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1,687 | Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na(+)/K(+) transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834214/
SHA: efbd0dfc426da5dd25ce29411d... | What are the main groups for Mammarenaviruses? | false | 5,150 | {
"text": [
"Old World (OW) and New World (NW)"
],
"answer_start": [
2898
]
} |
1,586 | In Vitro Bactericidal Activity of 4- and 5-Chloro-2-hydroxy-N-[1-oxo-1-(phenylamino)alkan-2-yl]benzamides against MRSA
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321674/
SHA: f0e6cef57dbae030aea2f324e21e00945ac659cf
Authors: Zadrazilova, Iveta; Pospisilova, Sarka; Pauk, Karel; Imramovsky, Ales; Vinsova, Jarmila; ... | What is the most common, clinically-relevant multiresistant pathogen in both healthcare and community acquired infections? | false | 5,226 | {
"text": [
"Methicillin-resistant Staphylococcus aureus (MRSA)"
],
"answer_start": [
1919
]
} |
1,596 | Glycyrrhizin Exerts Antioxidative Effects in H5N1 Influenza A Virus-Infected Cells and Inhibits Virus Replication and Pro-Inflammatory Gene Expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096629/
SHA: f3b7f4469ac01f1ce916d24172570c43c537627e
Authors: Michaelis, Martin; Geiler, Janina; Naczk, Patrizia; Sithi... | What is the conclusion of the study? | false | 5,241 | {
"text": [
"glycyrrhizin might also serve as lead structure for the development of novel anti-influenza drugs"
],
"answer_start": [
18948
]
} |
1,623 | Etiology of Influenza-Like Illnesses from Sentinel Network Practitioners in Réunion Island, 2011-2012
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031398/
SHA: f5ff89ebfdd0375d034c112c6c1c7e163fa69a0c
Authors: Brottet, Elise; Jaffar-Bandjee, Marie-Christine; Li-Pat-Yuen, Ghislaine; Filleul, Laurent
Date: 2016-09-21... | What tool has been developed to identify several viruses simultaneously? | false | 4,099 | {
"text": [
", multiplex reverse transcriptase polymerase chain reaction (RT-PCR)"
],
"answer_start": [
3806
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} |
1,671 | Host resilience to emerging coronaviruses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079962/
SHA: f7cfc37ea164f16393d7f4f3f2b32214dea1ded4
Authors: Jamieson, Amanda M
Date: 2016-07-01
DOI: 10.2217/fvl-2016-0060
License: cc-by
Abstract: Recently, two coronaviruses, severe acute respiratory syndrome coronavirus an... | What is the role of interferon's (IFNs) in the treatment of SARS-CoV? | false | 1,274 | {
"text": [
"there is some evidence that simultaneous treatment with IFNs could increase the potential benefits"
],
"answer_start": [
10624
]
} |
1,604 | Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243941/
SHA: f5b706d0529bfcf7e2d1dfc037df5b6f95fc5ec0
Authors: Sun, Bing; He, Hangyong; Wang, Zheng; Qu, Jiuxin; Li, Xuya... | What are the high resolution pulmonary CT scan findings for patients with severe cases of human adenovirus type 55 (HAdV-55)? | false | 3,250 | {
"text": [
"Consolidations within a single lobe or several lobes with a clear border and air bronchogram were the most common findings on HRCT scans. Nodules, patches, pleural effusion, abscess and a cavity were also seen visualized by HRCT"
],
"answer_start": [
10189
]
} |
2,683 | Estimating the number of infections and the impact of non-
pharmaceutical interventions on COVID-19 in 11 European countries
30 March 2020 Imperial College COVID-19 Response Team
Seth Flaxmani Swapnil Mishra*, Axel Gandy*, H JulietteT Unwin, Helen Coupland, Thomas A Mellan, Harrison
Zhu, Tresnia Berah, Jeffrey W Eato... | What is France's estimated mean percentage [95% credible interval] of total population infected as of 28th March? | false | 850 | {
"text": [
"3.0% [1.1%-7.4%]"
],
"answer_start": [
13164
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} |
2,684 | 1918 Influenza: the Mother of All Pandemics
Jeffery K. Taubenberger" and David M. Morens1-
The “Spanish" influenza pandemic of 1918—1919,
which caused :50 million deaths worldwide, remains an
ominous warning to public health. Many questions about its
origins, its unusual epidemiologic features, and the basis of
its p... | Could the 1918 swine flu virus been controlled by modern day drugs or vaccines? | false | 1,117 | {
"text": [
"the 1918 and 1918-like Viruses would be\nas sensitive as other typical Virus strains to the Food and\nDrug Administrationiapproved antiinfluenza drugs riman-\ntadine and oseltamivir."
],
"answer_start": [
27291
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} |
1,660 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Which proteins and mRNAs prominently induced by hantaviruses include? | false | 4,483 | {
"text": [
"hantaviruses have been identified as adversely affecting"
],
"answer_start": [
10002
]
} |
187 | Preparation for Possible Sustained Transmission of 2019 Novel Coronavirus
Lessons From Previous Epidemics
https://jamanetwork.com/journals/jama/fullarticle/2761285
February 11, 2020
David L. Swerdlow, MD1; Lyn Finelli, DrPH, MS2
Author Affiliations Article Information
JAMA. 2020;323(12):1129-1130. doi:10.1001/jama.2020... | What is the acronym MERS-CoV? | false | 248 | {
"text": [
"Middle East respiratory syndrome coronavirus"
],
"answer_start": [
722
]
} |
2,669 | Frontiers in antiviral therapy and immunotherapy
https://doi.org/10.1002/cti2.1115
SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf
Authors: Heaton, Steven M
Date: 2020
DOI: 10.1002/cti2.1115
License: cc-by
Abstract: nan
Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l... | How much have the number of biomedical research publications targeting 'translational' concepts has increased ? | false | 4,125 | {
"text": [
"exponentially, up 1800%"
],
"answer_start": [
842
]
} |
2,504 | Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052386/
SHA: 45a566c71056ba4faab425b4f7e9edee6320e4a4
Authors: Tan, Kai Sen; Lim, Rachel Liyu; Liu, Jing; Ong, Hsiao Hui; ... | What other viruses are implicated in acute exacerbations but to a much lesser extent? | false | 3,883 | {
"text": [
"parainfluenza virus (PIV), influenza virus (IFV) and adenovirus (AdV)"
],
"answer_start": [
6720
]
} |
1,741 | MERS coronavirus: diagnostics, epidemiology and transmission
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687373/
SHA: f6fcf1a99cbd073c5821d1c4ffa3f2c6daf8ae29
Authors: Mackay, Ian M.; Arden, Katherine E.
