term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steroid metabolic process
| 11
| 58
| 2.318042
| 0.020447
|
Q99538,Q9H4L5,Q9BQE5,Q8WTV0,P48449,P61916,Q13510,Q15392,P37268,O15118,Q16850
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,100,37,69,43,142,111,112,53,24,26
|
24,557,2032,664,648,2586,443,968,2079,1222,1713,2384,1051,669,860,2190,1504,1463,412,53,413,233,2039,43,1615,2086,1833,2297,142,2267,1229,901,111,2402,484,359,2050,112,2425,304,1846,804,26,746,1999,164,69,2674,1643,99,1644,37,2061,100,660,455,2065,2495
|
3.530739879481159,0.473746678395286,-0.5003402500028168,0.37082842982646413,0.39674143767950243,-1.2492972789568666,0.6245521818790327,0.13188385952514886,-0.5308810490428666,-0.03343454335768025,-0.32056824010222307,-0.8136248100970255,0.07733177575208161,0.37082842982646413,0.2127025180887077,-0.6235310490678561,-0.2039047156366997,-0.17512221304650355,0.673901466516914,2.6102209682067175,0.673901466516914,1.1214892721063172,-0.5003402500028168,2.827512784417395,-0.2619266677946719,-0.5308810490428666,-0.37984219227896826,-0.7177615370892623,1.5554884161976426,-0.6861725882485472,-0.03343454335768025,0.18589586847145548,1.7799433878907398,-0.8136248100970255,0.5747486913303033,0.7712686001756313,-0.5003402500028168,1.7599256653622593,-0.8459514851409792,0.890558218300318,-0.37984219227896826,0.2659233011870234,3.487680492801992,0.31862879037972053,-0.4699677127277454,1.4289490678170462,2.275479978158442,-2.1553332825055893,-0.2619266677946719,1.8789142803170127,-0.2619266677946719,2.9887072724789827,-0.5003402500028168,1.8789142803170127,0.39674143767950243,0.6245521818790327,-0.5003402500028168,-0.9440776667177786
| 2,702
|
Oxidoreductase
| 15
| 106
| 2.317707
| 0.020465
|
P30837,Q9BY49,P00403,O95831,O94788,O15260,O15254,P43304,P11310,Q15392,P14406,Q8N4Q0,Q16850,Q8N8N7,O43169
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
33,129,35,39,8,59,72,42,141,112,22,157,26,27,61
|
2142,2143,1708,72,59,61,2029,925,1929,1361,730,296,2456,2032,8,856,1415,39,930,2188,1219,700,286,35,792,1932,375,2292,620,1268,141,1222,2597,1223,793,22,2294,2384,1669,649,1717,2036,2150,934,1272,2260,1877,1273,1013,33,1719,2363,2153,1464,936,1986,1939,2328,42,2556,2681,1615,2196,1942,1017,2043,2087,2088,466,2302,654,742,177,484,359,2624,274,112,804,908,544,1998,26,2505,945,2001,2208,1794,157,27,658,2674,955,1644,349,129,350,606,2636,2109,2173,532,660,2493,721,1971
|
-0.5924746168808616,-0.5924746168808616,-0.32056824010222307,2.2389705497371217,2.419034532533944,2.365660090880429,-0.5003402500028168,0.15895673427969537,-0.43976167580769304,-0.1180065861783075,0.31862879037972053,0.890558218300318,-0.9111757607706441,-0.5003402500028168,4.492217400733412,0.2127025180887077,-0.14649000038336524,2.9408710467958437,0.15895673427969537,-0.6235310490678561,-0.03343454335768025,0.3447912610633156,0.9375444335085626,3.1141580717849924,0.2659233011870234,-0.43976167580769304,0.7228043903765459,-0.7177615370892623,0.4225314103597223,-0.06148029559266701,1.5554884161976426,-0.03343454335768025,-1.2842660323097124,-0.03343454335768025,0.2659233011870234,3.643834047397023,-0.7177615370892623,-0.8136248100970255,-0.2911692129463672,0.39674143767950243,-0.32056824010222307,-0.5003402500028168,-0.5924746168808616,0.15895673427969537,-0.06148029559266701,-0.6861725882485472,-0.4097204049195783,-0.06148029559266701,0.10467597056101892,3.160430985084966,-0.32056824010222307,-0.7814856320202566,-0.5924746168808616,-0.17512221304650355,0.15895673427969537,-0.4699677127277454,-0.43976167580769304,-0.7495318851344548,2.827512784417395,-1.1115742979561345,-2.5804238826626027,-0.2619266677946719,-0.6235310490678561,-0.43976167580769304,0.10467597056101892,-0.5003402500028168,-0.5308810490428666,-0.5308810490428666,0.5997077106006617,-0.7177615370892623,0.39674143767950243,0.31862879037972053,1.386093528320324,0.5747486913303033,0.7712686001756313,-1.4263717244472445,0.9841240598522195,1.7599256653622593,0.2659233011870234,0.18589586847145548,0.49917415125399284,-0.4699677127277454,3.487680492801992,-0.977175681919584,0.15895673427969537,-0.4699677127277454,-0.6235310490678561,-0.350125356105606,1.4714633126430223,3.385787138944637,0.39674143767950243,-2.1553332825055893,0.15895673427969537,-0.2619266677946719,0.7953385242734627,1.638208714171853,0.7953385242734627,0.4481994586006217,-1.5353706399979128,-0.5308810490428666,-0.5924746168808616,0.5244829444562599,0.39674143767950243,-0.9440776667177786,0.3447912610633156,-0.43976167580769304
| 2,702
|
Platyspondyly
| 6
| 30
| 2.317673
| 0.020467
|
P16278,Q32P28,O95831,P48735,O75874,P00813
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,68,39,17,54,93
|
2143,2475,136,2290,54,39,93,582,701,128,2257,2035,2081,1564,17,1016,741,2399,654,359,1061,68,545,713,982,1903,509,276,2213,1545
|
-0.5924746168808616,-0.9440776667177786,1.5762892971839588,-0.7177615370892623,2.558767311500275,2.9408710467958437,1.9760700997311131,0.4481994586006217,0.3447912610633156,1.638208714171853,-0.6861725882485472,-0.5003402500028168,-0.5308810490428666,-0.2328390217993925,4.123983608212495,0.10467597056101892,0.31862879037972053,-0.8136248100970255,0.39674143767950243,0.7712686001756313,0.07733177575208161,2.293640144931326,0.49917415125399284,0.3447912610633156,0.13188385952514886,-0.4097204049195783,0.5496741112974982,0.9841240598522195,-0.6235310490678561,-0.2039047156366997
| 2,702
|
Abnormality of head blood vessel
| 6
| 23
| 2.314153
| 0.020659
|
P16278,P21964,P10619,P17900,Q13510,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,34,163,70,111,57
|
1353,536,2648,168,57,1096,163,1714,128,70,1716,34,1937,2500,1834,1624,111,543,2236,872,880,661,1864
|
-0.1180065861783075,0.49917415125399284,-1.6840786597335329,1.4075642865122227,2.436706104734128,0.0498499651371408,1.4289490678170462,-0.32056824010222307,1.638208714171853,2.2572569188414064,-0.32056824010222307,3.1296283127460667,-0.43976167580769304,-0.977175681919584,-0.37984219227896826,-0.2619266677946719,1.7799433878907398,0.49917415125399284,-0.654763070997487,0.2127025180887077,0.2127025180887077,0.39674143767950243,-0.37984219227896826
| 2,702
|
Decreased plasma carnitine
| 7
| 13
| 2.306216
| 0.021099
|
Q16836,O43772,Q9H845,P11310,O75880,P09622,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
503,10,606,141,296,620,88
|
10,616,296,620,141,88,1465,1468,1615,1149,503,1153,606
|
4.396604319498196,0.4225314103597223,0.890558218300318,0.4225314103597223,1.5554884161976426,2.0525300254302943,-0.17512221304650355,-0.17512221304650355,-0.2619266677946719,0.02222921008355008,0.5496741112974982,0.02222921008355008,0.4481994586006217
| 2,702
|
Intermediate filament protein, conserved site [IPR018039]
| 7
| 8
| 2.30433
| 0.021204
|
P02545,P07196,P48681,P08670,P07197,Q03252,Q16352
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
374,315,356,202,475,428,281
|
374,315,475,202,499,356,428,281
|
0.7228043903765459,0.8431585826801586,0.5747486913303033,1.255425828169697,0.5496741112974982,0.7712686001756313,0.6492831048866388,0.9608846498386505
| 2,702
|
Intermediate filament, rod domain [IPR039008]
| 7
| 8
| 2.30433
| 0.021204
|
P02545,P07196,P48681,P08670,P07197,Q03252,Q16352
|
Sequence
|
InterPro Domain
|
interpro_domain
|
374,315,356,202,475,428,281
|
374,315,475,202,499,356,428,281
|
0.7228043903765459,0.8431585826801586,0.5747486913303033,1.255425828169697,0.5496741112974982,0.7712686001756313,0.6492831048866388,0.9608846498386505
| 2,702
|
calmodulin-related
| 6
| 9
| 2.304
| 0.021223
|
Q9BPX6,Q15293,O43852,Q14257,P80303,Q02818
|
Functions
|
Panther Protein class
|
panther_protein_class
|
139,82,179,116,118,244
|
179,2118,623,397,118,244,116,82,139
|
1.3645361307346424,-0.5615918989070766,0.4225314103597223,0.698408241052304,1.7196623603455143,1.0760900505966375,1.7398321727024608,2.183727349455117,1.5762892971839588
| 2,702
|
Hydrogen ion transport
| 8
| 19
| 2.292465
| 0.021879
|
P61421,O75964,P06576,Q9Y487,Q15904,P56134,Q9Y5K8,P56385
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
414,256,292,78,234,369,388,347
|
1136,256,292,823,1772,621,896,1015,898,1780,1370,369,347,414,234,529,1348,78,388
|
0.02222921008355008,1.0303037635203478,0.9141025725456303,0.23937792178355133,-0.350125356105606,0.4225314103597223,0.18589586847145548,0.10467597056101892,0.18589586847145548,-0.350125356105606,-0.1180065861783075,0.747090864182487,0.7953385242734627,0.673901466516914,1.1214892721063172,0.5244829444562599,-0.08967050071108885,2.2206204495029636,0.7228043903765459
| 2,702
|
Ascites
| 10
| 23
| 2.280694
| 0.022567
|
Q14739,P14314,P38571,P61916,Q13510,Q14108,P16930,O15118,Q01844,Q9NSD9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
359,444,233,142,111,19,364,24,382,327
|
24,2288,2613,1176,443,701,1010,444,364,233,1833,142,2301,940,1059,382,655,111,19,359,2403,327,1598
|
3.530739879481159,-0.7177615370892623,-1.3548673355819485,-0.005531837066441173,0.6245521818790327,0.3447912610633156,0.10467597056101892,0.6245521818790327,0.747090864182487,1.1214892721063172,-0.37984219227896826,1.5554884161976426,-0.7177615370892623,0.15895673427969537,0.07733177575208161,0.7228043903765459,0.39674143767950243,1.7799433878907398,4.111237733873485,0.7712686001756313,-0.8136248100970255,0.8431585826801586,-0.2328390217993925
| 2,702
|
Neuromuscular process
| 10
| 25
| 2.278603
| 0.022691
|
P17900,P04062,P07196,O14773,Q8IZL8,O75844,Q8N0X7,Q6Y7W6,P10253,P50542
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
70,443,315,201,170,74,333,110,463,379
|
201,816,1457,74,443,315,1096,463,1269,70,1563,1612,2518,2085,379,2086,770,944,1287,110,505,170,333,956,843
|
1.255425828169697,0.23937792178355133,-0.17512221304650355,2.2206204495029636,0.6245521818790327,0.8431585826801586,0.0498499651371408,0.5997077106006617,-0.06148029559266701,2.2572569188414064,-0.2328390217993925,-0.2619266677946719,-1.0104720506565676,-0.5308810490428666,0.7228043903765459,-0.5308810490428666,0.2923398612170866,0.15895673427969537,-0.06148029559266701,1.7998858840313976,0.5496741112974982,1.4075642865122227,0.8193015508006276,0.15895673427969537,0.23937792178355133
| 2,702
|
Abnormal circulating fatty acid anion concentration
| 7
| 15
| 2.276862
| 0.022794
|
Q16836,O43772,Q9H845,P11310,O75880,P09622,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
503,10,606,141,296,620,88
|
10,616,296,620,141,1558,88,1465,1468,1615,1572,1149,503,1153,606
|
4.396604319498196,0.4225314103597223,0.890558218300318,0.4225314103597223,1.5554884161976426,-0.2328390217993925,2.0525300254302943,-0.17512221304650355,-0.17512221304650355,-0.2619266677946719,-0.2328390217993925,0.02222921008355008,0.5496741112974982,0.02222921008355008,0.4481994586006217
| 2,702
|
Abdominal pain
| 11
| 68
| 2.273593
| 0.02299
|
O15460,Q14566,Q9NZ08,Q13423,P42892,Q70HW3,Q8NFH4,Q14108,P23786,P06280,P35637
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
89,36,135,177,80,49,212,19,88,149,155
|
1175,89,887,2648,443,1266,149,857,1096,1666,1010,1097,1222,218,444,1716,1717,1052,88,1719,1367,1937,155,936,1419,2460,2328,80,1056,1369,2194,2395,1782,705,2486,2335,1624,427,382,1471,280,655,1322,177,19,36,632,680,543,2403,2404,1478,524,49,506,507,212,1242,1069,1031,1341,1700,135,2316,611,661,1864,1407
|
-0.005531837066441173,2.0335184987881214,0.18589586847145548,-1.6840786597335329,0.6245521818790327,-0.06148029559266701,1.4925940643576996,0.2127025180887077,0.0498499651371408,-0.2911692129463672,0.10467597056101892,0.0498499651371408,-0.03343454335768025,1.1888758808001145,0.6245521818790327,-0.32056824010222307,-0.32056824010222307,0.07733177575208161,2.0525300254302943,-0.32056824010222307,-0.1180065861783075,-0.43976167580769304,1.4714633126430223,0.15895673427969537,-0.14649000038336524,-0.9111757607706441,-0.7495318851344548,2.202206192643275,0.07733177575208161,-0.1180065861783075,-0.6235310490678561,-0.8136248100970255,-0.350125356105606,0.3447912610633156,-0.9440776667177786,-0.7495318851344548,-0.2619266677946719,0.6492831048866388,0.7228043903765459,-0.17512221304650355,0.9608846498386505,0.39674143767950243,-0.08967050071108885,1.386093528320324,4.111237733873485,3.0045553572629977,0.4225314103597223,0.37082842982646413,0.49917415125399284,-0.8136248100970255,-0.8136248100970255,-0.17512221304650355,0.5244829444562599,2.745005746127423,0.5496741112974982,0.5496741112974982,1.2333342498208812,-0.03343454335768025,0.07733177575208161,0.10467597056101892,-0.08967050071108885,-0.2911692129463672,1.5970092420957023,-0.7177615370892623,0.4481994586006217,0.39674143767950243,-0.37984219227896826,-0.1180065861783075
| 2,702
|
Abnormal circulating lipid concentration
| 29
| 69
| 2.271889
| 0.023093
|
P02545,Q16836,Q9UIG0,Q9UBM7,O43772,P61916,P11310,P06280,Q8WXH0,P28070,Q15056,O75880,Q03252,P37268,P07602,Q9H845,O75844,P22830,O75431,P23786,P40855,Q14739,P38571,Q15904,Q15392,P50402,P09622,O75648,P50542
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
374,503,661,660,10,142,141,149,547,159,543,296,428,53,57,606,74,81,461,88,223,359,233,234,112,367,620,616,379
|
1353,887,2648,10,1456,461,616,74,296,648,374,149,2078,57,620,141,1558,81,88,159,2528,1937,2529,1465,53,233,223,1468,1569,2499,1941,1615,367,379,2332,1833,2156,1572,705,142,1624,2399,428,1149,828,1889,2093,359,543,112,1846,804,234,503,1153,1901,547,1198,1443,2620,606,961,880,660,661,812,2432,1864,1598
|
-0.1180065861783075,0.18589586847145548,-1.6840786597335329,4.396604319498196,-0.17512221304650355,0.5997077106006617,0.4225314103597223,2.2206204495029636,0.890558218300318,0.39674143767950243,0.7228043903765459,1.4925940643576996,-0.5308810490428666,2.436706104734128,0.4225314103597223,1.5554884161976426,-0.2328390217993925,2.183727349455117,2.0525300254302943,1.4502485272895491,-1.0439690553345753,-0.43976167580769304,-1.0439690553345753,-0.17512221304650355,2.6102209682067175,1.1214892721063172,1.1665076288666967,-0.17512221304650355,-0.2328390217993925,-0.977175681919584,-0.43976167580769304,-0.2619266677946719,0.747090864182487,0.7228043903765459,-0.7495318851344548,-0.37984219227896826,-0.5924746168808616,-0.2328390217993925,0.3447912610633156,1.5554884161976426,-0.2619266677946719,-0.8136248100970255,0.6492831048866388,0.02222921008355008,0.23937792178355133,-0.4097204049195783,-0.5308810490428666,0.7712686001756313,0.49917415125399284,1.7599256653622593,-0.37984219227896826,0.2659233011870234,1.1214892721063172,0.5496741112974982,0.02222921008355008,-0.4097204049195783,0.49917415125399284,-0.005531837066441173,-0.14649000038336524,-1.3905052682383434,0.4481994586006217,0.15895673427969537,0.2127025180887077,0.39674143767950243,0.39674143767950243,0.2659233011870234,-0.8459514851409792,-0.37984219227896826,-0.2328390217993925
| 2,702
|
Neuron death
| 15
| 63
| 2.262846
| 0.023645
|
Q99538,O95831,P07196,P09601,P48681,Q01105,Q14790,Q99720,Q15392,O14786,Q9UMX5,Q9UL15,P50897,Q9NR28,O14578
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,39,315,137,356,238,303,14,112,242,20,154,52,253,338
|
338,242,1304,1455,2575,967,39,443,792,1932,1266,1310,2458,315,1416,137,2357,1222,1716,1776,1367,937,1056,366,356,2194,2085,2394,52,2086,565,2546,2046,1617,1726,2502,2443,238,1838,1283,2303,803,1428,631,303,1025,831,112,548,809,913,956,2593,99,14,1487,785,253,1923,154,20,1298,1447
|
