term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Negative regulation of notch4 signaling
| 17
| 39
| 2.213416
| 0.026869
|
P20618,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1028,935,1758,2604,2752,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.2705818269915089,0.3225058562487884,-0.01588339248816641,-0.35651011446187664,-0.4354630136619837,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Peptidase complex
| 22
| 61
| 2.212949
| 0.026901
|
Q9Y6J9,P28070,Q99436,O43396,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9UMX0,P60900,P62333,Q96ES7,P62191,Q15008
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
412,10,275,14,19,645,649,36,287,44,528,416,415,677,183,63,632,602,482,251,364,368
|
528,2480,1339,677,1342,1668,14,1141,415,3336,1147,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2366,2789,1748,1617,645,1751,602,1371,1095,364,649,482,3367,1621,1758,2604,36,3243,368,1172,2859,795,3022,1257,251,1520,275,1124,1205,759,632,1793,1592,1537,412
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,3.8679292480336267,0.21860961070595744,0.6588880680272334,-1.6357045003570223,0.21860961070595744,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.25144761327768334,-0.4618111582937517,-0.01588339248816641,0.03631578405272416,0.4779963367555763,-0.01588339248816641,0.5038712950051047,0.14055920679442668,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-1.9872712604203693,0.03631578405272416,-0.01588339248816641,-0.35651011446187664,2.341547868171487,-1.0987950297512232,0.7104735093783054,0.21860961070595744,-0.5145541510399857,0.4003032120537953,-0.6466903057401047,0.19260518741836744,0.9420920779153221,0.08846302330909535,0.890692731740149,0.24460179084386904,0.21860961070595744,0.4262123823488152,0.5038712950051047,-0.01588339248816641,0.062395840059970745,0.08846302330909535,0.6846861232304023
| 3,437
|
Formation of the early elongation complex
| 7
| 21
| 2.206462
| 0.027352
|
P19388,P19447,Q92759,Q8WX92,P13984,P18615,P18074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,193,175,213,171,18,150
|
1725,529,171,150,18,1229,160,193,1681,1897,2164,234,975,1368,2696,2301,1623,550,213,175,1204
|
-0.01588339248816641,0.5555875994245117,1.0960533169755888,1.1729039116516042,3.1951985716164666,0.19260518741836744,1.1216796679268493,1.0447718492501796,0.010222744193719364,-0.06813541787919085,-0.17280182112563378,0.9677767865553218,0.2965498167601974,0.14055920679442668,-0.40913022679566735,-0.22521818684495445,0.03631578405272416,0.5555875994245117,1.0191166070744402,1.0960533169755888,0.21860961070595744
| 3,437
|
Signaling by notch4
| 18
| 43
| 2.198579
| 0.027908
|
P20618,Q04721,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,689,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1028,935,689,1758,1759,2604,2248,2752,368,3231,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.2705818269915089,0.3225058562487884,0.4521100613445833,-0.01588339248816641,-0.01588339248816641,-0.35651011446187664,-0.19900296686591165,-0.4354630136619837,0.7104735093783054,-1.0453909009683404,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Nucleophile aminohydrolases, N-terminal [IPR029055]
| 6
| 18
| 2.192466
| 0.028346
|
P20618,P28070,Q99436,P28072,P49721,P49720
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
63,10,275,44,19,183
|
1342,1350,63,2162,1085,416,1357,1088,10,44,287,183,19,602,652,1238,2796,275
|
0.14055920679442668,0.14055920679442668,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,1.070417398184814,3.09516261931888,0.5038712950051047,0.4779963367555763,0.19260518741836744,-0.4618111582937517,0.890692731740149
| 3,437
|
Proteasome degradation
| 18
| 44
| 2.189126
| 0.028588
|
P20618,Q9UL46,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P01889,P49720,O75832,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
63,759,602,287,10,275,44,482,528,416,19,148,183,415,364,645,368,649
|
528,2480,1339,1342,1668,415,148,3089,1883,890,721,3205,831,63,1355,2162,1085,416,1357,1088,10,44,287,1422,1611,2237,2435,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.14055920679442668,0.010222744193719364,0.6588880680272334,1.1729039116516042,-0.7526829888195903,-0.06813541787919085,0.3484500400782194,0.4262123823488152,-0.9653888365499469,0.37438246142501497,1.759396490717528,0.14055920679442668,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.1145174430622166,0.03631578405272416,-0.19900296686591165,-0.27769138081303274,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Protein polyubiquitination
| 12
| 54
| 2.184138
| 0.028952
|
Q8NEZ5,P19474,Q9BW61,Q9C0C9,Q9UBS8,P55786,Q9H000,Q9Y263,Q96FW1,Q14669,Q96J02,O95155
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
261,206,100,407,73,45,17,29,23,209,157,153
|
2218,1484,1598,153,1738,206,1552,2688,1819,642,2435,685,45,838,647,935,936,1621,2053,604,2752,1628,1440,2178,1103,209,1172,740,2860,2062,908,850,1928,261,23,157,3291,100,407,17,1526,3395,73,2209,869,1335,2081,3200,2211,560,1474,2139,29,411
|
-0.19900296686591165,0.08846302330909535,0.03631578405272416,1.1472965125647505,-0.01588339248816641,1.0191166070744402,0.062395840059970745,-0.40913022679566735,-0.042002740889055014,0.4779963367555763,-0.27769138081303274,0.4521100613445833,2.0383249778341375,0.37438246142501497,0.4779963367555763,0.3225058562487884,0.3225058562487884,0.03631578405272416,-0.12044123528532528,0.5038712950051047,-0.4354630136619837,0.03631578405272416,0.1145174430622166,-0.17280182112563378,0.24460179084386904,1.0191166070744402,0.21860961070595744,0.4262123823488152,-0.5145541510399857,-0.12044123528532528,0.3484500400782194,0.37438246142501497,-0.06813541787919085,0.9163974154088532,2.8195382437120737,1.1472965125647505,-1.2861333763187535,1.402955118769559,0.6846861232304023,3.2451792675084628,0.08846302330909535,-2.4497606170123416,1.6577255052032591,-0.17280182112563378,0.37438246142501497,0.16658842023685425,-0.12044123528532528,-0.9387496993351647,-0.17280182112563378,0.5555875994245117,0.1145174430622166,-0.14661461977842807,2.54311235991026,0.6846861232304023
| 3,437
|
Regulation of proteasomal protein catabolic process
| 16
| 76
| 2.159763
| 0.030791
|
Q9BTA9,Q8NEZ5,Q9BW61,O43765,Q9NZL4,Q9UBS8,Q9Y4X5,Q4ZIN3,Q9H000,O00560,Q8IXJ6,Q92990,P62191,P78559,Q06787,O15372
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,261,100,7,178,73,411,425,17,146,50,283,364,245,184,158
|
677,146,1343,1479,1728,158,7,1484,415,1956,2421,889,3333,1603,2155,3050,2786,831,2160,1611,2237,601,1686,1427,2912,973,731,2984,977,1748,1617,1751,1027,838,1095,364,649,482,1908,1301,245,1163,902,1758,184,1916,425,3316,2612,50,2257,261,1707,283,1194,620,752,2828,1,100,1201,2831,17,2528,178,2269,73,1533,2137,759,560,632,2139,411,1074,1537
|
0.4521100613445833,1.1729039116516042,0.14055920679442668,0.08846302330909535,-0.01588339248816641,1.1216796679268493,5.471572567824065,0.08846302330909535,0.6588880680272334,-0.09428154235373645,-0.27769138081303274,0.3484500400782194,-1.5817900434130296,0.03631578405272416,-0.17280182112563378,-0.6996557465222012,-0.4618111582937517,0.37438246142501497,-0.17280182112563378,0.03631578405272416,-0.19900296686591165,0.5038712950051047,0.010222744193719364,0.1145174430622166,-0.5673604973578883,0.2965498167601974,0.4262123823488152,-0.6202311111444645,0.2965498167601974,-0.01588339248816641,0.03631578405272416,-0.01588339248816641,0.2705818269915089,0.37438246142501497,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.06813541787919085,0.16658842023685425,0.9420920779153221,0.21860961070595744,0.3484500400782194,-0.01588339248816641,1.070417398184814,-0.06813541787919085,0.6588880680272334,-1.4203362219262978,-0.35651011446187664,1.9370073166859738,-0.19900296686591165,0.9163974154088532,0.010222744193719364,0.8649779587240712,0.21860961070595744,0.5038712950051047,0.4262123823488152,-0.4881748174530137,12.741750894706325,1.402955118769559,0.21860961070595744,-0.4881748174530137,3.2451792675084628,-0.3039496266010951,1.0960533169755888,-0.19900296686591165,1.6577255052032591,0.08846302330909535,-0.14661461977842807,0.4262123823488152,0.5555875994245117,0.5038712950051047,-0.14661461977842807,0.6846861232304023,0.2705818269915089,0.08846302330909535
| 3,437
|
Pten regulation
| 27
| 72
| 2.156478
| 0.031046
|
P28070,Q99436,Q13547,Q15382,P49721,Q15022,P55036,P62195,Q14997,P28074,Q14781,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P31751,Q86YP4,Q9UL46,P27361,P28482,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,511,139,19,789,645,649,36,287,786,44,528,416,415,677,183,63,323,851,759,99,477,602,482,364,368
|
528,2480,1339,677,1342,1668,2631,2148,415,1547,1599,2540,1738,831,1813,63,2162,1085,416,1357,99,1088,10,44,287,477,323,1611,2943,2237,2435,2101,183,19,2789,645,602,1095,364,649,482,1373,2302,1758,2440,2604,1693,511,786,1629,36,368,789,139,2755,1631,1042,851,1639,2193,2571,1194,275,1124,1651,2527,2403,1007,759,2139,1793,1868
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,-0.3828126439803247,-0.17280182112563378,0.6588880680272334,0.062395840059970745,0.03631578405272416,-0.3302224903627467,-0.01588339248816641,0.37438246142501497,-0.042002740889055014,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,1.402955118769559,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.6072596412110887,0.78777240802752,0.03631578405272416,-0.5937877925087558,-0.19900296686591165,-0.27769138081303274,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.14055920679442668,-0.22521818684495445,-0.01588339248816641,-0.27769138081303274,-0.35651011446187664,0.010222744193719364,0.5814291122334218,0.4003032120537953,0.03631578405272416,2.341547868171487,0.7104735093783054,0.4003032120537953,1.1985019251998819,-0.4354630136619837,0.03631578405272416,0.2705818269915089,0.37438246142501497,0.03631578405272416,-0.17280182112563378,-0.3302224903627467,0.21860961070595744,0.890692731740149,0.24460179084386904,0.03631578405272416,-0.3039496266010951,-0.25144761327768334,0.2965498167601974,0.4262123823488152,-0.14661461977842807,-0.01588339248816641,-0.042002740889055014
| 3,437
|
Transcription elongation from rna polymerase ii promoter
| 7
| 32
| 2.147407
| 0.031761
|
O14776,P19447,Q92541,Q8WX92,P13984,P18615,Q14241
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,193,142,213,171,18,208
|
1725,2,1283,171,18,193,1819,234,1495,3074,2746,3120,208,1244,1916,2755,2859,1106,742,2758,659,745,550,375,1847,213,142,998,2009,1204,707,877
|
-0.01588339248816641,11.465227444473113,0.16658842023685425,1.0960533169755888,3.1951985716164666,1.0447718492501796,-0.042002740889055014,0.9677767865553218,0.08846302330909535,-0.7261617112368798,-0.4354630136619837,-0.7792194448781685,1.0191166070744402,0.19260518741836744,-0.06813541787919085,-0.4354630136619837,-0.5145541510399857,0.24460179084386904,0.4262123823488152,-0.4354630136619837,0.4779963367555763,0.4262123823488152,0.5555875994245117,0.7104735093783054,-0.042002740889055014,1.0191166070744402,1.1985019251998819,0.2965498167601974,-0.09428154235373645,0.21860961070595744,0.4521100613445833,0.37438246142501497
| 3,437
|
Protein k63 linked ubiquitination
| 8
| 15
| 2.135968
| 0.032682
|
P19474,P61088,Q9C0C9,Q9Y263,Q96FW1,Q14669,Q96J02,Q9ULT8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
206,647,407,29,23,209,157,560
|
2218,1598,1738,206,2435,647,209,740,23,157,407,560,1474,2139,29
|
-0.19900296686591165,0.03631578405272416,-0.01588339248816641,1.0191166070744402,-0.27769138081303274,0.4779963367555763,1.0191166070744402,0.4262123823488152,2.8195382437120737,1.1472965125647505,0.6846861232304023,0.5555875994245117,0.1145174430622166,-0.14661461977842807,2.54311235991026
| 3,437
|
Runx1 regulates transcription of genes involved in differentiation of hscs
| 19
| 43
| 2.133423
| 0.03289
|
P28070,Q99436,P49721,Q96J02,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,157,645,649,36,287,44,528,416,415,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,1668,415,3205,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,3181,2992,3144,1758,2604,2178,36,368,157,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,-0.9653888365499469,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.912124863937556,-0.6202311111444645,-0.8323373668559508,-0.01588339248816641,-0.35651011446187664,-0.17280182112563378,2.341547868171487,0.7104735093783054,1.1472965125647505,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Hedgehog ligand biogenesis
| 18
| 41
| 2.133186
| 0.032909
|
P20618,Q14997,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,36,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,415,2976,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,1751,602,1095,364,649,482,3328,1758,2604,36,368,275,1124,2675,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,-0.6202311111444645,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,-0.01588339248816641,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-1.5279234016007261,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,-0.3828126439803247,0.4262123823488152,-0.01588339248816641
| 3,437
|
Mrna capping
| 6
| 19
| 2.122924
| 0.03376
|
P19388,P19447,Q92759,P13984,O60942,P18074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,193,175,171,147,150
|
1725,529,1541,147,171,150,1229,160,193,1681,1897,2164,234,975,1368,2696,2301,1623,175
|
-0.01588339248816641,0.5555875994245117,0.062395840059970745,1.1729039116516042,1.0960533169755888,1.1729039116516042,0.19260518741836744,1.1216796679268493,1.0447718492501796,0.010222744193719364,-0.06813541787919085,-0.17280182112563378,0.9677767865553218,0.2965498167601974,0.14055920679442668,-0.40913022679566735,-0.22521818684495445,0.03631578405272416,1.0960533169755888
| 3,437
|
Tcf dependent signaling in response to wnt
| 24
| 65
| 2.108143
| 0.035019
|
P28070,Q99436,Q13547,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q14738,P31751,Q9UL46,P60900,P30154,P62333,P62191,Q13363,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,511,19,645,649,36,287,44,528,416,415,677,183,63,692,323,759,602,232,482,364,124,368
|
528,2480,1339,677,762,1342,1479,1668,415,3205,831,1813,63,2161,2162,1085,416,1357,1088,10,44,287,1683,232,323,1819,1611,2817,2237,2101,2912,183,19,731,2560,2789,645,602,1095,364,649,482,3181,1028,1373,2302,2992,1758,2604,124,511,1628,692,36,368,3033,2758,1847,275,1124,1206,1946,759,1793,2779
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.4003032120537953,0.14055920679442668,0.08846302330909535,0.010222744193719364,0.6588880680272334,-0.9653888365499469,0.37438246142501497,-0.042002740889055014,1.759396490717528,-0.17280182112563378,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.010222744193719364,0.9677767865553218,0.78777240802752,-0.042002740889055014,0.03631578405272416,-0.4881748174530137,-0.19900296686591165,-0.14661461977842807,-0.5673604973578883,1.070417398184814,3.09516261931888,0.4262123823488152,-0.3302224903627467,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.912124863937556,0.2705818269915089,0.14055920679442668,-0.22521818684495445,-0.6202311111444645,-0.01588339248816641,-0.35651011446187664,1.2496700320630116,0.5814291122334218,0.03631578405272416,0.4521100613445833,2.341547868171487,0.7104735093783054,-0.6731652315486031,-0.4354630136619837,-0.042002740889055014,0.890692731740149,0.24460179084386904,0.21860961070595744,-0.06813541787919085,0.4262123823488152,-0.01588339248816641,-0.4354630136619837
| 3,437
|
Neddylation
| 28
| 77
| 2.106995
| 0.035118
|
Q8NEZ5,Q86VX2,P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,Q9UNS2,P28072,O00231,P25788,O75832,Q15369,P49720,P20618,Q99627,P61964,P61962,Q9NX08,Q9BW61,P60900,P62333,Q13309,Q9UBW8,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
261,141,10,275,19,645,649,36,287,442,44,528,416,415,303,183,63,463,576,451,630,100,602,482,604,255,364,368
|
528,2480,1339,677,1342,1668,926,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1094,2297,1095,451,576,364,649,482,935,1758,1989,2604,604,1240,2752,3017,1628,2054,1034,36,1037,368,3033,1311,303,1916,2792,1631,1998,1254,141,1111,261,2922,1642,1324,1579,275,1124,463,1125,100,1941,3066,630,1659,255,759,1793,442,1074
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.3225058562487884,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,-0.22521818684495445,0.24460179084386904,0.6330792667297674,0.5297350212533344,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.09428154235373645,-0.35651011446187664,0.5038712950051047,0.19260518741836744,-0.4354630136619837,-0.6466903057401047,0.03631578405272416,-0.12044123528532528,0.2705818269915089,2.341547868171487,0.2705818269915089,0.7104735093783054,-0.6731652315486031,0.16658842023685425,0.8135178673565373,-0.06813541787919085,-0.4618111582937517,0.03631578405272416,-0.09428154235373645,0.19260518741836744,1.1985019251998819,0.24460179084386904,0.9163974154088532,-0.5673604973578883,0.03631578405272416,0.16658842023685425,0.062395840059970745,0.890692731740149,0.24460179084386904,0.6330792667297674,0.24460179084386904,1.402955118769559,-0.06813541787919085,-0.6996557465222012,0.5038712950051047,0.03631578405272416,0.9420920779153221,0.4262123823488152,-0.01588339248816641,0.6588880680272334,0.2705818269915089
| 3,437
|
Actin polymerization or depolymerization
