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RFA strongly modulates the immune system and anti-tumor immune responses in metastatic liver patients. | Radiofrequency tumor ablation (RFA) is a therapeutic modality for liver cancer patients inducing localized tumor necrosis with maximal preservation of normal liver parenchyma. We investigated the immunomodulatory effects exerted by RFA treatment in liver cancer patients with metastatic liver lesions (13 patients) or he... | ['Aged', 'Amino Acid Sequence', 'Carcinoma, Hepatocellular', 'Catheter Ablation', 'Female', 'Humans', 'Immune System', 'Liver Extracts', 'Liver Neoplasms', 'Male', 'Medical Oncology', 'Middle Aged', 'Molecular Sequence Data', 'Neoplasm Metastasis', 'Neoplasms'] | 18,202,772 | [['M01.060.116.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E02.808.750.500', 'E04.014.760.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A15.382'], ['D20.777.351'], ['C04.588.274.623', 'C06.301.623', 'C06.552.6... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Borderline Glenoid Bone Defect in Anterior Shoulder Instability: Latarjet Procedure Versus Bankart Repair. | BACKGROUND: The optimal procedure for anterior shoulder instability with a borderline (15%-20%) bone defect on the anterior rim of the glenoid is still controversial.PURPOSE: To compare the clinical outcome and recurrence rate between the arthroscopic Bankart repair and Latarjet procedure among patients with recurrent ... | ['Adolescent', 'Adult', 'Arthroplasty', 'Arthroscopy', 'Cohort Studies', 'Female', 'Glenoid Cavity', 'Humans', 'Joint Instability', 'Male', 'Middle Aged', 'Range of Motion, Articular', 'Shoulder Dislocation', 'Young Adult'] | 29,879,363 | [['M01.060.057'], ['M01.060.116'], ['E04.555.110', 'E04.680.101'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['A02.835.232.087.783.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['M01.060.116.630'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunohistochemical study on human atrial natriuretic polypeptide in the ventricle of hearts with endocardial fibroelastosis. | The presence and distribution of human atrial natriuretic polypeptide (ANP) were investigated immunohistochemically in the ventricles of hearts of 14 cases with endocardial fibroelastosis and 15 cases with noncardiac disease in children. Paraffin sections of autopsied hearts with endocardial fibroelastosis were stained... | ['Atrial Natriuretic Factor', 'Child', 'Endocardial Fibroelastosis', 'Humans', 'Immunoenzyme Techniques', 'Infant, Newborn', 'Myocardium'] | 2,151,366 | [['D06.472.699.584.500', 'D12.644.548.585.500'], ['M01.060.406'], ['C14.280.238.281'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['M01.060.703.520'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pilot data of a brief veteran peer intervention and its relationship to mental health treatment engagement. | Underutilization of mental health care is a significant problem among veterans. Offering peer support may improve mental health care engagement. This observational pilot study was conducted using an institutional review board-approved data repository to preliminarily evaluate the association and potential impact of a c... | ['Adult', 'Ambulatory Care', 'Behavior Therapy', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Mental Health Services', 'Patient Acceptance of Health Care', 'Patient Satisfaction', 'Peer Group', 'Pilot Projects', 'Veterans'] | 28,493,731 | [['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['F04.754.137'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F04.408', 'N02.421.461'], ['F01.100.150.750.500', 'F01.145.488.887.500', 'N05.300.150.800.500'], ['F01.100.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reference Charts for Fetal Cerebellar Vermis Height: A Prospective Cross-Sectional Study of 10605 Fetuses. | OBJECTIVE: To establish reference charts for fetal cerebellar vermis height in an unselected population.METHODS: A prospective cross-sectional study between September 2009 and December 2014 was carried out at ALTAMEDICA Fetal-Maternal Medical Centre, Rome, Italy. Of 25203 fetal biometric measurements, 12167 (48%) measu... | ['Adult', 'Cerebellar Vermis', 'Cross-Sectional Studies', 'Female', 'Fetus', 'Gestational Age', 'Humans', 'Pregnancy', 'Prospective Studies', 'Reference Values', 'Regression Analysis', 'Ultrasonography, Prenatal'] | 26,812,238 | [['M01.060.116'], ['A08.186.211.132.810.428.200.212.299'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.65... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Resistance of a subset of red blood cells to clearance by antibodies in a mouse model of incompatible transfusion. | BACKGROUND: Alloimmunization to antigens on transfused red blood cells (RBCs) represents a major barrier to chronic transfusion. In extreme cases of multiple alloimmunization, clinicians may be faced with the decision of transfusing incompatible RBCs or risking death from lack of transfusion. The disastrous results of ... | ['Animals', 'Antigen-Antibody Reactions', 'Antigens, Heterophile', 'Blood Group Incompatibility', 'Cell Survival', 'Complement System Proteins', 'Disease Models, Animal', 'Erythrocytes', 'Female', 'Glycophorins', 'Humans', 'Isoantibodies', 'Isoantigens', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Phagocyt... | 23,033,973 | [['B01.050'], ['G12.122'], ['D23.050.244'], ['G09.188.114', 'G12.186'], ['G04.346'], ['D12.776.124.486.274'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D12.644.233.800.350', 'D12.776.395.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The E-hook of tubulin interacts with kinesin's head to increase processivity and speed. | Kinesins are dimeric motor proteins that move processively along microtubules. It has been proposed that the processivity of conventional kinesins is increased by electrostatic interactions between the positively charged neck of the motor and the negatively charged C-terminus of tubulin (E-hook). In this report we chal... | ['Adenosine Diphosphate', 'Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Animals', 'Binding Sites', 'Biophysics', 'Biotinylation', 'Blotting, Western', 'Brain', 'Cattle', 'Chromatography, Ion Exchange', 'Cloning, Molecular', 'Dimerization', 'Dose-Response Relationship, Drug', 'Electrophoresis, Polyacrylamide G... | 16,100,283 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['G02.111.570.120'], ['H01.158.344', 'H01.671.100'], ['E05.601.085', 'G02.111.109', 'G03.162'], ['E05.196.401.143', 'E05.30... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Subarachnoid morphine versus TAP blocks for enhanced recovery after caesarean section delivery: A randomized controlled trial. | INTRODUCTION: Subarachnoid morphine is widely used for pain relief in enhanced recovery program after cesarean section in spite of its side effects. However, the role of TAP block is still controversial. The aim of our study was to compare the impact of these analgesic techniques (subarachnoid morphine and TAP block) o... | ['Abdominal Muscles', 'Adult', 'Analgesics, Opioid', 'Anesthesia Recovery Period', 'Anesthesia, Obstetrical', 'Anesthesia, Spinal', 'Cesarean Section', 'Early Ambulation', 'Female', 'Humans', 'Morphine', 'Nerve Block', 'Pain Measurement', 'Pain, Postoperative', 'Pregnancy', 'Ultrasonography, Interventional', 'Walking'] | 27,080,379 | [['A02.633.567.050'], ['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E03.160', 'E04.614.750.055', 'N02.421.585.753.750.055'], ['E03.155.364'], ['E03.155.086.331'], ['E04.520.252.500'], ['E02.760.169.063.500.335', 'E02.831.... | ['Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Myogenic and scalp signals evoked by midinspiratory airway occlusion. | A somatosensory potential that is evoked by transient added inspiratory load has previously been described (Davenport PW, Friedman WA, Thompson FJ, and Franzen O. J Appl Physiol 60: 1843-1848, 1986). This evoked potential is novel because it arises in response to a stimulus that also evokes a muscle response, and so th... | ['Adult', 'Airway Obstruction', 'Electromyography', 'Electrooculography', 'Evoked Potentials, Somatosensory', 'Female', 'Humans', 'Male', 'Masseter Muscle', 'Respiratory Mechanics', 'Scalp'] | 10,926,622 | [['M01.060.116'], ['C08.618.846.185'], ['E01.370.405.255', 'E01.370.530.255'], ['E01.370.380.230.285', 'E01.370.405.245.787.285'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567.600.500', 'A14.530.630'], ['G09.772.705.700'], ['A01.456.810']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Development of an efficient method for the preparative isolation and purification of chlorophyll a from a marine dinoflagellate Amphidinium carterae by high-speed counter-current chromatography coupled with reversed-phase high-performance liquid chromatography. | In our research into chlorophylls of marine dinoflagellates, chlorophyll a was separated rapidly from the hexane extract of Amphidinium carterae in three steps. The first step was silica gel column chromatography, where elution was performed with 0-50% ethyl acetate in n-hexane. The second was high-speed counter-curren... | ['Animals', 'Chlorophyll', 'Chromatography, Liquid', 'Dinoflagellida'] | 17,053,914 | [['B01.050'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['E05.196.181.400'], ['B01.043.214']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Depth-dependent mechanical properties of enamel by nanoindentation. | Nanoindentation has recently emerged to be the primary method to study the mechanical behavior and reliability of human enamel. Its hardness and elastic modulus were generally reported as average values with standard deviations that were calculated from the results of multiple nanoindentation testing. In such an approa... | ['Compressive Strength', 'Dental Enamel', 'Elasticity', 'Hardness', 'Hardness Tests', 'Humans'] | 17,109,413 | [['G01.374.180'], ['A14.549.167.900.255'], ['G01.374.590'], ['G01.374.647'], ['E05.417', 'E05.570.500.500', 'G01.374.647.457', 'G01.374.