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"Pseudopalisading" arrangement of malignant cells is characteristic of:
"The highest grade tumor of astrocytoma, known as glioblastoma, has a histologic appearance similar to anaplastic astrocytoma with the additional features of necrosis and vascular or endothelial cell proliferation and pseudo-palisading nuclei." Glioblastoma is type of infiltrating astrocytoma (Classified as Grade 4). ...
1
Glioblastoma
Ependymoma
Oligodendroglioma
Medulloblastoma
Pathology
null
2b914563-e45e-4c5b-a956-898049c68022
single
Steeple sign is seen in
Acute laryngotracheobronchitis or croup is a viral infection caused by parainfluenza type 1, 2, and sometimes 3. The critical area involved is subglottic larynx producing oedema with stridor and respiratory distress. X-ray (PA view) larynx shows typical "steeple sign" but X-rays are avoided as any manipulation may prec...
1
Croup
Acute epiglottitis
Laryngomalacia
Quinsy
ENT
Larynx
9ff1b39e-3523-4c43-aeb4-2e8190f093bd
single
SIADH is caused by all EXCEPT :
Drugs causing syndrome of inappropriate ADH (SIADH) secretion
3
Vincristine
Vinblastine
Actinomycin D
Cyclophosphamide
Pharmacology
null
f5e1e31e-64d3-4a5c-b114-9bfb94f5a0d2
multi
VHL gene is located on?
VHL gene mutation is associated with neurocutaneous syndrome Von - Hipple - Lindau disease. It is associated with Hemangioblastomas, cysts, Renal cell carcinoma.
2
3q
3p
5p
5q
Pathology
null
5ff1c598-70b9-41c8-a40d-7b1c13390466
single
Cetuximab (an EGFR antagonist) can be used in ?
Ans. is 'a' i.e., Palliation in head neck cancer Uses of Cetuximab Head and neck cancer Colorectal cancer
1
Palliation in head and neck cancer
Anal canal ca
Gastric ca
Lung ca
Pharmacology
null
3da47ba9-a983-4103-8f18-96f71db8460c
multi
Causes of papillary necrosis in kidney are/is:
Ans. d (All). (Ref. Robbin's, Pathology, 6th/pg.924)CAUSES OF PAPILLARY NECROSIS (mnemonic--POSTCARD):# Pyelonephritis# Obstructive uropathy# Sickle cell disease# TB and trauma, tubular necrosis, transplant rejection# Cirrhosis (alcoholism, coagulopathy)# Analgesics# Renal vein thrombosis# Diabetes, Dehydration
4
Diabetes mellitus
Sickle cell disease
Analgesic abuse
All
Pathology
Kidney
5e9d17bb-fb95-4fd5-94c7-762219f408c1
multi
'Heliotrope rash' over face is seen in
Dermatomyositis a. Heliotrope erythema and oedema of the periorbital skin are seen in dermatomyositis, b. Dermatomyositis is a well established cutaneous marker of interval malignancy. c. About 10% of all patients of dermatomyositis have an underlying malignancy. d. The most common malignancies associated with dermatom...
2
Systemic sclerosis
Dermatomyositis
Systemic lupus erythematosus
Rheumatoid ahritis
Physiology
All India exam
521095cd-26b7-45ad-b688-2d2355415336
single
Hypeension in childhood typically complicates
Hypeension complicates 60-70% of post-streptococcal glomerulonephritis and it can result in cardiac failure and hypeensive encephalopathy.Post-streptococcal glomerulonephritis- Labile Hypeension as it resolves within 4-6 weeks of onset.In minimal change nephrotic syndrome, hypeension is absent.PSGN occurs 1-3 weeks fol...
1
Post-streptococcal glomerulonephritis
Minimal change disease
Appendicitis
Peptic ulceration
Pediatrics
All India exam
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multi
29-year-old male with episodic abdominal pain and stress-induced edema of the lips, the tongue, and occasionally the larynx is likely to have low functional or absolute levels of which of the following proteins?
Complement activity, which results from the sequential interaction of a large number of plasma and cell-membrane proteins, plays an impoant role in the inflammatory response. The classic pathway of complement activation is initiated by an antibody-antigen interaction. The first complement component (C1, a complex compo...
4
C5A (Complement cascade)
T cell receptor, a chain
Cyclooxygenase
C1 esterase inhibitor
Biochemistry
null
35c1ba74-e05e-4e96-9772-6c7b74e3d588
multi
Colonic Polyp that has maximum chance of malignant change?
Ans. B. Adenomatous polyp.. (Ref. Robbin's pathology 8th/pg. 618)Robbin's pathology 8th/pg. 618....."Adenomas are neoplastic polyps that range from small, often pedunculated, tumors to large lesions that are usually sessile. Incidence of adenomas in the small intestine is very low compared to those arise in the colon.T...
2
Hyperplastic polyp
Adenomatous polyp
Juvenile polyp
Polyp of Peutzeger syndrome
Pathology
G.I.T.
6e1702ad-dfeb-4274-95de-052628a319d6
single
13, years old boy, the LEAST common cause of proximal lytic lesion of the head of the femur is -
If multiple myeloma occurs as a solitary lesion it is known as Plasmacytoma Age gp is 6th-7th decade, Rare before 40yrs of age So the lytic lesion in a 13 yrs old boy cannot be a plasmacytoma
1
Plasmacytoma
Metastasis
Histiocytosis
Bone tumour
Orthopaedics
null
96c23a4f-3ee1-41ea-91b8-79bdb6ce6df3
single
Venous drainage from neurohypophysis is routed through all of the following except -
There are three routes for venous drainage of neurohypophysis :- To adenohypophysis via long and short portal vessels. Into dural venous sinuses via inferior hypophyseal veins. To hypothalamus via capillaries passing to median eminence.