| 24
| 51
| 2.103818
| 0.035394
|
Q9NYL9,O00165,Q9UQB8,O60610,P07737,Q9NUQ9,Q9UHB6,Q01082,Q8N8S7,O15020,P58546,Q92747,P62993,O15144,Q7L576,O95429,Q9UEY8,P35241,Q14247,P50552,Q9UJU6,P59998,P47756,Q13813
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,256,13,765,30,297,441,782,583,300,197,461,687,566,326,74,497,352,844,235,383,480,727,605
|
256,300,566,2085,765,2344,2025,74,30,1148,352,1358,1610,2943,727,235,2041,3381,197,480,1300,1754,2370,687,2499,782,1987,1166,1834,1375,1765,605,2055,844,1445,3313,326,583,1456,461,913,956,297,134,497,441,383,13,2804,1273,2281
|
0.9163974154088532,0.8135178673565373,0.5297350212533344,-0.14661461977842807,0.4003032120537953,-0.25144761327768334,-0.12044123528532528,1.632286948462474,2.467578902400475,0.21860961070595744,0.736250302444436,0.14055920679442668,0.03631578405272416,-0.5937877925087558,0.4262123823488152,0.9677767865553218,-0.12044123528532528,-2.1501606682998604,1.0447718492501796,0.6072596412110887,0.16658842023685425,-0.01588339248816641,-0.25144761327768334,0.4521100613445833,-0.3039496266010951,0.4003032120537953,-0.09428154235373645,0.21860961070595744,-0.042002740889055014,0.14055920679442668,-0.01588339248816641,0.5038712950051047,-0.12044123528532528,0.37438246142501497,0.1145174430622166,-1.3934703658292524,0.78777240802752,0.5297350212533344,0.1145174430622166,0.6330792667297674,0.3484500400782194,0.3225058562487884,0.8392530272685477,1.2240906124858706,0.6072596412110887,0.6588880680272334,0.7104735093783054,4.239890873327849,-0.4618111582937517,0.19260518741836744,-0.19900296686591165
| 3,437
|
L1cam interactions
| 24
| 47
| 2.093897
| 0.036269
|
Q16512,O00560,P05556,Q9BUF5,Q01082,Q96S59,P63010,P51812,O15020,P15311,Q00610,P07942,Q12955,O94973,Q9BVA1,P26038,P27361,P35241,P28482,P06756,P04350,P50570,Q13813,P11047
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
657,146,891,437,782,46,779,57,300,683,688,569,81,825,357,832,99,352,477,718,475,837,605,117
|
146,300,825,1806,1808,475,891,718,569,1810,117,1888,1676,2093,683,1146,1813,832,99,477,352,2098,837,57,1158,2499,779,1373,1097,2302,688,782,1502,81,1375,3161,605,1443,3169,657,939,1118,1052,46,437,357,1214
|
1.1729039116516042,0.8135178673565373,0.37438246142501497,-0.042002740889055014,-0.042002740889055014,0.6072596412110887,0.3484500400782194,0.4262123823488152,0.5297350212533344,-0.042002740889055014,1.2752402417749096,-0.06813541787919085,0.010222744193719364,-0.14661461977842807,0.4521100613445833,0.21860961070595744,-0.042002740889055014,0.37438246142501497,1.402955118769559,0.6072596412110887,0.736250302444436,-0.14661461977842807,0.37438246142501497,1.8101826910064611,0.21860961070595744,-0.3039496266010951,0.4003032120537953,0.14055920679442668,0.24460179084386904,-0.22521818684495445,0.4521100613445833,0.4003032120537953,0.08846302330909535,1.5559205669344653,0.14055920679442668,-0.8589185757995703,0.5038712950051047,0.1145174430622166,-0.8855144491446009,0.4779963367555763,0.3225058562487884,0.24460179084386904,0.2705818269915089,2.0130072303019975,0.6588880680272334,0.736250302444436,0.21860961070595744
| 3,437
|
Positive regulation of dendritic spine development
| 7
| 12
| 2.093655
| 0.036291
|
Q9UQB8,Q9H2U1,Q9UJU6,P43034,Q14012,P61160,Q06787
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
13,755,383,600,606,736,184
|
600,736,1756,184,606,1242,1445,753,755,2406,383,13
|
0.5038712950051047,0.4262123823488152,-0.01588339248816641,1.070417398184814,0.5038712950051047,0.19260518741836744,0.1145174430622166,0.4262123823488152,0.4262123823488152,-0.25144761327768334,0.7104735093783054,4.239890873327849
| 3,437
|
Abnormal nipple morphology
| 12
| 64
| 2.084602
| 0.037105
|
Q9BTA9,Q9P2D1,P23786,P56589,P19447,Q15555,P10586,P18074,Q9NS87,P61978,Q13363,Q96EK5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,135,219,122,193,174,149,150,121,280,124,329
|
3108,1219,2631,2935,926,1283,2148,2090,1958,1420,3180,149,150,322,193,219,1966,1021,2942,1363,122,280,3160,737,979,1914,1166,124,1993,692,3209,1563,174,2755,1446,906,1697,1041,3097,2381,660,1512,1048,3175,486,663,1257,2517,329,1120,1,2773,999,2327,1204,2891,121,2132,135,1470,1211,3106,1070,2275
|
-0.7792194448781685,0.19260518741836744,-0.3828126439803247,-0.5937877925087558,0.3225058562487884,0.16658842023685425,-0.17280182112563378,-0.14661461977842807,-0.09428154235373645,0.1145174430622166,-0.912124863937556,1.1729039116516042,1.1729039116516042,0.78777240802752,1.0447718492501796,0.9934516077523754,-0.09428154235373645,0.2705818269915089,-0.5937877925087558,0.14055920679442668,1.2496700320630116,0.8649779587240712,-0.8589185757995703,0.4262123823488152,0.2965498167601974,-0.06813541787919085,0.21860961070595744,1.2496700320630116,-0.09428154235373645,0.4521100613445833,-0.9653888365499469,0.062395840059970745,1.0960533169755888,-0.4354630136619837,0.1145174430622166,0.3484500400782194,0.010222744193719364,0.2705818269915089,-0.7526829888195903,-0.25144761327768334,0.4779963367555763,0.08846302330909535,0.2705818269915089,-0.8855144491446009,0.6072596412110887,0.4779963367555763,0.19260518741836744,-0.3039496266010951,0.78777240802752,0.24460179084386904,12.741750894706325,-0.4354630136619837,0.2965498167601974,-0.22521818684495445,0.21860961070595744,-0.5409493221872759,1.2752402417749096,-0.14661461977842807,1.2240906124858706,0.1145174430622166,0.21860961070595744,-0.7526829888195903,0.2705818269915089,-0.19900296686591165
| 3,437
|
Transcription of the hiv genome
| 11
| 34
| 2.084098
| 0.037151
|
P19388,P19447,Q92759,Q8WX92,P13984,P18615,O60942,Q14241,P35269,P18074,Q92804
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,193,175,213,171,18,147,208,234,150,125
|
1725,529,1541,147,171,150,18,1229,160,193,3071,1681,2814,1897,2164,234,2366,1495,975,1368,3074,2696,2301,983,1623,208,303,1916,550,213,175,125,1204,877
|
-0.01588339248816641,0.5555875994245117,0.062395840059970745,1.1729039116516042,1.0960533169755888,1.1729039116516042,3.1951985716164666,0.19260518741836744,1.1216796679268493,1.0447718492501796,-0.7261617112368798,0.010222744193719364,-0.4881748174530137,-0.06813541787919085,-0.17280182112563378,0.9677767865553218,-0.25144761327768334,0.08846302330909535,0.2965498167601974,0.14055920679442668,-0.7261617112368798,-0.40913022679566735,-0.22521818684495445,0.2965498167601974,0.03631578405272416,1.0191166070744402,0.8135178673565373,-0.06813541787919085,0.5555875994245117,1.0191166070744402,1.0960533169755888,1.2496700320630116,0.21860961070595744,0.37438246142501497
| 3,437
|
Positive regulation of gtpase activity
| 7
| 45
| 2.067337
| 0.038702
|
P46108,Q8TEU7,Q9Y4G8,P31751,Q15555,Q66K14,Q12979
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
258,5,9,323,174,52,185
|
762,637,891,1889,2546,3094,323,2433,258,2363,731,1496,1370,1752,1301,353,185,2175,543,2856,1243,1105,174,2755,2380,52,2509,3173,1047,1320,5,1641,1646,622,1129,1001,558,1333,813,2211,1534,2277,9,2281,2725
|
0.4003032120537953,0.4779963367555763,0.3484500400782194,-0.06813541787919085,-0.3302224903627467,-0.7526829888195903,0.78777240802752,-0.27769138081303274,0.9163974154088532,-0.25144761327768334,0.4262123823488152,0.08846302330909535,0.14055920679442668,-0.01588339248816641,0.16658842023685425,0.736250302444436,1.070417398184814,-0.17280182112563378,0.5555875994245117,-0.5145541510399857,0.19260518741836744,0.24460179084386904,1.0960533169755888,-0.4354630136619837,-0.25144761327768334,1.9116583158985085,-0.3039496266010951,-0.8855144491446009,0.2705818269915089,0.16658842023685425,8.409153722165714,0.03631578405272416,0.03631578405272416,0.5038712950051047,0.24460179084386904,0.2965498167601974,0.5555875994245117,0.16658842023685425,0.4003032120537953,-0.17280182112563378,0.08846302330909535,-0.19900296686591165,5.02954103940884,-0.19900296686591165,-0.40913022679566735
| 3,437
|
Calponin homology domain [IPR001715]
| 15
| 27
| 2.060931
| 0.03931
|
Q99439,Q15417,Q8N3F8,Q01082,Q8NF91,Q15691,Q15555,O15020,Q14155,O43707,P46940,Q69YQ0,Q5M775,P12814,P46939
|
Sequence
|
InterPro Domain
|
interpro_domain
|
295,580,199,782,430,399,174,300,543,635,395,426,611,393,279
|
300,635,1412,393,1604,1680,1554,279,395,782,1031,1766,543,2179,1696,580,174,399,611,2061,426,1183,199,430,1458,295,871
|
0.8135178673565373,0.4779963367555763,0.1145174430622166,0.6846861232304023,0.03631578405272416,0.010222744193719364,0.062395840059970745,0.8649779587240712,0.6846861232304023,0.4003032120537953,0.2705818269915089,-0.01588339248816641,0.5555875994245117,-0.17280182112563378,0.010222744193719364,0.5297350212533344,1.0960533169755888,0.6846861232304023,0.5038712950051047,-0.12044123528532528,0.6588880680272334,0.21860961070595744,1.0447718492501796,0.6588880680272334,0.1145174430622166,0.8392530272685477,0.37438246142501497
| 3,437
|
CH domain superfamily [IPR036872]
| 15
| 27
| 2.060931
| 0.03931
|
Q99439,Q15417,Q8N3F8,Q01082,Q8NF91,Q15691,Q15555,O15020,Q14155,O43707,P46940,Q69YQ0,Q5M775,P12814,P46939
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
295,580,199,782,430,399,174,300,543,635,395,426,611,393,279
|
300,635,1412,393,1604,1680,1554,279,395,782,1031,1766,543,2179,1696,580,174,399,611,2061,426,1183,199,430,1458,295,871
|
0.8135178673565373,0.4779963367555763,0.1145174430622166,0.6846861232304023,0.03631578405272416,0.010222744193719364,0.062395840059970745,0.8649779587240712,0.6846861232304023,0.4003032120537953,0.2705818269915089,-0.01588339248816641,0.5555875994245117,-0.17280182112563378,0.010222744193719364,0.5297350212533344,1.0960533169755888,0.6846861232304023,0.5038712950051047,-0.12044123528532528,0.6588880680272334,0.21860961070595744,1.0447718492501796,0.6588880680272334,0.1145174430622166,0.8392530272685477,0.37438246142501497
| 3,437
|
Endothelium development
| 6
| 28
| 2.05758
| 0.03963
|
Q8TEU7,Q9Y4G8,Q9UDY2,O60869,O14974,P62820
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
5,9,179,319,318,113
|
318,2420,319,1013,683,969,572,832,1819,352,1358,2554,1428,1370,1981,1754,113,1373,1759,1622,510,5,2926,2867,179,9,2725,818
|
0.78777240802752,-0.27769138081303274,0.78777240802752,0.2705818269915089,0.4521100613445833,0.2965498167601974,0.5297350212533344,0.37438246142501497,-0.042002740889055014,0.736250302444436,0.14055920679442668,-0.3302224903627467,0.1145174430622166,0.14055920679442668,-0.09428154235373645,-0.01588339248816641,1.3008012987680424,0.14055920679442668,-0.01588339248816641,0.03631578405272416,0.5814291122334218,8.409153722165714,-0.5673604973578883,-0.5145541510399857,1.0960533169755888,5.02954103940884,-0.40913022679566735,0.4003032120537953
| 3,437
|
Microtubule family cytoskeletal protein
| 19
| 46
| 2.038181
| 0.041532
|
Q15691,Q9BSJ2,Q9BUF5,Q15555,O43663,Q96Q89,O43237,P52732,Q9NQT8,Q8WVJ2,Q9BVA1,Q9UH99,O00139,O43264,P04350,Q96CW5,P63167,Q9NS87,P78559
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
399,436,437,174,679,330,192,324,216,89,357,631,711,472,475,110,603,121,245
|
711,192,472,679,1805,2347,1806,475,1420,1677,1356,895,1025,324,1027,603,1097,245,1757,1763,3054,1308,1241,1695,1038,174,399,796,2707,89,110,2709,330,1711,436,2125,437,357,2126,216,121,868,631,2836,2336,1538
|
0.4262123823488152,1.0447718492501796,0.6072596412110887,0.4521100613445833,-0.042002740889055014,-0.25144761327768334,-0.042002740889055014,0.6072596412110887,0.1145174430622166,0.010222744193719364,0.14055920679442668,0.3484500400782194,0.2705818269915089,0.78777240802752,0.2705818269915089,0.5038712950051047,0.24460179084386904,0.9420920779153221,-0.01588339248816641,-0.01588339248816641,-0.6996557465222012,0.16658842023685425,0.19260518741836744,0.010222744193719364,0.2705818269915089,1.0960533169755888,0.6846861232304023,0.4003032120537953,-0.40913022679566735,1.504966893924838,1.3263532595041623,-0.40913022679566735,0.78777240802752,0.010222744193719364,0.6588880680272334,-0.14661461977842807,0.6588880680272334,0.736250302444436,-0.14661461977842807,1.0191166070744402,1.2752402417749096,0.37438246142501497,0.5038712950051047,-0.4881748174530137,-0.22521818684495445,0.08846302330909535
| 3,437
|
Response to epidermal growth factor
| 8
| 15
| 2.026395
| 0.042724
|
P27361,P28482,O95429,Q96A49,Q9UQB8,P33993,P19174,P46940
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,477,74,431,13,233,205,395
|
1284,74,533,205,2157,99,477,233,395,3286,1298,1914,1918,431,13
|
0.16658842023685425,1.632286948462474,0.5555875994245117,1.0191166070744402,-0.17280182112563378,1.402955118769559,0.6072596412110887,0.9677767865553218,0.6846861232304023,-1.2593312011384492,0.16658842023685425,-0.06813541787919085,-0.06813541787919085,0.6588880680272334,4.239890873327849
| 3,437
|
Importin-beta, N-terminal domain [IPR001494]
| 8
| 13
| 2.014943
| 0.043911
|
O15397,Q9HAV4,O00410,Q14974,Q9UIA9,O14787,O95373,Q92973
|
Sequence
|
InterPro Domain
|
interpro_domain
|
33,334,712,656,382,446,681,61
|
712,446,1479,33,1407,681,1749,656,855,61,1052,334,382
|
0.4262123823488152,0.6330792667297674,0.08846302330909535,2.4171879532917457,0.1145174430622166,0.4521100613445833,-0.01588339248816641,0.4779963367555763,0.37438246142501497,1.7847936603664607,0.2705818269915089,0.78777240802752,0.7104735093783054
| 3,437
|
Ncam signaling for neurite out growth
| 6
| 9
| 2.014175
| 0.043991
|
P27361,P62993,P28482,Q05397,Q13813,O15020
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
99,687,477,269,605,300
|
300,1676,2093,99,477,687,782,269,605
|
0.8135178673565373,0.010222744193719364,-0.14661461977842807,1.402955118769559,0.6072596412110887,0.4521100613445833,0.4003032120537953,0.890692731740149,0.5038712950051047
| 3,437
|
Negative regulation of mitotic cell cycle
| 12
| 58
| 2.008997
| 0.044537
|
Q9BTA9,Q15645,Q9NWV8,Q96BK5,O96017,O43264,P12270,O60566,Q96K76,P43246,Q96DY7,Q9BXW9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,545,439,166,320,472,533,414,551,151,250,227
|
2417,472,1596,1408,1219,414,717,2022,320,2540,927,533,893,2230,2160,2161,1970,1819,642,151,2636,1826,977,1978,1432,1098,1375,1167,1691,1240,1309,2856,2700,545,2755,941,942,2758,2451,1182,2456,166,250,750,2800,2710,551,3024,1,227,587,3270,867,439,1789,2269,2215,1538
|
-0.27769138081303274,0.6072596412110887,0.03631578405272416,0.1145174430622166,0.19260518741836744,0.6588880680272334,0.4262123823488152,-0.12044123528532528,0.78777240802752,-0.3302224903627467,0.3225058562487884,0.5555875994245117,0.3484500400782194,-0.19900296686591165,-0.17280182112563378,-0.17280182112563378,-0.09428154235373645,-0.042002740889055014,0.4779963367555763,1.1729039116516042,-0.3828126439803247,-0.042002740889055014,0.2965498167601974,-0.09428154235373645,0.1145174430622166,0.24460179084386904,0.14055920679442668,0.21860961070595744,0.010222744193719364,0.19260518741836744,0.16658842023685425,-0.5145541510399857,-0.40913022679566735,0.5555875994245117,-0.4354630136619837,0.3225058562487884,0.3225058562487884,-0.4354630136619837,-0.27769138081303274,0.21860961070595744,-0.27769138081303274,1.1216796679268493,0.9420920779153221,0.4262123823488152,-0.4618111582937517,-0.40913022679566735,0.5555875994245117,-0.6466903057401047,12.741750894706325,0.9934516077523754,0.5297350212533344,-1.1790031835723191,0.37438246142501497,0.6588880680272334,-0.01588339248816641,-0.19900296686591165,-0.17280182112563378,0.08846302330909535
| 3,437
|
Guanyl nucleotide exchange factor activity
| 7
| 38
| 2.008945
| 0.044543
|
Q8TEU7,Q9NR50,Q9Y4G8,Q13144,Q9HD47,A4D1U4,Q12979
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
5,101,9,155,78,264,185
|
264,1485,1889,2427,2095,1489,2233,730,3242,3218,2051,185,155,543,1171,2250,1835,1243,1042,341,1047,5,1050,486,622,999,1129,1001,3177,78,101,1267,1333,2584,1274,1868,1871,9
|
0.890692731740149,0.08846302330909535,-0.06813541787919085,-0.27769138081303274,-0.14661461977842807,0.08846302330909535,-0.19900296686591165,0.4262123823488152,-1.0987950297512232,-0.9920421587976711,-0.12044123528532528,1.070417398184814,1.1472965125647505,0.5555875994245117,0.21860961070595744,-0.19900296686591165,-0.042002740889055014,0.19260518741836744,0.2705818269915089,0.7620165773584887,0.2705818269915089,8.409153722165714,0.2705818269915089,0.6072596412110887,0.5038712950051047,0.2965498167601974,0.24460179084386904,0.2965498167601974,-0.8855144491446009,1.5813845281691368,1.402955118769559,0.19260518741836744,0.16658842023685425,-0.3302224903627467,0.19260518741836744,-0.042002740889055014,-0.042002740889055014,5.02954103940884
| 3,437
|
Centriolar satellite
| 7
| 24
| 1.990627
| 0.046522
|
Q15154,Q9UIS9,Q86UY6,Q8WXW3,Q00013,Q15398,Q03518
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
370,335,4,343,421,187,246
|
1542,1731,473,2286,3049,895,2553,977,421,246,1765,2442,370,187,2183,4,1927,2004,343,2265,335,872,633,1872
|
0.062395840059970745,-0.01588339248816641,0.6072596412110887,-0.22521818684495445,-0.6996557465222012,0.3484500400782194,-0.3302224903627467,0.2965498167601974,0.6588880680272334,0.9420920779153221,-0.01588339248816641,-0.27769138081303274,0.7104735093783054,1.070417398184814,-0.17280182112563378,9.799637345089687,-0.06813541787919085,-0.09428154235373645,0.7620165773584887,-0.19900296686591165,0.78777240802752,0.37438246142501497,0.5038712950051047,-0.042002740889055014
| 3,437
|
Physicochemical features and toxicityassociated pathways
| 10
| 18
| 1.985632