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Invasion of Haemophilus influenzae and Pseudomonas aeruginosa in humans. | Levels of serum IgG antibodies to somatic antigens of Haemophilus influenzae and Pseudomonas aeruginosa were determined in 127 healthy people, 37 patients with chronic bronchitis and 20 patients with bronchiectasis by enzyme-linked immunosorbent assay. The logarithmic mean titers of antibodies to Haemophilus influenzae... | ['Adult', 'Aged', 'Antibodies, Bacterial', 'Bronchiectasis', 'Bronchitis', 'Haemophilus Infections', 'Haemophilus influenzae', 'Humans', 'Middle Aged', 'Pseudomonas Infections', 'Pseudomonas aeruginosa'] | 3,927,515 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['C08.127.384'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['C01.150.252.400.700.433'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gemcitabine-based combination chemotherapy followed by radiation with capecitabine as adjuvant therapy for resected pancreas cancer. | PURPOSE: To report outcomes for patients with resected pancreas cancer treated with an adjuvant regimen consisting of gemcitabine-based combination chemotherapy followed by capecitabine and radiation.PATIENTS AND METHODS: We performed a retrospective review of a series of patients treated at a single institution with a... | ['Adenocarcinoma', 'Adult', 'Aged', 'Analysis of Variance', 'Antineoplastic Combined Chemotherapy Protocols', 'Capecitabine', 'Chemotherapy, Adjuvant', 'Cisplatin', 'Deoxycytidine', 'Disease-Free Survival', 'Drug Administration Schedule', 'Female', 'Fluorouracil', 'Humans', 'Karnofsky Performance Status', 'Male', 'Midd... | 19,409,732 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['E02.186.170', ... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparative serum proteome analysis reveals potential early pregnancy-specific protein biomarkers in pigs. | In this study, the comparative serum proteome profile of Day 5, 12 and 16 of gestation, representing three early embryonic events, namely formation, elongation and implantation of blastocysts, and non-pregnant control were explored by a label-free quantitation-based mass spectrometric approach to identify early pregnan... | ['Animals', 'Biomarkers', 'Female', 'Pregnancy', 'Pregnancy Proteins', 'Pregnancy, Animal', 'Proteome', 'Proteomics', 'Swine'] | 30,418,869 | [['B01.050'], ['D23.101'], ['G08.686.784.769'], ['D12.776.780'], ['G08.686.784.769.498'], ['D12.776.817'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The Effect of Pyrroloquinoline Quinone on Apoptosis and Autophagy in Traumatic Brain Injury. | BACKGROUND: Pyrroloquinoline quinone is an anionic, water-soluble compound with antioxidant characteristic. The role of pyrroloquinoline quinone in pharmacology and nutrition has attracted wide attention of researchers. Although a few experiments have confirmed that pyrroloquinoline quinone plays an obvious effective r... | ['Animals', 'Animals, Newborn', 'Apoptosis', 'Astrocytes', 'Autophagosomes', 'Autophagy', 'Brain Injuries, Traumatic', 'Caspase 3', 'Cells, Cultured', 'Disease Models, Animal', 'Glial Fibrillary Acidic Protein', 'Glutamic Acid', 'L-Lactate Dehydrogenase', 'Lysosomal-Associated Membrane Protein 2', 'Male', 'Microtubule-... | 28,124,619 | [['B01.050'], ['B01.050.050.282'], ['G04.146.954.035'], ['A08.637.200', 'A11.650.200'], ['A11.284.430.214.190.875.190.700.500'], ['G04.011'], ['C10.228.140.199.444', 'C10.900.300.087.235', 'C26.915.300.200.194'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outcomes of Recurrent Retinal Detachment Surgery following Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment. | AIM: To study the anatomical and functional outcomes of recurrent retinal detachment (RD) surgery following pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment.METHODS: Retrospective analysis of 133 consecutive cases of recurrent RD.INCLUSION CRITERIA: age ?18 years, recurrent RD following PPV ± encirclin... | ['Endotamponade', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Recurrence', 'Reoperation', 'Retina', 'Retinal Detachment', 'Retrospective Studies', 'Risk Factors', 'Treatment Outcome', 'Visual Acuity', 'Vitrectomy'] | 29,125,779 | [['E02.520.