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72d687b1-942c-421b-9ba3-e6bc9312161e
Cleft lip is due to non-union of
Maxillary process with MNP
MNP - LNP
MNP - MNP
All of the above
0
multi
null
Surgery
null
4bfec2de-e6e7-41c6-bbe9-3dc864f9d719
Sickle cell anemia is a -
Gene deletion
Gene modification
Point mutation
Frame shift mutation
2
single
Answer- c- point mutation.Sickle-cell anemia is caused by a point mutation in the b-globin chain of hemoglobin, causing the hydrophilic amino acid glutamic acid to be replaced with the hydrophobic amino acid valine at the sixth position.It is caused by a point mutation (Base substitution mutation) at the sixth position of the b-globin chain leading to subsitution of a valine residue for a glutamic acid residue resulting in sickle hemoglobin (HbS).Sickle cell anemia is an autosomal recessive disorder.
Biochemistry
null
a18a805c-102a-4493-9a14-9fef1f17862f
All are true about widal test except
Base lines differ depending on the endemicity of the disease
O antibodies last longer and hence is not indicative of recent infection
H antigen cannot differentiate between subtypes
High titre value in a single widal test is not confirmative
1
multi
null
Microbiology
null
cb8ad6b2-009b-443e-9237-85b46e3a87a5
What is the name of the given instrument, used for harvesting the graft from healthy area in split thickness skin graft?
Dermatome
Silver's knife
Catlin amputating knife
Humby knife
3
single
Humby Knife A knife with a roller attached, used for cutting skin grafts of varying thickness The distance between the roller and blade of knife can be varied by means of a calibration device.
Surgery
AIIMS 2018
56176afa-3442-46be-9cdc-c8e569a72d04
A person working in an abattoir presented with a papule on hand, which turned in to an ulcer. Which will best help in diagnosis
Polychrome Methylene blue
Carbol Fuschin
Acid Fast Stain
Calcoflour White
0
single
null
Microbiology
null
6e9406e3-faad-4e92-b1e5-3b21190db3d8
A midwife at a PHC did per vaginal examination of a women in labor with 8 cm cervical dilation and 70% cervical effacement with the fetal head at +1 station. This +1 station implies the position of fetal head is-
1 cm above the ischial spine
1 cm below the ischial spine
At the level of ischial spine
1 cm below the cervical os
1
multi
Answer-B. 1 cm below the ischial spineStation describes descent of the fetal biparietal diameter in relation to a line drawn between maternal ischial spines. Thus+1 station implies fetal head is 1 cm below the ischial spine.
Gynaecology & Obstetrics
null
7a4da866-2f41-4510-aa28-0dabdf6d0d38
High content of cholesterol is present in:
Coconut oil
Egg yolk
Hydrogenated fat
Ghee (unsaturated)
1
single
null
Biochemistry
null
24a53b0f-d1b7-4ef8-8b9c-1d3b857aa413
Tooth with smallest root
Mandibular central incisor
Mandibular lateral incisor
Maxillary lateral incisor
Maxillary 1st premolar
0
multi
null
Dental
null
7ddf1f3b-5c7c-4f2d-b208-f01ea72e1a70
The function of a sprue is to
Form an opening for molten metal to enter the mold
Help polish cast restorations
Eliminate air bubbles on the wax pattern
Reproduce fine detail
0
single
null
Dental
null
d8178128-49db-4790-aa08-7c49e8e7ad5f
Access cavity of mandibular 1st molar is:
Oval
Rounded triangle
Rhomboid
None of the above
1
multi
1st choice for access cavity preparation in mandibular 1st molar is trapezoidal. 2nd choice is rounded triangle.
Dental
null
e9f104f9-2231-4a49-b5a6-983ca6e08c49
A pier abutment is:
Periodontally weak abutment
With an edentulous space on mesial and distal sides of the abutment
Edentulous space on one side of the abutment
Abutment adjacent to edentulous space
1
multi
null
Dental
null
2902efec-b01a-417c-94b9-406e94662f27
According to the new RNTCP guidelines, the following is not a suspect of tuberculosis
Confirmed extra-pulmonary tuberculosis patient with cough of 2 weeks or more
HIV-positive patient with cough of any duration
Contacts of sputum positive tuberculosis patient with cough of any duration
Any individual having cough of duration 2 weeks or more
0
single
Ans: A. Confirmed extra-pulmonary tuberculosis patient with cough of 2 weeks or more(Ref: Park 24/e p188-189, 23/e p178: 22/e p 168; htip://tbcindia.nic.in)A contact of confirmed extra-pulmonary tuberculosis patient - TB suspect.If persistent cough of any duration (2 weeks is not required).TB suspects:Pulmonary TB Suspect:Defined as:Any individual having cough of >2 weeks.Contacts of smear positive TB patients having cough of any duration.Suspected/confirmed extra-pulmonary TB patient having cough of any duration.HIV-positive patient having cough of any duration.MDR-TB Suspect:Any TB patient who fails an RNTCP Category failing I or III treatment regimen.Any RNTCP Category II patient with sputum smear positive at end of 4th month of treatment or later.Close contacts of MDR-TB patients with smear positive pulmonary TB.
Social & Preventive Medicine
null
6d426ea7-e119-4b5f-be99-1e36084c332c
All are topical hemostatic agents except?
Bone wax & patty
HemCon bandage
Quikclot
Fixclot
3
multi
Ans. D. Fixclot Topical hemostatic agents are used when surgical hemostasis is inadequate or impractical. The majority of routine, elective operations are performed in patients with normal hemostasis and with minimal blood loss.The two main categories of topical hemostatic agents are physical agents, which promote hemostasis using a passive substrate, and biologically active agents, which enhance coagulation at the bleeding site
Pharmacology
null
e21be124-85de-4313-bc26-ff82218fce73
Which of the following pulp horn of primary molar is commonly exposed during restorative procedures:
Mesiobuccal puplhorn of 1st molars.