Date: 2015-12-22
DOI: 10.1186/s12985-015-0439-5
License: cc-by
Abstract: The first known cases of Middle East ... | Which are the preferred method for MERS-CoV detection? | false | 4,228 | {
"text": [
"PCR-based techniques"
],
"answer_start": [
12007
]
} |
1,671 | Host resilience to emerging coronaviruses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079962/
SHA: f7cfc37ea164f16393d7f4f3f2b32214dea1ded4
Authors: Jamieson, Amanda M
Date: 2016-07-01
DOI: 10.2217/fvl-2016-0060
License: cc-by
Abstract: Recently, two coronaviruses, severe acute respiratory syndrome coronavirus an... | How does transmission differ between SARS-CoV and MERS-CoV? | false | 1,268 | {
"text": [
"SARS-CoV also spreads more rapidly between hosts, while MERS-CoV has been more easily contained, but it is unclear if this is due to the affected patient populations and regions"
],
"answer_start": [
4750
]
} |
2,683 | Estimating the number of infections and the impact of non-
pharmaceutical interventions on COVID-19 in 11 European countries
30 March 2020 Imperial College COVID-19 Response Team
Seth Flaxmani Swapnil Mishra*, Axel Gandy*, H JulietteT Unwin, Helen Coupland, Thomas A Mellan, Harrison
Zhu, Tresnia Berah, Jeffrey W Eato... | As of the end of March what is the proportion of Spain's population to be infected? | false | 843 | {
"text": [
"15.0% (7.0 [18-19] million people)"
],
"answer_start": [
12685
]
} |
1,660 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What happens by the time that secondary viremia emerges? | false | 4,549 | {
"text": [
"the agents of the more severe forms of HFRS and HCPS have begun to achieve sufficient mass"
],
"answer_start": [
16586
]
} |
1,579 | Viral Respiratory Tract Infections in Adult Patients Attending Outpatient and Emergency Departments, Taiwan, 2012–2013: A PCR/Electrospray Ionization Mass Spectrometry Study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635751/
SHA: ef6361c7bffb9e92f397d7004bfb3a9c804d7c6a
Authors: Shih, Hsin-I; Wang, Hsuan-Chen; Su... | What was the purpose of this study? | false | 4,077 | {
"text": [
"to comprehensively investigate the viral epidemiology of adult RTIs"
],
"answer_start": [
850
]
} |
1,568 | Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/
SHA: f2e835d2cde5f42054dbd0c20d4060721135c518
Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi
Date: 2017-12-07
DOI: 10.1186/s13104-017-3063-1
License:... | What symptoms are associated with acute respiratory infections? | false | 1,602 | {
"text": [
"sore throat, fever, couch, running nose, vomiting, body ache, leg pain, nausea, chills, shortness of breath"
],
"answer_start": [
6502
]
} |
1,741 | MERS coronavirus: diagnostics, epidemiology and transmission
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687373/
SHA: f6fcf1a99cbd073c5821d1c4ffa3f2c6daf8ae29
Authors: Mackay, Ian M.; Arden, Katherine E.
Date: 2015-12-22
DOI: 10.1186/s12985-015-0439-5
License: cc-by
Abstract: The first known cases of Middle East ... | What is the basic reproduction number (R 0 ) for MERS-COV? | false | 4,299 | {
"text": [
"close to one"
],
"answer_start": [
47059
]
} |
1,689 | Chikungunya: A Potentially Emerging Epidemic?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860491/
SHA: f7c3160bef4169d29e2a8bdd79dd6e9056d4774c
Authors: Thiboutot, Michelle M.; Kannan, Senthil; Kawalekar, Omkar U.; Shedlock, Devon J.; Khan, Amir S.; Sarangan, Gopalsamy; Srikanth, Padma; Weiner, David B.; Muthumani... | What has the E1-A226V enabled? | false | 2,515 | {
"text": [
"an increase in infectivity of Ae. albopictus when compared to its infectivity of Ae. aegypti"
],
"answer_start": [
8761
]
} |
2,634 | Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067204/
SHA: c097a8a9a543d69c34f10e5c3fd78019e560026a
Authors: Chan, Jasper Fuk-Woo; Kok, Kin-Hang; Zhu, Zheng; Chu, Hin; To, Kelv... | What are the examples that have emerged as human pathogens? | false | 3,700 | {
"text": [
"severe acute respiratory syndrome CoV (SARS-CoV) which emerged in China in 2002-2003 to cause a large-scale epidemic with about 8000 infections and 800 deaths, and Middle East respiratory syndrome CoV (MERS-CoV) which has caused a persistent epidemic in the Arabian Peninsula since 2012"
],
"answe... |
1,686 | Nucleolar Protein Trafficking in Response to HIV-1 Tat: Rewiring the Nucleolus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499507/
SHA: efa871aeaf22cbd0ce30e8bd1cb3d1afff2a98f9
Authors: Jarboui, Mohamed Ali; Bidoia, Carlo; Woods, Elena; Roe, Barbara; Wynne, Kieran; Elia, Giuliano; Hall, William W.; Gautier, Virgin... | What types of cells are used to study Tat-mediated pathogenesis? | false | 5,146 | {
"text": [
"Jurkat T-cells"
],
"answer_start": [
32303
]
} |
1,698 | Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064339/
SHA: f2cc0d63ff2c4aaa127c4caae21d8f3a0067e3d5
Authors: Brook, Cara E; Boots, Mike; Chandran, Kartik; Dobson, Andrew P; Drosten, Christian; Graham, Andrea L; Grenfell, Bryan T; ... | What would be the benefit of learning more about bat's defenses and how they drive virus evolution? | false | 2,735 | {
"text": [
"help scientists develop better ways to predict, prevent or limit the spread of viruses from bats to humans."