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['C23.550.291.937'], ['E04.690'], ['A09.371.729'], ['C11.768.648'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of VKORC1, CYP2C9, CFP4F2, and GGCX Gene Polymorphisms on Warfarin Dose in Japanese Pediatric Patients. | BACKGROUND: Warfarin dosage requirements show considerable inter-individual variability. There are some reports of warfarin dose regimens correlating with single nucleotide polymorphisms (SNP) for CYP2C9, VKORC1 and other genes in adults. In children, however, reports are scarcer than in adults and the number of genes ... | ['Adolescent', 'Adult', 'Alleles', 'Anticoagulants', 'Asian Continental Ancestry Group', 'Child', 'Child, Preschool', 'Cytochrome P-450 CYP2C9', 'Cytochrome P450 Family 4', 'Drug Therapy, Combination', 'Female', 'Genotype', 'Humans', 'Infant', 'Japan', 'Male', 'Pharmacogenomic Variants', 'Polymorphism, Single Nucleotid... | 27,262,824 | [['M01.060.057'], ['M01.060.116'], ['G05.360.340.024.340.030'], ['D27.505.954.502.119'], ['M01.686.508.200'], ['M01.060.406'], ['M01.060.406.448'], ['D08.244.453.491.500.500', 'D08.811.682.690.708.170.450.500.500', 'D12.776.422.220.453.491.500.500'], ['D08.244.453.870', 'D08.811.682.690.708.170.496', 'D12.776.422.220.4... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Breakdown of lysosomal glycogen in cultured fibroblasts from glycogenosis type II patients after uptake of acid alpha-glucosidase. | Fibroblast cultures from patients with different clinical subtypes of glycogenosis type II were compared with respect to residual acid alpha-glucosidase activity and lysosomal glycogen content. Lysosomal glycogen storage was most pronounced in fibroblasts from patients with the rapidly progressive infantile form of the... | ['Cell Fractionation', 'Cell Line', 'Fibroblasts', 'Glycogen', 'Glycogen Storage Disease', 'Glycogen Storage Disease Type II', 'Humans', 'Lysosomes', 'Proteins', 'alpha-Glucosidases'] | 3,302,116 | [['E05.242.251'], ['A11.251.210'], ['A11.329.228'], ['D05.750.078.562.388', 'D09.698.365.388'], ['C16.320.565.202.449', 'C18.452.648.202.449'], ['C10.228.140.163.100.435.340', 'C16.320.565.189.435.340', 'C16.320.565.202.449.500', 'C16.320.565.595.554.340', 'C18.452.132.100.435.340', 'C18.452.648.189.435.340', 'C18.452.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thyroid hormone response elements in pituitary genes. | Thyroid hormones regulate the transcription of a number of genes in the anterior pituitary gland. A thyroid hormone response element in the regulatory region of the rat growth hormone gene has previously been shown to mediate the effects of thyroid hormones on growth hormone gene transcription. The 5' flanking regions ... | ['Animals', 'Blotting, Southern', 'DNA', 'Glycoprotein Hormones, alpha Subunit', 'Growth Hormone', 'Humans', 'Oligonucleotide Probes', 'Pituitary Hormones, Anterior', 'Prolactin', 'Regulatory Sequences, Nucleic Acid', 'Thyroid Hormones', 'Thyrotropin'] | 2,472,172 | [['B01.050'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['D13.444.308'], ['D06.472.699.322.326.562', 'D06.472.699.322.576.288.750', 'D06.472.699.322.576.463.249', 'D06.472.699.631.525.343.288.750', 'D06.472.699.631.525.343.463.249', 'D06.472.699.631.525.883.249', 'D06.472.699.649.367.562', 'D12.644.548.691... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk factors for acute cholecystitis and for intraoperative complications. | BACKGROUND: Acute cholecystitis is still frequent in emergency surgical departments. As surgical technique, nowadays laparoscopy is widely used and with low complications and with low postoperative morbidity.MATERIAL AND METHODS: We perform an analytical study about the safety of laparoscopic surgery in patients with a... | ['Adult', 'Aged', 'Blood Loss, Surgical', 'Body Mass Index', 'Cholecystectomy', 'Cholecystectomy, Laparoscopic', 'Cholecystitis, Acute', 'Conversion to Open Surgery', 'Female', 'Humans', 'Intraoperative Complications', 'Lithiasis', 'Male', 'Middle Aged', 'Obesity', 'Retrospective Studies', 'Risk Factors', 'Romania', 'T... | 29,068,324 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.414.300', 'C23.550.505.300'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E04.210.120.172'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['C06.130.564.263.500'], ['E04.502.250.155'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Vibrant Soundbridge®: An Alternative Hearing System for Preschool Children with Aural Atresia]. | BACKGROUND: The audiological treatment of children with aural atresia makes high demands on physicians and acousticians. Conventional hearing systems are often not tolerated by children and therefore do not meet the needs of the early and efficient therapy of hearing disorders. Aim of the present study was the evaluati... | ['Audiometry, Pure-Tone', 'Child, Preschool', 'Ear', 'Hearing Aids', 'Hearing Loss, Conductive', 'Humans', 'Infant', 'Ossicular Prosthesis', 'Quality of Life', 'Treatment Outcome'] | 27,626,815 | [['E01.370.382.375.060.055'], ['M01.060.406.448'], ['A01.456.313', 'A09.246'], ['E07.305.906.500', 'E07.814.458'], ['C09.218.458.341.562', 'C10.597.751.418.341.562', 'C23.888.592.763.393.341.562'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E07.695.550'], ['I01.800', 'K01.752.400.750', 'N06.850... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