0.7953385242734627,1.0760900505966375,-0.08967050071108885,-0.17512221304650355,-1.2145462814230732,0.13188385952514886,2.9408710467958437,0.6245521818790327,0.2659233011870234,-0.43976167580769304,-0.06148029559266701,-0.08967050071108885,-0.9111757607706441,0.8431585826801586,-0.14649000038336524,1.5762892971839588,-0.7814856320202566,-0.03343454335768025,-0.32056824010222307,-0.350125356105606,-0.1180065861783075,0.15895673427969537,0.07733177575208161,0.747090864182487,0.7712686001756313,-0.6235310490678561,-0.5308810490428666,-0.8136248100970255,2.678047917700652,-0.5308810490428666,0.473746678395286,-1.0776690173461208,-0.5003402500028168,-0.2619266677946719,-0.32056824010222307,-0.977175681919584,-0.8784677570852006,1.0988376535312658,-0.37984219227896826,-0.06148029559266701,-0.7177615370892623,0.2659233011870234,-0.14649000038336524,0.4225314103597223,0.890558218300318,0.10467597056101892,0.23937792178355133,1.7599256653622593,0.49917415125399284,0.2659233011870234,0.18589586847145548,0.15895673427969537,-1.2492972789568666,1.8789142803170127,4.199796153109882,-0.17512221304650355,0.2923398612170866,1.0532456836169948,-0.4097204049195783,1.4925940643576996,3.7407899746586426,-0.06148029559266701,-0.14649000038336524
| 2,702
|
Arteriosclerosis
| 7
| 13
| 2.256732
| 0.024025
|
P16278,P02545,P38571,P61916,O75844,Q13510,O15118
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,374,233,142,74,111,24
|
24,1414,74,374,128,1769,2385,2119,413,233,142,111,635
|
3.530739879481159,-0.14649000038336524,2.2206204495029636,0.7228043903765459,1.638208714171853,-0.350125356105606,-0.8136248100970255,-0.5615918989070766,0.673901466516914,1.1214892721063172,1.5554884161976426,1.7799433878907398,0.4225314103597223
| 2,702
|
Gland development
| 12
| 66
| 2.254723
| 0.024151
|
Q13505,Q15418,P00403,Q96JB5,Q16706,O94788,P09601,P11310,O75844,P11717,P07602,P00813
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,2,35,200,132,8,137,141,74,120,57,93
|
1599,338,1763,242,1552,1457,74,8,35,93,583,792,2189,57,1666,137,2578,141,120,1979,444,794,2515,587,1716,1504,1607,1418,2388,2191,412,1776,1464,1367,2588,2194,2394,1277,2546,2335,541,2488,1683,973,802,64,1788,570,1431,2,304,2464,132,1740,2101,2236,200,436,2169,640,604,1345,514,880,611,2511
|
-0.2619266677946719,0.7953385242734627,-0.350125356105606,1.0760900505966375,-0.2328390217993925,-0.17512221304650355,2.2206204495029636,4.492217400733412,3.1141580717849924,1.9760700997311131,0.4481994586006217,0.2659233011870234,-0.6235310490678561,2.436706104734128,-0.2911692129463672,1.5762892971839588,-1.2145462814230732,1.5554884161976426,1.6994156728204817,-0.4699677127277454,0.6245521818790327,0.2659233011870234,-1.0104720506565676,0.4481994586006217,-0.32056824010222307,-0.2039047156366997,-0.2619266677946719,-0.14649000038336524,-0.8136248100970255,-0.6235310490678561,0.673901466516914,-0.350125356105606,-0.17512221304650355,-0.1180065861783075,-1.2492972789568666,-0.6235310490678561,-0.8136248100970255,-0.06148029559266701,-1.0776690173461208,-0.7495318851344548,0.49917415125399284,-0.9440776667177786,-0.2911692129463672,0.13188385952514886,0.2659233011870234,2.3477474020211564,-0.350125356105606,0.473746678395286,-0.14649000038336524,5.468469224387756,0.890558218300318,-0.9111757607706441,1.5970092420957023,-0.32056824010222307,-0.5308810490428666,-0.654763070997487,1.2774266291404368,0.6492831048866388,-0.5924746168808616,0.4225314103597223,0.4481994586006217,-0.08967050071108885,0.5496741112974982,0.2127025180887077,0.4481994586006217,-0.977175681919584
| 2,702
|
Abnormality of salivation
| 11
| 39
| 2.252378
| 0.024298
|
Q15165,Q14739,P51812,Q8N0X7,P15586,Q03252,Q01082,Q9BVA1,P35637,Q92804,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
262,359,11,333,174,428,427,220,155,250,453
|
1353,1601,1264,1177,891,1667,174,1315,672,155,2329,1140,796,1369,1143,738,2086,1990,11,1882,799,427,428,482,1021,944,359,262,831,333,991,250,1587,2005,1339,1911,220,689,453
|
-0.1180065861783075,-0.2619266677946719,-0.06148029559266701,-0.005531837066441173,0.18589586847145548,-0.2911692129463672,1.386093528320324,-0.08967050071108885,0.37082842982646413,1.4714633126430223,-0.7495318851344548,0.02222921008355008,0.2659233011870234,-0.1180065861783075,0.02222921008355008,0.31862879037972053,-0.5308810490428666,-0.4699677127277454,4.3359171716292355,-0.4097204049195783,0.2659233011870234,0.6492831048866388,0.6492831048866388,0.5747486913303033,0.10467597056101892,0.15895673427969537,0.7712686001756313,1.0303037635203478,0.23937792178355133,0.8193015508006276,0.13188385952514886,1.0532456836169948,-0.2328390217993925,-0.4699677127277454,-0.08967050071108885,-0.4097204049195783,1.1888758808001145,0.37082842982646413,0.6245521818790327
| 2,702
|
Limb ataxia
| 9
| 22
| 2.250989
| 0.024386
|
Q8IV08,P07196,O14773,Q9BUK6,Q14108,P41440,Q12768,O15020,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,315,201,108,19,115,308,285,453
|
1974,2475,201,285,443,2383,315,2189,2253,1719,1224,115,1110,308,19,4,1911,108,453,1041,2495,644
|
-0.4699677127277454,-0.9440776667177786,1.255425828169697,0.9375444335085626,0.6245521818790327,-0.8136248100970255,0.8431585826801586,-0.6235310490678561,-0.6861725882485472,-0.32056824010222307,-0.03343454335768025,1.7398321727024608,0.0498499651371408,0.8669105116207638,4.111237733873485,5.2288928568634425,-0.4097204049195783,1.8197536917866635,0.6245521818790327,0.10467597056101892,-0.9440776667177786,0.4225314103597223
| 2,702
|
EF-hand domain pair [IPR011992]
| 9
| 40
| 2.247739
| 0.024593
|
Q9UBV8,Q9BPX6,P43304,Q15293,O43852,Q14257,P80303,Q9NWM8,Q9Y680
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
77,139,42,82,179,116,118,153,221
|
887,179,2353,889,818,2189,1050,2653,444,1312,2118,623,1568,42,767,1373,397,118,244,2602,903,116,2160,82,772,713,1290,989,1692,990,637,509,139,1079,153,77,812,724,1810,221
|
0.18589586847145548,1.3645361307346424,-0.7814856320202566,0.18589586847145548,0.23937792178355133,-0.6235310490678561,0.07733177575208161,-1.7218791207703874,0.6245521818790327,-0.08967050071108885,-0.5615918989070766,0.4225314103597223,-0.2328390217993925,2.827512784417395,0.2923398612170866,-0.1180065861783075,0.698408241052304,1.7196623603455143,1.0760900505966375,-1.2842660323097124,0.18589586847145548,1.7398321727024608,-0.5924746168808616,2.183727349455117,0.2923398612170866,0.3447912610633156,-0.06148029559266701,0.13188385952514886,-0.2911692129463672,0.13188385952514886,0.4225314103597223,0.5496741112974982,1.5762892971839588,0.07733177575208161,1.4925940643576996,2.2206204495029636,0.2659233011870234,0.3447912610633156,-0.350125356105606,1.1888758808001145
| 2,702
|
Negative regulation of mrna processing
| 10
| 22
| 2.247242
| 0.024625
|
P50750,P38159,P61978,Q13242,Q13247,Q08170,Q5VTR2,P22626,O75494,P98175
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
564,176,301,370,249,593,523,345,558,416
|
1866,1352,1089,558,1715,345,971,1363,176,564,301,416,974,593,1577,370,249,1474,633,523,1331,1193
|
-0.4097204049195783,-0.1180065861783075,0.0498499651371408,0.473746678395286,-0.32056824010222307,0.7953385242734627,0.13188385952514886,-0.1180065861783075,1.386093528320324,0.473746678395286,0.890558218300318,0.673901466516914,0.13188385952514886,0.4481994586006217,-0.2328390217993925,0.747090864182487,1.0532456836169948,-0.17512221304650355,0.4225314103597223,0.5244829444562599,-0.08967050071108885,-0.005531837066441173
| 2,702
|
Abnormal systemic blood pressure
| 19
| 72
| 2.227433
| 0.025918
|
P02545,O43772,P06280,Q9UDY2,P49366,P21964,P00403,P35611,Q13423,P07602,Q9NSD9,P04062,O75844,P42892,Q9Y2U8,P38571,Q6Y7W6,Q08AM6,P20700
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
374,10,149,552,288,34,35,539,177,57,327,443,74,80,353,233,110,482,499
|
1351,926,887,2648,10,2144,1414,74,2477,35,374,443,1266,149,57,1096,1666,1010,1051,1012,499,1716,1717,34,1504,671,1463,1719,2119,1823,1937,539,1465,936,1419,233,2328,2517,80,1369,288,1834,1624,1471,1838,482,1110,655,1322,177,1788,944,1735,865,543,2403,110,2236,872,956,2010,1647,879,1650,327,880,552,661,353,1864,1407,1598
|
-0.1180065861783075,0.15895673427969537,0.18589586847145548,-1.6840786597335329,4.396604319498196,-0.5924746168808616,-0.14649000038336524,2.2206204495029636,-0.9440776667177786,3.1141580717849924,0.7228043903765459,0.6245521818790327,-0.06148029559266701,1.4925940643576996,2.436706104734128,0.0498499651371408,-0.2911692129463672,0.10467597056101892,0.07733177575208161,0.10467597056101892,0.5496741112974982,-0.32056824010222307,-0.32056824010222307,3.1296283127460667,-0.2039047156366997,0.37082842982646413,-0.17512221304650355,-0.32056824010222307,-0.5615918989070766,-0.37984219227896826,-0.43976167580769304,0.49917415125399284,-0.17512221304650355,0.15895673427969537,-0.14649000038336524,1.1214892721063172,-0.7495318851344548,-1.0104720506565676,2.202206192643275,-0.1180065861783075,0.9375444335085626,-0.37984219227896826,-0.2619266677946719,-0.17512221304650355,-0.37984219227896826,0.5747486913303033,0.0498499651371408,0.39674143767950243,-0.08967050071108885,1.386093528320324,-0.350125356105606,0.15895673427969537,-0.32056824010222307,0.2127025180887077,0.49917415125399284,-0.8136248100970255,1.7998858840313976,-0.654763070997487,0.2127025180887077,0.15895673427969537,-0.4699677127277454,-0.2619266677946719,0.2127025180887077,-0.2619266677946719,0.8431585826801586,0.2127025180887077,0.49917415125399284,0.39674143767950243,0.7953385242734627,-0.37984219227896826,-0.1180065861783075,-0.2328390217993925
| 2,702
|
Secretory granule membrane
| 12
| 62
| 2.222069
| 0.026279
|
P42785,Q07065,P30519,O00264,Q96JJ7,O95721,O15439,P11279,Q9Y5K8,P11717,P07602,O15260
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,320,3,255,307,104,267,236,388,120,57,59
|
1925,255,2183,59,267,1661,1496,2144,1457,1555,104,57,463,376,236,120,586,895,3,2118,1054,766,1179,0,1722,1421,2394,1831,1422,2044,2157,1425,2123,2203,941,1107,320,2128,902,1886,1628,1629,743,596,1288,2095,1999,2572,637,1796,548,529,752,307,2210,878,1038,1701,880,1296,388,1216
|
-0.43976167580769304,1.0303037635203478,-0.6235310490678561,2.419034532533944,1.0072634916981495,-0.2911692129463672,-0.2039047156366997,-0.5924746168808616,-0.17512221304650355,-0.2328390217993925,1.8395473434978173,2.436706104734128,0.5997077106006617,0.7228043903765459,1.0988376535312658,1.6994156728204817,0.4481994586006217,0.18589586847145548,5.249303056100748,-0.5615918989070766,0.07733177575208161,0.2923398612170866,-0.005531837066441173,6.217718739388483,-0.32056824010222307,-0.14649000038336524,-0.8136248100970255,-0.37984219227896826,-0.14649000038336524,-0.5003402500028168,-0.5924746168808616,-0.14649000038336524,-0.5615918989070766,-0.6235310490678561,0.15895673427969537,0.0498499651371408,0.8431585826801586,-0.5615918989070766,0.18589586847145548,-0.4097204049195783,-0.2619266677946719,-0.2619266677946719,0.31862879037972053,0.4481994586006217,-0.06148029559266701,-0.5308810490428666,-0.4699677127277454,-1.1800104648843361,0.4225314103597223,-0.350125356105606,0.49917415125399284,0.5244829444562599,0.31862879037972053,0.890558218300318,-0.6235310490678561,0.2127025180887077,0.10467597056101892,-0.2911692129463672,0.2127025180887077,-0.06148029559266701,0.7228043903765459,-0.005531837066441173
| 2,702
|
Bilateral sensorineural hearing impairment
| 8
| 19
| 2.211694
| 0.026988
|
P00403,P38159,Q15067,Q01082,Q9NSE4,Q13217,P07602,P35637
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,176,274,427,87,348,57,155
|
926,35,57,1769,2385,2082,155,176,2156,1882,427,1021,348,274,1386,505,87,880,1704
|
0.15895673427969537,3.1141580717849924,2.436706104734128,-0.350125356105606,-0.8136248100970255,-0.5308810490428666,1.4714633126430223,1.386093528320324,-0.5924746168808616,-0.4097204049195783,0.6492831048866388,0.10467597056101892,0.7953385242734627,0.9841240598522195,-0.1180065861783075,0.5496741112974982,2.0714733698385936,0.2127025180887077,-0.2911692129463672
| 2,702
|
Predicted secreted proteins
| 16
| 47
| 2.204414
| 0.027495
|
Q15165,Q9BTY2,Q9NZ08,O00584,O60568,Q8WUJ1,P61916,Q08380,O14786,P14174,Q9UMX5,Q02818,P80303,P02786,Q9HB40,P43490
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
262,230,135,103,136,13,142,109,242,218,20,244,118,343,29,287
|
103,242,136,1217,518,647,1664,343,583,2458,560,2293,2562,218,2552,2035,670,2670,287,565,2368,740,142,2566,118,2662,244,974,109,630,975,2591,262,1585,1637,13,2166,1071,1856,230,1482,2013,29,135,372,20,1864
|
1.8395473434978173,1.0760900505966375,1.5762892971839588,-0.03343454335768025,0.5244829444562599,0.39674143767950243,-0.2911692129463672,0.7953385242734627,0.4481994586006217,-0.9111757607706441,0.473746678395286,-0.7177615370892623,-1.1456872992127736,1.1888758808001145,-1.1115742979561345,-0.5003402500028168,0.37082842982646413,-2.0740082524478405,0.9375444335085626,0.473746678395286,-0.7814856320202566,0.31862879037972053,1.5554884161976426,-1.1456872992127736,1.7196623603455143,-1.8756727477583501,1.0760900505966375,0.13188385952514886,1.7998858840313976,0.4225314103597223,0.13188385952514886,-1.2492972789568666,1.0303037635203478,-0.2328390217993925,-0.2619266677946719,4.212322514130888,-0.5924746168808616,0.07733177575208161,-0.37984219227896826,1.1440456767678313,-0.17512221304650355,-0.4699677127277454,3.341494967883903,1.5970092420957023,0.747090864182487,3.7407899746586426,-0.37984219227896826
| 2,702
|
Abnormality of adrenal morphology
| 6
| 22
| 2.201454
| 0.027704
|
P38571,O75844,P48735,O75874,Q8WWQ0,Q12768
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
233,74,17,54,119,308
|
74,54,374,1266,1010,2597,1051,1012,823,1716,1717,1719,1419,233,2328,17,1471,2268,308,1846,119,1344
|
2.2206204495029636,2.558767311500275,0.7228043903765459,-0.06148029559266701,0.10467597056101892,-1.2842660323097124,0.07733177575208161,0.10467597056101892,0.23937792178355133,-0.32056824010222307,-0.32056824010222307,-0.32056824010222307,-0.14649000038336524,1.1214892721063172,-0.7495318851344548,4.123983608212495,-0.17512221304650355,-0.6861725882485472,0.8669105116207638,-0.37984219227896826,1.7196623603455143,-0.08967050071108885
| 2,702
|
Abnormal muscle fiber morphology
| 19
| 57
| 2.196287
| 0.028071
|
Q9BPX6,Q99720,P35637,P00403,O95831,Q86U42,P61978,Q70HW3,P06753,Q9H2D1,P07196,P51114,O14979,P23786,P22626,Q9BUK6,P50402,O60313,O43676
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
139,14,155,35,39,305,301,49,297,184,315,203,330,88,345,108,367,363,127
|
1708,330,127,1872,363,2353,616,39,699,35,374,2577,297,315,2513,891,1980,2415,345,88,1719,1985,155,1826,796,2394,367,900,203,2485,1882,301,654,2630,2093,1947,2305,1894,1382,49,1691,505,305,2101,547,14,139,844,1443,108,184,2612,2023,2219,644,1598,2595
|
-0.32056824010222307,0.8193015508006276,1.638208714171853,-0.4097204049195783,0.747090864182487,-0.7814856320202566,0.4225314103597223,2.9408710467958437,0.3447912610633156,3.1141580717849924,0.7228043903765459,-1.2145462814230732,0.890558218300318,0.8431585826801586,-1.0104720506565676,0.18589586847145548,-0.4699677127277454,-0.8459514851409792,0.7953385242734627,2.0525300254302943,-0.32056824010222307,-0.4699677127277454,1.4714633126430223,-0.37984219227896826,0.2659233011870234,-0.8136248100970255,0.747090864182487,0.18589586847145548,1.255425828169697,-0.9440776667177786,-0.4097204049195783,0.890558218300318,0.39674143767950243,-1.4624695189023518,-0.5308810490428666,-0.43976167580769304,-0.7177615370892623,-0.4097204049195783,-0.1180065861783075,2.745005746127423,-0.2911692129463672,0.5496741112974982,0.890558218300318,-0.5308810490428666,0.49917415125399284,4.199796153109882,1.5762892971839588,0.23937792178355133,-0.14649000038336524,1.8197536917866635,1.3645361307346424,-1.3194551620520436,-0.4699677127277454,-0.6235310490678561,0.4225314103597223,-0.2328390217993925,-1.2492972789568666
| 2,702
|
Neurotransmitter receptors and postsynaptic signal transmission
| 8
| 35
| 2.193921
| 0.028241
|
Q15418,P53680,P51812,P52292,P04350,Q9BVA1,P68371,Q13885
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,318,11,300,210,220,124,190
|
1175,1555,1711,210,2568,315,732,1010,1011,1012,2388,2191,2264,1103,11,300,318,798,2203,1726,653,124,2445,190,1733,501,1287,2,2308,1852,603,220,1542,1704,1761
