0.8333224319696179,-0.4176406731946431,0.4782294385308354,-1.3989812878170513,-0.449509590099947,-0.6786274687643568,-0.1099799759281711,0.036784554335826614,0.9776259405477873,0.5566115286243463,-0.1699640181909275,0.007788633325283703,0.12273293000494902,-0.4176406731946431,-0.35452356200396523,1.0247492400647817,0.7345798472794599,-0.6786274687643568,-1.6779093391999742,3.08101788485959,-0.4176406731946431,1.0481326767167887,0.1791846335137533,0.6844163633500198,-0.35452356200396523,-0.1699640181909275,0.7594615984524137,-0.5463883460250468,-0.7122535027473694,0.7594615984524137,0.06560596082580177,-0.385979494061243,3.2836590722958277,0.5306286544959777,0.6337106835947478,0.2071618461975449,0.3446320422674998,-0.08026602431198727,-1.0981562573910337,-0.021383766664227755,1.9168361544314048,-0.1699640181909275,1.407013911282315,-0.20023841286057453,-2.2865857970685295,-0.08026602431198727,-0.1398785959133766,2.4950321897803915,-0.9543108287183288,0.9776259405477873,0.1791846335137533,-0.385979494061243,-0.05073464252917762,0.45181010850325676,-0.23070398700916023,-0.8839284596697314,0.5306286544959777,-0.1699640181909275,-0.7122535027473694,0.3716548214149085,-0.4176406731946431,0.9060329793006716,0.3446320422674998,-0.2922176920491657,0.15104226553426064,-0.5463883460250468,-0.780205401999509,-0.3232704296671488,0.6337106835947478,-0.9189941109407576,0.9060329793006716,0.007788633325283703,-0.1699640181909275,-0.3232704296671488,0.5306286544959777,1.4925203872541544,-0.780205401999509,0.09425478550483424,0.2071618461975449
| 2,702
|
Viral messenger rna synthesis
| 15
| 32
| 2.124298
| 0.033645
|
P49792,Q8NFH4,P35658,O75694,Q9BVL2,P12270,Q8N1F7,Q9BTX1,P55735,P62875,Q99567,Q8WUM0,Q12769,P19388,Q7Z3B4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
288,226,3,599,504,293,541,542,738,366,639,777,495,530,685
|
1676,599,293,530,1181,1288,3,1235,1456,288,1546,738,905,2460,366,1606,495,914,685,541,226,1659,1385,777,779,1306,639,542,504,926,2078,1481
|
-0.2922176920491657,0.4782294385308354,1.0012473661035215,0.5566115286243463,0.036784554335826614,-0.021383766664227755,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,-0.20023841286057453,0.3446320422674998,0.2071618461975449,-1.0257109093739025,0.8333224319696179,-0.23070398700916023,0.6081511143176388,0.2071618461975449,0.39852436325326,0.5566115286243463,1.1860066448125965,-0.26136298554392196,-0.08026602431198727,0.31745440163525057,0.31745440163525057,-0.021383766664227755,0.45181010850325676,0.5566115286243463,0.6081511143176388,0.2071618461975449,-0.5463883460250468,-0.1398785959133766
| 2,702
|
Neoplasm of the respiratory system
| 9
| 11
| 2.117163
| 0.034246
|
Q15645,Q14790,Q01844,P43246,P02545,P31749,P52701,P04637,P30154
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
681,329,133,630,178,145,441,529,186
|
178,529,186,145,630,441,133,1462,329,681,782
|
1.341820214976906,0.5566115286243463,1.2978377151319078,1.5346812984581808,0.45181010850325676,0.7095652084505555,1.6178517102360863,-0.1398785959133766,0.9300199004069388,0.39852436325326,0.31745440163525057
| 2,702
|
Aplasia hypoplasia of the lungs
| 10
| 27
| 2.116722
| 0.034283
|
P25705,O75844,Q7Z4L5,O96028,Q16134,O75419,P02545,P98175,Q53EZ4,O96000
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
252,314,105,75,28,414,178,310,383,400
|
968,2128,414,314,1878,400,75,178,2302,1685,2052,252,2543,310,1899,457,2246,28,383,1338,1156,988,105,1561,639,1758,1723
|
0.15104226553426064,-0.6120605797493264,0.7345798472794599,0.9538838337472978,-0.4176406731946431,0.7594615984524137,2.233303018813176,1.341820214976906,-0.780205401999509,-0.2922176920491657,-0.5463883460250468,1.1175832808973218,-1.208847161551696,0.9776259405477873,-0.4176406731946431,0.6844163633500198,-0.7122535027473694,3.1979755531726313,0.8088316185366753,-0.05073464252917762,0.06560596082580177,0.15104226553426064,1.9168361544314048,-0.20023841286057453,0.45181010850325676,-0.3232704296671488,-0.2922176920491657
| 2,702
|
SLC superfamily of solute carriers
| 8
| 43
| 2.10802
| 0.035029
|
Q8IXU6,P41440,P53985,Q70HW3,Q9H2D1,O43772,Q6NT16,Q9BQT8
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
33,67,100,6,73,9,19,23
|
1219,9,2085,2331,1878,2332,1681,2372,1775,2693,2554,2397,67,100,2380,2461,2221,134,19,988,1906,6,33,300,1706,1206,1063,748,23,1346,1255,73,590,2632,2291,1574,1668,1396,855,2578,936,1400,1441
|
0.007788633325283703,4.1389954392444945,-0.5791140239235776,-0.8145372938985567,-0.4176406731946431,-0.8145372938985567,-0.2922176920491657,-0.8839284596697314,-0.35452356200396523,-3.959608434173559,-1.246298549886792,-0.9189941109407576,2.339853291567594,1.9552468158064782,-0.8839284596697314,-1.0257109093739025,-0.6786274687643568,1.6178517102360863,3.6493512824571805,0.15104226553426064,-0.4176406731946431,4.700030074598367,3.08101788485959,1.0012473661035215,-0.2922176920491657,0.036784554335826614,0.12273293000494902,0.3446320422674998,3.4500635955114625,-0.05073464252917762,0.007788633325283703,2.2691039308231553,0.504501785431343,-1.5564687430126587,-0.7461118187735932,-0.20023841286057453,-0.26136298554392196,-0.08026602431198727,0.26262791247117023,-1.2840336152236627,0.2071618461975449,-0.08026602431198727,-0.1099799759281711
| 2,702
|
Xerostomia
| 7
| 13
| 2.10137
| 0.035609
|
Q14739,P50995,Q15165,Q14203,P35637,P43243,Q92804
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
457,390,43,425,81,578,90
|
2131,1321,604,81,578,390,1938,811,425,457,43,90,999
|
-0.6120605797493264,-0.05073464252917762,0.4782294385308354,2.160827351832918,0.504501785431343,0.784211761763469,-0.449509590099947,0.29012025009768083,0.7345798472794599,0.6844163633500198,2.677578161237687,2.049862232695574,0.15104226553426064
| 2,702
|
Translation factors
| 9
| 36
| 2.08947
| 0.036665
|
P23588,O75153,Q13144,O00303,P55010,O75822,Q14240,Q15056,Q9NR50
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
259,5,354,192,11,324,370,406,384
|
192,1445,1221,2044,669,5,829,324,672,401,1587,2588,945,259,1592,1972,1361,2237,11,1239,1847,739,869,1293,1849,1329,1330,354,1850,1553,1901,370,406,724,384,1718
|
1.2756876781734239,-0.1398785959133766,0.007788633325283703,-0.5463883460250468,0.39852436325326,4.720152240851799,0.26262791247117023,0.9300199004069388,0.39852436325326,0.7594615984524137,-0.23070398700916023,-1.3603708589860188,0.1791846335137533,1.0945486200442405,-0.23070398700916023,-0.48158877982782056,-0.08026602431198727,-0.7122535027473694,4.069090601822336,0.007788633325283703,-0.385979494061243,0.3446320422674998,0.2349756872773074,-0.021383766664227755,-0.385979494061243,-0.05073464252917762,-0.05073464252917762,0.8576854474690445,-0.385979494061243,-0.20023841286057453,-0.4176406731946431,0.8333224319696179,0.7594615984524137,0.3716548214149085,0.8088316185366753,-0.2922176920491657
| 2,702
|
Underdeveloped supraorbital ridges
| 7
| 11
| 2.083729
| 0.037185
|
O75381,Q08J23,P52732,P98175,P50542,P40855,Q6PGP7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,424,421,310,365,337,684
|
99,1081,706,337,365,421,310,1241,424,988,684
|
1.9552468158064782,0.09425478550483424,0.3716548214149085,0.9060329793006716,0.8333224319696179,0.7345798472794599,0.9776259405477873,0.007788633325283703,0.7345798472794599,0.15104226553426064,0.39852436325326
| 2,702
|
Abnormality of the anterior fontanelle
| 11
| 30
| 2.067331
| 0.038703
|
O75381,Q9UQE7,Q16134,Q08J23,Q15813,O75419,P50542,O75718,Q32P28,Q9Y487,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,376,28,424,407,414,365,307,27,156,337
|
451,99,414,2657,307,2302,1081,1030,2052,1736,1036,2010,2543,1843,337,974,365,607,424,2407,1196,407,28,27,988,1340,1474,376,156,936
|
0.6844163633500198,1.9552468158064782,0.7345798472794599,-1.8870329360960985,0.9776259405477873,-0.780205401999509,0.09425478550483424,0.12273293000494902,-0.5463883460250468,-0.3232704296671488,0.12273293000494902,-0.5138808228281478,-1.208847161551696,-0.385979494061243,0.9060329793006716,0.15104226553426064,0.8333224319696179,0.4782294385308354,0.7345798472794599,-0.9189941109407576,0.036784554335826614,0.7594615984524137,3.1979755531726313,3.2836590722958277,0.15104226553426064,-0.05073464252917762,-0.1398785959133766,0.8333224319696179,1.4925203872541544,0.2071618461975449
| 2,702
|
Abnormality of pulmonary circulation
| 9
| 26
| 2.065194
| 0.038905
|
P25705,Q08AM6,O75844,P00403,Q14108,P31749,P02545,Q8IZA0,Q9NZ08
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
252,290,314,165,147,145,178,217,221
|
2657,314,1354,400,165,178,1229,1030,2052,1359,252,145,1325,1544,1891,978,290,147,1426,1156,988,217,1303,1474,2656,221
|
-1.8870329360960985,0.9538838337472978,-0.08026602431198727,0.7594615984524137,1.407013911282315,1.341820214976906,0.007788633325283703,0.12273293000494902,-0.5463883460250468,-0.08026602431198727,1.1175832808973218,1.5346812984581808,-0.05073464252917762,-0.20023841286057453,-0.4176406731946431,0.15104226553426064,1.0247492400647817,1.5346812984581808,-0.1099799759281711,0.06560596082580177,0.15104226553426064,1.208590985594112,-0.021383766664227755,-0.1398785959133766,-1.8445118508373655,1.208590985594112
| 2,702
|
Cytokine receptor binding
| 7
| 20
| 2.05998
| 0.0394
|
Q14790,Q9H2J4,P48681,P14174,P62942,Q9NZ08,P62993
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
329,333,233,56,154,221,317
|
827,1768,56,1835,2589,1325,233,1501,154,317,2067,329,1703,433,1663,333,1068,221,857,1485
|
0.26262791247117023,-0.35452356200396523,2.4094934860042883,-0.385979494061243,-1.3603708589860188,-0.05073464252917762,1.1633112587408174,-0.1699640181909275,1.4925203872541544,0.9538838337472978,-0.5463883460250468,0.9300199004069388,-0.2922176920491657,0.7345798472794599,-0.26136298554392196,0.9300199004069388,0.12273293000494902,1.208590985594112,0.26262791247117023,-0.1398785959133766
| 2,702
|
Posttranscriptional regulation of gene expression
| 59
| 197
| 2.055561
| 0.039825
|
P23588,Q13464,Q9Y2W1,Q9H814,Q92945,P55010,Q07666,P31749,Q15056,Q86VM9,Q13868,P04637,Q969T7,P22626,P51114,Q13217,P11940,Q5JVF3,Q13151,Q6Y7W6,Q567V2,Q7L576,Q01085,Q96MU7,P12270,Q08J23,Q71RC2,P08670,P17844,P98175,Q9NZN8,Q9NQT5,P98179,P07910,O75844,Q9P2K5,Q9HCE1,P51116,Q10713,P16989,P00374,P52272,O95453,P19338,P35637,P43243,Q9Y2R0,Q9BWF3,Q14444,Q13310,Q92804,Q13144,Q14103,O60506,Q14240,Q9BPZ3,P34896,P67809,Q9Y6M1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
259,521,396,394,265,11,270,145,406,539,279,529,158,159,289,291,401,163,536,299,38,430,297,560,293,424,556,49,417,310,449,59,60,315,314,593,199,196,582,72,202,454,573,575,81,578,215,212,471,470,90,354,237,111,370,113,243,121,385
|
1581,792,668,1403,1445,1221,1676,2044,2163,111,2002,669,796,314,573,202,1926,529,2627,672,702,1731,315,49,401,293,1587,1493,2303,72,417,575,2588,1931,159,704,259,2267,654,2134,2054,2097,145,243,1289,1595,81,706,1497,2594,1084,2237,974,606,1934,578,1738,2375,2544,1695,805,289,196,607,454,2062,11,1646,1239,1847,2310,1787,739,979,1420,1984,2460,1293,2275,2276,1894,1849,2379,121,1327,907,709,310,60,1088,297,1241,1329,873,1242,270,910,424,1508,582,980,2067,354,811,536,291,470,1194,521,279,237,370,471,982,984,406,1555,2281,813,985,1151,913,743,38,163,1745,1467,613,1558,990,299,1747,556,2189,2111,430,2314,2548,539,1203,1163,2365,2070,1562,1471,2113,2071,1472,90,1753,921,265,996,158,1662,1708,1164,1564,560,1519,958,999,113,1345,212,666,1254,1064,2676,723,2288,724,1390,1919,394,1007,1573,1816,199,59,2202,1393,449,593,2470,1718,2551,1719,1528,215,2122,396,1120,1121,2471,385,1020
|