Distobuccal pulp horn of 1st molars.
Mesiobuccal pulp horn of 2nd molars.
Distobuccal pulp horn of 2nd molars.
0
single
The mesiobuccal pulphorn of permanent maxillary 1st molar is commonly exposed during cavity preparation. Mesiolingual pulphorn of permanent mandibular 1st molar is commonly exposed during cavity preparation. Mesiobuccal pulphorn of primary 1st molars is commonly exposed during restorative procedures on primary molars.
Dental
null
70069985-3660-4a24-b55c-c689592bc9a3
Rate of Dentinal fluid permeability depends on all except?
Temperature variation
Pressure gradient across dentinal tubule
Increase viscosity of dentinal fluid
Rate of removal of substances by blood vessels
0
multi
null
Dental
null
45d2b684-c55a-400b-ab09-76ee3a9ba64b
Extraction of disto-angular impaction of mandibular 3rd molar can cause:
Slippage in lingual pouch
# of ramus of mandible
Excessive Haemorrhage
Dry socket
1
single
null
Surgery
null
1b18ac4d-8101-48f1-bcc9-b53391c550ab
Acetazolamide is given to a patient of angle closure glaucoma. It is a non- competitive inhibitor of carbonic anhydrase enzyme. Which of the following should be the effect of this drug?
Decrease in Vmax
Decrease in Km
Decrease in both Km and Vmax
No change in Vmax
0
multi
Enzyme inhibition is of 3 types: Type of inhibition Km Vmax Competitive inhibition Increases No change Non competitive inhibition No change Decreases Uncompetitive inhibition Decreases Decreases In question non competitive inhibitor is given, so answer is decrease in Vmax.
Pharmacology
AIIMS 2018
535bf03d-8714-46a8-84a0-13bf499129f7
Which of the following does not require 5'capping?
tRNA of alanine
mRNA for histone
U6 snRNA
siRNA
0
single
Ans: A. tRNA of alanineSmall nuclear RNAs contain a unique 5'-caps. Sm-class snRNAs are found with 5'-trimethylguanosine caps, while Lsm-class snRNAs are found with S'-monomethyl phosphate caps.mRNAs do have a 7-methylguanylate cap, abbreted m7G.tRNAs and rRNAs don't require 5' capping. They have other modifications.
Biochemistry
null
965fa6a2-969e-4b51-bdb7-934a02c809f6
Peau d'orange in carcinoma breast is due to:
Obstruction of sub-dermal lymphatics
Infiltration of Cooper's ligament
Hematogenous dissemination
Hematogenous dissemination
0
single
Ans: A. Obstruction of sub-dermal lymphaticsPeau-d-orange is due to cutaneous lymphatic edema.Caused by obstruction of subdermal lymphatics. As the disease advances locally there may be skin involvement with peau d'orange or frank ulceration and fixation to the chest wall. This is described as cancer-en-cuirasse when the disease progresses around the chest wall.
Surgery
null
90c2699f-da32-4a4a-ade8-afc27e0cba3e
True about adult polycystic kidney disease is all, except:
Autosomal dominant inheritance
Hypertension is rare
Can be associated with cysts in liver, lungs and pancreas
Pyelonephritis is common
1
multi
Hypertension is common in patients with autosomal dominant polycystic kidney disease. It is present in 75% of adult patients and 25% of children.
Pathology
null
59ade17d-2139-4c4b-b0b5-ec6d6cf3c073
Propranolol is drug of choice for -
Ulcerated infantile hemangioma
Lymphangioma
Pyogenic granuloma
Capillary malformation
0
single
Ans. A. Ulcerated infantile hemangiomaRef: <a href=" hemangiomas (IHs) are the most common benign pediatric soft-tissue tumors.</li>Ulceration--the most frequent complication of IH--tends to heal poorly and is associated with pain, bleeding, infection, and scarring.Mainstay treatment modalities include propranolol (b-blocker) and coicosteroids, whose effectiveness is countered by a need for long-term medication and risk of systemic adverse effects and ulcer recurrence.
Pharmacology
null
a28aea2d-6784-4a02-bd4c-90cb24e64c77
During pregnancy baby can be affected in utero in all except:
Candida
Syphilis
Toxoplasmosis
Polio
3
multi
In case of polio only feco-oral transmission is known, no placental transmission has been reported yet All other disease mentioned may be transmitted to fetus by mother I am in doubt about candida, because although congenital candidiasis can occur, the mode of transmission is not transplacental but ascending infection from external genitals of mother or during parturition. But as far as the answer is concerned it is undoubtedly “POLIO”.
Gynaecology & Obstetrics
null
8a85e4e4-e42b-41a9-87e2-6f8e7105262c
Long term assessment of glucose control can be made by:
Estimation of post prandial blood sugar
Estimation of fasting blood sugar
Estimation of urine sugar level
Estimation of blood level of glycosylated hemoglobin
3
single
null
Medicine
null
82e0c97f-b421-4836-a0ec-602fb1045910
Mosaic pattern of bone is seen in radiographic features of:
Fibrous dysplasia
Paget's disease
Osteopetrosis
Osteogenesis imperfecta
1
single
null
Pathology
null
a2a5e8a4-ab54-45c1-b50b-5cd81d4f5af8
Fourth generation meth-acrylate based resin sealer include?