|
-0.005531837066441173,-0.2328390217993925,-0.32056824010222307,1.2333342498208812,-1.1800104648843361,0.8431585826801586,0.31862879037972053,0.10467597056101892,0.10467597056101892,0.10467597056101892,-0.8136248100970255,-0.6235310490678561,-0.6861725882485472,0.0498499651371408,4.3359171716292355,0.890558218300318,0.8431585826801586,0.2659233011870234,-0.6235310490678561,-0.32056824010222307,0.39674143767950243,1.6586894203500797,-0.8784677570852006,1.3428914236840213,-0.32056824010222307,0.5496741112974982,-0.06148029559266701,5.468469224387756,-0.7177615370892623,-0.37984219227896826,0.4481994586006217,1.1888758808001145,-0.2039047156366997,-0.2911692129463672,-0.32056824010222307
| 2,702
|
Proton transporting two sector atpase complex proton transporting domain
| 6
| 9
| 2.19245
| 0.028347
|
P61421,O75964,Q9Y487,Q93050,P56134,P56385
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
414,256,78,529,369,347
|
1136,256,621,1370,369,347,414,529,78
|
0.02222921008355008,1.0303037635203478,0.4225314103597223,-0.1180065861783075,0.747090864182487,0.7953385242734627,0.673901466516914,0.5244829444562599,2.2206204495029636
| 2,702
|
Abnormality of the peripheral nervous system
| 10
| 84
| 2.192259
| 0.028361
|
P21964,O95831,O95721,Q99720,Q6Y7W6,P42892,Q8N2K0,P41440,P07602,Q9NQZ5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,39,104,14,110,80,113,115,57,60
|
1353,727,2074,926,1263,1872,363,2144,2477,104,39,374,443,2640,149,315,57,1096,2149,2385,499,34,2364,1224,1565,2599,1826,115,80,796,1369,2499,2085,900,1422,2086,1833,1834,1882,2370,466,654,1838,1110,1886,829,1947,1324,274,830,1234,110,2572,505,113,1120,1159,1743,2101,1198,2236,872,602,956,2593,1911,14,755,1204,60,453,1650,1208,1961,880,1212,1041,660,1405,850,1809,1598,1084,494
|
-0.1180065861783075,0.31862879037972053,-0.5308810490428666,0.15895673427969537,-0.06148029559266701,-0.4097204049195783,0.747090864182487,-0.5924746168808616,-0.9440776667177786,1.8395473434978173,2.9408710467958437,0.7228043903765459,0.6245521818790327,-1.6092322015717255,1.4925940643576996,0.8431585826801586,2.436706104734128,0.0498499651371408,-0.5924746168808616,-0.8136248100970255,0.5496741112974982,3.1296283127460667,-0.7814856320202566,-0.03343454335768025,-0.2328390217993925,-1.2842660323097124,-0.37984219227896826,1.7398321727024608,2.202206192643275,0.2659233011870234,-0.1180065861783075,-0.977175681919584,-0.5308810490428666,0.18589586847145548,-0.14649000038336524,-0.5308810490428666,-0.37984219227896826,-0.37984219227896826,-0.4097204049195783,-0.7814856320202566,0.5997077106006617,0.39674143767950243,-0.37984219227896826,0.0498499651371408,-0.4097204049195783,0.23937792178355133,-0.43976167580769304,-0.08967050071108885,0.9841240598522195,0.23937792178355133,-0.03343454335768025,1.7998858840313976,-1.1800104648843361,0.5496741112974982,1.7599256653622593,0.0498499651371408,0.02222921008355008,-0.32056824010222307,-0.5308810490428666,-0.005531837066441173,-0.654763070997487,0.2127025180887077,0.4481994586006217,0.15895673427969537,-1.2492972789568666,-0.4097204049195783,4.199796153109882,0.31862879037972053,-0.005531837066441173,2.3835119137294205,0.6245521818790327,-0.2619266677946719,-0.005531837066441173,-0.43976167580769304,0.2127025180887077,-0.005531837066441173,0.10467597056101892,0.39674143767950243,-0.1180065861783075,0.23937792178355133,-0.350125356105606,-0.2328390217993925,0.07733177575208161,0.5747486913303033
| 2,702
|
Negative regulation of mrna splicing via spliceosome
| 8
| 15
| 2.191488
| 0.028416
|
P38159,P61978,Q13242,P22626,Q08170,Q13247,O75494,P98175
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
176,301,370,345,593,249,558,416
|
1352,558,345,971,1363,176,301,416,974,593,1577,370,249,1474,633
|
-0.1180065861783075,0.473746678395286,0.7953385242734627,0.13188385952514886,-0.1180065861783075,1.386093528320324,0.890558218300318,0.673901466516914,0.13188385952514886,0.4481994586006217,-0.2328390217993925,0.747090864182487,1.0532456836169948,-0.17512221304650355,0.4225314103597223
| 2,702
|
Endopeptidase activity
| 14
| 59
| 2.191039
| 0.028449
|
P28070,P49721,Q99538,Q9NZ08,P28074,P22695,O14773,O75844,Q8TCT8,P42892,Q99436,Q86UV5,Q16740,Q96K76
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
159,67,99,135,38,122,201,74,144,80,284,183,25,90
|
201,1007,2324,74,2189,2114,2552,733,122,1936,159,622,38,1984,734,2670,1567,937,80,1613,2296,1988,67,2394,2645,2396,2419,800,769,1110,655,1113,2161,303,25,1581,546,1791,2052,183,144,717,548,1954,1199,1587,874,90,876,1247,284,99,780,2210,452,135,848,725,644
|
1.255425828169697,0.10467597056101892,-0.7495318851344548,2.2206204495029636,-0.6235310490678561,-0.5615918989070766,-1.1115742979561345,0.31862879037972053,1.6586894203500797,-0.43976167580769304,1.4502485272895491,0.4225314103597223,2.9568654023721628,-0.4699677127277454,0.31862879037972053,-2.0740082524478405,-0.2328390217993925,0.15895673427969537,2.202206192643275,-0.2619266677946719,-0.7177615370892623,-0.4699677127277454,2.293640144931326,-0.8136248100970255,-1.646530754259767,-0.8136248100970255,-0.8459514851409792,0.2659233011870234,0.2923398612170866,0.0498499651371408,0.39674143767950243,0.0498499651371408,-0.5924746168808616,0.890558218300318,3.502073656744272,-0.2328390217993925,0.49917415125399284,-0.350125356105606,-0.5003402500028168,1.3645361307346424,1.5346059932631821,0.3447912610633156,0.49917415125399284,-0.43976167580769304,-0.005531837066441173,-0.2328390217993925,0.2127025180887077,2.0335184987881214,0.2127025180887077,-0.03343454335768025,0.9608846498386505,1.8789142803170127,0.2923398612170866,-0.6235310490678561,0.6245521818790327,1.5970092420957023,0.23937792178355133,0.3447912610633156,0.4225314103597223
| 2,702
|
Glycosidase
| 6
| 18
| 2.189724
| 0.028544
|
P16278,P54802,Q16706,P06865,O60502,P06280
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
128,98,132,168,46,149
|
2475,886,46,443,582,149,168,1096,701,463,128,2529,98,592,829,1735,132,230
|
-0.9440776667177786,0.18589586847145548,2.7781653386568346,0.6245521818790327,0.4481994586006217,1.4925940643576996,1.4075642865122227,0.0498499651371408,0.3447912610633156,0.5997077106006617,1.638208714171853,-1.0439690553345753,1.8789142803170127,0.4481994586006217,0.23937792178355133,-0.32056824010222307,1.5970092420957023,1.1440456767678313
| 2,702
|
Serine protease
| 7
| 27
| 2.182781
| 0.029052
|
P42785,P10619,O14773,Q9H3G5,P61978,Q8N2K0,Q9HB40
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
0,163,201,44,301,113,29
|
1492,201,163,2114,1984,2670,1567,0,2296,1105,1227,2156,301,769,630,1522,2307,332,113,489,952,1200,44,29,1863,2064,472
|
-0.2039047156366997,1.255425828169697,1.4289490678170462,-0.5615918989070766,-0.4699677127277454,-2.0740082524478405,-0.2328390217993925,6.217718739388483,-0.7177615370892623,0.0498499651371408,-0.03343454335768025,-0.5924746168808616,0.890558218300318,0.2923398612170866,0.4225314103597223,-0.2039047156366997,-0.7177615370892623,0.8193015508006276,1.7599256653622593,0.5747486913303033,0.15895673427969537,-0.005531837066441173,2.827512784417395,3.341494967883903,-0.37984219227896826,-0.5003402500028168,0.5997077106006617
| 2,702
|
Toe walking
| 9
| 20
| 2.181245
| 0.029165
|
Q9Y6X9,P02545,O95831,Q99720,P06753,P50402,Q01082,P07602,P35637
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
494,374,39,14,297,367,427,57,155
|
926,39,374,297,57,155,1468,367,2088,1882,1572,427,2650,2093,1121,547,14,1443,880,494
|
0.15895673427969537,2.9408710467958437,0.7228043903765459,0.890558218300318,2.436706104734128,1.4714633126430223,-0.17512221304650355,0.747090864182487,-0.5308810490428666,-0.4097204049195783,-0.2328390217993925,0.6492831048866388,-1.6840786597335329,-0.5308810490428666,0.0498499651371408,0.49917415125399284,4.199796153109882,-0.14649000038336524,0.2127025180887077,0.5747486913303033
| 2,702
|
Flavin adenine dinucleotide binding
| 6
| 25
| 2.178478
| 0.02937
|
O95831,O15254,P11310,Q15392,Q15067,Q8NB78
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
39,72,141,112,274,55
|
1658,923,72,1133,39,2586,286,620,141,1223,1558,1051,934,1719,1615,484,274,112,908,2505,2001,55,1746,955,606
|
-0.2911692129463672,0.15895673427969537,2.2389705497371217,0.02222921008355008,2.9408710467958437,-1.2492972789568666,0.9375444335085626,0.4225314103597223,1.5554884161976426,-0.03343454335768025,-0.2328390217993925,0.07733177575208161,0.15895673427969537,-0.32056824010222307,-0.2619266677946719,0.5747486913303033,0.9841240598522195,1.7599256653622593,0.18589586847145548,-0.977175681919584,-0.4699677127277454,2.5415030973697146,-0.32056824010222307,0.15895673427969537,0.4481994586006217
| 2,702
|
Protein import
| 16
| 81
| 2.178131
| 0.029396
|
P02545,Q99595,Q9NS69,O95831,P50542,O15397,Q14978,Q15648,Q99623,P12270,P52292,Q15388,Q9BVL2,O14737,P55735,P40855
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
374,5,6,39,379,313,398,304,436,394,300,86,385,217,380,223
|
1550,2322,1926,217,852,313,729,1360,1455,1456,763,966,1046,1009,39,699,374,1266,1220,1768,1416,765,892,394,894,2257,1716,1776,2084,2327,1879,2460,223,2394,1276,590,379,300,1423,1227,1991,380,705,2487,2126,1620,655,1021,1322,1473,398,86,304,907,1434,1190,1790,525,1951,775,506,1391,1797,1242,873,841,1590,1034,5,436,385,451,1341,607,6,1251,1923,575,1042,1490,1598
|
-0.2328390217993925,-0.7495318851344548,-0.43976167580769304,1.1888758808001145,0.2127025180887077,0.8431585826801586,0.31862879037972053,-0.1180065861783075,-0.17512221304650355,-0.17512221304650355,0.2923398612170866,0.13188385952514886,0.07733177575208161,0.10467597056101892,2.9408710467958437,0.3447912610633156,0.7228043903765459,-0.06148029559266701,-0.03343454335768025,-0.350125356105606,-0.14649000038336524,0.2923398612170866,0.18589586847145548,0.698408241052304,0.18589586847145548,-0.6861725882485472,-0.32056824010222307,-0.350125356105606,-0.5308810490428666,-0.7495318851344548,-0.4097204049195783,-0.9111757607706441,1.1665076288666967,-0.8136248100970255,-0.06148029559266701,0.4481994586006217,0.7228043903765459,0.890558218300318,-0.14649000038336524,-0.03343454335768025,-0.4699677127277454,0.7228043903765459,0.3447912610633156,-0.9440776667177786,-0.5615918989070766,-0.2619266677946719,0.39674143767950243,0.10467597056101892,-0.08967050071108885,-0.17512221304650355,0.698408241052304,2.0714733698385936,0.890558218300318,0.18589586847145548,-0.14649000038336524,-0.005531837066441173,-0.350125356105606,0.5244829444562599,-0.43976167580769304,0.2923398612170866,0.5496741112974982,-0.1180065861783075,-0.350125356105606,-0.03343454335768025,0.2127025180887077,0.23937792178355133,-0.2328390217993925,0.10467597056101892,5.198120334434664,0.6492831048866388,0.7228043903765459,0.6245521818790327,-0.08967050071108885,0.4481994586006217,4.890473754334426,-0.03343454335768025,-0.4097204049195783,0.473746678395286,0.10467597056101892,-0.17512221304650355,-0.2328390217993925
| 2,702
|
Entry into host
| 6
| 28
| 2.171187
| 0.029917
|
P19474,Q9BTY2,Q8WTV0,P11279,Q14108,O15118
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,230,69,236,19,24
|
2322,242,24,928,343,619,1220,858,969,2145,821,236,2552,131,1317,766,1568,1276,2566,19,1685,1686,69,1074,230,2217,1705,2220
|
-0.7495318851344548,1.0760900505966375,3.530739879481159,0.15895673427969537,0.7953385242734627,0.4225314103597223,-0.03343454335768025,0.2127025180887077,0.13188385952514886,-0.5924746168808616,0.23937792178355133,1.0988376535312658,-1.1115742979561345,1.5970092420957023,-0.08967050071108885,0.2923398612170866,-0.2328390217993925,-0.06148029559266701,-1.1456872992127736,4.111237733873485,-0.2911692129463672,-0.2911692129463672,2.275479978158442,0.07733177575208161,1.1440456767678313,-0.6235310490678561,-0.2911692129463672,-0.6235310490678561
| 2,702
|
Scaffold protein binding
| 6
| 18
| 2.170663
| 0.029957
|
Q9UQB8,P62258,P08670,Q14790,P07602,O14578
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
32,257,202,303,57,338
|
338,57,1768,202,377,586,1417,1566,257,1683,707,303,1287,1026,1157,2593,880,32
|
0.7953385242734627,2.436706104734128,-0.350125356105606,1.255425828169697,0.7228043903765459,0.4481994586006217,-0.14649000038336524,-0.2328390217993925,1.0303037635203478,-0.2911692129463672,0.3447912610633156,0.890558218300318,-0.06148029559266701,0.10467597056101892,0.02222921008355008,-1.2492972789568666,0.2127025180887077,3.281841750088034
| 2,702
|
Abnormal pericardium morphology
| 6
| 9
| 2.169311
| 0.030059
|
P02545,Q9NZ08,P04062,Q14108,O15460,P14174
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
374,135,443,19,89,218
|
89,374,443,218,2194,1615,19,507,135
|
2.0335184987881214,0.7228043903765459,0.6245521818790327,1.1888758808001145,-0.6235310490678561,-0.2619266677946719,4.111237733873485,0.5496741112974982,1.5970092420957023
| 2,702
|
Lysosomal transport
| 6
| 33
| 2.157684
| 0.030952
|
P11279,Q14108,O14976,O15118,P07602,P11717
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
236,19,117,24,57,120
|
1812,2522,1411,117,24,815,1978,57,892,236,120,268,1422,1882,19,1383,2275,1158,599,1122,510,956,754,2379,1751,880,1252,2217,2316,2022,1004,554,2072
|
-0.37984219227896826,-1.0439690553345753,-0.14649000038336524,1.7196623603455143,3.530739879481159,0.23937792178355133,-0.4699677127277454,2.436706104734128,0.18589586847145548,1.0988376535312658,1.6994156728204817,1.0072634916981495,-0.14649000038336524,-0.4097204049195783,4.111237733873485,-0.1180065861783075,-0.6861725882485472,0.02222921008355008,0.4481994586006217,0.0498499651371408,0.5496741112974982,0.15895673427969537,0.31862879037972053,-0.7814856320202566,-0.32056824010222307,0.2127025180887077,-0.03343454335768025,-0.6235310490678561,-0.7177615370892623,-0.4699677127277454,0.13188385952514886,0.49917415125399284,-0.5003402500028168
| 2,702
|
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
| 9
| 14
| 2.148796
| 0.031651
|
Q07065,Q9BTY2,P14314,Q15084,Q15293,O43852,Q02818,Q5JRA6,Q13217
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
320,230,444,432,82,179,244,545,348
|
179,858,2293,444,561,1502,244,320,348,432,82,545,833,230
|
1.3645361307346424,0.2127025180887077,-0.7177615370892623,0.6245521818790327,0.473746678395286,-0.2039047156366997,1.0760900505966375,0.8431585826801586,0.7953385242734627,0.6492831048866388,2.183727349455117,0.49917415125399284,0.23937792178355133,1.1440456767678313
| 2,702
|
Cation transmembrane transporter activity
| 26
| 68
| 2.148374
| 0.031684
|
O75964,O43772,Q93050,P20674,P61421,P00403,P06576,P08574,Q13423,Q70HW3,P07355,Q9UDW1,Q9Y487,Q9HC21,Q9H2H9,P56385,Q9HD20,P13073,P51790,Q99808,P56134,Q96NB2,Q9Y5K8,O00400,Q7KZN9,P24539
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
256,10,529,649,414,35,292,666,177,49,560,721,78,608,84,347,252,477,368,640,369,511,388,614,504,621
|
614,10,1131,1136,256,818,35,968,1462,1048,292,560,820,969,666,1268,1980,477,702,1503,649,823,1772,1417,621,896,2364,1015,898,1780,1370,2394,368,369,347,414,1680,2127,1786,177,1686,1288,49,504,836,2235,1030,2467,529,2665,1956,511,1440,640,1342,1038,84,1294,608,252,721,1348,2176,1215,78,388,1084,789
|
