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Snowstorm appearance on ultrasonography is seen in-
Ans. is 'd' i.e., Molar pregnancy * "Snow storm appearance" or "bunch of grapes appearance" is characteristic of H. mole.
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Which of the following region of spine is most commonly affected in rheumatoid ahritis?
Rheumatoid ahritis principally involves atlantoaxial joint of cervical spine. Atlantoaxial involvement of the cervical spine result in compressive myelopathy and neurologic dysfunction. Rheumatoid ahritis does not affect thoracic and lumbar spine except in unusual circumstances. Reference: Harrison's Principles of Inte...
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Compared to hydrocoisone, maximum glucocoicoid activity is seen in ?
Ans. is 'c' i.e., Dexamethasone
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All are causes of primary amenorrhea EXCEPT
Sheehan's syndrome Post paum pitutary necrosis. Occurs as a result of ischemic pituitary necrosis due to severe postpaum hemorrhage Presents as failure to lactate or to resume menses (Secondary amenorrhea) Other presentation: genital and axillary hair loss, asthenia and weakness, fine wrinkles around the eyes and lips,...
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Minimum interval between 2 live vaccine immunization -
Ans. is 'b1 i.e., 4 weeks Basic principle of immunezationMinimum 4 week interval recommended between 2 live vaccine adminstration except OPVand oral thyphoid.Two or more killed vaccine may be administrated simultaneously or at any given internalA live and killed vaccine given simultaneously but at different site.If imm...
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Opsnins is -
Ans. is 'a' i.e., C3a Opsonin o A Substance capable of enhancing phagocytosis. o Complement (C3a) and antibodies are the two main opsonins.
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With a sensitive test, hCG can be detected in maternal serum or urine by ------ after ovulation?
Detection of hCG in maternal blood and urine is the basis for endocrine assays of pregnancy. Syncytiotrophoblasts produce hCG in amounts that increase exponentially during the first trimester following implantation. With a sensitive test, the hormone can be detected in maternal serum or urine by 8 to 9 days after ovula...
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Normal respiratory minute volume is?
Ans. (a) Tidal Volume X Respiratory RateRef: Ganong 25th ed. 1629RMV: Respiratory minute volume: 500ml X 12 breaths/ min= 6L
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Which of the following is known as the "guardian of the genome"-
The discovery of the tumor suppressor protein known as p53, and the process of uneahing its functions came about as a result the effos of thousands of scientists around the globe. In p53: The Gene that Cracked the Cancer Code, science writer Sue Armstrong takes a fresh look at the exciting breakthroughs and disappointi...
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Which of the following hormone does not act through c-AMP:
GH
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Not a feature of Vogt Kayanagi Harada Syndrome is
Features of Vogt Kayanagi Harada Syndrome include Mental retardation.
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Most common site for carcinoid tumor in the abdomen
.CARCINOID TUMOUR It commonly occurs in appendix (65%), ileum (25%), other pas of GIT and rarely bronchus, testis, ovary. In the small intestine, carcinoids are most often seen within the terminal 2 feet of the ileum. * They arise from the enterochromaffin cells (Kulchitsky cells) found in the crypts of Lieberkuhn. * T...
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Which of the following drugs inhibit platelet cyclooxygenase reversibly?
NSAID'S Inhibit COX enzyme reversibly, Except Aspirin which is an irreversible inhibitor of this enzyme . Alprostadil -PGE1 and prednisolone do not inhibit cox enzyme .
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All of the following are bullous lesions except -
Primary blistering disorder Intraepidermal → Pemphigus vulgaris, P. foliaceous, P. vegetans, P. erythematosus. Subepidermal → Bullous pemphigoid, Dermatitis herpe4formis, Epidermolysis bullosa acquisita.
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Not a dietary source of vit. B12-
Ans. is 'c' ie. Soyabean Vit B12 is present in foods of animal origin and is not present in foods of vegetable sources.
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Intussusception is associated with:
Ref: Bailey & Love's Short Practice of Surgery 25th Edition Chapter 66 Intestinal Obstruction Pages 1191-12 & Donald A, Antonio!i, " Gastrointestinal Autonomic Nerve Tumors, expanding the spectrum of gastrointestinal stromal tumors," Arch Pathol Lab Med: 1989: 113: 831-833.Explanation:IntussusceptionInvagination of an ...