-0.23070398700916023,0.29012025009768083,0.39852436325326,-0.1099799759281711,-0.1398785959133766,0.007788633325283703,-0.2922176920491657,-0.5463883460250468,-0.6452307866220199,1.8585992820751742,-0.5138808228281478,0.39852436325326,0.29012025009768083,0.9538838337472978,0.504501785431343,1.2534305210935053,-0.449509590099947,0.5566115286243463,-1.5564687430126587,0.39852436325326,0.3716548214149085,-0.3232704296671488,0.9538838337472978,2.511943158877311,0.7594615984524137,1.0012473661035215,-0.23070398700916023,-0.1699640181909275,-0.780205401999509,2.2691039308231553,0.7345798472794599,0.504501785431343,-1.3603708589860188,-0.449509590099947,1.4499668634992937,0.3716548214149085,1.0945486200442405,-0.7461118187735932,0.42524226721919817,-0.6120605797493264,-0.5463883460250468,-0.5791140239235776,1.5346812984581808,1.1405038133141903,-0.021383766664227755,-0.23070398700916023,2.160827351832918,0.3716548214149085,-0.1699640181909275,-1.3989812878170513,0.09425478550483424,-0.7122535027473694,0.15104226553426064,0.4782294385308354,-0.449509590099947,0.504501785431343,-0.3232704296671488,-0.8839284596697314,-1.208847161551696,-0.2922176920491657,0.29012025009768083,1.0247492400647817,1.2756876781734239,0.4782294385308354,0.6844163633500198,-0.5463883460250468,4.069090601822336,-0.26136298554392196,0.007788633325283703,-0.385979494061243,-0.780205401999509,-0.35452356200396523,0.3446320422674998,0.15104226553426064,-0.1099799759281711,-0.48158877982782056,-1.0257109093739025,-0.021383766664227755,-0.7461118187735932,-0.7461118187735932,-0.4176406731946431,-0.385979494061243,-0.8839284596697314,1.7197212915351867,-0.05073464252917762,0.2071618461975449,0.3716548214149085,0.9776259405477873,2.3921856631301304,0.09425478550483424,1.0012473661035215,0.007788633325283703,-0.05073464252917762,0.2349756872773074,0.007788633325283703,1.0713987752533087,0.2071618461975449,0.7345798472794599,-0.1699640181909275,0.504501785431343,0.15104226553426064,-0.5463883460250468,0.8576854474690445,0.29012025009768083,0.5566115286243463,1.0247492400647817,0.6591319741805618,0.036784554335826614,0.5824518687603596,1.0481326767167887,1.1633112587408174,0.8333224319696179,0.6591319741805618,0.15104226553426064,0.15104226553426064,0.7594615984524137,-0.20023841286057453,-0.7461118187735932,0.29012025009768083,0.15104226553426064,0.06560596082580177,0.2071618461975449,0.3446320422674998,2.7260759733711035,1.4285407486745718,-0.3232704296671488,-0.1398785959133766,0.4782294385308354,-0.20023841286057453,0.15104226553426064,1.0012473661035215,-0.3232704296671488,0.5306286544959777,-0.6452307866220199,-0.5791140239235776,0.7345798472794599,-0.780205401999509,-1.208847161551696,0.5566115286243463,0.036784554335826614,0.06560596082580177,-0.8491105936663824,-0.5463883460250468,-0.20023841286057453,-0.1398785959133766,-0.5791140239235776,-0.5463883460250468,-0.1398785959133766,2.049862232695574,-0.3232704296671488,0.2071618461975449,1.0945486200442405,0.15104226553426064,1.4712931239277853,-0.26136298554392196,-0.2922176920491657,0.06560596082580177,-0.20023841286057453,0.5306286544959777,-0.1699640181909275,0.1791846335137533,0.15104226553426064,1.8390187702748255,-0.05073464252917762,1.231065281813778,0.42524226721919817,0.007788633325283703,0.12273293000494902,-2.195059359857069,0.3716548214149085,-0.7461118187735932,0.3716548214149085,-0.08026602431198727,-0.4176406731946431,0.784211761763469,0.15104226553426064,-0.20023841286057453,-0.35452356200396523,1.2756876781734239,2.4094934860042883,-0.6452307866220199,-0.08026602431198727,0.7095652084505555,0.504501785431343,-1.0257109093739025,-0.2922176920491657,-1.208847161551696,-0.2922176920491657,-0.1699640181909275,1.231065281813778,-0.5791140239235776,0.784211761763469,0.09425478550483424,0.09425478550483424,-1.0257109093739025,0.8088316185366753,0.15104226553426064
| 2,702
|
Export of viral ribonucleoproteins from nucleus
| 13
| 28
| 2.054374
| 0.03994
|
P49792,Q8NFH4,P35658,O75694,Q9BVL2,P12270,Q8N1F7,Q9BTX1,P55735,Q99567,Q8WUM0,Q12769,Q7Z3B4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
288,226,3,599,504,293,541,542,738,639,777,495,685
|
1632,599,293,3,1235,1456,288,1546,738,905,2276,1606,495,914,685,541,226,1659,1385,777,779,1306,639,542,504,926,2078,1481
|
-0.26136298554392196,0.4782294385308354,1.0012473661035215,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,-0.20023841286057453,0.3446320422674998,0.2071618461975449,-0.7461118187735932,-0.23070398700916023,0.6081511143176388,0.2071618461975449,0.39852436325326,0.5566115286243463,1.1860066448125965,-0.26136298554392196,-0.08026602431198727,0.31745440163525057,0.31745440163525057,-0.021383766664227755,0.45181010850325676,0.5566115286243463,0.6081511143176388,0.2071618461975449,-0.5463883460250468,-0.1398785959133766
| 2,702
|
Negative regulation of response to external stimulus
| 7
| 37
| 2.04471
| 0.040883
|
P19474,P28070,P00813,Q6P1A2,Q9UMX5,Q96G23,P14174
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,10,42,76,77,142,56
|
1961,149,512,795,2657,2129,42,1229,2626,1492,56,1835,65,1838,10,2589,1412,1976,2178,1646,1502,262,1242,1372,2573,913,76,2191,1911,995,142,484,1108,1253,1717,77,486
|
-0.48158877982782056,1.5136495000737895,0.5824518687603596,0.29012025009768083,-1.8870329360960985,-0.6120605797493264,2.6938037281589335,0.007788633325283703,-1.5564687430126587,-0.1699640181909275,2.4094934860042883,-0.385979494061243,2.3573660616958487,-0.385979494061243,4.127425604581578,-1.3603708589860188,-0.1099799759281711,-0.48158877982782056,-0.6452307866220199,-0.26136298554392196,-0.1699640181909275,1.0945486200442405,0.007788633325283703,-0.08026602431198727,-1.2840336152236627,0.2071618461975449,2.215294149477837,-0.6452307866220199,-0.4176406731946431,0.15104226553426064,1.5556166081262797,0.6337106835947478,0.09425478550483424,0.007788633325283703,-0.2922176920491657,2.215294149477837,0.6337106835947478
| 2,702
|
Abnormal epidermal morphology
| 8
| 16
| 2.037265
| 0.041623
|
O75844,Q14574,P15924,Q06136,P02545,P31749,P52732,P14923
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
314,104,326,367,178,145,421,402
|
2262,314,1772,178,402,326,1451,1411,145,580,421,2183,367,104,1906,486
|
-0.7461118187735932,0.9538838337472978,-0.35452356200396523,1.341820214976906,0.7594615984524137,0.9300199004069388,-0.1398785959133766,-0.1099799759281711,1.5346812984581808,0.504501785431343,0.7345798472794599,-0.6452307866220199,0.8333224319696179,1.9168361544314048,-0.4176406731946431,0.6337106835947478
| 2,702
|
Rhobtb gtpase cycle
| 14
| 28
| 2.033782
| 0.041974
|
P07910,Q13464,P78371,P38159,Q12792,P62995,P61201,P08670,Q13098,Q5VTR2,Q9NYL9,Q8N684,Q8WWQ0,Q9BT78
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
315,521,518,91,710,235,608,49,368,211,448,746,717,749
|
1404,1129,315,1077,49,1178,91,1597,608,235,518,710,368,521,1552,2143,743,1428,211,842,2533,746,717,2196,1252,749,448,1482
|
-0.1099799759281711,0.06560596082580177,0.9538838337472978,0.09425478550483424,2.511943158877311,0.036784554335826614,2.031097928717653,-0.23070398700916023,0.4782294385308354,1.1633112587408174,0.5824518687603596,0.3716548214149085,0.8333224319696179,0.5824518687603596,-0.20023841286057453,-0.6120605797493264,0.3446320422674998,-0.1099799759281711,1.231065281813778,0.26262791247117023,-1.1716755310485276,0.3446320422674998,0.3716548214149085,-0.6452307866220199,0.007788633325283703,0.3446320422674998,0.7095652084505555,-0.1398785959133766
| 2,702
|
Regulation of mrna stability by proteins that bind au rich elements
| 17
| 59
| 2.02903
| 0.042455
|
P35658,P49721,Q5RKV6,Q92945,P28070,Q01105,Q9NQT5,Q14103,Q99436,P60900,P20618,P31749,P39687,P28074,O00233,Q13868,P28072
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
3,68,330,265,10,169,59,237,143,391,231,145,209,58,276,279,253
|
488,2261,276,1673,1402,1632,897,649,573,2627,1231,401,801,231,1838,1182,629,1134,1887,10,253,58,145,657,3,1779,209,1783,1644,1890,68,2403,391,534,906,1421,1941,836,169,1329,873,1191,1090,279,237,2583,2020,984,1151,913,330,265,616,143,1951,59,1958,1577,1528
|
0.6081511143176388,-0.7461118187735932,1.0481326767167887,-0.2922176920491657,-0.1099799759281711,-0.26136298554392196,0.2071618461975449,0.42524226721919817,0.504501785431343,-1.5564687430126587,0.007788633325283703,0.7594615984524137,0.29012025009768083,1.1633112587408174,-0.385979494061243,0.036784554335826614,0.45181010850325676,0.06560596082580177,-0.4176406731946431,4.127425604581578,1.1175832808973218,2.4094934860042883,1.5346812984581808,0.42524226721919817,4.779930332154013,-0.35452356200396523,1.231065281813778,-0.35452356200396523,-0.26136298554392196,-0.4176406731946431,2.339853291567594,-0.9189941109407576,0.784211761763469,0.5566115286243463,0.2071618461975449,-0.1099799759281711,-0.449509590099947,0.26262791247117023,1.3853854720918395,-0.05073464252917762,0.2349756872773074,0.036784554335826614,0.09425478550483424,1.0481326767167887,1.1633112587408174,-1.3220563573737758,-0.5138808228281478,0.15104226553426064,0.06560596082580177,0.2071618461975449,0.9300199004069388,1.0945486200442405,0.4782294385308354,1.5556166081262797,-0.449509590099947,2.4094934860042883,-0.449509590099947,-0.20023841286057453,-0.1699640181909275
| 2,702
|
Steroid binding
| 7
| 20
| 2.027943
| 0.042566
|
O15173,P45880,Q9H4L5,P21796,P38435,Q14108,O15118
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
286,195,107,232,109,147,306
|
569,306,286,323,970,1229,1682,1281,232,675,1640,1033,109,195,2638,147,959,2152,2539,107
|
0.504501785431343,0.9776259405477873,1.0247492400647817,0.9300199004069388,0.15104226553426064,0.007788633325283703,-0.2922176920491657,-0.021383766664227755,1.1633112587408174,0.39852436325326,-0.26136298554392196,0.12273293000494902,1.8780952360684287,1.2756876781734239,-1.6779093391999742,1.5346812984581808,0.1791846335137533,-0.6120605797493264,-1.1716755310485276,1.8975073051504956
| 2,702
|
Limb ataxia
| 10
| 22
| 2.016562
| 0.043741
|
O14773,P41440,Q9Y4W6,Q10713,Q8IV08,Q9NR77,Q14108,O15020,P07196,Q9BUK6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
624,67,597,582,174,344,147,347,185,126
|
2161,2083,624,347,1229,1730,185,1774,1587,2305,1413,67,582,1243,147,174,999,126,344,692,1439,597
|
-0.6452307866220199,-0.5791140239235776,0.45181010850325676,0.8819218929788717,0.007788633325283703,-0.3232704296671488,1.2978377151319078,-0.35452356200396523,-0.23070398700916023,-0.780205401999509,-0.1099799759281711,2.339853291567594,0.504501785431343,0.007788633325283703,1.5346812984581808,1.363654540627114,0.15104226553426064,1.6995293541371095,0.9060329793006716,0.39852436325326,-0.1099799759281711,0.504501785431343
| 2,702
|
Ns1 mediated effects on host pathways
| 16
| 33
| 2.01176
| 0.044245
|
P49792,Q8NFH4,P35658,Q86U42,O75694,P52292,P12270,Q8N1F7,Q9BTX1,Q9BVL2,P52294,P55735,Q99567,Q8WUM0,Q12769,Q7Z3B4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
288,226,3,254,599,296,293,541,542,504,735,738,639,777,495,685
|
1674,1582,599,293,2588,3,1235,1456,288,296,735,1546,738,905,1606,495,1149,914,685,254,541,226,1659,1385,777,779,1306,639,542,504,926,2078,1481
|
-0.2922176920491657,-0.23070398700916023,0.4782294385308354,1.0012473661035215,-1.3603708589860188,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,1.0012473661035215,0.3446320422674998,-0.20023841286057453,0.3446320422674998,0.2071618461975449,-0.23070398700916023,0.6081511143176388,0.06560596082580177,0.2071618461975449,0.39852436325326,1.1175832808973218,0.5566115286243463,1.1860066448125965,-0.26136298554392196,-0.08026602431198727,0.31745440163525057,0.31745440163525057,-0.021383766664227755,0.45181010850325676,0.5566115286243463,0.6081511143176388,0.2071618461975449,-0.5463883460250468,-0.1398785959133766
| 2,702
|
Nuclear import of rev protein
| 14
| 30
| 2.011706
| 0.044251
|
P49792,Q8NFH4,P35658,P06748,O75694,Q9BVL2,P12270,Q8N1F7,Q9BTX1,P55735,Q99567,Q8WUM0,Q12769,Q7Z3B4
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
288,226,3,702,599,504,293,541,542,738,639,777,495,685
|
599,702,293,2168,3,1235,1456,288,1546,738,905,2276,1606,495,1149,914,685,541,226,1659,1385,777,779,1306,639,542,504,926,2078,1481
|
