term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Growth factor binding
| 7
| 15
| 2.66069
| 0.007798
|
O14786,Q99523,P29317,Q15375,O00560,P11717,Q92896
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
99,45,178,119,151,31,63
|
151,99,246,569,31,1929,2580,978,178,540,2819,119,63,45,398
|
1.4567344646526146,2.308023112336245,0.8548811891149231,0.3883074039088583,4.393795198319631,-0.16899212443771205,-0.41292781072703233,0.16647131175699767,1.162570531532433,0.412471861925284,-0.5247469164830378,1.8757230653380457,3.3469394788706537,3.9016924241886017,0.5790643592485345
| 3,447
|
Collagen containing extracellular matrix
| 7
| 33
| 2.658309
| 0.007853
|
P19022,Q08380,P07602,P07942,P53634,P10909,Q5SZK8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
110,16,15,146,20,58,92
|
1526,505,970,1616,2462,15,146,3116,3311,58,1709,1394,860,110,2010,2580,671,606,478,639,1784,3312,376,2660,20,2595,16,408,782,185,92,3166,2750
|
-0.037732006077157064,0.43654311105882554,0.16647131175699767,-0.06375283048767906,-0.3578263417200354,4.95230803704758,1.4977414359476033,-0.7259155280154393,-0.9957915972367293,3.4892019402118737,-0.08988792448924106,0.013971984461395193,0.21646479318514736,2.0100448717400776,-0.19559772347892793,-0.41292781072703233,0.3152452291356413,0.36404879012622693,0.48440969406177936,0.33969505804727207,-0.11613860568977677,-0.9957915972367293,0.6025084155120215,-0.44067800799054646,4.872739253374519,-0.41292781072703233,4.95230803704758,0.5555333123030265,0.26605328440668863,1.1194802025914279,2.4526072090297046,-0.7552547701634187,-0.46856343097646624
| 3,447
|
Glycolipid catabolic process
| 6
| 8
| 2.65738
| 0.007875
|
P17900,Q99519,P04066,P06280,P07686,P06865
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,75,11,12,46,14
|
114,11,12,14,46,4,1189,75
|
1.952786157251336,5.238210069294953,5.096383797522485,4.991829849894577,3.8867761966938223,5.796784418092093,0.09070253409564899,3.0047879739765255
| 3,447
|
Ceramide catabolic process
| 6
| 8
| 2.656871
| 0.007887
|
P17900,Q99519,Q13510,P06280,P07686,P06865
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,75,43,12,46,14
|
114,12,14,46,4,1189,43,75
|
1.952786157251336,5.096383797522485,4.991829849894577,3.8867761966938223,5.796784418092093,0.09070253409564899,3.9610928617452967,3.0047879739765255
| 3,447
|
Neuromuscular process controlling balance
| 7
| 13
| 2.654295
| 0.007947
|
P07196,P05067,P17900,O14773,Q15334,P07686,P10253
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
310,66,4,10,206,46,59
|
10,595,66,310,46,59,634,4,816,916,206,1882,346
|
5.276511437873593,0.36404879012622693,3.185852181395418,0.6954312126789955,3.8867761966938223,3.426283702043037,0.33969505804727207,5.796784418092093,0.24130912809996094,0.19151921531853922,1.032454143437075,-0.14250621643165773,0.6491388771216718
| 3,447
|
Cell cell adhesion via plasma membrane adhesion molecules
| 9
| 18
| 2.637905
| 0.008342
|
P35613,Q14574,Q92845,P78310,Q14126,P19022,Q9BY67,P98194,Q13740
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,69,333,136,137,110,175,298,154
|
2569,804,2257,507,2085,110,160,136,298,154,137,69,1485,2130,333,175,1982,350
|
-0.41292781072703233,0.24130912809996094,-0.2761470099076228,0.43654311105882554,-0.22232443406475605,2.0100448717400776,1.3739783978655824,1.6193233192302938,0.7184525652536403,1.4154814144632912,1.6193233192302938,3.1040662322378125,-0.011824157758994824,-0.22232443406475605,0.6723269112207332,1.1840120855874656,-0.16899212443771205,0.6491388771216718
| 3,447
|
Blindness
| 15
| 76
| 2.634931
| 0.008415
|
O43505,Q8NHS3,P16278,P17900,O96000,P06865,P07686,P07602,Q9NZ08,P51798,Q5SZK8,P50897,Q15555,O43676,P21359
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,195,35,4,286,14,46,15,278,209,92,21,316,219,220
|
1313,1155,3256,3036,2571,65,219,899,1767,2388,805,2078,1842,1321,2810,286,2459,2006,3181,1705,14,15,46,1925,35,4,2163,1246,220,2011,3369,3185,2866,2524,1937,1332,2467,815,2018,1261,3214,2962,21,209,1627,1405,3365,449,1475,2402,1637,1479,379,316,92,1802,2608,2206,1206,195,2129,1064,2041,3378,657,3225,1898,949,3108,351,278,2750,3277,1830,3352,2325
|
0.03965766766041974,0.09070253409564899,-0.9043423207096438,-0.6676978506562085,-0.41292781072703233,3.2021083972634283,0.944268201707387,0.19151921531853922,-0.11613860568977677,-0.33047177855621607,0.24130912809996094,-0.22232443406475605,-0.14250621643165773,0.03965766766041974,-0.5247469164830378,0.7413917409113739,-0.3578263417200354,-0.19559772347892793,-0.7847504591189078,-0.08988792448924106,4.991829849894577,4.95230803704758,3.8867761966938223,-0.16899212443771205,4.165756851456292,5.796784418092093,-0.2491737041569007,0.06523411656369492,0.944268201707387,-0.19559772347892793,-1.2799168876410205,-0.7847504591189078,-0.5530485515520936,-0.38531114273962846,-0.16899212443771205,0.03965766766041974,-0.3578263417200354,0.24130912809996094,-0.19559772347892793,0.06523411656369492,-0.8144047886641401,-0.6100808230827668,4.832688203866245,1.0105179663695107,-0.06375283048767906,0.013971984461395193,-1.2475813324366078,0.5082068465574456,-0.011824157758994824,-0.33047177855621607,-0.06375283048767906,-0.011824157758994824,0.6025084155120215,0.6954312126789955,2.4526072090297046,-0.11613860568977677,-0.41292781072703233,-0.2491737041569007,0.09070253409564899,1.0761096734158762,-0.22232443406475605,0.14131998091565823,-0.19559772347892793,-1.3124535957086996,0.33969505804727207,-0.8144047886641401,-0.14250621643165773,0.19151921531853922,-0.6967305875166148,0.6491388771216718,0.7870265918459427,-0.46856343097646624,-0.9043423207096438,-0.11613860568977677,-1.1201939880656602,-0.2761470099076228
| 3,447
|
Alcohol biosynthetic process
| 12
| 38
| 2.632547
| 0.008475
|
Q15800,Q15125,Q15392,Q13510,P04062,P00374,Q9UBM7,P53602,P54646,Q14739,O76062,Q13131
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
344,68,9,43,114,117,86,279,280,87,90,377
|
2857,854,1158,806,2005,90,1844,117,3077,114,2265,2086,670,2518,1541,1254,2712,2397,2714,1721,279,280,609,2822,377,43,2774,87,68,1483,9,2969,344,2195,431,3024,2628,86
|
-0.5530485515520936,0.21646479318514736,0.09070253409564899,0.24130912809996094,-0.19559772347892793,2.506111945225677,-0.14250621643165773,1.8950668629102478,-0.6967305875166148,1.952786157251336,-0.2761470099076228,-0.22232443406475605,0.3152452291356413,-0.38531114273962846,-0.037732006077157064,0.06523411656369492,-0.46856343097646624,-0.33047177855621607,-0.46856343097646624,-0.08988792448924106,0.764249500072063,0.764249500072063,0.36404879012622693,-0.5247469164830378,0.6025084155120215,3.9610928617452967,-0.49658581124515616,2.5415711073347276,3.120491344892983,-0.011824157758994824,5.327333042658442,-0.6100808230827668,0.6491388771216718,-0.2491737041569007,0.5319144280730378,-0.6388152651515875,-0.41292781072703233,2.5768641425022323
| 3,447
|
Protein processing
| 7
| 48
| 2.629992
| 0.008539
|
O75844,P42892,O75976,O75503,Q15392,Q92542,Q92896
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
189,5,39,8,9,50,63
|
1607,1529,2757,8,189,39,2574,2459,2647,2462,2084,2519,2520,1109,2707,490,2656,5,3121,774,608,1947,2028,3157,205,2541,9,2828,1349,2290,1644,552,2983,50,63,1007,1810,2892,1975,2986,1076,1144,2232,2311,3400,533,1150,3176
|
-0.06375283048767906,-0.037732006077157064,-0.49658581124515616,5.390468925074161,1.0978302599790803,4.107784534784334,-0.41292781072703233,-0.3578263417200354,-0.44067800799054646,-0.3578263417200354,-0.22232443406475605,-0.38531114273962846,-0.38531114273962846,0.11606410191198446,-0.46856343097646624,0.460522082895191,-0.44067800799054646,5.626549900164905,-0.7259155280154393,0.26605328440668863,0.36404879012622693,-0.16899212443771205,-0.19559772347892793,-0.7552547701634187,1.032454143437075,-0.38531114273962846,5.327333042658442,-0.5247469164830378,0.03965766766041974,-0.2761470099076228,-0.06375283048767906,0.412471861925284,-0.6100808230827668,3.736124836573613,3.3469394788706537,0.16647131175699767,-0.11613860568977677,-0.5530485515520936,-0.16899212443771205,-0.6100808230827668,0.14131998091565823,0.11606410191198446,-0.2491737041569007,-0.2761470099076228,-1.4781383235442953,0.43654311105882554,0.11606410191198446,-0.7552547701634187
| 3,447
|
Trans golgi network membrane
| 7
| 25
| 2.62708
| 0.008612
|
Q7Z6M1,P05067,Q9UID3,Q15334,P20645,Q9NX62,P11717
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
33,66,307,206,142,94,31
|
1763,702,1695,1917,2904,66,357,31,142,1113,3046,2964,1628,2666,1121,1047,2486,206,1569,33,1140,1364,1589,94,307
|
-0.11613860568977677,0.290698308478738,-0.08988792448924106,-0.16899212443771205,-0.5814925595785796,3.185852181395418,0.625866314583955,4.393795198319631,1.5587987614920094,0.11606410191198446,-0.6676978506562085,-0.6100808230827668,-0.06375283048767906,-0.44067800799054646,0.11606410191198446,0.14131998091565823,-0.3578263417200354,1.032454143437075,-0.037732006077157064,4.266269685759162,0.11606410191198446,0.03965766766041974,-0.037732006077157064,2.416723651268817,0.7184525652536403
| 3,447
|
membrane trafficking regulatory protein
| 6
| 21
| 2.626983
| 0.008615
|
P11279,Q15334,O43731,O00560,Q14108,Q8WTV0
|
Functions
|
Panther Protein class
|
panther_protein_class
|
41,206,80,151,26,62
|
2075,896,151,80,230,2457,41,2268,26,206,2543,62,2614,2551,744,1582,1509,2308,841,2375,3109
|
-0.22232443406475605,0.19151921531853922,1.4567344646526146,2.750906555502383,0.899727495712953,-0.3578263417200354,4.005368888045156,-0.2761470099076228,4.7385298944612435,1.032454143437075,-0.38531114273962846,3.3469394788706537,-0.41292781072703233,-0.38531114273962846,0.290698308478738,-0.037732006077157064,-0.011824157758994824,-0.2761470099076228,0.24130912809996094,-0.3032458564235702,-0.6967305875166148
| 3,447
|
Cardiomegaly
| 8
| 36
| 2.621852
| 0.008745
|
P04066,Q99519,P07686,P04062,Q14739,P54802,P10253,Q07021
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
11,75,46,114,87,25,59,191
|
758,1029,2809,114,11,46,59,193,1773,1928,1710,767,3084,2866,1856,2584,3325,676,25,3047,2664,191,1791,3370,87,930,1735,3317,1001,1427,2691,75,3225,2562,1228,3148
|
0.26605328440668863,0.14131998091565823,-0.5247469164830378,1.952786157251336,5.238210069294953,3.8867761966938223,3.426283702043037,1.0761096734158762,-0.11613860568977677,-0.16899212443771205,-0.08988792448924106,0.26605328440668863,-0.6967305875166148,-0.5530485515520936,-0.14250621643165773,-0.41292781072703233,-1.0266222601373636,0.3152452291356413,4.7385298944612435,-0.6676978506562085,-0.44067800799054646,1.0978302599790803,-0.11613860568977677,-1.2799168876410205,2.5415711073347276,0.19151921531853922,-0.08988792448924106,-0.9957915972367293,0.16647131175699767,0.013971984461395193,-0.44067800799054646,3.0047879739765255,-0.8144047886641401,-0.38531114273962846,0.09070253409564899,-0.7259155280154393
| 3,447
|
Secretory granule
| 49
| 239
| 2.620714
| 0.008775
|
P15586,Q93050,P17900,P42892,O00584,Q8NBM8,Q9NV96,P78310,P04066,P06280,P06865,Q08380,P07602,P67870,P53634,O00560,Q9BTY2,P61916,O00754,P11717,P35613,P16278,Q92820,P11279,Q13510,Q9NQX7,P07686,P10619,P42785,Q92542,P27105,O75874,P10909,P10253,Q08722,P05067,P51790,Q99519,P31949,O15400,P10321,Q92520,Q7L576,Q9UQB8,O15260,Q13442,Q9UEU0,Q9Y5K8,Q6IAA8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,257,4,5,6,134,271,136,11,12,14,16,15,274,20,151,24,28,30,31,160,35,42,41,43,44,46,47,49,50,53,55,58,59,194,66,70,75,203,210,83,213,223,97,98,227,105,245,238
|
1837,2075,802,2149,1094,2151,151,1525,6,30,2002,98,210,1026,1764,1027,2154,667,2385,2642,597,857,55,632,1455,1102,3077,705,11,2516,970,66,12,602,1772,14,2462,668,1167,15,46,764,1168,905,1034,3341,1104,3079,1461,2335,1926,59,83,47,2910,58,2391,1105,41,31,2161,1106,2577,1617,1462,1170,404,1709,1928,1,1710,35,2519,2520,489,4,860,444,1542,1463,1464,2009,2010,426,1246,1775,1853,53,671,1933,2466,713,2014,1714,606,203,1546,478,981,490,160,1857,3445,2269,982,1037,2469,1257,49,5,3250,1548,479,675,1940,3312,865,641,3044,2343,70,481,1721,1941,20,2275,1265,1407,2475,819,1867,2662,1944,28,1730,3012,274,1473,2478,136,2593,576,2187,1189,2027,16,194,3156,3241,3052,825,1792,330,227,518,43,2598,2191,452,2538,649,549,3192,730,1346,3420,2543,1485,994,432,521,651,238,3193,1881,1420,223,1058,881,832,1001,134,2213,3426,1965,739,2614,412,213,50,42,257,2783,2300,622,3136,1434,1813,837,75,2496,2986,1664,461,24,1588,1589,1300,414,467,284,1509,1511,336,1303,2234,44,1516,486,271,2898,2750,2375,105,2067,2146,3293,1522,3032,1087,97,2803,322,420,2073,801,245,1022,1382
|