2
Portal vessels to adenohypophysis
Superior hypophyseal veins to ventricular tanycytes
Inferior hypophyseal veins to dural venous sinuses
Capillaries to median eminence and hypothalamus
Anatomy
null
5672e9f4-7e9a-40bf-8d7e-477f6823bccf
multi
Which orexin receptor antagonist is approved for treatment of insomnia ?
Suvorexant MOA : Orexin 1 and 2 receptors inhibitor Orexin antagonist enhance REM and non-REM sleep. Suvorexant decreases sleep onset latency Dose : 10-mg dose within 30 min of going to bed S/E : Daytime somnolence
1
Suvorexant
Doxepin
Ritanserin
Agomelatine
Pharmacology
Sedative-Hypnotics and Parkinsonism
f8227ae2-5dc5-4922-b2fa-e27fb5306691
single
Contraindication of induction of labour among the following is
Methods to induce or augment labor are contraindicated by most conditions that preclude spontaneous labor or delivery. The few maternal contraindications are related toPrior uterine incisionType contracted or distoed pelvic anatomy,Abnormally implanted placentas, and Uncommon conditions such as active genital herpes in...
1
Contracted pelvis
Bad obstetrical history
Diabetes
Hea disease
Gynaecology & Obstetrics
General obstetrics
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single
Contraindication for applying forceps: March 2009
Ans. D: CPDMnemonic for FORCEPS:Favourable head position and station Open os (fully dilated)Ruptured membranesContractions present and Consent Engaged head, Empty bladderPelvimetry-no major CPDStirrups, lithotomy positionThe following are contraindications to forceps-assisted vaginal deliveries:Any contraindication to ...
4
Crowning of head
Head station +1
Maternal cardiac disease
CPD
Gynaecology & Obstetrics
null
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single
Peau d’orange appearance is due to -
Phenomena resulting from lymphatic obstruction in advanced breast cancer 1. Peaud* orange  Peau d' orange is due to cutaneous lymphatic edema, where the infiltrated skin is tethered by the sweat ducts, it cannot swell, leading to an appearance like orange skin. Occasionally it may be seen in a chronic abscess.  2. Canc...
3
Intra-epithelial cancer
Sub-epidermal cancer
Lymphatic permeation
Vascular embolization
Surgery
null
fa74cf8e-6c89-4000-8191-4b335f9376ad
single
Periodontal diseases associated with neutrophil disorders include
null
4
Acute necrotizing ulcerative gingivitis
Localized juvenile periodontitis
Rapidly progressive periodontitis
All the above
Dental
null
e9a5635b-3345-4dca-856b-6d756002c379
multi
A 30 year old, para two, with two live children has menorrhagia for 2 years. She was ligated 4 years back. On investigation she is found to have a 2 cm X 2 cm submucous myoma. What will be the best management option for her :
Total abdominal hysterectomy
1
Total abdominal hysterectomy
Danazol 400mg twice daily for 3 months
Gn RH analogues
Hysteroscopic myoma resection
Gynaecology & Obstetrics
null
d1e0bec3-88b2-4e94-ac57-57e1015bcade
multi
Which of the following drug is used for hyperkalemia?
Calcium gluconate is used to decrease potassium toxicity along with insulin. Calcium chloride is 2nd choiceRef:
1
Calcium gluconate
Glucagon
Sodium phosphate
Chloride salts
Pharmacology
General pharmacology
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single
Purtscher retinopathy is seen in patients with -
Ans. is 'c' i.e., Head trauma Purtscher retinopathyo Occurrence of bilateral patches of retinal whitening and hemorrhage around the optic disc in patients who suffered massive head trauma was first described by Purtscher and is called Purtscher retinopathy.
3
Complication of chronic pancreatitis
Occlusion of anterior retinal artery
Head trauma
Diabetes mellitus
Ophthalmology
Traumatic Lesions
ec337e61-0883-4ab3-aa51-636b30ac89aa
single
Radial Keratoneuritis is seen in
(All of the above) (106- Khurana 4th)ACANTHAMOEBA KERATITIS (Protozoal)1. Initial-lesions of acanthamoeba Keratitis are in the form of limbitis, coarse, opaque streakes fine epithelial and subepithelial opacities and radial -kerato- neuritis in the form of infiltrates along coreal nerves2. Advanced cases show a central...
4
Acanthamoeba
Herpes-simplex
Neuroparalytic
All of the above
Ophthalmology
Cornea
87d78d59-f6b7-4c80-ba5e-62a466fe9428
multi
A 5-year-old girl begins developing secondary sexual characteristics, including pubic hair growth and breast development. Her concerned parents bring her to the pediatrician for evaluation. An abdominal ultrasound examination reveals an ovarian mass. The mass is resected and pathologic examination reveals it to be a gr...
A young patient presenting with precocious pubey and an ovarian mass is likely to have a granulosa cell tumor. Call-Exner bodies, small follicles filled with eosinophilic secretion, are an impoant diagnostic feature. Signet-ring cells are seen in Krukenberg tumors (bilateral metastatic involvement of the ovaries by a s...
2
Signet-ring cells
Call-Exner bodies
Schiller-Duval bodies
Transitional cell epithelium
Pathology
Ovaries & prostate gland
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multi
LH peak occurs how many hours before ovulation ?
Ans.B.)12-24 hours Ovulation occurs 34 to 36 hours after the onset of the LH surge and about 10 to 12 hours after the LH peak.
1
36-48 hrs.
12-24 hrs.
48-72 hrs.
72-96 hrs.