0.4782294385308354,0.3716548214149085,1.0012473661035215,-0.6452307866220199,4.779930332154013,0.007788633325283703,-0.1398785959133766,1.0247492400647817,-0.20023841286057453,0.3446320422674998,0.2071618461975449,-0.7461118187735932,-0.23070398700916023,0.6081511143176388,0.06560596082580177,0.2071618461975449,0.39852436325326,0.5566115286243463,1.1860066448125965,-0.26136298554392196,-0.08026602431198727,0.31745440163525057,0.31745440163525057,-0.021383766664227755,0.45181010850325676,0.5566115286243463,0.6081511143176388,0.2071618461975449,-0.5463883460250468,-0.1398785959133766
| 2,702
|
External side of plasma membrane
| 6
| 20
| 2.011539
| 0.044269
|
P41440,P08183,P42892,P00813,Q4VCS5,O15439
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
67,70,194,42,245,277
|
277,1227,308,466,42,2356,831,1773,1320,70,2334,1929,2054,67,194,1544,1740,2546,245,590
|
1.0481326767167887,0.007788633325283703,0.9776259405477873,0.6591319741805618,2.6938037281589335,-0.8491105936663824,0.26262791247117023,-0.35452356200396523,-0.05073464252917762,2.2868970423085044,-0.8145372938985567,-0.449509590099947,-0.5463883460250468,2.339853291567594,1.2756876781734239,-0.20023841286057453,-0.3232704296671488,-1.208847161551696,1.1405038133141903,0.504501785431343
| 2,702
|
Negative regulation of rna splicing
| 7
| 17
| 2.01075
| 0.044352
|
P22626,Q13242,P98175,O75494,P61978,P38159,Q16629
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
159,263,310,182,153,91,428
|
2230,182,159,1183,1453,91,153,1893,310,1242,909,1988,263,520,1945,428,1999
|
-0.7122535027473694,1.319881581600934,1.4499668634992937,0.036784554335826614,-0.1398785959133766,2.031097928717653,1.4925203872541544,-0.4176406731946431,0.9776259405477873,0.007788633325283703,0.2071618461975449,-0.48158877982782056,1.0945486200442405,0.5824518687603596,-0.449509590099947,0.7345798472794599,-0.48158877982782056
| 2,702
|
Dysdiadochokinesis
| 7
| 14
| 2.003347
| 0.04514
|
P41440,Q9Y4W6,O75027,P20700,Q6DKK2,O15020,Q9BUK6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
67,597,572,418,53,347,126
|
347,572,2440,832,418,1413,67,1184,1237,53,999,126,692,597
|
0.8819218929788717,0.504501785431343,-0.9898819580382101,0.26262791247117023,0.7345798472794599,-0.1099799759281711,2.339853291567594,0.036784554335826614,0.007788633325283703,2.4439076160408386,0.15104226553426064,1.6995293541371095,0.39852436325326,0.504501785431343
| 2,702
|
Fatigable weakness of bulbar muscles
| 7
| 14
| 1.994858
| 0.046058
|
P50995,Q15165,Q14203,P06753,P35637,P43243,Q92804
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
390,43,425,229,81,578,90
|
2131,229,1321,604,81,578,390,1938,811,425,43,90,999,2041
|
-0.6120605797493264,1.1633112587408174,-0.05073464252917762,0.4782294385308354,2.160827351832918,0.504501785431343,0.784211761763469,-0.449509590099947,0.29012025009768083,0.7345798472794599,2.677578161237687,2.049862232695574,0.15104226553426064,-0.5138808228281478
| 2,702
|
Cleavage furrow
| 6
| 18
| 1.98884
| 0.046719
|
P35579,O75935,Q14141,O14578,Q9H0H5,P35580
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
316,325,141,171,115,309
|
171,325,1354,671,1773,1080,1035,316,309,1542,141,1150,1051,2145,383,115,1116,2609
|
1.363654540627114,0.9300199004069388,-0.08026602431198727,0.39852436325326,-0.35452356200396523,0.09425478550483424,0.12273293000494902,0.9538838337472978,0.9776259405477873,-0.20023841286057453,1.5556166081262797,0.06560596082580177,0.12273293000494902,-0.6120605797493264,0.8088316185366753,1.819353019865366,0.09425478550483424,-1.4378918990793144
| 2,702
|
Abnormality of the achilles tendon
| 9
| 12
| 1.98285
| 0.047384
|
Q13642,Q8N2K0,Q92734,P50402,O60313,Q08J23,Q15149,Q8TD16,P02545
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
609,264,301,295,571,424,371,343,178
|
571,178,295,424,609,371,264,343,686,301,2199,1763
|
0.504501785431343,1.341820214976906,1.0012473661035215,0.7345798472794599,0.4782294385308354,0.8333224319696179,1.0945486200442405,0.9060329793006716,0.39852436325326,1.0012473661035215,-0.6452307866220199,-0.3232704296671488
| 2,702
|
Abnormal delivery
| 7
| 18
| 1.979283
| 0.047784
|
O75844,Q01082,O14802,P06753,P02545,O75718,Q9Y487
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
314,535,451,229,178,307,156
|
451,571,307,314,1772,178,229,1685,803,1364,977,535,1791,1381,1164,1758,156,936
|
0.6844163633500198,0.504501785431343,0.9776259405477873,0.9538838337472978,-0.35452356200396523,1.341820214976906,1.1633112587408174,-0.2922176920491657,0.29012025009768083,-0.08026602431198727,0.15104226553426064,0.5566115286243463,-0.35452356200396523,-0.08026602431198727,0.06560596082580177,-0.3232704296671488,1.4925203872541544,0.2071618461975449
| 2,702
|
Fatigable weakness of respiratory muscles
| 6
| 13
| 1.975567
| 0.048204
|
P50995,Q15165,Q14203,P35637,P43243,Q92804
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
390,43,425,81,578,90
|
2131,1321,604,81,578,390,1938,811,425,43,90,999,1527
|
-0.6120605797493264,-0.05073464252917762,0.4782294385308354,2.160827351832918,0.504501785431343,0.784211761763469,-0.449509590099947,0.29012025009768083,0.7345798472794599,2.677578161237687,2.049862232695574,0.15104226553426064,-0.1699640181909275
| 2,702
|
Dna modification
| 7
| 26
| 1.961804
| 0.049785
|
O75844,Q9Y2W6,Q5RKV6,P09874,Q8NB78,Q9NQT5,Q03164
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
314,201,330,14,342,59,62
|
793,314,2209,2004,14,1777,2134,1593,948,2376,1240,62,1462,1152,330,392,1382,844,342,1387,1061,2288,59,1715,2643,201
|
0.29012025009768083,0.9538838337472978,-0.6786274687643568,-0.5138808228281478,3.9740289947398435,-0.35452356200396523,-0.6120605797493264,-0.23070398700916023,0.1791846335137533,-0.8839284596697314,0.007788633325283703,2.374810019413564,-0.1398785959133766,0.06560596082580177,0.9300199004069388,0.784211761763469,-0.08026602431198727,0.26262791247117023,0.9060329793006716,-0.08026602431198727,0.12273293000494902,-0.7461118187735932,2.4094934860042883,-0.2922176920491657,-1.6779093391999742,1.2756876781734239
| 2,702
|
Vacuole
| 61
| 187
| 4.600285
| 0.000004
|
P42785,P16278,O00560,P19474,Q8IV08,Q8NCC3,Q9BTU6,Q15165,Q9NX40,P20645,P61916,Q8TCT8,Q8NB49,Q14108,Q8NHP8,Q92820,O15118,P06280,Q5BJF2,P61421,P38435,P10619,P06865,Q9UIQ6,P15586,P50897,P09496,P07602,O15260,Q07065,P53680,Q8WTV0,P17900,P04062,O60749,O14773,Q9Y487,Q9HD26,P42892,Q01085,P11117,Q9H7Z7,Q13217,P00813,Q9UHG3,P54802,Q99538,Q9BTY2,Q9NRR5,O00584,O95721,P07437,P38571,P51790,Q13510,P11279,P41440,Q8WWQ0,Q9Y5K8,P68371,P55735
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,128,130,131,4,134,264,262,404,268,142,144,146,19,147,282,24,149,28,414,413,163,168,45,174,52,424,57,59,320,318,69,70,443,442,201,78,470,80,331,83,350,348,93,95,98,99,230,362,103,104,105,233,368,111,236,115,119,388,124,380
|
1925,1812,130,103,2475,2522,201,1411,24,59,1357,1976,815,926,1978,579,442,1496,2144,2185,762,965,1555,104,1711,2586,93,443,582,1875,149,168,560,2189,105,57,1096,1768,820,969,701,1416,732,424,620,463,163,83,892,1049,236,174,128,70,131,268,823,1772,2415,2565,671,2191,1877,897,1673,898,413,233,1780,1179,115,1612,0,1569,80,1613,2264,2394,1989,1057,52,2197,738,1831,1422,1724,368,2042,2297,318,938,98,1882,380,674,2546,1280,1425,2655,414,142,1726,124,1181,1994,331,1107,1730,2399,1787,320,482,594,1514,679,1284,348,111,864,19,1947,262,28,1999,4,806,146,750,134,637,147,144,69,1122,119,548,282,529,752,1395,1852,875,956,2348,1076,99,2492,550,2210,530,264,230,782,878,1344,2060,1038,2379,1751,1915,350,1806,2109,470,362,404,1541,2583,880,1252,1296,2217,1595,2316,95,1348,45,1704,2022,1004,1706,554,2071,2072,78,388,1548
|
-0.43976167580769304,-0.37984219227896826,1.6176488501837785,1.8395473434978173,-0.9440776667177786,-1.0439690553345753,1.255425828169697,-0.14649000038336524,3.530739879481159,2.419034532533944,-0.1180065861783075,-0.4699677127277454,0.23937792178355133,0.15895673427969537,-0.4699677127277454,0.4481994586006217,0.6245521818790327,-0.2039047156366997,-0.5924746168808616,-0.6235310490678561,0.2923398612170866,0.13188385952514886,-0.2328390217993925,1.8395473434978173,-0.32056824010222307,-1.2492972789568666,1.9760700997311131,0.6245521818790327,0.4481994586006217,-0.4097204049195783,1.4925940643576996,1.4075642865122227,0.473746678395286,-0.6235310490678561,1.8395473434978173,2.436706104734128,0.0498499651371408,-0.350125356105606,0.23937792178355133,0.13188385952514886,0.3447912610633156,-0.14649000038336524,0.31862879037972053,0.6492831048866388,0.4225314103597223,0.5997077106006617,1.4289490678170462,2.1465741639128653,0.18589586847145548,0.07733177575208161,1.0988376535312658,1.386093528320324,1.638208714171853,2.2572569188414064,1.5970092420957023,1.0072634916981495,0.23937792178355133,-0.350125356105606,-0.8459514851409792,-1.1456872992127736,0.37082842982646413,-0.6235310490678561,-0.4097204049195783,0.18589586847145548,-0.2911692129463672,0.18589586847145548,0.673901466516914,1.1214892721063172,-0.350125356105606,-0.005531837066441173,1.7398321727024608,-0.2619266677946719,6.217718739388483,-0.2328390217993925,2.202206192643275,-0.2619266677946719,-0.6861725882485472,-0.8136248100970255,-0.4699677127277454,0.07733177575208161,2.678047917700652,-0.6235310490678561,0.31862879037972053,-0.37984219227896826,-0.14649000038336524,-0.32056824010222307,0.747090864182487,-0.5003402500028168,-0.7177615370892623,0.8431585826801586,0.15895673427969537,1.8789142803170127,-0.4097204049195783,0.7228043903765459,0.37082842982646413,-1.0776690173461208,-0.06148029559266701,-0.14649000038336524,-1.7599354012543078,0.673901466516914,1.5554884161976426,-0.32056824010222307,1.6586894203500797,-0.005531837066441173,-0.4699677127277454,0.8193015508006276,0.0498499651371408,-0.32056824010222307,-0.8136248100970255,-0.350125356105606,0.8431585826801586,0.5747486913303033,0.4481994586006217,-0.2039047156366997,0.37082842982646413,-0.06148029559266701,0.7953385242734627,1.7799433878907398,0.2127025180887077,4.111237733873485,-0.43976167580769304,1.0303037635203478,3.3710652583540575,-0.4699677127277454,5.2288928568634425,0.2659233011870234,1.5136414157872253,0.31862879037972053,1.5970092420957023,0.4225314103597223,1.5136414157872253,1.5346059932631821,2.275479978158442,0.0498499651371408,1.7196623603455143,0.49917415125399284,0.9608846498386505,0.5244829444562599,0.31862879037972053,-0.1180065861783075,-0.37984219227896826,0.2127025180887077,0.15895673427969537,-0.7495318851344548,0.07733177575208161,1.8789142803170127,-0.9440776667177786,0.49917415125399284,-0.6235310490678561,0.5244829444562599,1.0303037635203478,1.1440456767678313,0.2923398612170866,0.2127025180887077,-0.08967050071108885,-0.5003402500028168,0.10467597056101892,-0.7814856320202566,-0.32056824010222307,-0.4097204049195783,0.7953385242734627,-0.350125356105606,-0.5308810490428666,0.5997077106006617,0.7712686001756313,0.698408241052304,-0.2039047156366997,-1.2145462814230732,0.2127025180887077,-0.03343454335768025,-0.06148029559266701,-0.6235310490678561,-0.2328390217993925,-0.7177615370892623,1.9567810941536743,-0.08967050071108885,2.827512784417395,-0.2911692129463672,-0.4699677127277454,0.13188385952514886,-0.2911692129463672,0.49917415125399284,-0.5003402500028168,-0.5003402500028168,2.2206204495029636,0.7228043903765459,-0.2039047156366997
| 2,702
|
Transporter activity
| 51
| 161
| 4.327809
| 0.000015
|
Q99595,Q9NS69,Q6NT16,O75964,Q9P0J0,O43772,O15439,Q93050,Q8IXU6,P61916,Q8NB49,P45880,O15118,P21796,P61421,P38435,P30536,P00403,Q9C0H2,P06576,Q13423,Q70HW3,O96000,Q9H2D1,Q6N075,Q9Y277,O15173,P08183,P53985,Q8WTV0,P17900,P04062,Q9Y487,L0R6Q1,Q6P4A7,Q9H2H9,Q15388,P56385,Q8NBU5,Q9H4L5,Q9UBX3,P13073,P51790,O95139,P56134,P41440,Q96NB2,Q9Y5K8,Q9HD20,Q7KZN9,O43676
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
5,6,7,256,532,10,267,529,12,142,146,23,24,31,414,413,412,35,165,292,177,49,172,184,58,329,187,189,192,69,70,443,78,440,75,84,86,347,488,100,516,477,368,474,369,115,511,388,252,504,127