-0.14250621643165773,-0.22232443406475605,0.24130912809996094,-0.2491737041569007,0.11606410191198446,-0.2491737041569007,1.4567344646526146,-0.037732006077157064,5.503041426277297,4.49169826573745,-0.19559772347892793,2.326250857937109,0.9885086777190719,0.14131998091565823,-0.11613860568977677,0.14131998091565823,-0.2491737041569007,0.3152452291356413,-0.33047177855621607,-0.44067800799054646,0.36404879012622693,0.21646479318514736,3.5826739461700328,0.33969505804727207,-0.011824157758994824,0.11606410191198446,-0.6967305875166148,0.290698308478738,5.238210069294953,-0.38531114273962846,0.16647131175699767,3.185852181395418,5.096383797522485,0.36404879012622693,-0.11613860568977677,4.991829849894577,-0.3578263417200354,0.3152452291356413,0.09070253409564899,4.95230803704758,3.8867761966938223,0.26605328440668863,0.09070253409564899,0.19151921531853922,0.14131998091565823,-1.0888207132458592,0.11606410191198446,-0.6967305875166148,-0.011824157758994824,-0.3032458564235702,-0.16899212443771205,3.426283702043037,2.699110242674545,3.8568635354262555,-0.5814925595785796,3.4892019402118737,-0.33047177855621607,0.11606410191198446,4.005368888045156,4.393795198319631,-0.2491737041569007,0.11606410191198446,-0.41292781072703233,-0.06375283048767906,-0.011824157758994824,0.09070253409564899,0.5555333123030265,-0.08988792448924106,-0.16899212443771205,6.058298299026471,-0.08988792448924106,4.165756851456292,-0.38531114273962846,-0.38531114273962846,0.460522082895191,5.796784418092093,0.21646479318514736,0.5082068465574456,-0.037732006077157064,-0.011824157758994824,-0.011824157758994824,-0.19559772347892793,-0.19559772347892793,0.5319144280730378,0.06523411656369492,-0.11613860568977677,-0.14250621643165773,3.6443989474477476,0.3152452291356413,-0.16899212443771205,-0.3578263417200354,0.290698308478738,-0.19559772347892793,-0.08988792448924106,0.36404879012622693,1.032454143437075,-0.037732006077157064,0.48440969406177936,0.16647131175699767,0.460522082895191,1.3739783978655824,-0.14250621643165773,-15.9784026580102,-0.2761470099076228,0.16647131175699767,0.14131998091565823,-0.3578263417200354,0.06523411656369492,3.7816081165133633,5.626549900164905,-0.8741983970490654,-0.037732006077157064,0.48440969406177936,0.3152452291356413,-0.16899212443771205,-0.9957915972367293,0.21646479318514736,0.33969505804727207,-0.6676978506562085,-0.3032458564235702,3.0545841549970008,0.48440969406177936,-0.08988792448924106,-0.16899212443771205,4.872739253374519,-0.2761470099076228,0.06523411656369492,0.013971984461395193,-0.3578263417200354,0.24130912809996094,-0.14250621643165773,-0.44067800799054646,-0.16899212443771205,4.602257829733616,-0.08988792448924106,-0.6388152651515875,0.7870265918459427,-0.011824157758994824,-0.3578263417200354,1.6193233192302938,-0.41292781072703233,0.3883074039088583,-0.2491737041569007,0.09070253409564899,-0.19559772347892793,4.95230803704758,1.0761096734158762,-0.7552547701634187,-0.8442200027409706,-0.6676978506562085,0.24130912809996094,-0.11613860568977677,0.6723269112207332,0.9220357095144189,0.43654311105882554,3.9610928617452967,-0.41292781072703233,-0.2491737041569007,0.5082068465574456,-0.38531114273962846,0.33969505804727207,0.412471861925284,-0.7847504591189078,0.290698308478738,0.03965766766041974,-1.8599003564047882,-0.38531114273962846,-0.011824157758994824,0.16647131175699767,0.5319144280730378,0.43654311105882554,0.33969505804727207,0.8773428842135269,-0.7847504591189078,-0.14250621643165773,0.013971984461395193,0.944268201707387,0.14131998091565823,0.21646479318514736,0.24130912809996094,0.16647131175699767,1.6393818573898824,-0.2491737041569007,-2.0410879278253518,-0.16899212443771205,0.290698308478738,-0.41292781072703233,0.5555333123030265,0.9885086777190719,3.736124836573613,4.005368888045156,0.8323417145063771,-0.49658581124515616,-0.2761470099076228,0.36404879012622693,-0.7259155280154393,0.013971984461395193,-0.11613860568977677,0.24130912809996094,3.0047879739765255,-0.3578263417200354,-0.6100808230827668,-0.06375283048767906,0.5082068465574456,4.752042300962526,-0.037732006077157064,-0.037732006077157064,0.06523411656369492,0.5555333123030265,0.5082068465574456,0.764249500072063,-0.011824157758994824,-0.011824157758994824,0.6723269112207332,0.06523411656369492,-0.2491737041569007,3.9610928617452967,-0.011824157758994824,0.48440969406177936,0.80972375426467,-0.5530485515520936,-0.46856343097646624,-0.3032458564235702,2.179150607376429,-0.19559772347892793,-0.22232443406475605,-0.9346541779980903,-0.011824157758994824,-0.6388152651515875,0.14131998091565823,2.3444338300023935,-0.49658581124515616,0.6954312126789955,0.5555333123030265,-0.19559772347892793,0.26605328440668863,0.8773428842135269,0.16647131175699767,0.03965766766041974
| 3,447
|
Abnormality of corneal stroma
| 6
| 12
| 2.618746
| 0.008825
|
O43505,P16278,P01130,Q13510,P10619,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,35,73,43,47,114
|
65,2005,73,114,47,35,405,2523,289,43,157,996
|
3.2021083972634283,-0.19559772347892793,3.0214219227005468,1.952786157251336,3.8568635354262555,4.165756851456292,0.5555333123030265,-0.38531114273962846,0.7413917409113739,3.9610928617452967,1.3947613988096557,0.16647131175699767
| 3,447
|
Smooth muscle cell migration
| 6
| 13
| 2.617063
| 0.008869
|
Q9UIW2,O14786,P31949,O94813,P09493,Q07954
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
225,99,203,84,236,60
|
99,84,236,978,203,1334,1944,60,275,2485,1433,2223,225
|
2.308023112336245,2.6294966021683392,0.8773428842135269,0.16647131175699767,1.032454143437075,0.03965766766041974,-0.16899212443771205,3.362871077444676,0.7870265918459427,-0.3578263417200354,0.013971984461395193,-0.2491737041569007,0.944268201707387
| 3,447
|
Sodium ion transmembrane transport
| 10
| 23
| 2.605977
| 0.009161
|
Q12959,P08195,O14745,Q6P4Q7,P55011,P27105,P05026,P46934,P54709,Q96PU5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
408,161,338,365,491,53,183,184,221,349
|
338,1027,1847,1459,183,161,1173,53,1778,184,1040,1863,221,491,545,1949,408,994,365,349,1982,1447,1912
|
0.6491388771216718,0.14131998091565823,-0.14250621643165773,-0.011824157758994824,1.1194802025914279,1.3531319100008414,0.09070253409564899,3.6443989474477476,-0.11613860568977677,1.1194802025914279,0.14131998091565823,-0.14250621643165773,0.944268201707387,0.460522082895191,0.412471861925284,-0.16899212443771205,0.5555333123030265,0.16647131175699767,0.625866314583955,0.6491388771216718,-0.16899212443771205,0.013971984461395193,-0.14250621643165773
| 3,447
|
Apical plasma membrane
| 17
| 45
| 2.603813
| 0.009219
|
Q12959,P08195,O75955,Q9NV96,P51790,P11166,P30825,P19022,P41440,P36543,P08183,P05026,P54709,P33527,Q13131,Q16625,O14745
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
408,161,196,271,70,263,140,110,359,447,113,183,221,153,377,157,338
|
2075,338,3331,759,196,1616,1459,183,113,161,1706,905,263,1927,708,110,908,1543,1173,711,140,153,673,447,1467,1037,359,70,1942,221,491,1338,408,377,549,687,157,3164,1975,1303,955,271,751,2947,1912
|
-0.22232443406475605,0.6491388771216718,-1.057631062572967,0.26605328440668863,1.054317838750862,-0.06375283048767906,-0.011824157758994824,1.1194802025914279,1.9910092185928823,1.3531319100008414,-0.08988792448924106,0.19151921531853922,0.80972375426467,-0.16899212443771205,0.290698308478738,2.0100448717400776,0.19151921531853922,-0.037732006077157064,0.09070253409564899,0.290698308478738,1.5790322112008415,1.4154814144632912,0.3152452291356413,0.5082068465574456,-0.011824157758994824,0.14131998091565823,0.625866314583955,3.0545841549970008,-0.16899212443771205,0.944268201707387,0.460522082895191,0.03965766766041974,0.5555333123030265,0.6025084155120215,0.412471861925284,0.3152452291356413,1.3947613988096557,-0.7552547701634187,-0.16899212443771205,0.06523411656369492,0.19151921531853922,0.80972375426467,0.290698308478738,-0.5814925595785796,-0.14250621643165773
| 3,447
|
Action potential
| 10
| 21
| 2.59748
| 0.009391
|
Q12959,P54289,Q14126,P78310,P0DP25,P04062,Q06787,P62258,P05026,Q96PU5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
408,131,137,136,104,114,315,517,183,349
|
2079,114,1459,183,104,1928,1710,811,2393,1714,1468,131,517,136,545,315,1949,408,137,1492,349
|
-0.22232443406475605,1.952786157251336,-0.011824157758994824,1.1194802025914279,2.179150607376429,-0.16899212443771205,-0.08988792448924106,0.24130912809996094,-0.33047177855621607,-0.08988792448924106,-0.011824157758994824,1.6593829626856886,0.43654311105882554,1.6193233192302938,0.412471861925284,0.6954312126789955,-0.16899212443771205,0.5555333123030265,1.6193233192302938,-0.011824157758994824,0.6491388771216718
| 3,447
|
Trans golgi network
| 13
| 68
| 2.595818
| 0.009437
|
Q7Z6M1,P05067,Q7Z3C6,Q96A57,Q9UID3,Q15334,P20645,O43493,P98194,P04062,Q9C005,Q9NX62,P11717
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
33,66,132,234,307,206,142,18,298,114,320,94,31
|
1606,1763,702,18,1695,1917,2904,505,1840,857,114,66,357,31,142,2393,1171,3085,1113,1863,3044,481,3046,1336,2964,2475,819,1628,1730,2666,298,1121,2345,1047,2406,2486,206,454,1569,1054,688,132,33,1805,3100,1745,483,3134,234,1657,1140,1364,2739,795,2558,1589,1591,320,3328,1673,1595,94,2503,307,2243,2069,321,2249
|
-0.06375283048767906,-0.11613860568977677,0.290698308478738,4.925863408400397,-0.08988792448924106,-0.16899212443771205,-0.5814925595785796,0.43654311105882554,-0.14250621643165773,0.21646479318514736,1.952786157251336,3.185852181395418,0.625866314583955,4.393795198319631,1.5587987614920094,-0.33047177855621607,0.09070253409564899,-0.6967305875166148,0.11606410191198446,-0.14250621643165773,-0.6676978506562085,0.48440969406177936,-0.6676978506562085,0.03965766766041974,-0.6100808230827668,-0.3578263417200354,0.24130912809996094,-0.06375283048767906,-0.08988792448924106,-0.44067800799054646,0.7184525652536403,0.11606410191198446,-0.3032458564235702,0.14131998091565823,-0.33047177855621607,-0.3578263417200354,1.032454143437075,0.5082068465574456,-0.037732006077157064,0.14131998091565823,0.3152452291356413,1.6593829626856886,4.266269685759162,-0.11613860568977677,-0.6967305875166148,-0.08988792448924106,0.48440969406177936,-0.7259155280154393,0.899727495712953,-0.06375283048767906,0.11606410191198446,0.03965766766041974,-0.46856343097646624,0.26605328440668863,-0.38531114273962846,-0.037732006077157064,-0.037732006077157064,0.6954312126789955,-1.0266222601373636,-0.06375283048767906,-0.037732006077157064,2.416723651268817,-0.3578263417200354,0.7184525652536403,-0.2491737041569007,-0.19559772347892793,0.6954312126789955,-0.2491737041569007
| 3,447
|
Disproportionate short stature
| 8
| 25
| 2.57981
| 0.009885
|
P16278,Q15125,P10644,Q15392,Q7LGA3,Q9UBM7,Q14739,Q32P28
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,68,193,9,107,86,87,185
|
2997,1691,2389,2907,193,35,3004,1468,638,2765,3155,991,87,683,68,9,185,433,107,552,412,283,1811,86,891
|
-0.6388152651515875,-0.08988792448924106,-0.33047177855621607,-0.5814925595785796,1.0761096734158762,4.165756851456292,-0.6388152651515875,-0.011824157758994824,0.33969505804727207,-0.49658581124515616,-0.7552547701634187,0.16647131175699767,2.5415711073347276,0.3152452291356413,3.120491344892983,5.327333042658442,1.1194802025914279,0.5319144280730378,2.104478107048702,0.412471861925284,0.5555333123030265,0.764249500072063,-0.11613860568977677,2.5768641425022323,0.21646479318514736
| 3,447
|
Vascular transport
| 8
| 14
| 2.57822
| 0.009931
|
Q15758,P11166,P30825,P08183,P02786,P33527,Q07954,O14745
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
343,263,140,113,52,153,60,338
|
338,52,113,263,1173,140,153,359,1942,491,576,60,343,2417
|
0.6491388771216718,3.6443989474477476,1.9910092185928823,0.80972375426467,0.09070253409564899,1.5790322112008415,1.4154814144632912,0.625866314583955,-0.16899212443771205,0.460522082895191,0.3883074039088583,3.362871077444676,0.6491388771216718,-0.33047177855621607
| 3,447
|
Sterol transport
| 7
| 25
| 2.577605
| 0.009949
|
P01130,Q07954,Q6IAA8,O15118,P10909,P61916,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
73,60,238,57,58,28,62
|
57,1768,762,73,2462,58,1171,2581,3381,2958,28,60,238,256,3101,62,2784,1011,1979,3140,887,797,2375,1597,754
|
3.520478778498601,-0.11613860568977677,0.26605328440668863,3.0214219227005468,-0.3578263417200354,3.4892019402118737,0.09070253409564899,-0.41292781072703233,-1.3451913690083444,-0.6100808230827668,4.602257829733616,3.362871077444676,0.8773428842135269,0.8323417145063771,-0.6967305875166148,3.3469394788706537,-0.49658581124515616,0.16647131175699767,-0.16899212443771205,-0.7259155280154393,0.21646479318514736,0.26605328440668863,-0.3032458564235702,-0.037732006077157064,0.290698308478738
| 3,447
|
Cell surface interactions at the vascular wall
| 8
| 18
| 2.573144
| 0.010078
|
P35613,Q08722,P08195,P78310,Q9UNN8,P05026,Q9Y624,Q92896
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,194,161,136,85,183,121,63
|
183,507,1848,488,161,404,1244,160,1942,221,867,136,2670,194,3014,63,85,121
|
1.1194802025914279,0.43654311105882554,-0.14250621643165773,0.460522082895191,1.3531319100008414,0.5555333123030265,0.06523411656369492,1.3739783978655824,-0.16899212443771205,0.944268201707387,0.21646479318514736,1.6193233192302938,-0.44067800799054646,1.0761096734158762,-0.6388152651515875,3.3469394788706537,2.594448993407223,1.8368772029414835
| 3,447
|
Cell Junctions
| 16
| 60
| 2.570466
| 0.010156
|
Q9Y624,Q9UGI8,Q14574,Q5KU26,Q14126,P78310,Q86UT6,Q99519,Q9UJA5,P19022,Q9BY67,P29317,Q16625,P53602,P33527,O43657