],
"answer_start": [
6903
]
} |
1,674 | Beyond phage display: non-traditional applications of the filamentous bacteriophage as a vaccine carrier, therapeutic biologic, and bioconjugation scaffold
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523942/
SHA: f00f183d0bce0091a02349ec1eab44a76dad9bc4
Authors: Henry, Kevin A.; Arbabi-Ghahroudi, Mehdi; Scott, Jam... | What is the result of all species tests of phage particles? | false | 1,749 | {
"text": [
"is immunogenic without adjuvant in all species tested to date, including mice (Willis et al., 1993) , rats (Dente et al., 1994) , rabbits (de la Cruz et al., 1988) , guinea pigs (Frenkel et al., 2000; Kim et al., 2004) , fish (Coull et al., 1996; Xia et al., 2005) , non-human primates (Chen et al., 2... |
2,440 | Optimization Method for Forecasting Confirmed Cases of COVID-19 in China
https://doi.org/10.3390/jcm9030674
SHA: 1d7f8850c5244fdc9b387038e7eeae9bcbbde6d2
Authors: Al-Qaness, Mohammed A. A.; Ewees, Ahmed A.; Fan, Hong; Abd El Aziz, Mohamed
Date: 2020
DOI: 10.3390/jcm9030674
License: cc-by
Abstract: In December 2019,... | Where was the coronavirus discovered? | false | 4,393 | {
"text": [
"Wuhan, China"
],
"answer_start": [
377
]
} |
1,607 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | What is the third most prevalent cancer in females in the United States? | false | 5,278 | {
"text": [
"colorectal cancer"
],
"answer_start": [
2187
]
} |
1,603 | Genome Sequences of Porcine Epidemic Diarrhea Virus: In Vivo and In Vitro Phenotypes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056290/
SHA: f6d6d7efc1686a7d219ecfc55f9a48ce72d4fb00
Authors: Lawrence, Paulraj K.; Bumgardner, Eric; Bey, Russell F.; Stine, Douglas; Bumgarner, Roger E.
Date: 2014-06-12
DOI: 10.1128/... | What is the size of the PEDV genome? | false | 5,268 | {
"text": [
"26 to 32 kb"
],
"answer_start": [
1745
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} |
1,574 | Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907881/
SHA: ef821e34873d4752ecae41cd9dfc08a5e6db45e2
Authors: Hughes, Michelle M; Englund, Janet A; Kuypers, Jane; Tielsch, James M; Khatry, Subarna K; Shrestha, Laxman; LeClerq... | What is the WHO criteria for a pertussis infection? | false | 2,174 | {
"text": [
"a minimum of 2 weeks of cough, whoop, or posttussive vomiting"
],
"answer_start": [
17093
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} |
1,631 | Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 Expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300492/
SHA: f0c2cd2793d71f1ea11a810442a2c06d5013e899
Authors: Yu, Haijing; Liu, Yang; Wang, Hongwu; Wan, Xiaoyang; Huang, ... | What is fibrinogen-like protein 2 (FgI2)? | false | 5,292 | {
"text": [
"a pro-coagulant protein"
],
"answer_start": [
748
]
} |
1,656 | Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541410/
SHA: f2fcc16391f946c99717b63ec9a24e5384aac381
Authors: Zhu, Xiaojie; Zhu, Yun; Ye, Sheng; Wang, Qian; Xu, Wei; ... | What kind of model best describes the pharmacokinetic profiles of AP3 and AP2? | false | 2,261 | {
"text": [
"non-compartment model"
],
"answer_start": [
8522
]
} |
1,590 | In Vitro Antiviral Activity of Circular Triple Helix Forming Oligonucleotide RNA towards Feline Infectious Peritonitis Virus Replication
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950953/
SHA: f5ad2323eb387f6e271e2842bb2cc4a33504fde3
Authors: Choong, Oi Kuan; Mehrbod, Parvaneh; Tejo, Bimo Ario; Omar, Abdul Rahman... | What type of vaccine is used to protect against FIPV infection? | false | 4,055 | {
"text": [
"an attenuated, temperature-sensitive strain of type II FIPV"
],
"answer_start": [
2958
]
} |
1,604 | Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243941/
SHA: f5b706d0529bfcf7e2d1dfc037df5b6f95fc5ec0
Authors: Sun, Bing; He, Hangyong; Wang, Zheng; Qu, Jiuxin; Li, Xuya... | What is the mean rate of respiration upon admission to the ICU when admitted for human adenovirus type 55 (HAdV-55)? | false | 3,247 | {
"text": [
"43 breaths per minute"
],
"answer_start": [
9244
]
} |
188 | The Battle Against Coronavirus Disease 2019 (COVID-19): Emergency Management
and Infection Control in a Radiology Department
https://www.jacr.org/article/S1546-1440(20)30285-4/pdf
Journal Pre-proof
Zixing Huang, Shuang Zhao, Zhenlin Li, Weixia Chen, Lihong Zhao, Lipeng Deng, Bin
Song
PII: S1546-1440(20)30285-4
DOI: htt... | How was the contaminated area connected to the CT room and other facilities? | false | 2,450 | {
"text": [
"connected to the fever clinic and\nincludes the fever accessway, the CT examination room, and the DR examination room for\n6\nconfirmed and suspected cases. One CT scanner and one DR system closest to the emergency\ndepartment are designated the fever-CT and fever-DR to examine patients with suspecte... |
1,571 | Community-acquired pneumonia in children — a changing spectrum of disease
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608782/
SHA: eecb946b106a94f26a79a964f0160e8e16f79f42
Authors: le Roux, David M.; Zar, Heather J.