|
440,2142,1867,614,1708,852,24,187,267,127,925,926,10,1131,888,1361,730,646,889,1136,256,966,474,856,1415,1499,818,1931,2658,172,699,35,443,764,968,1462,1048,292,560,820,189,969,666,1268,2669,1980,1098,477,702,70,1771,1503,649,823,1772,31,669,1417,621,896,1463,1272,412,2364,2688,1015,898,413,1780,115,23,1370,2193,1421,2394,2331,368,2042,1017,566,1227,192,369,347,414,1680,142,2127,1786,1107,1471,1283,177,707,1062,86,1686,544,1998,1288,58,7,713,2053,75,49,504,12,836,146,488,948,2235,1030,528,1586,69,2467,529,2665,1956,511,1440,639,1643,1034,5,780,640,2210,781,1648,1342,2104,165,1038,184,84,1915,100,1294,608,252,6,532,516,721,611,1348,812,2176,1759,329,1215,78,884,388,1084,2616,789,1971
|
0.6245521818790327,-0.5924746168808616,-0.4097204049195783,0.4225314103597223,-0.32056824010222307,0.2127025180887077,3.530739879481159,1.3428914236840213,1.0072634916981495,1.638208714171853,0.15895673427969537,0.15895673427969537,4.396604319498196,0.02222921008355008,0.18589586847145548,-0.1180065861783075,0.31862879037972053,0.39674143767950243,0.18589586847145548,0.02222921008355008,1.0303037635203478,0.13188385952514886,0.5747486913303033,0.2127025180887077,-0.14649000038336524,-0.2039047156366997,0.23937792178355133,-0.43976167580769304,-1.8368287909913394,1.386093528320324,0.3447912610633156,3.1141580717849924,0.6245521818790327,0.2923398612170866,0.13188385952514886,-0.17512221304650355,0.07733177575208161,0.9141025725456303,0.473746678395286,0.23937792178355133,1.3428914236840213,0.13188385952514886,0.37082842982646413,-0.06148029559266701,-2.0740082524478405,-0.4699677127277454,0.0498499651371408,0.5747486913303033,0.3447912610633156,2.2572569188414064,-0.350125356105606,-0.2039047156366997,0.39674143767950243,0.23937792178355133,-0.350125356105606,3.281841750088034,0.37082842982646413,-0.14649000038336524,0.4225314103597223,0.18589586847145548,-0.17512221304650355,-0.06148029559266701,0.673901466516914,-0.7814856320202566,-3.1850832781614544,0.10467597056101892,0.18589586847145548,0.673901466516914,-0.350125356105606,1.7398321727024608,3.587597806701549,-0.1180065861783075,-0.6235310490678561,-0.14649000038336524,-0.8136248100970255,-0.7495318851344548,0.747090864182487,-0.5003402500028168,0.10467597056101892,0.473746678395286,-0.03343454335768025,1.3211587294181275,0.747090864182487,0.7953385242734627,0.673901466516914,-0.2911692129463672,1.5554884161976426,-0.5615918989070766,-0.350125356105606,0.0498499651371408,-0.17512221304650355,-0.06148029559266701,1.386093528320324,0.3447912610633156,0.07733177575208161,2.0714733698385936,-0.2911692129463672,0.49917415125399284,-0.4699677127277454,-0.06148029559266701,2.436706104734128,4.50404309487471,0.3447912610633156,-0.5003402500028168,2.2206204495029636,2.745005746127423,0.5496741112974982,4.224818104379722,0.23937792178355133,1.5136414157872253,0.5747486913303033,0.15895673427969537,-0.654763070997487,0.10467597056101892,0.5244829444562599,-0.2328390217993925,2.275479978158442,-0.9111757607706441,0.5244829444562599,-1.9147862223575949,-0.43976167580769304,0.5496741112974982,-0.14649000038336524,0.4225314103597223,-0.2619266677946719,0.10467597056101892,5.198120334434664,0.2923398612170866,0.4225314103597223,-0.6235310490678561,0.2923398612170866,-0.2619266677946719,-0.08967050071108885,-0.5308810490428666,1.4289490678170462,0.10467597056101892,1.3645361307346424,2.090348997439926,-0.4097204049195783,1.8789142803170127,-0.06148029559266701,0.4481994586006217,1.0532456836169948,4.890473754334426,0.5244829444562599,0.5496741112974982,0.3447912610633156,0.4481994586006217,-0.08967050071108885,0.2659233011870234,-0.5924746168808616,-0.32056824010222307,0.8431585826801586,-0.005531837066441173,2.2206204495029636,0.2127025180887077,0.7228043903765459,0.07733177575208161,-1.3548673355819485,0.2923398612170866,-0.43976167580769304
| 2,702
|
Lysosomal lumen
| 18
| 32
| 4.126366
| 0.000037
|
P16278,P54802,P10619,Q8IV08,Q99538,P17900,O00584,P06865,O14773,P61916,Q13510,P15586,Q8NHP8,Q14108,P50897,P11117,P06280,P07602
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,98,163,4,99,70,103,168,201,142,111,174,147,19,52,83,149,57
|
103,2475,201,926,443,582,149,168,57,1096,1768,701,463,163,83,892,174,128,70,413,233,52,98,142,111,19,4,750,147,99,782,880
|
1.8395473434978173,-0.9440776667177786,1.255425828169697,0.15895673427969537,0.6245521818790327,0.4481994586006217,1.4925940643576996,1.4075642865122227,2.436706104734128,0.0498499651371408,-0.350125356105606,0.3447912610633156,0.5997077106006617,1.4289490678170462,2.1465741639128653,0.18589586847145548,1.386093528320324,1.638208714171853,2.2572569188414064,0.673901466516914,1.1214892721063172,2.678047917700652,1.8789142803170127,1.5554884161976426,1.7799433878907398,4.111237733873485,5.2288928568634425,0.31862879037972053,1.5136414157872253,1.8789142803170127,0.2923398612170866,0.2127025180887077
| 2,702
|
Vacuolar lumen
| 22
| 60
| 3.801625
| 0.000144
|
P16278,O00560,Q8IV08,P61916,Q14108,Q8NHP8,P06280,P10619,P06865,P15586,P50897,P07602,P17900,O14773,P11117,P54802,Q99538,Q9BTY2,O00584,P07437,Q13510,P68371
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,130,4,142,19,147,149,163,168,174,52,57,70,201,83,98,99,230,103,105,111,124
|
130,103,2475,201,926,2586,443,582,149,168,560,105,57,1096,1768,701,463,163,83,892,1049,174,128,70,2191,1877,413,233,1989,52,2197,2297,938,98,1882,2655,142,124,1181,1107,1730,348,111,19,1947,4,750,147,282,1395,2348,1076,99,530,230,782,350,2583,880,1706
|
1.6176488501837785,1.8395473434978173,-0.9440776667177786,1.255425828169697,0.15895673427969537,-1.2492972789568666,0.6245521818790327,0.4481994586006217,1.4925940643576996,1.4075642865122227,0.473746678395286,1.8395473434978173,2.436706104734128,0.0498499651371408,-0.350125356105606,0.3447912610633156,0.5997077106006617,1.4289490678170462,2.1465741639128653,0.18589586847145548,0.07733177575208161,1.386093528320324,1.638208714171853,2.2572569188414064,-0.6235310490678561,-0.4097204049195783,0.673901466516914,1.1214892721063172,-0.4699677127277454,2.678047917700652,-0.6235310490678561,-0.7177615370892623,0.15895673427969537,1.8789142803170127,-0.4097204049195783,-1.7599354012543078,1.5554884161976426,1.6586894203500797,-0.005531837066441173,0.0498499651371408,-0.32056824010222307,0.7953385242734627,1.7799433878907398,4.111237733873485,-0.43976167580769304,5.2288928568634425,0.31862879037972053,1.5136414157872253,0.9608846498386505,-0.1180065861783075,-0.7495318851344548,0.07733177575208161,1.8789142803170127,0.5244829444562599,1.1440456767678313,0.2923398612170866,0.7953385242734627,-1.2145462814230732,0.2127025180887077,-0.2911692129463672
| 2,702
|
Vacuolar membrane
| 34
| 105
| 3.675074
| 0.000238
|
P42785,Q9BTU6,Q8IV08,P20645,Q93050,Q8TCT8,Q8NB49,Q14108,Q9Y2T2,O15118,Q99747,P61421,P10619,Q9UIQ6,P09496,P07602,O15260,Q07065,P53680,Q8WTV0,P04062,Q9Y487,Q9HD26,P42892,P11117,P10253,O95721,P51790,Q08AM6,P11279,P41440,Q8WWQ0,Q9Y5K8,P55735
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,264,4,268,529,144,146,19,554,24,550,414,163,45,424,57,59,320,318,69,443,78,470,80,83,463,104,368,482,236,115,119,388,380
|
1812,2522,24,59,1357,815,1978,579,1496,2144,762,965,1555,104,1711,443,1875,560,57,820,969,1416,732,424,463,163,83,892,236,268,823,1772,2415,897,1673,898,1780,1179,115,1612,0,80,2264,2394,1831,1422,368,2042,318,380,674,1280,1425,414,1726,1994,1787,320,482,594,1514,19,1999,4,806,146,637,144,69,1122,119,548,529,1852,875,956,550,2210,264,878,1344,2060,1038,2379,1751,1915,1806,2109,470,1541,880,1252,1296,2217,2316,1348,45,1704,2022,1004,554,2071,2072,78,388
|
-0.37984219227896826,-1.0439690553345753,3.530739879481159,2.419034532533944,-0.1180065861783075,0.23937792178355133,-0.4699677127277454,0.4481994586006217,-0.2039047156366997,-0.5924746168808616,0.2923398612170866,0.13188385952514886,-0.2328390217993925,1.8395473434978173,-0.32056824010222307,0.6245521818790327,-0.4097204049195783,0.473746678395286,2.436706104734128,0.23937792178355133,0.13188385952514886,-0.14649000038336524,0.31862879037972053,0.6492831048866388,0.5997077106006617,1.4289490678170462,2.1465741639128653,0.18589586847145548,1.0988376535312658,1.0072634916981495,0.23937792178355133,-0.350125356105606,-0.8459514851409792,0.18589586847145548,-0.2911692129463672,0.18589586847145548,-0.350125356105606,-0.005531837066441173,1.7398321727024608,-0.2619266677946719,6.217718739388483,2.202206192643275,-0.6861725882485472,-0.8136248100970255,-0.37984219227896826,-0.14649000038336524,0.747090864182487,-0.5003402500028168,0.8431585826801586,0.7228043903765459,0.37082842982646413,-0.06148029559266701,-0.14649000038336524,0.673901466516914,-0.32056824010222307,-0.4699677127277454,-0.350125356105606,0.8431585826801586,0.5747486913303033,0.4481994586006217,-0.2039047156366997,4.111237733873485,-0.4699677127277454,5.2288928568634425,0.2659233011870234,1.5136414157872253,0.4225314103597223,1.5346059932631821,2.275479978158442,0.0498499651371408,1.7196623603455143,0.49917415125399284,0.5244829444562599,-0.37984219227896826,0.2127025180887077,0.15895673427969537,0.49917415125399284,-0.6235310490678561,1.0303037635203478,0.2127025180887077,-0.08967050071108885,-0.5003402500028168,0.10467597056101892,-0.7814856320202566,-0.32056824010222307,-0.4097204049195783,-0.350125356105606,-0.5308810490428666,0.5997077106006617,-0.2039047156366997,0.2127025180887077,-0.03343454335768025,-0.06148029559266701,-0.6235310490678561,-0.7177615370892623,-0.08967050071108885,2.827512784417395,-0.2911692129463672,-0.4699677127277454,0.13188385952514886,0.49917415125399284,-0.5003402500028168,-0.5003402500028168,2.2206204495029636,0.7228043903765459
| 2,702
|
Lipid binding
| 39
| 122
| 3.590571
| 0.00033
|
O00560,Q8NCC3,Q9Y5X3,O00264,O94788,P61916,A0FGR8,P60903,Q15067,Q14108,P45880,O15118,O15020,P21796,Q13432,P38435,P28070,P30536,Q9BQE5,Q99623,P50897,Q01082,Q9H6U6,P07602,O15173,Q9NQZ5,Q9UNZ2,O60443,Q8WTV0,P04062,O15254,O14773,Q9H4L5,A6NIH7,Q9H0H5,P35080,O60313,P11717,Q9Y4G8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
130,134,406,255,8,142,389,397,274,19,23,24,285,31,161,413,159,412,37,436,52,427,185,57,187,60,328,65,69,443,72,201,100,101,102,365,363,120,254
|
389,101,255,1973,790,2691,130,555,201,1411,285,24,187,72,1660,815,1493,363,65,928,442,1496,557,8,664,1555,443,583,968,560,57,1177,820,2562,2563,765,892,1097,822,120,2597,895,1716,31,669,860,2387,159,1563,2361,1774,412,1776,365,1879,413,23,2656,1722,2193,52,738,2367,1675,1278,1676,1882,740,397,142,2267,427,1107,1320,1889,161,1428,1628,864,19,595,632,274,1329,2275,807,134,1391,69,777,1954,1641,2468,1852,1072,510,1643,436,2210,1854,1802,37,915,1648,2104,102,100,185,60,880,2316,576,2067,1759,1298,328,2071,2072,1597,254,1811,406
|