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'Shrinking lung' is a feature of
Shrinking lung syndrome (SLS) is a rare complication of systemic lupus erythematosus (SLE) characterized by unexplained dyspnea, a restrictive pattern on pulmonary function tests, and an elevated hemidiaphragm.. This disorder is seen primarily during the later stages of SLE Ref Davidson 23rd edition pg 533
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A 40 years old patient who has been consuming cannabis regularly for last 20 years comes to you in withdrawal. What is the most frequently seen withdrawal symptom?
Irritability is the most common cannabis withdrawal syndrome Withdrawal symptoms- Irritability Depressed mood Sleep disturbances Headache
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True regarding comparison values of cow and human milk are all except: March 2012
Ans: D i.e. Human milk has comparatively less of lactose Comparison of human and cow link Protein in human milk is 1.1 g, whereas in cow milk it is 3.2 Calcium in human milk is 28 mg, whereas in cow milk it is 120 mg Minerals in human milk is 0.1 g, whereas in cow milk it is 0.8 g Lactose in human milk is 7.4 g, wherea...
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Most impoant element in treatment of diphtheria ?
Ans. is 'a' i.e., Antitoxin Treatment of diphtheria . Administration of diphtherial antitoxin is the most impoant element in the treatment of respiratory diphtheria. . The primary goal of antibiotic therapy is to eradicate C. diphtheriae. Drugs currently used are erythromycin or procaine penicillin G. alternatives are ...
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Which of the following drug is not needed to be present in tubular lumen for diuretic action?
Aldosterone receptor antagonist Osmotic diuretics Carbonic anhydrase inhibitor Thiazides spironolactone, eplerenone inhibit the aldosterone channels located on the basal side cells of collecting tubule, so they are not secreted in lumen. They filter across the glomerulus and in the nephron it will attract water, so it ...
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A patient presents to emergency with pinpoint pupil, salivation, lacrimation, tremors and red tears. Plasma cholinesterase level was 30% of normal. Most probable Diagnosis is:
Ans. (A) Organophosphate poisoning(Ref: Katzung 12/e p110)These are characteristic features of anti-cholinestearse (organophosphate and carbamate) poisoning.Features of Organophosphate poisoning:* Muscarinic symptoms: Pin point pupil, salivation, lacrimation, urination, defecation, gastrointestinal distress, vomiting, ...
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Mid day meal programme comes under ?
Ans. is 'b' i.e., Ministry of education
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Two important byproducts of HMP shunt are
The HMP shunt pathway has oxidative and non-oxidative phases. During the oxidative phase, glucose-6-phosphate is oxidized with the generation of 2 molecules of NADPH, and one molecule of pentose phosphate, with the liberation of one molecule of CO2. During the non-oxidative phase, the pentose phosphates are converted t...
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Propronolol is useful in all except -
Ans. is 'b' i.e., Parkinsonian tremor o Propranolol inhibits the tremors which are due to overactivity of adrenergic system b 2-receptor), e.g. in thyrotoxicosis. o But, parkinsonian tremor and intention tremor are not due to sympathetic overactivity --> b -blocker has no role. b -blockers are DOC for HOCM and for cont...
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Vasa pre in a term gestation is managed by __________
Vasa Pre in a term gestation is managed by immediate LSCS. Management of vasa pre: Confirmed vasa pre not bleeding: Admit at 28-32 weeks, plan elective CS depending on fetal lung maturity Bleeding vasa pre: Delivery should be done by category 1 Emergency CS. (Categories based on urgency such as emergency, urgency, sche...
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Risk factor for bladder carcinoma is -
Ans. is 'b' i.e., Schistosoma hematobium Risk factors for ca of BladderCigarette smoking is the main etiological factor and accounts for about 50% of bladder cancers.Occupational exposures to chemicalso The following compounds mav be carcinogenic # 2 naphthylamine-combustion gases and soot from coal# 4-aminobiphenyl-ch...
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most coomon benign tumor of parotid gland?
Pleomorphic Adenoma : Epithelial Components Tubular and cord-like arrangements Cells contain a moderate amount of cytoplasm Mitoses are rare Stromal or "mesenchymal" Components Can be quite variable Attributable to the myoepithelial cells Most tumors show chondroid (cailaginous) differentiation Osseous metaplasia not u...
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All are example for randomised control trials except-
.the major type of randomised controlled trials includes, 1.clinical trials 2.preventive trials. 3.risk factor trials 4.cessation experimnts 5.trial of aetiological agents. 6.evaluation of health services. ref:park&;s textbook,ed 22,pg no 82
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Stain used for the diagnosis of granulocytic sarcoma
.