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
121,295,69,38,137,136,366,75,244,110,175,178,157,279,153,29
|
755,2569,1915,2328,29,2386,3076,569,2159,1928,1710,110,178,153,1546,980,915,1548,3088,279,1942,1183,136,2103,1734,2483,137,1279,69,2352,157,2727,38,364,1351,3253,2680,2779,366,618,3100,1065,587,75,2368,838,175,885,3351,2062,3386,590,295,244,3352,1086,2072,630,895,121
|
0.26605328440668863,-0.41292781072703233,-0.16899212443771205,-0.3032458564235702,4.5333220168762525,-0.33047177855621607,-0.6967305875166148,0.3883074039088583,-0.2491737041569007,-0.16899212443771205,-0.08988792448924106,2.0100448717400776,1.162570531532433,1.4154814144632912,-0.037732006077157064,0.16647131175699767,0.19151921531853922,-0.037732006077157064,-0.6967305875166148,0.764249500072063,-0.16899212443771205,0.09070253409564899,1.6193233192302938,-0.22232443406475605,-0.08988792448924106,-0.3578263417200354,1.6193233192302938,0.06523411656369492,3.1040662322378125,-0.3032458564235702,1.3947613988096557,-0.46856343097646624,4.136820106166587,0.625866314583955,0.03965766766041974,-0.8741983970490654,-0.44067800799054646,-0.49658581124515616,0.625866314583955,0.36404879012622693,-0.6967305875166148,0.14131998091565823,0.3883074039088583,3.0047879739765255,-0.3032458564235702,0.24130912809996094,1.1840120855874656,0.21646479318514736,-1.1201939880656602,-0.19559772347892793,-1.3451913690083444,0.3883074039088583,0.7413917409113739,0.8773428842135269,-1.1201939880656602,0.14131998091565823,-0.19559772347892793,0.36404879012622693,0.21646479318514736,1.8368772029414835
| 3,447
|
Regulation of nervous system development
| 18
| 70
| 2.562626
| 0.010388
|
Q12959,P07196,Q9UIW2,O14786,Q9UQB8,Q13641,Q96G23,P01130,Q9UBS4,Q14444,P26583,P53634,O94813,P55209,Q15375,Q15058,P21359,Q7L576
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
408,310,225,99,97,37,168,73,243,392,297,20,84,118,119,379,220,223
|
803,99,804,2384,2257,968,1770,84,1612,73,2333,310,488,1617,220,297,978,3381,512,1546,1937,1468,816,2177,20,118,1867,1188,2103,2346,545,1562,408,1123,3089,926,1478,37,392,379,1347,119,3302,430,877,223,2835,1963,2687,168,1433,2045,3320,1755,2432,1821,2063,2943,1146,243,3389,225,2146,1019,2069,2323,1086,798,97,2947
|
0.24130912809996094,2.308023112336245,0.24130912809996094,-0.33047177855621607,-0.2761470099076228,0.16647131175699767,-0.11613860568977677,2.6294966021683392,-0.06375283048767906,3.0214219227005468,-0.3032458564235702,0.6954312126789955,0.460522082895191,-0.06375283048767906,0.944268201707387,0.7184525652536403,0.16647131175699767,-1.3451913690083444,0.43654311105882554,-0.037732006077157064,-0.16899212443771205,-0.011824157758994824,0.24130912809996094,-0.2491737041569007,4.872739253374519,1.8757230653380457,-0.14250621643165773,0.09070253409564899,-0.22232443406475605,-0.3032458564235702,0.412471861925284,-0.037732006077157064,0.5555333123030265,0.11606410191198446,-0.6967305875166148,0.19151921531853922,-0.011824157758994824,4.136820106166587,0.5790643592485345,0.6025084155120215,0.03965766766041974,1.8757230653380457,-0.9651364301489054,0.5319144280730378,0.21646479318514736,0.944268201707387,-0.5247469164830378,-0.16899212443771205,-0.44067800799054646,1.2902064105323907,0.013971984461395193,-0.19559772347892793,-0.9957915972367293,-0.08988792448924106,-0.33047177855621607,-0.11613860568977677,-0.19559772347892793,-0.5814925595785796,0.11606410191198446,0.8773428842135269,-1.3781294605421666,0.944268201707387,-0.22232443406475605,0.16647131175699767,-0.19559772347892793,-0.2761470099076228,0.14131998091565823,0.26605328440668863,2.3444338300023935,-0.5814925595785796
| 3,447
|
Regulation of proteasomal ubiquitin dependent protein catabolic process
| 11
| 56
| 3.421374
| 0.000623
|
Q9BTA9,Q8NEZ5,Q9BW61,O43765,Q9NZL4,Q9UBS8,Q9H000,O00560,Q8IXJ6,P78559,O15372
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,261,100,7,178,73,17,146,50,245,158
|
146,1343,1479,1728,158,7,415,1956,889,3333,1603,2155,2160,601,1686,1427,2912,973,731,2984,977,1748,1617,1751,838,1908,1301,245,902,1916,2612,50,2257,261,1707,283,1194,620,752,2828,1,100,1201,17,2528,178,2269,73,1533,2137,560,632,2139,411,1074,1537
|
1.1729039116516042,0.14055920679442668,0.08846302330909535,-0.01588339248816641,1.1216796679268493,5.471572567824065,0.6588880680272334,-0.09428154235373645,0.3484500400782194,-1.5817900434130296,0.03631578405272416,-0.17280182112563378,-0.17280182112563378,0.5038712950051047,0.010222744193719364,0.1145174430622166,-0.5673604973578883,0.2965498167601974,0.4262123823488152,-0.6202311111444645,0.2965498167601974,-0.01588339248816641,0.03631578405272416,-0.01588339248816641,0.37438246142501497,-0.06813541787919085,0.16658842023685425,0.9420920779153221,0.3484500400782194,-0.06813541787919085,-0.35651011446187664,1.9370073166859738,-0.19900296686591165,0.9163974154088532,0.010222744193719364,0.8649779587240712,0.21860961070595744,0.5038712950051047,0.4262123823488152,-0.4881748174530137,12.741750894706325,1.402955118769559,0.21860961070595744,3.2451792675084628,-0.3039496266010951,1.0960533169755888,-0.19900296686591165,1.6577255052032591,0.08846302330909535,-0.14661461977842807,0.5555875994245117,0.5038712950051047,-0.14661461977842807,0.6846861232304023,0.2705818269915089,0.08846302330909535
| 3,437
|
Fc epsilon receptor fceri signaling
| 25
| 53
| 3.281559
| 0.001032
|
P28070,Q99436,Q16512,P49721,O15111,P55036,P61088,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P62993,P19174,P27361,P28482,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,657,19,27,645,647,649,36,287,44,528,416,415,677,183,63,687,205,99,477,602,482,364,368
|
528,2480,1339,1278,677,1342,27,1668,883,1410,415,831,205,63,2162,1085,416,1357,99,1088,10,44,287,477,1611,2237,2101,183,19,2789,645,602,647,1095,364,649,482,687,2499,935,1758,3236,1990,2604,2752,36,368,1173,657,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.16658842023685425,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.3484500400782194,0.1145174430622166,0.6588880680272334,0.37438246142501497,1.0191166070744402,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,1.402955118769559,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.6072596412110887,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.4779963367555763,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.4521100613445833,-0.3039496266010951,0.3225058562487884,-0.01588339248816641,-1.0720860968906154,-0.09428154235373645,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.21860961070595744,0.4779963367555763,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Tcr signaling
| 24
| 49
| 3.134579
| 0.001721
|
P28070,Q99436,Q16512,P49721,O15111,P55036,P61088,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,Q8N8S7,O00487,P49720,P20618,P19174,P60900,P50552,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,657,19,27,645,647,649,36,287,44,528,416,415,583,677,183,63,205,602,235,482,364,368
|
528,2480,1339,1278,677,1342,27,1668,883,415,831,205,63,2162,1085,416,1357,1088,10,44,287,1611,1972,2237,2101,183,19,235,2789,645,602,647,1095,364,649,482,935,1758,1990,2604,2752,36,368,657,583,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.16658842023685425,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.3484500400782194,0.6588880680272334,0.37438246142501497,1.0191166070744402,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.09428154235373645,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,0.9677767865553218,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.4779963367555763,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.09428154235373645,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.4779963367555763,0.5297350212533344,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Orc1 removal from chromatin
| 24
| 52
| 3.101132
| 0.001928
|
P28070,Q99436,P49721,P33991,P55036,P62195,Q14997,P28074,P28072,Q9UBD5,O00231,P25788,O75832,O00487,P49720,P20618,Q13416,Q9UL46,P60900,P33993,P62333,Q13309,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,641,645,649,36,287,44,315,528,416,415,677,183,63,207,759,602,233,482,604,364,368
|
528,2480,1339,677,1342,1668,415,831,3010,63,2160,724,2162,1085,416,1357,1088,10,44,287,641,971,233,1611,2237,2101,183,19,933,2789,645,602,1095,364,649,482,935,1758,2604,604,207,2752,1562,36,368,275,1124,315,2210,759,1793,2215
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,-0.6466903057401047,1.759396490717528,-0.17280182112563378,0.4262123823488152,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.4779963367555763,0.2965498167601974,0.9677767865553218,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,0.3225058562487884,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.35651011446187664,0.5038712950051047,1.0191166070744402,-0.4354630136619837,0.062395840059970745,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.8135178673565373,-0.17280182112563378,0.4262123823488152,-0.01588339248816641,-0.17280182112563378
| 3,437
|
Regulation of ubiquitin dependent protein catabolic process
| 12
| 66
| 2.960393
| 0.003072
|
Q9BTA9,Q8NEZ5,Q9BW61,O43765,Q9NZL4,Q9UBS8,Q05397,Q9H000,O00560,Q8IXJ6,P78559,O15372
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,261,100,7,178,73,269,17,146,50,245,158
|
146,1343,1479,1728,158,7,926,415,1956,889,3333,1603,2155,1813,2160,601,1686,1974,1427,2912,973,731,2984,977,1748,1617,1751,838,2368,2105,1908,1301,2302,245,902,1621,269,1916,2612,50,2257,261,1707,283,1194,620,2710,752,2828,1,100,1201,17,409,2528,178,2269,73,1533,2137,560,632,2139,411,1074,1537
|
1.1729039116516042,0.14055920679442668,0.08846302330909535,-0.01588339248816641,1.1216796679268493,5.471572567824065,0.3225058562487884,0.6588880680272334,-0.09428154235373645,0.3484500400782194,-1.5817900434130296,0.03631578405272416,-0.17280182112563378,-0.042002740889055014,-0.17280182112563378,0.5038712950051047,0.010222744193719364,-0.09428154235373645,0.1145174430622166,-0.5673604973578883,0.2965498167601974,0.4262123823488152,-0.6202311111444645,0.2965498167601974,-0.01588339248816641,0.03631578405272416,-0.01588339248816641,0.37438246142501497,-0.25144761327768334,-0.14661461977842807,-0.06813541787919085,0.16658842023685425,-0.22521818684495445,0.9420920779153221,0.3484500400782194,0.03631578405272416,0.890692731740149,-0.06813541787919085,-0.35651011446187664,1.9370073166859738,-0.19900296686591165,0.9163974154088532,0.010222744193719364,0.8649779587240712,0.21860961070595744,0.5038712950051047,-0.40913022679566735,0.4262123823488152,-0.4881748174530137,12.741750894706325,1.402955118769559,0.21860961070595744,3.2451792675084628,0.6846861232304023,-0.3039496266010951,1.0960533169755888,-0.19900296686591165,1.6577255052032591,0.08846302330909535,-0.14661461977842807,0.5555875994245117,0.5038712950051047,-0.14661461977842807,0.6846861232304023,0.2705818269915089,0.08846302330909535
| 3,437
|
Pcp ce pathway
| 24
| 52
| 2.888726
| 0.003868
|
P28070,Q99436,P49721,O14641,P55036,P07737,P62195,Q14997,P28074,P28072,P63010,O00231,P25788,O75832,O00487,P49720,P20618,Q00610,O94973,Q9UL46,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,762,645,30,649,36,287,44,779,528,416,415,677,183,63,688,825,759,602,482,364,368
|
528,2480,1339,677,762,1342,1668,415,825,1808,30,1810,2846,3050,831,63,2162,1085,416,1357,1088,10,44,287,1150,1611,2237,2101,183,19,2789,1158,645,602,1095,1754,364,649,482,2499,779,688,1758,2604,2856,36,368,1118,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.4003032120537953,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,-0.042002740889055014,2.467578902400475,-0.042002740889055014,-0.5145541510399857,-0.6996557465222012,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.21860961070595744,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.21860961070595744,0.4779963367555763,0.5038712950051047,0.24460179084386904,-0.01588339248816641,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.3039496266010951,0.4003032120537953,0.4521100613445833,-0.01588339248816641,-0.35651011446187664,-0.5145541510399857,2.341547868171487,0.7104735093783054,0.24460179084386904,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
The role of gtse1 in g2 m progression after g2 checkpoint
| 22
| 48
| 2.880269
| 0.003973
|
P28070,Q99436,Q15691,P49721,P55036,P62195,Q9BUF5,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9BVA1,P60900,P04350,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,399,19,645,649,437,36,287,44,528,416,415,677,183,63,357,602,475,482,364,368
|
528,2480,1339,677,1342,1668,415,475,2540,927,1349,1603,893,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,977,645,602,1095,364,649,482,1097,1758,2604,36,368,399,275,1124,437,357,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.6072596412110887,-0.3302224903627467,0.3225058562487884,0.14055920679442668,0.03631578405272416,0.3484500400782194,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.2965498167601974,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.24460179084386904,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.6846861232304023,0.890692731740149,0.24460179084386904,0.6588880680272334,0.736250302444436,0.4262123823488152,-0.01588339248816641