| 0.047074
|
P62993,P28482,Q14012,Q16512,Q05397,P07197,P07196,P61160,P07737,P19174
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
687,477,606,657,269,266,392,736,30,205
|
1013,392,266,30,1676,205,2161,477,1819,731,2600,736,1754,687,1502,269,606,657
|
0.2705818269915089,0.6846861232304023,0.890692731740149,2.467578902400475,0.010222744193719364,1.0191166070744402,-0.17280182112563378,0.6072596412110887,-0.042002740889055014,0.4262123823488152,-0.35651011446187664,0.4262123823488152,-0.01588339248816641,0.4521100613445833,0.08846302330909535,0.890692731740149,0.5038712950051047,0.4779963367555763
| 3,437
|
Ubiquitin-like domain superfamily [IPR029071]
| 28
| 48
| 1.978161
| 0.047911
|
Q9Y490,Q9Y4E8,Q04323,Q9Y4G8,O14562,Q05397,Q9Y5A7,Q96K76,O14641,P61960,Q9UNN5,Q96S82,P35240,Q96L92,Q86UV5,P15311,Q8NCF5,Q13625,Q99426,Q9BSL1,Q9BZL1,O00443,Q92575,P26038,Q9UMX0,P35241,Q9BZE9,Q5TDH0
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
1073,676,902,9,881,269,1074,551,762,396,561,294,773,860,427,683,853,938,331,464,467,564,619,832,632,352,105,907
|
564,881,762,2086,1962,683,832,773,352,1686,1748,1617,1370,1027,396,902,269,938,1916,1917,1836,907,427,853,1190,619,2073,551,860,294,1463,331,464,105,467,2528,3321,1533,632,561,2837,2721,1073,676,1871,3201,9,1074
|
0.5297350212533344,0.3484500400782194,0.4003032120537953,-0.14661461977842807,-0.09428154235373645,0.4521100613445833,0.37438246142501497,0.4003032120537953,0.736250302444436,0.010222744193719364,-0.01588339248816641,0.03631578405272416,0.14055920679442668,0.2705818269915089,0.6846861232304023,0.3484500400782194,0.890692731740149,0.3225058562487884,-0.06813541787919085,-0.06813541787919085,-0.042002740889055014,0.3484500400782194,0.6588880680272334,0.37438246142501497,0.21860961070595744,0.5038712950051047,-0.12044123528532528,0.5555875994245117,0.37438246142501497,0.8392530272685477,0.1145174430622166,0.78777240802752,0.6330792667297674,1.3774301147011645,0.6330792667297674,-0.3039496266010951,-1.447214540909255,0.08846302330909535,0.5038712950051047,0.5555875994245117,-0.4881748174530137,-0.40913022679566735,0.2705818269915089,0.4779963367555763,-0.042002740889055014,-0.9387496993351647,5.02954103940884,0.2705818269915089
| 3,437
|
Protein targeting to membrane
| 13
| 38
| 1.97706
| 0.048035
|
Q9H9H4,Q9UHB9,Q8N3F8,Q9UHD1,O43765,P31751,O60725,Q9GZY8,Q12955,O00560,Q15629,Q9NQG6,P56589
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
202,136,199,299,7,323,107,47,81,146,281,190,122
|
2590,146,1730,7,107,502,2290,532,3216,1423,323,972,1821,3409,1686,2559,122,1980,1372,2695,3013,81,1507,281,1927,199,2863,47,344,202,190,2964,1268,136,299,1951,1010,2018
|
-0.35651011446187664,1.1729039116516042,-0.01588339248816641,5.471572567824065,1.3518961797724143,0.5814291122334218,-0.22521818684495445,0.5555875994245117,-0.9920421587976711,0.1145174430622166,0.78777240802752,0.2965498167601974,-0.042002740889055014,-2.9700150109894183,0.010222744193719364,-0.3302224903627467,1.2496700320630116,-0.09428154235373645,0.14055920679442668,-0.40913022679566735,-0.6466903057401047,1.5559205669344653,0.08846302330909535,0.8649779587240712,-0.06813541787919085,1.0447718492501796,-0.5145541510399857,1.9876817318984872,0.7620165773584887,1.0447718492501796,1.070417398184814,-0.5937877925087558,0.19260518741836744,1.2240906124858706,0.8392530272685477,-0.06813541787919085,0.2965498167601974,-0.09428154235373645
| 3,437
|
Hiv transcription initiation
| 6
| 17
| 1.976987
| 0.048043
|
P19388,P19447,Q92759,P13984,P18074,Q92804
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,193,175,171,150,125
|
529,171,150,1229,160,193,1681,2814,1897,2164,234,2366,1368,2696,2301,175,125
|
0.5555875994245117,1.0960533169755888,1.1729039116516042,0.19260518741836744,1.1216796679268493,1.0447718492501796,0.010222744193719364,-0.4881748174530137,-0.06813541787919085,-0.17280182112563378,0.9677767865553218,-0.25144761327768334,0.14055920679442668,-0.40913022679566735,-0.22521818684495445,1.0960533169755888,1.2496700320630116
| 3,437
|
Positive regulation of proteolysis involved in cellular protein catabolic process
| 17
| 45
| 1.975726
| 0.048186
|
Q8NEZ5,Q9UMX0,Q9BW61,O43765,Q9NZL4,Q9UBS8,Q9Y4X5,Q4ZIN3,Q05397,P62333,Q9H000,Q8IXJ6,O75832,Q96HY6,P62191,Q9ULT8,Q06787
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
261,632,100,7,178,73,411,425,269,482,17,50,415,620,364,560,184
|
7,926,1484,415,889,3333,2155,831,1611,2237,601,1686,1427,2912,731,2984,977,2494,1751,364,649,482,1301,269,184,1916,425,3316,50,261,620,2710,100,1201,17,178,2269,73,1533,3136,560,632,2139,411,1074
|
5.471572567824065,0.3225058562487884,0.08846302330909535,0.6588880680272334,0.3484500400782194,-1.5817900434130296,-0.17280182112563378,0.37438246142501497,0.03631578405272416,-0.19900296686591165,0.5038712950051047,0.010222744193719364,0.1145174430622166,-0.5673604973578883,0.4262123823488152,-0.6202311111444645,0.2965498167601974,-0.3039496266010951,-0.01588339248816641,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.16658842023685425,0.890692731740149,1.070417398184814,-0.06813541787919085,0.6588880680272334,-1.4203362219262978,1.9370073166859738,0.9163974154088532,0.5038712950051047,-0.40913022679566735,1.402955118769559,0.21860961070595744,3.2451792675084628,1.0960533169755888,-0.19900296686591165,1.6577255052032591,0.08846302330909535,-0.8057709474338041,0.5555875994245117,0.5038712950051047,-0.14661461977842807,0.6846861232304023,0.2705818269915089
| 3,437
|
Tcell antigen receptor tcr pathway during staphylococcus aureus infection
| 10
| 14
| 1.97123
| 0.048698
|
Q15118,P27361,Q9UHD1,P62993,O43318,Q16512,P49841,P19174,O95433,O15111
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
579,99,299,687,883,657,731,205,826,27
|
27,883,826,892,205,99,2098,731,687,1502,1375,579,657,299
|
2.6185830710263986,0.3484500400782194,0.37438246142501497,0.3484500400782194,1.0191166070744402,1.402955118769559,-0.14661461977842807,0.4262123823488152,0.4521100613445833,0.08846302330909535,0.14055920679442668,0.5297350212533344,0.4779963367555763,0.8392530272685477
| 3,437
|
Regulation of actin cytoskeleton
| 21
| 42
| 1.960188
| 0.049974
|
Q9Y6W5,P46108,Q9UQB8,Q13464,Q05397,Q16512,P35580,P12814,P46940,P07737,O60610,Q14155,Q8N8S7,P15311,O14974,O00443,Q9UBI6,P26038,P27361,P35241,P28482
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
923,258,13,510,269,657,897,393,395,30,765,543,583,683,318,564,496,832,99,352,477
|
564,1278,318,765,1013,30,393,683,969,1148,2161,832,99,477,352,897,2098,1972,258,395,2169,1754,3160,2499,1502,269,1990,510,543,2250,657,583,2066,1456,1586,956,496,2211,13,2804,1273,923
|
0.5297350212533344,0.16658842023685425,0.78777240802752,0.4003032120537953,0.2705818269915089,2.467578902400475,0.6846861232304023,0.4521100613445833,0.2965498167601974,0.21860961070595744,-0.17280182112563378,0.37438246142501497,1.402955118769559,0.6072596412110887,0.736250302444436,0.3484500400782194,-0.14661461977842807,-0.09428154235373645,0.9163974154088532,0.6846861232304023,-0.17280182112563378,-0.01588339248816641,-0.8589185757995703,-0.3039496266010951,0.08846302330909535,0.890692731740149,-0.09428154235373645,0.5814291122334218,0.5555875994245117,-0.19900296686591165,0.4779963367555763,0.5297350212533344,-0.12044123528532528,0.1145174430622166,0.062395840059970745,0.3225058562487884,0.6072596412110887,-0.17280182112563378,4.239890873327849,-0.4618111582937517,0.19260518741836744,0.3484500400782194
| 3,437
|
transporter
| 17
| 60
| 3.357357
| 0.000787
|
O60518,Q567V2,O43772,Q8NFH4,Q9HD45,O60830,Q9Y619,Q96EE3,P41440,Q9H2V7,Q92544,Q99805,P53985,Q9H2D1,Q12769,Q99595,Q9UI26
|
Functions
|
Panther Protein class
|
panther_protein_class
|
279,89,2,275,346,13,47,416,20,93,322,387,25,58,335,29,161
|
547,2283,396,2003,1062,1136,1139,2286,2,279,985,13,1145,1917,651,2699,2701,20,2702,910,612,2826,1935,3379,25,3221,2406,999,1001,2320,335,2578,2877,572,89,3181,1668,2060,275,1485,586,322,944,416,2932,1803,29,387,3165,2847,58,93,1043,346,807,161,1412,1816,976,47
|
0.5325786056609498,-0.2617543886648669,0.6786577838997692,-0.14539417304951105,0.23556922766931127,0.19796354037843203,0.19796354037843203,-0.2617543886648669,7.749910293180719,0.8949511957915331,0.2730652157571057,4.700273968897019,0.19796354037843203,-0.10681568420881038,0.4589472845566754,-0.4577315218833705,-0.4577315218833705,3.868860485518748,-0.4577315218833705,0.31045289547876415,0.49581323527606314,-0.5368230072244451,-0.10681568420881038,-1.8529107405085548,3.625424116426576,-1.0194725501820754,-0.30074717415258867,0.2730652157571057,0.2730652157571057,-0.2617543886648669,0.7872171546294843,-0.379037955370512,-0.5765164870891749,0.5325786056609498,1.7638985489005425,-0.9380883363940782,0.008285488231352866,-0.14539417304951105,0.9306838219669343,0.08448395903578995,0.5325786056609498,0.8232188465018345,0.31045289547876415,0.6786577838997692,-0.6163076847411272,-0.029975155508291253,3.5641235813941115,0.7149376676487161,-0.8975352684516035,-0.5368230072244451,2.4921755075471337,1.6961201650403537,0.2730652157571057,0.7872171546294843,0.38490873941189513,1.248437636244502,0.1224203206127141,-0.029975155508291253,0.31045289547876415,2.8455158089159505
| 3,447
|
SLC superfamily of solute carriers
| 15
| 47
| 3.011984
| 0.002595
|
O43772,O95563,Q9Y6C9,Q9BSK2,Q9UBX3,P30825,Q9Y619,P41440,P53985,Q9H2D1,Q8IXU6,Q96H78,Q9H2V7,Q70HW3,Q5T1Q4
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
2,159,68,171,242,231,47,20,25,58,27,60,93,30,31
|
2607,2,1515,1912,2684,159,1345,2200,2912,1246,1153,231,20,3379,25,520,710,2572,1956,31,2055,3181,1960,2504,30,3182,2248,27,253,1023,60,679,2739,171,1493,2788,58,93,2789,2790,345,1125,242,3032,47,68,1718
|
-0.4183346979723081,7.749910293180719,0.046438768658526614,-0.10681568420881038,-0.4577315218833705,1.248437636244502,0.1224203206127141,-0.2228641911880681,-0.6163076847411272,0.16024710230774855,0.19796354037843203,1.0018867588079787,3.868860485518748,-1.8529107405085548,3.625424116426576,0.5692445891444328,0.4219795344352679,-0.379037955370512,-0.10681568420881038,3.502641907839727,-0.14539417304951105,-0.9380883363940782,-0.10681568420881038,-0.33984190680438486,3.53340553397087,-0.9380883363940782,-0.2228641911880681,3.625424116426576,0.9663286969491739,0.2730652157571057,2.459716473922899,0.4589472845566754,-0.4577315218833705,1.2134624234635654,0.08448395903578995,-0.4972278233176913,2.4921755075471337,1.6961201650403537,-0.4972278233176913,-0.4972278233176913,0.7872171546294843,0.23556922766931127,1.0018867588079787,-0.6961809613273137,2.8455158089159505,2.197913373742313,0.008285488231352866
| 3,447
|
Lipid biosynthesis
| 15
| 58
| 2.963985
| 0.003037
|
Q96G23,O75845,P35790,Q9HBU6,Q8IVS2,Q15185,Q15392,Q14739,Q9H3P7,Q9BY49,P27544,P38398,P53602,Q16850,P54646
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
36,187,6,71,40,358,42,202,344,213,50,232,181,119,95
|
693,981,3268,187,3041,758,1521,559,2015,50,6,2398,232,3373,1254,996,2023,1753,181,1754,95,3317,1548,1768,2235,202,3104,3179,358,42,2050,359,119,718,2879,790,40,1675,1196,1677,2065,2163,36,489,591,1307,213,344,2178,71,495,3066,1896,2531,742,2452,1053,1708
|
0.4219795344352679,0.2730652157571057,-1.142236601311283,1.1432690292803236,-0.7362619239858912,0.38490873941189513,0.046438768658526614,0.5325786056609498,-0.14539417304951105,2.7177993462966743,6.445508202017654,-0.30074717415258867,1.0018867588079787,-1.7680166991740838,0.16024710230774855,0.2730652157571057,-0.14539417304951105,-0.029975155508291253,1.1784064958234062,-0.029975155508291253,1.6621254486751404,-1.3486452779327809,0.046438768658526614,-0.029975155508291253,-0.2228641911880681,1.108049184762875,-0.816709764829542,-0.9380883363940782,0.7511237729781655,2.9723834308637342,-0.14539417304951105,0.7511237729781655,1.4566382478660667,0.4219795344352679,-0.5765164870891749,0.38490873941189513,3.0039705701207278,0.008285488231352866,0.19796354037843203,0.008285488231352866,-0.14539417304951105,-0.18407723239973067,3.3170860443680508,0.6058123542920794,0.5325786056609498,0.16024710230774855,1.0727461077752654,0.7872171546294843,-0.18407723239973067,2.1318529381716966,0.6058123542920794,-0.7362619239858912,-0.06834244752895141,-0.33984190680438486,0.4219795344352679,-0.30074717415258867,0.2730652157571057,0.008285488231352866
| 3,447
|
Meiotic cell cycle
| 23
| 61
| 2.890033
| 0.003852
|
Q15003,Q9Y2W6,Q08379,P49959,P35579,P42695,Q8N2A8,Q9NTJ3,Q9NQS7,Q9H6S0,P30153,Q08J23,P61160,O60921,Q9UQ84,Q9BZD4,Q12768,Q9H2V7,Q9UH99,O94901,P53350,Q9BTX1,Q15021
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
411,14,522,407,516,405,160,459,197,196,431,439,437,207,84,493,334,93,497,468,116,389,526
|
892,1137,2099,2609,1723,698,1605,207,1240,468,553,1343,1245,3356,2474,2763,2393,431,907,516,405,1534,407,708,116,2405,3012,437,1762,522,439,334,2233,2045,1774,1553,411,526,1656,788,1021,160,1392,1111,2071,2165,956,1207,389,681,493,93,196,2527,197,459,497,2671,84,1508,14
|
0.31045289547876415,0.19796354037843203,-0.18407723239973067,-0.4183346979723081,-0.029975155508291253,0.4219795344352679,0.008285488231352866,1.0727461077752654,0.16024710230774855,0.6058123542920794,0.5325786056609498,0.1224203206127141,0.16024710230774855,-1.5992385075338844,-0.33984190680438486,-0.4972278233176913,-0.30074717415258867,0.6422830455391815,0.31045289547876415,0.5692445891444328,0.6786577838997692,0.046438768658526614,0.6786577838997692,0.4219795344352679,1.4566382478660667,-0.30074717415258867,-0.6961809613273137,0.6422830455391815,-0.029975155508291253,0.5692445891444328,0.6422830455391815,0.7872171546294843,-0.2228641911880681,-0.14539417304951105,-0.029975155508291253,0.046438768658526614,0.6786577838997692,0.5692445891444328,0.008285488231352866,0.38490873941189513,0.2730652157571057,1.248437636244502,0.1224203206127141,0.23556922766931127,-0.14539417304951105,-0.18407723239973067,0.31045289547876415,0.19796354037843203,0.7149376676487161,0.4589472845566754,0.6058123542920794,1.6961201650403537,1.1432690292803236,-0.33984190680438486,1.1432690292803236,0.6422830455391815,0.6058123542920794,-0.4183346979723081,1.8650479272211853,0.08448395903578995,4.6710962008148424
| 3,447
|
Nonalcoholic fatty liver disease
| 11
| 55
| 2.409453
| 0.015976
|
O43676,P47985,P14406,P31930,P42574,P51970,P31751,Q86Y39,P13073,P54646,Q9Y6M9
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
64,66,8,200,76,166,144,238,266,95,163
|
1720,2903,3119,277,64,2680,2378,506,1610,551,2954,555,1342,1916,1831,827,2113,897,2201,1244,266,8,3324,1919,2472,1524,1248,1078,3073,1081,144,200,76,66,996,2564,166,1754,95,2487,1540,1847,2416,1765,1768,621,2644,3105,2717,238,952,957,2088,1707,163
|
-0.029975155508291253,-0.6163076847411272,-0.8570755720322065,0.8949511957915331,2.329294762925845,-0.4577315218833705,-0.30074717415258867,0.5692445891444328,0.008285488231352866,0.5325786056609498,-0.6561960301664904,0.5325786056609498,0.1224203206127141,-0.10681568420881038,-0.06834244752895141,0.3477336267234822,-0.18407723239973067,0.31045289547876415,-0.2228641911880681,0.16024710230774855,0.9306838219669343,5.867495109069628,-1.3901931269438366,-0.10681568420881038,-0.33984190680438486,0.046438768658526614,0.16024710230774855,0.23556922766931127,-0.7764383715343895,0.23556922766931127,1.3181491405527583,1.108049184762875,1.9989718320711238,2.2308503979159013,0.2730652157571057,-0.379037955370512,1.2134624234635654,-0.029975155508291253,1.6621254486751404,-0.33984190680438486,0.046438768658526614,-0.06834244752895141,-0.30074717415258867,-0.029975155508291253,-0.029975155508291253,0.49581323527606314,-0.4183346979723081,-0.816709764829542,-0.4577315218833705,1.0018867588079787,0.31045289547876415,0.31045289547876415,-0.14539417304951105,0.008285488231352866,1.248437636244502
| 3,447
|
Pten regulation
| 10
| 67
| 2.332258
| 0.019687
|
P46934,P28072,Q9UPQ9,Q14997,P49721,Q8IXK0,P49720,P31751,Q9HCE1,Q9Y2Q5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,35,176,74,11,273,137,144,21,156
|
2188,2901,3117,3038,2189,3192,1063,2543,2753,280,987,2686,2111,2957,1156,903,2018,2762,2817,1158,475,1743,766,35,767,3218,144,2623,704,3074,0,1845,137,11,2221,3076,1359,1941,2711,2137,2491,615,3156,1008,1948,1549,2145,481,1181,74,1014,1182,1664,3058,273,365,874,2736,2737,2894,21,1900,2670,1902,2671,176,156
|
-0.2228641911880681,-0.6163076847411272,-0.8570755720322065,-0.7362619239858912,-0.2228641911880681,-0.9787342650162025,0.23556922766931127,-0.379037955370512,-0.4972278233176913,0.8949511957915331,0.2730652157571057,-0.4577315218833705,-0.18407723239973067,-0.6561960301664904,0.19796354037843203,0.31045289547876415,-0.14539417304951105,-0.4972278233176913,-0.5368230072244451,0.19796354037843203,0.6058123542920794,-0.029975155508291253,0.38490873941189513,3.3170860443680508,0.38490873941189513,-1.0194725501820754,1.3181491405527583,-0.4183346979723081,0.4219795344352679,-0.7764383715343895,8.724440398807948,-0.06834244752895141,1.3528870084169071,5.276487554860215,-0.2228641911880681,-0.7764383715343895,0.1224203206127141,-0.10681568420881038,-0.4577315218833705,-0.18407723239973067,-0.33984190680438486,0.49581323527606314,-0.8975352684516035,0.2730652157571057,-0.10681568420881038,0.046438768658526614,-0.18407723239973067,0.6058123542920794,0.19796354037843203,2.0322884787072737,0.2730652157571057,0.19796354037843203,0.008285488231352866,-0.7362619239858912,0.9306838219669343,0.7511237729781655,0.3477336267234822,-0.4577315218833705,-0.4577315218833705,-0.5765164870891749,3.7474909960026888,-0.06834244752895141,-0.4183346979723081,-0.06834244752895141,-0.4183346979723081,1.2134624234635654,1.2833329435656124