0.698408241052304,1.8592673659235324,1.0303037635203478,-0.4699677127277454,0.2659233011870234,-4.143157661047852,1.6176488501837785,0.473746678395286,1.255425828169697,-0.14649000038336524,0.9375444335085626,3.530739879481159,1.3428914236840213,2.2389705497371217,-0.2911692129463672,0.23937792178355133,-0.2039047156366997,0.747090864182487,2.329773449633904,0.15895673427969537,0.6245521818790327,-0.2039047156366997,0.473746678395286,4.492217400733412,0.37082842982646413,-0.2328390217993925,0.6245521818790327,0.4481994586006217,0.13188385952514886,0.473746678395286,2.436706104734128,-0.005531837066441173,0.23937792178355133,-1.1456872992127736,-1.1456872992127736,0.2923398612170866,0.18589586847145548,0.0498499651371408,0.23937792178355133,1.6994156728204817,-1.2842660323097124,0.18589586847145548,-0.32056824010222307,3.281841750088034,0.37082842982646413,0.2127025180887077,-0.8136248100970255,1.4502485272895491,-0.2328390217993925,-0.7814856320202566,-0.350125356105606,0.673901466516914,-0.350125356105606,0.747090864182487,-0.4097204049195783,0.673901466516914,3.587597806701549,-1.7982508277275122,-0.32056824010222307,-0.6235310490678561,2.678047917700652,0.31862879037972053,-0.7814856320202566,-0.2911692129463672,-0.06148029559266701,-0.2911692129463672,-0.4097204049195783,0.31862879037972053,0.698408241052304,1.5554884161976426,-0.6861725882485472,0.6492831048866388,0.0498499651371408,-0.08967050071108885,-0.4097204049195783,1.4502485272895491,-0.14649000038336524,-0.2619266677946719,0.2127025180887077,4.111237733873485,0.4481994586006217,0.4225314103597223,0.9841240598522195,-0.08967050071108885,-0.6861725882485472,0.2659233011870234,1.5970092420957023,-0.1180065861783075,2.275479978158442,0.2923398612170866,-0.43976167580769304,-0.2619266677946719,-0.9111757607706441,-0.37984219227896826,0.07733177575208161,0.5496741112974982,-0.2619266677946719,0.6492831048866388,-0.6235310490678561,-0.37984219227896826,-0.350125356105606,2.9887072724789827,0.18589586847145548,-0.2619266677946719,-0.5308810490428666,1.8592673659235324,1.8789142803170127,1.3645361307346424,2.3835119137294205,0.2127025180887077,-0.7177615370892623,0.473746678395286,-0.5003402500028168,-0.32056824010222307,-0.06148029559266701,0.8431585826801586,-0.5003402500028168,-0.5003402500028168,-0.2328390217993925,1.0532456836169948,-0.350125356105606,0.698408241052304
| 2,702
|
Lysosome
| 22
| 45
| 3.570707
| 0.000356
|
P16278,Q8NCC3,P61916,Q14108,O15118,P06280,P10619,P06865,P15586,P50897,P07602,P17900,O14773,Q9Y487,P11117,P54802,Q99538,P38571,Q15904,Q13510,P11279,P11717
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
128,134,142,19,24,149,163,168,174,52,57,70,201,78,83,98,99,233,234,111,236,120
|
1812,2475,2522,201,24,926,1978,762,443,582,149,168,57,1096,701,424,409,463,163,83,236,120,174,128,70,268,233,52,98,414,142,1994,1514,111,19,234,134,2699,529,99,878,880,1348,554,78
|
-0.37984219227896826,-0.9440776667177786,-1.0439690553345753,1.255425828169697,3.530739879481159,0.15895673427969537,-0.4699677127277454,0.2923398612170866,0.6245521818790327,0.4481994586006217,1.4925940643576996,1.4075642865122227,2.436706104734128,0.0498499651371408,0.3447912610633156,0.6492831048866388,0.673901466516914,0.5997077106006617,1.4289490678170462,2.1465741639128653,1.0988376535312658,1.6994156728204817,1.386093528320324,1.638208714171853,2.2572569188414064,1.0072634916981495,1.1214892721063172,2.678047917700652,1.8789142803170127,0.673901466516914,1.5554884161976426,-0.4699677127277454,-0.2039047156366997,1.7799433878907398,4.111237733873485,1.1214892721063172,1.5970092420957023,-5.288752019977064,0.5244829444562599,1.8789142803170127,0.2127025180887077,0.2127025180887077,-0.08967050071108885,0.49917415125399284,2.2206204495029636
| 2,702
|
Mental deterioration
| 17
| 82
| 3.52314
| 0.000426
|
P16278,P21964,P00403,P54802,Q9BQE5,P17900,P06865,Q9Y487,P61916,Q6Y7W6,Q13510,Q14108,P50897,O15118,P07602,P35637,Q9NQZ5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,34,35,98,37,70,168,78,142,110,111,19,52,24,57,155,60
|
790,24,926,363,816,2144,730,762,1415,648,699,35,443,2383,210,168,57,1096,891,1667,1010,128,70,1769,499,1717,34,345,2152,1719,1985,155,898,1780,1469,1569,796,2085,2394,52,2332,2086,98,2088,1882,142,627,1994,417,1838,1787,1110,2650,1021,111,19,944,2273,805,1118,2547,1028,110,2572,1159,1744,1746,2610,956,2593,1911,1644,37,2520,1918,60,1403,880,1041,788,2495,78
|
0.2659233011870234,3.530739879481159,0.15895673427969537,0.747090864182487,0.23937792178355133,-0.5924746168808616,0.31862879037972053,0.2923398612170866,-0.14649000038336524,0.39674143767950243,0.3447912610633156,3.1141580717849924,0.6245521818790327,-0.8136248100970255,1.2333342498208812,1.4075642865122227,2.436706104734128,0.0498499651371408,0.18589586847145548,-0.2911692129463672,0.10467597056101892,1.638208714171853,2.2572569188414064,-0.350125356105606,0.5496741112974982,-0.32056824010222307,3.1296283127460667,0.7953385242734627,-0.5924746168808616,-0.32056824010222307,-0.4699677127277454,1.4714633126430223,0.18589586847145548,-0.350125356105606,-0.17512221304650355,-0.2328390217993925,0.2659233011870234,-0.5308810490428666,-0.8136248100970255,2.678047917700652,-0.7495318851344548,-0.5308810490428666,1.8789142803170127,-0.5308810490428666,-0.4097204049195783,1.5554884161976426,0.4225314103597223,-0.4699677127277454,0.673901466516914,-0.37984219227896826,-0.350125356105606,0.0498499651371408,-1.6840786597335329,0.10467597056101892,1.7799433878907398,4.111237733873485,0.15895673427969537,-0.6861725882485472,0.2659233011870234,0.0498499651371408,-1.0776690173461208,0.10467597056101892,1.7998858840313976,-1.1800104648843361,0.02222921008355008,-0.32056824010222307,-0.32056824010222307,-1.3194551620520436,0.15895673427969537,-1.2492972789568666,-0.4097204049195783,-0.2619266677946719,2.9887072724789827,-1.0104720506565676,-0.4097204049195783,2.3835119137294205,-0.1180065861783075,0.2127025180887077,0.10467597056101892,0.2923398612170866,-0.9440776667177786,2.2206204495029636
| 2,702
|
Transporters
| 81
| 336
| 3.472272
| 0.000516
|
Q8N766,Q6NT16,Q9UKV3,O43772,Q8IXU6,Q93050,Q99720,Q8TB61,Q14108,P24390,P45880,O15118,Q5BJF2,Q5VW38,P00403,Q70HW3,Q6N075,P07602,O15260,Q9NQZ5,O60443,Q8WTV0,Q6P4A7,O75844,Q9H2H9,P41440,P11717,O00560,Q9BPX6,P61916,Q8TCT8,Q8NB49,Q9C0H2,Q9H2D1,P08183,P53985,Q8NFH4,Q9BUN8,P40855,Q15070,Q15904,P11279,O14786,O96005,Q9HD20,O15439,P20645,Q13190,Q12769,P80723,Q96JJ7,P52292,Q96PC5,Q07065,P53680,O15397,Q9UBV2,P02786,Q9NRR5,O60313,Q9BVL2,P55735,Q9H814,A0FGR8,P60903,P12270,P61421,P09497,P09496,Q9NR77,Q6ZXV5,O60637,Q9HD26,Q9BTX1,O43865,Q16891,P13073,Q96L92,Q96NB2,Q8N1F7,Q9UBX3
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
527,7,533,10,12,529,14,528,19,21,23,24,28,30,35,49,58,57,59,60,65,69,75,74,84,115,120,130,139,142,144,146,165,184,189,192,212,215,223,224,234,236,242,243,252,267,268,269,280,295,307,300,324,320,318,313,351,343,362,363,385,380,402,389,397,394,414,409,424,453,448,441,470,468,460,485,477,510,511,506,516
|
389,1549,1925,1867,614,1550,1352,790,2322,130,1258,1926,1975,242,1868,1355,24,2183,2476,1869,59,313,267,1359,814,926,1978,10,1131,460,363,2075,65,928,441,1360,1495,888,2353,2290,1456,2185,557,763,889,74,2575,965,2250,664,1555,1092,818,1264,1009,581,2658,1711,243,699,35,1874,343,2383,583,2414,1266,1047,1875,764,968,1462,1048,619,1220,560,57,820,189,969,1416,424,409,1268,2669,1097,236,120,1980,1098,394,477,2607,1669,702,1770,1503,268,649,823,1772,2257,1717,1417,21,1463,1719,1776,1673,2688,766,2327,898,1938,1879,1780,1611,1179,223,115,23,1721,2264,1940,1941,1674,1421,2394,1276,590,900,738,1422,1832,2042,300,1423,1227,318,192,1279,1943,1991,1882,380,1058,1509,705,2334,397,2335,1318,414,1680,2623,142,2126,628,1726,652,2301,2502,2566,1837,295,2662,2127,1786,1994,1107,1471,974,320,1108,902,1230,1514,280,1626,679,269,2445,2591,1378,19,2305,595,1473,1738,224,1474,596,1893,1686,234,1026,1379,485,1288,28,1527,545,1790,30,1329,58,7,2052,713,2053,75,1949,448,49,525,682,12,806,2408,807,506,836,527,146,948,1638,1030,212,1391,716,1479,528,2466,144,1586,992,1797,69,1242,1480,912,1031,872,873,529,2449,1481,1244,2310,1852,875,955,2469,307,1074,510,511,841,324,1440,956,639,1034,14,753,640,139,781,915,468,2010,215,1482,385,1341,1342,878,2104,2136,165,1038,184,84,1915,1293,1916,402,1294,1535,608,2019,252,470,1702,60,453,1650,362,2381,1538,880,609,1296,1254,642,1654,351,516,2494,611,919,2021,1348,575,1213,812,533,1042,2176,724,1705,2023,1215,2243,2071,1128,1810,1447,1490,1407,1707,1084,1761,2616,697,789
|
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| 2,702
|
Endoplasmic reticulum
| 116
| 409
| 3.469871
| 0.000521
|
O60506,P30519,Q8IV08,Q8N766,Q9BVK6,Q8TB61,Q99720,P48723,P07099,Q14108,Q9UMX5,P24390,O75718,Q5JRA6,O15118,Q16850,Q5BJF2,Q92542,Q8WXH0,Q9UQB8,Q9BQE5,O14579,P48449,Q96LJ7,Q9H6V9,P37268,O15260,Q32P28,Q9UBV8,O75844,Q15293,O15460,Q9H4L5,O00584,Q6Y7W6,Q13510,Q15392,Q8N2K0,O60725,Q14257,P80303,O00560,Q70UQ0,Q9NZ08,O60568,P09601,P61916,Q8TCT8,Q9Y282,Q8NB49,Q9NWM8,P43307,P10619,Q6P1A2,O95487,Q9H089,P13674,O43852,O15173,Q86XL3,O95197,Q9BUN8,Q9Y680,Q9BTY2,Q15904,Q01105,Q02818,Q9HD20,Q04323,O00264,Q13190,Q92791,Q96HY6,Q96JJ7,P52292,Q9P2W9,Q9Y5M8,Q12768,Q96PC5,Q07065,O43390,Q9BRR6,Q9UBV2,Q13217,O95456,O95674,Q14739,Q9NRR5,Q7Z4H8,Q9P2K2,P50402,P55735,P10321,Q6NUM9,A0FGR8,Q9P2E9,Q6NUQ4,P38435,P30536,Q15084,P39687,Q14318,Q9Y3E0,Q6ZXV5,Q13641,P14314,P04062,O43865,Q9H2J4,Q14534,P26885,P18031,Q08AM6,Q96AY3,Q9NQC3,Q8NBM4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
496,3,4,527,531,528,14,519,18,19,20,21,518,545,24,26,28,548,547,32,37,535,43,50,51,53,59,68,77,74,82,89,100,103,110,111,112,113,114,116,118,130,133,135,136,137,142,144,145,146,153,160,163,164,167,171,173,179,187,206,214,215,221,230,234,238,244,252,259,255,269,272,276,307,300,310,312,308,324,320,314,336,351,348,340,341,359,362,361,372,367,380,376,400,389,423,419,413,412,432,426,430,457,448,446,444,443,460,491,484,480,479,482,509,514,507
|
389,1658,255,614,790,2143,130,103,1301,535,1975,555,1449,791,1927,24,187,1869,59,727,2074,1871,89,2184,1928,314,1359,2113,926,179,460,1601,496,136,114,1412,2353,2225,557,762,1497,518,74,2575,2032,2250,1663,855,664,1092,1498,1415,214,1264,581,340,648,1557,167,819,341,618,2382,930,1219,2586,443,2414,1266,1047,1875,968,2356,1220,18,858,2293,2325,732,137,821,376,163,2146,667,173,444,2227,561,1051,702,479,1502,895,2256,2516,669,860,2415,2035,1053,21,1562,2081,2116,480,2388,2553,2565,671,1718,1563,2191,2260,824,538,734,3,1365,412,2118,2390,1366,2529,2037,766,1566,2416,53,413,1179,426,1612,1569,160,2649,2155,2437,1940,1723,43,2500,519,2193,2330,1941,1674,1421,2394,367,1016,1057,1724,1832,1180,300,1372,1277,2044,2368,1834,1882,1572,740,380,1058,2334,674,2546,1785,2335,1280,1425,2371,2124,1680,2623,142,2200,2441,2600,2463,1228,1281,1885,628,2203,2373,2301,769,118,1993,2569,941,2127,1573,238,1683,654,244,2629,2602,259,677,2570,320,482,828,862,308,1626,630,1516,1284,1996,742,269,348,111,2445,446,829,19,116,430,484,1735,359,1473,2271,1737,1738,1521,432,82,1287,596,112,2274,1632,710,1893,1997,907,1846,804,234,1379,26,1380,2309,68,746,28,1527,545,2096,2097,1476,2052,400,982,419,164,2053,1850,773,110,448,133,1897,361,1239,986,833,206,1240,834,4,870,806,2208,113,836,1159,527,1068,146,507,750,637,1795,716,1796,528,2466,2101,144,717,1586,1905,992,1195,1196,547,548,1070,1954,1198,272,872,1071,1695,1481,1244,2310,509,1395,2666,955,276,307,1245,50,324,1591,639,1909,2593,14,1801,780,2507,37,336,1037,915,1443,230,215,1482,2620,531,2104,171,1038,605,1079,491,1916,100,2611,51,2451,958,2109,2019,252,1701,1702,514,2138,362,787,1402,1040,153,1651,1347,2173,135,1253,609,1296,423,1595,372,310,882,660,642,351,77,611,2021,1923,643,2412,2176,20,2495,1004,1760,32,145,2243,2179,2319,1128,457,2244,1447,1864,312,2673,726,1548,221,2246
|