Date: 2017-09-21
DOI: 10.1007/s00247-017-3827-8
License: cc-by
Abstract: Pneumonia remains the lea... | How has the number of childhood pneumonia been reduced? | false | 504 | {
"text": [
"New conjugate vaccines against Haemophilus influenzae type b and Streptococcus pneumoniae have contributed to decreases in radiologic, clinical and complicated pneumonia cases"
],
"answer_start": [
566
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} |
2,592 | A mathematical model for simulating the phase-based transmissibility of a novel coronavirus
https://doi.org/10.1186/s40249-020-00640-3
SHA: 018269476cd191365d6b8bed046078aea07c8c01
Authors: Yin, Tian-Mu Chen; Jia, Rui; Qiu-Peng, Wang; Ze-Yu, Zhao; Jing-An, Cui; Ling
Date: 2020
DOI: 10.1186/s40249-020-00640-3
License... | What was the objective of the study? | false | 2,777 | {
"text": [
"provide a mathematical model for calculating the transmissibility of SARS-CoV-2"
],
"answer_start": [
18174
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} |
1,620 | A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761721/
SHA: f4cebabd74b16e710fb41a737d8ef84b7d565d8d
Authors: Banks, G; Lassi, G; Hoerder-Suabedissen, A; Tinarelli, F; Simon, M M; Wilcox, A; Lau, P; Lawson, T N; Johnson, S; Rutma... | What CNS functions can be measured by studying the movement of mice in a T-maze? | false | 931 | {
"text": [
"working memory and spatial memory"
],
"answer_start": [
11976
]
} |
2,628 | Haunted with and hunting for viruses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089303/
SHA: c51c4f6146d0c636bc4dc3839c16b9e3ef52849a
Authors: Gao, George Fu; Wu, Ying
Date: 2013-08-07
DOI: 10.1007/s11427-013-4525-x
License: cc-by
Abstract: nan
Text: pecially with next-generation sequencing (NGS) for new virus ... | What serious question was raised? | false | 3,847 | {
"text": [
"as to whether or not our seasonal or pandemic flu might have another reservoir host."
],
"answer_start": [
464
]
} |
2,565 | Interferon-Induced Transmembrane Protein 3 Inhibits Hantaan Virus Infection, and Its Single Nucleotide Polymorphism rs12252 Influences the Severity of Hemorrhagic Fever with Renal Syndrome
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206578/
SHA: 4328e18bdf9b52875c87f3f5ddb1911636a192d2
Authors: Xu-yang, Zheng; Pei... | What diagnostic test is correlated with the severity of HFRS? | false | 549 | {
"text": [
"plasma viral load"
],
"answer_start": [
25635
]
} |
1,579 | Viral Respiratory Tract Infections in Adult Patients Attending Outpatient and Emergency Departments, Taiwan, 2012–2013: A PCR/Electrospray Ionization Mass Spectrometry Study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635751/
SHA: ef6361c7bffb9e92f397d7004bfb3a9c804d7c6a
Authors: Shih, Hsin-I; Wang, Hsuan-Chen; Su... | What was the most frequent coinfection? | false | 4,085 | {
"text": [
"rhinovirus"
],
"answer_start": [
20799
]
} |
2,683 | Estimating the number of infections and the impact of non-
pharmaceutical interventions on COVID-19 in 11 European countries
30 March 2020 Imperial College COVID-19 Response Team
Seth Flaxmani Swapnil Mishra*, Axel Gandy*, H JulietteT Unwin, Helen Coupland, Thomas A Mellan, Harrison
Zhu, Tresnia Berah, Jeffrey W Eato... | What is Belgium's estimated mean percentage [95% credible interval] of total population infected as of 28th March? | false | 848 | {
"text": [
"3.7% [1.3%-9.7%]"
],
"answer_start": [
13114
]
} |
1,689 | Chikungunya: A Potentially Emerging Epidemic?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860491/
SHA: f7c3160bef4169d29e2a8bdd79dd6e9056d4774c
Authors: Thiboutot, Michelle M.; Kannan, Senthil; Kawalekar, Omkar U.; Shedlock, Devon J.; Khan, Amir S.; Sarangan, Gopalsamy; Srikanth, Padma; Weiner, David B.; Muthumani... | What percentage of the patients still have the CHIKV IgM after eighteen months? | false | 2,499 | {
"text": [
"The chronic stage of CHIKF is characterized by"
],
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2,486 | Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review
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1,652 | Deep sequencing of primary human lung epithelial cells challenged with H5N1 influenza virus reveals a proviral role for CEACAM1
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2,634 | Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
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Authors: Chan, Jasper Fuk-Woo; Kok, Kin-Hang; Zhu, Zheng; Chu, Hin; To, Kelv... | Which strains do not have such deletions? | false | 3,726 | {
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1,566 | Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720120/
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Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni... | What can respiratory viruses cause? | false | 1,611 | {
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1,671 | Host resilience to emerging coronaviruses
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DOI: 10.2217/fvl-2016-0060
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Abstract: Recently, two coronaviruses, severe acute respiratory syndrome coronavirus an... | What percentage of people infected with MERS-CoV died? | false | 1,256 | {
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2,684 | 1918 Influenza: the Mother of All Pandemics
Jeffery K. Taubenberger" and David M. Morens1-
The “Spanish" influenza pandemic of 1918—1919,
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origins, its unusual epidemiologic features, and the basis of
its p... | What was the primary difference between the first wave and the 2nd and 3rd wave of the 1918-1919 swine flu pandemic? | false | 1,094 | {
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1,660 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
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Authors: Hjelle, Brian; Torres-Pérez, Fernando
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DOI: 10.3390/v2122559
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Abstract: The continued emergence and re-emergenc... | Which new genus was the virus later found to represent? | false | 4,466 | {
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1,741 | MERS coronavirus: diagnostics, epidemiology and transmission
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Authors: Mackay, Ian M.; Arden, Katherine E.