| 3,447
|
Phospholipid metabolism
| 14
| 48
| 2.296256
| 0.021661
|
Q8N2A8,Q10713,P20339,P35790,Q9HBU6,Q8NCE2,P42356,Q9NPH0,Q9NQZ5,Q96T51,Q8IV08,Q8NCC3,Q96N66,Q8IY17
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,100,373,6,71,414,295,15,114,456,18,111,489,155
|
891,1513,1911,758,1156,373,6,1636,295,840,1254,2702,2023,2133,1360,615,1005,1175,100,1951,1372,1463,790,18,155,160,867,111,414,1196,3208,489,877,456,1579,3187,591,2662,3113,71,495,2445,15,114,2941,811,1053,2798
|
0.31045289547876415,0.046438768658526614,-0.10681568420881038,0.38490873941189513,0.19796354037843203,0.7149376676487161,6.445508202017654,0.008285488231352866,0.859129862238441,0.3477336267234822,0.16024710230774855,-0.4577315218833705,-0.14539417304951105,-0.18407723239973067,0.1224203206127141,0.49581323527606314,0.2730652157571057,0.19796354037843203,1.6280595211027935,-0.10681568420881038,0.1224203206127141,0.08448395903578995,0.38490873941189513,3.9292890997183534,1.2833329435656124,1.248437636244502,0.3477336267234822,1.4910703449620104,0.6786577838997692,0.19796354037843203,-0.9787342650162025,0.6058123542920794,0.3477336267234822,0.6422830455391815,0.046438768658526614,-0.9380883363940782,0.5325786056609498,-0.4183346979723081,-0.816709764829542,2.1318529381716966,0.6058123542920794,-0.30074717415258867,4.436348536801482,1.4910703449620104,-0.6163076847411272,0.38490873941189513,0.2730652157571057,-0.4972278233176913
| 3,447
|
Abnormality of the hypothalamus pituitary axis
| 29
| 73
| 2.234681
| 0.025438
|
O00170,Q8IY37,Q9NW13,Q07864,Q06787,Q9BXW9,Q8IY17,Q03164,P33991,P16435,Q4J6C6,P54277,P42356,Q8NI27,Q15233,O95714,O14654,Q7LG56,Q9H2P0,Q96LT9,Q93074,Q12768,Q8WWQ0,Q10713,P52701,O76024,Q15031,P38398,Q96GW9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
244,671,809,269,268,681,155,24,515,401,34,167,295,725,573,311,308,722,343,341,488,334,634,100,708,101,483,232,384
|
244,308,753,2099,1144,2807,101,311,2111,1152,2202,401,2392,2553,515,1253,2478,232,2869,1354,295,1925,2563,2311,1536,708,167,999,2028,2489,2410,2972,24,268,269,100,334,2575,1774,1269,2922,483,573,2335,1958,34,722,1872,2839,155,671,1793,725,634,488,2658,384,1885,341,1886,1304,681,878,343,1589,2366,1217,809,1504,1506,1595,2461,2859
|
0.9663286969491739,0.8232188465018345,0.38490873941189513,-0.18407723239973067,0.19796354037843203,-0.5368230072244451,1.5939217228877902,0.8232188465018345,-0.18407723239973067,0.19796354037843203,-0.2228641911880681,0.6786577838997692,-0.30074717415258867,-0.379037955370512,0.5692445891444328,0.16024710230774855,-0.33984190680438486,1.0018867588079787,-0.5765164870891749,0.1224203206127141,0.859129862238441,-0.10681568420881038,-0.379037955370512,-0.2617543886648669,0.046438768658526614,0.4219795344352679,1.2134624234635654,0.2730652157571057,-0.14539417304951105,-0.33984190680438486,-0.30074717415258867,-0.6561960301664904,3.6865458322344447,0.9306838219669343,0.9306838219669343,1.6280595211027935,0.7872171546294843,-0.379037955370512,-0.029975155508291253,0.16024710230774855,-0.6163076847411272,0.6058123542920794,0.5325786056609498,-0.2617543886648669,-0.10681568420881038,3.3791255969148795,0.4219795344352679,-0.06834244752895141,-0.5368230072244451,1.2833329435656124,0.4589472845566754,-0.029975155508291253,0.4219795344352679,0.49581323527606314,0.6058123542920794,-0.4183346979723081,0.7149376676487161,-0.06834244752895141,0.7872171546294843,-0.06834244752895141,0.16024710230774855,0.4589472845566754,0.3477336267234822,0.7872171546294843,0.046438768658526614,-0.2617543886648669,0.19796354037843203,0.38490873941189513,0.08448395903578995,0.08448395903578995,0.046438768658526614,-0.30074717415258867,-0.5368230072244451
| 3,447
|
Abnormality of the pituitary gland
| 26
| 68
| 2.223656
| 0.026172
|
O00170,Q8IY37,Q9NW13,Q07864,Q06787,Q8IY17,Q03164,P33991,P16435,Q4J6C6,P54277,P42356,Q8NI27,Q15233,O95714,O14654,Q7LG56,Q9H2P0,Q96LT9,Q93074,Q12768,Q8WWQ0,P52701,O76024,Q15031,Q96GW9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
244,671,809,269,268,155,24,515,401,34,167,295,725,573,311,308,722,343,341,488,334,634,708,101,483,384
|
244,308,753,1144,2807,101,311,2111,1152,2202,401,2392,2553,515,1253,2869,1354,295,1925,2563,2311,1536,708,167,999,2028,2489,2410,2972,24,268,269,334,2575,1774,1269,2922,483,573,2335,1958,34,722,1872,2839,155,671,1793,725,634,488,2658,384,1885,341,1886,1304,878,343,1589,2366,1217,809,1504,1506,1595,2461,2859
|
0.9663286969491739,0.8232188465018345,0.38490873941189513,0.19796354037843203,-0.5368230072244451,1.5939217228877902,0.8232188465018345,-0.18407723239973067,0.19796354037843203,-0.2228641911880681,0.6786577838997692,-0.30074717415258867,-0.379037955370512,0.5692445891444328,0.16024710230774855,-0.5765164870891749,0.1224203206127141,0.859129862238441,-0.10681568420881038,-0.379037955370512,-0.2617543886648669,0.046438768658526614,0.4219795344352679,1.2134624234635654,0.2730652157571057,-0.14539417304951105,-0.33984190680438486,-0.30074717415258867,-0.6561960301664904,3.6865458322344447,0.9306838219669343,0.9306838219669343,0.7872171546294843,-0.379037955370512,-0.029975155508291253,0.16024710230774855,-0.6163076847411272,0.6058123542920794,0.5325786056609498,-0.2617543886648669,-0.10681568420881038,3.3791255969148795,0.4219795344352679,-0.06834244752895141,-0.5368230072244451,1.2833329435656124,0.4589472845566754,-0.029975155508291253,0.4219795344352679,0.49581323527606314,0.6058123542920794,-0.4183346979723081,0.7149376676487161,-0.06834244752895141,0.7872171546294843,-0.06834244752895141,0.16024710230774855,0.3477336267234822,0.7872171546294843,0.046438768658526614,-0.2617543886648669,0.19796354037843203,0.38490873941189513,0.08448395903578995,0.08448395903578995,0.046438768658526614,-0.30074717415258867,-0.5368230072244451
| 3,447
|
Protein localization to mitochondrion
| 9
| 59
| 2.222276
| 0.026265
|
Q10713,Q9Y6C9,O00170,Q9NS69,Q9BZL1,O60830,Q15388,O95817,Q99595
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
100,68,244,9,172,13,270,59,29
|
244,980,466,3000,2606,1139,13,1824,1518,554,2685,1830,59,1520,2545,896,3372,3044,3198,1626,1156,2697,1634,769,2305,3011,2627,2131,296,2771,100,1768,572,270,2924,2424,1463,625,1281,793,673,487,29,1206,172,962,1982,1586,9,1049,2088,2532,2278,1509,3369,3354,1600,975,68
|
0.9663286969491739,0.2730652157571057,0.6058123542920794,-0.6961809613273137,-0.4183346979723081,0.19796354037843203,4.700273968897019,-0.06834244752895141,0.046438768658526614,0.5325786056609498,-0.4577315218833705,-0.06834244752895141,2.459716473922899,0.046438768658526614,-0.379037955370512,0.31045289547876415,-1.7680166991740838,-0.7362619239858912,-0.9787342650162025,0.008285488231352866,0.19796354037843203,-0.4577315218833705,0.008285488231352866,0.38490873941189513,-0.2617543886648669,-0.6961809613273137,-0.4183346979723081,-0.18407723239973067,0.859129862238441,-0.4972278233176913,1.6280595211027935,-0.029975155508291253,0.5325786056609498,0.9306838219669343,-0.6163076847411272,-0.30074717415258867,0.08448395903578995,0.49581323527606314,0.16024710230774855,0.38490873941189513,0.4589472845566754,0.6058123542920794,3.5641235813941115,0.19796354037843203,1.2134624234635654,0.31045289547876415,-0.10681568420881038,0.046438768658526614,5.475014480162415,0.2730652157571057,-0.14539417304951105,-0.33984190680438486,-0.2228641911880681,0.08448395903578995,-1.6834582174676083,-1.5153608569100934,0.046438768658526614,0.31045289547876415,2.197913373742313
| 3,447
|
mitochondria
| 6
| 11
| 2.190276
| 0.028504
|
Q9Y277,Q8IWA4,O95140,Q15388,P45880,P21796
|
Localization
|
OpenCell Localization
|
opencell_localization
|
368,583,554,270,85,281
|
1518,554,281,85,1773,270,583,728,1588,1499,368
|
0.046438768658526614,0.5325786056609498,0.8949511957915331,1.8313997395842538,-0.029975155508291253,0.9306838219669343,0.5325786056609498,0.4219795344352679,0.046438768658526614,0.08448395903578995,0.7511237729781655
| 3,447
|
Microtubule associated complex
| 23
| 52
| 2.137351
| 0.032569
|
P63167,Q02241,O95793,Q68CZ6,P49356,Q9UJW0,O00139,P29372,Q66K74,Q7Z4H7,Q14807,Q8NCM8,Q9NQS7,Q15555,O95235,O94927,P43034,Q15058,Q9BW19,Q8IVD9,Q96S59,P12270,Q9UKB1
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
249,616,509,272,655,162,395,404,578,448,661,321,197,442,310,428,190,82,492,486,640,353,128
|
395,892,1602,1423,2196,428,310,509,353,1633,404,1435,190,2561,995,997,655,2025,2408,249,616,1445,3204,1448,1265,1013,1267,661,82,442,2718,1959,578,272,448,486,321,1027,2729,2932,640,2587,492,1041,2081,197,1813,162,128,749,1419,1058
|
0.6786577838997692,0.31045289547876415,0.008285488231352866,0.08448395903578995,-0.2228641911880681,0.6422830455391815,0.8232188465018345,0.5692445891444328,0.7511237729781655,0.008285488231352866,0.6786577838997692,0.08448395903578995,1.1432690292803236,-0.379037955370512,0.2730652157571057,0.2730652157571057,0.4589472845566754,-0.14539417304951105,-0.30074717415258867,0.9663286969491739,0.49581323527606314,0.08448395903578995,-0.9787342650162025,0.08448395903578995,0.16024710230774855,0.2730652157571057,0.16024710230774855,0.4589472845566754,1.8650479272211853,0.6422830455391815,-0.4577315218833705,-0.10681568420881038,0.5325786056609498,0.9306838219669343,0.6422830455391815,0.6058123542920794,0.8232188465018345,0.2730652157571057,-0.4577315218833705,-0.6163076847411272,0.49581323527606314,-0.379037955370512,0.6058123542920794,0.2730652157571057,-0.14539417304951105,1.1432690292803236,-0.029975155508291253,1.248437636244502,1.4221308141162194,0.4219795344352679,0.1224203206127141,0.2730652157571057
| 3,447
|
SLC25 family of mitochondrial transporters
| 7
| 24
| 2.13518
| 0.032746
|
O43772,Q9Y6C9,Q9BSK2,Q9Y619,Q9H2D1,Q96H78,Q70HW3
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
2,68,171,47,58,60,30
|
2,1515,1912,1345,1246,1153,3379,710,2572,2055,1960,30,2248,60,2739,171,58,2789,345,1125,242,3032,47,68
|
7.749910293180719,0.046438768658526614,-0.10681568420881038,0.1224203206127141,0.16024710230774855,0.19796354037843203,-1.8529107405085548,0.4219795344352679,-0.379037955370512,-0.14539417304951105,-0.10681568420881038,3.53340553397087,-0.2228641911880681,2.459716473922899,-0.4577315218833705,1.2134624234635654,2.4921755075471337,-0.4972278233176913,0.7872171546294843,0.23556922766931127,1.0018867588079787,-0.6961809613273137,2.8455158089159505,2.197913373742313
| 3,447
|
Mitochondrial carrier domain superfamily [IPR023395]
| 7
| 24
| 2.13518
| 0.032746
|
O43772,Q9Y6C9,Q9BSK2,Q9Y619,Q9H2D1,Q96H78,Q70HW3
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
2,68,171,47,58,60,30
|
2,1515,1912,1345,1246,1153,3379,710,2572,2055,1960,30,2248,60,2739,171,58,2789,345,1125,242,3032,47,68
|
7.749910293180719,0.046438768658526614,-0.10681568420881038,0.1224203206127141,0.16024710230774855,0.19796354037843203,-1.8529107405085548,0.4219795344352679,-0.379037955370512,-0.14539417304951105,-0.10681568420881038,3.53340553397087,-0.2228641911880681,2.459716473922899,-0.4577315218833705,1.2134624234635654,2.4921755075471337,-0.4972278233176913,0.7872171546294843,0.23556922766931127,1.0018867588079787,-0.6961809613273137,2.8455158089159505,2.197913373742313
| 3,447
|
Mitochondrial substrate/solute carrier [IPR018108]
| 7
| 24
| 2.13518
| 0.032746
|
O43772,Q9Y6C9,Q9BSK2,Q9Y619,Q9H2D1,Q96H78,Q70HW3
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
2,68,171,47,58,60,30
|
2,1515,1912,1345,1246,1153,3379,710,2572,2055,1960,30,2248,60,2739,171,58,2789,345,1125,242,3032,47,68
|
7.749910293180719,0.046438768658526614,-0.10681568420881038,0.1224203206127141,0.16024710230774855,0.19796354037843203,-1.8529107405085548,0.4219795344352679,-0.379037955370512,-0.14539417304951105,-0.10681568420881038,3.53340553397087,-0.2228641911880681,2.459716473922899,-0.4577315218833705,1.2134624234635654,2.4921755075471337,-0.4972278233176913,0.7872171546294843,0.23556922766931127,1.0018867588079787,-0.6961809613273137,2.8455158089159505,2.197913373742313
| 3,447
|
Lysine acetylated histone binding
| 6
| 9
| 2.1342
| 0.032826
|
P25440,Q14997,Q86X55,P51532,Q03164,O43149
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
474,74,382,566,24,398
|
2375,398,474,566,24,74,382,634,806
|
-0.30074717415258867,0.6786577838997692,0.6058123542920794,0.5325786056609498,3.6865458322344447,2.0322884787072737,0.7149376676487161,0.49581323527606314,0.38490873941189513
| 3,447
|
Endopeptidase activity
| 11
| 68
| 2.124839
| 0.0336
|
Q10713,Q4J6C6,P28072,O94782,O75844,P49721,P42574,P49720,Q2T9J0,Q9BYT8,Q92643
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
100,34,35,188,38,11,76,137,152,195,193
|
3393,2194,1824,38,188,2292,2293,3045,1428,2205,903,1078,1158,766,35,767,2764,1160,2126,2869,76,1084,1926,773,137,11,911,2026,3201,2313,2487,1359,915,100,2974,2042,2045,1180,621,1462,152,34,625,2719,446,447,1101,791,363,2782,3300,193,1679,727,874,876,2263,2661,2736,1206,3187,195,1982,240,2274,747,1996,2676
|
-2.066593486448459,-0.2228641911880681,-0.06834244752895141,3.1611459359376193,1.1432690292803236,-0.2617543886648669,-0.2617543886648669,-0.7362619239858912,0.08448395903578995,-0.2228641911880681,0.31045289547876415,0.23556922766931127,0.19796354037843203,0.38490873941189513,3.3170860443680508,0.38490873941189513,-0.4972278233176913,0.19796354037843203,-0.18407723239973067,-0.5765164870891749,1.9989718320711238,0.23556922766931127,-0.10681568420881038,0.38490873941189513,1.3528870084169071,5.276487554860215,0.31045289547876415,-0.14539417304951105,-0.9787342650162025,-0.2617543886648669,-0.33984190680438486,0.1224203206127141,0.31045289547876415,1.6280595211027935,-0.6561960301664904,-0.14539417304951105,-0.14539417304951105,0.19796354037843203,0.49581323527606314,0.08448395903578995,1.2833329435656124,3.3791255969148795,0.49581323527606314,-0.4577315218833705,0.6422830455391815,0.6422830455391815,0.23556922766931127,0.38490873941189513,0.7511237729781655,-0.4972278233176913,-1.265814327992873,1.1432690292803236,0.008285488231352866,0.4219795344352679,0.3477336267234822,0.3477336267234822,-0.2228641911880681,-0.4183346979723081,-0.4577315218833705,0.19796354037843203,-0.9380883363940782,1.1432690292803236,-0.10681568420881038,1.0018867588079787,-0.2228641911880681,0.4219795344352679,-0.10681568420881038,-0.4183346979723081
| 3,447
|
Glycerophospholipid biosynthesis
| 6
| 28
| 2.118036
| 0.034172
|
P35790,Q9HBU6,Q9NQZ5,Q9NPH0,Q8IV08,Q8NCC3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
6,71,114,15,18,111
|
1513,1911,758,1156,6,1636,840,1254,2702,2023,2133,615,1463,790,18,160,111,1196,489,3187,591,3113,71,495,2445,15,114,1053
|
0.046438768658526614,-0.10681568420881038,0.38490873941189513,0.19796354037843203,6.445508202017654,0.008285488231352866,0.3477336267234822,0.16024710230774855,-0.4577315218833705,-0.14539417304951105,-0.18407723239973067,0.49581323527606314,0.08448395903578995,0.38490873941189513,3.9292890997183534,1.248437636244502,1.4910703449620104,0.19796354037843203,0.6058123542920794,-0.9380883363940782,0.5325786056609498,-0.816709764829542,2.1318529381716966,0.6058123542920794,-0.30074717415258867,4.436348536801482,1.4910703449620104,0.2730652157571057
| 3,447
|
Phosphorylation of the apc c
| 6
| 12
| 2.09025
| 0.036595
|
P53350,Q9UJX3,P30260,Q9H1A4,P14635,Q96DE5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
116,686,513,326,606,194
|
1621,606,513,116,1861,194,326,745,686,1899,1992,1594
|
0.008285488231352866,0.49581323527606314,0.5692445891444328,1.4566382478660667,-0.06834244752895141,1.1432690292803236,0.8232188465018345,0.4219795344352679,0.4589472845566754,-0.06834244752895141,-0.10681568420881038,0.046438768658526614
| 3,447
|
Rhythmic process
| 23
| 63
| 2.089071
| 0.036701
|
Q00839,P62136,Q9NZJ0,P63244,Q03164,Q14103,Q9BWF3,P43490,Q15233,P42574,Q93008,P78527,Q9H2P0,O95470,P54646,Q92769,O00429,Q9BQG0,Q13547,P04818,Q96NB3,Q9UKB1,Q13185
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
250,614,143,146,24,149,732,56,573,76,727,211,343,208,95,365,466,641,481,604,385,128,619
|
466,820,1135,2682,2683,895,2808,2810,208,2110,2111,604,1621,1350,1245,2298,1075,1920,1249,2820,704,76,56,95,3281,614,1541,146,211,919,250,24,1089,921,850,1768,2420,619,2145,481,149,573,1658,2717,1281,1021,2509,943,365,727,874,3246,385,1886,641,732,343,3297,143,128,1056,2537,1713
|
0.6058123542920794,0.3477336267234822,0.19796354037843203,-0.4577315218833705,-0.4577315218833705,0.31045289547876415,-0.5368230072244451,-0.5368230072244451,1.0727461077752654,-0.18407723239973067,-0.18407723239973067,0.49581323527606314,0.008285488231352866,0.1224203206127141,0.16024710230774855,-0.2617543886648669,0.23556922766931127,-0.10681568420881038,0.16024710230774855,-0.5368230072244451,0.4219795344352679,1.9989718320711238,2.589208534440012,1.6621254486751404,-1.1833394006713358,0.49581323527606314,0.046438768658526614,1.3181491405527583,1.0727461077752654,0.31045289547876415,0.9663286969491739,3.6865458322344447,0.23556922766931127,0.31045289547876415,0.3477336267234822,-0.029975155508291253,-0.30074717415258867,0.49581323527606314,-0.18407723239973067,0.6058123542920794,1.2833329435656124,0.5325786056609498,0.008285488231352866,-0.4577315218833705,0.16024710230774855,0.2730652157571057,-0.33984190680438486,0.31045289547876415,0.7511237729781655,0.4219795344352679,0.3477336267234822,-1.0603026943246578,0.7149376676487161,-0.06834244752895141,0.49581323527606314,0.4219795344352679,0.7872171546294843,-1.2245321317888591,1.3528870084169071,1.4221308141162194,0.2730652157571057,-0.33984190680438486,0.008285488231352866