Endorez
Resilon
Hydron
Real Seal E
3
single
null
Dental
null
e45de5c9-41f3-4aed-a77a-9a1cc3ee63db
Maternal moality ratio expressed in:-
Maternal death per 10,000 lives
Maternal death per 100,000 lives
Maternal death per 1,000,000 lives
Maternal death per 100 lives
1
single
null
Gynaecology & Obstetrics
AIIMS 2018
698d05f7-bd3d-4df6-a17f-e78e207ff835
Which induction anaesthetic agent has antiemetic effect?
etomidate
propofol
thiopentone
ketamine
1
single
null
Pharmacology
null
9a5e8865-e37c-41af-a902-1c10423dbdd4
A 10 year old boy following a road traffic accident presents to the casualty with contaminated wound over the left leg. He has received his com- plete primary immunization before preschool age and received a booster of DT at school entry age. All of following can be done except :
Injection of TT
Injection of human antiserum
Broad spectrum antibiotics
Wound debridement and cleaning
1
multi
null
Microbiology
null
148f5ca1-0e61-4e4a-a19a-47df89cb1689
In Myocardial infarction, the major pathology is
Ischemia caused by dynamic obstruction of a coronary artery.
Myocardial necrosis caused by acute occlusion of a coronary artery.
Ischemia due to fixed atheromatous stenosis of one or more coronal artery.
Altered conduction due to ischemia or infarction.
1
single
null
Medicine
null
dee8c0a8-bcc0-4f67-815f-4a7b1c0963bc
Localized Juvenile Periodontitis- primary pathogen is
Acinobacillus Actinomycetemcomitans
Prevotella intermedia
Mycoplasma
all the above
3
multi
null
Dental
null
8b42e1df-196b-4d7a-bbd7-39fe76dee239
A male child with Fanconi syndrome with nephrocalcinosis has a variant of dent disease. All are true except :
Hypercalciuria
Proteinuria
Similar presentation in father
Rickets
2
multi
Dent's disease : Dent's disease, a familial proximal tubular syndrome, is an X-linked recessive disorder of proximal tubules characterized by : Hypercalciuria and nephrocalcinosis and nephrolithiasis. Low-molecular-weight proteinuria. Metabolic bone disease/Rickets. Progressive renal failure. Marked inale predominance. In addition to above features, other renal proximal tubular defect can cause: (i) Fanconi syndrome (Aminoaciduria, proteinuria, phosphaturia). (i) Glycosuria, uricosuria and kalliuresis. (iii) Impaired urinary acidification. Dent's disease occurs due to mutations that inactivate a voltage-gated chloride transporter, CLC-.5. In some cases, it is associated with mutations in the OCRL-1 gene that is also mutated in the oculocerebral syndrome of Lowe. Coming back to question. Dent's disease is an X-linked renal tubular disorder. X-linked disease cannot be transmitted from male to male i.e., from father to son.
Pediatrics
null
46f87e87-5b3e-465d-ae94-bd65b5f333c2
Which of the following is not involved in blood clotting?
Calcium
Prothrombin
Fibrinogen
Fe+2
3
single
null
Physiology
null
e62b12e5-0a92-44d3-95b0-33bbf59bd891
DNA Methylation is not related with?
Mismatch repair
DNA Replication
Gene silencing
Capping
3
single
Capping of mRNA in eukaryotes: 7-Methyl Guanosine cap is added at the 5' end of mRNA by enzyme Guanylyl Transferase. So, this is RNA methylation, not DNA. DNA methylation Epigenetic mechanism Transfer of methyl group to C5 position of cytosine to form 5-methyl cytosine. DNA replication Dnmt (DNA methyl transferases) during DNA replication to copy DNA methylation pattern from parental strand to daughter strand Mismatch repair -Identify parent strand with help of CH3
Biochemistry
AIIMS 2020
2ef6a0de-c83f-461e-93c9-88f38320bf5e
While preparing a Class II cavity on a maxillary first molar which of the pulp horns are likely to get exposed:
Mesiolingual and mesiobuccal
Distolingual and distobuccal
Mesiolingual and distobuccal
Distolingual and mesiobuccal
0
single
null
Dental
null
d3629a0f-c519-46c6-bb27-a33adc0ac0fc
Additional period required for enamel calcification after eruption into oral cavity
1 yr
2 yr
3 yr
4 yr
1
single
null
Dental
null
8b72fc76-d0bf-4cd2-b7dc-05d030560c52
All are Gp lIbilIla inhibitors except:
Prasugrel
Abciximab
Tirofiban
Eptifibatide
0
multi
Ans: A. Prasugrel(Ref Goodman Gilman 13/e p595, 12/e p870; Katzung 13/e p595, 12Ie p612; KDT 7/e p631)Prasugrel reduce platelet aggregation by inhibiting the ADP pathway of platelets. It irreversibly blocks the ADP receptor on platelets.Targets for platelet inhibitory drugs:Inhibition of prostaglandin synthesis (aspirin).Inhibition of ADP- induced platelet aggregation (clopidogrel, prasugrel, ticlopidine).Blockade of glycoprotein Ilb/IIIa receptors on platelets (abciximab, tirofiban, and eptifibatide). Dipyridamole & cilostazol - Additional antiplatelet drugs.
Pharmacology
null
044e8f11-ca21-4220-9ddc-0fca648ed401
The active principle of white oleander is:
Nicotine
Nerin
Abrine
Pilocarpine
1
single
Ans. b. NerinNerium odorum (white oleander, kanero) grows wild in India.. Seed pod is slim, cylindrical, ribbed, up to l5 cm. long, tums brown, dries and splits, releasing small seeds tipped withbrown hair.. All pas of the plant including nectar are poisonousq.. It contains several cardiac glycosides, primarily:- Oleandrosidee (Oleandrin) and Nerioside (Nerin), both of which resembles digitalis in action- Folinerin- Rosagenin
Forensic Medicine
null
743b8121-1201-4592-a552-25cad3198d07
The yellowish white soft sticky deposit loosely adherent present on tooth surface is
Materia alba
Food debris
Plaque
Calculus
0
single
null
Dental
null
55093e71-8916-4f25-9524-9425d51455e1
A term gestation newborn developed respiratory distress. Which of the following would favour Respiratory distress syndrome (HIVID) ?