Physiology
null
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single
Which one of the following is not a special incidence rate-
Ans. is 'd' i.e., Standardized moality rate Special incidence rates i) Attack rate (case rate) ii) Secondary attack rate iii) Hospital admission rate
4
Attack rate
Secondary attack rate
Hospital admission rate
Standardized moality rate
Social & Preventive Medicine
null
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single
In case control study, the risk is calculated by?
Ans. is 'c' i.e., Cross product ratio o Risk in case control study is calculated by odds ratio (cross product ratio).
3
Relative risk
Attributable risk
Cross product ratio
None
Social & Preventive Medicine
null
4f1d8f4f-d7d0-4a8c-b16a-b6b489a40362
multi
Rotterdam criteria are used to evaluate -
Answer- C. PCOSRotterdam criteriaTwo of the following three criteria are required :Oligo/anovulationHyperandrogenismClinical (hirsutism or less commonly male pattern alopecia) orBiochemical (raised FAI or free testosterone)Polycystic ovaries on ultrasound
3
CA Breast
Aberrations in normal development and involution
PCOS
CA Cervix
Surgery
null
b7cc4806-cb5d-4a00-a4ca-75b265265fe0
single
Ototoxic drugs are all except
Ampicillin is penicillin. Remaining 3 are aminoglycoside. Aminoglycosides are ototoxic.Other adverse effects of aminoglycosides are nephrotoxicity and NMB.ototocicity can be of auditory and vestibular most vestibulotocxic is sterptomycin followed by gentamycin and most auditory toxic is neomycin followed by amikacin Re...
4
Kanamycin
Streptomycin
Gentamicin
Ampicillin
Pharmacology
Other topics and Adverse effects
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multi
Not a feature of diabetes mellitus in pregnancy
Neonatal complications Respiratory distress syndrome Hypoglycemia Polycythemia Hyperbilirubinemia Hyperviscosity Cardiomyopathy Bih trauma Reference: Textbook of Obstetrics; Sheila Balakrishnan, 2nd edition; Page no: 241
3
Postdatism
Hydramnios
Neonatal hyperglycemia
congenital defect
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
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single
A19 year old boy suffering from chronic schizophrenia is put on haloperidol in the dose of 20 mg/day. A week after the initiation of medication the patient shows restlessness, fidgety, irritability and cannot sit still at one place. The most appropriate treatment strategy is -
Ans: C Akathasia is the complication. It's the most common extrapyramidal side effect to develop due to use of antipsychotics. it appears within hoursto weeks of starting anti psychotics. Doc is propranolol.
3
Increase in the dose of haloperidol
Addition of anticholinergic drug
Addtion of beta blocker
Adding another antipsychotic drug
Psychiatry
Pharmacotherapy Management of Children and Adolescents
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Evidence based therapy of Bell's palsy include(s):
Answer- C. Steroid1. Medical treatmentPrednisolone (steroid) is the drug of choice and is staed at initial visit. Initiation of therapy during first 24 hours of symptom confers a higher likelihood of recovery.Antiviral therapy (Acyclovir) is a newer adjunct in treating acute facial palsy of viral origin (both Bell's pa...
3
Facial nerve massage
Facial nerve stimulation
Steroid
Acyclovir
ENT
null
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single
Which of the following is not a feature of Minimal change disease?
Ans. is 'a' i.e., Hypertension Minimal change disease (lipoid nephrosis)* Minimal Change Disease is the most common cause of Nephrotic syndrome in children.* Edema and Selective proteinuria are features of nephrotic syndrome. Fever may be present on account of increased susceptibility to infection.* Minimal change dise...
1
Hypertension
Edema
Proteinuria
Responsive to steroid therapy
Pediatrics
Kidney
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single
All are deep nuclei of cerebellum except-
Ans. is 'd' i.e., Caudate nuclei Important facts about cerebellumo Cerebellum is divided into -i) Cerebellar Cortex (external):- Contains five cellspurkinje cells, granule cells, basket cells, stellate cells and golgi cells.ii) Deep cerebellar nuclei (external):- There are four nuclei dentate fastigial, globose, and em...
4
Dentate nuclei
Emboliform nuclei
Fastigial nuclei
Caudate nuclei
Physiology
Cerebellum and Brainstem
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multi
All are true about Entamoeba Histolytica except -a) Cyst are 8 nucleatedb) Cyst are 4 nucleatedc) Trophozoites colonise in the colond) The chromatid bodies are stained by Iodides
Cyst of E. histolytical is quadrinucleate (4 nuclei) Chromatid bodies do not stain with iodine but are seen as refractile oblong bars with rounded ends in preprations with normal saline and as black when stained with iron-haematoxylin. Trophozoites colonize cecum and ascending colon, sigmoid colon, rectum and appendi...
4
b
c
ac
ad
Microbiology
null
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multi
True about lupus vulgaris – a) Apple jelly nodule at root of noseb) TB of skin & mucosac) Also known as scrofulodermad) ATT is helpful
Lupus vulgaris is the most common form of cutaneous (skin and mucosa) tuberculosis. Blanching with glass slide reveals grey green foci → Apple jelly nodules. Treatment is anti-tubercular drugs.
1
abd
bcd
abc
ab
Dental
null
b44f58c6-778a-4151-8428-861173f20e6b
multi
The intrinsic factor of the castle is secreted by which of the following cells in gastric glands
Secretions of stomach -        HCl- Parietal cells/ Oxyntic cells -        The intrinsic factor of Castle- Parietal cells/ Oxyntic cells -        Pepsinogen- Chief cells/ Peptic cells -        Gastrin- G cells -        Somatostatin- D cells -        Histamine- ECL cells
2
Chief cells
Parietal cells
Enterochromaffin cells
B cells
Physiology
null
30c19d4b-e9df-4e14-8042-20cde472edb9
single
Which anaesthetic is contraindicated in renal failure?