0.698408241052304,-0.2911692129463672,1.0303037635203478,0.4225314103597223,0.2659233011870234,-0.5924746168808616,1.6176488501837785,1.8395473434978173,-0.08967050071108885,0.49917415125399284,-0.4699677127277454,0.473746678395286,-0.17512221304650355,0.2659233011870234,-0.43976167580769304,3.530739879481159,1.3428914236840213,-0.4097204049195783,2.419034532533944,0.31862879037972053,-0.5308810490428666,-0.4097204049195783,2.0335184987881214,-0.6235310490678561,-0.43976167580769304,0.8431585826801586,-0.1180065861783075,-0.5615918989070766,0.15895673427969537,1.3645361307346424,0.5997077106006617,-0.2619266677946719,0.5496741112974982,1.5762892971839588,1.7398321727024608,-0.14649000038336524,-0.7814856320202566,-0.654763070997487,0.473746678395286,0.2923398612170866,-0.2039047156366997,0.5244829444562599,2.2206204495029636,-1.2145462814230732,-0.5003402500028168,-0.6861725882485472,-0.2911692129463672,0.2127025180887077,0.37082842982646413,0.0498499651371408,-0.2039047156366997,-0.14649000038336524,1.2111511761503668,-0.06148029559266701,0.4481994586006217,0.7953385242734627,0.39674143767950243,-0.2328390217993925,1.4075642865122227,0.23937792178355133,0.7953385242734627,0.4225314103597223,-0.8136248100970255,0.15895673427969537,-0.03343454335768025,-1.2492972789568666,0.6245521818790327,-0.8459514851409792,-0.06148029559266701,0.07733177575208161,-0.4097204049195783,0.13188385952514886,-0.7814856320202566,-0.03343454335768025,4.111237733873485,0.2127025180887077,-0.7177615370892623,-0.7495318851344548,0.31862879037972053,1.5762892971839588,0.23937792178355133,0.7228043903765459,1.4289490678170462,-0.5924746168808616,0.37082842982646413,1.386093528320324,0.6245521818790327,-0.654763070997487,0.473746678395286,0.07733177575208161,0.3447912610633156,0.5747486913303033,-0.2039047156366997,0.18589586847145548,-0.6861725882485472,-1.0104720506565676,0.37082842982646413,0.2127025180887077,-0.8459514851409792,-0.5003402500028168,0.07733177575208161,3.6717230671513654,-0.2328390217993925,-0.5308810490428666,-0.5615918989070766,0.5747486913303033,-0.8136248100970255,-1.1115742979561345,-1.1456872992127736,0.37082842982646413,-0.32056824010222307,-0.2328390217993925,-0.6235310490678561,-0.6861725882485472,0.23937792178355133,0.49917415125399284,0.31862879037972053,5.249303056100748,-0.1180065861783075,0.673901466516914,-0.5615918989070766,-0.8136248100970255,-0.1180065861783075,-1.0439690553345753,-0.5003402500028168,0.2923398612170866,-0.2328390217993925,-0.8459514851409792,2.6102209682067175,0.673901466516914,-0.005531837066441173,0.6492831048866388,-0.2619266677946719,-0.2328390217993925,1.4502485272895491,-1.6840786597335329,-0.5924746168808616,-0.8784677570852006,-0.43976167580769304,-0.32056824010222307,2.827512784417395,-0.977175681919584,0.5244829444562599,-0.6235310490678561,-0.7495318851344548,-0.43976167580769304,-0.2911692129463672,-0.14649000038336524,-0.8136248100970255,0.747090864182487,0.10467597056101892,0.07733177575208161,-0.32056824010222307,-0.37984219227896826,-0.005531837066441173,0.890558218300318,-0.1180065861783075,-0.06148029559266701,-0.5003402500028168,-0.7814856320202566,-0.37984219227896826,-0.4097204049195783,-0.2328390217993925,0.31862879037972053,0.7228043903765459,0.07733177575208161,-0.7495318851344548,0.37082842982646413,-1.0776690173461208,-0.350125356105606,-0.7495318851344548,-0.06148029559266701,-0.14649000038336524,-0.7814856320202566,-0.5615918989070766,-0.2911692129463672,-1.4263717244472445,1.5554884161976426,-0.6235310490678561,-0.8784677570852006,-1.2842660323097124,-0.9111757607706441,-0.03343454335768025,-0.06148029559266701,-0.4097204049195783,0.4225314103597223,-0.6235310490678561,-0.7814856320202566,-0.7177615370892623,0.2923398612170866,1.7196623603455143,-0.4699677127277454,-1.1800104648843361,0.15895673427969537,-0.5615918989070766,-0.2328390217993925,1.0988376535312658,-0.2911692129463672,0.39674143767950243,1.0760900505966375,-1.4624695189023518,-1.2842660323097124,1.0303037635203478,0.37082842982646413,-1.1800104648843361,0.8431585826801586,0.5747486913303033,0.23937792178355133,0.2127025180887077,0.8669105116207638,-0.2619266677946719,0.4225314103597223,-0.2039047156366997,-0.06148029559266701,-0.4699677127277454,0.31862879037972053,1.0072634916981495,0.7953385242734627,1.7799433878907398,-0.8784677570852006,0.6245521818790327,0.23937792178355133,4.111237733873485,1.7398321727024608,0.6492831048866388,0.5747486913303033,-0.32056824010222307,0.7712686001756313,-0.17512221304650355,-0.6861725882485472,-0.32056824010222307,-0.32056824010222307,-0.2039047156366997,0.6492831048866388,2.183727349455117,-0.06148029559266701,0.4481994586006217,1.7599256653622593,-0.6861725882485472,-0.2619266677946719,0.3447912610633156,-0.4097204049195783,-0.4699677127277454,0.18589586847145548,-0.37984219227896826,0.2659233011870234,1.1214892721063172,-0.1180065861783075,3.487680492801992,-0.1180065861783075,-0.7177615370892623,2.293640144931326,0.31862879037972053,3.371065258354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| 2,702
|
Mitochondrion organization
| 47
| 157
| 3.30554
| 0.000948
|
P02545,Q99595,Q9NS69,Q16706,P50542,Q9P0J0,Q8N4H5,Q9UDX5,P14406,P45880,P21796,Q5JRX3,Q16718,Q04837,Q9NX63,P30536,O95831,Q99623,Q96HS1,O96000,O75880,Q9Y2R0,Q7L592,Q13505,Q9BVV7,Q9NQG6,P04062,Q9NUQ9,Q69YU5,Q99496,O75431,Q15388,P55786,O14737,O75153,P02786,Q15070,Q9Y5J7,Q16891,P11233,Q9BUK6,O95139,O60313,P48507,Q7Z406,Q6DKK2,O43676
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
374,5,6,132,379,532,138,148,22,23,31,546,544,542,290,412,39,436,572,172,296,56,321,64,451,195,443,337,204,335,461,86,92,217,222,343,224,493,485,476,108,474,363,366,505,126,127
|
1351,1812,2142,790,217,852,729,127,925,363,222,2496,1361,730,461,2324,646,1135,296,966,474,856,1415,818,1931,2525,39,172,699,374,343,443,792,1266,1048,1768,1311,2357,765,476,1980,22,1270,587,31,2565,1272,1013,2362,2459,412,1776,2084,1317,1465,1567,1466,2039,1569,23,366,1941,1570,379,1057,1832,1017,1277,92,674,1375,2566,1059,542,1110,64,1232,224,977,86,1026,1379,132,544,1998,485,1190,867,546,1118,204,126,774,2572,321,505,2343,2465,682,989,1692,2277,990,138,1159,2235,1743,2101,1640,809,572,956,1247,335,2593,1076,5,436,1644,780,844,2520,2010,108,1482,451,997,1204,2429,606,607,785,195,6,2381,337,757,961,290,1808,532,1653,148,1297,694,576,2023,56,2433,2071,2320,644,1490,493,884,697,1971
|
-0.1180065861783075,-0.37984219227896826,-0.5924746168808616,0.2659233011870234,1.1888758808001145,0.2127025180887077,0.31862879037972053,1.638208714171853,0.15895673427969537,0.747090864182487,1.1665076288666967,-0.977175681919584,-0.1180065861783075,0.31862879037972053,0.5997077106006617,-0.7495318851344548,0.39674143767950243,0.02222921008355008,0.890558218300318,0.13188385952514886,0.5747486913303033,0.2127025180887077,-0.14649000038336524,0.23937792178355133,-0.43976167580769304,-1.0439690553345753,2.9408710467958437,1.386093528320324,0.3447912610633156,0.7228043903765459,0.7953385242734627,0.6245521818790327,0.2659233011870234,-0.06148029559266701,0.07733177575208161,-0.350125356105606,-0.08967050071108885,-0.7814856320202566,0.2923398612170866,0.5747486913303033,-0.4699677127277454,3.643834047397023,-0.06148029559266701,0.4481994586006217,3.281841750088034,-1.1456872992127736,-0.06148029559266701,0.10467597056101892,-0.7814856320202566,-0.9111757607706441,0.673901466516914,-0.350125356105606,-0.5308810490428666,-0.08967050071108885,-0.17512221304650355,-0.2328390217993925,-0.17512221304650355,-0.5003402500028168,-0.2328390217993925,3.587597806701549,0.747090864182487,-0.43976167580769304,-0.2328390217993925,0.7228043903765459,0.07733177575208161,-0.37984219227896826,0.10467597056101892,-0.06148029559266701,2.0144383197469633,0.37082842982646413,-0.1180065861783075,-1.1456872992127736,0.07733177575208161,0.49917415125399284,0.0498499651371408,2.3477474020211564,-0.03343454335768025,1.1665076288666967,0.13188385952514886,2.0714733698385936,0.10467597056101892,-0.1180065861783075,1.5970092420957023,0.49917415125399284,-0.4699677127277454,0.5747486913303033,-0.005531837066441173,0.2127025180887077,0.49917415125399284,0.0498499651371408,1.255425828169697,1.6586894203500797,0.2923398612170866,-1.1800104648843361,0.8431585826801586,0.5496741112974982,-0.7495318851344548,-0.9111757607706441,0.37082842982646413,0.13188385952514886,-0.2911692129463672,-0.6861725882485472,0.13188385952514886,1.5762892971839588,0.02222921008355008,-0.654763070997487,-0.32056824010222307,-0.5308810490428666,-0.2619266677946719,0.2659233011870234,0.473746678395286,0.15895673427969537,-0.03343454335768025,0.8193015508006276,-1.2492972789568666,0.07733177575208161,5.198120334434664,0.6492831048866388,-0.2619266677946719,0.2923398612170866,0.23937792178355133,-1.0104720506565676,-0.4699677127277454,1.8197536917866635,-0.17512221304650355,0.6245521818790327,0.13188385952514886,-0.005531837066441173,-0.8459514851409792,0.4481994586006217,0.4481994586006217,0.2923398612170866,1.2993373623907043,4.890473754334426,-0.7814856320202566,0.8193015508006276,0.31862879037972053,0.15895673427969537,0.9375444335085626,-0.350125356105606,0.5244829444562599,-0.2619266677946719,1.5136414157872253,-0.06148029559266701,0.37082842982646413,0.473746678395286,-0.4699677127277454,2.489366453233105,-0.8459514851409792,-0.5003402500028168,-0.7177615370892623,0.4225314103597223,-0.17512221304650355,0.5747486913303033,0.2127025180887077,0.37082842982646413,-0.43976167580769304
| 2,702
|
Cognitive impairment
| 27
| 141
| 3.303886
| 0.000954
|
P16278,Q9NZ08,Q9Y263,P61916,Q99720,Q14108,O15118,P06280,P35637,P21964,P00403,Q9BQE5,O95831,P06865,P50897,Q9Y2R0,P07602,Q13144,Q9NQZ5,P17900,Q9Y487,P04350,Q9BVA1,P54802,Q6Y7W6,Q13510,Q6DKK2
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,135,140,142,14,19,24,149,155,34,35,37,39,168,52,56,57,181,60,70,78,210,220,98,110,111,126
|
790,285,24,926,363,816,2144,730,1456,762,1415,648,39,699,35,443,2383,210,1266,149,168,315,57,1096,2251,891,1667,1010,2669,1980,128,70,1769,2385,499,2257,1716,1717,34,2415,345,2152,1719,1985,1776,155,898,1780,223,1612,1469,1569,796,1056,1880,2194,2085,2394,379,52,2332,2086,1833,1782,98,2088,1882,705,2486,1680,142,627,1994,427,1147,2399,417,1838,1787,1110,1888,2650,181,1021,348,111,19,944,2375,1324,865,2273,710,2404,2446,805,1582,1118,126,2547,1634,1028,110,983,2572,333,1159,507,1242,1744,1746,601,2610,956,335,2593,1911,1644,14,37,2520,220,1918,60,641,1403,135,880,1041,788,1756,2676,812,2495,696,140,56,78,644,2595,1084
|
0.2659233011870234,0.9375444335085626,3.530739879481159,0.15895673427969537,0.747090864182487,0.23937792178355133,-0.5924746168808616,0.31862879037972053,-0.17512221304650355,0.2923398612170866,-0.14649000038336524,0.39674143767950243,2.9408710467958437,0.3447912610633156,3.1141580717849924,0.6245521818790327,-0.8136248100970255,1.2333342498208812,-0.06148029559266701,1.4925940643576996,1.4075642865122227,0.8431585826801586,2.436706104734128,0.0498499651371408,-0.6861725882485472,0.18589586847145548,-0.2911692129463672,0.10467597056101892,-2.0740082524478405,-0.4699677127277454,1.638208714171853,2.2572569188414064,-0.350125356105606,-0.8136248100970255,0.5496741112974982,-0.6861725882485472,-0.32056824010222307,-0.32056824010222307,3.1296283127460667,-0.8459514851409792,0.7953385242734627,-0.5924746168808616,-0.32056824010222307,-0.4699677127277454,-0.350125356105606,1.4714633126430223,0.18589586847145548,-0.350125356105606,1.1665076288666967,-0.2619266677946719,-0.17512221304650355,-0.2328390217993925,0.2659233011870234,0.07733177575208161,-0.4097204049195783,-0.6235310490678561,-0.5308810490428666,-0.8136248100970255,0.7228043903765459,2.678047917700652,-0.7495318851344548,-0.5308810490428666,-0.37984219227896826,-0.350125356105606,1.8789142803170127,-0.5308810490428666,-0.4097204049195783,0.3447912610633156,-0.9440776667177786,-0.2911692129463672,1.5554884161976426,0.4225314103597223,-0.4699677127277454,0.6492831048866388,0.02222921008355008,-0.8136248100970255,0.673901466516914,-0.37984219227896826,-0.350125356105606,0.0498499651371408,-0.4097204049195783,-1.6840786597335329,1.3645361307346424,0.10467597056101892,0.7953385242734627,1.7799433878907398,4.111237733873485,0.15895673427969537,-0.7814856320202566,-0.08967050071108885,0.2127025180887077,-0.6861725882485472,0.3447912610633156,-0.8136248100970255,-0.8784677570852006,0.2659233011870234,-0.2328390217993925,0.0498499651371408,1.6586894203500797,-1.0776690173461208,-0.2619266677946719,0.10467597056101892,1.7998858840313976,0.13188385952514886,-1.1800104648843361,0.8193015508006276,0.02222921008355008,0.5496741112974982,-0.03343454335768025,-0.32056824010222307,-0.32056824010222307,0.4481994586006217,-1.3194551620520436,0.15895673427969537,0.8193015508006276,-1.2492972789568666,-0.4097204049195783,-0.2619266677946719,4.199796153109882,2.9887072724789827,-1.0104720506565676,1.1888758808001145,-0.4097204049195783,2.3835119137294205,0.4225314103597223,-0.1180065861783075,1.5970092420957023,0.2127025180887077,0.10467597056101892,0.2923398612170866,-0.32056824010222307,-2.1964381275798592,0.2659233011870234,-0.9440776667177786,0.37082842982646413,1.5762892971839588,2.489366453233105,2.2206204495029636,0.4225314103597223,-1.2492972789568666,0.07733177575208161