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Six penny bruise is seen in ?
Ans. is 'a' i.e., Manual strangulation Six penny bruiseThese are discoid shaped bruises of about 1 cm in diameter resulted from fingeip pressure usually seen in neck region because of manual strangulation. These are called six penny bruise because of resemblance with six penny.
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Which of the following is not a Deep Lymphoid tissue
Mucosa-associated lymphoid tissue (MALT): Small numbers of lymphocytes may be present almost anywhere in the body, but signifi cant aggregations are seen in relation to the mucosa of the respiratory, alimentary and urogenital tracts. These aggregations are referred to as MALT. Mucosa-associated lymphoid tissue in the r...
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On ECG, ST segment elevation is seen in all of the following conditions except: March 2012
Ans: D i.e. Hypocalcemia ECG changes and conditions ST elevation may signify myocardial infarction, pericarditis or left ventricular aneurysm QT prolongation may occur with congenital long QT syndrome, low potassium, low magnesium, low calcium etc.
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Patient presented with loss of sensations in the lateral three and a half fingers. Which of the following will be an additional finding in this patient?
This is the case of median nerve injury; sensation is lost over area supplied by median nerve. Findings: Injury or compression of median nerve at wrist (e.g. Carpal tunnel syndrome) can be tested by 1. Pen test for abductor pollicis brevis there is inability to touch the pen kept above the palm by thumb abduction 2. Ap...
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. In myocardial infarction, early light microscopic change is -
Ans. is 'a' i.e., Waviness of fibres
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The small intestine is characterized by basal crypts and superficial villi (Figure below). Where does cell division take place?Schematic representation of villi and crypts of Lieberkuhn
Small-bowel turnover can be measured in rats by autoradiographic studies in which turnover of cells located in the crypts migrate along the villus toward the tip over a 2- to 3- day period. Intestinal villous mucosa undergoes hypertrophy and hyperplasia whenever an increased food load continuously enters the small inte...
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Aschoff bodies in Rheumatic hea disease show all of the following features, except -
Ans. is 'b' i.e., Epitheloid cell
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Rituximab is used in all except
Ans. is 'b' i.e. PNH Cancer cells express a variety of antigen.These antigens can be targeted by certain antibodies which are specifically directed towards those antigens. The antigen antibody reaction leads to death of the cancer cells.Antibodies {monoclonal antibodies) are now being prepared by immunizing mice agains...
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Following are true about case control study except-
Case control studies often retrospective studies are common first approach to test causal hypothesis. In recent years, case control study has emerged as a permanent method of epidemiological investigation. Both exposure and outcome has occurred before the study. Study proceeds backwards from effect to cause. It uses a ...
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Which of the following is a suicidal enzyme
Cyclooxygenase is a "Suicide Enzyme""Switching off " of prostaglandin activity is paly achieved by a remarkable propey of cyclooxygenase--that of self-catalyzed destruction; that is, it is a "suicide enzyme." Fuhermore, the inactivation of prostaglandins by 15-hydroxyprostaglandin dehydrogenase is rapid. Blocking the a...
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The predominant symptom/sign of pheochromocytoma is:
Answer is D (Episodic Hypeension): The predominant manifestation of Pheochromocytoma is Hypeension which classically presents as Episodic Hypeension (Sustained Hypeension and Ohostatic Hypotension may also be seen). 'The dominant sign is Hypeension. Classically patients have episodic hypeension, but sustained hypeensio...
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Which of the following statements concerning the lateral horn of the spinal cord is true
It gives rise to preganglionic sympathetic fibers Lateral horns carry the autonomic neurons Posterior horns have sensory & anterior horns have motor neurons.
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Which one of the following immunoglobulins constitutes the antigen binding component of B-cell receptor -a) IgAb) IgDc) IgMd) lgG
B cells display immunoglobulin molecules on their surface. These immunoglobulins serve as receptors for a specific antigen, so that each B cell can respond to only one antigen or a closely related group of antigens. All immature B cells carry Ig M immunoglobulins on their surface and most also early Ig D. Combination o...