History of receiving antenatal corticosteroids
Air bronchogram on chest x–ray
Onset of distress after 6 hours of birth
Term birth
1
single
chest x-ray of an infant with RDS is characterized by atelectasis, air bronchograms, and a diffuse reticular-granular pattern commonly referred to as "ground glass". The chest x-ray may progress to a complete "white out" with severe disease. About other options Antenatal corticosteroids are given in pre-term (pre-mature) pregnancies not in term pregnancies. Further, antenatal corticosteroids are given to prevent RDS (HMD) --> after antenatal corticosteroids administration, risk of HMD is reduced. Respiratory distress occurs within first 6 hours. HMD occurs in pre-term neonate.
Pediatrics
null
4d39dabb-c57f-4a2d-a979-fd4347773e76
‘Fleur -de- lys’ term is used for:
Dens invaginatus
Denticle
Odontome
Supernumerary tooth
0
single
null
Pathology
null
80066b5e-d621-4912-b7fd-f1e867a9c8d4
Renal feed for CKD patients-
Low calorie low volume
Low calorie high volume
High calorie low volume
High calorie high volume
2
single
Answer- C. High calorie low volumeLimiting fluids, eating a low-protein diet, limiting salt, potassium, phosphorous, and other electrolytes, and getting enough calories if you are losing weight.
Medicine
null
34f8fb1a-a365-40d0-a804-6b061a9a04f5
Point used as termination of Root canal procedure is
Apical constriction
Apical foramen
Both
None
0
multi
null
Dental
null
3c667386-1965-43cd-bbf5-5c573cd2403b
Kwashiorkar , true is
Deficiency of protein with sufficient calorie intake
Occurs in children between 6 months and 3 years of age
Subcutaneous fat preserved but atrophy of different tissues
All of the above
3
multi
null
Biochemistry
null
a9dccfec-0882-4012-aa1b-e74bb18bf47e
Lenolin is added in ZOE paste to:
Decrease flow
Increase flow
Accelerate reaction
Decrease irritation due to eugenol
1
single
null
Dental
null
8a8401da-6bcd-46d5-bf27-72371291311e
Which of the following is not transmitted by lice
Q fever
Trench fever
Relapsing fever
Epidemic typhus
0
single
null
Dental
null
b9d0ecb7-910b-4740-a744-5e7fa0780a3e
What will be the oxygen carrying capacity of an 18-year-old patient with a hemoglobin of 14 g/dL?
7
14
18
28
2
single
Answer- C. 18Each gram of hemoglobin can bind with a maximum of 1.34 milliliters of oxygen (1.39 milliliters when the hemoglobin is chemically pure, but impurities such as methemoglobin reduce this).Here, Hb = 14.Hence, oxygen carrying capacity: l.34 x 14 = 18 mLO2/dL
Physiology
null
2ede6af0-7501-44aa-aa19-39afbe3cf71f
All the following muscles of larynx are supplied by the recurrent laryngeal nerve except:
Cricohyoid
Cricothyroid
Arytenoid
Aryepiglotticus
1
multi
null
Anatomy
null
179b5138-d8ce-4e02-9445-ada73b642671
Which of the following techniques is based on RNA?
PCR
Sanger's technique
Next generation sequencing
Western blot
0
single
Ans: A. PCRReverse transcription-polymerase chain reaction (-PCR) It is a laboratory technique combining reverse transcription of RNA into DNA (in this context called complementary DNA or cDNA) and amplification of specific DNA targets using polymerase chain reaction (PCR).It is primarily used to measure the amount of a specific RNA. This is achieved by monitoring the amplification reaction using fluorescence, a technique called real-time PCR or quantitative PCR (qPCR). Combined -PCR and qPCR are routinely used for the analysis of gene expression and quantification of viral RNA in research and clinical settings.A method used to quantitate mRNA levels that rely upon the first step of cDNA copying of mRNAs catalyzed by reverse transcriptase before PCR amplification and quantitation. Sanger sequencing,Also known as the chain termination method, is a technique for DNA sequencing-based upon the selective incorporation of chain-terminating dideoxynucleotides (ddNTPs) by DNA polymerase during in vitro DNA replication.Next-generation sequencing:Modified methods of genome sequencing. It has significantly reduced the cost and time taken for whole-genome sequencing.It is a technique similar to Sanger sequencing, done on DNA
Biochemistry
null
c70d078e-2a95-4779-b8d5-6050a5b58394
Minimum concentration of oxygen needed in NO analgesia
10%
20%
30%
40%
2
single
null
Pharmacology
null
d2dd3a90-bed4-4897-ab87-50fef0041b29
In rheumatoid arthritis there is inflammation of:
Cartilage
Synovial membrane
Sclerosis of joints
Articular bone
1
single
null
Medicine
null
991ff4a7-4adc-4136-854d-b6c007d5d1be
Winged rubber dam retainer in endodontics advantages are all except
Radiographs are good showing full length of canals
Stability
Provide extra bucco-lingual retraction
Dam, clamp and frame placed in one operation
0
multi
null
Dental
null
da80560b-dc14-4a57-ba81-cee414172692
A 11-year-old child comes to the dental office one hour after injury to a maxillary central incisor. The tooth is vital and slightly mobile. Radiographic examination reveals a fracture at the apical third of the root. What is the best treatment at this point of time:
Render palliative therapy
Extract the tooth
Relieve the occlusion and splint the tooth
Perform immediate root canal treatment and splint
2
multi
null
Dental
null
76e1d3a2-90b6-4735-be99-004263456619
Resistance form of endodontics is:
Resists movement of gutta-percha in apical area
To allow use of spreader in lateral condensation
Fracture of root while vertical condensation
None of the above
0
multi
null
Dental
null
a7e312f2-177e-4acf-9ac9-f68f6cb484ea
Antibody in chronic allergy ?