Date: 2015-12-22
DOI: 10.1186/s12985-015-0439-5
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Abstract: The first known cases of Middle East ... | Which city harbours a wide range of MERS-CoV variants | false | 4,375 | {
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1,689 | Chikungunya: A Potentially Emerging Epidemic?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860491/
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Authors: Thiboutot, Michelle M.; Kannan, Senthil; Kawalekar, Omkar U.; Shedlock, Devon J.; Khan, Amir S.; Sarangan, Gopalsamy; Srikanth, Padma; Weiner, David B.; Muthumani... | How is CHIKV maintained in Africa? | false | 2,481 | {
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1,606 | Serological Assays Based on Recombinant Viral Proteins for the Diagnosis of Arenavirus Hemorrhagic Fevers
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Authors: Fukushi, Shuetsu; Tani, Hideki; Yoshikawa, Tomoki; Saijo, Masayuki; Morikawa, Shigeru
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1,576 | Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats
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188 | The Battle Against Coronavirus Disease 2019 (COVID-19): Emergency Management
and Infection Control in a Radiology Department
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Journal Pre-proof
Zixing Huang, Shuang Zhao, Zhenlin Li, Weixia Chen, Lihong Zhao, Lipeng Deng, Bin
Song
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DOI: htt... | What kind of masks are recommended to protect healthcare workers from COVID-19 exposure? | false | 242 | {
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1,719 | Virus-Vectored Influenza Virus Vaccines
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147686/
SHA: f6d2afb2ec44d8656972ea79f8a833143bbeb42b
Authors: Tripp, Ralph A.; Tompkins, S. Mark
Date: 2014-08-07
DOI: 10.3390/v6083055
License: cc-by
Abstract: Despite the availability of an inactivated vaccine that has been lic... | What does LAIV rely on? | false | 1,488 | {
"text": [
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1,560 | Relationship between hepcidin and oxidant/antioxidant status in calves with suspected neonatal septicemia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146304/
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Authors: Erkilic, E. E.; Erdogan, H. M.; Ogun, M.; Kirmizigul, A. H.; Gokce, E.; Kuru, M.; Kukurt, A.
Date: 201... | Where was hepcidin first discovered? | false | 2,131 | {
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1,594 | Gemcitabine and Nucleos(t)ide Synthesis Inhibitors Are Broad-Spectrum Antiviral Drugs that Activate Innate Immunity
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923505/
SHA: f1e1e2511e051195c8327a56d5c311a2dd4ab6b3
Authors: Shin, Hye Jin; Kim, Chonsaeng; Cho, Sungchan
Date: 2018-04-20
DOI: 10.3390/v10040211
License... | Gemcitabine has been shown to have antiviral activity against which viruses? | false | 5,234 | {
"text": [
"Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), Zika virus (ZIKV), HCV, poliovirus (PV), influenza A virus (IAV), HIV, and enteroviruses (EV)"
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2,437 | Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
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SHA: 1bd2f6497996fc0fccd8dffd7f84846d3d36f964
Authors: Wang, Shaobo; Liu, Yang; Guo, Jiao; Wang, Peilin; Zhang, Leike; Xiao, Gengfu; Wang, Wei
Date: 2017-10-13
DOI: 10.1128/jv... | What is the function of the nonstructural protein elements of the flavivirus? | false | 1,229 | {
"text": [
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2,592 | A mathematical model for simulating the phase-based transmissibility of a novel coronavirus
https://doi.org/10.1186/s40249-020-00640-3
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Authors: Yin, Tian-Mu Chen; Jia, Rui; Qiu-Peng, Wang; Ze-Yu, Zhao; Jing-An, Cui; Ling
Date: 2020
DOI: 10.1186/s40249-020-00640-3
License... | What was the mean delay from symptom onset to detection/hospitalization of a case? | false | 2,765 | {
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1,645 | Pre-existing immunity against vaccine vectors – friend or foe?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542731/
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Authors: Saxena, Manvendra; Van, Thi Thu Hao; Baird, Fiona J.; Coloe, Peter J.; Smooker, Peter M.
Date: 2013-01-27
DOI: 10.1099/mic.0.049601-0
License: cc... | What is the connection between chicken and Salmonella? | false | 872 | {
"text": [
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1,645 | Pre-existing immunity against vaccine vectors – friend or foe?
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Authors: Saxena, Manvendra; Van, Thi Thu Hao; Baird, Fiona J.; Coloe, Peter J.; Smooker, Peter M.
Date: 2013-01-27
DOI: 10.1099/mic.0.049601-0
License: cc... | Is a pre-existing immune response to commonly used delivery vector an advantage or a disadvantage? | false | 800 | {
"text": [
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1,566 | Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus
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Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni... | What are the most common viruses? | false | 1,614 | {
"text": [
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1,741 | MERS coronavirus: diagnostics, epidemiology and transmission
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687373/
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Authors: Mackay, Ian M.; Arden, Katherine E.