Ans. is 'd' i.e., Methoxyflurne Methoxyflurane It was most potent inhalation agent (least MAC), but not used not (now Halothane is most potent). o It should not be used in closed circuit (reacts with rubber tubing of the losed circuit). It has slowest onset & recovery (however now ether has slowest onset & recovery as ...
4
Isoflurane
Desflurane
Halothane
Methoxyflurne
Anaesthesia
null
392035ee-0139-4c6e-adea-e4497e6a152f
single
The aerial blood supply to the palatine tonsil is derived from branches of the external carotid aery. The principal aery is the tonsillar aery, which is a branch of the?
Facial Aery
1
Facial aery
Lingual aery
Superficial temporal aery
Maxillary aery
Anatomy
null
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single
Which of the following is true of body iron stores?
IRON DEFICIENCY ANAEMIA Iron Metabolism The amount of iron obtained from the diet should replace the losses from the skin, bowel and genitourinary tract. These losses together are about 1 mg daily in an adult male or in a non-menstruating female, while in a menstruating woman there is an additional iron loss of 0.5-1 m...
1
Absorption is increased in iron deficiency and reduced in iron overload
Normally iron is stored as hemosiderin
Hepcidin increases iron absorption in iron overload
Transferrin is used as a storage form in iron overload
Pathology
miscellaneous
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multi
Anaesthetic of choice in asthma patients: March 2007
Ans. C: Ketamine Ketamine is classified as an NMDA (N-methyl-D-aspaate) receptor antagonist, and at high, fully anesthetic level doses, ketamine has also been found to bind to opioid (mu) receptors and sigma receptors. Like other drugs of this class such as tiletamine and phencyclidine (PCP), it induces a state referre...
3
Halothane
Thipentone
Ketamine
Feanyl
Anaesthesia
null
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single
Arsenic poisoning presents with symptoms mimicking
ARSENIC * Copper arsenite - sheele&;s green * Copper acetoarsenite - paris green * Permissible limits of arsenic in ground water - 0.05mg/L * The gastroenteric type of poisoning resembles cholera * Greatest quantity is seen in - liver * Red velvety appearance of mucosa of stomach * Most affected pa of the stomach - pyl...
1
Cholera
Dhatura poisoning
Barbiturates poisoniong
Morphine poisoning
Forensic Medicine
All India exam
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single
After rupture of tympanic membrane the hearing loss is -
null
1
10-40 dB
5-15 dB
20 dB
300 dB
ENT
null
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single
Regarding diagnostic tests for syphilis, true is all except
For population screening for syphilis, VDRL or RPR test is appropriate.
3
VDRL test is used for measurement of antibody titers to assess response to treatment.
FTA-ABS is used to confirm diagnosis in clinically suspected syphilis.
TP-PA test is appropriate for population screening for syphilis.
Fourfold decrease in titer is required by 6 months after therapy for primary syphilis.
Gynaecology & Obstetrics
null
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multi
Psoralane Ultra Violet A (PUVA) therapy is advised in
According to Rook and Colleagues the extra corporeal photochernotherapy for drug resistant pemphigus vulgaris include administration of 8-methoxypsoralen followed by exposure of peripheral blood to ultraviolet radiation. It is also used for vitiligo and graft versus host disease.
1
Pemphigus vulgaris
Apthous ulcers
Carcinoma in situ
ANUG
Pathology
null
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single
A 5-year-old girl presents with difficulty breathing. On examination, of the oral cavity a 3 cm mass is found in the midline on the posterior aspect of the tongue. The most likely diagnosis is:
An ectopic thyroid gland can be located anywhere from the base of the tongue to the mediastinum. It often results in the failure of descent resulting in either a linginal thyroid or ectopic thyroid in the midline of the neck. The so called lateral aberrant thyroid is usually a metastasis from papillary carcinoma of the...
2
Lingual tonsil
Lingual thyroid
Foreign body stuck to the tongue
Dermoid
Surgery
Neck
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single
In those mammals which are seasonal breeder, the females are receptive only once in a year ; the cycle is termed as :
Ans. is b i.e. Estrous Estrous : It is cyclical period of sexual activity in non human female mammals, marked by congestion of and secretion by the uterine mucosa, proliferation of vaginal epithelium, swelling of the vulva, ovulation, and acceptance of the male by the female. During estrus, the animal is said to be "in...
2
Follicular
Estrous
Menstrual
Luteal
Gynaecology & Obstetrics
null
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single
Acetazolamide can be used in all except :
null
3
Epilepsy
Acute mountain sickness
Cirrhosis
Glaucoma
Pharmacology
null
bf734184-9689-495b-bcab-05bc108f0052
multi
Joint between epiphysis and diaphysis of a long bone is a type of:
Epiphysio-diaphyseal joint is a primary cartilaginous joint – synchondrosis. It is found in the growing bone, where the growth plate (hyaline cartilage) connects the epiphysis with the diaphysis, creating a hyaline cartilaginous joint. At this site the fate of synchondrosis is synostosis (bony fusion) after the growth ...
4
Plane Synovial joint
Fibrous joint
Symphysis
Synchondrosis
Anatomy
null
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single
Main inspiratory muscle is -
Ans. is 'd' i.e., Diaphragm Respiratory musclesInspiratory muscles1. During quiet breathing : Diaphragm (most important), external intercostal and interchondral part of internal intercostal.2. During forced inspiration : Sternocleidomastoid, serratus anterior, serratus posterior superior, pectoral is major and minor, e...
4
Lattissimus dorsi
Transversus thoracis
Serratus anterior
Diaphragm
Anatomy
Thorax
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single
All are true about bulimia nervosa, except
Bulimia NervosaBulimia nervosa is an eating disorder characterised by the following clinical features:1. Bulimia nervosa usually has an onset in early teens or adolescence.2. There is an intense fear of becoming obese. There may be an earlier history of anorexia nervosa.3. There is usually body-image disturbance and th...