| 3,447
|
Odontogenesis
| 6
| 10
| 2.088361
| 0.036765
|
P61586,Q92769,P35613,O95747,Q6P4Q7,Q13547
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,365,314,469,412,481
|
895,469,558,1840,1253,314,98,481,412,365
|
0.31045289547876415,0.6058123542920794,0.5325786056609498,-0.06834244752895141,0.16024710230774855,0.8232188465018345,1.6280595211027935,0.6058123542920794,0.6786577838997692,0.7511237729781655
| 3,447
|
Oxidase
| 7
| 20
| 2.086298
| 0.036952
|
O75845,O15260,Q709F0,P14406,Q15800,O43169,Q15067
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
187,37,236,8,359,49,150
|
2191,37,49,548,187,2288,1244,900,2692,8,1919,1524,1250,432,1931,150,359,863,236,2180
|
-0.2228641911880681,3.223667829266045,2.7498094128063153,0.5325786056609498,1.1432690292803236,-0.2617543886648669,0.16024710230774855,0.31045289547876415,-0.4577315218833705,5.867495109069628,-0.10681568420881038,0.046438768658526614,0.16024710230774855,0.6422830455391815,-0.10681568420881038,1.2833329435656124,0.7511237729781655,0.3477336267234822,1.0018867588079787,-0.18407723239973067
| 3,447
|
Organic acid transport
| 14
| 52
| 2.078259
| 0.037686
|
O43772,O95563,P08183,P28288,Q9UBX3,P30825,Q9Y619,P31751,P23786,P41440,P53985,Q9H2D1,Q96H78,P14174
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,159,218,313,242,231,47,144,294,20,25,58,60,94
|
3118,2607,2,1515,3039,1912,3234,159,1736,2471,2110,3290,1243,218,2200,2912,94,1431,294,313,231,144,2698,2209,20,332,3379,25,520,3282,3078,2572,1768,1458,622,1956,3272,2504,3182,3137,60,679,2739,58,2789,2790,2445,242,3032,746,3354,47
|
-0.8570755720322065,-0.4183346979723081,7.749910293180719,0.046438768658526614,-0.7362619239858912,-0.10681568420881038,-1.0603026943246578,1.248437636244502,-0.029975155508291253,-0.33984190680438486,-0.18407723239973067,-1.2245321317888591,0.16024710230774855,1.0373589279869617,-0.2228641911880681,-0.6163076847411272,1.6621254486751404,0.08448395903578995,0.859129862238441,0.8232188465018345,1.0018867588079787,1.3181491405527583,-0.4577315218833705,-0.2228641911880681,3.868860485518748,0.7872171546294843,-1.8529107405085548,3.625424116426576,0.5692445891444328,-1.1833394006713358,-0.7764383715343895,-0.379037955370512,-0.029975155508291253,0.08448395903578995,0.49581323527606314,-0.10681568420881038,-1.142236601311283,-0.33984190680438486,-0.9380883363940782,-0.8570755720322065,2.459716473922899,0.4589472845566754,-0.4577315218833705,2.4921755075471337,-0.4972278233176913,-0.4972278233176913,-0.30074717415258867,1.0018867588079787,-0.6961809613273137,0.4219795344352679,-1.5153608569100934,2.8455158089159505
| 3,447
|
Primary microcephaly
| 8
| 11
| 2.077131
| 0.03779
|
Q2VPK5,Q8NFH4,Q15003,Q15058,P42695,P35606,Q15021,Q86XL3
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
377,275,411,82,405,650,526,630
|
650,405,1844,711,411,526,82,377,630,275,2356
|
0.4589472845566754,0.6786577838997692,-0.06834244752895141,0.4219795344352679,0.6786577838997692,0.5692445891444328,1.8650479272211853,0.7149376676487161,0.49581323527606314,0.9306838219669343,-0.2617543886648669
| 3,447
|
Protein polyubiquitination
| 17
| 63
| 2.072622
| 0.038207
|
P46934,Q9NZJ0,Q9Y263,P55786,Q9UIQ6,Q7Z7E8,Q15386,Q99728,P38398,Q9C0C9,Q9H871,Q96PU5,P19474,P30260,Q9H1A4,Q9UKB1,O95155
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,143,349,296,45,413,623,590,232,458,684,22,607,513,326,128,217
|
3038,1511,1065,2106,217,2685,607,763,2764,513,1253,232,0,2026,296,1938,3202,2493,2771,1089,1765,3157,1648,3102,2039,782,2639,2042,3177,1012,1455,623,1861,2155,2337,2245,1281,413,3273,1575,952,22,590,3030,458,3064,326,684,1049,143,45,745,686,1899,1992,1594,128,1329,2093,1902,349,1997,2282
|
-0.7362619239858912,0.046438768658526614,0.23556922766931127,-0.18407723239973067,1.0373589279869617,-0.4577315218833705,0.49581323527606314,0.38490873941189513,-0.4972278233176913,0.5692445891444328,0.16024710230774855,1.0018867588079787,8.724440398807948,-0.14539417304951105,0.859129862238441,-0.10681568420881038,-0.9787342650162025,-0.33984190680438486,-0.4972278233176913,0.23556922766931127,-0.029975155508291253,-0.8975352684516035,0.008285488231352866,-0.816709764829542,-0.14539417304951105,0.38490873941189513,-0.4183346979723081,-0.14539417304951105,-0.9380883363940782,0.2730652157571057,0.08448395903578995,0.49581323527606314,-0.06834244752895141,-0.18407723239973067,-0.2617543886648669,-0.2228641911880681,0.16024710230774855,0.6786577838997692,-1.142236601311283,0.046438768658526614,0.31045289547876415,3.7170403434140957,0.5325786056609498,-0.6961809613273137,0.6422830455391815,-0.7362619239858912,0.8232188465018345,0.4589472845566754,0.2730652157571057,1.3528870084169071,2.909054182190894,0.4219795344352679,0.4589472845566754,-0.06834244752895141,-0.10681568420881038,0.046438768658526614,1.4221308141162194,0.16024710230774855,-0.14539417304951105,-0.06834244752895141,0.7872171546294843,-0.10681568420881038,-0.2228641911880681
| 3,447
|
Regulation of membrane potential
| 6
| 63
| 2.071171
| 0.038343
|
P46934,Q9UQB8,O75844,P31751,P63244,Q96PU5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,38,144,146,22
|
2902,3038,2103,1145,38,3234,1242,2687,2010,3006,3363,1833,830,3372,1835,1918,560,1247,3073,1080,1634,3150,144,2820,2208,1435,2821,2480,704,0,3316,2401,843,2404,1358,1755,2831,146,916,3282,919,3176,268,2497,1766,2232,1372,2147,854,1266,622,3019,2644,3309,583,866,22,3381,171,2848,2278,1816,1
|
-0.6163076847411272,-0.7362619239858912,-0.18407723239973067,0.19796354037843203,3.1611459359376193,-1.0603026943246578,0.16024710230774855,-0.4577315218833705,-0.14539417304951105,-0.6961809613273137,-1.6834582174676083,-0.06834244752895141,0.3477336267234822,-1.7680166991740838,-0.06834244752895141,-0.10681568420881038,0.5325786056609498,0.16024710230774855,-0.7764383715343895,0.23556922766931127,0.008285488231352866,-0.8975352684516035,1.3181491405527583,-0.5368230072244451,-0.2228641911880681,0.08448395903578995,-0.5368230072244451,-0.33984190680438486,0.4219795344352679,8.724440398807948,-1.3486452779327809,-0.30074717415258867,0.3477336267234822,-0.30074717415258867,0.1224203206127141,-0.029975155508291253,-0.5368230072244451,1.3181491405527583,0.31045289547876415,-1.1833394006713358,0.31045289547876415,-0.9380883363940782,0.9306838219669343,-0.33984190680438486,-0.029975155508291253,-0.2228641911880681,0.1224203206127141,-0.18407723239973067,0.3477336267234822,0.16024710230774855,0.49581323527606314,-0.6961809613273137,-0.4183346979723081,-1.307185528426478,0.5325786056609498,0.3477336267234822,3.7170403434140957,-1.8529107405085548,1.2134624234635654,-0.5368230072244451,-0.2228641911880681,-0.029975155508291253,8.699167629790622
| 3,447
|
Blepharophimosis
| 14
| 56
| 2.070039
| 0.038449
|
Q96DF8,P38606,P61586,Q9UPQ9,O75844,P11274,Q86UE8,Q08J23,O75648,Q9Y619,P38398,Q03164,Q9UKB1,Q15555
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,189,98,176,38,312,301,439,165,47,232,24,128,442
|
2901,1339,2805,2104,165,38,2108,2383,988,312,1529,3218,2208,3128,1748,232,189,2308,3258,843,520,98,2140,2633,24,439,1090,2874,3017,2975,1455,2241,442,1963,1281,301,1873,724,2654,1796,1971,488,130,1036,2358,681,3265,1812,1815,2455,969,128,176,1333,1599,47
|
-0.6163076847411272,0.1224203206127141,-0.5368230072244451,-0.18407723239973067,1.2134624234635654,3.1611459359376193,-0.18407723239973067,-0.30074717415258867,0.2730652157571057,0.8232188465018345,0.046438768658526614,-1.0194725501820754,-0.2228641911880681,-0.8570755720322065,-0.029975155508291253,1.0018867588079787,1.1432690292803236,-0.2617543886648669,-1.1012242063110105,0.3477336267234822,0.5692445891444328,1.6280595211027935,-0.18407723239973067,-0.4183346979723081,3.6865458322344447,0.6422830455391815,0.23556922766931127,-0.5765164870891749,-0.6961809613273137,-0.6561960301664904,0.08448395903578995,-0.2228641911880681,0.6422830455391815,-0.10681568420881038,0.16024710230774855,0.859129862238441,-0.06834244752895141,0.4219795344352679,-0.4183346979723081,-0.029975155508291253,-0.10681568420881038,0.6058123542920794,1.387547314801095,0.2730652157571057,-0.2617543886648669,0.4589472845566754,-1.1012242063110105,-0.029975155508291253,-0.029975155508291253,-0.30074717415258867,0.31045289547876415,1.4221308141162194,1.2134624234635654,0.16024710230774855,0.046438768658526614,2.8455158089159505
| 3,447
|
oxidase
| 6
| 16
| 2.056883
| 0.039698
|
O75845,P14406,Q6QHF9,Q15800,P13073,Q8NB78
|
Functions
|
Panther Protein class
|
panther_protein_class
|
187,8,16,359,266,92
|
548,2543,187,2288,1244,266,8,1919,1524,3009,432,1639,359,16,863,92
|
0.5325786056609498,-0.379037955370512,1.1432690292803236,-0.2617543886648669,0.16024710230774855,0.9306838219669343,5.867495109069628,-0.10681568420881038,0.046438768658526614,-0.6961809613273137,0.6422830455391815,0.008285488231352866,0.7511237729781655,4.079630186526745,0.3477336267234822,1.6961201650403537
| 3,447
|
Mitotic spindle checkpoint
| 20
| 60
| 2.056877
| 0.039698
|
P63167,Q8NFH4,Q8WYP5,Q96EE3,Q9UJX3,P30260,O00139,Q6P1K2,Q9H1A4,Q9NQS7,Q96DE5,P43034,P30153,Q9UJX2,Q9BZD4,Q12769,Q13362,P53350,Q92674,Q7L7X3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
249,275,676,416,686,513,395,665,326,197,194,190,431,745,493,335,235,116,125,381
|
395,1062,1423,1137,2609,1723,1605,986,431,835,513,190,1842,1165,705,2218,1935,116,999,249,335,1950,235,1448,1091,1267,2240,1775,1857,1861,2835,1959,665,1667,381,2512,1389,275,1291,676,125,194,1685,416,2729,2587,1305,493,326,3351,2893,197,1814,745,686,1899,1992,1594,2858,1058
|
0.6786577838997692,0.23556922766931127,0.08448395903578995,0.19796354037843203,-0.4183346979723081,-0.029975155508291253,0.008285488231352866,0.2730652157571057,0.6422830455391815,0.3477336267234822,0.5692445891444328,1.1432690292803236,-0.06834244752895141,0.19796354037843203,0.4219795344352679,-0.2228641911880681,-0.10681568420881038,1.4566382478660667,0.2730652157571057,0.9663286969491739,0.7872171546294843,-0.10681568420881038,1.0018867588079787,0.08448395903578995,0.23556922766931127,0.16024710230774855,-0.2228641911880681,-0.029975155508291253,-0.06834244752895141,-0.06834244752895141,-0.5368230072244451,-0.10681568420881038,0.4589472845566754,0.008285488231352866,0.7149376676487161,-0.33984190680438486,0.1224203206127141,0.9306838219669343,0.16024710230774855,0.4589472845566754,1.4221308141162194,1.1432690292803236,0.008285488231352866,0.6786577838997692,-0.4577315218833705,-0.379037955370512,0.16024710230774855,0.6058123542920794,0.8232188465018345,-1.5153608569100934,-0.5765164870891749,1.1432690292803236,-0.029975155508291253,0.4219795344352679,0.4589472845566754,-0.06834244752895141,-0.10681568420881038,0.046438768658526614,-0.5368230072244451,0.2730652157571057
| 3,447
|
Meiotic cell cycle process
| 21
| 42
| 2.036812
| 0.041669
|
Q15003,Q9Y2W6,Q08379,Q9BXW9,P49959,P35579,P42695,Q9NTJ3,Q9NQS7,P30153,O95067,Q08J23,P61160,O60921,Q9BZD4,Q12768,O60216,O94901,P53350,Q9BTX1,Q15021
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
411,14,522,681,407,516,405,459,197,431,553,439,437,207,493,334,698,468,116,389,526
|
892,2099,2609,698,1605,207,468,553,1343,1245,2393,431,907,516,405,1534,407,708,116,2405,3012,437,1762,522,439,334,2233,2045,411,526,1656,1392,2071,2165,389,681,493,2527,197,459,2671,14
|
0.31045289547876415,-0.18407723239973067,-0.4183346979723081,0.4219795344352679,0.008285488231352866,1.0727461077752654,0.6058123542920794,0.5325786056609498,0.1224203206127141,0.16024710230774855,-0.30074717415258867,0.6422830455391815,0.31045289547876415,0.5692445891444328,0.6786577838997692,0.046438768658526614,0.6786577838997692,0.4219795344352679,1.4566382478660667,-0.30074717415258867,-0.6961809613273137,0.6422830455391815,-0.029975155508291253,0.5692445891444328,0.6422830455391815,0.7872171546294843,-0.2228641911880681,-0.14539417304951105,0.6786577838997692,0.5692445891444328,0.008285488231352866,0.1224203206127141,-0.14539417304951105,-0.18407723239973067,0.7149376676487161,0.4589472845566754,0.6058123542920794,-0.33984190680438486,1.1432690292803236,0.6422830455391815,-0.4183346979723081,4.6710962008148424
| 3,447
|
Lissencephaly
| 20
| 54
| 2.004494
| 0.045017
|
Q2VPK5,O43175,Q9H2M9,Q6P4I2,P42695,O00139,Q15392,P42356,P23786,Q16625,P38606,P43034,P07942,Q9HC21,O43505,P78527,Q15058,Q86XL3,Q15042,Q96EK5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
377,505,683,286,405,395,42,295,294,575,189,190,558,345,79,211,82,630,622,531
|
395,1233,505,79,1724,558,899,2692,2473,294,650,2479,2700,189,295,405,190,999,2831,211,711,919,1175,1267,622,82,42,2050,1461,575,377,286,1018,630,1794,1291,2728,531,1396,2356,1207,1977,1695,2938,683,1983,2789,345,1812,1594,973,2799,2801,3036
|
0.6786577838997692,0.16024710230774855,0.5692445891444328,1.9321424827289813,-0.029975155508291253,0.5325786056609498,0.31045289547876415,-0.4577315218833705,-0.33984190680438486,0.859129862238441,0.4589472845566754,-0.33984190680438486,-0.4577315218833705,1.1432690292803236,0.859129862238441,0.6786577838997692,1.1432690292803236,0.2730652157571057,-0.5368230072244451,1.0727461077752654,0.4219795344352679,0.31045289547876415,0.19796354037843203,0.16024710230774855,0.49581323527606314,1.8650479272211853,2.9723834308637342,-0.14539417304951105,0.08448395903578995,0.5325786056609498,0.7149376676487161,0.8949511957915331,0.2730652157571057,0.49581323527606314,-0.029975155508291253,0.16024710230774855,-0.4577315218833705,0.5692445891444328,0.1224203206127141,-0.2617543886648669,0.19796354037843203,-0.10681568420881038,0.008285488231352866,-0.6163076847411272,0.4589472845566754,-0.10681568420881038,-0.4972278233176913,0.7872171546294843,-0.029975155508291253,0.046438768658526614,0.31045289547876415,-0.4972278233176913,-0.4972278233176913,-0.6961809613273137
| 3,447
|
Intrinsic component of endoplasmic reticulum membrane
| 37
| 57
| 4.656459
| 0.000003
|
Q8N4V1,Q9P035,Q9BUN8,Q9UBM7,P49069,P51572,Q9Y282,Q9UM00,Q15629,Q9NQC3,Q9Y4P3,Q6Y1H2,Q969X5,Q96A33,Q9HCU5,Q12981,Q15041,O75844,O76024,Q8TB61,O95470,P57088,P61619,Q15125,Q16799,Q8TCT9,Q9H3H5,Q969N2,Q86YN1,Q92643,Q99442,Q6NTF9,O76062,Q86XL3,P27824,Q9NPA0,Q9NZ01
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
5,134,135,400,276,404,26,285,33,35,292,172,429,178,441,439,311,58,189,64,65,73,336,84,119,92,224,481,98,359,360,231,115,246,509,253,127
|
587,627,1003,1418,58,189,115,65,1162,507,3313,509,1471,276,404,73,336,752,439,3007,1890,311,84,33,119,2762,231,172,2154,246,98,5,855,64,92,359,481,429,178,2828,360,2734,135,1360,224,441,253,35,127,134,626,3065,400,285,26,292,1186
|
0.5968202922124238,0.5326129525524724,0.19313737866175912,-0.027269365976897105,2.8295777132185935,1.840651870597142,2.2912039487046916,2.767289755156624,0.10296527861463395,0.7372535957044981,-1.214219613160026,0.7372535957044981,-0.04627372815783212,1.3942178014247664,0.9599094643624182,2.713109541828266,1.156206673163405,0.4006592727447067,0.8871862971088242,-0.7868309696564781,-0.20213507046424417,1.237246593120908,2.555433683915995,3.216350650152123,2.2810653447612044,-0.6029828692428588,1.6420560339548476,1.9638504485042398,-0.30320435577832683,1.5571559613224766,2.4693260750464634,4.040872839878629,0.3156532797160656,2.776248153122407,2.498239242135206,1.0872927564021313,0.8129896825372822,0.9018467708360485,1.9306423672509032,-0.6480246355463081,1.0872927564021313,-0.5806822940457038,2.167755946996452,0.010434058495094673,1.6897278697989968,0.8871862971088242,1.5201769173547421,3.1922316667835537,2.229971341354025,2.178194878551719,0.5487721681964972,-0.8343882553406996,0.9742827906130651,1.3555894999858193,3.396631569290751,1.3165577277068716,0.10296527861463395
| 3,447
|
Cation transmembrane transporter activity
| 38
| 70
| 4.18394
| 0.000029
|
P05141,Q8N4V1,P16615,Q9UDW1,Q9HC21,Q9Y487,O75964,P20020,P56134,Q9UM00,O43772,Q96NB2,O95202,Q93050,Q96ES6,Q8NEW0,P30825,P05023,P51790,Q4KMQ2,Q00325,P55011,Q9H0U3,Q9Y619,Q70HW3,Q86VD7,P12235,P61619,P24539,P56385,P98194,P13073,O43808,Q9HD20,P23634,P00403,P20674,Q13423
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
258,5,136,14,143,149,21,403,405,285,286,296,169,175,431,55,310,309,448,323,450,449,325,329,72,332,208,336,209,337,215,89,347,102,483,245,508,255
|
286,347,2748,21,169,245,309,1969,258,1163,1329,2541,1915,578,879,208,89,136,403,508,2492,3361,483,209,2847,310,1009,1617,2924,2130,1196,3406,448,1677,449,405,337,1076,336,215,450,1779,255,2142,1018,323,652,72,332,5,966,55,2222,175,431,296,912,325,1501,636,143,102,563,14,1253,285,149,2743,329,530
|