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The following marker is used to assess the monoclonality in T-cells -
Molecular analysis of the rearrangement in T cell population can distinguish polyclonal lymphocyte proliferations from monoclonal expansions. Reference :Robbins basic pathology 9th edition pg no 100:
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All are features of septic tank except:
SEPTIC TANK: Is a water-tight masonary tank into which household sewage is admitted for treatment Is a satisfactory method of disposing liquid and excreta wastes from individuals dwellings, small groups of houses or institutions which have &;adequate water supply but donot have access to a public sewerage system&; Desi...
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a patient of age 65 years , who is obesity of bmi >40 , known diabetic and hypeensive .patient complaints of breathlessness , excessive sleeping during morning time with headache and with mood swings, what is drug that helps in resolving the symptoms ?
OSA-obstructive sleep apnea #Pathophysiology of OSA Tissue laxity and redundant mucosa Normal Anatomic abnormalities * Decreased muscle tone with REM sleep """&;"&;n * Airway collars, * Desaturation ( 02 ) * Arousal with restoration of airway * Sleep Fragmentation leading to Hypersomnoien, * Clinical features of Obstru...
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in census literacy rate is assessed by:
Ans: C (Ability to read and write) Ref: Textbook of Preventive and Social Medicine, K Park. 22nd edition. page no 44 7Explanation:Census is conducted once in 10 years in India.Literacy rate is assessed those above 7 years ageIn census it was first used in 1991 censusA person who can read and write with understanding in...
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Influenza virus has?
Influenza virus jad ss RNA , it is segmented& exists ad right piece REF:ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.497
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Chignon is:
A vacuum is applied (usually 0.2 kg/cm2 for vacuum extraction of a baby). The scalp is sucked into the cup and an artificial caput is produced. This chignon usually disappears in a few hours.
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Gerlach tonsil is
A collection of lymphoid tissue is present in the nasopharynx, behind the tubal opening. It is called the tubal tonsil, also known as Gerlach tonsil. It is continuous with the lateral pa of the pharyngeal tonsil. In Waldeyer's lymphatic ring, the most impoant aggregations are the right and left palatine tonsils. Poster...
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Structure related to deltopectoral groove ?
Ans. is b' i.e., Cephalic veinDeltopectoral groove is a groove between deltoid muscle and pectoralis major muscle. It is traversed by cephalic vein
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Hypopigmented patches can be seen in :
D i.e. Naevus anemicus
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Commonest presentation of congenital dislocation of the knee is -
The patient presents with hyperextension deformity of the knee.
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Puscher retinopathy is seen in patients with -
Putscher's retinopathy is a disease where pa of the eye (retina) is damaged. Usually associated with severe head injuries, it may also occur with other types of trauma, such as long bone fractures, or with several non-traumatic systemic diseases. However, the exact cause of the disease is not well understood. There are...
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Mutation in which of the following gene is found in Marfan's syndrome?
Marfan's syndrome is caused by recurrent de novo missense mutation in the fibrillin-1 gene. Fibrillin1 is a large glycoprotein that is a structural component of microfibrils. Fibrillin 1 is found in the zonular fibers of the lens, in the periosteum and elastin fibers of aoa. Defect in fibrillin gene accounts for the ma...
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Select inappropriate statement regarding Cholera
Cholera: - Caused by Vibrio cholera - ELTOR - MC subtype in India now. - Route of transmission - FECO-ORAL ROUTE - I.P - 1-2 days - Clinical feature: Rice-watery diarrhea - It is a notifiable disease locally, nationally and internationally. Groups Antibiotic of choice for cholera Adults Doxycycline Children Azithromyci...
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A 34-year-old man presents with a 5-month history of weakness and fatigue. There is no history of drug or alcohol abuse. A CBC shows megaloblastic anemia and a normal reticulocyte count. Further laboratory studies reveal vitamin B12 deficiency Anemia in this patient is most likely caused by which of the following?
Autoimmune gastritis refers to chronic, diffuse inflammatory disease of the stomach that is restricted to the body and fundus and is associated with other autoimmune phenomena. This disorder typically features diffuse atrophic gastritis, antibodies to parietal cells and the intrinsic factor, and increased serum gastrin...
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Circumduction test is used for
Ref : essential ohopaedic maheshwari 9th ed
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Pulled up cecum is seen in
Pulled up conical caecum is the finding seen in ileocaecal TB in Barium study X ray (enteroclysis followed by barium enema or barium meal follow through X ray) Reference : page 584 SRB's manual of surgery 5th edition
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Sturge weber syndrome is associated with –a) Port wine stainb) Cavernous hemangiomac) Lymphangiomad) hemangiosarcoma
Clinical feature of Sturge-weber's syndrome  Unilateral facial nerves (port-wine stain) on upper face and eye lid. Cavernous hemangioma Seizures --> Focal tonic-clonic and contralateral to the site of nerves. Hemiparessis Transient stroke like episodes Visual defects Buphthalmos and glaucoma -k Same side. Mental retar...