0.4225314103597223,4.396604319498196,0.02222921008355008,0.02222921008355008,1.0303037635203478,0.23937792178355133,3.1141580717849924,0.13188385952514886,-0.17512221304650355,0.07733177575208161,0.9141025725456303,0.473746678395286,0.23937792178355133,0.13188385952514886,0.37082842982646413,-0.06148029559266701,-0.4699677127277454,0.5747486913303033,0.3447912610633156,-0.2039047156366997,0.39674143767950243,0.23937792178355133,-0.350125356105606,-0.14649000038336524,0.4225314103597223,0.18589586847145548,-0.7814856320202566,0.10467597056101892,0.18589586847145548,-0.350125356105606,-0.1180065861783075,-0.8136248100970255,0.747090864182487,0.747090864182487,0.7953385242734627,0.673901466516914,-0.2911692129463672,-0.5615918989070766,-0.350125356105606,1.386093528320324,-0.2911692129463672,-0.06148029559266701,2.745005746127423,0.5496741112974982,0.23937792178355133,-0.654763070997487,0.10467597056101892,-0.9111757607706441,0.5244829444562599,-1.9147862223575949,-0.43976167580769304,0.5496741112974982,-0.14649000038336524,0.4225314103597223,-0.08967050071108885,0.10467597056101892,2.090348997439926,-0.06148029559266701,0.4481994586006217,1.0532456836169948,0.3447912610633156,-0.08967050071108885,-0.5924746168808616,-0.005531837066441173,2.2206204495029636,0.7228043903765459,0.07733177575208161,0.2923398612170866
| 2,702
|
Fasciculations
| 10
| 32
| 2.142423
| 0.032159
|
O95831,P07196,P51114,Q13510,P22626,Q8NBU5,Q9NQT5,P06280,P07602,P35637
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
39,315,203,111,345,488,152,149,57,155
|
1974,1264,39,2640,149,315,57,1096,1177,891,2415,345,155,2394,203,1882,1148,1021,111,944,978,488,1121,1198,1696,1911,1592,781,686,152,880,494
|
-0.4699677127277454,-0.06148029559266701,2.9408710467958437,-1.6092322015717255,1.4925940643576996,0.8431585826801586,2.436706104734128,0.0498499651371408,-0.005531837066441173,0.18589586847145548,-0.8459514851409792,0.7953385242734627,1.4714633126430223,-0.8136248100970255,1.255425828169697,-0.4097204049195783,0.02222921008355008,0.10467597056101892,1.7799433878907398,0.15895673427969537,0.13188385952514886,0.5747486913303033,0.0498499651371408,-0.005531837066441173,-0.2911692129463672,-0.4097204049195783,-0.2328390217993925,0.2923398612170866,0.37082842982646413,1.4925940643576996,0.2127025180887077,0.5747486913303033
| 2,702
|
Regulation of plasma lipoprotein particle levels
| 7
| 11
| 2.139135
| 0.032425
|
Q6P1A2,Q8WTV0,P09601,P38571,P61978,Q92945,P07355
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
164,69,137,233,301,489,560
|
819,560,137,1012,1365,233,651,301,164,69,489
|
0.23937792178355133,0.473746678395286,1.5762892971839588,0.10467597056101892,-0.1180065861783075,1.1214892721063172,0.39674143767950243,0.890558218300318,1.4289490678170462,2.275479978158442,0.5747486913303033
| 2,702
|
Inorganic anion transport
| 10
| 27
| 2.135784
| 0.032697
|
Q9C0H2,Q9H0H5,O15439,P51790,P45880,Q6N075,Q9Y277,P08183,Q9UHG3,P21796
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
165,102,267,368,23,58,329,189,95,31
|
1867,267,926,764,189,31,412,2688,23,368,2042,1279,1786,1471,1288,58,1586,639,1342,165,102,516,95,329,1215,2616,789
|
-0.4097204049195783,1.0072634916981495,0.15895673427969537,0.2923398612170866,1.3428914236840213,3.281841750088034,0.673901466516914,-3.1850832781614544,3.587597806701549,0.747090864182487,-0.5003402500028168,-0.06148029559266701,-0.350125356105606,-0.17512221304650355,-0.06148029559266701,2.436706104734128,-0.2328390217993925,0.4225314103597223,-0.08967050071108885,1.4289490678170462,1.8592673659235324,0.5496741112974982,1.9567810941536743,0.8431585826801586,-0.005531837066441173,-1.3548673355819485,0.2923398612170866
| 2,702
|
Azurophil granule lumen
| 13
| 41
| 2.134083
| 0.032836
|
P16278,O00560,P10619,Q9BTY2,P17900,O00584,P07437,P61916,P15586,Q9H7Z7,Q92820,P06280,P68371
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,130,163,230,70,103,105,142,174,350,282,149,124
|
130,103,2475,926,2586,582,149,560,105,1096,701,163,1049,174,128,70,2191,1877,1989,2197,2297,938,1882,2655,142,124,1181,1107,1730,348,1947,750,282,1395,2348,1076,530,230,350,2583,1706
|
1.6176488501837785,1.8395473434978173,-0.9440776667177786,0.15895673427969537,-1.2492972789568666,0.4481994586006217,1.4925940643576996,0.473746678395286,1.8395473434978173,0.0498499651371408,0.3447912610633156,1.4289490678170462,0.07733177575208161,1.386093528320324,1.638208714171853,2.2572569188414064,-0.6235310490678561,-0.4097204049195783,-0.4699677127277454,-0.6235310490678561,-0.7177615370892623,0.15895673427969537,-0.4097204049195783,-1.7599354012543078,1.5554884161976426,1.6586894203500797,-0.005531837066441173,0.0498499651371408,-0.32056824010222307,0.7953385242734627,-0.43976167580769304,0.31862879037972053,0.9608846498386505,-0.1180065861783075,-0.7495318851344548,0.07733177575208161,0.5244829444562599,1.1440456767678313,0.7953385242734627,-1.2145462814230732,-0.2911692129463672
| 2,702
|
Clathrin coated endocytic vesicle
| 6
| 16
| 2.132726
| 0.032947
|
P53680,P09497,P20645,Q14108,P11717,P02786
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
318,409,268,19,120,343
|
1555,1711,343,424,409,120,1561,268,900,318,1726,1994,1428,19,1852,1704
|
-0.2328390217993925,-0.32056824010222307,0.7953385242734627,0.6492831048866388,0.673901466516914,1.6994156728204817,-0.2328390217993925,1.0072634916981495,0.18589586847145548,0.8431585826801586,-0.32056824010222307,-0.4699677127277454,-0.14649000038336524,4.111237733873485,-0.37984219227896826,-0.2911692129463672
| 2,702
|
Vacuole organization
| 8
| 36
| 2.132626
| 0.032955
|
P54802,Q16706,P11234,O14773,Q14108,P50897,P11117,Q12768
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,132,231,201,19,52,83,308
|
1812,201,2225,762,443,560,1096,463,83,231,702,1561,1612,2394,1057,52,1422,98,674,1425,1228,308,19,132,1999,2100,1196,956,1751,2381,2217,2022,328,1968,2071,2072
|
-0.37984219227896826,1.255425828169697,-0.654763070997487,0.2923398612170866,0.6245521818790327,0.473746678395286,0.0498499651371408,0.5997077106006617,2.1465741639128653,1.1214892721063172,0.3447912610633156,-0.2328390217993925,-0.2619266677946719,-0.8136248100970255,0.07733177575208161,2.678047917700652,-0.14649000038336524,1.8789142803170127,0.37082842982646413,-0.14649000038336524,-0.03343454335768025,0.8669105116207638,4.111237733873485,1.5970092420957023,-0.4699677127277454,-0.5308810490428666,-0.005531837066441173,0.15895673427969537,-0.32056824010222307,-0.7814856320202566,-0.6235310490678561,-0.4699677127277454,0.8431585826801586,-0.43976167580769304,-0.5003402500028168,-0.5003402500028168
| 2,702
|
Nucleobase containing compound transmembrane transporter activity
| 9
| 14
| 2.131328
| 0.033062
|
L0R6Q1,O15439,Q8TB61,Q99808,Q9HC21,P41440,Q9H2D1,P51991,O00400
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
440,267,528,640,608,115,184,566,614
|
440,614,267,1131,1048,1980,1098,115,566,713,528,640,184,608
|
0.6245521818790327,0.4225314103597223,1.0072634916981495,0.02222921008355008,0.07733177575208161,-0.4699677127277454,0.0498499651371408,1.7398321727024608,0.473746678395286,0.3447912610633156,0.5244829444562599,0.4225314103597223,1.3645361307346424,0.4481994586006217
| 2,702
|
Tclin
| 14
| 77
| 2.13059
| 0.033123
|
P21964,P49721,P28074,P07437,Q99720,P48735,O96000,P04350,Q13885,P06280,Q9BVA1,P68371,P00813,O43676
|
Drugs and Diseases
|
Pharos IDG Category
|
pharos_protein_category
|
34,67,38,105,14,17,172,210,190,149,220,124,93,127
|
2142,1708,127,925,235,1361,730,646,474,856,1415,1499,1931,172,700,286,2355,93,210,968,1462,375,619,149,105,2357,584,463,2578,1269,893,1668,2551,2147,1713,2384,1771,733,34,1982,2150,2387,2152,38,1272,2528,2363,1566,413,1612,17,67,2331,1942,1017,1943,628,124,1683,1575,2268,803,2338,190,544,1998,2505,2465,2646,14,640,2520,603,220,1808,532,1971
|
-0.5924746168808616,-0.32056824010222307,1.638208714171853,0.15895673427969537,1.0988376535312658,-0.1180065861783075,0.31862879037972053,0.39674143767950243,0.5747486913303033,0.2127025180887077,-0.14649000038336524,-0.2039047156366997,-0.43976167580769304,1.386093528320324,0.3447912610633156,0.9375444335085626,-0.7814856320202566,1.9760700997311131,1.2333342498208812,0.13188385952514886,-0.17512221304650355,0.7228043903765459,0.4225314103597223,1.4925940643576996,1.8395473434978173,-0.7814856320202566,0.4481994586006217,0.5997077106006617,-1.2145462814230732,-0.06148029559266701,0.18589586847145548,-0.2911692129463672,-1.1115742979561345,-0.5924746168808616,-0.32056824010222307,-0.8136248100970255,-0.350125356105606,0.31862879037972053,3.1296283127460667,-0.4699677127277454,-0.5924746168808616,-0.8136248100970255,-0.5924746168808616,2.9568654023721628,-0.06148029559266701,-1.0439690553345753,-0.7814856320202566,-0.2328390217993925,0.673901466516914,-0.2619266677946719,4.123983608212495,2.293640144931326,-0.7495318851344548,-0.43976167580769304,0.10467597056101892,-0.43976167580769304,0.4225314103597223,1.6586894203500797,-0.2911692129463672,-0.2328390217993925,-0.6861725882485472,0.2659233011870234,-0.7495318851344548,1.3428914236840213,0.49917415125399284,-0.4699677127277454,-0.977175681919584,-0.9111757607706441,-1.646530754259767,4.199796153109882,0.4225314103597223,-1.0104720506565676,0.4481994586006217,1.1888758808001145,-0.350125356105606,0.5244829444562599,-0.43976167580769304
| 2,702
|
Microbody
| 9
| 49
| 2.126017
| 0.033502
|
Q9BY49,Q9NQG6,O15254,P08670,Q13011,P48735,O75874,Q8N4Q0,P40855
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
129,195,72,202,48,17,54,157,223
|
923,790,1450,72,1131,1601,1456,1008,54,819,202,2079,2147,2552,860,1463,2260,2295,1366,1465,1566,223,17,379,1180,1833,2367,1149,48,2402,274,2050,1476,1154,2001,1951,157,488,1743,1744,993,1163,2102,129,1204,195,453,2493,2241
|
0.15895673427969537,0.2659233011870234,-0.17512221304650355,2.2389705497371217,0.02222921008355008,-0.2619266677946719,-0.17512221304650355,0.10467597056101892,2.558767311500275,0.23937792178355133,1.255425828169697,-0.5308810490428666,-0.5924746168808616,-1.1115742979561345,0.2127025180887077,-0.17512221304650355,-0.6861725882485472,-0.7177615370892623,-0.1180065861783075,-0.17512221304650355,-0.2328390217993925,1.1665076288666967,4.123983608212495,0.7228043903765459,-0.005531837066441173,-0.37984219227896826,-0.7814856320202566,0.02222921008355008,2.745005746127423,-0.8136248100970255,0.9841240598522195,-0.5003402500028168,-0.17512221304650355,0.02222921008355008,-0.4699677127277454,-0.43976167580769304,1.4714633126430223,0.5747486913303033,-0.32056824010222307,-0.32056824010222307,0.13188385952514886,0.02222921008355008,-0.5308810490428666,1.638208714171853,-0.005531837066441173,1.2993373623907043,0.6245521818790327,-0.9440776667177786,-0.654763070997487
| 2,702
|
Juvenile onset
| 15
| 38
| 2.124631
| 0.033617
|
P16278,P54802,P02545,Q14566,P07196,O14773,P38571,Q13510,P06753,P50402,Q03252,P41440,O15118,P06280,Q13144
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,98,374,36,315,201,233,111,297,367,428,115,24,149,181
|
201,24,888,2188,374,2383,149,297,315,128,2386,935,1565,233,2460,115,2499,2196,367,900,1942,2042,98,705,428,2630,181,111,2375,36,1524,1242,1038,1751,641,453,2676,1598
|
1.255425828169697,3.530739879481159,0.18589586847145548,-0.6235310490678561,0.7228043903765459,-0.8136248100970255,1.4925940643576996,0.890558218300318,0.8431585826801586,1.638208714171853,-0.8136248100970255,0.15895673427969537,-0.2328390217993925,1.1214892721063172,-0.9111757607706441,1.7398321727024608,-0.977175681919584,-0.6235310490678561,0.747090864182487,0.18589586847145548,-0.43976167580769304,-0.5003402500028168,1.8789142803170127,0.3447912610633156,0.6492831048866388,-1.4624695189023518,1.3645361307346424,1.7799433878907398,-0.7814856320202566,3.0045553572629977,-0.2039047156366997,-0.03343454335768025,0.10467597056101892,-0.32056824010222307,0.4225314103597223,0.6245521818790327,-2.1964381275798592,-0.2328390217993925
| 2,702
|
Generalized abnormality of skin
| 23
| 177
| 2.121993
| 0.033838
|
P16278,O60568,O43772,P51812,P61916,Q8NB49,Q14108,Q9NWM8,O15118,P06280,P21964,P00403,P10619,Q08J23,Q8IZA0,P37268,Q13126,Q9Y487,O75844,P22830,P00813,P40855,P38571
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,136,10,11,142,146,19,153,24,149,34,35,163,40,178,53,62,78,74,81,93,223,233
|
1351,1353,1175,24,727,2074,2029,2648,10,1263,136,1814,339,816,730,1456,461,616,74,1091,2634,2477,1265,2226,700,2586,35,93,374,443,582,2577,2383,1266,375,149,2458,857,2513,584,163,1010,2669,1097,1222,1979,2652,1223,1713,894,586,128,1012,1099,1769,2149,2385,823,2257,1716,1717,34,81,2151,2082,671,1463,2528,2191,1719,2119,1776,1564,1367,1937,935,1465,1566,898,936,1419,53,2038,1986,413,233,1780,2460,223,2328,1369,2500,1941,2194,1615,1143,379,2671,2332,1180,2042,11,1834,2156,2088,1677,2370,142,1624,416,2127,1059,1786,427,1147,1683,654,1471,428,1839,677,2268,40,655,62,19,1891,1324,359,632,543,2050,977,1234,710,1846,234,908,1383,2406,713,982,2053,1634,524,178,146,435,1069,2236,872,951,2005,1852,1339,1644,2210,755,2059,1958,2379,1700,1403,153,918,1652,660,1405,661,812,2495,696,813,78,1864,1598,2413
|
-0.1180065861783075,-0.1180065861783075,-0.005531837066441173,3.530739879481159,0.31862879037972053,-0.5308810490428666,-0.5003402500028168,-1.6840786597335329,4.396604319498196,-0.06148029559266701,1.5762892971839588,-0.37984219227896826,0.7953385242734627,0.23937792178355133,0.31862879037972053,-0.17512221304650355,0.5997077106006617,0.4225314103597223,2.2206204495029636,0.0498499651371408,-1.5353706399979128,-0.9440776667177786,-0.06148029559266701,-0.654763070997487,0.3447912610633156,-1.2492972789568666,3.1141580717849924,1.9760700997311131,0.7228043903765459,0.6245521818790327,0.4481994586006217,-1.2145462814230732,-0.8136248100970255,-0.06148029559266701,0.7228043903765459,1.4925940643576996,-0.9111757607706441,0.2127025180887077,-1.0104720506565676,0.4481994586006217,1.4289490678170462,0.10467597056101892,-2.0740082524478405,0.0498499651371408,-0.03343454335768025,-0.4699677127277454,-1.7218791207703874,-0.03343454335768025,-0.32056824010222307,0.18589586847145548,0.4481994586006217,1.638208714171853,0.10467597056101892,0.0498499651371408,-0.350125356105606,-0.5924746168808616,-0.8136248100970255,0.23937792178355133,-0.6861725882485472,-0.32056824010222307,-0.32056824010222307,3.1296283127460667,2.183727349455117,-0.5924746168808616,-0.5308810490428666,0.37082842982646413,-0.17512221304650355,-1.0439690553345753,-0.6235310490678561,-0.32056824010222307,-0.5615918989070766,-0.350125356105606,-0.2328390217993925,-0.1180065861783075,-0.43976167580769304,0.15895673427969537,-0.17512221304650355,-0.2328390217993925,0.18589586847145548,0.15895673427969537,-0.14649000038336524,2.6102209682067175,-0.5003402500028168,-0.4699677127277454,0.673901466516914,1.1214892721063172,-0.350125356105606,-0.9111757607706441,1.1665076288666967,-0.7495318851344548,-0.1180065861783075,-0.977175681919584,-0.43976167580769304,-0.6235310490678561,-0.2619266677946719,0.02222921008355008,0.7228043903765459,-2.0740082524478405,-0.7495318851344548,-0.005531837066441173,-0.5003402500028168,4.3359171716292355,-0.37984219227896826,-0.5924746168808616,-0.5308810490428666,-0.2911692129463672,-0.7814856320202566,1.5554884161976426,-0.2619266677946719,0.673901466516914,-0.5615918989070766,0.07733177575208161,-0.350125356105606,0.6492831048866388,0.02222921008355008,-0.2911692129463672,0.39674143767950243,-0.17512221304650355,0.6492831048866388,-0.37984219227896826,0.37082842982646413,-0.6861725882485472,2.892590824162729,0.39674143767950243,2.365660090880429,4.111237733873485,-0.4097204049195783,-0.08967050071108885,0.7712686001756313,0.4225314103597223,0.49917415125399284,-0.5003402500028168,0.13188385952514886,-0.03343454335768025,0.3447912610633156,-0.37984219227896826,1.1214892721063172,0.18589586847145548,-0.1180065861783075,-0.8136248100970255,0.3447912610633156,0.13188385952514886,-0.5003402500028168,-0.2619266677946719,0.5244829444562599,1.386093528320324,1.5136414157872253,0.6492831048866388,0.07733177575208161,-0.654763070997487,0.2127025180887077,0.15895673427969537,-0.4699677127277454,-0.37984219227896826,-0.08967050071108885,-0.2619266677946719,-0.6235310490678561,0.31862879037972053,-0.5003402500028168,-0.43976167580769304,-0.7814856320202566,-0.2911692129463672,-0.1180065861783075,1.4925940643576996,0.18589586847145548,-0.2619266677946719,0.39674143767950243,-0.1180065861783075,0.39674143767950243,0.2659233011870234,-0.9440776667177786,0.37082842982646413,0.2659233011870234,2.2206204495029636,-0.37984219227896826,-0.2328390217993925,-0.8136248100970255