TRPV1 is a Responding Channel for Acupuncture Manipulation in Mice Peripheral and Central Nerve System. | BACKGROUND/AIMS: Acupuncture involves inserting a fine needle into a specific point, often called an acupoint, thereby initiating a therapeutic effect accompanied by phenomena such as soreness, heaviness, fullness, and numbness. Acupoints are characterized as points located in deep tissues with abundant sensory nerve t... | ['Acupuncture', 'Animals', 'Calcium-Calmodulin-Dependent Protein Kinase Type 2', 'Central Nervous System', 'Electroacupuncture', 'Extracellular Signal-Regulated MAP Kinases', 'Ganglia, Spinal', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Phosphorylation', 'Receptors, N-Methyl-D-Aspartate', 'Signal Transduc... | 30,231,245 | [['H02.004'], ['B01.050'], ['D08.811.913.696.620.682.700.125.200', 'D12.644.360.100.200', 'D12.776.476.100.200'], ['A08.186'], ['E02.186.250', 'E02.190.044.244', 'E02.331.399', 'E02.779.468.399', 'E02.831.535.468.399', 'E03.091.823.500', 'E03.155.519'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D1... | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A case of Wegener's granulomatosis presenting with jaw claudication. | The major manifestations of Wegener's granulomatosis have been well described. Jaw claudication has not been recognized as one of the symptoms associated with this disease. We report the first case of Wegener's granulomatosis presenting with jaw claudication. Documentation of different histological types of vasculitis ... | ['Diagnosis, Differential', 'Giant Cell Arteritis', 'Granulomatosis with Polyangiitis', 'Humans', 'Intermittent Claudication', 'Male', 'Mandibular Diseases', 'Middle Aged'] | 6,512,795 | [['E01.171'], ['C10.114.875.700', 'C10.228.140.300.850.500', 'C14.907.253.946.700', 'C14.907.940.090.530', 'C14.907.940.907.700', 'C17.800.862.252', 'C20.111.258.962.800'], ['C08.381.483.950', 'C14.907.940.897.249.750', 'C20.111.193.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.137.126.669', 'C23.88... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of colonic dendritic cells in normal and colitic mice. | AIM: Recent studies demonstrating the direct involvement of dendritic cells (DC) in the activation of pathogenic T cells in animal models of inflammatory bowel disease identify DC as important antigen presenting cells in the colon. However, very little is known about the properties of colonic DC.METHODS: Using immunohi... | ['Animals', 'Colitis', 'Colon', 'Dendritic Cells', 'Interleukin-2', 'Macrophages', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Phenotype', 'T-Lymphocytes'] | 16,419,163 | [['B01.050'], ['C06.405.205.265', 'C06.405.469.158.188'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.155', 'D23.529.374... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First collection records of Aedes japonicus in Minnesota. | Aedes japonicus was first identified in the eastern United States during 1998 and has since spread to locations west of the Mississippi River. This species was found in Minnesota for the first time during 2007 at a tire recycling facility in Scott County and was identified during 2008 at 43 locations in 4 additional Mi... | ['Aedes', 'Animals', 'Demography', 'Larva', 'Minnesota', 'Time Factors'] | 19,852,229 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B05.500.500', 'G07.345.500.550.500.500'], ['Z01.107.567.875.350.510', 'Z01.107.567.875.510.510'], ['G01.910.857']] | ['Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Cortical thickness and subcortical structure volume abnormalities in patients with major depression with and without anxious symptoms. | BACKGROUND: Anxious depression is one of the common subtypes of major depressive disorder (MDD). Clinically, patients with anxious depression exhibit more severe depressive symptoms than patients with nonanxious depression. The aim of the present study was to explore the common and differing cortical and subcortical st... | ['Adult', 'Anxiety', 'Caudate Nucleus', 'Cerebral Cortex', 'Depression', 'Depressive Disorder, Major', 'Diagnostic and Statistical Manual of Mental Disorders', 'Female', 'Hippocampus', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Organ Size', 'Statistics as Topic'] | 28,828,215 | [['M01.060.116'], ['F01.470.132'], ['A08.186.211.200.885.287.249.487.550.184'], ['A08.186.211.200.885.287.500'], ['F01.145.126.350'], ['F03.600.300.375'], ['L01.453.245.945.200'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Brain-derived neurotrophic factor inhibits phenylalanine-induced neuronal apoptosis by preventing RhoA pathway activation. | Phenylketonuria (PKU) is neuropathologically characterized by neuronal cell loss, white matter abnormalities, dendritic simplification, and synaptic density reduction. The neuropathological effect may be due to the 'toxicity' of the high concentration of phenylalanine, while little is known about the related treatments... | ['Animals', 'Apoptosis', 'Biotransformation', 'Blotting, Western', 'Brain-Derived Neurotrophic Factor', 'Cells, Cultured', 'Cytosol', 'GTP Phosphohydrolases', 'In Situ Nick-End Labeling', 'Mitochondria', 'Myosin Light Chains', 'Neurons', 'Phenylalanine', 'Phosphorylation', 'RNA Interference', 'Rats', 'Rats, Sprague-Daw... | 19,890,711 | [['B01.050'], ['G04.146.954.035'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['A11.251'], ['A11.284.430.214.200', 'A11.284.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HOUSE FINCH ( HAEMORHOUS MEXICANUS)-ASSOCIATED MYCOPLASMA GALLISEPTICUM IDENTIFIED IN LESSER GOLDFINCH ( SPINUS PSALTRIA) AND WESTERN SCRUB JAY ( APHELOCOMA CALIFORNICA) USING STRAIN-SPECIFIC QUANTITATIVE PCR. | : In 1994 Mycoplasma gallisepticum was found to be the etiologic agent of House Finch ( Haemorhous mexicanus) conjunctivitis, a rapidly expanding epidemic caused by a genetically discrete, House Finch-associated strain of M. gallisepticum (HFMG). While most prominent in House Finches, HFMG has been reported in other m... | ['Animals', 'Bird Diseases', 'DNA, Bacterial', 'Mycoplasma Infections', 'Mycoplasma gallisepticum', 'Passeriformes', 'Polymerase Chain Reaction'] | 29,053,429 | [['B01.050'], ['C22.131'], ['D13.444.308.212'], ['C01.150.252.400.610.610'], ['B03.440.860.580.553.553.345'], ['B01.050.150.900.248.620'], ['E05.393.620.500']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Lymphatic metastasis and cell adhesion, growth and growth inhibition]. | Malignant tumor cells often metastasize to regional and distant lymph nodes. The mechanisms of lymphatic metastasis, however, have not been well understood. To investigate these mechanisms, we used mouse CS-21 malignant T lymphoma cells which form tumors at subcutaneous sites and metastasize to lymph nodes with a high ... | ['Animals', 'Antibodies, Monoclonal', 'Apoptosis', 'Cell Adhesion', 'Cell Death', 'Cell Division', 'Lymph Nodes', 'Lymphatic Metastasis', 'Lymphoma, T-Cell', 'Mice', 'Tumor Cells, Cultured'] | 8,439,186 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.146.954.035'], ['G04.022'], ['G04.146'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.697.650.560', 'C23.550.727.650.560'], ['C04.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Has nicotine a local anaesthetic action? | In this study, we investigated whether nicotine may have a local anaesthetic action in mice, using the tail press and tail immersion tests. Nicotine increased the latent time of biting the clip in the tail press test (p < 0.001) and retarded tail withdrawal latency in the tail immersion test (p < 0.01), compared to con... | ['Anesthetics, Local', 'Animals', 'Female', 'Immersion', 'Male', 'Mecamylamine', 'Mice', 'Nicotine', 'Nicotinic Antagonists', 'Pain Measurement', 'Plants, Toxic', 'Prilocaine', 'Tobacco, Smokeless'] | 8,736,044 | [['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['B01.050'], ['E05.466'], ['D02.455.426.100.080.550.500', 'D04.075.080.500.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.132.760.570', 'D03.383.725.518'], ['D27.505.519.625.120.200.700', 'D27.505.696.577.120.200.700'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Persistence and degradation of maize-expressed vaccine protein, Escherichia coli heat-labile enterotoxin subunit B, in soil and water. | Transgenic plants represent an innovative platform for the cost-effective large-scale production of various pharmaceutical proteins. The eventual open-field production of plant-made pharmaceuticals (PMPs) requires risk assessment to determine the potential for harm to the surrounding ecosystem. In the present study, th... | ['Enterotoxins', 'Escherichia coli', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Plants, Genetically Modified', 'Protein Subunits', 'Soil', 'Vaccines', 'Vibrio cholerae', 'Water', 'Zea mays'] | 18,198,938 | [['D23.946.330'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.300'], ['B01.650.520', 'B05.620.600'], ['D12.776.813'], ['D20.721', 'G01.311.820', 