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Concentration of which is inversely related to the risk of coronary hea disease
Role of LDL and HDL Recent studies have shown that atherogenic significance of the total cholesterol concentration must be viewed with restrictions. From numerous studies, it is now concluded that LDL is the carrier of 70 percent of total cholesterol and it transpos cholesterol to tissues and thus is most potential ath...
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What is the most common site of an accessory spleen?
Splenunculi- single or multiple accessory spleens MC site: near the hilum of the spleen > behind the tail of the pancreas The remainder are located in the mesocolon, greater omentum or the splenic ligaments. Significance- failure to identify and remove these at the time of splenectomy may give rise to persistent diseas...
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Linitis plastica is a feature of -a) Hiatus herniab) Chronic gastric ulcerc) Lymphoma of stomachd) Diffuse carcinoma stomach
Linitis plastica Involvement of a broad region of the gastric wall or entire stomach by diffuse stomach cancer cause linitis plastica. It is also known as Brinton's disease. The appearance of stomach is like leather bottle. The other cause of linitis plastica are : Lye ingestion     Sarcoidosis              Metastatic...
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The time duration for functioning of corpus luteum after ovulation in a nonpregnant female is:
Following ovulation, the corpus luteum develops from the remains of the dominant or Graafian follicle in a process referred to as luteinization. The human corpus luteum is a transient endocrine organ that, in the absence of pregnancy, will rapidly regress 9 to 11 days after ovulation. Luteolysis results from decreased ...
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Today vaginal sponge failure rate is?
Ans. (b) 9%Ref: Appendix-115 for "METHODS OF CONTRACEPTION"
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True-regarding DNA-replication:
All of the above
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Nipple confusion means?
Ans. (a) Baby fed with a bottle finding it difficult and confusing to suckle at breastRef: OP Ghai 8th ed./153* A problem that may beset a bottlefed baby in which it forgets how to nurse on mother' nipple* Breastfeeding requires far more vigorous mouth and tongue motions and greater muscle coordination than bottlefeedi...
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Enzyme Transketolase requires ?
Transketolase reactions require thiamine pyrophosphate (TPP).Coenzyme can be classified according to the group whose transfer they facilitate.a) For transfer groups other than hydrogen :- Sugar phosphate, CoA-SH, thiamine pyrophosphate (TPP), Pyridoxal phosphate, Folate, Biotin.b) For transfer of hydrogen : - NAD+, NAD...
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What is seen earliest in USG?
Yolk sac is the first anatomic structure seen within gestational sac. By TVS, it can be seen as early as 5.5week By TAS, it is seen by 7 weeks. Ref:Datta Obs 9e pg 601.
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Tennis Racquet cells
Rhabdomyosarcoma An adjectival description for a relatively elongated cell, lesion, structure or radiological density that is globose at one end and elongated at the other, alike to the device used in game of tennis. Tennis racquet cell: A tennis-racquet-shaped variant of rhabdomyoblast seen in sarcoma botryoides, a fo...
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Hidebound disease is:
Systemic Sclerosis: Scleroderma, dermatosclerosis, hidebound disease.
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Patient with head injuries with rapidly increasing intracranial tension without hematoma, the drug of choice for initial management would be:
Mannitol is an osmotic diuretic. It is used for Increased intracranial or intraocular tension (acute congestive glaucoma, head injury, stroke, etc.): by osmotic action, it encourages the movement of water from brain parenchyma, CSF and aqueous humor; The dose is 1-1.5 g/kg is infused over 1 hour as 20% solution to tran...
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Which is derived from thoracolumbar fascia -
Ans. is 'b' i.e., Lateral arcuate ligament o Thoracolumbar fascia covers the deep muscles of back of the trunk, o It is composed of three fascial layers -i) Anterior layer# It is the thinnest layer# Medially it is attached to transverse process of lumbar vertebrae.# Laterally it fuses with fascia transversalis and apon...
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A patient with carcinoma lower 1/3 of oesophagus, receives chemo Radiotherapy and dysphagia shows complete response. What is the next step in management?