IgM
IgA
IgG
IgE
3
multi
Answer- D- IgEWhen someone has allergies, their immune system makes an antibody called immunoglobulin E (IgE). These antibodies respond to allergens. The symptoms that result are an allergic reaction.IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic uicaria and atopic dermatitis.
Microbiology
null
45ea4d89-40f7-42af-8f94-b4dc1e9a5466
While assessing the efficacy of a newly developed drug in comparison to placebo, the 95% confidence interval in clinical trials is used to check for:
Efficacy of the drug
Non-efficacy of the drug
Both efficacy and non-efficacy of the drug
Either efficacy or non-efficacy of the drug
0
multi
Answer- a (efficacy of the drug)
Pharmacology
null
9ce14fee-cf4f-4066-b94f-361bd7165049
Which material is the most difficult to remove from the patient's mouth?
Metallic oxide paste
Silicone impression material
Reversible hydrocolloid
Impression plaster
0
multi
In dentistry, zinc oxide eugenol is popular as an impression material for making impressions of edentulous arches for the construction of complete dentures. It is classified as a rigid, irreversible impression material. It cannot be used for recording impressions of dentate arches and in areas of severe undercuts. Mannapalli ed 3 page no 166
Dental
null
206f23c8-9973-48b9-9f26-2601d4d61e25
Main cause of RPD failure is:
Improper clasp design
Insufficient contact of teeth
Insufficient contact of teeth and improper clasp design
None of the above
2
multi
null
Dental
null
ad195e5d-7f52-42cc-a183-b05e3181d0ab
A 40 years old female presented with acute onset shoness of breath. She has a history of nephrotic syndrome 1 year back and recent prolonged air travel. She has a BP of 90/60 mm Hg, hea rate of 115 per minute and sinus tachycardia on ECG. A 2-D echocardiogram revealed dilation of right ventricle with bulging of the interventricular septum to the left. What will be the primary treatment modality?
Thrombectomy
Intravenous tissue plasminogen activator
Unfractionated heparin
d. IVC filter
1
single
Ans: B. Intravenous tissue plasminogen activator (Ref: Harrison 19/e p1634-1636, 18/2170-2177)Findings indicate patient most probably suffering from massive pulmonary embolism.Management of Massive Pulmonary Embolism:For patients with massive PE & hypotension, replete volume with 500 mL of normal saline.Additional fluid should be infused with extreme caution-Due to excessive fluid administration exacerbates RV wall stress a more profound RV ischemia & worsens LV compliance and filling.Dopamine & dobutamine - 1st line inotropic agents for PE-related shock treatment.Fibrinolysis in Massive Pulmonary Embolism:Preferred fibrinolytic regimen: Recombinant tissue plasminogen activator (tPA).Contraindications: Intracranial disease, recent surgery & trauma.
Medicine
null
2b1e65d8-098f-4bf9-9511-aa5f87b0af89
In multirooted teeth, formation of multiple roots is due to presence of:
Epithelial diaphragm
Cell rests of Malassez
Toot bud division or bell stage
None of the above
0
multi
Prior to beginning of root formation, the HERS forms epithelial diaphragm. The outer and the inner enamel epithelia bend at the future cementoenamel junction into a horizontal plane, narrowing the wide cervical opening of the tooth germ. Differential growth of the epithelial diaphragm in the multi rooted teeth causes the root trunk into two or three roots.
Dental
null
1163160d-9432-4143-98af-ef59704fc876
In Down syndrome patient, which teeth have severe periodontitis
Lower Anterior
Upper Anterior
Upper Molar
Lower Molar
0
single
null
Dental
null
c8f62b0d-908c-494c-9ccf-90297f3647a6
Folic acid deficiency occurs in:
Aspirin
Phenytoin
Chloromphenicol
Cyclosporine
1
single
null
Pharmacology
null
93d8bac0-76ae-4440-91c0-fa3b724bbc65
Which of the following will not decrease mother to child transmission of HIV?
Avoid breastfeeding
Vaginal delivery
Zidovudine given to mother antenataly and to neonate after bih
Vitamin A supplementation given to mother
1
single
Answer- B (Vaginal delievery)Vaginal delivery increases risk of mother to childhood transmission of HIV.'HIV can be transmitted through breast milk, avoiding breast feeding decreases the mother to child transmission of HIV.'
Gynaecology & Obstetrics
null
73dc80de-280f-4ee5-bc41-b1843e16a16d
On the day following a formocresol pulpotomy of a mandibular molar, a three year old patient returned with a large ulcer near the midline of the lower lip. What is the probable cause of the ulcer?
Lip biting by the patient
Allergy to the anaesthetic solution
Pressure by the rubber dam frame
Leakage of formocresol on the lip
0
multi
null
Dental
null
ee343e97-60cc-402d-8c90-c92e8f168813
Which of the following conditions is associated with polyhy dramnios?
Posterior urethral valve
Cleft palate
Congenital diaphragmatic hernia
Bladder exostrophy
1
single
null
Gynaecology & Obstetrics
null
0f2fc319-7fca-4f39-b2e9-be49e7abe79d
Chemotactic cytokine is
IL-1
IL-6
IL-8
TNF
2
single
null
Microbiology
null
4c0b406e-5d78-4f1d-99ca-c51f8d240e4f
A 38 years old female presented to the emergency with extensive burns. The patient had grade 3 burns on the face, back, upper arms and forearms along with singeing of hairs. Which of the following is not a proof of inhalation burns?