3
Binge eating
Self-induced vomiting
Weight loss
Purgative abuse
Psychiatry
Sleep disorders and eating disorders
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multi
Kim et al classification system deals with:
According to Kim et al Classification; there are 5 types Type I incomplete isthmus between 2 canals. Type II well defined, complete isthmus between 2 canals. Type III very short but complete isthmus between 2 canals. Type IV 3 or more canals with the complete or incomplete isthmus. Type V 3 or more canals without any ...
3
Apical constriction
Apical foramen
Isthmus
No. of canals
Dental
null
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single
A child presents with recurrent bouts of severe cough followed by an audible whoop. Which of the following is considered the best type of specimen to isolate the organism and confirm the diagnosis
Peussis is an acute highly contagious respiratory tract infection caused by Bordetella peussis. Extremely contagious and clinical presentation can be divided into 3 stages like catarrhal, paroxysmal and convalescent It is called whooping cough due to the characteristic whoop produced by the air rushing in during inspir...
1
Nasopharyngeal swab
Cough plate
Throat Swabs
Anterior Nasal Swab
Pediatrics
Infectious disease
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single
Ion exchange chromatography is based on -
Ans. is 'b' i.e.. Charge Property of protein usedMethodProtein solubility'Salting out' or salt extraction (precipitation of protein by ammonium sulfate)Molecular sizeo Gel filtration chromatography (molecular-sieve chromatography or size exclusion chromatography)o Ultracentrifugationo SDS-PAGE (Sodium dodecvl sulphate-...
2
Size
Charge
Solubility
Polarity
Biochemistry
Miscellaneous (Structure & Function of Proteins)
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single
All of the following are useful in the management of acute asthma except :
null
3
Hydrocortisone intravenously
Salbutamol inhalation
Salmeterol inhalation
Terbutaline inhalation
Pharmacology
null
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multi
All of the following GIT hormones belong to secretin family except
Cholecystokinin (CCK) is secreted by cells in the mucosa of the upper small intestine. It has a plethora of actions in the gastrointestinal system, but the most impoant appears to be the stimulation of pancreatic enzyme secretion, the contraction of the gallbladder (the action for which it was named), and relaxation of...
3
Secretin
Glucagon
CCK
VIP
Physiology
G.I.T
1fe3ced3-7f19-4382-a515-a185f9f46027
multi
All are hepatotoxic drugs Except :
null
4
Erythromycin estolate
Rifampicin
Tetracycline
None
Pharmacology
null
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multi
Earliest sensation to be lost Hansens disease is -
In Hansen&;s disease ,the earliest sensation to be affected is usually light touch. Reference; Park&;s Textbook of preventive and social medicine, 24th edition.Pg no. 332
2
Pain
Touch
Vibration
Temperature
Social & Preventive Medicine
Communicable diseases
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single
Most common site of intracranial hemorrhage in hepeensive hemorrhage is :
Basal ganglia The most common sites of hypeensive haemorrhage are: The basal ganglia (putamen, thalamus and adjacent deep white matter) Deep cerebellum Pons
1
Basal ganglia
Brain.stem
Cerebellum
Hippocampus
Surgery
null
7b85ca57-6236-430b-915c-2955e089b6bb
single
Which mutation is seen in Down’s syndrome -
The basic molecular defect in Down's syndrome is the extra genetic material of chromosome 21. It may be due to : 1) Trisomy 21 This is the most common cause (95%). There is an extra chromosome 21 (i.e. three 21 chromosomes) which is due to meiotic nondisjunction in the ovum. The extra chromosome is of maternal origin...
2
Monosomy X
Trisomy 21
Trisomy 22
Trisomy 22
Pediatrics
null
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single
Testicualr tumor with best prognosis is :
null
2
Teratoma
Seminoma
Choriocarcinoma
All of the above
Surgery
null
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multi
Trochanteric fracture of the femur is best treated by -
Dynamic hip screw (DHS) plate is the implant of choice for fixation. These days proximal femoral nail (PFN) is also commonly used.
1
Dynamic hip screw
Inlay plates
Plaster in abduction
Plaster in abduction and internal rotation
Orthopaedics
null
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single
Destructive power of bullet is determined by all except
Ans. is 'c' i.e., Shape of bullet * Tissue damage (or destructive power of bullet) is dependent on striking (kinetic) energy of bullet, which is proportional to its mass and square of velocity (KE = Vi mv2). So modern bullets are designed to have smaller mass allowing transportation of large amount of ammunition and hi...
3
Velocity of bullet
Weight of bullet
Shape of bullet
Kinetic energy
Forensic Medicine
Injuries
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multi
Essential amino acid is:
Phenylalanine It is an alpha-amino acid. This essential amino acid is classified as nonpolar because of the hydrophobic nature of the benzyl side chain. L-Phenylalanine (LPA) is an electrically neutral amino acid The codons for L-phenylalanine are UUU and UUC. Phenylalanine is a precursor for tyrosine, the monoamine si...
1
Phenylalanine
Proline
Glutamine
Serine
Biochemistry
null
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single
Savlon contains :
Savlon is a very popular disinfectant in the hospitals and it contains chlorhexidine and cetrimide.
2
Cetrimide and cetavlon
Cetrimide and Chlorhexidine
Cetrimide, Chlorhexidine and butyl alcohol
Cetrimide and butyl alcohol
Pharmacology
null
b6f2d72c-3f76-446f-92c5-87fae48a677d
single
Which of the following condition is associated with a loss of attenuation reflex?