Date: 2015-12-22
DOI: 10.1186/s12985-015-0439-5
License: cc-by
Abstract: The first known cases of Middle East ... | How does MARS-COV differ from SARS-COV? | false | 4,380 | {
"text": [
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1,604 | Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
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Authors: Sun, Bing; He, Hangyong; Wang, Zheng; Qu, Jiuxin; Li, Xuya... | Where could a clinician acquire a positive viral sample in severe cases of human adenovirus type 55 (HAdV-55)? | false | 3,251 | {
"text": [
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1,552 | One step closer to an experimental infection system for Hepatitis B Virus? --- the identification of sodium taurocholate cotransporting peptide as a viral receptor
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SHA: f4f36a8e9fee64d59ccf22b724c7dab345102658
Authors: Chen, Pei-Jer; Wu, T-C
Date: 2013-01-11
DOI:... | Which protein domain of the Hepatitis B envelope is necessary for infection? | false | 2,998 | {
"text": [
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2,504 | Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052386/
SHA: 45a566c71056ba4faab425b4f7e9edee6320e4a4
Authors: Tan, Kai Sen; Lim, Rachel Liyu; Liu, Jing; Ong, Hsiao Hui; ... | In addition to worsening disease symptoms, what do viral-induced exacerbations do? | false | 4,027 | {
"text": [
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2,486 | Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review
https://doi.org/10.3390/jcm9030623
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Authors: Pang, Junxiong; Wang, Min Xian; Ang, Ian Yi Han; Tan, Sharon Hui Xuan; Lewis, Ruth Frances; Chen, Jacinta I. Pei;... | What studies were excluded? | false | 3,630 | {
"text": [
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2,504 | Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052386/
SHA: 45a566c71056ba4faab425b4f7e9edee6320e4a4
Authors: Tan, Kai Sen; Lim, Rachel Liyu; Liu, Jing; Ong, Hsiao Hui; ... | What are both IFV and RSV infections shown to do? | false | 4,014 | {
"text": [
"to increase miR-21 and augmented inflammation in experimental murine asthma models, which is reversed with a combination treatment of anti-miR-21 and corticosteroids"
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2,669 | Frontiers in antiviral therapy and immunotherapy
https://doi.org/10.1002/cti2.1115
SHA: facbfdfa7189ca9ff83dc30e5d241ab22e962dbf
Authors: Heaton, Steven M
Date: 2020
DOI: 10.1002/cti2.1115
License: cc-by
Abstract: nan
Text: Globally, recent decades have witnessed a growing disjunction, a 'Valley of Death' 1,2 no l... | In this way, what do the mRNA-destabilising RBPs constitute ? | false | 4,149 | {
"text": [
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1,660 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | Among zoonotic diseases, what are hosts of several pathogenic RNA viruses? | false | 4,457 | {
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2,504 | Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052386/
SHA: 45a566c71056ba4faab425b4f7e9edee6320e4a4
Authors: Tan, Kai Sen; Lim, Rachel Liyu; Liu, Jing; Ong, Hsiao Hui; ... | What is the viral involvement in COPD exacerbation? | false | 3,872 | {
"text": [
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1,741 | MERS coronavirus: diagnostics, epidemiology and transmission
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687373/
SHA: f6fcf1a99cbd073c5821d1c4ffa3f2c6daf8ae29
Authors: Mackay, Ian M.; Arden, Katherine E.
Date: 2015-12-22
DOI: 10.1186/s12985-015-0439-5
License: cc-by
Abstract: The first known cases of Middle East ... | How long after Infectious MERS-CoV added to DC, goat or cow milk and stored at 22°C could be recovered? | false | 4,283 | {
"text": [
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1,557 | Changes in pulmonary tuberculosis prevalence: evidence from the 2010 population survey in a populous province of China
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890533/
SHA: eef61bdfa49b8652fd660b5b8b7e74cf51922505
Authors: Wei, Xiaolin; Zhang, Xiulei; Yin, Jia; Walley, John; Beanland, Rachel; Zou, Guanyang; Zha... | How was the survey designed? | false | 3,018 | {
"text": [
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1,719 | Virus-Vectored Influenza Virus Vaccines
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147686/
SHA: f6d2afb2ec44d8656972ea79f8a833143bbeb42b
Authors: Tripp, Ralph A.; Tompkins, S. Mark
Date: 2014-08-07
DOI: 10.3390/v6083055
License: cc-by
Abstract: Despite the availability of an inactivated vaccine that has been lic... | How safe is NYVAC? | false | 1,643 | {
"text": [
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2,634 | Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067204/
SHA: c097a8a9a543d69c34f10e5c3fd78019e560026a
Authors: Chan, Jasper Fuk-Woo; Kok, Kin-Hang; Zhu, Zheng; Chu, Hin; To, Kelv... | What is responsible for the interaction with host receptor? | false | 3,722 | {
"text": [
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1,660 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What is the case-fatality ratios, for the most common viral serotypes? | false | 4,448 | {
"text": [
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1,629 | The Intranasal Application of Zanamivir and Carrageenan Is Synergistically Active against Influenza A Virus in the Murine Model
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459876/
SHA: f0b1fa4036434b57c8307d43c39a4193f7e8053a
Authors: Morokutti-Kurz, Martina; König-Schuster, Marielle; Koller, Christiane; Graf, Chr... | What was the mortality rate of influenza a virus subtype h7n9 (avian or bird flu)? | false | 2,144 | {
"text": [
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1,660 | Hantaviruses in the Americas and Their Role as Emerging Pathogens
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185593/
SHA: efe13a8d42b60ef9f7387ea539a1b2eeb5f80101
Authors: Hjelle, Brian; Torres-Pérez, Fernando
Date: 2010-11-25
DOI: 10.3390/v2122559
License: cc-by
Abstract: The continued emergence and re-emergenc... | What does the virus seed? | false | 4,546 | {
"text": [
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2,504 | Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052386/
SHA: 45a566c71056ba4faab425b4f7e9edee6320e4a4
Authors: Tan, Kai Sen; Lim, Rachel Liyu; Liu, Jing; Ong, Hsiao Hui; ... | What will the review focus on? | false | 3,892 | {
"text": [
"compiling and collating the current known mechanisms of viral-induced exacerbation of chronic airway inflammatory diseases; as well as linking the different viral infection pathogenesis to elucidate other potential ways the infection can exacerbate the disease"
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1,719 | Virus-Vectored Influenza Virus Vaccines
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147686/
SHA: f6d2afb2ec44d8656972ea79f8a833143bbeb42b
Authors: Tripp, Ralph A.; Tompkins, S. Mark
Date: 2014-08-07
DOI: 10.3390/v6083055
License: cc-by
Abstract: Despite the availability of an inactivated vaccine that has been lic... | Which is the most studied serotype? | false | 1,501 | {
"text": [
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1,689 | Chikungunya: A Potentially Emerging Epidemic?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860491/
SHA: f7c3160bef4169d29e2a8bdd79dd6e9056d4774c
Authors: Thiboutot, Michelle M.; Kannan, Senthil; Kawalekar, Omkar U.; Shedlock, Devon J.; Khan, Amir S.; Sarangan, Gopalsamy; Srikanth, Padma; Weiner, David B.; Muthumani... | What did this mutation allow? | false | 2,510 | {
"text": [
"CHIKV's secondary vector species, Ae. albopictus, to supplement Ae. aegypti as its primary vector"
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1,560 | Relationship between hepcidin and oxidant/antioxidant status in calves with suspected neonatal septicemia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146304/
SHA: efcd7d171bb51acf2ef0a631901900497957a3be
Authors: Erkilic, E. E.; Erdogan, H. M.; Ogun, M.; Kirmizigul, A. H.; Gokce, E.; Kuru, M.; Kukurt, A.