| 2,702
|
Secondary alcohol metabolic process
| 10
| 36
| 3.270637
| 0.001073
|
Q9BQE5,Q8WTV0,P48449,P61916,Q15392,P48735,P37268,O75874,O15118,Q16850
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
37,69,43,142,112,17,53,54,24,26
|
24,1929,557,54,2032,664,2586,443,1222,1713,1051,2190,53,2039,43,17,1615,2196,2297,142,2267,1229,2402,484,359,2050,112,1846,804,26,164,69,2169,37,660,455
|
3.530739879481159,-0.43976167580769304,0.473746678395286,2.558767311500275,-0.5003402500028168,0.37082842982646413,-1.2492972789568666,0.6245521818790327,-0.03343454335768025,-0.32056824010222307,0.07733177575208161,-0.6235310490678561,2.6102209682067175,-0.5003402500028168,2.827512784417395,4.123983608212495,-0.2619266677946719,-0.6235310490678561,-0.7177615370892623,1.5554884161976426,-0.6861725882485472,-0.03343454335768025,-0.8136248100970255,0.5747486913303033,0.7712686001756313,-0.5003402500028168,1.7599256653622593,-0.37984219227896826,0.2659233011870234,3.487680492801992,1.4289490678170462,2.275479978158442,-0.5924746168808616,2.9887072724789827,0.39674143767950243,0.6245521818790327
| 2,702
|
Pain
| 48
| 146
| 3.269951
| 0.001076
|
Q15165,P02545,Q9NZ08,P11310,P48735,Q14108,Q96HY6,Q12769,Q6UN15,P06280,P35637,Q8WXH0,P21964,P28070,Q14566,Q15056,Q13423,Q70HW3,Q03252,Q01082,O75874,P07602,O75477,Q9NR77,P53680,P14314,Q969G3,P04062,Q9UGP8,Q99496,O75844,P42892,Q8NFH4,Q9Y2U8,P23786,O15460,P22626,P14174,Q14739,Q9BUK6,P20700,Q13510,P50402,O60313,Q8N1F7,Q8NBM4,Q01844,Q92804
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
262,374,135,141,17,19,276,280,524,149,155,547,34,159,36,543,177,49,428,427,54,57,557,453,318,444,601,443,611,335,74,80,212,353,88,89,345,218,359,108,499,111,367,363,506,507,382,250
|
1351,790,1353,1175,727,2074,89,887,2648,363,557,964,74,54,1264,2188,2478,374,443,2577,1266,149,857,57,1096,1177,1666,891,1010,1097,141,1222,1980,218,444,1769,1502,2385,499,1716,1717,34,1052,2415,345,88,671,159,1719,2119,1776,1367,1937,155,936,1419,2460,2328,1468,80,796,1056,1369,17,2194,1615,367,900,738,2042,2395,1782,2368,318,1834,2088,1882,1572,705,2486,2335,1624,427,1147,382,1471,428,1839,2268,1149,280,1888,655,1021,1322,177,111,2093,19,944,2305,36,1735,359,632,680,543,262,2403,804,2404,1478,524,49,1691,506,635,507,212,1242,1744,1069,547,1031,2236,250,872,601,276,335,1911,1443,108,1341,1700,606,453,135,880,2316,611,1405,661,353,1864,1407
|
-0.1180065861783075,0.2659233011870234,-0.1180065861783075,-0.005531837066441173,0.31862879037972053,-0.5308810490428666,2.0335184987881214,0.18589586847145548,-1.6840786597335329,0.747090864182487,0.473746678395286,0.13188385952514886,2.2206204495029636,2.558767311500275,-0.06148029559266701,-0.6235310490678561,-0.9440776667177786,0.7228043903765459,0.6245521818790327,-1.2145462814230732,-0.06148029559266701,1.4925940643576996,0.2127025180887077,2.436706104734128,0.0498499651371408,-0.005531837066441173,-0.2911692129463672,0.18589586847145548,0.10467597056101892,0.0498499651371408,1.5554884161976426,-0.03343454335768025,-0.4699677127277454,1.1888758808001145,0.6245521818790327,-0.350125356105606,-0.2039047156366997,-0.8136248100970255,0.5496741112974982,-0.32056824010222307,-0.32056824010222307,3.1296283127460667,0.07733177575208161,-0.8459514851409792,0.7953385242734627,2.0525300254302943,0.37082842982646413,1.4502485272895491,-0.32056824010222307,-0.5615918989070766,-0.350125356105606,-0.1180065861783075,-0.43976167580769304,1.4714633126430223,0.15895673427969537,-0.14649000038336524,-0.9111757607706441,-0.7495318851344548,-0.17512221304650355,2.202206192643275,0.2659233011870234,0.07733177575208161,-0.1180065861783075,4.123983608212495,-0.6235310490678561,-0.2619266677946719,0.747090864182487,0.18589586847145548,0.31862879037972053,-0.5003402500028168,-0.8136248100970255,-0.350125356105606,-0.7814856320202566,0.8431585826801586,-0.37984219227896826,-0.5308810490428666,-0.4097204049195783,-0.2328390217993925,0.3447912610633156,-0.9440776667177786,-0.7495318851344548,-0.2619266677946719,0.6492831048866388,0.02222921008355008,0.7228043903765459,-0.17512221304650355,0.6492831048866388,-0.37984219227896826,-0.6861725882485472,0.02222921008355008,0.9608846498386505,-0.4097204049195783,0.39674143767950243,0.10467597056101892,-0.08967050071108885,1.386093528320324,1.7799433878907398,-0.5308810490428666,4.111237733873485,0.15895673427969537,-0.7177615370892623,3.0045553572629977,-0.32056824010222307,0.7712686001756313,0.4225314103597223,0.37082842982646413,0.49917415125399284,1.0303037635203478,-0.8136248100970255,0.2659233011870234,-0.8136248100970255,-0.17512221304650355,0.5244829444562599,2.745005746127423,-0.2911692129463672,0.5496741112974982,0.4225314103597223,0.5496741112974982,1.2333342498208812,-0.03343454335768025,-0.32056824010222307,0.07733177575208161,0.49917415125399284,0.10467597056101892,-0.654763070997487,1.0532456836169948,0.2127025180887077,0.4481994586006217,0.9841240598522195,0.8193015508006276,-0.4097204049195783,-0.14649000038336524,1.8197536917866635,-0.08967050071108885,-0.2911692129463672,0.4481994586006217,0.6245521818790327,1.5970092420957023,0.2127025180887077,-0.7177615370892623,0.4481994586006217,-0.1180065861783075,0.39674143767950243,0.7953385242734627,-0.37984219227896826,-0.1180065861783075
| 2,702
|
Alpha/Beta hydrolase fold [IPR029058]
| 9
| 21
| 3.254797
| 0.001135
|
P42785,P10619,Q8NCC3,Q9H3G5,Q8N2K0,P07099,Q9H6V9,P50897,Q9HB40
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
0,163,134,44,113,18,51,52,29
|
1497,2291,18,163,2146,2114,233,0,2296,2194,52,1581,332,113,134,44,51,29,847,2064,1491
|
-0.2039047156366997,-0.7177615370892623,4.111237733873485,1.4289490678170462,-0.5924746168808616,-0.5615918989070766,1.1214892721063172,6.217718739388483,-0.7177615370892623,-0.6235310490678561,2.678047917700652,-0.2328390217993925,0.8193015508006276,1.7599256653622593,1.5970092420957023,2.827512784417395,2.7283466065358986,3.341494967883903,0.23937792178355133,-0.5003402500028168,-0.17512221304650355
| 2,702
|
Receptor
| 17
| 33
| 3.240337
| 0.001194
|
Q5KU26,Q14739,Q8WTV0,Q9NS69,O00264,Q9Y2W1,P20645,P11717,Q99720,P11279,O14786,Q14108,P24390,Q9Y5M8,O15118,O15173,P02786
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
66,359,69,6,255,405,268,120,14,236,242,19,21,312,24,187,343
|
255,242,663,24,187,343,619,1220,2325,2145,821,2358,236,120,2552,268,21,766,2566,975,19,359,1686,66,69,2467,436,14,6,643,405,312,2220
|
1.0303037635203478,1.0760900505966375,0.37082842982646413,3.530739879481159,1.3428914236840213,0.7953385242734627,0.4225314103597223,-0.03343454335768025,-0.7495318851344548,-0.5924746168808616,0.23937792178355133,-0.7814856320202566,1.0988376535312658,1.6994156728204817,-1.1115742979561345,1.0072634916981495,3.6717230671513654,0.2923398612170866,-1.1456872992127736,0.13188385952514886,4.111237733873485,0.7712686001756313,-0.2911692129463672,2.329773449633904,2.275479978158442,-0.9111757607706441,0.6492831048866388,4.199796153109882,4.890473754334426,0.4225314103597223,0.698408241052304,0.8669105116207638,-0.6235310490678561
| 2,702
|
Organic hydroxy compound metabolic process
| 19
| 94
| 3.232496
| 0.001227
|
Q9BY49,O94788,P61916,P48735,O15118,Q16850,P30837,P21964,Q6P1A2,Q9BQE5,P48449,P43304,P37268,O75874,Q8WTV0,Q99538,Q9H4L5,Q13510,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,8,142,17,24,26,33,34,164,37,43,42,53,54,69,99,100,111,112
|
2585,24,727,2074,1929,557,889,54,2032,8,664,2188,700,2586,2077,443,1266,375,2292,2079,1222,2597,1713,2294,2384,1051,364,2359,34,669,860,2190,1463,2483,33,53,413,233,2039,42,43,17,1615,2196,2332,2086,1180,2297,2045,2370,169,142,2267,466,1229,2399,1110,111,2685,2402,484,359,2624,2050,112,304,1846,804,1740,26,400,164,1068,2132,69,1439,956,1643,2593,99,1644,2169,37,129,100,2109,1959,785,2172,660,455,2179,254,2413
|
-1.2492972789568666,3.530739879481159,0.31862879037972053,-0.5308810490428666,-0.43976167580769304,0.473746678395286,0.18589586847145548,2.558767311500275,-0.5003402500028168,4.492217400733412,0.37082842982646413,-0.6235310490678561,0.3447912610633156,-1.2492972789568666,-0.5308810490428666,0.6245521818790327,-0.06148029559266701,0.7228043903765459,-0.7177615370892623,-0.5308810490428666,-0.03343454335768025,-1.2842660323097124,-0.32056824010222307,-0.7177615370892623,-0.8136248100970255,0.07733177575208161,0.747090864182487,-0.7814856320202566,3.1296283127460667,0.37082842982646413,0.2127025180887077,-0.6235310490678561,-0.17512221304650355,-0.9440776667177786,3.160430985084966,2.6102209682067175,0.673901466516914,1.1214892721063172,-0.5003402500028168,2.827512784417395,2.827512784417395,4.123983608212495,-0.2619266677946719,-0.6235310490678561,-0.7495318851344548,-0.5308810490428666,-0.005531837066441173,-0.7177615370892623,-0.5003402500028168,-0.7814856320202566,1.4075642865122227,1.5554884161976426,-0.6861725882485472,0.5997077106006617,-0.03343454335768025,-0.8136248100970255,0.0498499651371408,1.7799433878907398,-2.8054927922613717,-0.8136248100970255,0.5747486913303033,0.7712686001756313,-1.4263717244472445,-0.5003402500028168,1.7599256653622593,0.890558218300318,-0.37984219227896826,0.2659233011870234,-0.32056824010222307,3.487680492801992,0.698408241052304,1.4289490678170462,0.07733177575208161,-0.5615918989070766,2.275479978158442,-0.14649000038336524,0.15895673427969537,-0.2619266677946719,-1.2492972789568666,1.8789142803170127,-0.2619266677946719,-0.5924746168808616,2.9887072724789827,1.638208714171853,1.8789142803170127,-0.5308810490428666,-0.43976167580769304,0.2923398612170866,-0.5924746168808616,0.39674143767950243,0.6245521818790327,-0.5924746168808616,1.0532456836169948,-0.8136248100970255
| 2,702
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 8
| 28
| 3.231506
| 0.001231
|
P30519,Q32P28,O60568,P09601,P61457,Q8NB78,O15460,Q16850
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
3,68,136,137,169,55,89,26
|
2143,1301,89,1133,136,1552,1457,2382,858,137,173,1051,2361,3,169,654,1626,484,804,26,68,657,681,1156,55,422,2059,1657
|
-0.5924746168808616,-0.08967050071108885,2.0335184987881214,0.02222921008355008,1.5762892971839588,-0.2328390217993925,-0.17512221304650355,-0.8136248100970255,0.2127025180887077,1.5762892971839588,1.386093528320324,0.07733177575208161,-0.7814856320202566,5.249303056100748,1.4075642865122227,0.39674143767950243,-0.2619266677946719,0.5747486913303033,0.2659233011870234,3.487680492801992,2.293640144931326,0.39674143767950243,0.37082842982646413,0.02222921008355008,2.5415030973697146,0.673901466516914,-0.5003402500028168,-0.2619266677946719
| 2,702
|
Alcohol metabolic process
| 16
| 69
| 3.225437
| 0.001258
|
Q9BY49,P30837,Q6P1A2,Q9BQE5,Q8WTV0,O94788,P48449,P61916,P43304,Q13510,Q15392,P48735,P37268,O75874,O15118,Q16850
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,33,164,37,69,8,43,142,42,111,112,17,53,54,24,26
|
2585,24,727,2074,1929,557,54,2032,8,664,700,2586,443,375,1222,2597,1713,2294,2384,1051,2359,2190,33,53,2039,42,43,17,1615,2196,2332,2086,1180,2297,2370,169,142,2267,466,1229,2399,1110,111,2685,2402,484,359,2050,112,1846,804,1740,26,400,164,1068,2132,69,1439,2593,2169,37,129,2109,1959,2172,660,455,2179
|