- Clinical trials and meta-analyses have shown that a C + surgery regimen could significantly improve the survival of locally advanced esophageal carcinoma patients compared to surgery alone - Endoscopic biopsy, endoscopic ultrasonography, MRI (at various sequences) and PET-CT all had shocomings for evaluating cCR and ...
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Dennie-Morgan fold is seen in -
dennie morgan fold-accentuated grooves or lines below the lower eyelid margins. seen in atopic dermatitis. Ref Harrison20th edition pg 2534
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Stereotactic radiosurgery is used in which of the following conditions?
STEREOTACTIC RADIOSURGERY - SRS is a non-surgical radiation therapy used to treat functional abnormalities & small tumors of brain - Deliver precisely-targeted concentrated dose of radiation in fewer high-dose treatments to a defined volume in the brain Common uses of Stereotactic Radiosurgery (BAT) - Brain tumor(Benig...
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In MVP, you would expect the ejection click to be more accentuated and the murmur to move closer the first hea sound in a patient
Anxiety, with an increase in hea rate or decreasing venous return to the hea (standing), causes the click and murmur to occur earlier in systole (closer to S1). Lying down, squatting, sustained hand grip exercise, or passive leg lifting in the supine position increase venous return and cause the click and murmur to occ...
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Typhoid in first week of illness is best diagnosed by:-
Laboratory diagnosis of typhoid : 'BASU' mnemonic Test of diagnosis Time of diagnosis Remarks Blood culture 1st week Mainstay of diagnosis Antibodies (widal test) 2nd week Moderate sensitivity & specificity Stool culture 3rd week Useful for carries Urine test 4th week Useful for carries
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Prostaglandin causing renal vasodilation:
B i.e. PGE2 Blood vesselsPlateletsBronchiKidneyUterusPGE2VasodilationVariable effectDilatationVasodilatationRenin releaseContractionSoftening of cervix ContractionSoftening of cervixPFF2aVasodilation-Constriction-PGI2VasodilationAntiaggregatoryDilatationVasodilationRenin release?TXA2VasoconstrictionAggregationConstrict...
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Cerberus is associated with development of:
The cells in the hypoblast (endoderm) at the cephalic margin of the disc form the anterior visceral endoderm, which expresses head forming genes, including OTX2, LIM1, and HESX1 and the secreted factor Cerberus. Ref: Langman's embryology 11th edition Chapter 5.
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Acute onset of cough, stridor and respiratory distress in the absence of fever is suggestive of:
Ans. A. Foreign bodyImmediate symptoms of foreign body inhalation include choking, coughing, increasing respiratory distress or difficulty in speaking.
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Erythropoietin in kidney is secreted by
Interstitial cells in paritubular capillaries releoses erythroportin in responce to hypoxia.
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What is the reason for Thyroid Storm after Total Thyroidectomy?
Ans. (b) Due to Inadequate Preparation of PatientRef: Surgery Sixer 3rd Edition 229* It is a condition of hyperthyroidism accompanied by fever, central nervous system agitation or depression, cardiovascular dysfunction that may be precipitated by infection, surgery or trauma and occasionally by amiodarone administratio...
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'Alien limb' is characteristically seen in:
Coicobasal degeneration (CBD) is a slowly progressive dementing illness associated with severe gliosis and neuronal loss in both the coex and basal ganglia. CBD with unilateral onset presents with rigidity, dystonia, and apraxia of one arm and hand, sometimes called the alien limb when it begins to exhibit unintended m...
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Baby 20 year old female complains of sudden onset palpitation and apprehension. She is sweating for last 10 minutes and fears of impending death. Diagnosis is -
The information in this question are: - 1) Sudden (abrupt) onset, 2) Palpitation, 3) Apprehension, 4) Sweating, 5) Sense of impending doom, 6) Symptoms lasts for few minutes (10 minutes). These are the features of panic disorder.
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Which of the following is not caused by over expression of a trinucleotide repeat?
Ans: a (Alzheimer's disease) Ref: Ganong, 22nd ed, p. 215Alzheimer's disease is not caused by over expression of a trinucleotide repeat. The rest 3 options are examples of trinucleotide repeat diseases where as Alzheimer's is primarly a degenerative disease (Basal ganglia) resulting in movement disorder.Some examples o...
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Irreversible dementia is caused due to:
Vascular dementia is a cause of progressive dementia due to impaired blood supply to the brain.