| 2,702
|
Thoracic scoliosis
| 7
| 10
| 2.11777
| 0.034195
|
P02545,O75844,P06753,Q9NSE4,Q9UHX1,O75477,P50542
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
374,74,297,87,553,557,379
|
557,74,374,297,379,654,829,953,87,553
|
0.473746678395286,2.2206204495029636,0.7228043903765459,0.890558218300318,0.7228043903765459,0.39674143767950243,0.23937792178355133,0.15895673427969537,2.0714733698385936,0.49917415125399284
| 2,702
|
Respiratory system development
| 8
| 25
| 2.11406
| 0.03451
|
O95487,O60568,O94788,Q16706,P38571,Q13247,P46379,P00813
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
167,136,8,132,233,249,123,93
|
1085,1812,136,8,167,93,1815,2388,2191,1367,233,123,2367,2546,1374,652,295,1683,2303,249,975,1114,2659,132,1652
|
0.0498499651371408,-0.37984219227896826,1.5762892971839588,4.492217400733412,1.4075642865122227,1.9760700997311131,-0.37984219227896826,-0.8136248100970255,-0.6235310490678561,-0.1180065861783075,1.1214892721063172,1.6586894203500797,-0.7814856320202566,-1.0776690173461208,-0.1180065861783075,0.39674143767950243,0.9141025725456303,-0.2911692129463672,-0.7177615370892623,1.0532456836169948,0.13188385952514886,0.0498499651371408,-1.8368287909913394,1.5970092420957023,-0.2619266677946719
| 2,702
|
Anion transport
| 27
| 66
| 2.113266
| 0.034578
|
O15439,Q8TB61,P45880,P21796,P30536,Q9C0H2,Q9H2D1,Q6N075,Q9Y277,P07602,P08183,P53985,Q9HD26,Q9HC21,Q9H2H9,O43865,P04083,P14174,Q9UHG3,Q9H0H5,P51790,O00400,Q99808,Q96S66,P41440,Q96NB2,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
267,528,23,31,412,165,184,58,329,57,189,192,470,608,84,460,583,218,95,102,368,614,640,639,115,511,516
|
1867,614,267,926,1131,460,889,2575,2658,583,764,1048,619,57,189,969,2669,1980,1098,218,1716,31,1463,412,2688,115,23,2394,368,2042,192,1279,1786,1471,902,1686,866,1288,58,713,2053,528,1586,511,1440,639,640,781,1342,165,102,184,84,1294,608,470,880,516,95,812,329,1215,1043,1084,2616,789
|
-0.4097204049195783,0.4225314103597223,1.0072634916981495,0.15895673427969537,0.02222921008355008,0.5997077106006617,0.18589586847145548,-1.2145462814230732,-1.8368287909913394,0.4481994586006217,0.2923398612170866,0.07733177575208161,0.4225314103597223,2.436706104734128,1.3428914236840213,0.13188385952514886,-2.0740082524478405,-0.4699677127277454,0.0498499651371408,1.1888758808001145,-0.32056824010222307,3.281841750088034,-0.17512221304650355,0.673901466516914,-3.1850832781614544,1.7398321727024608,3.587597806701549,-0.8136248100970255,0.747090864182487,-0.5003402500028168,1.3211587294181275,-0.06148029559266701,-0.350125356105606,-0.17512221304650355,0.18589586847145548,-0.2911692129463672,0.2127025180887077,-0.06148029559266701,2.436706104734128,0.3447912610633156,-0.5003402500028168,0.5244829444562599,-0.2328390217993925,0.5496741112974982,-0.14649000038336524,0.4225314103597223,0.4225314103597223,0.2923398612170866,-0.08967050071108885,1.4289490678170462,1.8592673659235324,1.3645361307346424,2.090348997439926,-0.06148029559266701,0.4481994586006217,0.5997077106006617,0.2127025180887077,0.5496741112974982,1.9567810941536743,0.2659233011870234,0.8431585826801586,-0.005531837066441173,0.10467597056101892,0.07733177575208161,-1.3548673355819485,0.2923398612170866
| 2,702
|
Regulation of immune response
| 24
| 99
| 2.103369
| 0.035434
|
P12956,P19474,Q9NZ08,P09601,P51812,Q8TCT8,Q9NQT5,P28070,P23246,Q9NPR9,O96028,Q15648,Q14790,Q13144,Q5KU26,Q9NUQ9,O43657,P02786,P00813,Q5RKV6,P11279,P41440,Q96PK6,P46379
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
377,131,135,137,11,144,152,159,411,166,407,304,303,181,66,337,79,343,93,225,236,115,246,123
|
1812,1258,1357,79,1978,1414,965,966,407,93,343,583,2414,1768,1416,2562,137,821,765,1269,236,377,1981,794,479,1312,131,411,1053,2387,670,159,2191,1317,1467,651,115,796,1056,2588,123,2394,2462,11,2419,1677,1146,768,628,1625,1839,974,678,1840,902,679,1231,181,1517,1023,2375,743,1685,1151,303,2273,831,304,1434,1026,66,225,1236,1385,1951,144,911,872,840,246,659,2427,2593,436,604,2314,166,514,152,641,1537,337,1540,135,1863,2315,2676,576,813
|
-0.37984219227896826,-0.06148029559266701,-0.1180065861783075,2.202206192643275,-0.4699677127277454,-0.14649000038336524,0.13188385952514886,0.13188385952514886,0.673901466516914,1.9760700997311131,0.7953385242734627,0.4481994586006217,-0.8459514851409792,-0.350125356105606,-0.14649000038336524,-1.1456872992127736,1.5762892971839588,0.23937792178355133,0.2923398612170866,-0.06148029559266701,1.0988376535312658,0.7228043903765459,-0.4699677127277454,0.2659233011870234,0.5747486913303033,-0.08967050071108885,1.5970092420957023,0.673901466516914,0.07733177575208161,-0.8136248100970255,0.37082842982646413,1.4502485272895491,-0.6235310490678561,-0.08967050071108885,-0.17512221304650355,0.39674143767950243,1.7398321727024608,0.2659233011870234,0.07733177575208161,-1.2492972789568666,1.6586894203500797,-0.8136248100970255,-0.9111757607706441,4.3359171716292355,-0.8459514851409792,-0.2911692129463672,0.02222921008355008,0.2923398612170866,0.4225314103597223,-0.2619266677946719,-0.37984219227896826,0.13188385952514886,0.37082842982646413,-0.37984219227896826,0.18589586847145548,0.37082842982646413,-0.03343454335768025,1.3645361307346424,-0.2039047156366997,0.10467597056101892,-0.7814856320202566,0.31862879037972053,-0.2911692129463672,0.02222921008355008,0.890558218300318,-0.6861725882485472,0.23937792178355133,0.890558218300318,-0.14649000038336524,0.10467597056101892,2.329773449633904,1.1665076288666967,-0.03343454335768025,-0.1180065861783075,-0.43976167580769304,1.5346059932631821,0.18589586847145548,0.2127025180887077,0.23937792178355133,1.0760900505966375,0.39674143767950243,-0.8459514851409792,-1.2492972789568666,0.6492831048866388,0.4481994586006217,-0.7177615370892623,1.4289490678170462,0.5496741112974982,1.4925940643576996,0.4225314103597223,-0.2039047156366997,0.8193015508006276,-0.2039047156366997,1.5970092420957023,-0.37984219227896826,-0.7177615370892623,-2.1964381275798592,0.473746678395286,0.2659233011870234
| 2,702
|
Telecanthus
| 8
| 32
| 2.100667
| 0.03567
|
P21964,P02545,Q08J23,P51812,Q86XL3,O75844,P29372,Q03164
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,374,40,11,206,74,346,417
|
1600,2290,74,374,410,2597,1223,1502,823,2257,34,346,1565,1566,1986,1369,11,1834,1729,417,40,1739,908,1524,869,206,2236,872,1587,602,1642,843
|
-0.2619266677946719,-0.7177615370892623,2.2206204495029636,0.7228043903765459,0.673901466516914,-1.2842660323097124,-0.03343454335768025,-0.2039047156366997,0.23937792178355133,-0.6861725882485472,3.1296283127460667,0.7953385242734627,-0.2328390217993925,-0.2328390217993925,-0.4699677127277454,-0.1180065861783075,4.3359171716292355,-0.37984219227896826,-0.32056824010222307,0.673901466516914,2.892590824162729,-0.32056824010222307,0.18589586847145548,-0.2039047156366997,0.2127025180887077,1.255425828169697,-0.654763070997487,0.2127025180887077,-0.2328390217993925,0.4481994586006217,-0.2619266677946719,0.23937792178355133
| 2,702
|
Translocation
| 12
| 45
| 2.097092
| 0.035985
|
Q9BVV7,Q99595,Q9NS69,Q9BTX1,P12270,Q8NFH4,Q12769,Q8N1F7,Q9P2E9,Q9BVL2,Q9Y5J7,P55735
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
451,5,6,468,394,212,280,506,423,385,493,380
|
1549,852,729,1456,763,394,2327,1879,1276,590,1227,380,705,2334,1680,2487,2301,280,1893,1190,868,1790,525,506,212,1391,1121,992,1242,1480,1031,875,1034,5,468,385,451,1341,1650,6,423,1654,1042,493,884
|
-0.2328390217993925,0.2127025180887077,0.31862879037972053,-0.17512221304650355,0.2923398612170866,0.698408241052304,-0.7495318851344548,-0.4097204049195783,-0.06148029559266701,0.4481994586006217,-0.03343454335768025,0.7228043903765459,0.3447912610633156,-0.7495318851344548,-0.2911692129463672,-0.9440776667177786,-0.7177615370892623,0.9608846498386505,-0.4097204049195783,-0.005531837066441173,0.2127025180887077,-0.350125356105606,0.5244829444562599,0.5496741112974982,1.2333342498208812,-0.1180065861783075,0.0498499651371408,0.13188385952514886,-0.03343454335768025,-0.17512221304650355,0.10467597056101892,0.2127025180887077,0.10467597056101892,5.198120334434664,0.5997077106006617,0.7228043903765459,0.6245521818790327,-0.08967050071108885,-0.2619266677946719,4.890473754334426,0.673901466516914,-0.2619266677946719,0.10467597056101892,0.5747486913303033,0.2127025180887077
| 2,702
|
Cachexia
| 7
| 18
| 2.096789
| 0.036012
|
P02545,P38571,P11310,Q99720,P07602,P35637,Q01844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
374,233,141,14,57,155,382
|
816,374,443,57,141,1769,2385,671,1776,155,233,2086,382,1429,14,880,1212,2495
|
0.23937792178355133,0.7228043903765459,0.6245521818790327,2.436706104734128,1.5554884161976426,-0.350125356105606,-0.8136248100970255,0.37082842982646413,-0.350125356105606,1.4714633126430223,1.1214892721063172,-0.5308810490428666,0.7228043903765459,-0.14649000038336524,4.199796153109882,0.2127025180887077,-0.005531837066441173,-0.9440776667177786
| 2,702
|
Depression
| 15
| 90
| 2.096012
| 0.036081
|
P21964,P00403,P06280,Q14139,Q08J23,P51812,Q9BUK6,Q6Y7W6,P50897,Q8WWQ0,O15460,P07602,P35637,Q92804,Q6DKK2
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,35,149,182,40,11,108,110,52,119,89,57,155,250,126
|
1351,2475,89,926,2648,2144,1264,35,443,149,57,1177,891,1010,2669,1269,1980,794,1012,499,34,2152,2191,1719,2364,1937,155,936,1569,796,1056,1369,2588,2121,2461,2394,52,738,2086,11,1782,318,1834,1882,2486,1624,427,2399,1838,40,630,655,2650,1021,182,944,1324,543,262,2404,805,126,1193,110,2572,1120,1159,1392,119,2236,250,872,2540,2006,956,2593,1911,108,1344,2173,880,1652,1041,1964,661,695,2495,2023,1864,644
|
-0.1180065861783075,-0.9440776667177786,2.0335184987881214,0.15895673427969537,-1.6840786597335329,-0.5924746168808616,-0.06148029559266701,3.1141580717849924,0.6245521818790327,1.4925940643576996,2.436706104734128,-0.005531837066441173,0.18589586847145548,0.10467597056101892,-2.0740082524478405,-0.06148029559266701,-0.4699677127277454,0.2659233011870234,0.10467597056101892,0.5496741112974982,3.1296283127460667,-0.5924746168808616,-0.6235310490678561,-0.32056824010222307,-0.7814856320202566,-0.43976167580769304,1.4714633126430223,0.15895673427969537,-0.2328390217993925,0.2659233011870234,0.07733177575208161,-0.1180065861783075,-1.2492972789568666,-0.5615918989070766,-0.9111757607706441,-0.8136248100970255,2.678047917700652,0.31862879037972053,-0.5308810490428666,4.3359171716292355,-0.350125356105606,0.8431585826801586,-0.37984219227896826,-0.4097204049195783,-0.9440776667177786,-0.2619266677946719,0.6492831048866388,-0.8136248100970255,-0.37984219227896826,2.892590824162729,0.4225314103597223,0.39674143767950243,-1.6840786597335329,0.10467597056101892,1.3645361307346424,0.15895673427969537,-0.08967050071108885,0.49917415125399284,1.0303037635203478,-0.8136248100970255,0.2659233011870234,1.6586894203500797,-0.005531837066441173,1.7998858840313976,-1.1800104648843361,0.0498499651371408,0.02222921008355008,-0.1180065861783075,1.7196623603455143,-0.654763070997487,1.0532456836169948,0.2127025180887077,-1.0439690553345753,-0.4699677127277454,0.15895673427969537,-1.2492972789568666,-0.4097204049195783,1.8197536917866635,-0.08967050071108885,-0.5924746168808616,0.2127025180887077,-0.2619266677946719,0.10467597056101892,-0.43976167580769304,0.39674143767950243,0.37082842982646413,-0.9440776667177786,-0.4699677127277454,-0.37984219227896826,0.4225314103597223
| 2,702
|
Regulation of mrna processing
| 31
| 80
| 2.095207
| 0.036153
|
P84103,Q9Y2W1,Q13573,Q5VTR2,Q9UHX1,Q96MU7,Q9BWF3,P98175,Q9H2U1,P09012,P17844,Q07666,P38159,P61978,Q69YN4,Q96T37,O75494,P50750,Q92879,P51116,P51114,P62995,Q08170,O43865,P22626,P19338,Q16629,P98179,Q13242,Q8NDT2,Q13247
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
500,405,520,523,553,684,687,416,691,408,537,678,176,301,434,450,558,564,600,71,203,465,593,460,345,344,633,106,370,245,249
|
1866,1352,2248,460,1089,558,1606,408,891,892,1817,537,1770,1715,344,345,971,1363,1877,1985,176,825,564,1226,203,71,1105,673,1227,301,465,2443,500,416,106,1729,974,678,593,1840,1230,1577,370,249,520,1732,1430,1187,1474,709,1234,2425,633,1633,1327,523,434,1478,1331,1193,1385,776,2408,2003,910,245,1243,600,914,684,1589,1909,450,687,691,1401,553,1596,405,1707
|
-0.4097204049195783,-0.1180065861783075,-0.6861725882485472,0.5997077106006617,0.0498499651371408,0.473746678395286,-0.2619266677946719,0.673901466516914,0.18589586847145548,0.18589586847145548,-0.37984219227896826,0.49917415125399284,-0.350125356105606,-0.32056824010222307,0.7953385242734627,0.7953385242734627,0.13188385952514886,-0.1180065861783075,-0.4097204049195783,-0.4699677127277454,1.386093528320324,0.23937792178355133,0.473746678395286,-0.03343454335768025,1.255425828169697,2.2572569188414064,0.0498499651371408,0.37082842982646413,-0.03343454335768025,0.890558218300318,0.5997077106006617,-0.8784677570852006,0.5496741112974982,0.673901466516914,1.8395473434978173,-0.32056824010222307,0.13188385952514886,0.37082842982646413,0.4481994586006217,-0.37984219227896826,-0.03343454335768025,-0.2328390217993925,0.747090864182487,1.0532456836169948,0.5244829444562599,-0.32056824010222307,-0.14649000038336524,-0.005531837066441173,-0.17512221304650355,0.3447912610633156,-0.03343454335768025,-0.8459514851409792,0.4225314103597223,-0.2619266677946719,-0.08967050071108885,0.5244829444562599,0.6492831048866388,-0.17512221304650355,-0.08967050071108885,-0.005531837066441173,-0.1180065861783075,0.2923398612170866,-0.8136248100970255,-0.4699677127277454,0.18589586847145548,1.0760900505966375,-0.03343454335768025,0.4481994586006217,0.18589586847145548,0.37082842982646413,-0.2328390217993925,-0.4097204049195783,0.6245521818790327,0.37082842982646413,0.37082842982646413,-0.1180065861783075,0.49917415125399284,-0.2328390217993925,0.698408241052304,-0.2911692129463672
| 2,702
|
PDZ domain [IPR001478]
| 7
| 17
| 2.094828
| 0.036186
|
O00560,Q14168,O00233,Q9HD26,Q96L92,Q9Y4G8,Q9UDY2
|
Sequence
|
InterPro Domain
|
interpro_domain
|
130,501,473,470,510,254,552
|
962,473,130,1175,1144,1509,1510,1108,594,1431,501,1328,510,470,1755,552,254
|
0.13188385952514886,0.5747486913303033,1.6176488501837785,-0.005531837066441173,0.02222921008355008,-0.2039047156366997,-0.2039047156366997,0.0498499651371408,0.4481994586006217,-0.14649000038336524,0.5496741112974982,-0.08967050071108885,0.5496741112974982,0.5997077106006617,-0.32056824010222307,0.49917415125399284,1.0532456836169948
| 2,702
|
Abnormality of fontanelles
| 10
| 41
| 2.092737
| 0.036373
|
P02545,Q32P28,P50542,Q08J23,Q9Y487,P51812,O75844,O75419,P98175,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
374,68,379,40,78,11,74,392,416,223
|
1353,1450,1456,392,1414,518,74,374,1223,1051,649,2257,2083,1564,898,2038,1986,1780,223,1612,1369,2500,379,1833,11,2088,416,427,40,2535,1632,1433,908,68,713,1901,874,2005,696,78,1084
|
-0.1180065861783075,-0.17512221304650355,-0.17512221304650355,0.698408241052304,-0.14649000038336524,0.5244829444562599,2.2206204495029636,0.7228043903765459,-0.03343454335768025,0.07733177575208161,0.39674143767950243,-0.6861725882485472,-0.5308810490428666,-0.2328390217993925,0.18589586847145548,-0.5003402500028168,-0.4699677127277454,-0.350125356105606,1.1665076288666967,-0.2619266677946719,-0.1180065861783075,-0.977175681919584,0.7228043903765459,-0.37984219227896826,4.3359171716292355,-0.5308810490428666,0.673901466516914,0.6492831048866388,2.892590824162729,-1.0439690553345753,-0.2619266677946719,-0.14649000038336524,0.18589586847145548,2.293640144931326,0.3447912610633156,-0.4097204049195783,0.2127025180887077,-0.4699677127277454,0.37082842982646413,2.2206204495029636,0.07733177575208161