-1.2492972789568666,3.530739879481159,0.31862879037972053,-0.5308810490428666,-0.43976167580769304,0.473746678395286,2.558767311500275,-0.5003402500028168,4.492217400733412,0.37082842982646413,0.3447912610633156,-1.2492972789568666,0.6245521818790327,0.7228043903765459,-0.03343454335768025,-1.2842660323097124,-0.32056824010222307,-0.7177615370892623,-0.8136248100970255,0.07733177575208161,-0.7814856320202566,-0.6235310490678561,3.160430985084966,2.6102209682067175,-0.5003402500028168,2.827512784417395,2.827512784417395,4.123983608212495,-0.2619266677946719,-0.6235310490678561,-0.7495318851344548,-0.5308810490428666,-0.005531837066441173,-0.7177615370892623,-0.7814856320202566,1.4075642865122227,1.5554884161976426,-0.6861725882485472,0.5997077106006617,-0.03343454335768025,-0.8136248100970255,0.0498499651371408,1.7799433878907398,-2.8054927922613717,-0.8136248100970255,0.5747486913303033,0.7712686001756313,-0.5003402500028168,1.7599256653622593,-0.37984219227896826,0.2659233011870234,-0.32056824010222307,3.487680492801992,0.698408241052304,1.4289490678170462,0.07733177575208161,-0.5615918989070766,2.275479978158442,-0.14649000038336524,-1.2492972789568666,-0.5924746168808616,2.9887072724789827,1.638208714171853,-0.5308810490428666,-0.43976167580769304,-0.5924746168808616,0.39674143767950243,0.6245521818790327,-0.5924746168808616
| 2,702
|
Mitochondrial transport
| 26
| 73
| 3.212003
| 0.001318
|
Q99595,Q9NS69,O75964,Q9P0J0,Q8N4H5,O43772,P45880,Q5JRX3,P30536,P06576,O95831,Q9UJZ1,Q9BVV7,Q96EK5,Q99496,Q9HAV7,O75431,Q15388,P23786,P56385,P55786,Q9Y5J7,O14737,Q15070,P56134,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
5,6,256,532,138,10,23,546,412,292,39,576,451,602,335,607,461,86,88,347,92,493,217,224,369,516
|
1351,217,852,729,10,461,2324,1136,256,966,2525,39,699,1266,1048,292,1768,1311,765,1980,587,88,621,896,2362,2459,412,2084,1015,2039,23,1370,1941,2394,1832,1277,92,369,347,1375,1110,224,86,1379,1190,867,546,713,2343,989,1692,138,1743,1640,602,956,335,5,780,451,1204,607,6,532,1653,516,812,576,2023,2071,1490,493,884
|
-0.1180065861783075,1.1888758808001145,0.2127025180887077,0.31862879037972053,4.396604319498196,0.5997077106006617,-0.7495318851344548,0.02222921008355008,1.0303037635203478,0.13188385952514886,-1.0439690553345753,2.9408710467958437,0.3447912610633156,-0.06148029559266701,0.07733177575208161,0.9141025725456303,-0.350125356105606,-0.08967050071108885,0.2923398612170866,-0.4699677127277454,0.4481994586006217,2.0525300254302943,0.4225314103597223,0.18589586847145548,-0.7814856320202566,-0.9111757607706441,0.673901466516914,-0.5308810490428666,0.10467597056101892,-0.5003402500028168,3.587597806701549,-0.1180065861783075,-0.43976167580769304,-0.8136248100970255,-0.37984219227896826,-0.06148029559266701,2.0144383197469633,0.747090864182487,0.7953385242734627,-0.1180065861783075,0.0498499651371408,1.1665076288666967,2.0714733698385936,-0.1180065861783075,-0.005531837066441173,0.2127025180887077,0.49917415125399284,0.3447912610633156,-0.7495318851344548,0.13188385952514886,-0.2911692129463672,1.5762892971839588,-0.32056824010222307,-0.2619266677946719,0.4481994586006217,0.15895673427969537,0.8193015508006276,5.198120334434664,0.2923398612170866,0.6245521818790327,-0.005531837066441173,0.4481994586006217,4.890473754334426,0.5244829444562599,-0.2619266677946719,0.5496741112974982,0.2659233011870234,0.473746678395286,-0.4699677127277454,-0.5003402500028168,-0.17512221304650355,0.5747486913303033,0.2127025180887077
| 2,702
|
Transporter
| 50
| 178
| 3.147282
| 0.001648
|
O00560,Q6NT16,P50542,O43772,Q9BVK6,Q93050,Q8TB61,Q8IXU6,O15439,Q13190,Q8NB49,P24390,Q12769,O95249,P61421,Q9BQE5,P09497,O95487,P06576,Q70HW3,P52292,Q9H2D1,Q9P2W9,P09496,Q12768,Q6N075,Q9UNZ2,P08183,P53985,P53680,P17900,Q8N2H4,O60749,O43760,Q9Y487,Q8NFH4,Q9H2H9,Q15388,P56385,Q15070,O95721,P56134,P11279,P41440,Q96NB2,Q8N1F7,Q9Y5K8,Q9UBX3,P55735,Q9HD45
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
130,7,379,10,531,529,528,12,267,269,146,21,280,279,414,37,409,167,292,49,300,184,310,424,308,58,328,189,192,318,70,199,442,73,78,212,84,86,347,224,104,369,236,115,511,506,388,516,380,265
|
1925,1410,1812,614,2322,130,1926,535,2522,1357,267,73,10,1131,615,1360,442,1412,888,2185,889,1136,1092,818,279,1264,1557,167,2658,104,699,764,968,1462,1048,292,189,969,424,409,2669,236,1980,1098,702,70,1503,823,1772,1417,21,621,896,1463,538,2688,2037,1015,1879,1780,115,1723,2193,1941,1421,379,1832,300,1423,2044,2368,318,192,1834,1279,1943,1944,380,369,347,705,414,1680,2200,1726,2127,1786,1994,1573,1471,1514,308,280,679,1516,269,1428,864,708,1473,224,1287,596,86,1686,58,7,713,2053,49,525,1239,2100,12,1158,506,199,146,1030,212,1479,528,992,1797,2057,1122,1196,912,2699,873,529,875,1956,511,1440,956,1123,1034,753,640,37,781,1749,531,1342,2136,1038,2379,184,84,1915,1294,608,265,880,1252,1296,2217,310,882,1254,516,1348,1213,812,1004,328,1705,1215,2319,1128,78,388,1598,1084,726,697,789
|
-0.43976167580769304,-0.14649000038336524,-0.37984219227896826,0.4225314103597223,-0.7495318851344548,1.6176488501837785,-0.43976167580769304,0.49917415125399284,-1.0439690553345753,-0.1180065861783075,1.0072634916981495,2.2389705497371217,4.396604319498196,0.02222921008355008,0.4225314103597223,-0.1180065861783075,0.6245521818790327,-0.14649000038336524,0.18589586847145548,-0.6235310490678561,0.18589586847145548,0.02222921008355008,0.0498499651371408,0.23937792178355133,0.9608846498386505,-0.06148029559266701,-0.2328390217993925,1.4075642865122227,-1.8368287909913394,1.8395473434978173,0.3447912610633156,0.2923398612170866,0.13188385952514886,-0.17512221304650355,0.07733177575208161,0.9141025725456303,1.3428914236840213,0.13188385952514886,0.6492831048866388,0.673901466516914,-2.0740082524478405,1.0988376535312658,-0.4699677127277454,0.0498499651371408,0.3447912610633156,2.2572569188414064,-0.2039047156366997,0.23937792178355133,-0.350125356105606,-0.14649000038336524,3.6717230671513654,0.4225314103597223,0.18589586847145548,-0.17512221304650355,0.49917415125399284,-3.1850832781614544,-0.5003402500028168,0.10467597056101892,-0.4097204049195783,-0.350125356105606,1.7398321727024608,-0.32056824010222307,-0.6235310490678561,-0.43976167580769304,-0.14649000038336524,0.7228043903765459,-0.37984219227896826,0.890558218300318,-0.14649000038336524,-0.5003402500028168,-0.7814856320202566,0.8431585826801586,1.3211587294181275,-0.37984219227896826,-0.06148029559266701,-0.43976167580769304,-0.43976167580769304,0.7228043903765459,0.747090864182487,0.7953385242734627,0.3447912610633156,0.673901466516914,-0.2911692129463672,-0.6235310490678561,-0.32056824010222307,-0.5615918989070766,-0.350125356105606,-0.4699677127277454,-0.2328390217993925,-0.17512221304650355,-0.2039047156366997,0.8669105116207638,0.9608846498386505,0.37082842982646413,-0.2039047156366997,1.0072634916981495,-0.14649000038336524,0.2127025180887077,0.3447912610633156,-0.17512221304650355,1.1665076288666967,-0.06148029559266701,0.4481994586006217,2.0714733698385936,-0.2911692129463672,2.436706104734128,4.50404309487471,0.3447912610633156,-0.5003402500028168,2.745005746127423,0.5244829444562599,-0.03343454335768025,-0.5308810490428666,4.224818104379722,0.02222921008355008,0.5496741112974982,1.2774266291404368,1.5136414157872253,0.10467597056101892,1.2333342498208812,-0.17512221304650355,0.5244829444562599,0.13188385952514886,-0.350125356105606,-0.5003402500028168,0.0498499651371408,-0.005531837066441173,0.18589586847145548,-5.288752019977064,0.2127025180887077,0.5244829444562599,0.2127025180887077,-0.43976167580769304,0.5496741112974982,-0.14649000038336524,0.15895673427969537,0.0498499651371408,0.10467597056101892,0.31862879037972053,0.4225314103597223,2.9887072724789827,0.2923398612170866,-0.32056824010222307,0.5244829444562599,-0.08967050071108885,-0.5615918989070766,0.10467597056101892,-0.7814856320202566,1.3645361307346424,2.090348997439926,-0.4097204049195783,-0.06148029559266701,0.4481994586006217,1.0303037635203478,0.2127025180887077,-0.03343454335768025,-0.06148029559266701,-0.6235310490678561,0.8669105116207638,0.2127025180887077,-0.03343454335768025,0.5496741112974982,-0.08967050071108885,-0.005531837066441173,0.2659233011870234,0.13188385952514886,0.8431585826801586,-0.2911692129463672,-0.005531837066441173,-0.7177615370892623,0.0498499651371408,2.2206204495029636,0.7228043903765459,-0.2328390217993925,0.07733177575208161,0.3447912610633156,0.37082842982646413,0.2923398612170866
| 2,702
|
Protein localization
| 23
| 68
| 3.134642
| 0.001721
|
Q9BY49,Q99595,Q9NS69,P09601,Q8N4H5,Q13190,Q15067,P21796,Q9NX63,P06576,Q13011,O75874,Q9NR77,Q9BVV7,Q13505,O15254,O75431,Q15388,Q8NBU5,P40855,P50402,P46379,P50542
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
129,5,6,137,138,269,274,31,290,292,48,54,453,451,64,72,461,86,488,223,367,123,379
|
923,852,1450,72,729,926,1710,1131,1456,2249,461,2324,1008,889,54,966,1415,699,292,666,2079,137,765,1980,1098,2552,31,860,896,1463,1465,1466,223,123,367,379,1180,1833,2334,1149,1110,48,269,64,274,86,1190,546,2696,138,488,1743,1587,5,2169,451,129,607,453,6,290,1296,812,2023,2241,1490,493,884
|
0.15895673427969537,0.2127025180887077,-0.17512221304650355,2.2389705497371217,0.31862879037972053,0.15895673427969537,-0.32056824010222307,0.02222921008355008,-0.17512221304650355,-0.6861725882485472,0.5997077106006617,-0.7495318851344548,0.10467597056101892,0.18589586847145548,2.558767311500275,0.13188385952514886,-0.14649000038336524,0.3447912610633156,0.9141025725456303,0.37082842982646413,-0.5308810490428666,1.5762892971839588,0.2923398612170866,-0.4699677127277454,0.0498499651371408,-1.1115742979561345,3.281841750088034,0.2127025180887077,0.18589586847145548,-0.17512221304650355,-0.17512221304650355,-0.17512221304650355,1.1665076288666967,1.6586894203500797,0.747090864182487,0.7228043903765459,-0.005531837066441173,-0.37984219227896826,-0.7495318851344548,0.02222921008355008,0.0498499651371408,2.745005746127423,1.0072634916981495,2.3477474020211564,0.9841240598522195,2.0714733698385936,-0.005531837066441173,0.49917415125399284,-4.8821959377233615,1.5762892971839588,0.5747486913303033,-0.32056824010222307,-0.2328390217993925,5.198120334434664,-0.5924746168808616,0.6245521818790327,1.638208714171853,0.4481994586006217,0.6245521818790327,4.890473754334426,0.9375444335085626,-0.06148029559266701,0.2659233011870234,-0.4699677127277454,-0.654763070997487,-0.17512221304650355,0.5747486913303033,0.2127025180887077
| 2,702
|
Organelle inner membrane
| 57
| 205
| 3.131268
| 0.001741
|
Q8IXM6,Q99595,O75964,O43772,Q9BPX6,Q99720,Q9UDX5,P14406,Q9NX63,P00403,O75600,O95831,P06576,Q99623,P43304,Q13423,Q70HW3,O96000,O75880,Q9H2D1,Q03252,Q9Y2R0,Q567V2,Q13505,Q9BVV7,Q69YU5,Q6P4A7,O75844,P22830,Q9BYD6,Q9Y2U8,P62995,O75431,P23786,P56385,Q9Y5J7,O95674,Q9Y3B7,Q15070,Q14739,Q16891,Q14197,P52815,P18031,P13073,O95139,P20700,P56134,P50402,O60313,Q96NB2,Q9UBX3,P22695,Q8N983,Q9H2W6,Q6DKK2,O43676
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
263,5,256,10,139,14,148,22,290,35,291,39,292,436,42,177,49,172,296,184,428,56,63,64,451,204,75,74,81,469,353,465,461,88,347,493,341,492,224,359,485,483,357,479,477,474,499,369,367,363,511,516,122,384,251,126,127
|
2142,1708,852,1764,729,127,925,10,363,888,1361,730,461,2324,646,291,1458,889,74,296,1136,256,1091,2032,474,856,1415,1499,818,1931,2658,341,39,172,699,35,1048,292,2292,666,1267,1311,1876,1268,765,1980,1098,1816,477,22,1669,1270,479,1771,649,499,1717,2190,122,81,1053,88,621,896,1272,1719,2364,672,1317,1015,936,1466,1468,1469,796,42,1370,1615,2394,2331,367,1571,1017,357,2088,1572,369,347,2487,465,940,827,741,1728,1182,2398,861,1786,1471,428,1110,1111,568,177,64,483,359,224,908,2504,544,1998,485,1190,867,63,1382,2571,1118,204,126,713,75,1065,774,2001,49,504,714,1387,2465,263,384,2132,2235,1640,1162,1955,1338,2635,2665,954,2506,511,1247,5,436,14,139,781,1036,1443,2520,2010,1482,451,2409,846,2012,469,2103,2238,184,1915,251,2429,606,1294,1859,2636,607,608,2509,2280,1918,1295,757,961,290,1346,1807,1808,532,516,721,148,1297,919,812,576,2023,1545,56,2651,353,2286,492,1546,644,1490,493,884,1084,697,1971
|
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