| 3,437
|
Regulation of actin cytoskeleton
| 32
| 56
| 2.876984
| 0.004015
|
P35579,Q9Y6W5,P46108,P62136,Q9UQB8,Q13464,Q05397,Q16512,O43707,P05556,P35580,P12814,P46940,O60610,P07737,O60879,Q14155,Q8N8S7,P15311,Q92747,O15144,Q7L576,O14974,P62140,Q9UBI6,P26038,P27361,P35241,P28482,P06756,P59998,Q7Z406
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
505,923,258,900,13,510,269,657,635,891,897,393,395,765,30,285,543,583,683,461,566,326,318,737,496,832,99,352,477,718,480,374
|
1278,318,566,2085,635,765,285,1013,891,718,30,393,683,1146,969,1148,2161,832,99,477,352,505,897,2098,1972,258,2363,395,480,2169,1754,3160,900,737,2499,1502,269,1990,510,1766,543,2250,657,326,374,1183,583,1456,461,956,496,2211,13,2804,1273,923
|
0.16658842023685425,0.78777240802752,0.5297350212533344,-0.14661461977842807,0.4779963367555763,0.4003032120537953,0.8392530272685477,0.2705818269915089,0.3484500400782194,0.4262123823488152,2.467578902400475,0.6846861232304023,0.4521100613445833,0.21860961070595744,0.2965498167601974,0.21860961070595744,-0.17280182112563378,0.37438246142501497,1.402955118769559,0.6072596412110887,0.736250302444436,0.5814291122334218,0.3484500400782194,-0.14661461977842807,-0.09428154235373645,0.9163974154088532,-0.25144761327768334,0.6846861232304023,0.6072596412110887,-0.17280182112563378,-0.01588339248816641,-0.8589185757995703,0.3484500400782194,0.4262123823488152,-0.3039496266010951,0.08846302330909535,0.890692731740149,-0.09428154235373645,0.5814291122334218,-0.01588339248816641,0.5555875994245117,-0.19900296686591165,0.4779963367555763,0.78777240802752,0.7104735093783054,0.21860961070595744,0.5297350212533344,0.1145174430622166,0.6330792667297674,0.3225058562487884,0.6072596412110887,-0.17280182112563378,4.239890873327849,-0.4618111582937517,0.19260518741836744,0.3484500400782194
| 3,437
|
Endopeptidase complex
| 21
| 54
| 2.872042
| 0.004078
|
P28070,Q99436,O43396,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9UL46,Q9UMX0,P60900,P62333,P62191,Q15008
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
10,275,14,19,645,649,36,287,44,528,416,415,677,183,63,759,632,602,482,364,368
|
528,2480,1339,677,1342,1668,14,1141,415,3336,1147,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,1748,1617,645,1751,602,1095,364,649,482,1621,1758,2604,36,368,1172,2859,795,3022,1257,1520,275,1124,1205,759,632,1793,1537
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,3.8679292480336267,0.21860961070595744,0.6588880680272334,-1.6357045003570223,0.21860961070595744,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,-0.01588339248816641,0.03631578405272416,0.4779963367555763,-0.01588339248816641,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.03631578405272416,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.21860961070595744,-0.5145541510399857,0.4003032120537953,-0.6466903057401047,0.19260518741836744,0.08846302330909535,0.890692731740149,0.24460179084386904,0.21860961070595744,0.4262123823488152,0.5038712950051047,-0.01588339248816641,0.08846302330909535
| 3,437
|
Hedgehog off state
| 23
| 52
| 2.866786
| 0.004147
|
P28070,Q99436,P49721,Q96J02,P55036,P62195,Q9BUF5,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9UL46,Q9BVA1,P60900,P04350,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,157,645,649,437,36,287,44,528,416,415,677,183,63,759,357,602,475,482,364,368
|
528,2480,1339,677,1342,1668,415,475,829,1890,3050,2786,831,63,2162,1085,416,1357,1088,10,44,287,1968,1611,2237,2101,2912,183,19,731,2789,645,602,1095,364,649,482,935,1097,1758,2604,2752,36,368,2708,157,275,1124,437,357,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.6072596412110887,0.37438246142501497,-0.06813541787919085,-0.6996557465222012,-0.4618111582937517,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,-0.09428154235373645,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,-0.5673604973578883,1.070417398184814,3.09516261931888,0.4262123823488152,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,0.24460179084386904,-0.01588339248816641,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,-0.40913022679566735,1.1472965125647505,0.890692731740149,0.24460179084386904,0.6588880680272334,0.736250302444436,0.4262123823488152,-0.01588339248816641
| 3,437
|
C type lectin receptors clrs
| 21
| 53
| 2.831973
| 0.004626
|
P28070,Q99436,Q16512,P49721,O15111,P55036,P61088,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,657,19,27,645,647,649,36,287,44,528,416,415,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,27,1668,883,1410,415,1676,3050,2786,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1094,647,1095,364,649,482,935,1987,1758,3236,1990,2604,2752,36,368,1173,657,2922,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.3484500400782194,0.1145174430622166,0.6588880680272334,0.010222744193719364,-0.6996557465222012,-0.4618111582937517,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.4779963367555763,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.09428154235373645,-0.01588339248816641,-1.0720860968906154,-0.09428154235373645,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.21860961070595744,0.4779963367555763,-0.5673604973578883,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Interleukin 1 family signaling
| 21
| 49
| 2.828017
| 0.004684
|
P28070,Q99436,P49721,O15111,P55036,P61088,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9UL46,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,27,645,647,649,36,287,44,528,416,415,677,183,63,759,602,482,364,368
|
528,2480,1339,677,1342,27,1668,883,415,2845,720,831,63,2162,1085,416,1357,1088,10,44,287,1611,2689,2237,2101,183,19,2789,645,602,647,1095,364,649,482,935,1502,1914,1758,2604,1627,2752,36,368,1173,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.3484500400782194,0.6588880680272334,-0.5145541510399857,0.4262123823488152,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.40913022679566735,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.4779963367555763,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,0.08846302330909535,-0.06813541787919085,-0.01588339248816641,-0.35651011446187664,0.03631578405272416,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.21860961070595744,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Degradation of beta catenin by the destruction complex
| 23
| 49
| 2.809897
| 0.004956
|
P28070,Q99436,Q13547,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q14738,Q9UL46,P60900,P30154,P62333,P62191,Q13363,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,511,19,645,649,36,287,44,528,416,415,677,183,63,692,759,602,232,482,364,124,368
|
528,2480,1339,677,1342,1668,415,831,63,2161,2162,1085,416,1357,1088,10,44,287,1683,232,1819,1611,2237,2101,2912,183,19,731,2789,645,3206,602,1095,364,649,482,935,1758,2604,124,511,2752,692,36,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.010222744193719364,0.9677767865553218,-0.042002740889055014,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,-0.5673604973578883,1.070417398184814,3.09516261931888,0.4262123823488152,-0.4618111582937517,0.4779963367555763,-0.9653888365499469,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.35651011446187664,1.2496700320630116,0.5814291122334218,-0.4354630136619837,0.4521100613445833,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Interleukin 1 signaling
| 21
| 47
| 2.752311
| 0.005918
|
P28070,Q99436,P49721,O15111,P55036,P61088,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9UL46,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,27,645,647,649,36,287,44,528,416,415,677,183,63,759,602,482,364,368
|
528,2480,1339,677,1342,27,1668,883,415,2845,720,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,647,1095,364,649,482,935,1502,1758,2604,1627,2752,36,368,1173,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.3484500400782194,0.6588880680272334,-0.5145541510399857,0.4262123823488152,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.4779963367555763,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,0.08846302330909535,-0.01588339248816641,-0.35651011446187664,0.03631578405272416,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.21860961070595744,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
| 21
| 50
| 2.728989
| 0.006353
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q16763,P60900,Q96DE5,P62333,Q13309,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,677,183,63,740,602,376,482,604,364,368
|
528,2480,1339,677,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,2688,1611,2237,2101,183,19,2789,977,645,602,1095,364,649,482,1758,2053,2604,604,36,368,740,376,2800,275,1124,1526,869,1335,2081,3200,2211,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,-0.40913022679566735,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.2965498167601974,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.12044123528532528,-0.35651011446187664,0.5038712950051047,2.341547868171487,0.7104735093783054,0.4262123823488152,0.7104735093783054,-0.4618111582937517,0.890692731740149,0.24460179084386904,0.08846302330909535,0.37438246142501497,0.16658842023685425,-0.12044123528532528,-0.9387496993351647,-0.17280182112563378,0.4262123823488152,-0.01588339248816641
| 3,437
|
Proteasome complex
| 21
| 48
| 2.723129
| 0.006467
|
P28070,Q99436,O43396,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9UL46,Q9UMX0,P60900,P62333,P62191,Q15008
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
10,275,14,19,645,649,36,287,44,528,416,415,677,183,63,759,632,602,482,364,368
|
528,2480,1339,677,1342,1668,14,415,3336,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,1748,1617,645,1751,602,1095,364,649,482,1621,1758,2604,36,368,1172,2859,795,275,1124,759,632,1793,1537
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,3.8679292480336267,0.6588880680272334,-1.6357045003570223,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,-0.01588339248816641,0.03631578405272416,0.4779963367555763,-0.01588339248816641,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.03631578405272416,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.21860961070595744,-0.5145541510399857,0.4003032120537953,0.890692731740149,0.24460179084386904,0.4262123823488152,0.5038712950051047,-0.01588339248816641,0.08846302330909535
| 3,437
|
Single transverse palmar crease
| 6
| 48
| 2.72006
| 0.006527
|
Q9BTA9,P56589,P51812,Q96J02,Q13363,Q9Y263
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,122,57,157,124,29
|
2726,883,1219,1283,3192,2090,1958,2153,2027,1680,2161,1492,835,1899,1821,1025,57,122,1026,2369,222,782,124,1993,3170,2183,987,1697,1841,3097,1842,1512,3196,1575,2998,157,1520,1649,1,2327,2463,2132,3223,1473,1070,29,2143,2018
|
-0.4354630136619837,0.3484500400782194,0.19260518741836744,0.16658842023685425,-0.9387496993351647,-0.14661461977842807,-0.09428154235373645,-0.17280182112563378,-0.12044123528532528,0.010222744193719364,-0.17280182112563378,0.08846302330909535,0.37438246142501497,-0.06813541787919085,-0.042002740889055014,0.2705818269915089,1.8101826910064611,1.2496700320630116,0.2705818269915089,-0.25144761327768334,0.9934516077523754,0.4003032120537953,1.2496700320630116,-0.09428154235373645,-0.8855144491446009,-0.17280182112563378,0.2965498167601974,0.010222744193719364,-0.042002740889055014,-0.7526829888195903,-0.042002740889055014,0.08846302330909535,-0.9387496993351647,0.062395840059970745,-0.6202311111444645,1.1472965125647505,0.08846302330909535,0.03631578405272416,12.741750894706325,-0.22521818684495445,-0.27769138081303274,-0.14661461977842807,-0.9920421587976711,0.1145174430622166,0.2705818269915089,2.54311235991026,-0.14661461977842807,-0.09428154235373645
| 3,437
|
Antigen processing cross presentation
| 24
| 55
| 2.692652
| 0.007089
|
P28070,Q99436,P49721,P01889,O15111,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9UL46,P60900,P06756,P09429,P62333,P62191,Q03518,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,148,27,645,649,36,287,44,528,416,415,677,183,63,759,602,718,720,482,364,246,368
|
1724,528,2480,1339,677,1342,27,1668,2346,415,148,3089,718,720,721,831,63,2162,1085,416,1357,3072,1088,10,44,287,2550,1422,1611,2237,2101,183,19,2789,645,1980,602,1095,2695,364,649,482,246,3369,1758,783,2604,36,368,275,1124,2835,2209,759,1793
|
-0.01588339248816641,0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,-0.25144761327768334,0.6588880680272334,1.1729039116516042,-0.7526829888195903,0.4262123823488152,0.4262123823488152,0.4262123823488152,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,-0.7261617112368798,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,-0.3302224903627467,0.1145174430622166,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,-0.09428154235373645,0.5038712950051047,0.24460179084386904,-0.40913022679566735,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.9420920779153221,-2.014392751468817,-0.01588339248816641,0.4003032120537953,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,-0.4881748174530137,-0.17280182112563378,0.4262123823488152,-0.01588339248816641
| 3,437
|
Regulation of pten stability and activity
| 19
| 44
| 2.673084
| 0.007516
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P31751,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,677,183,63,323,602,482,364,368
|
528,2480,1339,677,1342,1668,415,1738,831,1813,63,2162,1085,416,1357,1088,10,44,287,323,1611,2237,2435,2101,183,19,2789,645,602,1095,364,649,482,1373,2302,1758,2604,36,368,275,1124,759,2139,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,-0.01588339248816641,0.37438246142501497,-0.042002740889055014,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.78777240802752,0.03631578405272416,-0.19900296686591165,-0.27769138081303274,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.14055920679442668,-0.22521818684495445,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.14661461977842807,-0.01588339248816641
| 3,437
|
Clec7a dectin 1 signaling
| 20
| 49
| 2.661271
| 0.007785
|
P28070,Q99436,P49721,O15111,P55036,P61088,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,27,645,647,649,36,287,44,528,416,415,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,27,1668,883,1410,415,1676,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1094,647,1095,364,649,482,935,1987,1758,3236,2604,2752,36,368,1173,2922,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.3484500400782194,0.1145174430622166,0.6588880680272334,0.010222744193719364,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.4779963367555763,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.09428154235373645,-0.01588339248816641,-1.0720860968906154,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.21860961070595744,-0.5673604973578883,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Cdt1 association with the cdc6 orc origin complex
| 20
| 41
| 2.617041
| 0.00887
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,Q9UBD5,O00231,P25788,O75832,O00487,P49720,P20618,Q13416,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,315,528,416,415,677,183,63,207,602,482,364,368
|
528,2480,1339,677,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,207,36,368,275,1124,315,2210,759,1793,2215
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,1.0191166070744402,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.8135178673565373,-0.17280182112563378,0.4262123823488152,-0.01588339248816641,-0.17280182112563378
| 3,437
|
Threonine type peptidase activity
| 6
| 9
| 2.61228
| 0.008994
|
P20618,P28070,Q99436,P28072,P49721,P49720
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
63,10,275,44,19,183
|
63,1357,10,44,287,183,19,2796,275
|
1.759396490717528,0.14055920679442668,4.857234201516885,2.0636350154112697,0.8392530272685477,1.070417398184814,3.09516261931888,-0.4618111582937517,0.890692731740149
| 3,437
|
Dna replication pre initiation
| 28
| 65
| 2.612083
| 0.008999
|
Q14974,P28070,Q99436,P49721,P33991,P55036,P62195,Q14997,P28074,P28072,Q9UBD5,O00231,P25788,P35244,O75832,O00487,Q14181,P49720,P20618,O60684,Q13416,Q9UL46,P60900,P33993,P62333,P25205,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
656,10,275,19,641,645,649,36,287,44,315,528,416,417,415,677,56,183,63,568,207,759,602,233,482,724,364,368
|
528,2480,1339,677,1342,1668,568,415,1887,2230,3205,831,63,2160,724,2162,1085,416,1357,1022,1088,10,44,287,641,971,233,417,1611,2237,2101,1494,2103,183,19,933,2789,732,645,602,1095,364,649,482,3181,2992,1758,1164,2604,207,56,1562,656,36,368,1179,275,1124,1331,1943,315,2210,759,1793,2215
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.5297350212533344,0.6588880680272334,-0.06813541787919085,-0.19900296686591165,-0.9653888365499469,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.4262123823488152,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.2705818269915089,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.4779963367555763,0.2965498167601974,0.9677767865553218,0.6588880680272334,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,0.08846302330909535,-0.14661461977842807,1.070417398184814,3.09516261931888,0.3225058562487884,-0.4618111582937517,0.4262123823488152,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.912124863937556,-0.6202311111444645,-0.01588339248816641,0.21860961070595744,-0.35651011446187664,1.0191166070744402,1.8355636276165608,0.062395840059970745,0.4779963367555763,2.341547868171487,0.7104735093783054,0.21860961070595744,0.890692731740149,0.24460179084386904,0.16658842023685425,-0.06813541787919085,0.8135178673565373,-0.17280182112563378,0.4262123823488152,-0.01588339248816641,-0.17280182112563378
| 3,437
|
Negative regulation of protein catabolic process
| 6
| 46
| 2.609818
| 0.009059
|
Q9BTA9,Q9NQ11,O43765,O00560,Q8IXJ6,O15372
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,242,7,146,50,158
|
146,1343,1728,158,7,2021,1485,2421,3114,1603,2785,3390,1813,1680,2595,1686,1974,973,1748,1027,2368,2105,1908,2302,245,902,1691,510,2505,2756,2612,50,2257,1707,1194,620,2710,752,1585,2828,1,409,242,2269,2137,1537
|
1.1729039116516042,0.14055920679442668,-0.01588339248816641,1.1216796679268493,5.471572567824065,-0.12044123528532528,0.08846302330909535,-0.27769138081303274,-0.7792194448781685,0.03631578405272416,-0.4618111582937517,-2.3134268978871475,-0.042002740889055014,0.010222744193719364,-0.35651011446187664,0.010222744193719364,-0.09428154235373645,0.2965498167601974,-0.01588339248816641,0.2705818269915089,-0.25144761327768334,-0.14661461977842807,-0.06813541787919085,-0.22521818684495445,0.9420920779153221,0.3484500400782194,0.010222744193719364,0.5814291122334218,-0.3039496266010951,-0.4354630136619837,-0.35651011446187664,1.9370073166859738,-0.19900296686591165,0.010222744193719364,0.21860961070595744,0.5038712950051047,-0.40913022679566735,0.4262123823488152,0.062395840059970745,-0.4881748174530137,12.741750894706325,0.6846861232304023,0.9677767865553218,-0.19900296686591165,-0.14661461977842807,0.08846302330909535
| 3,437
|
Threonine type endopeptidase activity
| 6
| 8
| 2.605301
| 0.009179
|
P20618,P28070,Q99436,P28072,P49721,P49720
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
63,10,275,44,19,183
|
63,1357,10,44,287,183,19,275
|
1.759396490717528,0.14055920679442668,4.857234201516885,2.0636350154112697,0.8392530272685477,1.070417398184814,3.09516261931888,0.890692731740149
| 3,437
|
Proteasome beta-type subunit, conserved site [IPR016050]
| 6
| 8
| 2.605301
| 0.009179
|
P20618,P28070,Q99436,P28072,P49721,P49720
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
63,10,275,44,19,183
|
63,1357,10,44,287,183,19,275
|
1.759396490717528,0.14055920679442668,4.857234201516885,2.0636350154112697,0.8392530272685477,1.070417398184814,3.09516261931888,0.890692731740149
| 3,437
|
Switching of origins to a post replicative state
| 26
| 62
| 2.600764
| 0.009302
|
P28070,Q99436,P49721,P33991,P55036,P62195,Q14997,P28074,P28072,Q9UBD5,O00231,P25788,O75832,O00487,P49720,P20618,Q16763,Q13416,Q9UL46,P60900,Q96DE5,P33993,P62333,Q13309,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,641,645,649,36,287,44,315,528,416,415,677,183,63,740,207,759,602,376,233,482,604,364,368
|
528,2480,1339,677,1342,1668,415,831,3010,63,2160,724,2162,1085,416,1357,1088,10,44,287,2688,641,971,233,1611,2237,2101,183,19,933,2789,645,602,1095,364,649,482,935,1758,2053,2604,604,207,2752,1562,36,368,740,376,275,1124,1526,315,2210,869,1335,2081,3200,2211,759,1793,2215
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,-0.6466903057401047,1.759396490717528,-0.17280182112563378,0.4262123823488152,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,-0.40913022679566735,0.4779963367555763,0.2965498167601974,0.9677767865553218,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,0.3225058562487884,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.12044123528532528,-0.35651011446187664,0.5038712950051047,1.0191166070744402,-0.4354630136619837,0.062395840059970745,2.341547868171487,0.7104735093783054,0.4262123823488152,0.7104735093783054,0.890692731740149,0.24460179084386904,0.08846302330909535,0.8135178673565373,-0.17280182112563378,0.37438246142501497,0.16658842023685425,-0.12044123528532528,-0.9387496993351647,-0.17280182112563378,0.4262123823488152,-0.01588339248816641,-0.17280182112563378
| 3,437
|
Fceri mediated nf kb activation
| 20
| 43
| 2.598415
| 0.009366
|
P28070,Q99436,P49721,O15111,P55036,P61088,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,27,645,647,649,36,287,44,528,416,415,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,27,1668,883,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,647,1095,364,649,482,935,1758,2604,2752,36,368,1173,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.3484500400782194,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.4779963367555763,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.21860961070595744,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Uch proteinases
| 20
| 48
| 2.580532
| 0.009865
|
Q9Y4E8,P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,Q9H981,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
676,10,275,19,645,649,36,287,44,704,528,416,415,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,1728,1668,415,2810,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,1614,2789,645,602,1095,364,649,482,1758,2604,36,368,2859,3134,2763,275,1124,1651,704,759,1793,2779,676,1537
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,-0.01588339248816641,0.010222744193719364,0.6588880680272334,-0.4881748174530137,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,0.03631578405272416,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,-0.5145541510399857,-0.8057709474338041,-0.4354630136619837,0.890692731740149,0.24460179084386904,0.03631578405272416,0.4521100613445833,0.4262123823488152,-0.01588339248816641,-0.4354630136619837,0.4779963367555763,0.08846302330909535
| 3,437
|
Metabolism of polyamines
| 20
| 39
| 2.579475
| 0.009895
|
P28070,Q99436,P49721,P19623,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q6QHF9,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,394,645,649,36,287,44,528,416,415,677,183,63,87,602,482,364,368
|
528,2480,1339,677,1342,1668,415,831,394,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,36,368,87,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,0.6846861232304023,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,1.5304480389319417,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Beta catenin independent wnt signaling
| 27
| 58
| 2.558848
| 0.010502
|
P28070,Q99436,P49721,O14641,P55036,P07737,P62195,Q14997,P28074,P28072,P63010,O00231,P25788,O75832,O00487,P49720,P20618,Q00610,O94973,Q9UL46,P17980,Q9UBI6,P60900,P63218,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,762,645,30,649,36,287,44,779,528,416,415,677,183,63,688,825,759,831,496,602,840,482,364,368
|
528,2480,1339,677,762,1342,1668,883,415,825,1808,30,1810,2846,3050,831,63,2162,1085,416,1357,1088,10,44,287,1150,1819,1611,2237,2101,183,19,2789,1158,645,602,1095,1754,364,649,482,2499,779,840,688,1758,3236,2604,2856,36,368,1118,275,1124,2403,496,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.4003032120537953,0.14055920679442668,0.010222744193719364,0.3484500400782194,0.6588880680272334,0.37438246142501497,-0.042002740889055014,2.467578902400475,-0.042002740889055014,-0.5145541510399857,-0.6996557465222012,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.21860961070595744,-0.042002740889055014,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.21860961070595744,0.4779963367555763,0.5038712950051047,0.24460179084386904,-0.01588339248816641,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.3039496266010951,0.4003032120537953,0.37438246142501497,0.4521100613445833,-0.01588339248816641,-1.0720860968906154,-0.35651011446187664,-0.5145541510399857,2.341547868171487,0.7104735093783054,0.24460179084386904,0.890692731740149,0.24460179084386904,-0.25144761327768334,0.6072596412110887,0.4262123823488152,-0.01588339248816641
| 3,437
|
Transcriptional regulation by runx3
| 18
| 43
| 2.542648
| 0.011002
|
P20618,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25440,P49721,P25788,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,602,287,10,275,44,482,528,172,19,416,183,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,415,2540,1676,831,63,172,2162,1085,416,1357,1088,10,44,287,1819,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,1759,2604,2248,2178,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,-0.3302224903627467,0.010222744193719364,0.37438246142501497,1.759396490717528,1.0960533169755888,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,-0.042002740889055014,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.01588339248816641,-0.35651011446187664,-0.19900296686591165,-0.17280182112563378,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Proteasome core complex beta subunit complex