Date: 201... | What organ produces hepcidin? | false | 2,132 | {
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1,656 | Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541410/
SHA: f2fcc16391f946c99717b63ec9a24e5384aac381
Authors: Zhu, Xiaojie; Zhu, Yun; Ye, Sheng; Wang, Qian; Xu, Wei; ... | What is labeled in pink? | false | 2,254 | {
"text": [
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} |
1,629 | The Intranasal Application of Zanamivir and Carrageenan Is Synergistically Active against Influenza A Virus in the Murine Model
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459876/
SHA: f0b1fa4036434b57c8307d43c39a4193f7e8053a
Authors: Morokutti-Kurz, Martina; König-Schuster, Marielle; Koller, Christiane; Graf, Chr... | Did the use of carageenan play a role in pandemic's caused by novel viruses? | false | 2,182 | {
"text": [
"A second scope of this combination is the protection against newly emerging pandemic viruses during the time until identification of the virus followed by manufacturing and distribution of vaccines"
],
"answer_start": [
32767
]
} |
1,607 | A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967396/
SHA: f1f24521928f5d8565a15a17bd7f79239a3d4116
Authors: Hajrezaie, Maryam; Paydar, Mohammadjavad; Zorofchian Moghadamtousi, Soheil;... | What types of cells are suitable for colon cancer studies? | false | 5,284 | {
"text": [
"HT-29 cells"
],
"answer_start": [
19277
]
} |
1,676 | Viruses Causing Gastroenteritis: The Known, The New and Those Beyond
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776197/
SHA: f7b30ee89775bc82607cc6bc87feb5934b47625f
Authors: Oude Munnink, Bas B.; van der Hoek, Lia
Date: 2016-02-19
DOI: 10.3390/v8020042
License: cc-by
Abstract: The list of recently discovered ga... | What is Universal primer-PCR used for in viral studies? | false | 906 | {
"text": [
"detect novel variants"
],
"answer_start": [
8039
]
} |
630 | Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752805/
Boily-Larouche, Geneviève; Iscache, Anne-Laure; Zijenah, Lynn S.; Humphrey, Jean H.; Mouland, Andrew J.; Ward, Brian J.; Roger, Michel
2009-10-07
DOI:10.1371/journal.... | How does the presence of DC-SIGNR affect the MTCT of HIV-1? | false | 306 | {
"text": [
"the presence of DC-SIGNR at the placental endothelial cell surface may protect infants from HIV-1 infection by capturing virus and promoting its degradation/presentation."
],
"answer_start": [
28910
]
} |
2,684 | 1918 Influenza: the Mother of All Pandemics
Jeffery K. Taubenberger" and David M. Morens1-
The “Spanish" influenza pandemic of 1918—1919,
which caused :50 million deaths worldwide, remains an
ominous warning to public health. Many questions about its
origins, its unusual epidemiologic features, and the basis of
its p... | Was the 1918 swine flu virus novel to humans are was it derived from older viruses? | false | 1,107 | {
"text": [
"Viral sequence data now suggest that the entire 1918\nVirus was novel to humans in, or shortly before, 1918, and\nthat it thus was not a reassortant Virus produced from old\nexisting strains that acquired 1 or more new genes"
],
"answer_start": [
14934
]
} |
1,719 | Virus-Vectored Influenza Virus Vaccines
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147686/
SHA: f6d2afb2ec44d8656972ea79f8a833143bbeb42b
Authors: Tripp, Ralph A.; Tompkins, S. Mark
Date: 2014-08-07
DOI: 10.3390/v6083055
License: cc-by
Abstract: Despite the availability of an inactivated vaccine that has been lic... | What was the failure of rAd5 vaccine for inducing HIV-1 specific T cell response? | false | 1,535 | {
"text": [
"the study was stopped after interim analysis suggested the vaccine did not achieve efficacy and individuals with high preexisting Ad5 antibody titers might have an increased risk of acquiring HIV-1"
],
"answer_start": [
10868
]
} |
1,553 | Development of an ELISA-array for simultaneous detection of five encephalitis viruses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305475/
SHA: ef2b8f83d5a3ab8ae35e4b51fea6d3ed9eb49122
Authors: Kang, Xiaoping; Li, Yuchang; Fan, Li; Lin, Fang; Wei, Jingjing; Zhu, Xiaolei; Hu, Yi; Li, Jing; Chang, Guohui; Zhu, Qingyu... | What are the current clinically-available methods to detect encephalitis viral antigens? | false | 3,004 | {
"text": [
"ELISA and IFA"
],
"answer_start": [
2177
]
} |
1,580 | Isothermal Amplification Using a Chemical Heating Device for Point-of-Care Detection of HIV-1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285652/
SHA: ef7110a9022bac2e50c995b0f6b826ff071e48f8
Authors: Curtis, Kelly A.; Rudolph, Donna L.; Nejad, Irene; Singleton, Jered; Beddoe, Andy; Weigl, Bernhard; LaBarre, Paul;... | What was used to measure the performance of the NINA heaters? | false | 4,436 | {
"text": [
"whole blood specimens"
],
"answer_start": [
1751
]
} |
1,719 | Virus-Vectored Influenza Virus Vaccines
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147686/
SHA: f6d2afb2ec44d8656972ea79f8a833143bbeb42b
Authors: Tripp, Ralph A.; Tompkins, S. Mark
Date: 2014-08-07
DOI: 10.3390/v6083055
License: cc-by
Abstract: Despite the availability of an inactivated vaccine that has been lic... | What is NYVAC? | false | 1,640 | {