In stapedial palsy, damage to the nerve result in a reduction in sound attenuation reflex resulting in sound being heard excessively loud in the affected ear (hyperacusis). Attenuation reflex: When very loud sound is transmitted through the ossicular system to CNS a reflex is initiated with a latent period of 40 to 80m...
1
Stapedial palsy
Glomus tumor
Internal ear pathology
Malingerers
ENT
null
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single
In a patient with chronic atrial fibrillation with a regular beat of 60/min, the most probable cause is-
The health care provider may hear a fast heabeat while listening to your hea with a stethoscope. Your pulse may feel fast, uneven, or both. The normal hea rate is 60 to 100 beats per minute. In atrial fibrillation or flutter, the hea rate may be 100 to 175 beats per minute Digoxin toxicity is a life-threatening conditi...
2
Sleep
Digitalis toxicity
Sino nodal block
Hypothyroidism
Medicine
C.V.S
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single
2nd constriction of esophagus is due to -
Ans. is 'b' i.e., Arch of arorta Esophageal constrictionsNumberDistance from incisorBony levelAnatomical landmark1st2nd3rd4th15 cm (6 inches)22-5 cm (9 inches)27-5 cm (11 inches)37 -5 -40 cm (15-16 inches)C6T4T6T10At its beginning (pharyngoesophageal junction)Crossing of aortic archCrossing of left main bronchusPiercin...
2
Left principal bronchus
Arch of arorta
Pharyngoesophageal junction
None
Anatomy
Thoracic Duct & Esophagus
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multi
A person identifies a pattern on wall as an animal is having:
Ans: c) IllusionIllusion:Misinterpretation of stimuli arising from an external object. There are three types:i) Complete illusion: depends on inattention of the person. For eg: misreading words in newspapers / missing misprints, we read the word automatically as if it were complete. It also depends on our previous expe...
3
Hallucination
Delusion
Illusion
Sensory distortion
Psychiatry
Symptoms & Signs
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multi
True about caput succedaneum is -
Ans. is 'd' i.e., All of the above * A caput succedaneum is an edema of the scalp at the neonate's presenting part of the head. It often appears over the vertex of the newborn's head as a result of pressure against the mother's cervix during labor. The edema in caput succedaneum crosses the suture lines 8c its always p...
4
Crosses the suture lines
Always present at birth
Resolves in 24-48 hours
All of the above
Gynaecology & Obstetrics
Miscellaneous (Gynae)
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multi
What is the uppermost intercostals space used for hepatic biopsy -
Proper identification of the biopsy site is of paramount impoance. To choose the site, sta with percussion over the right upper quadrant. The biopsy site is usually located in the seventh or eighth intercostal space in the midaxillary line. The site can be fuher confirmed with either routine ultrasonography or a bedsid...
1
7th
10th
5th
9th
Medicine
G.I.T
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single
Anti-inflammatory drug that can safely be used in children is
Ans. b (Ibuprofen). (Ref. KDT 6th/pg. 191)AnalgesicPropertiesNimesulideDue to gastrointestinal, dermatological, renal & fulminant hepatic failure side effects, its safety, especially in children is questional. Banned in USA.IbuprofenSafest conventional NSAID.But should not be prescribed to pregnant women & peptic ulcer...
2
Paracetamol
Ibuprofen
Diclofenac
Nimesulide
Pharmacology
Miscellaneous (Pharmacology)
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single
Keloid scars:
null
2
Usually occur in the Caucasian race
Often occur in wounds which have healed perfectly without complications
Surgical treatment as a single modality has the least recurrence
Radiation should not be administered as it is a non¬malignant condition
Surgery
null
55a4e602-2837-48e3-bc02-11540ff9d155
multi
Exclusive breastfeeding is advised till what age?
Exclusive breastfeeding advised for 4-6months of age.(Refer: OP Ghai's Textbook of Pediatrics, 8th edition, pg no. 60, 122)
2
3 months
6 months
9 months
10 months
Pediatrics
All India exam
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single
Which is true about Burkitt's lymphoma?
Forms of Burkitt lymphoma: Sporadic and endemic Sporadic type: Presents in the abdomen near the ileocecal valve, in the ovaries, or in the retroperitoneum; 15-20% of sporadic-type Burkitt lymphomas are associated with EBV infection. Endemic type: Commonly presents in the jaw. All endemic-type Burkitt lymphomas are asso...
4
CD34 +ve & surface Immunoglobulin +ve
CD34 +ve & surface Immunoglobulin -ve
CD34 -ve & surface Immunoglobulin -ve
CD34 -ve & surface Immunoglobulin +ve
Pathology
null
a72e5417-a383-436e-b652-f504052c925c
multi
The characteristic of the pulmonary circulation:
Pulmonary aery pressures are reflective of RV pressures .Pulmonary circulation is low pressure, low resistance circulation as compared to systemic circulation. Pulmonary vessels are about 24 times more compliant compared to their systemic counterpas. Pulmonary circulation, in a sho route, has to accommodate large quant...
4
High resistance, high compliance
Low resistance, low compliance
High resistance, low compliance
Low resistance, high compliance
Physiology
Respiratory System
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single
Roopa Devi, a 65-year-old female with lymph-node-positive breast cancer was treated with systemic chemotherapy. Four weeks later, she developed frequent urination, suprapubic pain, dysuria, and hematuria. Which of the following could have prevented this patient's condition?
(Ref: Katzung 11/e p942) The patient described in the question has henorrhagic cystitiws caus3d by drugs like cyclophosphamide and ifosfamide. Hemorrhagic cystitis during therapy with cyclophosphamide or ifosfamide is caused by the urinary excretion of the toxic metabolite acrolein. This can be preventede by aggressive...