1.342624187693322,1.115012567814737,-0.6029828692428588,3.5692505459608204,1.9858304188448097,1.5694020954564156,1.237246593120908,-0.24221132899251827,1.4702992943855286,0.10296527861463395,0.010434058495094673,-0.49290160023430213,-0.2221155959941241,0.6126954261187706,0.2810765284904778,1.7717381563510717,2.517396848234407,2.1572887559147627,0.9599094643624182,0.7372535957044981,-0.471302155269236,-1.3791392568827447,0.7979678150313219,1.7601302536193415,-0.6707700428550947,1.237246593120908,0.19313737866175912,-0.10391188008073553,-0.7167208001281143,-0.30320435577832683,0.0846519922036011,-1.673164747906431,0.8576880629169049,-0.12333709979746053,0.8576880629169049,0.9599094643624182,1.1425261705350076,0.15734332005004562,1.156206673163405,1.7133407362411066,0.8576880629169049,-0.16251400074754818,1.4953208273418972,-0.30320435577832683,0.19313737866175912,1.1969478078787075,0.5163809909451085,2.722191252729754,1.1698368489882653,4.040872839878629,0.2285742779294462,2.8559762796306747,-0.3237756446783554,1.9417437419205628,0.9018467708360485,1.3034558937486695,0.2636616261122957,1.1969478078787075,-0.04627372815783212,0.5326129525524724,2.1362689307517044,2.42065765575822,0.6442383099094389,3.7489696574923244,0.06624331600225977,1.3555894999858193,2.0938827725307765,-0.5806822940457038,1.1834170961274035,0.7065124420438686
| 3,447
|
Protein localization to mitochondrion
| 31
| 59
| 4.157442
| 0.000032
|
P55786,Q9NS69,O60830,Q99595,Q9Y512,Q8N4H5,P51572,Q9Y5J9,Q53H12,Q9Y6C9,O43615,P30536,Q9NX47,Q9H270,Q9H300,Q15070,O00170,O95817,O95140,Q9Y276,O00429,Q10713,Q9P0J0,O96008,P52789,Q15388,O14925,Q9BZL1,Q8WWC4,Q99797,Q9UBE0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
516,3,4,9,274,20,404,282,549,37,543,41,301,562,307,53,435,438,437,461,588,344,87,464,612,353,106,497,363,502,511
|
435,2066,588,1372,106,543,4,2971,2277,437,1914,2280,438,824,464,708,1971,3248,3372,1719,1775,2590,41,1068,1873,611,404,612,516,2401,344,1683,53,353,1984,737,549,1742,2153,20,2103,363,9,502,497,562,307,1028,3,301,87,511,1414,461,1155,1768,274,282,37
|
0.8871862971088242,-0.28275422227728697,0.5968202922124238,-0.008367163295788871,2.391162989421182,0.6599073521556105,4.1444590074269065,-0.7632999174742385,-0.36528796300450794,0.8871862971088242,-0.2221155959941241,-0.36528796300450794,0.8871862971088242,0.3328168814905901,0.8279499860422683,0.4341047300866308,-0.24221132899251827,-1.0827717031939503,-1.4359917276919325,-0.14287070187912912,-0.16251400074754818,-0.5146374427323911,3.0360255403392498,0.15734332005004562,-0.20213507046424417,0.5648593382990243,0.9599094643624182,0.5648593382990243,0.7219155083838219,-0.4285051553274654,1.1287949380852866,-0.12333709979746053,2.8647369895860946,1.1011786466586961,-0.24221132899251827,0.4174209793635682,0.6599073521556105,-0.14287070187912912,-0.30320435577832683,3.5912373381541602,-0.28275422227728697,1.0733544735925842,3.8600030048314653,0.7677371814906225,0.7828838337881776,0.6442383099094389,1.2505830026120932,0.19313737866175912,4.276636208213452,1.2771132720400578,2.5269406716164067,0.7372535957044981,-0.008367163295788871,0.8428492678399792,0.12118423630495645,-0.14287070187912912,1.40700578874686,1.3685099847547963,3.1760717839026786
| 3,447
|
SLC superfamily of solute carriers
| 30
| 47
| 4.116756
| 0.000038
|
P05141,Q9HC21,O95563,Q9UBX3,O43772,Q96H78,Q9Y6C9,Q8IXU6,Q96NB2,O95202,Q6NUK1,Q9H2D1,Q6KCM7,P12236,Q8NEW0,P30825,Q9NZJ7,Q8TB61,Q00325,Q9H2V7,Q9H0U3,Q9Y619,Q70HW3,Q9BSK2,Q86VD7,P12235,O43808,P53985,Q5T1Q4,Q7L0J3
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
258,143,269,31,286,165,37,295,296,169,425,46,306,183,55,310,187,64,450,69,325,329,72,76,332,208,347,237,368,123
|
1003,286,347,1669,169,269,258,1915,844,208,183,310,661,1233,237,449,450,829,1018,368,306,3434,425,1450,72,123,332,295,55,64,165,296,1699,76,912,325,46,69,1501,636,143,187,31,1660,329,37,530
|
0.19313737866175912,1.342624187693322,1.115012567814737,-0.12333709979746053,1.9858304188448097,1.40700578874686,1.4702992943855286,-0.2221155959941241,0.3156532797160656,1.7717381563510717,1.8859120022561358,1.237246593120908,0.500075572431892,0.06624331600225977,1.6179929845170453,0.8576880629169049,0.8576880629169049,0.3328168814905901,0.19313737866175912,1.059363369451296,1.2505830026120932,-2.5135956035021803,0.9164488273167519,-0.027269365976897105,2.722191252729754,2.2607083952402736,1.1698368489882653,1.3034558937486695,2.8559762796306747,2.776248153122407,2.018566145549778,1.3034558937486695,-0.12333709979746053,2.6948832866620145,0.2636616261122957,1.1969478078787075,2.9513000228072084,2.749311957797667,-0.04627372815783212,0.5326129525524724,2.1362689307517044,1.8633490032538682,3.272073939679055,-0.10391188008073553,1.1834170961274035,3.1760717839026786,0.7065124420438686
| 3,447
|
Anion transmembrane transport
| 25
| 47
| 4.027871
| 0.000056
|
P05141,Q9HC21,P45880,O95563,P21796,Q9UBX3,Q14728,Q96NB2,P08183,Q9UHG3,Q9H2D1,P12236,Q15041,P30825,Q8TB61,P51790,Q4KMQ2,Q00325,Q9Y619,Q86VD7,P12235,Q9Y277,O43808,P53985,O60831
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
258,143,16,269,27,31,417,296,299,44,46,183,311,310,64,448,323,450,329,332,208,82,347,237,235
|
347,235,1669,1160,269,258,3091,299,1915,208,183,27,310,1231,661,16,448,749,1233,237,449,450,829,1205,417,311,1018,323,2762,332,64,1143,296,1699,912,46,1501,636,143,1029,31,44,1660,82,1862,329,530
|
1.115012567814737,1.6179929845170453,-0.12333709979746053,0.10296527861463395,1.40700578874686,1.4702992943855286,-0.8826227148684676,1.2771132720400578,-0.2221155959941241,1.7717381563510717,1.8859120022561358,3.3503698232892996,1.237246593120908,0.06624331600225977,0.500075572431892,3.6994359897329634,0.8576880629169049,0.4006592727447067,0.06624331600225977,1.6179929845170453,0.8576880629169049,0.8576880629169049,0.3328168814905901,0.0846519922036011,0.9454796834826562,1.237246593120908,0.19313737866175912,1.1969478078787075,-0.6029828692428588,1.1698368489882653,2.776248153122407,0.12118423630495645,1.3034558937486695,-0.12333709979746053,0.2636616261122957,2.9513000228072084,-0.04627372815783212,0.5326129525524724,2.1362689307517044,0.19313737866175912,3.272073939679055,2.9683894129100112,-0.10391188008073553,2.6118073444066714,-0.1822683354853108,1.1834170961274035,0.7065124420438686
| 3,447
|
Intrinsic component of organelle membrane
| 92
| 130
| 3.898553
| 0.000097
|
O60830,Q8N4V1,Q99595,O75880,Q9Y2R0,Q9Y282,Q8WVX9,Q15629,Q53H12,Q9NQC3,Q16891,P57105,Q15070,O75844,Q8TB61,O95470,O43505,P57088,P20339,Q15125,A0FGR8,Q8TCT9,Q86YN1,O14925,Q9P0I2,O76062,Q16799,Q9H9B4,Q9BTV4,Q7L0J3,Q9NZ01,Q14739,Q9P035,Q9BUN8,Q5XKP0,Q9HC21,Q9BUR5,O95070,Q6Y1H2,Q96A33,O15118,O76024,P12235,Q6UXV4,P98194,O15258,L0R6Q1,Q9H3H5,Q9H3K2,Q9BWH2,Q6NTF9,Q86XL3,Q5SNT2,Q9NPA0,Q8IWA4,Q9Y512,O95563,P49069,Q9UM00,Q9Y4P3,Q96NB2,Q15041,P50416,P61619,P42892,O43819,O43808,P56589,Q15388,Q92643,Q99442,Q9UBM7,Q13505,Q6ZRP7,P51572,P20020,O75431,O60499,O94901,Q969X5,Q9H9P8,Q9HCU5,Q12981,O95140,Q00325,Q9UH99,O96008,Q969N2,Q9NVH1,Q16134,P27824,P10321
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
4,5,9,520,17,26,541,33,549,35,558,556,53,58,64,65,577,73,579,84,587,92,98,106,626,115,119,636,635,123,127,128,134,135,137,143,147,171,172,178,186,189,208,213,215,219,217,224,225,227,231,246,249,253,256,274,269,276,285,292,296,311,316,336,341,340,347,351,353,359,360,400,407,409,404,403,413,423,427,429,433,441,439,437,450,474,464,481,489,504,509,507
|
587,217,627,106,1003,186,219,1418,577,347,340,423,4,413,58,520,189,115,2277,427,171,437,65,269,464,1162,507,208,403,579,3313,509,1471,3119,341,276,748,316,1168,404,351,73,556,2638,336,215,450,752,1575,439,407,3007,128,1890,311,53,84,850,353,33,504,3236,119,558,549,249,137,2762,231,213,172,409,123,2154,246,872,98,256,2378,2683,5,855,2610,966,64,92,541,359,481,429,178,296,2828,360,9,1540,2734,635,135,147,227,1360,224,225,636,433,143,441,253,35,2835,489,1364,127,134,626,3065,400,1658,3147,474,285,26,17,1094,1768,292,2180,274,1186
|
0.5968202922124238,1.7015526819939406,0.5326129525524724,2.391162989421182,0.19313737866175912,1.8633490032538682,1.7015526819939406,-0.027269365976897105,0.6126954261187706,1.115012567814737,1.1287949380852866,0.9164488273167519,4.1444590074269065,0.9454796834826562,2.8295777132185935,0.7065124420438686,1.840651870597142,2.2912039487046916,-0.36528796300450794,0.9018467708360485,1.9638504485042398,0.8871862971088242,2.767289755156624,1.40700578874686,0.8279499860422683,0.10296527861463395,0.7372535957044981,1.7717381563510717,0.9599094643624182,0.6126954261187706,-1.214219613160026,0.7372535957044981,-0.04627372815783212,-0.9070004618348723,1.1287949380852866,1.3942178014247664,0.4006592727447067,1.2238621747785425,0.10296527861463395,0.9599094643624182,1.1011786466586961,2.713109541828266,0.6442383099094389,-0.5365115565809986,1.156206673163405,1.7133407362411066,0.8576880629169049,0.4006592727447067,-0.08459375235902318,0.8871862971088242,0.9599094643624182,-0.7868309696564781,2.2196712726732395,-0.20213507046424417,1.237246593120908,2.8647369895860946,2.555433683915995,0.3156532797160656,1.1011786466586961,3.216350650152123,0.75252729309868,-1.0570912841778808,2.2810653447612044,0.6442383099094389,0.6599073521556105,1.5448699088190703,2.1572887559147627,-0.6029828692428588,1.6420560339548476,1.7250922784124725,1.9638504485042398,0.9599094643624182,2.2607083952402736,-0.30320435577832683,1.5571559613224766,0.29840678518812824,2.4693260750464634,1.4953208273418972,-0.40730404219216754,-0.5585258554562905,4.040872839878629,0.3156532797160656,-0.5146374427323911,0.2285742779294462,2.776248153122407,2.498239242135206,0.6755089741541659,1.0872927564021313,0.8129896825372822,0.9018467708360485,1.9306423672509032,1.3034558937486695,-0.6480246355463081,1.0872927564021313,3.8600030048314653,-0.06538144972417397,-0.5806822940457038,0.5326129525524724,2.167755946996452,2.1045230542075872,1.6540303882823562,0.010434058495094673,1.6897278697989968,1.6659669752722266,0.5326129525524724,0.9018467708360485,2.1362689307517044,0.8871862971088242,1.5201769173547421,3.1922316667835537,-0.6480246355463081,0.7979678150313219,0.010434058495094673,2.229971341354025,2.178194878551719,0.5487721681964972,-0.8343882553406996,0.9742827906130651,-0.10391188008073553,-0.9315555215226238,0.8279499860422683,1.3555894999858193,3.396631569290751,3.656498320463535,0.15734332005004562,-0.14287070187912912,1.3165577277068716,-0.30320435577832683,1.40700578874686,0.10296527861463395
| 3,447
|
Anion transport
| 38
| 75
| 3.87777
| 0.000105
|
P05141,P0CG08,Q9Y6M7,Q9NP80,Q15907,Q9HC21,P45880,O95563,P21796,P28288,Q9UBX3,Q14728,P07602,Q96NB2,Q6NUK1,P30536,P08183,Q9UHG3,Q9H2D1,Q6KCM7,P12236,Q15041,P30825,Q9NZJ7,Q8TB61,P51790,Q4KMQ2,Q00325,P55011,Q9Y619,P14174,Q86VD7,P12235,Q9Y277,O43808,P53985,O60831,Q7L0J3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
258,514,530,398,141,143,16,269,27,287,31,417,166,296,425,41,299,44,46,306,183,311,310,187,64,448,323,450,449,329,330,332,208,82,347,237,235,123
|
1909,666,531,347,641,235,1669,1160,269,2121,258,3091,166,299,1915,514,844,208,183,330,730,27,287,41,310,1231,661,16,448,749,1233,237,3028,449,3407,450,829,889,1683,1205,417,311,649,1018,141,323,306,3434,2762,425,1450,123,332,64,1143,296,1699,912,2380,46,1501,636,143,1029,398,187,31,44,1505,1660,82,1862,329,3273,530
|
-0.2221155959941241,0.4836959753352828,0.6910437992675935,1.115012567814737,0.5163809909451085,1.6179929845170453,-0.12333709979746053,0.10296527861463395,1.40700578874686,-0.30320435577832683,1.4702992943855286,-0.8826227148684676,2.007685211650335,1.2771132720400578,-0.2221155959941241,0.7219155083838219,0.3156532797160656,1.7717381563510717,1.8859120022561358,1.1698368489882653,0.4174209793635682,3.3503698232892996,1.342624187693322,3.0360255403392498,1.237246593120908,0.06624331600225977,0.500075572431892,3.6994359897329634,0.8576880629169049,0.4006592727447067,0.06624331600225977,1.6179929845170453,-0.8105262504581725,0.8576880629169049,-1.673164747906431,0.8576880629169049,0.3328168814905901,0.2810765284904778,-0.12333709979746053,0.0846519922036011,0.9454796834826562,1.237246593120908,0.5163809909451085,0.19313737866175912,2.1362689307517044,1.1969478078787075,1.2505830026120932,-2.5135956035021803,-0.6029828692428588,0.9164488273167519,-0.027269365976897105,2.2607083952402736,1.1698368489882653,2.776248153122407,0.12118423630495645,1.3034558937486695,-0.12333709979746053,0.2636616261122957,-0.40730404219216754,2.9513000228072084,-0.04627372815783212,0.5326129525524724,2.1362689307517044,0.19313737866175912,0.9742827906130651,1.8633490032538682,3.272073939679055,2.9683894129100112,-0.04627372815783212,-0.10391188008073553,2.6118073444066714,-0.1822683354853108,1.1834170961274035,-1.1086506296557357,0.7065124420438686
| 3,447
|
Lipid biosynthesis
| 28
| 58
| 3.839397
| 0.000123
|
Q14739,Q9P035,Q15800,Q8NF37,Q9UBM7,Q53GQ0,Q8IVS2,P14324,P48651,Q16850,Q15392,Q6Y1H2,P27544,P37268,Q9H7Z7,Q99943,Q86UL3,Q15125,O95674,Q96G23,O75845,Q96N66,O76062,Q8NBQ5,P54646,Q9HCL2,Q9NZ01,Q9BY49
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
128,134,7,264,400,148,281,402,161,164,40,172,61,199,202,473,471,84,220,103,357,232,115,373,375,506,127,385
|
919,3246,627,357,115,220,1161,3229,402,61,805,199,2129,1621,161,619,1434,1475,750,1102,375,3314,3397,1683,2375,128,84,2860,701,40,581,7,164,148,172,471,281,373,264,541,2649,908,103,232,473,2735,385,1500,202,896,506,2475,2478,127,134,400,1658,1505
|
0.2461611801381823,-1.0827717031939503,0.5326129525524724,1.0872927564021313,2.2912039487046916,1.7015526819939406,0.10296527861463395,-1.0570912841778808,0.9599094643624182,2.7851863493439573,0.349898446135214,1.794848233650915,-0.30320435577832683,-0.10391188008073553,2.040236030803411,0.5487721681964972,-0.027269365976897105,-0.04627372815783212,0.4006592727447067,0.13930990831158938,1.0312209548801738,-1.214219613160026,-1.5823993310130011,-0.12333709979746053,-0.40730404219216754,2.2196712726732395,2.555433683915995,-0.6707700428550947,0.45071130368158374,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,2.0938827725307765,1.9638504485042398,0.8279499860422683,1.3685099847547963,1.045319009782404,1.445109921894803,0.6755089741541659,-0.5365115565809986,0.2636616261122957,2.410850833556328,1.6420560339548476,0.8279499860422683,-0.5806822940457038,1.0028619724328278,-0.04627372815783212,1.794848233650915,0.2810765284904778,0.75252729309868,-0.44983727276622243,-0.44983727276622243,2.229971341354025,2.178194878551719,0.9742827906130651,-0.10391188008073553,-0.04627372815783212
| 3,447
|
Organic anion transport
| 25
| 52
| 3.837667
| 0.000124
|
P05141,Q9NP80,Q9HC21,O95563,Q9UBX3,P28288,Q14728,P07602,Q96NB2,Q6NUK1,Q9H2D1,Q6KCM7,P12236,Q15041,P30825,Q9NZJ7,Q8TB61,Q9Y619,P14174,Q86VD7,P12235,O43808,P53985,O60831,Q7L0J3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
258,398,143,269,31,287,417,166,296,425,46,306,183,311,310,187,64,329,330,332,208,347,237,235,123
|
666,347,235,1669,1160,269,2121,258,3091,166,1915,844,208,183,330,730,287,310,1231,661,1233,237,449,3407,829,889,1683,417,311,649,1018,306,2762,425,1450,123,332,64,1143,296,1699,46,1501,636,143,398,187,31,1505,1660,329,530
|
0.4836959753352828,1.115012567814737,1.6179929845170453,-0.12333709979746053,0.10296527861463395,1.40700578874686,-0.30320435577832683,1.4702992943855286,-0.8826227148684676,2.007685211650335,-0.2221155959941241,0.3156532797160656,1.7717381563510717,1.8859120022561358,1.1698368489882653,0.4174209793635682,1.342624187693322,1.237246593120908,0.06624331600225977,0.500075572431892,0.06624331600225977,1.6179929845170453,0.8576880629169049,-1.673164747906431,0.3328168814905901,0.2810765284904778,-0.12333709979746053,0.9454796834826562,1.237246593120908,0.5163809909451085,0.19313737866175912,1.2505830026120932,-0.6029828692428588,0.9164488273167519,-0.027269365976897105,2.2607083952402736,1.1698368489882653,2.776248153122407,0.12118423630495645,1.3034558937486695,-0.12333709979746053,2.9513000228072084,-0.04627372815783212,0.5326129525524724,2.1362689307517044,0.9742827906130651,1.8633490032538682,3.272073939679055,-0.04627372815783212,-0.10391188008073553,1.1834170961274035,0.7065124420438686
| 3,447
|
Inner mitochondrial membrane protein complex
| 40
| 77
| 3.820092
| 0.000133
|
O75306,P14406,O60830,O43676,Q99595,Q5XKP0,Q99623,Q9UDW1,Q9Y512,P21912,Q13505,P03886,Q9BUR5,Q96IX5,O75964,O14949,P56134,O75431,Q53H12,P56378,Q99643,Q16891,Q96CU9,O75438,P12236,O96000,Q86Y39,Q9Y276,O95168,P24539,P56385,Q6UXV4,Q9Y6M9,Q9P0J0,P13073,Q9NVH1,P51970,O14925,P00403,P20674
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
382,1,4,8,9,137,271,14,274,270,407,146,147,411,21,24,405,413,549,167,432,558,180,181,183,568,71,461,453,209,337,213,86,87,89,489,484,106,245,508
|
2182,1597,106,24,8,2272,4,1327,382,706,413,181,2117,2748,21,453,3383,2390,568,245,146,1128,1163,578,802,879,183,89,1,1228,922,3336,508,270,981,209,2847,3345,2495,1009,2496,1617,3119,1196,3406,3214,484,405,167,337,407,3142,1631,558,737,549,137,213,71,966,2103,180,411,9,271,432,1540,147,1028,489,1364,87,14,461,2180,274,86
|