"text": [
"The NYVAC vector is a highly attenuated vaccinia virus strain. NYVAC is replication-restricted"
],
"answer_start": [
32395
]
} |
2,440 | Optimization Method for Forecasting Confirmed Cases of COVID-19 in China
https://doi.org/10.3390/jcm9030674
SHA: 1d7f8850c5244fdc9b387038e7eeae9bcbbde6d2
Authors: Al-Qaness, Mohammed A. A.; Ewees, Ahmed A.; Fan, Hong; Abd El Aziz, Mohamed
Date: 2020
DOI: 10.3390/jcm9030674
License: cc-by
Abstract: In December 2019,... | How was the proposed model tested? | false | 4,402 | {
"text": [
"using two different datasets of weekly influenza confirmed cases in two countries, namely the USA and China"
],
"answer_start": [
1722
]
} |
1,719 | Virus-Vectored Influenza Virus Vaccines
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147686/
SHA: f6d2afb2ec44d8656972ea79f8a833143bbeb42b
Authors: Tripp, Ralph A.; Tompkins, S. Mark
Date: 2014-08-07
DOI: 10.3390/v6083055
License: cc-by
Abstract: Despite the availability of an inactivated vaccine that has been lic... | Why is the VEE replicon system particularly appealing? | false | 1,570 | {
"text": [
"the VEE targets antigen-presenting cells in the lymphatic tissues, priming rapid and robust immune responses"
],
"answer_start": [
18262
]
} |
1,719 | Virus-Vectored Influenza Virus Vaccines
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147686/
SHA: f6d2afb2ec44d8656972ea79f8a833143bbeb42b
Authors: Tripp, Ralph A.; Tompkins, S. Mark
Date: 2014-08-07
DOI: 10.3390/v6083055
License: cc-by
Abstract: Despite the availability of an inactivated vaccine that has been lic... | What gives protection against clinical disease? | false | 1,475 | {
"text": [
"serum antibodies"
],
"answer_start": [
3812
]
} |
630 | Functional Genetic Variants in DC-SIGNR Are Associated with Mother-to-Child Transmission of HIV-1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752805/
Boily-Larouche, Geneviève; Iscache, Anne-Laure; Zijenah, Lynn S.; Humphrey, Jean H.; Mouland, Andrew J.; Ward, Brian J.; Roger, Michel
2009-10-07
DOI:10.1371/journal.... | How does Mannanose Binding Lectin (MBL) affect elimination of HIV-1 pathogen? | false | 318 | {
"text": [
"Mannose-binding lectin (MBL) is an innate immune receptor synthesised in the liver and secreted in the bloodstream in response to inflammation signal. MBL promotes pathogen elimination by opsonization and phagocytosis,"
],
"answer_start": [
28335
]
} |
1,652 | Deep sequencing of primary human lung epithelial cells challenged with H5N1 influenza virus reveals a proviral role for CEACAM1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195505/
SHA: ef58c6e981a08c85d2c0efb80e5b32b075f660b4
Authors: Ye, Siying; Cowled, Christopher J.; Yap, Cheng-Hon; Stambas, John
Date: 2018-10-... | What mediates the anti-apoptosis of neutrophils? | false | 1,951 | {
"text": [
"Phosphorylation of CEACAM1 ITIM motifs and activation of caspase-3"
],
"answer_start": [
27479
]
} |
2,504 | Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052386/
SHA: 45a566c71056ba4faab425b4f7e9edee6320e4a4
Authors: Tan, Kai Sen; Lim, Rachel Liyu; Liu, Jing; Ong, Hsiao Hui; ... | What does the the inflammatory environment dispersal of upper airway commensals into the lower airway cause? | false | 4,005 | {
"text": [
"inflammation and alteration of the lower airway environment, resulting in prolong exacerbation episodes following viral infection."
],
"answer_start": [
26671
]
} |
1,679 | Venezuelan Equine Encephalitis Virus Induces Apoptosis through the Unfolded Protein Response Activation of EGR1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794670/
SHA: f4aa788ab898b28b00ee103e4d4ab24a2c684caf
Authors: Baer, Alan; Lundberg, Lindsay; Swales, Danielle; Waybright, Nicole; Pinkham, Chelsea; Dinman, Jo... | Where does EGR1 accumulate in the cell? | false | 942 | {
"text": [
"nucleus"
],
"answer_start": [
33361
]
} |
2,486 | Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review
https://doi.org/10.3390/jcm9030623
SHA: 9b0c87f808b1b66f2937d7a7acb524a756b6113b
Authors: Pang, Junxiong; Wang, Min Xian; Ang, Ian Yi Han; Tan, Sharon Hui Xuan; Lewis, Ruth Frances; Chen, Jacinta I. Pei;... | What is a key limitation of serological testing? | false | 3,662 | {
"text": [
"the need to collect paired serum samples (in the acute and convalescent phases) from cases under investigation for confirmation to eliminate potential cross-reactivity from non-specific antibodies from past exposure and/or infection by other coronaviruses."
],
"answer_start": [
17837
]
} |
1,741 | MERS coronavirus: diagnostics, epidemiology and transmission
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687373/
SHA: f6fcf1a99cbd073c5821d1c4ffa3f2c6daf8ae29
Authors: Mackay, Ian M.; Arden, Katherine E.
Date: 2015-12-22
DOI: 10.1186/s12985-015-0439-5
License: cc-by
Abstract: The first known cases of Middle East ... | What is the progression of symptoms to disease? | false | 4,214 | {
"text": [
"Fever and gastrointestinal symptoms may form a prodrome, after which symptoms decline, only to be followed by a more severe systemic and respiratory syndrome"
],
"answer_start": [
6496
]
} |
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