Yellow colored sputum
Blackish soot deposit on posterior pa of tongue
Hoarseness & stridor of voice
Singeing of eyebrows and facial hair
0
single
Ans: A. Yellow colored sputum(Ref Reddy 33/e p325-326: Parikh 6/e p4. /60)Yellow sputum/ phlegm = Mostly a sign of bacterial infection.In burns takes time to develop.Grade 3 burns:Sputum with carbonaceous colored.Singeing of facial hair, burns on face, soot marks & singed eyebrows or facial hair - Indicative of acute burns inhalational injury.Features of inhalation injury:Characteristic:History of fire in an enclosed space.Burns of face.Singed nasal & facial hair.Inflamed pharyngeal mucosa.Carbonaceous sputum.Evidence of edematous glottis (e.g., hoarseness).
Forensic Medicine
null
27e5fe55-e6b8-49eb-b141-78c1e4fd1e14
After spleenectomy patient becomes more prone to
Gram +ve & anaerobic
Gram -ve & anaerobic
Nonencapsulated
Encapsulated organisms
3
multi
null
Surgery
null
c6f28135-76b7-4762-bd13-839b1592e3d3
All of the following are developed from Meckel's cartilage except:
Zygomatic bone
Malleus
Incus
Stapes
3
multi
null
Anatomy
null
864ebcb5-85f5-45eb-a209-5d14ef53e787
In judicial hanging, the knot is placed at:
Below the chin
Angle of the jaw
The back of the neck
Choice of hangman
1
single
Ans: B. Angle of the jawJudicial Hanging:Placement of knot beneath the chin (submental position) - Most effective.Ensures quicker death.In India & UK, left sub-aural (below the angle of the jaw) knot - Preferred for hanging.Process:The rope is looped around the neck & person is allowed to drop for 5-7 meters - According to weight, age & build of the person.A sudden stop causes fracture-dislocation usually at the level of C2-C3 or C3-C4 veebra & rupture of brain stem between pons & medulla.Death is instantaneous.Hea-beat may continue for 15-20 minutes & spasmodic muscle jerking may occur for a considerable time.
Forensic Medicine
null
cda9b8dd-1c5b-4b7d-b08c-8e959ab72415
Non-pulsatile dose of GnRH agonist is used in all the following conditions except-
Endometriosis
infeility
Precocious pubey
Prostate cancer
1
multi
Ans.B.Male infeilityGnRH is used in all those conditions where there is increased estrogen as GnRH decrease estrogen secretion.Mnemonic :* A - F and HIP* A = Adenomyosis* B = Irritable Bowel Syndrome (under Trial)* C = Ca Breast (Tamoxifen + GnRH agonist give good result)* D = DUB* E = Endometriosis* F = Fibromyoma uterus.* H = Hirsutism* I = Infeility* P = Precocious Pubey.
Gynaecology & Obstetrics
null
21ee5793-fb33-407c-81ba-7f01f5eefe47
Eisenmenger syndrome–True are A/E –
Pulmonary veins are not distended
RV & LV walls come back to normal size
Dilatation of central pulmonary artery
Peripheral pruning of pulmonary arteries
1
multi
The characteristic pathological pulmonary vascular changes that develop in a patients with Eisenmenger syndrome are confined to arteries only and involve small pulmonary arterioles and muscular arteries (veins are not involved). There is right ventricular hypertrophy (RV walls do not come back to normal size). On x-ray there are dilated and prominent central arteries with rapid tapering (pruning) of the peripheral vasculature.
Pediatrics
null
c850f730-17c6-4978-a37e-93796d1a0e9e
Gap healing, a type of primary healing having gap of 0.8 mm is healed as:
Direct lamellar bone formation.
Woven bone formation replaced by lamellar bone.
Woven bone formation only.
Any of the above.
1
multi
null
Surgery
null
7655a989-3ec8-4f83-a2ea-a1a2527d483e
The radiographic examination of a traumatized tooth is essential -
To establish baseline data
To find associated root fracture
To determine stage of root development
All of the above
3
multi
null
Dental
null
13088525-20c1-4b21-8fba-f48097969211
The fifth nerve innervates the following:
Mylohyoid, anterior and posterior belly of digastric
Mylohyoid, anterior belly of digastric, and tensor tympani
Mylohyoid, posterior belly of digastric and tensor tympani
Mylohyoid, posterior belly of digastric, Stapedius and tensor tympani
1
single
Trigeminal nerve is the 5th cranial nerve. It is a mixed nerve containing both the motor and sensory fibres but predominantly it is sensory. It is a motor nerve to the muscles of mastication and several small muscles and the principal sensory nerve of the head and face. It consists of three large nerves: ophthalmic, maxillary, and mandibular, hence the name trigeminal nerve (L. trigeminus = triplet). Key concept: Mandibular nerve supplies muscles of mastication mylohyoid, anterior belly of digastric, and tensor tympani. Posterior belly of digastric and stapedius are supplied by Facial nerve.
Anatomy
null
f5f3cd4b-3180-4f0e-b585-d681407b89d0
A study was conducted to find average intra-ocular pressure. IOP was measured in 400 people and the mean was found to be 25 mm Hg with a standard detion of 10 mm Hg. What is the range in which 10P of 95% of the population would be lying?
22-28 mm Hg
20-30 mm Hg
24-26 mm Hg
23-27 mm Hg
2
single
Ans: C. 24-26 mm HgStandard error, SE = {standard detion / n)}n = sample sizeC= Confidence coefficient = 1.96 for 95% confidence interval = 2.58 for 99% confidence interval= 3.29 for 99.9% confidence intervalHence in this question, n = 400SD = 10SE = 10/400 = 10/20 = 0.5Mean statistic = 25 mm Hg.Now for 95% confidence interval,C = 2 approximately 95%CI = 25 - 2x0.5 to 25 + 2x0.5 = 24-26 mm HgHence, 95% CI of IOP = 24 to 26 mm Hg.