-0.3237756446783554,-0.10391188008073553,2.391162989421182,3.411935775289236,3.873674680039861,-0.36528796300450794,4.1444590074269065,0.010434058495094673,1.0028619724328278,0.4341047300866308,0.9454796834826562,1.9083425678170867,-0.30320435577832683,-0.6029828692428588,3.5692505459608204,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,0.10296527861463395,0.6126954261187706,0.349898446135214,0.2810765284904778,1.8859120022561358,2.517396848234407,4.313649129144161,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,1.40700578874686,0.21089999179645574,1.7601302536193415,-0.6707700428550947,-1.3232487120310719,-0.471302155269236,0.19313737866175912,-0.471302155269236,-0.10391188008073553,-0.9070004618348723,0.0846519922036011,-1.673164747906431,-1.0316061132826644,0.7979678150313219,0.9599094643624182,1.9967733661723275,1.1425261705350076,0.9599094643624182,-0.9315555215226238,-0.10391188008073553,0.6442383099094389,0.4174209793635682,0.6599073521556105,2.1572887559147627,1.7250922784124725,2.7312521573765434,0.2285742779294462,-0.28275422227728697,1.9195087103543416,0.9599094643624182,3.8600030048314653,1.40700578874686,0.9018467708360485,-0.06538144972417397,2.1045230542075872,0.19313737866175912,0.7979678150313219,0.010434058495094673,2.5269406716164067,3.7489696574923244,0.8428492678399792,-0.30320435577832683,1.40700578874686,2.5364613381868493
| 3,447
|
er
| 50
| 89
| 3.805147
| 0.000142
|
Q14739,Q8N4V1,Q8NF37,Q9Y3E0,Q9Y487,O00264,P04844,Q00765,P51572,Q8TCJ2,Q9UM00,P48651,Q9NQC3,Q07065,Q16850,Q99640,O60499,Q15392,O15173,P46977,Q96A33,Q9Y5M8,O96005,Q12981,Q15041,Q15738,O95470,Q13190,Q9P2W9,Q86W74,P61026,Q06136,Q9NR31,Q8NHH9,Q15125,Q86UL3,P49755,Q15363,Q969Q5,O95674,P04843,Q96N66,O75845,Q9P0I2,O15269,Q9NTJ5,Q86Y07,P27824,Q9NPA0,O15270
|
Localization
|
OpenCell Localization
|
opencell_localization
|
128,5,264,393,149,151,537,280,404,540,285,161,35,163,164,419,423,40,42,174,178,50,51,439,311,581,65,322,68,324,580,200,206,339,84,471,343,222,90,220,607,232,357,626,239,371,244,509,253,628
|
151,627,42,239,628,1418,423,3212,1064,357,1160,2626,65,220,51,1161,607,537,2072,1556,2125,1559,509,2635,174,1621,161,343,3026,404,2369,3391,1922,953,580,887,790,888,280,200,163,1391,439,322,128,1890,311,84,222,40,581,1892,164,1450,3031,471,324,244,5,855,2610,264,339,2611,540,892,1994,90,967,178,719,232,419,2734,3350,1360,1088,253,35,206,371,626,2529,68,285,1860,393,149,50
|
2.0725136772787915,0.5326129525524724,3.010795820978051,1.6059037631322783,0.5326129525524724,-0.027269365976897105,0.9164488273167519,-1.0316061132826644,0.15734332005004562,1.0872927564021313,0.10296527861463395,-0.5365115565809986,2.767289755156624,1.7015526819939406,2.9082535644185374,0.10296527861463395,0.5648593382990243,0.6755089741541659,-0.28275422227728697,-0.08459375235902318,-0.30320435577832683,-0.08459375235902318,0.7372535957044981,-0.5365115565809986,1.9417437419205628,-0.10391188008073553,2.040236030803411,1.1287949380852866,-0.8105262504581725,0.9599094643624182,-0.40730404219216754,-1.5231044801746638,-0.2221155959941241,0.2285742779294462,0.6126954261187706,0.2810765284904778,0.3668988157742944,0.2810765284904778,1.3813859753747217,1.794848233650915,2.040236030803411,-0.008367163295788871,0.8871862971088242,1.1969478078787075,2.2196712726732395,-0.20213507046424417,1.237246593120908,2.555433683915995,1.7015526819939406,3.0610973203490204,0.6126954261187706,-0.20213507046424417,2.0294163563584418,-0.027269365976897105,-0.8105262504581725,0.8279499860422683,1.1969478078787075,1.5816085902590042,4.040872839878629,0.3156532797160656,-0.5146374427323911,1.445109921894803,1.1425261705350076,-0.5146374427323911,0.6755089741541659,0.2810765284904778,-0.24221132899251827,2.5078297460632952,0.2285742779294462,1.9306423672509032,0.4341047300866308,1.6420560339548476,0.9454796834826562,-0.5806822940457038,-1.3232487120310719,0.010434058495094673,0.15734332005004562,1.5201769173547421,3.1922316667835537,1.7833107392720506,1.059363369451296,0.5487721681964972,-0.471302155269236,2.7583110565843194,1.3555894999858193,-0.1822683354853108,0.9886001370636728,2.0938827725307765,2.9341371514763055
| 3,447
|
Mitochondrial carrier domain superfamily [IPR023395]
| 17
| 24
| 3.773567
| 0.000161
|
O43772,P05141,Q96H78,Q9Y6C9,Q9Y619,Q70HW3,Q6NUK1,Q9BSK2,Q86VD7,Q9HC21,Q9H2D1,P12235,Q6KCM7,O43808,P12236,Q9NZJ7,Q9UBX3
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
286,258,165,37,329,72,425,76,332,143,46,208,306,347,183,187,31
|
286,347,1669,258,208,183,1233,450,829,306,425,72,332,165,1699,76,46,1501,143,187,31,1660,329,37
|
1.342624187693322,1.115012567814737,-0.12333709979746053,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.06624331600225977,0.8576880629169049,0.3328168814905901,1.2505830026120932,0.9164488273167519,2.722191252729754,1.1698368489882653,2.018566145549778,-0.12333709979746053,2.6948832866620145,2.9513000228072084,-0.04627372815783212,2.1362689307517044,1.8633490032538682,3.272073939679055,-0.10391188008073553,1.1834170961274035,3.1760717839026786
| 3,447
|
Mitochondrial substrate/solute carrier [IPR018108]
| 17
| 24
| 3.773567
| 0.000161
|
O43772,P05141,Q96H78,Q9Y6C9,Q9Y619,Q70HW3,Q6NUK1,Q9BSK2,Q86VD7,Q9HC21,Q9H2D1,P12235,Q6KCM7,O43808,P12236,Q9NZJ7,Q9UBX3
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
286,258,165,37,329,72,425,76,332,143,46,208,306,347,183,187,31
|
286,347,1669,258,208,183,1233,450,829,306,425,72,332,165,1699,76,46,1501,143,187,31,1660,329,37
|
1.342624187693322,1.115012567814737,-0.12333709979746053,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.06624331600225977,0.8576880629169049,0.3328168814905901,1.2505830026120932,0.9164488273167519,2.722191252729754,1.1698368489882653,2.018566145549778,-0.12333709979746053,2.6948832866620145,2.9513000228072084,-0.04627372815783212,2.1362689307517044,1.8633490032538682,3.272073939679055,-0.10391188008073553,1.1834170961274035,3.1760717839026786
| 3,447
|
SLC25 family of mitochondrial transporters
| 17
| 24
| 3.773567
| 0.000161
|
O43772,P05141,Q96H78,Q9Y6C9,Q9Y619,Q70HW3,Q6NUK1,Q9BSK2,Q86VD7,Q9HC21,Q9H2D1,P12235,Q6KCM7,O43808,P12236,Q9NZJ7,Q9UBX3
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
286,258,165,37,329,72,425,76,332,143,46,208,306,347,183,187,31
|
286,347,1669,258,208,183,1233,450,829,306,425,72,332,165,1699,76,46,1501,143,187,31,1660,329,37
|
1.342624187693322,1.115012567814737,-0.12333709979746053,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.06624331600225977,0.8576880629169049,0.3328168814905901,1.2505830026120932,0.9164488273167519,2.722191252729754,1.1698368489882653,2.018566145549778,-0.12333709979746053,2.6948832866620145,2.9513000228072084,-0.04627372815783212,2.1362689307517044,1.8633490032538682,3.272073939679055,-0.10391188008073553,1.1834170961274035,3.1760717839026786
| 3,447
|
Inorganic molecular entity transmembrane transporter activity
| 38
| 74
| 3.697719
| 0.000218
|
P05141,P0CG08,Q8N4V1,Q9Y6M7,P16615,Q9UDW1,P45880,Q9Y487,O75964,O43681,P20020,P21796,P56134,Q9UM00,Q9UBX3,O95202,Q9NVV0,Q93050,Q96ES6,P05023,P51790,Q4KMQ2,Q00325,P55011,Q9H0U3,P12235,P61619,P24539,P56385,Q9Y277,P98194,P13073,Q9HD20,P23634,P00403,Q99797,P20674,Q13423
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
258,514,5,530,136,14,16,149,21,531,403,27,405,285,31,169,563,175,431,309,448,323,450,449,325,208,336,209,337,82,215,89,102,483,245,502,508,255
|
1909,531,2748,21,169,245,309,1969,258,1163,1329,2541,1915,578,514,879,208,89,136,403,508,2492,3361,27,483,209,2847,1009,1231,1617,2924,2130,16,1196,3406,448,749,1677,449,405,337,1076,336,215,450,1779,829,255,2142,323,3434,2762,652,5,966,1143,2222,175,431,502,912,325,1501,102,563,31,14,1253,285,82,149,2743,3273,530
|
-0.2221155959941241,0.6910437992675935,-0.6029828692428588,3.5692505459608204,1.9858304188448097,1.5694020954564156,1.237246593120908,-0.24221132899251827,1.4702992943855286,0.10296527861463395,0.010434058495094673,-0.49290160023430213,-0.2221155959941241,0.6126954261187706,0.7219155083838219,0.2810765284904778,1.7717381563510717,2.517396848234407,2.1572887559147627,0.9599094643624182,0.7372535957044981,-0.471302155269236,-1.3791392568827447,3.3503698232892996,0.7979678150313219,1.7601302536193415,-0.6707700428550947,0.19313737866175912,0.06624331600225977,-0.10391188008073553,-0.7167208001281143,-0.30320435577832683,3.6994359897329634,0.0846519922036011,-1.673164747906431,0.8576880629169049,0.4006592727447067,-0.12333709979746053,0.8576880629169049,0.9599094643624182,1.1425261705350076,0.15734332005004562,1.156206673163405,1.7133407362411066,0.8576880629169049,-0.16251400074754818,0.3328168814905901,1.4953208273418972,-0.30320435577832683,1.1969478078787075,-2.5135956035021803,-0.6029828692428588,0.5163809909451085,4.040872839878629,0.2285742779294462,0.12118423630495645,-0.3237756446783554,1.9417437419205628,0.9018467708360485,0.7677371814906225,0.2636616261122957,1.1969478078787075,-0.04627372815783212,2.42065765575822,0.6442383099094389,3.272073939679055,3.7489696574923244,0.06624331600225977,1.3555894999858193,2.6118073444066714,2.0938827725307765,-0.5806822940457038,-1.1086506296557357,0.7065124420438686
| 3,447
|
Ion transmembrane transporter activity
| 53
| 101
| 3.69499
| 0.00022
|
P05141,P0CG08,Q8N4V1,Q9Y6M7,P16615,Q9UDW1,Q9HC21,P45880,O95563,O75964,Q9Y487,P20020,P21796,P56134,Q9UM00,Q9UBX3,O43772,Q14728,Q96NB2,O95202,Q6NUK1,Q9H2D1,Q93050,Q96ES6,Q6KCM7,P12236,Q8NEW0,P30825,P05023,Q8TB61,P51790,Q4KMQ2,Q00325,Q9H0U3,P55011,Q9Y619,Q70HW3,Q86VD7,P12235,P24539,Q9Y277,P61619,P56385,P98194,P13073,O43808,Q9HD20,P23634,P53985,Q9BVC6,P00403,P20674,Q13423
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
258,514,5,530,136,14,143,16,269,21,149,403,27,405,285,31,286,417,296,169,425,46,175,431,306,183,55,310,309,64,448,323,450,325,449,329,72,332,208,209,82,336,337,215,89,347,102,483,237,370,245,508,255
|
1909,666,531,286,347,1669,2748,21,169,269,245,309,1969,258,1163,1329,2541,1915,578,514,879,844,208,183,89,136,403,508,2492,3361,27,483,209,2847,310,1009,1231,1617,2924,2130,661,16,1196,3406,448,749,1233,237,1677,449,405,337,1076,336,215,450,1779,829,255,2142,417,1018,323,306,3434,2762,425,1450,652,72,332,5,966,55,64,1143,2222,175,431,296,1699,370,912,325,46,1501,636,143,102,563,31,14,1253,1660,285,82,149,2743,329,3273,530
|
-0.2221155959941241,0.4836959753352828,0.6910437992675935,1.342624187693322,1.115012567814737,-0.12333709979746053,-0.6029828692428588,3.5692505459608204,1.9858304188448097,1.40700578874686,1.5694020954564156,1.237246593120908,-0.24221132899251827,1.4702992943855286,0.10296527861463395,0.010434058495094673,-0.49290160023430213,-0.2221155959941241,0.6126954261187706,0.7219155083838219,0.2810765284904778,0.3156532797160656,1.7717381563510717,1.8859120022561358,2.517396848234407,2.1572887559147627,0.9599094643624182,0.7372535957044981,-0.471302155269236,-1.3791392568827447,3.3503698232892996,0.7979678150313219,1.7601302536193415,-0.6707700428550947,1.237246593120908,0.19313737866175912,0.06624331600225977,-0.10391188008073553,-0.7167208001281143,-0.30320435577832683,0.500075572431892,3.6994359897329634,0.0846519922036011,-1.673164747906431,0.8576880629169049,0.4006592727447067,0.06624331600225977,1.6179929845170453,-0.12333709979746053,0.8576880629169049,0.9599094643624182,1.1425261705350076,0.15734332005004562,1.156206673163405,1.7133407362411066,0.8576880629169049,-0.16251400074754818,0.3328168814905901,1.4953208273418972,-0.30320435577832683,0.9454796834826562,0.19313737866175912,1.1969478078787075,1.2505830026120932,-2.5135956035021803,-0.6029828692428588,0.9164488273167519,-0.027269365976897105,0.5163809909451085,2.722191252729754,1.1698368489882653,4.040872839878629,0.2285742779294462,2.8559762796306747,2.776248153122407,0.12118423630495645,-0.3237756446783554,1.9417437419205628,0.9018467708360485,1.3034558937486695,-0.12333709979746053,1.059363369451296,0.2636616261122957,1.1969478078787075,2.9513000228072084,-0.04627372815783212,0.5326129525524724,2.1362689307517044,2.42065765575822,0.6442383099094389,3.272073939679055,3.7489696574923244,0.06624331600225977,-0.10391188008073553,1.3555894999858193,2.6118073444066714,2.0938827725307765,-0.5806822940457038,1.1834170961274035,-1.1086506296557357,0.7065124420438686
| 3,447
|
Intrinsic component of mitochondrial membrane
| 30
| 46
| 3.691225
| 0.000223
|
Q8IWA4,O60830,Q99595,Q5XKP0,Q9HC21,Q9Y512,Q13505,O95563,Q9BUR5,O75880,Q9Y2R0,O75431,Q53H12,Q96NB2,Q16891,Q9H9P8,Q15070,O95140,P50416,Q00325,P12235,Q6UXV4,O96008,O43819,Q15388,Q9H3K2,Q9BWH2,Q9NVH1,O14925,Q16134
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
256,4,9,137,143,274,407,269,147,520,17,413,549,296,558,433,53,437,316,450,208,213,464,340,353,225,227,489,106,504
|
106,340,4,413,520,2277,437,269,464,208,3119,748,316,556,450,407,53,353,504,3236,558,549,137,213,256,2378,2683,966,296,9,1540,147,227,225,636,433,143,2835,489,1364,1658,3147,17,1768,2180,274
|
2.391162989421182,1.1287949380852866,4.1444590074269065,0.9454796834826562,0.7065124420438686,-0.36528796300450794,0.8871862971088242,1.40700578874686,0.8279499860422683,1.7717381563510717,-0.9070004618348723,0.4006592727447067,1.2238621747785425,0.6442383099094389,0.8576880629169049,0.9599094643624182,2.8647369895860946,1.1011786466586961,0.75252729309868,-1.0570912841778808,0.6442383099094389,0.6599073521556105,2.1572887559147627,1.7250922784124725,1.4953208273418972,-0.40730404219216754,-0.5585258554562905,0.2285742779294462,1.3034558937486695,3.8600030048314653,-0.06538144972417397,2.1045230542075872,1.6540303882823562,1.6659669752722266,0.5326129525524724,0.9018467708360485,2.1362689307517044,-0.6480246355463081,0.7979678150313219,0.010434058495094673,-0.10391188008073553,-0.9315555215226238,3.656498320463535,-0.14287070187912912,-0.30320435577832683,1.40700578874686
| 3,447
|
Mitochondrial transport
| 40
| 82
| 3.668607
| 0.000244
|
P55786,Q9NS69,O60830,P05141,Q99595,P23786,Q9Y512,P45880,Q8N4H5,O75964,P51572,Q9Y5J9,P56134,O75431,Q9UBX3,Q96EK5,O43772,Q53H12,O43615,P30536,Q6NUK1,Q9H300,Q15070,O00170,O95817,O95140,P50416,Q9Y276,P12235,P24539,P56385,Q10713,Q9P0J0,O96008,Q15388,O14925,Q8WWC4,Q9BZL1,Q99797,Q9UBE0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
516,3,4,258,9,395,274,16,20,21,404,282,405,413,31,550,286,549,543,41,425,307,53,435,438,437,316,461,208,209,337,344,87,464,353,106,363,497,502,511
|
435,1372,106,543,286,4,413,2971,2748,21,2277,437,1914,2280,438,824,464,2843,258,1163,708,2584,3248,208,1775,395,209,2847,1291,2590,41,1873,1617,1978,16,3406,2451,611,316,404,612,516,405,337,2401,344,1683,53,353,1984,3236,737,549,1742,425,2153,2378,2683,20,2103,363,550,1057,9,502,497,562,307,1028,2835,3,87,511,31,1414,1660,1032,461,1155,1768,274,282
|
0.8871862971088242,-0.008367163295788871,2.391162989421182,0.6599073521556105,1.342624187693322,4.1444590074269065,0.9454796834826562,-0.7632999174742385,-0.6029828692428588,3.5692505459608204,-0.36528796300450794,0.8871862971088242,-0.2221155959941241,-0.36528796300450794,0.8871862971088242,0.3328168814905901,0.8279499860422683,-0.6707700428550947,1.4702992943855286,0.10296527861463395,0.4341047300866308,-0.5146374427323911,-1.0827717031939503,1.7717381563510717,-0.16251400074754818,0.9742827906130651,1.7601302536193415,-0.6707700428550947,0.029135457235295485,-0.5146374427323911,3.0360255403392498,-0.20213507046424417,-0.10391188008073553,-0.24221132899251827,3.6994359897329634,-1.673164747906431,-0.44983727276622243,0.5648593382990243,1.2238621747785425,0.9599094643624182,0.5648593382990243,0.7219155083838219,0.9599094643624182,1.1425261705350076,-0.4285051553274654,1.1287949380852866,-0.12333709979746053,2.8647369895860946,1.1011786466586961,-0.24221132899251827,-1.0570912841778808,0.4174209793635682,0.6599073521556105,-0.14287070187912912,0.9164488273167519,-0.30320435577832683,-0.40730404219216754,-0.5585258554562905,3.5912373381541602,-0.28275422227728697,1.0733544735925842,0.6599073521556105,0.17528547971368946,3.8600030048314653,0.7677371814906225,0.7828838337881776,0.6442383099094389,1.2505830026120932,0.19313737866175912,-0.6480246355463081,4.276636208213452,2.5269406716164067,0.7372535957044981,3.272073939679055,-0.008367163295788871,-0.10391188008073553,0.19313737866175912,0.8428492678399792,0.12118423630495645,-0.14287070187912912,1.40700578874686,1.3685099847547963
| 3,447
|
Glycoprotein metabolic process
| 31
| 59
| 3.64474
| 0.000268
|
Q96L58,O60502,O60568,P04844,Q8TCJ2,O60476,Q9BT22,P46977,Q10472,Q99805,Q2TAA5,O15118,Q9H0U4,P35610,Q9NQX7,Q9H0U3,O43505,Q9P2E5,Q8WVQ1,Q6UW63,Q16706,O75352,Q8NAT1,Q9H3H5,Q6ZXV5,Q86YN1,P04843,Q96JB2,Q9NX62,Q9H4A6,Q7LGA3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
390,394,642,537,540,668,168,174,305,182,184,186,452,321,195,325,577,460,457,456,593,210,472,224,486,98,607,624,242,251,126
|
2620,3320,186,1710,577,668,394,642,2485,2015,3212,210,2242,607,537,2248,1430,321,2635,174,887,734,1480,1681,1078,2292,1575,305,1684,1930,1105,593,184,456,486,126,1533,98,472,540,457,689,624,390,2688,182,911,168,325,452,224,1027,251,195,242,3107,1762,460,1763
|
-0.5365115565809986,-1.241143026979425,1.8633490032538682,-0.14287070187912912,0.6126954261187706,0.4836959753352828,0.9742827906130651,0.5163809909451085,-0.471302155269236,-0.2624237136765148,-1.0316061132826644,1.7484867974571487,-0.3444696497798871,0.5648593382990243,0.6755089741541659,-0.3444696497798871,-0.027269365976897105,1.1969478078787075,-0.5365115565809986,1.9417437419205628,0.2810765284904778,0.4174209793635682,-0.04627372815783212,-0.12333709979746053,0.15734332005004562,-0.36528796300450794,-0.08459375235902318,1.2505830026120932,-0.12333709979746053,-0.2221155959941241,0.13930990831158938,0.5968202922124238,1.8859120022561358,0.8428492678399792,0.7979678150313219,2.229971341354025,-0.06538144972417397,2.4693260750464634,0.8279499860422683,0.6755089741541659,0.8428492678399792,0.46724146702283265,0.5487721681964972,0.9886001370636728,-0.5585258554562905,1.9083425678170867,0.2636616261122957,1.9967733661723275,1.1969478078787075,0.8576880629169049,1.6897278697989968,0.19313737866175912,1.5325436558776693,1.8178188702918487,1.6059037631322783,-0.8826227148684676,-0.14287070187912912,0.8428492678399792,-0.14287070187912912