| 6
| 7
| 2.520817
| 0.011708
|
P20618,P28070,Q99436,P28072,P49721,P49720
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
63,10,275,44,19,183
|
63,10,44,287,183,19,275
|
1.759396490717528,4.857234201516885,2.0636350154112697,0.8392530272685477,1.070417398184814,3.09516261931888,0.890692731740149
| 3,437
|
Proteasome B-type subunit [IPR023333]
| 6
| 7
| 2.520817
| 0.011708
|
P20618,P28070,Q99436,P28072,P49721,P49720
|
Sequence
|
InterPro Family
|
interpro_family
|
63,10,275,44,19,183
|
63,10,44,287,183,19,275
|
1.759396490717528,4.857234201516885,2.0636350154112697,0.8392530272685477,1.070417398184814,3.09516261931888,0.890692731740149
| 3,437
|
Regulation of runx2 expression and activity
| 20
| 45
| 2.493109
| 0.012663
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9UL46,P60900,P62333,Q13309,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,677,183,63,759,602,482,604,364,368
|
528,2480,1339,677,1342,1668,415,1961,831,63,2162,1085,416,1357,1088,10,44,287,1611,3095,2237,2101,183,19,731,2789,645,602,1095,364,649,482,935,1758,2604,604,2752,2178,36,368,275,1124,759,2139,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,-0.09428154235373645,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.7526829888195903,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,0.4262123823488152,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.35651011446187664,0.5038712950051047,-0.4354630136619837,-0.17280182112563378,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.14661461977842807,-0.01588339248816641
| 3,437
|
Hedgehog on state
| 19
| 42
| 2.47861
| 0.01319
|
P28070,Q99436,P49721,Q96J02,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,157,645,649,36,287,44,528,416,415,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1150,1611,2237,2101,2912,183,19,2789,645,602,1095,364,649,482,1758,2604,1628,36,368,2758,157,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.21860961070595744,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,-0.5673604973578883,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,0.03631578405272416,2.341547868171487,0.7104735093783054,-0.4354630136619837,1.1472965125647505,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Stabilization of p53
| 19
| 39
| 2.474303
| 0.01335
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,O96017,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,677,183,63,320,602,482,364,368
|
528,2480,1339,677,1342,1668,415,320,2540,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,36,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.78777240802752,-0.3302224903627467,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Dectin 1 mediated noncanonical nf kb signaling
| 19
| 42
| 2.474231
| 0.013352
|
P28070,Q99436,P49721,O15111,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,27,645,649,36,287,44,528,416,415,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,27,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1094,1095,364,649,482,935,1758,2604,2752,36,368,2922,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,-0.5673604973578883,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Tnfr2 non canonical nf kb pathway
| 19
| 42
| 2.474231
| 0.013352
|
P28070,Q99436,P49721,O15111,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,27,645,649,36,287,44,528,416,415,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,27,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1094,1095,364,649,482,935,1758,2604,2752,36,368,2922,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,-0.5673604973578883,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Abnormal palmar dermatoglyphics
| 10
| 66
| 2.460834
| 0.013861
|
P98175,Q9BTA9,Q9P2D1,P56589,Q9UQ13,P51812,Q96J02,Q13363,Q9Y263,P41227
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
222,1,135,122,203,57,157,124,29,244
|
2726,385,883,1219,2420,1283,3192,2023,2090,1958,2153,2027,2356,1680,2161,1492,835,2098,1899,1821,244,2943,1025,57,122,1026,280,2369,222,782,1502,124,1993,3170,2183,987,1697,426,1841,3097,2381,1925,1842,1512,2957,3196,1575,2998,1581,157,1520,1649,1327,1,2327,2463,2132,135,3223,1473,203,1070,29,1337,2143,2018
|
-0.4354630136619837,0.6846861232304023,0.3484500400782194,0.19260518741836744,-0.27769138081303274,0.16658842023685425,-0.9387496993351647,-0.12044123528532528,-0.14661461977842807,-0.09428154235373645,-0.17280182112563378,-0.12044123528532528,-0.25144761327768334,0.010222744193719364,-0.17280182112563378,0.08846302330909535,0.37438246142501497,-0.14661461977842807,-0.06813541787919085,-0.042002740889055014,0.9420920779153221,-0.5937877925087558,0.2705818269915089,1.8101826910064611,1.2496700320630116,0.2705818269915089,0.8649779587240712,-0.25144761327768334,0.9934516077523754,0.4003032120537953,0.08846302330909535,1.2496700320630116,-0.09428154235373645,-0.8855144491446009,-0.17280182112563378,0.2965498167601974,0.010222744193719364,0.6588880680272334,-0.042002740889055014,-0.7526829888195903,-0.25144761327768334,-0.06813541787919085,-0.042002740889055014,0.08846302330909535,-0.5937877925087558,-0.9387496993351647,0.062395840059970745,-0.6202311111444645,0.062395840059970745,1.1472965125647505,0.08846302330909535,0.03631578405272416,0.16658842023685425,12.741750894706325,-0.22521818684495445,-0.27769138081303274,-0.14661461977842807,1.2240906124858706,-0.9920421587976711,0.1145174430622166,1.0447718492501796,0.2705818269915089,2.54311235991026,0.16658842023685425,-0.14661461977842807,-0.09428154235373645
| 3,437
|
Cellular response to hypoxia
| 19
| 40
| 2.455109
| 0.014084
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,Q15369,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,303,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,3017,36,368,303,1916,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,-0.6466903057401047,2.341547868171487,0.7104735093783054,0.8135178673565373,-0.06813541787919085,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Signaling by the b cell receptor bcr
| 20
| 45
| 2.45439
| 0.014112
|
P28070,Q99436,P49721,O15111,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P62993,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,27,645,649,36,287,44,528,416,415,677,183,63,687,602,482,364,368
|
2934,528,2480,1339,677,1342,27,1668,883,1410,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,687,935,1758,3236,2604,2752,36,368,275,1124,759,1793
|
-0.5937877925087558,0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.3484500400782194,0.1145174430622166,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.4521100613445833,0.3225058562487884,-0.01588339248816641,-1.0720860968906154,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Regulation of ras by gaps
| 18
| 38
| 2.454235
| 0.014118
|
P20618,Q14997,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,36,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,1628,36,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,0.03631578405272416,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Apc c mediated degradation of cell cycle proteins
| 22
| 59
| 2.453727
| 0.014138
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O60566,O75832,O00487,P49720,P20618,Q16763,P60900,Q96DE5,P62333,Q13309,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,414,415,677,183,63,740,602,376,482,604,364,368
|
528,2480,1339,677,1342,1668,1408,414,415,927,893,831,3010,63,2160,2162,1085,416,1357,1088,10,44,287,2688,1611,2237,2101,183,19,2789,977,645,602,1095,364,649,482,935,1758,2053,2604,1691,604,2752,36,368,740,376,2800,275,1124,1526,869,1335,2081,3200,2211,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.1145174430622166,0.6588880680272334,0.6588880680272334,0.3225058562487884,0.3484500400782194,0.37438246142501497,-0.6466903057401047,1.759396490717528,-0.17280182112563378,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,-0.40913022679566735,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.2965498167601974,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.12044123528532528,-0.35651011446187664,0.010222744193719364,0.5038712950051047,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.4262123823488152,0.7104735093783054,-0.4618111582937517,0.890692731740149,0.24460179084386904,0.08846302330909535,0.37438246142501497,0.16658842023685425,-0.12044123528532528,-0.9387496993351647,-0.17280182112563378,0.4262123823488152,-0.01588339248816641
| 3,437
|
Coloboma
| 8
| 52
| 2.439044
| 0.014726
|
Q9BTA9,Q9P2D1,Q9P273,P41227,P61978,Q13363,O60828,Q96EK5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,135,16,244,280,124,182,329
|
820,1874,1140,715,3261,2783,926,182,2681,2090,1958,1680,833,835,1742,244,3331,1235,2044,280,2106,782,689,1503,1166,124,2855,1243,426,3097,1925,484,2611,1512,1569,343,1390,329,1649,1,999,2327,1204,866,2202,2891,2130,16,135,1470,3223,2275
|
0.37438246142501497,-0.06813541787919085,0.21860961070595744,0.4262123823488152,-1.1522536780248447,-0.4618111582937517,0.3225058562487884,1.070417398184814,-0.40913022679566735,-0.14661461977842807,-0.09428154235373645,0.010222744193719364,0.37438246142501497,0.37438246142501497,-0.01588339248816641,0.9420920779153221,-1.5548507048114968,0.19260518741836744,-0.12044123528532528,0.8649779587240712,-0.14661461977842807,0.4003032120537953,0.4521100613445833,0.08846302330909535,0.21860961070595744,1.2496700320630116,-0.5145541510399857,0.19260518741836744,0.6588880680272334,-0.7526829888195903,-0.06813541787919085,0.6072596412110887,-0.35651011446187664,0.08846302330909535,0.062395840059970745,0.7620165773584887,0.14055920679442668,0.78777240802752,0.03631578405272416,12.741750894706325,0.2965498167601974,-0.22521818684495445,0.21860961070595744,0.37438246142501497,-0.17280182112563378,-0.5409493221872759,-0.14661461977842807,3.4697913048737528,1.2240906124858706,0.1145174430622166,-0.9920421587976711,-0.19900296686591165
| 3,437
|
DNA replication
| 24
| 53
| 2.431044
| 0.015055
|
Q9UFC0,O95251,Q9BRT9,P33991,P18858,P27694,Q9UBD5,P49321,P35244,P49736,Q14181,P31350,Q9Y3Z3,Q9Y5B9,Q13416,P33992,Q08945,Q9BQ67,O60870,P33993,P40938,P25205,Q9BRX5,Q9BTE3
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
143,389,553,641,1018,1022,315,173,417,933,56,684,874,877,207,971,983,226,594,233,479,724,1058,519
|
594,389,1887,1675,2230,1018,1965,724,1022,2431,684,641,971,233,417,2234,1609,1971,1359,2360,479,173,1494,2103,933,1824,1978,1912,1164,1760,983,2440,1033,1439,207,56,1562,1768,1631,1179,2452,1706,1519,226,553,1058,519,315,143,2210,2274,874,877
|
0.5038712950051047,0.6846861232304023,-0.06813541787919085,0.010222744193719364,-0.19900296686591165,0.2705818269915089,-0.09428154235373645,0.4262123823488152,0.2705818269915089,-0.27769138081303274,0.4521100613445833,0.4779963367555763,0.2965498167601974,0.9677767865553218,0.6588880680272334,-0.19900296686591165,0.03631578405272416,-0.09428154235373645,0.14055920679442668,-0.25144761327768334,0.6072596412110887,1.0960533169755888,0.08846302330909535,-0.14661461977842807,0.3225058562487884,-0.042002740889055014,-0.09428154235373645,-0.06813541787919085,0.21860961070595744,-0.01588339248816641,0.2965498167601974,-0.27769138081303274,0.2705818269915089,0.1145174430622166,1.0191166070744402,1.8355636276165608,0.062395840059970745,-0.01588339248816641,0.03631578405272416,0.21860961070595744,-0.27769138081303274,0.010222744193719364,0.08846302330909535,0.9934516077523754,0.5555875994245117,0.2705818269915089,0.5814291122334218,0.8135178673565373,1.1985019251998819,-0.17280182112563378,-0.19900296686591165,0.37438246142501497,0.37438246142501497
| 3,437
|
Transcriptional regulation by runx2
| 23
| 57
| 2.430843
| 0.015064
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P31751,Q9UL46,P27361,P28482,P60900,P62333,Q13309,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,677,183,63,323,759,99,477,602,482,604,364,368
|
528,2480,1339,677,1342,1668,415,1961,927,2289,892,1676,893,2028,831,63,2162,1085,416,1357,99,1088,10,44,287,477,323,1611,3095,2237,2101,183,19,731,2789,645,602,1095,364,649,482,935,1758,2245,2604,604,2752,2178,36,368,1197,275,1124,3395,759,2139,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,-0.09428154235373645,0.3225058562487884,-0.22521818684495445,0.3484500400782194,0.010222744193719364,0.3484500400782194,-0.12044123528532528,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,1.402955118769559,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.6072596412110887,0.78777240802752,0.03631578405272416,-0.7526829888195903,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,0.4262123823488152,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.19900296686591165,-0.35651011446187664,0.5038712950051047,-0.4354630136619837,-0.17280182112563378,2.341547868171487,0.7104735093783054,0.21860961070595744,0.890692731740149,0.24460179084386904,-2.4497606170123416,0.4262123823488152,-0.14661461977842807,-0.01588339248816641
| 3,437
|
G1 s dna damage checkpoints