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A 64-year-old man, who is a chronic alcoholic, presents with fever, chills and increasing shoness of breath. The patient appears in acute respiratory distress and complains of pleuritic chest pain. Physical examination shows crackles and decreased breath sounds over both lung fields. The patient exhibits tachypnea, wit...
Klebsiella pneumoniae is the most frequent cause of gram-negative bacterial pneumonia. It commonly afflicts debilitated and malnourished people, paicularly chronic alcoholics. Thick, mucoid (often blood-tinged) sputum is characteristic because the organism produces an abundant viscid capsular polysac-charide, which the...
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The protein synthesis site of the cell body of neurons
The nissl bodies are the protein synthesis site in a neuron They are equivalent to rough endoplasmic reticulum Ref:Guyton and Hall textbook of medical physiology 12th edition ,page number 676
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Bounderies of anatomical snuff box are all except
Ans. is 'd' i.e., ECU Anatomical Snuffbox Triangular depression on the dorsal and radial aspect of the hand become visible when thumb is fully extended. Boundaries Medial/Posterior - Tendon of the extensor pollicis longus. Lateral/Anterior - Tendon of the extensor pollicis brevis and abductor pollicis longus. Roof Skin...
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Endemicity of a disease means:
Endemic Is the constant presence of a disease agent in a defined geographical area ; refers to 'usual or expected frequency' of a disease in a population. For instance, common cold is endemic because somebody always has one. Endemic diseases in India are : Measles, mumps, rubella, chicken pox, peussis, TB, HIV, Cancers...
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Sulfasalzine is used in: March 2011
Ans. C: Ulcerative Colitis The mainstay of drug therapy for mild and moderate ulcerative colitis is sulfasalazine and other aminosalicylic acid (ASA) compounds and coicosteroids Sulfasalazine It is a sulfa drug, a derivative of mesalazine (also called 5-aminosalicylic acid, or 5-ASA) Sulfasalazine is used in the treatm...
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True about sentinel surveillance is: March 2011
Ans. B: Supplements routine notification Sentinel surveillance helps in supplementing notified cases (those given through routine surveillance system- passive and active) Sentinel surveillance It is the collection and analysis of data by designated institutions selected for their geographic location, medical specialty,...
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Paget's disease of the nipple is
Paget's disease of the nipple is superficial manifestation of an intraductal breast carcinoma. The malignancy spreads within the duct up to the skin of the nipple and down into the substance of the breast. It mimics eczema of nipple and areola. In Paget's disease, there is a hard nodule just underneath the areola, whic...
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One of the following disorders is due to maternal disomy
ref Robbins 9/e p173 Matetnal disomy is associated with disorders like prader Willi syndrome, angelman syndrome.
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Continuous murmur is seen in all the following except:
Answer is D (Peripheral Pulmonary Stenosis) The 'num:11r of pglmonary stenosis is harsh systolic ejection murmur typically preceded by a systolic ejection sound. It is not a continuous murmur. Continuous murmurs result from continuous flow between a high pressure and low pressure area that persists through the end of s...
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Looser's zones is seen in – a) Osteoporosis b) Hyperparathyrodismc) Osteomalacia d) Renal osteodystrophye) Paget's disease
Looser's zone or pseudofracture is pathognomonic for osteomalacia, However, it may occur rarely also in Paget's disease, Fibrous dysplasia, Hyperparathyroidism, Renal osteodystrophy, Hyperphosphatasia, and osteogenesis imperfecta.
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Acquired blue blindness is a feature of
Acquired Colour Blindness Acquired blue colour defect (blue blindness) : It may occur in old age due to increased sclerosis of the crystalline lens. It is owing to the physical absorption of the blue rays by the increased a.ambercoloured pigment in the nucleus. Ref:- A K KHURANA; pg num:-305
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Most common cause for meningitis in adults: September 2009
Ans. D: Streptococcus pneumoniae Streptococcus pneumoniae is the most common cause of meningitis in adults of age over twenty years, accounting for nearly half of the cases. N. meningitidis accounts for nearly 25% of the cases. Staph.aureus and coagulase negative staphylococci are impoant causes of meningitis that occu...
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False statement about post-dural puncture headache (PDPH):
Post Dural puncture Headache Pathophysiology - CSF leak - ICP |es - Traction on nerve fibres originating from piamater Site - Occipital > Frontal > Retrorbital Duration - 7-10 days Pathognomic sign - Change in posture aggravates headache Predisposing conditions - Dura cutting needle (spinal needle)* Most commonly seen ...
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