| 2,702
|
Hydrolase
| 44
| 334
| 2.085643
| 0.037011
|
P42785,Q9NPH0,P16278,Q8IV08,Q8NCC3,Q9NZ08,Q16706,Q9UQ84,Q8TCT8,P07099,Q8NHP8,Q16740,P06280,Q9HB40,P10619,Q14566,P28074,P06865,Q9UIQ6,Q9H3G5,Q9H089,O60502,P15586,Q9H6V9,P50897,Q86UV5,Q969T7,P17900,O75976,O14773,O75844,P42892,P11117,Q96K76,P55786,P00813,P54802,Q99538,Q9BTY2,O00584,P11234,P38571,Q13510,Q8N2K0
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
0,1,128,4,134,135,132,15,144,18,147,25,149,29,163,36,38,168,45,44,171,46,174,51,52,183,194,70,196,201,74,80,83,90,92,93,98,99,230,103,231,233,111,113
|
2585,1085,1409,2182,1300,790,2321,1258,103,2027,2475,1259,201,1356,2223,1358,886,926,1007,1872,1453,2323,363,46,1088,2324,1497,1553,74,196,1664,1307,1308,2291,1265,1500,967,93,443,582,149,168,18,2189,1096,1768,701,1311,1815,463,2358,163,2146,83,892,476,231,2652,377,1981,2114,793,2552,174,128,364,537,70,479,1769,2481,1312,2385,2482,1561,823,2080,795,932,2151,2565,2360,622,38,2528,1506,2389,1984,346,1877,2435,1610,2688,2192,1778,1316,2670,2529,898,2701,1567,1824,233,1611,2599,2555,2329,1826,1102,937,355,2039,0,80,1613,1614,1369,2264,2498,2296,2194,1103,1275,2394,1104,1143,900,52,1831,1422,2462,1508,2367,2645,1227,1675,2396,98,1616,1882,2419,1677,92,2532,1424,2546,1785,2335,2157,2123,1374,2440,1228,2203,769,592,2662,1427,2399,1839,2268,1840,1377,2047,111,2338,2685,829,1378,1113,483,2339,744,1188,36,2161,1735,303,1325,1737,1631,262,2376,2657,1997,866,132,25,1525,1581,546,1791,1742,1477,2547,1583,1330,1528,401,983,1896,1238,2537,1194,1897,2276,2130,332,183,946,1119,4,2615,682,1793,989,1692,1903,2277,113,2164,239,1068,837,134,716,147,467,2101,144,717,1335,2345,1798,1954,2646,282,1243,950,1745,1199,1587,874,194,2540,2007,572,90,2311,1439,876,1247,284,2593,99,2559,780,2312,2211,551,2102,844,530,2009,230,1292,2470,452,1485,1534,2314,171,1804,1486,1206,691,2239,44,2013,2014,2611,51,2694,2015,2016,1859,916,29,1860,1,1649,785,879,693,1536,1861,1402,960,847,917,1165,2281,2172,1651,1404,2216,135,848,1652,2065,45,722,2284,2452,2218,2022,1171,725,920,15,1172,1967,2318,2473,439,1349,2320,1809,813,644,1491,2026,1972,494
|
-1.2492972789568666,0.0498499651371408,-0.14649000038336524,-0.6235310490678561,-0.08967050071108885,0.2659233011870234,-0.7495318851344548,-0.06148029559266701,1.8395473434978173,-0.5003402500028168,-0.9440776667177786,-0.06148029559266701,1.255425828169697,-0.1180065861783075,-0.654763070997487,-0.1180065861783075,0.18589586847145548,0.15895673427969537,0.10467597056101892,-0.4097204049195783,-0.17512221304650355,-0.7495318851344548,0.747090864182487,2.7781653386568346,0.0498499651371408,-0.7495318851344548,-0.2039047156366997,-0.2328390217993925,2.2206204495029636,1.2774266291404368,-0.2911692129463672,-0.08967050071108885,-0.08967050071108885,-0.7177615370892623,-0.06148029559266701,-0.2039047156366997,0.13188385952514886,1.9760700997311131,0.6245521818790327,0.4481994586006217,1.4925940643576996,1.4075642865122227,4.111237733873485,-0.6235310490678561,0.0498499651371408,-0.350125356105606,0.3447912610633156,-0.08967050071108885,-0.37984219227896826,0.5997077106006617,-0.7814856320202566,1.4289490678170462,-0.5924746168808616,2.1465741639128653,0.18589586847145548,0.5747486913303033,1.1214892721063172,-1.7218791207703874,0.7228043903765459,-0.4699677127277454,-0.5615918989070766,0.2659233011870234,-1.1115742979561345,1.386093528320324,1.638208714171853,0.747090864182487,0.49917415125399284,2.2572569188414064,0.5747486913303033,-0.350125356105606,-0.9440776667177786,-0.08967050071108885,-0.8136248100970255,-0.9440776667177786,-0.2328390217993925,0.23937792178355133,-0.5308810490428666,0.2659233011870234,0.15895673427969537,-0.5924746168808616,-1.1456872992127736,-0.7814856320202566,0.4225314103597223,2.9568654023721628,-1.0439690553345753,-0.2039047156366997,-0.8136248100970255,-0.4699677127277454,0.7953385242734627,-0.4097204049195783,-0.8784677570852006,-0.2619266677946719,-3.1850832781614544,-0.6235310490678561,-0.350125356105606,-0.08967050071108885,-2.0740082524478405,-1.0439690553345753,0.18589586847145548,-14.287076023591291,-0.2328390217993925,-0.37984219227896826,1.1214892721063172,-0.2619266677946719,-1.2842660323097124,-1.1115742979561345,-0.7495318851344548,-0.37984219227896826,0.0498499651371408,0.15895673427969537,0.7712686001756313,-0.5003402500028168,6.217718739388483,2.202206192643275,-0.2619266677946719,-0.2619266677946719,-0.1180065861783075,-0.6861725882485472,-0.977175681919584,-0.7177615370892623,-0.6235310490678561,0.0498499651371408,-0.06148029559266701,-0.8136248100970255,0.0498499651371408,0.02222921008355008,0.18589586847145548,2.678047917700652,-0.37984219227896826,-0.14649000038336524,-0.9111757607706441,-0.2039047156366997,-0.7814856320202566,-1.646530754259767,-0.03343454335768025,-0.2911692129463672,-0.8136248100970255,1.8789142803170127,-0.2619266677946719,-0.4097204049195783,-0.8459514851409792,-0.2911692129463672,2.0144383197469633,-1.0439690553345753,-0.14649000038336524,-1.0776690173461208,-0.350125356105606,-0.7495318851344548,-0.5924746168808616,-0.5615918989070766,-0.1180065861783075,-0.8784677570852006,-0.03343454335768025,-0.6235310490678561,0.2923398612170866,0.4481994586006217,-1.8756727477583501,-0.14649000038336524,-0.8136248100970255,-0.37984219227896826,-0.6861725882485472,-0.37984219227896826,-0.1180065861783075,-0.5003402500028168,1.7799433878907398,-0.7495318851344548,-2.8054927922613717,0.23937792178355133,-0.1180065861783075,0.0498499651371408,0.5747486913303033,-0.7495318851344548,0.31862879037972053,-0.005531837066441173,3.0045553572629977,-0.5924746168808616,-0.32056824010222307,0.890558218300318,-0.08967050071108885,-0.32056824010222307,-0.2619266677946719,1.0303037635203478,-0.7814856320202566,-1.7982508277275122,-0.4699677127277454,0.2127025180887077,1.5970092420957023,3.502073656744272,-0.2039047156366997,-0.2328390217993925,0.49917415125399284,-0.350125356105606,-0.32056824010222307,-0.17512221304650355,-1.0776690173461208,-0.2328390217993925,-0.08967050071108885,-0.2039047156366997,0.698408241052304,0.13188385952514886,-0.4097204049195783,-0.03343454335768025,-1.0439690553345753,-0.005531837066441173,-0.4097204049195783,-0.6861725882485472,-0.5615918989070766,0.8193015508006276,1.3645361307346424,0.15895673427969537,0.0498499651371408,5.2288928568634425,-1.3548673355819485,0.37082842982646413,-0.350125356105606,0.13188385952514886,-0.2911692129463672,-0.4097204049195783,-0.6861725882485472,1.7599256653622593,-0.5924746168808616,1.0988376535312658,0.07733177575208161,0.23937792178355133,1.5970092420957023,0.3447912610633156,1.5136414157872253,0.5997077106006617,-0.5308810490428666,1.5346059932631821,0.3447912610633156,-0.08967050071108885,-0.7495318851344548,-0.350125356105606,-0.43976167580769304,-1.646530754259767,0.9608846498386505,-0.03343454335768025,0.15895673427969537,-0.32056824010222307,-0.005531837066441173,-0.2328390217993925,0.2127025180887077,1.3211587294181275,-1.0439690553345753,-0.4699677127277454,0.473746678395286,2.0335184987881214,-0.7177615370892623,-0.14649000038336524,0.2127025180887077,-0.03343454335768025,0.9608846498386505,-1.2492972789568666,1.8789142803170127,-1.1115742979561345,0.2923398612170866,-0.7177615370892623,-0.6235310490678561,0.49917415125399284,-0.5308810490428666,0.23937792178355133,0.5244829444562599,-0.4699677127277454,1.1440456767678313,-0.06148029559266701,-0.9111757607706441,0.6245521818790327,-0.17512221304650355,-0.2039047156366997,-0.7177615370892623,1.4075642865122227,-0.350125356105606,-0.17512221304650355,-0.005531837066441173,0.37082842982646413,-0.654763070997487,2.827512784417395,-0.4699677127277454,-0.4699677127277454,-1.3194551620520436,2.7283466065358986,-4.625388979492895,-0.4699677127277454,-0.4699677127277454,-0.37984219227896826,0.18589586847145548,3.341494967883903,-0.37984219227896826,6.184106568144779,-0.2619266677946719,0.2923398612170866,0.2127025180887077,0.37082842982646413,-0.2039047156366997,-0.37984219227896826,-0.1180065861783075,0.15895673427969537,0.23937792178355133,0.18589586847145548,0.02222921008355008,-0.6861725882485472,-0.5924746168808616,-0.2619266677946719,-0.1180065861783075,-0.6235310490678561,1.5970092420957023,0.23937792178355133,-0.2619266677946719,-0.5003402500028168,2.827512784417395,0.3447912610633156,-0.6861725882485472,-0.8784677570852006,-0.6235310490678561,-0.4699677127277454,0.02222921008355008,0.3447912610633156,0.18589586847145548,4.1620309901270245,0.02222921008355008,-0.43976167580769304,-0.7177615370892623,-0.9111757607706441,0.6492831048866388,-0.08967050071108885,-0.7177615370892623,-0.350125356105606,0.2659233011870234,0.4225314103597223,-0.17512221304650355,-0.4699677127277454,-0.43976167580769304,0.5747486913303033
| 2,702
|
Post chaperonin tubulin folding pathway
| 7
| 10
| 2.08087
| 0.037446
|
O75347,P36404,Q9BUF5,P04350,Q9BVA1,P68371,Q13885
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
556,540,603,210,220,124,190
|
556,210,540,124,190,1433,1532,686,603,220
|
0.473746678395286,1.2333342498208812,0.49917415125399284,1.6586894203500797,1.3428914236840213,-0.14649000038336524,-0.2039047156366997,0.37082842982646413,0.4481994586006217,1.1888758808001145
| 2,702
|
Lipid metabolism
| 19
| 109
| 2.080152
| 0.037512
|
Q9NPH0,Q9BY49,Q8NCC3,P61916,P11310,Q8NHP8,O15118,Q16850,P48449,Q13011,Q9H6V9,P37268,P07602,P17900,O15254,P23786,Q13510,Q15392,Q8N2K0
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
1,129,134,142,141,147,24,26,43,48,51,53,57,70,72,88,111,112,113
|
1658,923,2182,2695,1301,555,24,72,727,2074,1601,557,1497,2032,664,2291,648,819,341,2382,2586,443,2693,57,2079,1815,141,2692,1713,1558,70,1312,2190,88,1504,934,1877,1313,1366,237,53,233,1468,1101,2039,2518,43,2500,2194,1615,1422,1180,1833,2297,798,1572,142,2267,1229,677,1149,48,2697,111,2402,359,2624,274,1631,2050,1114,112,1846,804,503,26,1380,2446,746,164,2053,773,2001,2131,113,134,637,147,1744,2674,1070,1338,2666,1644,1801,2507,129,2061,51,350,1,1959,787,2173,1253,660,1297,455,494
|
-0.2911692129463672,0.15895673427969537,-0.6235310490678561,-4.8821959377233615,-0.08967050071108885,0.473746678395286,3.530739879481159,2.2389705497371217,0.31862879037972053,-0.5308810490428666,-0.2619266677946719,0.473746678395286,-0.2039047156366997,-0.5003402500028168,0.37082842982646413,-0.7177615370892623,0.39674143767950243,0.23937792178355133,0.7953385242734627,-0.8136248100970255,-1.2492972789568666,0.6245521818790327,-4.501064891738855,2.436706104734128,-0.5308810490428666,-0.37984219227896826,1.5554884161976426,-4.260046503957561,-0.32056824010222307,-0.2328390217993925,2.2572569188414064,-0.08967050071108885,-0.6235310490678561,2.0525300254302943,-0.2039047156366997,0.15895673427969537,-0.4097204049195783,-0.08967050071108885,-0.1180065861783075,1.0988376535312658,2.6102209682067175,1.1214892721063172,-0.17512221304650355,0.0498499651371408,-0.5003402500028168,-1.0104720506565676,2.827512784417395,-0.977175681919584,-0.6235310490678561,-0.2619266677946719,-0.14649000038336524,-0.005531837066441173,-0.37984219227896826,-0.7177615370892623,0.2659233011870234,-0.2328390217993925,1.5554884161976426,-0.6861725882485472,-0.03343454335768025,0.37082842982646413,0.02222921008355008,2.745005746127423,-5.150367307121161,1.7799433878907398,-0.8136248100970255,0.7712686001756313,-1.4263717244472445,0.9841240598522195,-0.2619266677946719,-0.5003402500028168,0.0498499651371408,1.7599256653622593,-0.37984219227896826,0.2659233011870234,0.5496741112974982,3.487680492801992,-0.1180065861783075,-0.8784677570852006,0.31862879037972053,1.4289490678170462,-0.5003402500028168,0.2923398612170866,-0.4699677127277454,-0.5615918989070766,1.7599256653622593,1.5970092420957023,0.4225314103597223,1.5136414157872253,-0.32056824010222307,-2.1553332825055893,0.07733177575208161,-0.08967050071108885,-1.9147862223575949,-0.2619266677946719,-0.350125356105606,-0.977175681919584,1.638208714171853,-0.5003402500028168,2.7283466065358986,0.7953385242734627,6.184106568144779,-0.43976167580769304,0.2923398612170866,-0.5924746168808616,-0.03343454335768025,0.39674143767950243,-0.06148029559266701,0.6245521818790327,0.5747486913303033
| 2,702
|
Organophosphate ester transport
| 7
| 26
| 2.080082
| 0.037518
|
Q8WTV0,P61916,Q8NB49,Q14108,Q9H2D1,P41440,P08183
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
69,142,146,19,184,115,189
|
614,267,1131,1048,189,1980,1098,669,860,2688,115,2193,142,902,19,1288,713,146,528,1586,69,640,2104,184,608,1296
|
0.4225314103597223,1.0072634916981495,0.02222921008355008,0.07733177575208161,1.3428914236840213,-0.4699677127277454,0.0498499651371408,0.37082842982646413,0.2127025180887077,-3.1850832781614544,1.7398321727024608,-0.6235310490678561,1.5554884161976426,0.18589586847145548,4.111237733873485,-0.06148029559266701,0.3447912610633156,1.5136414157872253,0.5244829444562599,-0.2328390217993925,2.275479978158442,0.4225314103597223,-0.5308810490428666,1.3645361307346424,0.4481994586006217,-0.06148029559266701
| 2,702
|
Protein targeting
| 15
| 91
| 2.079085
| 0.03761
|
P43307,O00560,Q9NQG6,Q99595,Q9NS69,O95831,P62258,Q8N4H5,O60725,Q14108,Q15388,P46379,P55786,O14737,P40855
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,130,195,5,6,39,257,138,114,19,86,123,92,217,223
|
1549,1351,1812,130,2522,217,852,1411,729,926,1710,114,1456,2324,2250,966,2525,39,699,1768,2325,765,892,587,268,1672,2565,412,1315,897,2084,1938,223,160,123,1941,1674,379,1422,1832,92,1509,2334,1785,2335,1680,627,257,1622,652,1375,1110,1284,19,1737,86,1893,1026,1190,867,546,2572,2696,525,2275,2343,138,1743,335,2492,5,780,451,1204,607,195,6,2381,532,1653,611,2021,1923,2022,554,2071,1043,1490,493,884,312
|
-0.2328390217993925,-0.1180065861783075,-0.37984219227896826,1.6176488501837785,-1.0439690553345753,1.1888758808001145,0.2127025180887077,-0.14649000038336524,0.31862879037972053,0.15895673427969537,-0.32056824010222307,1.7398321727024608,-0.17512221304650355,-0.7495318851344548,-0.6861725882485472,0.13188385952514886,-1.0439690553345753,2.9408710467958437,0.3447912610633156,-0.350125356105606,-0.7495318851344548,0.2923398612170866,0.18589586847145548,0.4481994586006217,1.0072634916981495,-0.2911692129463672,-1.1456872992127736,0.673901466516914,-0.08967050071108885,0.18589586847145548,-0.5308810490428666,-0.43976167580769304,1.1665076288666967,1.4502485272895491,1.6586894203500797,-0.43976167580769304,-0.2911692129463672,0.7228043903765459,-0.14649000038336524,-0.37984219227896826,2.0144383197469633,-0.2039047156366997,-0.7495318851344548,-0.350125356105606,-0.7495318851344548,-0.2911692129463672,0.4225314103597223,1.0303037635203478,-0.2619266677946719,0.39674143767950243,-0.1180065861783075,0.0498499651371408,-0.06148029559266701,4.111237733873485,-0.32056824010222307,2.0714733698385936,-0.4097204049195783,0.10467597056101892,-0.005531837066441173,0.2127025180887077,0.49917415125399284,-1.1800104648843361,-4.8821959377233615,0.5244829444562599,-0.6861725882485472,-0.7495318851344548,1.5762892971839588,-0.32056824010222307,0.8193015508006276,-0.9440776667177786,5.198120334434664,0.2923398612170866,0.6245521818790327,-0.005531837066441173,0.4481994586006217,1.2993373623907043,4.890473754334426,-0.7814856320202566,0.5244829444562599,-0.2619266677946719,0.4481994586006217,-0.4699677127277454,-0.4097204049195783,-0.4699677127277454,0.49917415125399284,-0.5003402500028168,0.10467597056101892,-0.17512221304650355,0.5747486913303033,0.2127025180887077,0.8669105116207638
| 2,702
|
Metapathway biotransformation phase i and ii
| 6
| 21
| 2.078845