| 19
| 41
| 2.427253
| 0.015214
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,O96017,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,677,183,63,320,602,482,364,368
|
528,2480,1339,677,1342,1668,415,320,2540,831,3010,63,2160,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,36,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.78777240802752,-0.3302224903627467,0.37438246142501497,-0.6466903057401047,1.759396490717528,-0.17280182112563378,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Degradation of dvl
| 18
| 39
| 2.426304
| 0.015253
|
P20618,Q14997,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,36,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,762,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,1628,36,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.4003032120537953,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,0.03631578405272416,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Proteasome core complex
| 6
| 14
| 2.422059
| 0.015433
|
P20618,P28070,Q99436,P28072,P49721,P49720
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
63,10,275,44,19,183
|
1342,63,2162,1085,416,1357,1088,10,44,287,183,19,602,275
|
0.14055920679442668,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,1.070417398184814,3.09516261931888,0.5038712950051047,0.890692731740149
| 3,437
|
Proteasome, subunit alpha/beta [IPR001353]
| 6
| 14
| 2.422059
| 0.015433
|
P20618,P28070,Q99436,P28072,P49721,P49720
|
Sequence
|
InterPro Family
|
interpro_family
|
63,10,275,44,19,183
|
1342,63,2162,1085,416,1357,1088,10,44,287,183,19,602,275
|
0.14055920679442668,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,1.070417398184814,3.09516261931888,0.5038712950051047,0.890692731740149
| 3,437
|
Degradation of axin
| 18
| 37
| 2.412098
| 0.015861
|
P20618,Q14997,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,36,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,36,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Defective cftr causes cystic fibrosis
| 18
| 42
| 2.406314
| 0.016114
|
P20618,Q14997,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,36,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,1802,415,2539,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,1751,602,1095,364,649,482,1758,2604,36,368,275,1124,3000,2675,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,-0.042002740889055014,0.6588880680272334,-0.3302224903627467,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,-0.01588339248816641,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,-0.6202311111444645,-0.3828126439803247,0.4262123823488152,-0.01588339248816641
| 3,437
|
Mapk6 mapk4 signaling
| 20
| 50
| 2.403547
| 0.016237
|
P28070,Q99436,Q16512,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,Q16181,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,657,19,645,649,36,287,44,528,416,415,677,183,63,602,482,609,364,368
|
528,2480,1339,677,1342,1479,1668,415,3336,927,3050,2786,831,63,2849,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,2169,1095,364,649,482,2499,1758,1990,2604,36,368,609,657,275,1124,2403,2134,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.08846302330909535,0.010222744193719364,0.6588880680272334,-1.6357045003570223,0.3225058562487884,-0.6996557465222012,-0.4618111582937517,0.37438246142501497,1.759396490717528,-0.5145541510399857,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,-0.17280182112563378,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.3039496266010951,-0.01588339248816641,-0.09428154235373645,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.5038712950051047,0.4779963367555763,0.890692731740149,0.24460179084386904,-0.25144761327768334,-0.14661461977842807,0.4262123823488152,-0.01588339248816641
| 3,437
|
Epithelial cell development
| 12
| 44
| 2.385476
| 0.017057
|
Q8WX93,P35241,Q8TEU7,Q9Y4G8,P19022,Q9UDY2,O14974,Q15382,P62820,Q00534,P11047,Q4LE39
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
262,352,5,9,322,179,318,139,113,365,117,165
|
318,2420,1013,1412,3113,531,117,1676,968,683,969,322,572,832,833,3094,352,1358,395,1428,731,2039,2040,1370,1981,113,365,689,1622,510,1696,139,165,1702,5,262,2926,1530,2867,179,2780,9,2725,818
|
0.78777240802752,-0.27769138081303274,0.2705818269915089,0.1145174430622166,-0.7792194448781685,0.5555875994245117,1.2752402417749096,0.010222744193719364,0.2965498167601974,0.4521100613445833,0.2965498167601974,0.78777240802752,0.5297350212533344,0.37438246142501497,0.37438246142501497,-0.7526829888195903,0.736250302444436,0.14055920679442668,0.6846861232304023,0.1145174430622166,0.4262123823488152,-0.12044123528532528,-0.12044123528532528,0.14055920679442668,-0.09428154235373645,1.3008012987680424,0.7104735093783054,0.4521100613445833,0.03631578405272416,0.5814291122334218,0.010222744193719364,1.1985019251998819,1.1216796679268493,0.010222744193719364,8.409153722165714,0.9163974154088532,-0.5673604973578883,0.08846302330909535,-0.5145541510399857,1.0960533169755888,-0.4354630136619837,5.02954103940884,-0.40913022679566735,0.4003032120537953
| 3,437
|
Regulation of hmox1 expression and activity
| 19
| 47
| 2.380538
| 0.017287
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,Q13309,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,677,183,63,602,482,604,364,368
|
528,2480,1339,677,1342,1668,415,3215,831,1813,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,935,1373,2302,1987,1758,2604,604,2752,1628,36,368,3246,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,-0.9920421587976711,0.37438246142501497,-0.042002740889055014,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,0.14055920679442668,-0.22521818684495445,-0.09428154235373645,-0.01588339248816641,-0.35651011446187664,0.5038712950051047,-0.4354630136619837,0.03631578405272416,2.341547868171487,0.7104735093783054,-1.0987950297512232,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Abc transporter disorders
| 18
| 44
| 2.37663
| 0.017472
|
P20618,Q14997,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,36,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,3108,1342,1668,1802,415,2539,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,1751,602,1095,364,649,482,1758,2604,36,368,275,1124,3000,1720,2675,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,-0.7792194448781685,0.14055920679442668,0.010222744193719364,-0.042002740889055014,0.6588880680272334,-0.3302224903627467,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,-0.01588339248816641,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,-0.6202311111444645,0.010222744193719364,-0.3828126439803247,0.4262123823488152,-0.01588339248816641
| 3,437
|
Cross presentation of soluble exogenous antigens endosomes
| 18
| 38
| 2.365177
| 0.018021
|
P20618,Q14997,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,36,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,36,368,275,1124,2835,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,-0.4881748174530137,0.4262123823488152,-0.01588339248816641
| 3,437
|
Regulation of mrna stability by proteins that bind au rich elements
| 23
| 64
| 2.359932
| 0.018278
|
P28070,Q99436,P49721,P55036,P62195,Q01105,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,Q92973,P20618,Q14103,Q92945,P60900,P39687,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,31,36,287,44,528,416,415,677,183,61,63,691,240,602,599,482,364,368
|
528,2480,1339,677,1342,1479,1668,415,2348,3336,1888,1733,3050,831,63,2162,1085,416,1357,1088,10,44,287,1424,898,1611,599,2237,2101,183,19,2789,645,602,1095,364,649,482,1028,31,1620,1987,2642,1758,2604,2107,691,36,368,1506,2057,2445,3195,240,61,275,1124,2929,2204,2129,1655,759,1793,1274
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.08846302330909535,0.010222744193719364,0.6588880680272334,-0.25144761327768334,-1.6357045003570223,-0.06813541787919085,-0.01588339248816641,-0.6996557465222012,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.1145174430622166,0.3484500400782194,0.03631578405272416,0.5038712950051047,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.2705818269915089,2.467578902400475,0.03631578405272416,-0.09428154235373645,-0.3828126439803247,-0.01588339248816641,-0.35651011446187664,-0.14661461977842807,0.4521100613445833,2.341547868171487,0.7104735093783054,0.08846302330909535,-0.12044123528532528,-0.27769138081303274,-0.9387496993351647,0.9677767865553218,1.7847936603664607,0.890692731740149,0.24460179084386904,-0.5673604973578883,-0.17280182112563378,-0.14661461977842807,0.03631578405272416,0.4262123823488152,-0.01588339248816641,0.19260518741836744
| 3,437
|
Auf1 hnrnp d0 binds and destabilizes mrna
| 19
| 42
| 2.357123
| 0.018417
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q14103,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,677,183,63,691,602,482,364,368
|
528,2480,1339,677,1342,1668,415,3336,1888,1733,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1620,1758,2604,691,36,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,-1.6357045003570223,-0.06813541787919085,-0.01588339248816641,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.03631578405272416,-0.01588339248816641,-0.35651011446187664,0.4521100613445833,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Degradation of gli1 by the proteasome
| 19
| 42
| 2.355509
| 0.018497
|
P28070,Q99436,P49721,Q96J02,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,157,645,649,36,287,44,528,416,415,677,183,63,602,482,364,368
|
528,2480,1339,677,1342,1668,415,3050,2786,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,935,1758,2604,2752,36,368,157,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,-0.6996557465222012,-0.4618111582937517,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,1.1472965125647505,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Dna templated transcription elongation
| 8
| 46
| 2.347158
| 0.018917
|
O14776,P19447,Q92541,Q8WX92,P13984,P18615,Q14241,P18074
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,193,142,213,171,18,208,150
|
1725,2,1140,1954,1283,389,3167,171,150,18,193,1819,234,2295,1495,3074,2746,542,2644,3120,208,1244,1916,2755,2859,1106,1839,742,2758,659,745,1452,550,2257,375,1847,213,142,2664,998,2266,2009,1204,707,920,877
|
-0.01588339248816641,11.465227444473113,0.21860961070595744,-0.09428154235373645,0.16658842023685425,0.6846861232304023,-0.8855144491446009,1.0960533169755888,1.1729039116516042,3.1951985716164666,1.0447718492501796,-0.042002740889055014,0.9677767865553218,-0.22521818684495445,0.08846302330909535,-0.7261617112368798,-0.4354630136619837,0.5555875994245117,-0.3828126439803247,-0.7792194448781685,1.0191166070744402,0.19260518741836744,-0.06813541787919085,-0.4354630136619837,-0.5145541510399857,0.24460179084386904,-0.042002740889055014,0.4262123823488152,-0.4354630136619837,0.4779963367555763,0.4262123823488152,0.1145174430622166,0.5555875994245117,-0.19900296686591165,0.7104735093783054,-0.042002740889055014,1.0191166070744402,1.1985019251998819,-0.3828126439803247,0.2965498167601974,-0.19900296686591165,-0.09428154235373645,0.21860961070595744,0.4521100613445833,0.3484500400782194,0.37438246142501497
| 3,437
|
Regulation of runx3 expression and activity
| 17
| 38
| 2.342312
| 0.019165
|
P20618,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,415,1676,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,2178,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.010222744193719364,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,-0.17280182112563378,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Asymmetric localization of pcp proteins
| 18
| 39
| 2.333053
| 0.019645
|
P20618,Q14997,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,36,602,287,10,275,44,482,528,416,19,183,415,677,364,645,368,649
|
528,2480,1339,677,762,1342,1668,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,2856,36,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.4003032120537953,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,-0.5145541510399857,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Proteasome
| 17
| 35
| 2.327441
| 0.019942
|
P20618,Q14997,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
63,36,602,287,10,275,44,482,528,416,19,183,677,364,645,368,649
|
528,2480,677,1342,1668,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,1758,2604,36,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Downstream signaling events of b cell receptor bcr
| 19
| 43
| 2.324981
| 0.020073
|
P28070,Q99436,P49721,O15111,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P60900,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,27,645,649,36,287,44,528,416,415,677,183,63,602,482,364,368
|
2934,528,2480,1339,677,1342,27,1668,883,415,831,63,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,935,1758,3236,2604,2752,36,368,275,1124,759,1793
|