| 3,447
|
Outer membrane
| 45
| 94
| 3.578237
| 0.000346
|
Q8IWA4,O43169,Q9NS69,P50402,Q9NQZ5,Q5XKP0,P09601,Q99623,Q99720,Q9UBM7,Q9Y512,P45880,Q13505,Q9BUR5,Q8N4H5,Q8N2A8,O00264,P21796,O75431,Q53H12,Q9Y6C9,P30536,Q07820,Q9NX47,Q16891,P57105,O95140,Q9NZJ7,P50416,Q86UT6,Q8WY22,Q709C8,Q9NZ45,Q9Y277,O00429,Q6UXV4,O96008,P27338,Q6NUM9,Q15388,Q9BWH2,Q9NVH1,Q9BVC6,O60313,Q9HCL2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
256,2,3,259,138,137,11,271,142,400,274,16,407,147,20,152,151,27,413,549,37,41,300,301,558,556,437,187,316,443,62,583,81,82,588,213,464,221,350,353,227,489,370,365,506
|
151,588,3246,2,365,1965,2274,413,2277,437,842,464,1161,1868,2584,11,1719,27,221,41,2814,3119,732,2790,16,259,316,612,1678,556,984,300,890,407,792,2377,2145,353,1984,3236,558,549,2213,137,350,932,213,583,1488,443,256,2378,2683,1401,152,20,1402,1112,2648,62,1947,2419,1309,1147,271,142,2268,147,370,227,2735,1313,506,862,138,3,2527,489,941,2427,301,1364,692,81,187,637,400,3147,2357,82,1155,1768,274,37
|
2.0725136772787915,0.5968202922124238,-1.0827717031939503,4.307502880587425,1.059363369451296,-0.24221132899251827,-0.36528796300450794,0.9454796834826562,-0.36528796300450794,0.8871862971088242,0.3156532797160656,0.8279499860422683,0.10296527861463395,-0.20213507046424417,-0.5146374427323911,3.804859663855004,-0.14287070187912912,3.3503698232892996,1.7015526819939406,3.0360255403392498,-0.6480246355463081,-0.9070004618348723,0.4174209793635682,-0.6254296213866243,3.6994359897329634,1.4702992943855286,1.2238621747785425,0.5648593382990243,-0.12333709979746053,0.6442383099094389,0.21089999179645574,1.2771132720400578,0.2810765284904778,0.9599094643624182,0.3668988157742944,-0.40730404219216754,-0.30320435577832683,1.1011786466586961,-0.24221132899251827,-1.0570912841778808,0.6442383099094389,0.6599073521556105,-0.3237756446783554,2.1572887559147627,1.115012567814737,0.2461611801381823,1.7250922784124725,0.6126954261187706,-0.04627372815783212,0.8724668990845809,1.4953208273418972,-0.40730404219216754,-0.5585258554562905,-0.008367163295788871,2.0725136772787915,3.5912373381541602,-0.008367163295788871,0.13930990831158938,-0.5365115565809986,2.7851863493439573,-0.2221155959941241,-0.4285051553274654,0.029135457235295485,0.12118423630495645,1.40700578874686,2.1362689307517044,-0.3444696497798871,2.1045230542075872,1.059363369451296,1.6540303882823562,-0.5806822940457038,0.029135457235295485,0.75252729309868,0.3156532797160656,2.1572887559147627,4.276636208213452,-0.471302155269236,0.7979678150313219,0.2461611801381823,-0.4285051553274654,1.2771132720400578,0.010434058495094673,0.46724146702283265,2.621124930461434,1.8633490032538682,0.5326129525524724,0.9742827906130651,-0.9315555215226238,-0.3862322082359554,2.6118073444066714,0.12118423630495645,-0.14287070187912912,1.40700578874686,3.1760717839026786
| 3,447
|
Mitochondrial transmembrane transport
| 23
| 50
| 3.573914
| 0.000352
|
P05141,O60830,Q99595,P23786,O95563,O75964,P21796,P56134,O43772,Q96NB2,O95202,Q9H2D1,P12236,P50416,Q00325,Q9Y619,Q9BSK2,P12235,P24539,P56385,Q15388,O14925,Q8WWC4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
258,4,9,395,269,21,27,405,286,296,169,46,183,316,450,329,76,208,209,337,353,106,363
|
106,543,286,4,763,2971,1669,2748,21,2277,169,269,824,464,258,1163,3248,208,183,27,395,209,2847,1617,3406,316,1233,405,337,450,353,737,966,2103,3144,363,296,9,1540,1699,76,46,1501,636,1028,1117,1660,1032,2180,329
|
2.391162989421182,0.6599073521556105,1.342624187693322,4.1444590074269065,0.3838188193188344,-0.7632999174742385,-0.12333709979746053,-0.6029828692428588,3.5692505459608204,-0.36528796300450794,1.9858304188448097,1.40700578874686,0.3328168814905901,0.8279499860422683,1.4702992943855286,0.10296527861463395,-1.0827717031939503,1.7717381563510717,1.8859120022561358,3.3503698232892996,0.9742827906130651,1.7601302536193415,-0.6707700428550947,-0.10391188008073553,-1.673164747906431,1.2238621747785425,0.06624331600225977,0.9599094643624182,1.1425261705350076,0.8576880629169049,1.1011786466586961,0.4174209793635682,0.2285742779294462,-0.28275422227728697,-0.9315555215226238,1.0733544735925842,1.3034558937486695,3.8600030048314653,-0.06538144972417397,-0.12333709979746053,2.6948832866620145,2.9513000228072084,-0.04627372815783212,0.5326129525524724,0.19313737866175912,0.13930990831158938,-0.10391188008073553,0.19313737866175912,-0.30320435577832683,1.1834170961274035
| 3,447
|
Endoplasmic reticulum organization
| 25
| 44
| 3.5216
| 0.000429
|
Q8N4V1,Q15042,P49069,O95197,Q00765,O43681,Q15629,Q9NQC3,Q9NVV0,Q96A33,P46379,Q12981,Q15041,Q9P2W9,P61026,P57088,P61619,Q8NHH9,O00429,Q8N5M9,A0FGR8,Q15363,P49257,Q9P0I2,Q9NPA0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
5,649,276,23,280,531,33,35,563,178,179,439,311,68,580,73,336,339,588,85,587,222,611,626,253
|
587,588,1810,864,1418,531,2387,1913,23,2626,179,276,611,73,580,336,280,1174,439,1890,311,649,222,33,1835,1348,5,85,855,1453,339,178,2734,1360,837,2167,1088,253,35,563,692,626,2529,68
|
0.5968202922124238,0.5968202922124238,-0.1822683354853108,0.29840678518812824,-0.027269365976897105,0.6910437992675935,-0.4285051553274654,-0.2221155959941241,3.4195663235378624,-0.5365115565809986,1.9195087103543416,1.3942178014247664,0.5648593382990243,2.713109541828266,0.6126954261187706,1.156206673163405,1.3813859753747217,0.10296527861463395,0.8871862971088242,-0.20213507046424417,1.237246593120908,0.5163809909451085,1.7015526819939406,3.216350650152123,-0.1822683354853108,0.010434058495094673,4.040872839878629,2.555433683915995,0.3156532797160656,-0.027269365976897105,1.1425261705350076,1.9306423672509032,-0.5806822940457038,0.010434058495094673,0.3328168814905901,-0.30320435577832683,0.15734332005004562,1.5201769173547421,3.1922316667835537,0.6442383099094389,0.46724146702283265,0.5487721681964972,-0.471302155269236,2.7583110565843194
| 3,447
|
Intrinsic component of mitochondrial inner membrane
| 22
| 30
| 3.509189
| 0.000449
|
O60830,Q99595,Q5XKP0,Q9HC21,Q9Y512,Q13505,O95563,Q9BUR5,O75880,Q9Y2R0,O75431,Q53H12,Q96NB2,Q9H9P8,Q15070,Q00325,Q6UXV4,O43819,Q9H3K2,Q9NVH1,O14925,Q16134
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
4,9,137,143,274,407,269,147,520,17,413,549,296,433,53,450,213,340,225,489,106,504
|
106,340,4,413,520,269,3119,748,450,407,53,504,558,549,137,213,966,296,9,147,225,636,433,143,489,1364,1658,17,2180,274
|
2.391162989421182,1.1287949380852866,4.1444590074269065,0.9454796834826562,0.7065124420438686,1.40700578874686,-0.9070004618348723,0.4006592727447067,0.8576880629169049,0.9599094643624182,2.8647369895860946,0.75252729309868,0.6442383099094389,0.6599073521556105,2.1572887559147627,1.7250922784124725,0.2285742779294462,1.3034558937486695,3.8600030048314653,2.1045230542075872,1.6659669752722266,0.5326129525524724,0.9018467708360485,2.1362689307517044,0.7979678150313219,0.010434058495094673,-0.10391188008073553,3.656498320463535,-0.30320435577832683,1.40700578874686
| 3,447
|
Parkinsons disease
| 17
| 57
| 3.494582
| 0.000475
|
P14406,P05141,P42574,O43676,Q9UDW1,P45880,P12235,P03886,P24539,Q9Y277,O75438,Q9Y6M9,P12236,O14949,P13073,P00403,P21796
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
1,258,229,8,14,16,208,146,209,82,181,86,183,24,89,245,27
|
2182,1597,24,8,2272,1327,382,706,181,2117,2748,453,3383,2390,568,245,146,1128,258,1163,578,802,879,208,183,89,1,1228,922,3336,508,27,270,1720,981,209,2847,3345,2495,1009,1617,229,16,1196,3406,3214,484,1980,2401,1780,3142,1631,2688,432,14,82,86
|
-0.3237756446783554,-0.10391188008073553,3.411935775289236,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,-0.6029828692428588,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,1.4702992943855286,0.10296527861463395,0.6126954261187706,0.349898446135214,0.2810765284904778,1.7717381563510717,1.8859120022561358,2.517396848234407,4.313649129144161,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,3.3503698232892996,1.40700578874686,-0.14287070187912912,0.21089999179645574,1.7601302536193415,-0.6707700428550947,-1.3232487120310719,-0.471302155269236,0.19313737866175912,-0.10391188008073553,1.6420560339548476,3.6994359897329634,0.0846519922036011,-1.673164747906431,-1.0316061132826644,0.7979678150313219,-0.24221132899251827,-0.4285051553274654,-0.16251400074754818,-0.9315555215226238,-0.10391188008073553,-0.5585258554562905,0.9018467708360485,3.7489696574923244,2.6118073444066714,2.5364613381868493
| 3,447
|
Glycoprotein biosynthetic process
| 29
| 51
| 3.493294
| 0.000477
|
Q96L58,O60502,O60568,P04844,Q8TCJ2,O60476,Q9BT22,P46977,Q10472,Q99805,Q2TAA5,O15118,P35610,Q9NQX7,Q9H0U3,O43505,Q9P2E5,Q8WVQ1,Q6UW63,Q16706,O75352,Q8NAT1,Q9H3H5,Q6ZXV5,Q86YN1,P04843,Q96JB2,Q9H4A6,Q7LGA3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
390,394,642,537,540,668,168,174,305,182,184,186,321,195,325,577,460,457,456,593,210,472,224,486,98,607,624,251,126
|
2620,186,1710,577,668,394,642,2485,2015,3212,210,2242,607,537,1430,321,2635,174,887,1480,1681,1078,2292,1575,305,1684,1930,593,184,456,486,126,1533,98,472,540,457,689,624,390,182,168,325,224,1027,251,195,3107,1762,460,1763
|
-0.5365115565809986,1.8633490032538682,-0.14287070187912912,0.6126954261187706,0.4836959753352828,0.9742827906130651,0.5163809909451085,-0.471302155269236,-0.2624237136765148,-1.0316061132826644,1.7484867974571487,-0.3444696497798871,0.5648593382990243,0.6755089741541659,-0.027269365976897105,1.1969478078787075,-0.5365115565809986,1.9417437419205628,0.2810765284904778,-0.04627372815783212,-0.12333709979746053,0.15734332005004562,-0.36528796300450794,-0.08459375235902318,1.2505830026120932,-0.12333709979746053,-0.2221155959941241,0.5968202922124238,1.8859120022561358,0.8428492678399792,0.7979678150313219,2.229971341354025,-0.06538144972417397,2.4693260750464634,0.8279499860422683,0.6755089741541659,0.8428492678399792,0.46724146702283265,0.5487721681964972,0.9886001370636728,1.9083425678170867,1.9967733661723275,1.1969478078787075,1.6897278697989968,0.19313737866175912,1.5325436558776693,1.8178188702918487,-0.8826227148684676,-0.14287070187912912,0.8428492678399792,-0.14287070187912912
| 3,447
|
Protein targeting to mitochondrion
| 23
| 46
| 3.477984
| 0.000505
|
P55786,Q9NS69,O60830,Q99595,Q9Y512,Q8N4H5,P51572,Q9Y5J9,Q53H12,O43615,P30536,Q9H300,O00170,O95817,O95140,Q10713,Q9P0J0,O96008,Q15388,O14925,Q9BZL1,Q99797,Q9UBE0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
516,3,4,9,274,20,404,282,549,543,41,307,435,438,437,344,87,464,353,106,497,502,511
|
435,1372,106,543,4,2971,2277,437,1914,2280,438,824,464,708,3248,1775,41,1873,611,404,516,2401,344,1683,353,1984,737,549,1742,2153,20,2103,9,502,497,562,307,1028,3,87,511,1414,1155,1768,274,282
|
0.8871862971088242,-0.008367163295788871,2.391162989421182,0.6599073521556105,4.1444590074269065,-0.7632999174742385,-0.36528796300450794,0.8871862971088242,-0.2221155959941241,-0.36528796300450794,0.8871862971088242,0.3328168814905901,0.8279499860422683,0.4341047300866308,-1.0827717031939503,-0.16251400074754818,3.0360255403392498,-0.20213507046424417,0.5648593382990243,0.9599094643624182,0.7219155083838219,-0.4285051553274654,1.1287949380852866,-0.12333709979746053,1.1011786466586961,-0.24221132899251827,0.4174209793635682,0.6599073521556105,-0.14287070187912912,-0.30320435577832683,3.5912373381541602,-0.28275422227728697,3.8600030048314653,0.7677371814906225,0.7828838337881776,0.6442383099094389,1.2505830026120932,0.19313737866175912,4.276636208213452,2.5269406716164067,0.7372535957044981,-0.008367163295788871,0.12118423630495645,-0.14287070187912912,1.40700578874686,1.3685099847547963
| 3,447
|
Anion transmembrane transporter activity
| 25
| 47
| 3.476443
| 0.000508
|
P05141,P0CG08,Q9Y6M7,Q9HC21,P45880,O95563,P21796,Q9UBX3,Q14728,Q96NB2,Q6NUK1,Q9H2D1,Q6KCM7,P12236,P30825,Q8TB61,P51790,Q4KMQ2,P55011,Q9Y619,Q86VD7,P12235,Q9Y277,O43808,P53985
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
258,514,530,143,16,269,27,31,417,296,425,46,306,183,310,64,448,323,449,329,332,208,82,347,237
|
1909,666,531,347,1669,269,258,1915,514,844,208,183,27,310,1231,661,16,448,749,1233,237,449,829,417,1018,323,306,3434,2762,425,1450,332,64,1143,296,1699,912,46,1501,636,143,31,1660,82,329,3273,530
|
-0.2221155959941241,0.4836959753352828,0.6910437992675935,1.115012567814737,-0.12333709979746053,1.40700578874686,1.4702992943855286,-0.2221155959941241,0.7219155083838219,0.3156532797160656,1.7717381563510717,1.8859120022561358,3.3503698232892996,1.237246593120908,0.06624331600225977,0.500075572431892,3.6994359897329634,0.8576880629169049,0.4006592727447067,0.06624331600225977,1.6179929845170453,0.8576880629169049,0.3328168814905901,0.9454796834826562,0.19313737866175912,1.1969478078787075,1.2505830026120932,-2.5135956035021803,-0.6029828692428588,0.9164488273167519,-0.027269365976897105,1.1698368489882653,2.776248153122407,0.12118423630495645,1.3034558937486695,-0.12333709979746053,0.2636616261122957,2.9513000228072084,-0.04627372815783212,0.5326129525524724,2.1362689307517044,3.272073939679055,-0.10391188008073553,2.6118073444066714,1.1834170961274035,-1.1086506296557357,0.7065124420438686
| 3,447
|
Organic anion transmembrane transporter activity
| 16
| 32
| 3.426817
| 0.000611
|
Q8TB61,Q14728,P05141,Q9Y619,Q96NB2,Q86VD7,P53985,Q9HC21,Q9H2D1,P12235,O95563,Q6KCM7,P12236,P30825,O43808,Q9UBX3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,417,258,329,296,332,237,143,46,208,269,306,183,310,347,31
|
666,347,1669,269,258,1915,844,208,183,310,1231,661,1233,237,829,417,1018,306,425,1450,332,64,296,1699,46,1501,636,143,31,1660,329,530
|
0.4836959753352828,1.115012567814737,-0.12333709979746053,1.40700578874686,1.4702992943855286,-0.2221155959941241,0.3156532797160656,1.7717381563510717,1.8859120022561358,1.237246593120908,0.06624331600225977,0.500075572431892,0.06624331600225977,1.6179929845170453,0.3328168814905901,0.9454796834826562,0.19313737866175912,1.2505830026120932,0.9164488273167519,-0.027269365976897105,1.1698368489882653,2.776248153122407,1.3034558937486695,-0.12333709979746053,2.9513000228072084,-0.04627372815783212,0.5326129525524724,2.1362689307517044,3.272073939679055,-0.10391188008073553,1.1834170961274035,0.7065124420438686
| 3,447
|
Sphingolipid metabolic process
| 16
| 31
| 3.363835
| 0.000769
|
O95470,P04062,P07602,Q9P035,P17900,Q06136,Q96G23,Q6Y1H2,P50897,O15269,Q99805,Q13510,Q16880,Q9NZJ7,P27544,Q9NZ01
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,97,166,134,198,200,103,172,77,239,182,121,122,187,61,127
|
239,628,65,97,1225,2327,166,3428,866,198,2999,1290,61,1264,77,2206,200,1683,121,122,549,172,289,103,2829,182,692,127,187,134,2529
|
1.6059037631322783,0.5326129525524724,2.767289755156624,2.4693260750464634,0.06624331600225977,-0.3862322082359554,2.007685211650335,-2.333607799065281,0.29840678518812824,1.794848233650915,-0.7868309696564781,0.029135457235295485,2.7851863493439573,0.04773817048517167,2.685738533107751,-0.3237756446783554,1.794848233650915,-0.12333709979746053,2.270900210400071,2.270900210400071,0.6599073521556105,1.9638504485042398,1.3296137106483024,2.410850833556328,-0.6480246355463081,1.9083425678170867,0.46724146702283265,2.229971341354025,1.8633490032538682,2.178194878551719,-0.471302155269236
| 3,447
|
ER-Golgi transport
| 15
| 55
| 3.361938
| 0.000774
|
P24390,O95249,Q9P2W9,O15498,O43731,O95070,Q9NR31,Q969X5,Q9HCU5,P49069,P49755,O95197,P51572,Q15363,Q9Y282
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
0,66,68,197,6,171,206,429,441,276,343,23,404,222,26
|
780,864,197,2841,1601,6,2624,1064,1913,171,23,66,865,1127,2125,0,1337,618,276,611,343,404,2498,1521,2453,2030,953,711,734,888,439,1733,222,2040,715,1835,1448,962,2216,1241,1994,3036,429,3060,441,1853,206,68,2318,1661,26,1592,586,1063,1157
|
0.3668988157742944,0.29840678518812824,1.794848233650915,-0.6707700428550947,-0.10391188008073553,3.9547704783957736,-0.5365115565809986,0.15734332005004562,-0.2221155959941241,1.9638504485042398,3.4195663235378624,2.7583110565843194,0.29840678518812824,0.12118423630495645,-0.30320435577832683,4.529155521859711,0.010434058495094673,0.5487721681964972,1.3942178014247664,0.5648593382990243,1.1287949380852866,0.9599094643624182,-0.471302155269236,-0.06538144972417397,-0.44983727276622243,-0.2624237136765148,0.2285742779294462,0.4341047300866308,0.4174209793635682,0.2810765284904778,0.8871862971088242,-0.14287070187912912,1.7015526819939406,-0.2624237136765148,0.4341047300866308,-0.1822683354853108,-0.027269365976897105,0.2285742779294462,-0.3237756446783554,0.06624331600225977,-0.24221132899251827,-0.8105262504581725,0.9018467708360485,-0.8343882553406996,0.8871862971088242,-0.1822683354853108,1.7833107392720506,2.7583110565843194,-0.36528796300450794,-0.10391188008073553,3.396631569290751,-0.08459375235902318,0.6126954261187706,0.17528547971368946,0.12118423630495645
| 3,447
|
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.