Social & Preventive Medicine
null
c1e4be05-7faa-4d6a-9d3a-5c825129daaf
The lag phase of tooth movement usually lasts for:
2-3 mins
2-3 hrs
2-3 day
2-3 weeks
3
multi
null
Dental
null
48d70d58-19bb-4648-b72b-d49e9cbb0147
Which of the following is a common osseous lesion in periodontitis is
Exostosis
crater
buttressing bone
hemiseptum
1
single
null
Dental
null
e0952660-983f-4990-a8c6-d6b6bc19aca3
Which of the following groups of fibres are not attached to alveolar bone?
Transseptal
Horizontal
Oblique
Apical
0
single
null
Dental
null
8d8150e4-2224-4ac1-b41e-b8353a744dcc
First nerve fiber present in vicinity of dental papilla in
Bud stage
Cap stage
Bell stage
Advanced Bell stage
0
single
null
Dental
null
d2aaf9d3-3ec9-450c-94cd-7df423fe49e8
A 32 years old female came for routine PAP smear testing. The repo came as carcinoma in situ. What is the next step?
HPV-DNA testing
Hysterectomy
Conization
Colposcopy and biopsy
3
multi
Answer- D. Colposcopy and biopsyRegressions typically occur within a 2-year follow-up with cytology & colposcopy.Observation - Biopsy diagnoses of CIN 1 with satisfactory colposcopy and who agree to the evaluation every 6 monthsAblative treatment - lf the lesions progress during follow-up or persist at 2 yearsTreatment options: LEEP & Cryosurgery
Gynaecology & Obstetrics
null
f9e59986-dc69-42ca-97c9-593496bb98a5
The frontal paranasal sinus drains into the:
Superior meatus
Middle meatus
Inferior meatus
Spheno-ethmoidal recess
1
single
null
Anatomy
null
d5f7c86d-3441-4fdd-8618-8510dbead871
In the mammalian genome, maximum number of genes code for the receptors of:
Immunoglobulin receptors
Interleukins
Growth factors
Odorants
3
single
Ans: D. OdorantsIn the mammalian genome, maximum number of genes code for the receptors of odorants."The olfactory receptor (OR) genes constitute the largest gene family in mammalian genomes.Humans have >1,000 OR genes, of which only -40% have an intact coding region and are therefore putatively functional.Odorant receptor genes form the largest gene family in the genome of many animals: for example, the mouse genome contains approximately 1200 of these genes.
Biochemistry
null
b57b3bed-fda6-48e7-9af4-f72d5a4687d9
Pegloticase is used in
Chronic gout
Paralytic ileus
Psoriatic ahritis
Rheumatoid ahritis
0
single
Pegloticase - It is recombinant uricase, an enzyme which oxidises uric acid to highly soluble allantoin, that is easily excreted by kidney. Humans lack this enzyme. In this preparation, the enzyme has been coupled with methoxy polyethylene glycol (mPEG) which serves to prolong its sojourn in the body, permitting i.v. infusion of the drug to be given every 2 weeks. It is indicated only in rare cases of refractory symptomatic gout because it is immunogenic and carries high risk of infusion reactions, including anaphylaxis.
Pharmacology
AIIMS 2019
74d6497b-16bd-44f8-bba0-a9a139482e77
Wave patterns of EEF, ECG and EMG are depicted below. The B pattern belongs to (Figure was not provided in the exam):
NREM sleep
REM sleep
Wakefulness
Quiet wakefulness
2
single
Answer- C. WakefulnessBeta (B) Wave- Parietal and frontal region. Patients awake, at rest with eyes open.
Physiology
null
f4b8bacb-390e-4efa-9e65-f7f1bfe8b32b
Staphylococcus aureus and pneumoniae are responsible for:
Subacute endocarditis.
Acute endocarditis.
Post operative endocarditis.
None.
1
multi
null
Medicine
null
16ce8442-864b-43f1-b815-f9096e55fa54
First paranasal sinus to develop at bih is:
Maxillary
Ethmoidal
Frontal
Sphenoidal
0
single
Development of SinusesSinusGestational Month WhenDevelopment StasPresent in ClinicallySignificant SizeFully DevelopedMaxillary2degBihdeg12 yearsdegEthmoid30Bihdeg12 yearsdegFrontal4deg3 yearsdeg18-20 yearsdegSphenoid3deg8 yearsdeg12-15 yearsdeg
ENT
null
5c1652a1-905f-4be0-8677-4259eb94b2d0
Which of the following is the best test for assessment of intestinal malabsorption?
Fecal fat estimation
Serum lactose levels
Serum amylase levels
NBT-PABA test
0
single
Ans: A(Ref: Harrison 19/c p193(S)Fecal fat estimation - Gold standard test for diagnosis of malabsorption.Intestinal malabsorption diagnosis:D-xylose test.Tests for xylose absorption in intestinal villi.Distinguishs intestinal from pancreatic malabsorption.Pancreatic malabsorption diagnosis:NBT-PABA & serum amylase.
Medicine
null
611828ae-4acf-4177-bc88-fd78e72a9a3e
Primary Colonization of plaque is dominated by
Facultative Aerobic Gram + ve rods
Facultative Anaerobic Gram - ve rods
Facultative Aerobic Gram - ve cocci
Facultative Anaerobic Gram + ve cocci
3
single
null
Dental
null
83935f21-0298-409f-aabc-ac42dc4c0e00
Types of pocket respectively:
Simple pocket, compound pocket, complex pocket.
Simple pocket, complex pocket, compound pocket.
Compound pocket, simple pocket, complex pocket.