2
Folinic acid
Mesns
Dexrazoxane
Amifostine
Pharmacology
Other topics and Adverse effects
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single
A patient made a self-diagnosis of athlete's foot (tinea pedis) and began using a product adveised on television. The condition improved but did not clear and then the patient showed himself to a Dermatologist. A skin scraping was sent to the laboratory for culture, including culture for fungi. The fungal culture yield...
Ans. is 'a' i.e., Trichophyton . Dermatophytes can be identified by their colonial appearance and microscopic morphology after growth for 2 weeks at 25degc on sabouraud's dextrose agar. . Differential diagnosis of Dermatophytes on the basis of Macroconidia and microconidia General Microconidia Macroconidia Trichophyton...
2
Trichophyton
Microsporum
Epidermophyton
Trichosporon
Microbiology
null
fd7a96fe-1436-4ebd-a66f-d6524a81dc95
multi
Cerebral amaebiasis is not caused by:
Ans. c. Dientamoeba
3
Naegleria
Dientamoeba
Acanthamoeba
Balamuthia
Microbiology
null
ab4aecea-2371-41f6-9413-08b83e0a4783
single
Sensory nerve supply of middle ear cavity is provided by:
(b) Glossopharyngeal(Ref. Scott Brown, 8th ed., Vol 2 page 535)The sensory supply of the middle ear is by the tympanic plexus which is formed by the Jacobson's nerve which is the tympanic branch of Glossopharyngeal (IX) along with sympathetic plexus from around the internal carotid.
2
Facial
Glossopharyngeal
Vagus
Trigeminal
ENT
Ear
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single
All are features seen in Chronic Pancreatitis except ?
Ans. is 'd' i.e., Paralytic ileus
4
Chronic persistent pain
Diarrhoea, Steatorrhoea
Calcification
Paralytic ileus
Surgery
null
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multi
Best indication foe testicular biopsy in male is:
Testicular Biopsy in Male Infeility The testis biopsy provides direct information regarding the state of spermatogenesis Abnomalities of seminiferous tubules architecture and cellular composition are then categorized into several patterns. This procedure is most useful in the azoospermia patient, in which it is often d...
4
Polyspermia
Oligospermia
Necrospermia
Azoospermia
Surgery
Urology
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single
All of the following are sexually transmitted, Except –
Echinococcus granulosus (Hydatid disease) is not a STD. All other three options are STDs.
2
Candida albicans
Echinococcus
Molluscum contagiosum
Group B streptococcus
Dental
null
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multi
A 78-year-old man with a history of coronary aery disease and an asymptomatic reducible inguinal hernia requests an elective hernia repair. Which of the following would be a valid reason for delaying the proposed surgery?
The work of Goldman and others has served to identify risk factors for perioperative myocardial infarction. The highest likelihood is associated with recent myocardial infarction: the more recent the event, the higher the risk up to 6 months. It should be noted, however, that the risk never returns to normal. A non-Q-w...
3
Coronary aery bypass surgery 3 months earlier
A history of cigarette smoking
Jugular venous distension
Hypeension
Anaesthesia
Preoperative assessment and monitoring in anaesthesia
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single
Among the following, which one is not good dietary source of iron -
Haem iron is present in liver, meat, poultry, and fish. Non haem iron is present in green leafy vegetable,jaggery and dry fruit. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 623
4
Liver
Jaggery
Fish
Milk
Social & Preventive Medicine
Nutrition and health
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single
The fold in collagen is because of presence of:
The fold in collagen is because of presence of Glycine. ADDITIONAL READING ON STRUCTURE OF COLLAGEN: Collagen is made up of 3 alpha- chains (not alpha helix). These 3 chains together make a superhelix --> Tropocollagen(a rope like triple helix) Superhelix (right handed) is oured by Glycine residues. Glycine has the sma...
2
Histidine
Glycine
Argininc
Glutamate
Biochemistry
Glycine Metabolism Detail
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single
The unique propey of SERMs is that they:
SERM: 1. Raloxifene- Agonist at bone - Agonist in blood : Increase HDL level- Antagonist at breast: Decrease breast carcinoma risk- Antagonist at endometrium: Decrease endometrium carcinoma- Agonist at liver: Increase thromboembolism risk 2. Tamoxifen- Agonist at bone - Agonist in blood : Increase HDL level- Antagonist...
4
Have both estrogenic and progestational agonistic activity
Inhibits the aromatase enzyme that is required for estrogen synthesis
Produces estrogenic effect without binding to estrogen receptors
Act as agonist in some tissues and antagonist in other tissues
Pharmacology
Osteoporosis, Sex Hormones and OCPs
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multi
The common organism isolated in Emphysematous pyeloneohritis is
Emphysematous pyelonephritis (EPN) is a severe, necrotizing infection of the renal parenchyma causing gas formation within the collecting system, renal parenchyma, and/or perirenal tissues. Also called renal emphysema and pneumonephritis. Gas in the renal pelvis alone, without parenchymal gas, is often referred to as e...
1
E. Coli
Proteus
Pseudomonas
Klebsiella
Surgery
Urology
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single
A patient presents with a platelet count of 700 x 109/L with abnormalities in size, shape and granularity of platelets. WBC count of 12 x 109 /L, hemoglobin of 11g/dl and the absence of the Philadelphia chromosome. The most likely diagnosis would be-
null
2
Polycythemia vera
Essential thrombocythemia
Chronic myeloid leukemia
Leukemoid reaction
Pathology
null
49a16e93-7129-4023-9356-c09c0831118f
single
Which of the following is the most commonly used site for Transcranial Magnetic Stimulation to reduce frequency of Parkinsonism symptoms:
Answer is C (Subthalamic Nucleus): Primary Targets Subthalamic Nucleus (STN) Globus Pallidus Internus (GPI) Subthalamic Nucleus (STN) is the single most common preferred site for Deep Brain Stimulation in patients with Parkinsonism. Globus Pallidus Internus (GPi) is the second most common site for Deep Brain Stimulatio...