| 0.037632
|
Q8NEC7,P21964,P07099,Q9H2H9,Q16850,P00390
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
162,34,18,84,26,286
|
1449,1813,286,18,2294,2384,2617,34,1563,2484,770,26,681,1530,322,162,1801,2106,1750,84,2241
|
-0.17512221304650355,-0.37984219227896826,0.9375444335085626,4.111237733873485,-0.7177615370892623,-0.8136248100970255,-1.3905052682383434,3.1296283127460667,-0.2328390217993925,-0.9440776667177786,0.2923398612170866,3.487680492801992,0.37082842982646413,-0.2039047156366997,0.8431585826801586,1.4502485272895491,-0.350125356105606,-0.5308810490428666,-0.32056824010222307,2.090348997439926,-0.654763070997487
| 2,702
|
Phospholipid binding
| 17
| 76
| 2.077617
| 0.037745
|
O00560,O60443,Q8NCC3,Q9Y5X3,Q8WTV0,Q9H0H5,O14773,P35080,Q14108,P50897,O60313,Q9H6U6,P45880,Q9Y4G8,P07602,O15020,P21796
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
130,65,134,406,69,102,201,365,19,52,363,185,23,254,57,285,31
|
389,1973,2691,130,201,1411,285,1660,815,1493,363,65,928,442,1496,583,560,57,1177,820,2562,2563,892,1097,895,1716,31,669,1774,1776,365,1879,23,2656,1722,2193,52,738,1278,427,1320,1889,1428,1628,864,19,595,632,1329,2275,807,134,1391,69,777,1954,1641,2468,510,2210,1802,915,2104,102,185,880,2316,576,2067,1759,1298,2072,1597,254,1811,406
|
0.698408241052304,-0.4699677127277454,-4.143157661047852,1.6176488501837785,1.255425828169697,-0.14649000038336524,0.9375444335085626,-0.2911692129463672,0.23937792178355133,-0.2039047156366997,0.747090864182487,2.329773449633904,0.15895673427969537,0.6245521818790327,-0.2039047156366997,0.4481994586006217,0.473746678395286,2.436706104734128,-0.005531837066441173,0.23937792178355133,-1.1456872992127736,-1.1456872992127736,0.18589586847145548,0.0498499651371408,0.18589586847145548,-0.32056824010222307,3.281841750088034,0.37082842982646413,-0.350125356105606,-0.350125356105606,0.747090864182487,-0.4097204049195783,3.587597806701549,-1.7982508277275122,-0.32056824010222307,-0.6235310490678561,2.678047917700652,0.31862879037972053,-0.06148029559266701,0.6492831048866388,-0.08967050071108885,-0.4097204049195783,-0.14649000038336524,-0.2619266677946719,0.2127025180887077,4.111237733873485,0.4481994586006217,0.4225314103597223,-0.08967050071108885,-0.6861725882485472,0.2659233011870234,1.5970092420957023,-0.1180065861783075,2.275479978158442,0.2923398612170866,-0.43976167580769304,-0.2619266677946719,-0.9111757607706441,0.5496741112974982,-0.6235310490678561,-0.350125356105606,0.18589586847145548,-0.5308810490428666,1.8592673659235324,1.3645361307346424,0.2127025180887077,-0.7177615370892623,0.473746678395286,-0.5003402500028168,-0.32056824010222307,-0.06148029559266701,-0.5003402500028168,-0.2328390217993925,1.0532456836169948,-0.350125356105606,0.698408241052304
| 2,702
|
Parkinsons disease
| 8
| 50
| 2.075717
| 0.03792
|
P00403,P06576,O96000,P14406,P45880,P22695,O43676,P21796
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
35,292,172,22,23,122,127,31
|
2142,1708,1764,127,925,1361,730,646,1136,474,856,1415,1499,1931,172,35,1048,292,666,1876,1268,1980,1098,477,22,1669,1771,649,31,1717,2415,122,621,896,1272,1719,2364,1015,23,1370,2331,1017,1375,1684,544,1998,2593,721,329,1971
|
-0.5924746168808616,-0.32056824010222307,-0.350125356105606,1.638208714171853,0.15895673427969537,-0.1180065861783075,0.31862879037972053,0.39674143767950243,0.02222921008355008,0.5747486913303033,0.2127025180887077,-0.14649000038336524,-0.2039047156366997,-0.43976167580769304,1.386093528320324,3.1141580717849924,0.07733177575208161,0.9141025725456303,0.37082842982646413,-0.4097204049195783,-0.06148029559266701,-0.4699677127277454,0.0498499651371408,0.5747486913303033,3.643834047397023,-0.2911692129463672,-0.350125356105606,0.39674143767950243,3.281841750088034,-0.32056824010222307,-0.8459514851409792,1.6586894203500797,0.4225314103597223,0.18589586847145548,-0.06148029559266701,-0.32056824010222307,-0.7814856320202566,0.10467597056101892,3.587597806701549,-0.1180065861783075,-0.7495318851344548,0.10467597056101892,-0.1180065861783075,-0.2911692129463672,0.49917415125399284,-0.4699677127277454,-1.2492972789568666,0.3447912610633156,0.8431585826801586,-0.43976167580769304
| 2,702
|
Nuclear inner membrane
| 9
| 18
| 2.07421
| 0.03806
|
Q8IXM6,Q14739,Q99720,O75844,P50402,P62995,Q9Y2U8,Q03252,P20700
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
263,359,14,74,367,465,353,428,499
|
74,2032,499,1469,796,367,2487,465,428,568,359,1382,263,14,1443,2238,919,353
|
2.2206204495029636,-0.5003402500028168,0.5496741112974982,-0.17512221304650355,0.2659233011870234,0.747090864182487,-0.9440776667177786,0.5997077106006617,0.6492831048866388,0.473746678395286,0.7712686001756313,-0.1180065861783075,1.0303037635203478,4.199796153109882,-0.14649000038336524,-0.654763070997487,0.18589586847145548,0.7953385242734627
| 2,702
|
Hydrolase activity acting on glycosyl bonds
| 10
| 25
| 2.072055
| 0.03826
|
P16278,P54802,Q9BTY2,P17900,Q16706,P06865,P04062,O60502,P29372,P06280
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,98,230,70,132,168,443,46,346,149
|
2475,886,46,762,443,582,149,168,1096,701,463,1979,128,70,1053,2565,346,2529,98,592,829,1735,132,230,847
|
-0.9440776667177786,0.18589586847145548,2.7781653386568346,0.2923398612170866,0.6245521818790327,0.4481994586006217,1.4925940643576996,1.4075642865122227,0.0498499651371408,0.3447912610633156,0.5997077106006617,-0.4699677127277454,1.638208714171853,2.2572569188414064,0.07733177575208161,-1.1456872992127736,0.7953385242734627,-1.0439690553345753,1.8789142803170127,0.4481994586006217,0.23937792178355133,-0.32056824010222307,1.5970092420957023,1.1440456767678313,0.23937792178355133
| 2,702
|
Abnormal biliary tract morphology
| 8
| 21
| 2.07188
| 0.038277
|
Q14739,P02545,P09601,Q14108,P14174,P07602,Q9NSD9,P50542
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
359,374,137,19,218,57,327,379
|
926,374,443,57,137,218,2617,1567,379,1833,1110,655,19,359,1118,1587,327,880,2472,2023,1598
|
0.15895673427969537,0.7228043903765459,0.6245521818790327,2.436706104734128,1.5762892971839588,1.1888758808001145,-1.3905052682383434,-0.2328390217993925,0.7228043903765459,-0.37984219227896826,0.0498499651371408,0.39674143767950243,4.111237733873485,0.7712686001756313,0.0498499651371408,-0.2328390217993925,0.8431585826801586,0.2127025180887077,-0.9111757607706441,-0.4699677127277454,-0.2328390217993925
| 2,702
|
Abnormality of the upper respiratory tract
| 17
| 84
| 2.068642
| 0.03858
|
P16278,P21964,P54802,P28070,Q15165,Q14739,Q86U42,Q13510,P15586,P29372,Q96HY6,O15460,P07602,P35637,P00813,Q92804,Q13432
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,34,98,159,262,359,305,111,174,346,276,89,57,155,93,250,161
|
1085,2475,1302,1353,1600,89,1814,816,2290,1264,1265,2355,93,374,582,1266,857,57,1177,701,891,1010,174,128,1051,2257,1716,34,2553,159,346,155,898,1567,1611,2460,2517,796,1056,1369,1057,738,1508,1782,1834,98,1882,2335,427,1888,1021,707,161,111,944,359,1061,262,1234,2405,869,2205,305,2002,1390,1334,2236,683,250,872,1587,2005,601,1907,276,1911,2620,1038,1487,918,880,1652,660,553
|
0.0498499651371408,-0.9440776667177786,-0.08967050071108885,-0.1180065861783075,-0.2619266677946719,2.0335184987881214,-0.37984219227896826,0.23937792178355133,-0.7177615370892623,-0.06148029559266701,-0.06148029559266701,-0.7814856320202566,1.9760700997311131,0.7228043903765459,0.4481994586006217,-0.06148029559266701,0.2127025180887077,2.436706104734128,-0.005531837066441173,0.3447912610633156,0.18589586847145548,0.10467597056101892,1.386093528320324,1.638208714171853,0.07733177575208161,-0.6861725882485472,-0.32056824010222307,3.1296283127460667,-1.1115742979561345,1.4502485272895491,0.7953385242734627,1.4714633126430223,0.18589586847145548,-0.2328390217993925,-0.2619266677946719,-0.9111757607706441,-1.0104720506565676,0.2659233011870234,0.07733177575208161,-0.1180065861783075,0.07733177575208161,0.31862879037972053,-0.2039047156366997,-0.350125356105606,-0.37984219227896826,1.8789142803170127,-0.4097204049195783,-0.7495318851344548,0.6492831048866388,-0.4097204049195783,0.10467597056101892,0.3447912610633156,1.4502485272895491,1.7799433878907398,0.15895673427969537,0.7712686001756313,0.07733177575208161,1.0303037635203478,-0.03343454335768025,-0.8136248100970255,0.2127025180887077,-0.6235310490678561,0.890558218300318,-0.4699677127277454,-0.1180065861783075,-0.08967050071108885,-0.654763070997487,0.37082842982646413,1.0532456836169948,0.2127025180887077,-0.2328390217993925,-0.4699677127277454,0.4481994586006217,-0.4097204049195783,0.9841240598522195,-0.4097204049195783,-1.3905052682383434,0.10467597056101892,-0.17512221304650355,0.18589586847145548,0.2127025180887077,-0.2619266677946719,0.39674143767950243,0.49917415125399284
| 2,702
|
Lysosomal lumen
| 22
| 32
| 3.970507
| 0.000072
|
P04062,Q14108,P07602,P50897,Q8NHP8,P15586,O14773,P16278,O00584,P61916,Q99538,Q13510,P38435,P11117,P10253,P10619,P54802,Q9NZJ7,P17900,Q8IV08,P06280,P06865
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
134,8,13,22,26,280,157,36,170,300,179,55,183,65,196,72,77,336,82,85,104,253
|
170,2685,157,531,134,817,104,253,13,675,523,343,196,72,65,1331,280,36,82,183,525,22,77,300,55,8,85,1482,26,179,1264,336
|
1.6117183489592206,-2.345009462881344,1.7166949344659548,0.5517730351345772,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,3.6358051961034,0.3483101035432623,0.5670274774060957,0.97311149261789,1.4795736761747307,2.469019679033845,2.5349567864503544,-0.16163385385214332,1.148975957368919,3.000210798187082,2.333654152549082,1.5521892607638046,0.5670274774060957,3.2708634537820394,2.4115869799105853,1.1090521543190752,2.6994624661868474,3.724959724908723,2.2841363418193175,-0.23437919882369965,3.224517506261788,1.5761067056736178,-0.10785697374131768,1.0006594538170546
| 2,702
|
Membrane lipid metabolic process
| 14
| 30
| 3.534068
| 0.000409
|
Q99805,P16278,P04062,P06280,O95470,Q96G23,P07602,Q8NBX0,P17900,P50897,Q13510,Q9P035,P06865,Q06136
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
251,36,134,104,107,301,13,112,82,22,55,312,253,189
|
495,1533,107,134,817,104,253,13,675,36,82,582,764,22,189,55,2614,1313,112,437,1625,301,1212,605,251,1165,909,336,312,1524
|
0.6124633021363719,-0.2712088850102407,2.0899995453915405,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,3.6358051961034,0.3483101035432623,3.000210798187082,2.333654152549082,0.4746659679952571,0.25102864836853117,3.2708634537820394,1.5160447795129783,2.6994624661868474,-1.307106361795847,-0.1436346549150024,2.0478703095158535,0.7459035635880372,-0.30834940175024095,1.1090521543190752,-0.07237000350541305,0.4434266881560912,1.2793186260964378,-0.03716952921365007,0.13467692383293534,1.0006594538170546,1.06873759915191,-0.2527554805154473
| 2,702
|
Organic acid transmembrane transport
| 11
| 29
| 3.392826
| 0.000692
|
P33527,O43772,Q9H2H9,Q9Y619,P41440,Q9UBX3,Q9H2D1,P08183,P53985,Q9BQT8,P23786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
352,162,198,351,271,109,51,84,244,93,63
|
162,989,942,966,1170,84,1329,539,63,1086,365,1576,352,271,803,244,1020,1312,2231,809,508,93,51,198,1133,109,645,812,351
|
1.6820076128894363,0.0667537675442864,0.10084869034597146,0.08383480077369695,-0.05473421435229654,2.3040194739784066,-0.16163385385214332,0.536463418458696,2.5721316468788222,-0.0022514235063176217,0.9174606497851514,-0.2897399955466822,0.9453792994602913,1.188515758083854,0.2181049920661174,1.2921274336650987,0.04960511328482398,-0.1436346549150024,-0.6574202145206469,0.2181049920661174,0.5973722597638846,2.2440618128355347,2.822658973915516,1.4795736761747307,-0.019675434888960938,2.0899995453915405,0.39613357596639254,0.2181049920661174,0.9592685631657338
| 2,702
|
Sphingolipid metabolism
| 13
| 24
| 3.38767
| 0.000705
|
P51648,A0FGR8,P16278,P04062,P10619,P06280,O95470,Q96G23,P07602,P17900,Q13510,P06865,Q06136
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
256,317,36,134,72,104,107,301,13,82,55,253,189
|
317,495,1533,531,1642,107,134,104,253,13,675,72,36,82,582,256,189,55,2614,301,1107,1165,336,1524
|
1.0416407333608675,0.6124633021363719,-0.2712088850102407,0.5517730351345772,-0.3270376997249967,2.0899995453915405,1.90774847949041,2.1316806866838474,1.2664695220524946,3.6358051961034,0.3483101035432623,2.469019679033845,3.000210798187082,2.333654152549082,0.4746659679952571,1.2535798932893194,1.5160447795129783,2.6994624661868474,-1.307106361795847,1.1090521543190752,-0.0022514235063176217,-0.03716952921365007,1.0006594538170546,-0.2527554805154473
| 2,702
|
Sphingolipid metabolic process
| 13
| 25
| 3.387378
| 0.000706
|
Q99805,P16278,P04062,P06280,O95470,Q96G23,P07602,P17900,P50897,Q13510,Q9P035,P06865,Q06136
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
251,36,134,104,107,301,13,82,22,55,312,253,189
|
495,1533,107,134,104,253,13,675,36,82,582,764,22,189,55,2614,1313,437,301,251,1165,909,336,312,1524
|
0.6124633021363719,-0.2712088850102407,2.0899995453915405,1.90774847949041,2.1316806866838474,1.2664695220524946,3.6358051961034,0.3483101035432623,3.000210798187082,2.333654152549082,0.4746659679952571,0.25102864836853117,3.2708634537820394,1.5160447795129783,2.6994624661868474,-1.307106361795847,-0.1436346549150024,0.7459035635880372,1.1090521543190752,1.2793186260964378,-0.03716952921365007,0.13467692383293534,1.0006594538170546,1.06873759915191,-0.2527554805154473
| 2,702
|
Organic anion transmembrane transporter activity
| 16
| 31
| 3.368243
| 0.000756
|
P33527,Q6NUK1,P11166,O15439,Q9H2H9,O00400,P41440,Q9UBX3,Q9HC21,P12236,Q9H2D1,P53985,Q8TB61,Q96QD8,Q9BQT8,Q9Y619
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
352,419,539,422,198,264,271,109,432,457,51,244,152,508,93,351
|
264,422,736,989,966,856,1329,539,779,457,352,271,244,1020,1312,419,1514,152,809,508,558,93,51,198,1133,432,109,645,812,351,840
|
1.2146655480675908,0.7749899149252996,0.28370179506564897,0.0667537675442864,0.08383480077369695,0.1682421911682641,-0.16163385385214332,0.536463418458696,0.2345983492140732,0.701892290350493,0.9453792994602913,1.188515758083854,1.2921274336650987,0.04960511328482398,-0.1436346549150024,0.7894576895397357,-0.2527554805154473,1.7738458790955642,0.2181049920661174,0.5973722597638846,0.5210982679469837,2.2440618128355347,2.822658973915516,1.4795736761747307,-0.019675434888960938,0.7604719773481496,2.0899995453915405,0.39613357596639254,0.2181049920661174,0.9592685631657338,0.20154814096271612
| 2,702
|
SLC superfamily of solute carriers
| 25
| 43
| 3.363664
| 0.000769
|
Q70HW3,O00400,Q9BXP2,P41440,Q8TB61,Q6NUK1,O43772,P11166,Q6NT16,Q9HC21,Q9H2D1,Q9H2H9,Q9Y6C9,Q9NZJ7,Q8IXU6,P12236,Q9H2V7,Q9BQT8,Q9Y619,Q8NEW0,P04920,Q9UBX3,O95202,P53985,Q96QD8
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
5,264,528,271,152,419,162,539,44,432,51,198,332,336,79,457,346,93,351,96,484,109,241,244,508
|
264,162,736,989,241,966,484,856,1329,539,779,457,271,244,1122,1020,1312,2109,44,419,1514,5,79,96,152,809,508,558,93,528,657,51,198,346,1133,432,336,109,645,812,351,332,840
|
1.2146655480675908,1.6820076128894363,0.28370179506564897,0.0667537675442864,1.3048961711518003,0.08383480077369695,0.6424844207170954,0.1682421911682641,-0.16163385385214332,0.536463418458696,0.2345983492140732,0.701892290350493,1.188515758083854,1.2921274336650987,-0.019675434888960938,0.04960511328482398,-0.1436346549150024,-0.5774483420396528,2.88278106126926,0.7894576895397357,-0.2527554805154473,3.857928935292173,2.382546224088504,2.223868499779184,1.7738458790955642,0.2181049920661174,0.5973722597638846,0.5210982679469837,2.2440618128355347,0.5670274774060957,0.38025187320722004,2.822658973915516,1.4795736761747307,0.97311149261789,-0.019675434888960938,0.7604719773481496,1.0006594538170546,2.0899995453915405,0.39613357596639254,0.2181049920661174,0.9592685631657338,1.0143650321652233,0.20154814096271612