Simple pocket, compound pocket, tertiary pocket.
0
single
null
Dental
null
d053ff7a-d056-4da2-b124-68610654796f
Depression of mandible is achieved by:
Digastric
Lateral pterygoid
Geniohyoid
All of the above
3
multi
null
Dental
null
18d1c316-555c-4528-a9c4-e8ce1a613179
18 year old female presents with an ovarian mass, her serum bio marker are found to be normal except for LDH, which is found to be elevated. The most likely diagnosis is:
Dysgerminoma
Endodermal sinus tumor
Malignant terratoma
Mucinous cystadeno carcinoma
0
multi
NOTE :- * Young girls with - Germ cell tumor Ovarian mass * Old women with - Epithelial serous tumor Ovarian mass Biomarkers Dysgerminoma | LDH, | placental alkaline Po4 Endodermal sinus tumor a feto protein and antitrypsin
Gynaecology & Obstetrics
AIIMS 2017
4c74361f-7de5-4a70-9221-c8f5c9554081
Most common infection post solid organ transplantation
CMV
HSV
EBV
HPV
0
single
Cytomegalovirus (CMV) is transmitted post solid organ transplantation whereas herpes simplex virus (HSV) is transmitted post solid organ transplantation only within a month. Epstein-Barr virus (EBV) is a glandular disease so transmitted by close contact where as human papilloma virus (HPV) is transmitted through sexual contact since it is a sexually transmitted disease. So first option is a better option. Infection in Children: Primary infections in older children and adults are usually asymptomatic. However, a heterophile, antibody-negative, infectious mononucleosis may been. This is more common following transfusion of CMV-infected blood (post - transfusion mononucleosis).
Microbiology
AIIMS 2019
3b38f235-0a3f-4781-ae19-a7858523b39f
Tuberculous otitis media is characterized by all except -
Multiple perforations
Pale granulations
Pain
Thin odourless fluid
2
multi
Tubercular Otitis Media Important points: ––Seen mainly in children and young adult Q ––It is secondary to pulmonary tuberculosis. Q ––Route of spread - Mainly through eustachian tube (not blood borne). Q Symptoms: 1. Patients often present with chronic painless otorrhoea (usually foul smelling) which is resistant to antibiotic treatment Q 3. Severe conductive type hearing loss Q. (sometimes due to involvement of labyrinth may be SNHL) 4. Facial nerve palsy may be the presenting symptom in childrenQ 5. Cough; fever and night sweats may be present in patients with tuberculous infection in other organ system. O/E –– Multiple perforationsQ in tympanic membrane (This feature was once considered characteristic of TB but now is seldom seen). –– Middle ear and mastoid are filled with pale granulation tissueQ (It is a characteristic of tuberculous otitis media) Complications: (Early onset of these symptoms is seen) ––Mastoiditis ––Osteomyelitis ––Postauricular fistula ––Facial nerve palsy
ENT
null
b0d97337-7157-40c6-984d-87e24959fa80
Child Pugh score put patients into three categories of Score A (<7), Score B (7-9) and Score C (10-15). The following is a type of which scale?
Nominal
Ordinal
Quantitative
Continuous
1
single
Child Pugh Score' divides the scores into 3 CATEGORIES, hence it is a CATEGORICAL scale. The variables are qualitative and arranged in an order of increasing severity, hence it is an example of ORDINAL scale. Other options: Nominal scale is also a type of categorical scale in which the variables are not arranged in any order. Metric scale is used for quantitative variables. Continuous is a type of variable and not a type of scale.
Social & Preventive Medicine
AIIMS 2017
1c8618e4-c3cc-4048-8214-8c3098ba12ad
Skin of the entire upper lip is supplied by:
Maxillary nerve.
Facial nerve.
Mandibular nerve.
None.
0
multi
null
Anatomy
null
e18f0c87-2d93-4fb1-9b7f-41ddc4ea0cae
Microangiopathic hemolytic anemia
TTP
ITP
Senile purpura
CML
1
single
null
Medicine
null
1f93c541-baaf-40f2-bf91-31be29732da2
Treatment of choice for anaphylactic shock is:
Adrenaline 0.5 mL of 1:1000 solution by intramuscular route
Adrenaline 1 mL of 1:10000 by intravenous route
Atropine 3 mg intravenously
Adenosine 12 mg intravenously
0
single
DOC is adrenaline.Route is intramuscular > subcutaneous.Dose: 0.5 ml of 1:1000(1mg/ml solution).This dose is repeated once gain within 10 minutes.If it's still not improving; then intravenous 1:10,000 dose is given.
Pharmacology
AIIMS 2017
565d9d77-689a-4e68-bd65-7016980692ba
The cotton applied to the pulpal stumps in the formocresol pulpotomy technique should be
Slightly dampened with formocresol
Saturated with formocresol
Left for 2 hours in the cavity
Sealed until the next appointment.
0
single
null
Dental
null
4fbc569b-3b88-490f-b1b9-0af7c459eee0
Which of following is not a tumor suppressor gene?
pRb
FHIT
PTCH
c-erbB1
3
single
null
Pathology
null
c4c72573-bba7-4544-8e80-7bf4fe8d0f2d
All the following instruments are required for tonsillectomy except:
Coblation wand
Bipolar cautery
Microdebrider
Harmonic scalpel
2
multi
Ans: C. Microdebrider(Ref: Scott-Brown's 7Ie p3576; Cummings Pediatric Otolaryngology By Marci M. Lesperance, Paul W. Flint/p51; Dhingra 6/e p430)All these four instruments are used in different techniques of tonsillectomy.Microdebrider is less commonly used than others as it leaves behind a small amount of tissue covering theconstrictor muscle.Hence, preferred answer would be microdebrider.
ENT
null