-0.5937877925087558,0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,2.6185830710263986,0.010222744193719364,0.3484500400782194,0.6588880680272334,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-1.0720860968906154,-0.35651011446187664,-0.4354630136619837,2.341547868171487,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Cyclin a cdk2 associated events at s phase entry
| 19
| 44
| 2.322726
| 0.020194
|
P28070,Q99436,P49721,P55036,P62195,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,P31751,P60900,P62333,Q13309,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,287,44,528,416,415,677,183,63,323,602,482,604,364,368
|
528,2480,1339,677,1342,1668,415,892,831,3010,63,2160,2162,1085,416,1357,1088,10,44,287,323,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,935,1758,2440,2604,604,2752,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.3484500400782194,0.37438246142501497,-0.6466903057401047,1.759396490717528,-0.17280182112563378,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.78777240802752,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.27769138081303274,-0.35651011446187664,0.5038712950051047,-0.4354630136619837,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Abc family proteins mediated transport
| 21
| 53
| 2.315808
| 0.020569
|
P28070,Q99436,P49721,P55036,P62195,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9NUT2,P60900,O15439,P62333,P56589,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,645,649,36,287,44,528,416,415,677,183,63,84,602,593,482,122,364,368
|
528,2480,1339,677,1342,593,1668,3388,1802,415,2539,1016,3386,831,1230,63,2162,1085,416,1357,1088,10,44,287,2232,1611,1821,2237,2101,183,19,2789,645,1751,122,602,1095,364,649,482,1758,2604,36,368,3100,275,1124,3000,955,84,2675,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.5038712950051047,0.010222744193719364,-2.258963766553734,-0.042002740889055014,0.6588880680272334,-0.3302224903627467,0.2705818269915089,-2.231747507312549,0.37438246142501497,0.19260518741836744,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,-0.19900296686591165,0.03631578405272416,-0.042002740889055014,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,-0.01588339248816641,1.2496700320630116,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,-0.01588339248816641,-0.35651011446187664,2.341547868171487,0.7104735093783054,-0.7526829888195903,0.890692731740149,0.24460179084386904,-0.6202311111444645,0.3225058562487884,1.5559205669344653,-0.3828126439803247,0.4262123823488152,-0.01588339248816641
| 3,437
|
Self injurious behavior
| 8
| 44
| 2.305537
| 0.021137
|
Q9BTA9,P55795,Q9NS87,P41227,P51812,O95155,Q06787,Q01105
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,76,121,244,57,153,184,31
|
1874,2149,153,1959,2424,322,1492,477,1682,2097,1819,244,2947,57,76,1373,688,31,842,651,184,3236,1503,1763,1765,785,1106,742,3097,1925,2611,1112,3196,2315,2193,1194,2769,488,2459,1,2624,121,1470,3106
|
-0.06813541787919085,-0.17280182112563378,1.1472965125647505,-0.09428154235373645,-0.27769138081303274,0.78777240802752,0.08846302330909535,0.6072596412110887,0.010222744193719364,-0.14661461977842807,-0.042002740889055014,0.9420920779153221,-0.5937877925087558,1.8101826910064611,1.5813845281691368,0.14055920679442668,0.4521100613445833,2.467578902400475,0.37438246142501497,0.4779963367555763,1.070417398184814,-1.0720860968906154,0.08846302330909535,-0.01588339248816641,-0.01588339248816641,0.4003032120537953,0.24460179084386904,0.4262123823488152,-0.7526829888195903,-0.06813541787919085,-0.35651011446187664,0.24460179084386904,-0.9387496993351647,-0.22521818684495445,-0.17280182112563378,0.21860961070595744,-0.4354630136619837,0.6072596412110887,-0.27769138081303274,12.741750894706325,-0.35651011446187664,1.2752402417749096,0.1145174430622166,-0.7526829888195903
| 3,437
|
Protein modification by small protein removal
| 17
| 50
| 2.286673
| 0.022215
|
Q93008,Q99627,P19474,Q9Y4E8,Q9NWV8,Q9Y6J9,P45974,Q9UNS2,Q15020,Q9P275,Q96K76,Q9UBW8,Q96FW1,Q96J02,Q96ES7,Q86UV5,P51784
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
663,463,206,676,439,412,601,442,369,276,551,255,23,157,251,427,64
|
1340,677,2421,1417,927,206,2034,2817,601,2366,64,1748,1751,2297,902,1989,2503,1381,787,369,2505,1564,1998,427,1845,2515,1324,663,1194,251,23,157,551,1648,1651,2828,463,1125,1587,2803,1941,439,1789,2269,276,255,442,676,1537,412
|
0.14055920679442668,0.4521100613445833,-0.27769138081303274,0.1145174430622166,0.3225058562487884,1.0191166070744402,-0.12044123528532528,-0.4881748174530137,0.5038712950051047,-0.25144761327768334,1.759396490717528,-0.01588339248816641,-0.01588339248816641,-0.22521818684495445,0.3484500400782194,-0.09428154235373645,-0.3039496266010951,0.14055920679442668,0.4003032120537953,0.7104735093783054,-0.3039496266010951,0.062395840059970745,-0.09428154235373645,0.6588880680272334,-0.042002740889055014,-0.3039496266010951,0.16658842023685425,0.4779963367555763,0.21860961070595744,0.9420920779153221,2.8195382437120737,1.1472965125647505,0.5555875994245117,0.03631578405272416,0.03631578405272416,-0.4881748174530137,0.6330792667297674,0.24460179084386904,0.062395840059970745,-0.4618111582937517,-0.06813541787919085,0.6588880680272334,-0.01588339248816641,-0.19900296686591165,0.890692731740149,0.9420920779153221,0.6588880680272334,0.4779963367555763,0.08846302330909535,0.6846861232304023
| 3,437
|
Positive regulation of cellular protein catabolic process
| 23
| 53
| 2.276903
| 0.022792
|
Q8NEZ5,O43765,Q9Y4X5,Q05397,Q9H000,Q9ULT8,Q9UNN5,P62195,Q9NZL4,Q4ZIN3,Q8IXJ6,O75832,P15311,Q06787,Q9UBS8,Q96HY6,Q9H270,Q9UMX0,P35241,P45974,Q9BW61,P62333,P62191
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
261,7,411,269,17,560,561,649,178,425,50,415,683,184,73,620,754,632,352,601,100,482,364
|
7,926,1484,415,889,3326,3333,1349,2155,683,831,832,352,1611,2237,601,1686,1427,2912,731,2984,977,2494,1751,364,649,482,1301,269,184,1916,425,3316,50,261,620,2710,1585,100,1201,17,754,178,2269,73,1533,3136,560,632,2139,561,411,1074
|
5.471572567824065,0.3225058562487884,0.08846302330909535,0.6588880680272334,0.3484500400782194,-1.5279234016007261,-1.5817900434130296,0.14055920679442668,-0.17280182112563378,0.4521100613445833,0.37438246142501497,0.37438246142501497,0.736250302444436,0.03631578405272416,-0.19900296686591165,0.5038712950051047,0.010222744193719364,0.1145174430622166,-0.5673604973578883,0.4262123823488152,-0.6202311111444645,0.2965498167601974,-0.3039496266010951,-0.01588339248816641,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.16658842023685425,0.890692731740149,1.070417398184814,-0.06813541787919085,0.6588880680272334,-1.4203362219262978,1.9370073166859738,0.9163974154088532,0.5038712950051047,-0.40913022679566735,0.062395840059970745,1.402955118769559,0.21860961070595744,3.2451792675084628,0.4262123823488152,1.0960533169755888,-0.19900296686591165,1.6577255052032591,0.08846302330909535,-0.8057709474338041,0.5555875994245117,0.5038712950051047,-0.14661461977842807,0.5555875994245117,0.6846861232304023,0.2705818269915089
| 3,437
|
Signaling by hedgehog
| 23
| 59
| 2.245895
| 0.024711
|
P28070,Q99436,P49721,Q96J02,P55036,P62195,Q9BUF5,Q14997,P28074,P28072,O00231,P25788,O75832,O00487,P49720,P20618,Q9UL46,Q9BVA1,P60900,P04350,P62333,P62191,Q15008
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
10,275,19,157,645,649,437,36,287,44,528,416,415,677,183,63,759,357,602,475,482,364,368
|
528,2480,1339,677,1342,1668,415,475,2976,829,1890,3050,2786,831,63,2162,1085,416,1357,1088,10,44,287,1968,1150,1611,2237,2101,2912,183,19,731,2789,645,1751,602,1095,364,649,482,935,1097,3328,1758,2604,2752,1628,36,368,2758,2708,157,275,1124,437,357,2675,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.6072596412110887,-0.6202311111444645,0.37438246142501497,-0.06813541787919085,-0.6996557465222012,-0.4618111582937517,0.37438246142501497,1.759396490717528,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,-0.09428154235373645,0.21860961070595744,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,-0.5673604973578883,1.070417398184814,3.09516261931888,0.4262123823488152,-0.4618111582937517,0.4779963367555763,-0.01588339248816641,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,0.24460179084386904,-1.5279234016007261,-0.01588339248816641,-0.35651011446187664,-0.4354630136619837,0.03631578405272416,2.341547868171487,0.7104735093783054,-0.4354630136619837,-0.40913022679566735,1.1472965125647505,0.890692731740149,0.24460179084386904,0.6588880680272334,0.736250302444436,-0.3828126439803247,0.4262123823488152,-0.01588339248816641
| 3,437
|
Actin filaments
| 29
| 53
| 2.233163
| 0.025538
|
Q8WX93,P35579,Q9NYL9,Q9BTX1,O75718,Q9NVA1,O43707,P35580,P12814,Q15942,Q9NR12,Q6WCQ1,Q99439,P17812,Q9P0K7,Q9UHB6,Q9UI12,P42694,Q69YQ0,O00151,Q15417,Q9UPN3,O14974,Q9HCD5,P09493,Q6P4Q7,Q16181,Q96IZ0,Q9Y6E2
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
262,505,134,11,137,20,635,897,393,156,557,944,295,769,440,441,708,418,426,924,580,871,318,756,828,373,609,252,526
|
924,318,635,1412,3353,137,1732,3278,828,393,769,1680,1021,505,897,1554,418,2945,934,1029,1499,1913,1914,2951,2648,580,156,609,1445,426,373,2609,944,3060,262,2768,2396,252,295,1124,11,756,557,1788,20,134,440,441,1866,2584,708,871,526
|
0.3225058562487884,0.78777240802752,0.4779963367555763,0.1145174430622166,-1.7977284331011252,1.1985019251998819,-0.01588339248816641,-1.2325420451953735,0.37438246142501497,0.6846861232304023,0.4003032120537953,0.010222744193719364,0.2705818269915089,0.5814291122334218,0.3484500400782194,0.062395840059970745,0.6588880680272334,-0.5937877925087558,0.3225058562487884,0.2705818269915089,0.08846302330909535,-0.06813541787919085,-0.06813541787919085,-0.5937877925087558,-0.3828126439803247,0.5297350212533344,1.1472965125647505,0.5038712950051047,0.1145174430622166,0.6588880680272334,0.7104735093783054,-0.35651011446187664,0.3225058562487884,-0.6996557465222012,0.9163974154088532,-0.4354630136619837,-0.25144761327768334,0.9420920779153221,0.8392530272685477,0.24460179084386904,4.585988652878638,0.4262123823488152,0.5555875994245117,-0.01588339248816641,3.0701379402256634,1.2240906124858706,0.6588880680272334,0.6588880680272334,-0.042002740889055014,-0.3302224903627467,0.4521100613445833,0.37438246142501497,0.5814291122334218
| 3,437
|
Scf skp2 mediated degradation of p27 p21
| 18
| 42
| 2.2162
| 0.026678
|
P20618,P60900,P28074,P28070,Q99436,P28072,P62333,O00231,P25788,P49721,P49720,Q13309,O75832,O00487,P62191,P55036,Q15008,P62195
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
63,602,287,10,275,44,482,528,416,19,183,604,415,677,364,645,368,649
|
528,2480,1339,677,1342,1668,415,892,831,3010,63,2160,2162,1085,416,1357,1088,10,44,287,1611,2237,2101,183,19,2789,645,602,1095,364,649,482,935,1758,2604,604,2752,368,275,1124,759,1793
|
0.5555875994245117,-0.3039496266010951,0.14055920679442668,0.4521100613445833,0.14055920679442668,0.010222744193719364,0.6588880680272334,0.3484500400782194,0.37438246142501497,-0.6466903057401047,1.759396490717528,-0.17280182112563378,-0.17280182112563378,0.24460179084386904,0.6588880680272334,0.14055920679442668,0.24460179084386904,4.857234201516885,2.0636350154112697,0.8392530272685477,0.03631578405272416,-0.19900296686591165,-0.14661461977842807,1.070417398184814,3.09516261931888,-0.4618111582937517,0.4779963367555763,0.5038712950051047,0.24460179084386904,0.7104735093783054,0.4779963367555763,0.6072596412110887,0.3225058562487884,-0.01588339248816641,-0.35651011446187664,0.5038712950051047,-0.4354630136619837,0.7104735093783054,0.890692731740149,0.24460179084386904,0.4262123823488152,-0.01588339248816641
| 3,437
|
Regulation of actin filament length
| 22
| 44
| 2.213556
| 0.026859
|
Q9NYL9,O00165,Q9UQB8,P07737,Q9NUQ9,Q9UHB6,Q01082,O15020,P58546,Q92747,P62993,O15144,Q7L576,O95429,Q9UEY8,P35241,Q14247,P50552,Q9UJU6,P59998,P47756,Q13813
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,256,13,30,297,441,782,300,197,461,687,566,326,74,497,352,844,235,383,480,727,605
|
256,300,566,2085,2344,2025,74,30,352,1358,1610,2943,727,235,2041,197,480,1300,1754,2370,687,782,1987,1834,1375,1765,605,2055,844,1445,3313,326,1456,461,913,297,134,497,441,383,13,2804,1273,2281
|
0.9163974154088532,0.8135178673565373,0.5297350212533344,-0.14661461977842807,-0.25144761327768334,-0.12044123528532528,1.632286948462474,2.467578902400475,0.736250302444436,0.14055920679442668,0.03631578405272416,-0.5937877925087558,0.4262123823488152,0.9677767865553218,-0.12044123528532528,1.0447718492501796,0.6072596412110887,0.16658842023685425,-0.01588339248816641,-0.25144761327768334,0.4521100613445833,0.4003032120537953,-0.09428154235373645,-0.042002740889055014,0.14055920679442668,-0.01588339248816641,0.5038712950051047,-0.12044123528532528,0.37438246142501497,0.1145174430622166,-1.3934703658292524,0.78777240802752,0.1145174430622166,0.6330792667297674,0.3484500400782194,0.8392530272685477,1.2240906124858706,0.6072596412110887,0.6588880680272334,0.7104735093783054,4.239890873327849,-0.4618111582937517,0.19260518741836744,-0.19900296686591165
| 3,437
|
Subsets and Splits
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