| 2,702
|
Anion transmembrane transport
| 19
| 41
| 3.305816
| 0.000947
|
P41440,P21796,P45880,Q8TB61,O15439,Q9UHG3,Q9HC21,Q9H2D1,P51790,P12236,P08183,Q9BQT8,Q9Y619,P33527,P04920,Q9Y277,Q9UBX3,P53985,P51798
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
271,15,16,152,422,43,432,51,185,457,84,93,351,352,484,232,109,244,248
|
422,736,989,942,966,484,856,1170,84,1329,779,457,15,352,271,16,803,185,248,244,1122,1020,1312,730,152,2231,809,93,528,51,1133,432,733,109,43,645,232,812,1009,351,840
|
0.7749899149252996,0.28370179506564897,0.0667537675442864,0.10084869034597146,0.08383480077369695,0.6424844207170954,0.1682421911682641,-0.05473421435229654,2.3040194739784066,-0.16163385385214332,0.2345983492140732,0.701892290350493,3.558604191488058,0.9453792994602913,1.188515758083854,3.515789489534347,0.2181049920661174,1.5281289711930328,1.2793186260964378,1.2921274336650987,-0.019675434888960938,0.04960511328482398,-0.1436346549150024,0.2999454932185619,1.7738458790955642,-0.6574202145206469,0.2181049920661174,2.2440618128355347,0.5670274774060957,2.822658973915516,-0.019675434888960938,0.7604719773481496,0.2999454932185619,2.0899995453915405,2.8912919988892094,0.39613357596639254,1.3429641997032904,0.2181049920661174,0.0667537675442864,0.9592685631657338,0.20154814096271612
| 2,702
|
Lysosome
| 24
| 45
| 3.271723
| 0.001069
|
P04062,Q14108,P07602,P50897,P15586,O14773,P16278,Q9Y487,Q93050,P61916,Q99538,Q13510,P11117,P10253,O15118,P10619,P54802,Q9NZJ7,P17900,P08236,P11279,P06280,O75503,P06865
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
134,8,13,22,280,157,36,37,40,300,179,55,65,196,69,72,77,336,82,343,221,104,247,253
|
1031,2685,2482,157,69,531,1746,247,134,817,104,253,13,675,343,1037,795,196,72,65,221,373,280,36,82,662,525,22,77,592,300,2053,1688,55,8,501,437,1657,40,179,625,336,1112,588,37
|
0.03238835570877815,-2.345009462881344,-0.9490913261043828,1.7166949344659548,2.497417369060405,0.5517730351345772,-0.3835820044684915,1.2793186260964378,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,3.6358051961034,0.3483101035432623,0.97311149261789,0.03238835570877815,0.2181049920661174,1.4795736761747307,2.469019679033845,2.5349567864503544,1.3806795740768194,0.8893532800594045,1.148975957368919,3.000210798187082,2.333654152549082,0.36431084877418707,0.5670274774060957,3.2708634537820394,2.4115869799105853,0.4590750194134483,1.1090521543190752,-0.5379930941294808,-0.3458054921469844,2.6994624661868474,3.724959724908723,0.6124633021363719,0.7459035635880372,-0.3270376997249967,2.941956184280774,1.5761067056736178,0.42772059381643684,1.0006594538170546,-0.0022514235063176217,0.4746659679952571,2.975355597745126
| 2,702
|
Sterol metabolic process
| 16
| 32
| 3.243295
| 0.001182
|
O75477,P16435,O15118,P04062,Q8WTV0,Q16850,Q9BQE5,Q14534,Q15392,Q14739,P48449,P37268,O94905,Q6P1A2,Q15800,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,258,69,134,202,139,12,173,142,235,242,147,180,212,283,153
|
69,192,1427,180,2529,134,1459,694,258,2345,147,525,2321,242,860,1876,300,1932,2225,2520,173,235,2228,142,1963,283,139,212,202,12,153,1564
|
2.497417369060405,1.4917673289663298,-0.21607946299314143,1.5641657435116996,-1.0359996897457213,1.90774847949041,-0.23437919882369965,0.33224923450336813,1.240649509692531,-0.7801186405050577,1.7964787566429434,0.5670274774060957,-0.759434892091634,1.3048961711518003,0.1682421911682641,-0.44085843678176667,1.1090521543190752,-0.46011623230476806,-0.6574202145206469,-1.0141164567184937,1.5998828218041645,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.8413617509235753,1.4056301198534875,1.4550755191396691,3.642742245523358,1.7510836692846126,-0.2712088850102407
| 2,702
|
Steroid binding
| 13
| 20
| 3.211773
| 0.001319
|
O75477,O15118,P04062,Q14108,P61916,P21796,P45880,O00264,O94905,O15173,Q9H4L5,P30536,P38435
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,69,134,8,300,15,16,243,180,83,310,151,183
|
243,69,83,192,180,134,363,1828,15,582,1794,151,183,16,300,8,834,1735,2332,310
|
1.2921274336650987,2.497417369060405,2.3040194739784066,1.4917673289663298,1.5641657435116996,1.90774847949041,0.9174606497851514,-0.4216838952161537,3.558604191488058,0.4746659679952571,-0.4025919634436768,1.7738458790955642,1.5521892607638046,3.515789489534347,1.1090521543190752,3.724959724908723,0.20154814096271612,-0.3646533883592373,-0.759434892091634,1.0822196248016487
| 2,702
|
Molecular transducer activity
| 7
| 29
| 3.209228
| 0.001331
|
Q15629,Q99720,O15118,Q14108,Q5KU26,O15173,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,3,69,8,106,83,151
|
1976,941,69,83,2039,1170,1604,373,662,151,1335,1064,766,631,1069,1044,8,64,1312,731,106,1287,202,2148,3,409,854,636,1668
|
-0.4988841983587244,0.10084869034597146,2.497417369060405,2.3040194739784066,-0.5379930941294808,-0.05473421435229654,-0.30834940175024095,0.8893532800594045,0.36431084877418707,1.7738458790955642,-0.16163385385214332,0.015103007549675692,0.25102864836853117,0.411956352337547,0.015103007549675692,0.03238835570877815,3.724959724908723,2.5628717612311127,-0.1436346549150024,0.2999454932185619,2.100461504027298,-0.1257092085342695,1.4550755191396691,-0.5973075767254589,3.979807696470662,0.8182439888074761,0.18492735557866916,0.411956352337547,-0.3270376997249967
| 2,702
|
Secondary active transmembrane transporter activity
| 12
| 22
| 3.136551
| 0.001709
|
P04920,Q9H2H9,O00400,Q96ES6,P41440,Q9UBX3,P12236,O95202,P53985,P51790,P51798,Q96QD8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
484,198,264,169,271,109,457,241,244,185,248,508
|
264,241,484,856,1329,779,457,271,185,248,244,1122,1020,1312,697,169,508,528,198,109,812,840
|
1.2146655480675908,1.3048961711518003,0.6424844207170954,0.1682421911682641,-0.16163385385214332,0.2345983492140732,0.701892290350493,1.188515758083854,1.5281289711930328,1.2793186260964378,1.2921274336650987,-0.019675434888960938,0.04960511328482398,-0.1436346549150024,0.33224923450336813,1.6235191019297979,0.5973722597638846,0.5670274774060957,1.4795736761747307,2.0899995453915405,0.2181049920661174,0.20154814096271612
| 2,702
|
Receptor
| 14
| 25
| 3.130865
| 0.001743
|
Q9UQB8,P57105,Q9Y639,Q14108,Q8WTV0,Q13641,Q9NR77,Q9BUN8,Q13432,P11717,Q8WUM4,A6NIH7,O75381,Q567V2
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
68,452,487,8,202,268,115,409,62,373,507,28,319,126
|
28,1706,1746,319,2158,1643,1170,373,662,452,1069,62,268,8,126,518,202,507,409,1266,115,2154,1451,68,487
|
3.193293290882018,-0.3646533883592373,-0.3835820044684915,1.0416407333608675,-0.6172554898593413,-0.3270376997249967,-0.05473421435229654,0.8893532800594045,0.36431084877418707,0.7166140404526318,0.015103007549675692,2.581369142815388,1.2016115002763685,3.724959724908723,1.9513955835040788,0.5822271013569861,1.4550755191396691,0.5973722597638846,0.8182439888074761,-0.10785697374131768,2.015974080477711,-0.5973075767254589,-0.21607946299314143,2.525606359287873,0.6424844207170954
| 2,702
|
Receptor
| 15
| 33
| 3.116578
| 0.00183
|
Q9NS69,P02786,Q99720,O15118,P35613,Q14108,P24390,Q8WTV0,Q5KU26,Q14739,O00264,O15173,Q9Y5M8,P11717,P11279
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
0,322,3,69,229,8,10,202,106,235,243,83,121,373,221
|
243,1976,941,69,83,322,1170,674,2371,2010,1228,1604,221,373,2536,662,10,229,2518,1044,8,235,1312,106,202,2148,415,3,0,1668,1270,121,2659
|
1.2921274336650987,-0.4988841983587244,0.10084869034597146,2.497417369060405,2.3040194739784066,1.028025369515471,-0.05473421435229654,0.3483101035432623,-0.8008978009850447,-0.51839569402218,-0.09007741527544748,-0.30834940175024095,1.3806795740768194,0.8893532800594045,-1.0579885203161268,0.36431084877418707,3.6703575558394306,1.3429641997032904,-1.0141164567184937,0.03238835570877815,3.724959724908723,1.3303143323167068,-0.1436346549150024,2.100461504027298,1.4550755191396691,-0.5973075767254589,0.8038756116143992,3.979807696470662,4.339098672789817,-0.3270376997249967,-0.10785697374131768,1.9730395335085762,-1.6700298575117414
| 2,702
|
Intrinsic component of mitochondrial inner membrane
| 15
| 30
| 3.113629
| 0.001848
|
O14925,Q99595,Q6P4A7,Q9H3K2,Q13505,Q16891,Q15070,Q16134,Q9HC21,Q5XKP0,Q9BUR5,Q9Y2R0,Q9NX63,O75431,Q6UXV4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
160,1,259,391,42,493,110,333,432,371,276,21,341,252,413
|
160,252,497,966,857,2539,1122,42,110,333,493,1313,371,259,413,697,2270,809,1,276,391,1133,658,432,872,341,628,21,660,690
|
1.7051658996048906,1.2664695220524946,0.6124633021363719,0.08383480077369695,0.1682421911682641,-1.0579885203161268,-0.019675434888960938,2.9082562157141907,2.079509582008797,1.0006594538170546,0.6275005747563835,-0.1436346549150024,0.9034306979462009,1.240649509692531,0.8038756116143992,0.33224923450336813,-0.6979483260765379,0.2181049920661174,4.023672847582024,1.1753780817167876,0.8610548868787217,-0.019675434888960938,0.38025187320722004,0.7604719773481496,0.1682421911682641,0.9869083646757261,0.42772059381643684,3.2938193341266992,0.38025187320722004,0.3483101035432623
| 2,702
|
Inorganic anion transport
| 16
| 27
| 3.106187
| 0.001895
|
P33527,P04920,O15439,Q9Y277,Q9BXP2,Q9UHG3,Q9UBX3,P21796,P45880,Q9H0H5,P08183,Q9C0H2,P30536,O43681,P51790,P51798
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
352,484,422,232,528,43,109,15,16,239,84,20,151,531,185,248
|
2036,422,531,484,84,15,151,352,16,185,248,574,1122,1020,730,2109,2231,1052,528,20,239,109,43,232,812,2460,840
|
-0.5379930941294808,0.7749899149252996,0.5517730351345772,0.6424844207170954,2.3040194739784066,3.558604191488058,1.7738458790955642,0.9453792994602913,3.515789489534347,1.5281289711930328,1.2793186260964378,0.4901999107033141,-0.019675434888960938,0.04960511328482398,0.2999454932185619,-0.5774483420396528,-0.6574202145206469,0.03238835570877815,0.5670274774060957,3.3618378249093492,1.3176250631188255,2.0899995453915405,2.8912919988892094,1.3429641997032904,0.2181049920661174,-0.9062528889503797,0.20154814096271612
| 2,702
|
Lytic vacuole organization
| 7
| 18
| 3.101244
| 0.001927
|
P11117,P10253,P04062,Q14108,P54802,P50897,O14773
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,196,134,8,77,22,157
|
1031,157,247,134,675,196,65,532,22,1336,77,973,1095,8,1348,1211,689,1424
|
0.03238835570877815,1.7166949344659548,1.2793186260964378,1.90774847949041,0.3483101035432623,1.4795736761747307,2.5349567864503544,0.5517730351345772,3.2708634537820394,-0.16163385385214332,2.4115869799105853,0.08383480077369695,-0.0022514235063176217,3.724959724908723,-0.16163385385214332,-0.07237000350541305,0.3483101035432623,-0.19785570229010588
| 2,702
|
Slc mediated transmembrane transport
| 12
| 22
| 3.07567
| 0.0021
|
Q8NEW0,P11166,Q70HW3,Q9H2H9,P04920,O00400,P35613,Q9UBX3,P12236,P53985,Q8TB61,Q96QD8
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
96,539,5,198,484,264,229,109,457,244,152,508
|
264,484,856,1329,539,779,457,1608,229,970,244,1312,1514,5,96,152,508,558,198,109,812,840
|
1.2146655480675908,0.6424844207170954,0.1682421911682641,-0.16163385385214332,0.536463418458696,0.2345983492140732,0.701892290350493,-0.30834940175024095,1.3429641997032904,0.08383480077369695,1.2921274336650987,-0.1436346549150024,-0.2527554805154473,3.857928935292173,2.223868499779184,1.7738458790955642,0.5973722597638846,0.5210982679469837,1.4795736761747307,2.0899995453915405,0.2181049920661174,0.20154814096271612
| 2,702
|
Proton transmembrane transporter activity
| 15
| 34
| 3.073135
| 0.002118
|
P56385,Q9Y487,O00400,Q96ES6,Q93050,O95202,Q13423,P00403,P20674,Q7KZN9,P13073,O75964,P51790,Q9UDW1,P24539
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
475,37,264,169,40,241,50,114,405,213,337,117,185,90,374
|
264,2070,117,241,114,856,818,1036,1250,779,337,405,472,2320,374,969,921,748,1577,1927,2469,185,642,475,592,1122,50,213,40,169,90,1112,37,734
|
1.2146655480675908,-0.5576770803133537,1.9838171226896273,1.3048961711518003,2.015974080477711,0.1682421911682641,0.20154814096271612,0.03238835570877815,-0.10785697374131768,0.2345983492140732,0.9869083646757261,0.8182439888074761,0.672293189318447,-0.759434892091634,0.8893532800594045,0.08383480077369695,0.11779590878562075,0.2673963211845321,-0.2897399955466822,-0.46011623230476806,-0.9276215217752557,1.5281289711930328,0.39613357596639254,0.672293189318447,0.4590750194134483,-0.019675434888960938,2.831306853338417,1.4056301198534875,2.941956184280774,1.6235191019297979,2.254119276071687,-0.0022514235063176217,2.975355597745126,0.2999454932185619
| 2,702
|
Carboxylic acid transport
| 10
| 30
| 3.072043
| 0.002126
|
P33527,Q9H2H9,P41440,Q9NZJ7,P07602,Q9UBX3,Q9H2D1,P53985,Q9BQT8,Q9Y619
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
352,198,271,336,13,109,51,244,93,351
|
422,989,942,966,894,1170,13,1329,2465,1085,1086,352,271,803,244,1020,1312,1514,2231,809,508,93,51,198,1133,336,109,645,812,351
|
0.7749899149252996,0.0667537675442864,0.10084869034597146,0.08383480077369695,0.13467692383293534,-0.05473421435229654,3.6358051961034,-0.16163385385214332,-0.9276215217752557,-0.0022514235063176217,-0.0022514235063176217,0.9453792994602913,1.188515758083854,0.2181049920661174,1.2921274336650987,0.04960511328482398,-0.1436346549150024,-0.2527554805154473,-0.6574202145206469,0.2181049920661174,0.5973722597638846,2.2440618128355347,2.822658973915516,1.4795736761747307,-0.019675434888960938,1.0006594538170546,2.0899995453915405,0.39613357596639254,0.2181049920661174,0.9592685631657338
| 2,702
|
Active ion transmembrane transporter activity
| 22
| 43
| 3.028899
| 0.002454
|
O00400,P41440,P20674,O15439,Q96ES6,P16615,Q9HD20,P51790,Q9H2H9,P12236,Q7KZN9,P13073,Q9UDW1,P21281,P33527,P04920,P05023,O95202,P98194,P00403,P51798,Q96QD8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
264,271,405,422,169,292,56,185,198,457,213,337,90,472,352,484,363,241,369,114,248,508
|
264,422,241,114,484,363,1457,856,818,1329,1036,1250,779,457,337,292,737,405,472,2320,707,921,352,1577,1927,271,185,248,592,369,1122,1020,213,169,508,528,198,56,90,1112,812,734,840
|
1.2146655480675908,0.7749899149252996,1.3048961711518003,2.015974080477711,0.6424844207170954,0.9174606497851514,-0.23437919882369965,0.1682421911682641,0.20154814096271612,-0.16163385385214332,0.03238835570877815,-0.10785697374131768,0.2345983492140732,0.701892290350493,0.9869083646757261,1.122403168752099,0.28370179506564897,0.8182439888074761,0.672293189318447,-0.759434892091634,0.31612783470675104,0.11779590878562075,0.9453792994602913,-0.2897399955466822,-0.46011623230476806,1.188515758083854,1.5281289711930328,1.2793186260964378,0.4590750194134483,0.9034306979462009,-0.019675434888960938,0.04960511328482398,1.4056301198534875,1.6235191019297979,0.5973722597638846,0.5670274774060957,1.4795736761747307,2.690507421713021,2.254119276071687,-0.0022514235063176217,0.2181049920661174,0.2999454932185619,0.20154814096271612
| 2,702
|
Organic acid transmembrane transporter activity
| 10
| 21
| 3.023307
| 0.0025
|
P33527,Q9H2H9,O15439,P41440,Q9UBX3,P08183,Q9H2D1,P53985,Q9BQT8,Q9Y619
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
352,198,422,271,109,84,51,244,93,351
|
422,989,966,84,1329,352,271,244,1020,1312,1514,809,508,93,51,198,1133,109,645,812,351
|
0.7749899149252996,0.0667537675442864,0.08383480077369695,2.3040194739784066,-0.16163385385214332,0.9453792994602913,1.188515758083854,1.2921274336650987,0.04960511328482398,-0.1436346549150024,-0.2527554805154473,0.2181049920661174,0.5973722597638846,2.2440618128355347,2.822658973915516,1.4795736761747307,-0.019675434888960938,2.0899995453915405,0.39613357596639254,0.2181049920661174,0.9592685631657338
| 2,702
|
Subsets and Splits
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