3
Striatus
Globus Pallidus
Subthalamic Nucleus
Putamen
Medicine
null
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multi
Renal plasma flow is increased by 50-75% during pregnancy. Which of the following is normally seen in the urine of a pregnant woman in the third trimester?
During pregnancy, renal threshold is diminished due to the combined effect of increased glomerular filtration and impaired tubular reabsorption of glucose. Also know: During pregnancy, renal tubules also fail to reabsorb uric acid, amino acids, water soluble vitamins and other substances completely. Glycosuria on one o...
1
Glucose
Galactose
Fructose
Sucrose
Gynaecology & Obstetrics
null
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multi
Post transcriptional modification include all except:
Glycosylation is a post translational modification, not a post transcriptional modification. Post Translational Modifications Post Transcriptional Modifications Phosphorylation Capping at 5'end Glycosylation (most frequent) Removal of Introns/ Splicing Hydroxylation Tailing at 3'end Acetylation Vit K Dependent Carboxyl...
4
5' capping
3' polyadenylation
Splicing
Glycosylation
Biochemistry
Transcription
ab75d591-7c8c-48c8-b7f8-2207c230e5d6
multi
Kaposi sarcoma is seen in -
null
3
Leukemia
Lymphoma
AIDS
Cytomegalovirus infections
Surgery
null
b2141e6c-2386-4906-b069-c5fe6fbfd5a6
single
Oxalate crytals in urine is seen in -
Oxalate crystals in urine is seen with Ethylene Glycol poisoning. Renal pain and acute tubular necrosis in it, occurs due to renal calcium oxalate precipitation. Other features includes, opthalmoplegia, cranial nerve palsies, hyporeflexia and myoclonus Reference: Harrison20th edition pg pg 789
1
Ethylene glycol poison
Di glycol poison
Alcohol
Indivavir
Medicine
Toxicology
4b439229-a9ed-481f-9889-5e5715e8a707
single
An HIV positive patient is pregnant. During which of the following stage is HIV transmission maximum?
Majority of HIV transmission occur during labour (40-80%). Perinatal transmission of HIV: Veical transmission of HIV to the neonate is about 14 - 25%. Transmission of HIV 2 is less frequent (1-4%) than HIV 1(14-35%). Veical transmission of HIV is more in cases with preterm bih and with prolonged membrane rupture. Risk ...
1
Labour
Early pregnancy
Late pregnancy
Post delivery
Gynaecology & Obstetrics
null
355df8ca-ea7e-4834-b7fc-6372c73a7830
single
Porin present in-
Ans. is 'd' i.e.. Outer membrane of gram negative bacteria o Cell envelop of bacteria comprises-An outer membrane (only in gram negative bacteria).A cell wall composed of peptidoglycan.Periplasm (only in gram negative bacteria).Cell membrane (cytoplasmic membrane), wrhich encloses cytoplasm.o Outer membranes, which are...
4
Cell wall of gram positive bacteria
Cell membrane of gram positive bacteria
Cell wall of gram negative bacteria
Outer membrane of gram negative bacteria
Microbiology
General
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multi
M in 99Tc"' stands for?
Metastable REF: Nuclear Physics: Principles And Applications by Lilley Page 20 "In 99Tcm the superscript M denotes that the technetium 99 is not in its ground state but a long lived metastable excited state"
3
Micro
Mega
Metastable
Metastatic
Radiology
null
fad29693-a438-4461-8ed8-a62ed18bc338
single
In MI, which enzyme is raised in 4 to 6 hrs and decreases in 3 to 6 days -
Ans. is 'c' i.e., CPKCreatinine phosphokinase (CK) Previously It was the gold standard marker of acute Ml.o But now it has largely been replaced by troponin T and I (see above explanation).o But, CK remains the best alternative to troponin measurement.CK-MB isotype of this enzyme is specific for myocardium.It is raised...
3
SGOT
LDH
CPK
SGOT
Pathology
null
3db37ca6-c82d-4fd2-b0a5-6d7efcc659cc
single
Which of the following statements in not true regarding Lac Operon concept
Lac operon is regulatory method seen only in prokaryotes.
2
CAP is a positive regulator of LAC operon
It is regulation method in eukaryotes and prokaryotes
It is inducible operon
Lac Z gene codes for β galactosidase.
Biochemistry
null
a5c19009-dbf7-449d-9b85-939da7ccac97
multi
During treatment for Wilson disease with trientine and penicillamine, free serum copper should be kept below which level?
The normal free copper value is 10-15 mcg/dL and it is often as high as 50 mcg/dL in untreated Wilson's disease. With treatment, free copper should be <25 mcg/dL. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 3190
1
25 mcg/dl
50 mcg/dl
75 mcg/dl
100 mcg/dl
Medicine
null
baa471b1-7296-45c4-b051-43443803fc78
single
Psammoma bodies shows which type of calcification -
Ans. is 'b' i.e., Dystrophic
2
Metastatic
Dystrophic
Secondary
Any of the above
Pathology
null
1dcc7baa-98e2-4dc9-9dfb-d28aa95e03b6
multi
The order of sensory blockade of local anesthesia is:
Individual type of nerve differs in their minimal blocking concentration. Not all sensory and motor modalities are blocked equally by local anesthetics. This is termed differential blockade. For different fibers order of blockade b > AS = C > AU > A b > Aa autonomic > sensory> motor is the sequence of block. for sensor...
1
Temperature - pain - touch - pressure
Pain - pressure - touch - temperature
Touch - pressure - temperature - pain
Touch - pain - pressure - temperature
Anaesthesia
Regional Anesthesia
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single