'G16.500.275.815', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-êB signaling. | Beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC) is crucial for the degradation of IêBá. Our previous transcriptome sequencing analysis revealed that tetraspanin 15 (TSPAN15) was significantly upregulated in clinical oesophageal squamous cell carcinoma (OSCC) tissues. Here, we show that high TSPAN15... | ['Aged', 'Animals', 'Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Chemokine CCL2', 'Esophageal Neoplasms', 'Esophageal Squamous Cell Carcinoma', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Intercellular Adhesion Molecule-1', 'Lymphatic Metastasis', 'Male', 'Matrix Metalloproteinase 9', 'Mice', 'Mi... | 29,650,964 | [['M01.060.116.100'], ['B01.050'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['C04.588.274.476.205', 'C04.588.443.353... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Polyphenolic profile characterization of Agrimonia eupatoria L. by HPLC with different detection devices. | Liquid chromatography coupled to diode array and electrospray ionization mass spectrometry detection was used to establish the polyphenolic profile of an ethyl acetate fraction from Agrimonia eupatoria L. aqueous-alcoholic extract. Additionally, an HPLC technique with post-column derivatization by p-dimethylaminocinnam... | ['Agrimonia', 'Antioxidants', 'Chromatography, High Pressure Liquid', 'Flavonoids', 'Phenols', 'Polyphenols', 'Spectrometry, Mass, Electrospray Ionization', 'Spectrophotometry, Ultraviolet'] | 15,981,197 | [['B01.650.940.800.575.912.250.859.937.500.033'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E05.196.181.400.300'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D02.455.426.559.389.657'], ['D02.455.426.559.389.657.715', 'D03.633.100.150.266.450.260.777'], ['E05.196.566.600'], ['E05.19... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dipeptidyl peptidase-4 inhibition with linagliptin prevents western diet-induced vascular abnormalities in female mice. | BACKGROUND: Vascular stiffening, a risk factor for cardiovascular disease, is accelerated, particularly in women with obesity and type 2 diabetes. Preclinical evidence suggests that dipeptidylpeptidase-4 (DPP-4) inhibitors may have cardiovascular benefits independent of glycemic lowering effects. Recent studies show th... | ['Animals', 'Aorta', 'Diet, Western', 'Dipeptidyl-Peptidase IV Inhibitors', 'Endothelial Cells', 'Female', 'Hypoglycemic Agents', 'Linagliptin', 'Mice, Inbred C57BL', 'Obesity', 'Pulse Wave Analysis', 'Vascular Remodeling', 'Vascular Stiffness', 'Vasodilation'] | 27,391,040 | [['B01.050'], ['A07.015.114.056'], ['G07.203.650.240.310'], ['D27.505.519.389.745.335', 'D27.505.696.422.500'], ['A11.436.275'], ['D27.505.696.422'], ['D03.633.100.759.562', 'D03.633.100.786.563'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['C18.654.726.500', 'C23.888.144.699.5... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Parallel, interdependent channels for location and orientation in sensorimotor transformations for reaching and grasping. | 1. Subjects were presented with a cylinder, whose orientation with respect to the vertical and location in space varied from trial to trial. They grasped a similar cylinder in their hands and were instructed to align the grasped cylinder with the target cylinder. In some experiments the task was performed from memory, ... | ['Attention', 'Humans', 'Kinesthesis', 'Mental Recall', 'Orientation', 'Posture', 'Proprioception', 'Psychomotor Performance', 'Psychophysics'] | 8,229,163 | [['F02.830.104.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.541.504', 'G11.561.790.541.587'], ['F02.463.425.540.641'], ['F01.058.577', 'F02.830.606'], ['G11.427.695'], ['F02.830.816.541', 'G07.888.750', 'G11.561.790.541'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E01.370.685', 'F04.096.753'... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biosynthetic alr alanine racemase from Salmonella typhimurium: DNA and protein sequence determination. | The nucleotide sequence of the alr gene encoding the biosynthetic alanine racemase in Salmonella typhimurium is reported. The sequence was determined by the dideoxy chain termination method of Sanger mostly from recombinants derived from shotgun and specific subcloning of a 2.6-kilobase region containing the alr gene. ... | ['Alanine Racemase', 'Amino Acid Isomerases', 'Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'Codon', 'DNA, Bacterial', 'Genes', 'Genes, Bacterial', 'Plasmids', 'Protein Biosynthesis', 'Salmonella typhimurium'] | 3,524,676 | [['D08.811.399.894.200.200'], ['D08.811.399.894.200'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D13.444.308.212'], ['G05.360.340.024.340'], ['G05.360.340.024.340.36... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Novel histone deacetylase inhibitors derived from Magnolia officinalis significantly enhance TRAIL-induced apoptosis in non-small cell lung cancer. | Histone modifications play critical roles in the progression of non-small cell lung cancer (NSCLC), which accounts for almost 85% of all diagnosed lung cancers. Magnolol and polyphenol mixture (PM) derived from Magnolia officinalis exhibited remarkable antitumor activities in lung cancer. However, the epigenetic effect... | ['A549 Cells', 'Acetylation', 'Animals', 'Antineoplastic Agents, Phytogenic', 'Antineoplastic Combined Chemotherapy Protocols', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Biphenyl Compounds', 'Carcinoma, Non-Small-Cell Lung', 'Cell Cycle Checkpoints', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Epige... | 27,268,146 | [['A11.251.210.190.080', 'A11.251.860.180.080', 'A11.436.054'], ['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['D27.505.954.248.179'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['D02.455.426.559.389.185'], ['C04.588.894.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
War and medicine in the desert. A report of the 13th Evacuation Hospital in Saudi Arabia. | On Nov 21, 1990, the 13th Evacuation Hospital from Madison was called to active duty to support the US Army's VII Corps, which had been sent to the Persian Gulf from Germany. Physicians, nurses, and other medical personnel from reserve components and the active army were attached to our unit to complement our personnel... | ['Desert Climate', 'Hospitals, Military', 'Humans', 'Military Medicine', 'Saudi Arabia', 'Warfare'] | 1,949,870 | [['G16.500.275.071.325', 'N06.230.300.100.250.325'], ['N02.278.421.510.180.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.500'], ['Z01.252.245.500.750'], ['I01.880.735.950.500']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
[Diving accidents. Emergency treatment of serious diving accidents]. | Decompression injuries are potentially life-threatening incidents mainly due to a rapid decline in ambient pressure. Decompression illness (DCI) results from the presence of gas bubbles in the blood and tissue. DCI may be classified as decompression sickness (DCS) generated from the liberation of gas bubbles following ... | ['Barotrauma', 'Decompression Sickness', 'Diving', 'Embolism, Air', 'Emergency Medical Services', 'Humans'] | 15,565,421 | [['C26.120'], ['C26.120.248'], ['I03.450.642.845.945.500.110', 'N06.230.150.150'], ['C14.907.355.350.254'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Characteristics of peroxyacetyl nitrate pollution during a 2015 winter haze episode in Beijing. | Peroxyacetyl nitrate (PAN) are effective indicators of photochemical pollution, and also play an important role in regional oxidant balance. Surprisingly, in recent years, PAN have also been detected under conditions that do not favor the photochemical processes. To obtain a better understanding of the mechanisms of fo... | ['Air Pollutants', 'Beijing', 'China', 'Environmental Monitoring', 'Environmental Pollution', 'Hydroxyl Radical', 'Ozone', 'Particulate Matter', 'Peracetic Acid', 'Seasons'] | 30,352,352 | [['D27.888.284.101'], ['Z01.252.474.164.225', 'Z01.433.114'], ['Z01.252.474.164'], ['N06.850.460.350.080', 'N06.850.780.375'], ['N06.850.460'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'], ['D01.362.670.600'], ['D20.633'], ['D02.241.081.018.664'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.23... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Biological activities of 7-dehydrocholesterol-derived oxysterols: implications for Smith-Lemli-Opitz syndrome. | Smith-Lemli-Opitz syndrome (SLOS) is a metabolic and developmental disorder caused by mutations in the gene encoding the enzyme 7-dehydrocholesterol reductase (Dhcr7). This reductase catalyzes the last step in cholesterol biosynthesis, and levels of 7-dehydrocholesterol (7-DHC), the substrate for this enzyme, are eleva... | ['Animals', 'Cell Differentiation', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Dehydrocholesterols', 'Dose-Response Relationship, Drug', 'Gene Expression Profiling', 'Mice', 'Neurons', 'Oxidation-Reduction', 'Oxidoreductases Acting on CH-CH Group Donors', 'Peroxides', 'Smith-Lemli-Opitz Syndrome', 'Tim... | 20,702,862 | [['B01.050'], ['G04.152'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['D04.210.500.247.222.222.347.200', 'D04.210.500.247.808.197.250', 'D10.570.938.208.320'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.393.332'], ['B01.050.150.900.649.313.992.635.505.500'], ['A08.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synchronous anal canal carcinoma in a heterosexual couple. | BACKGROUND: Sexually transmitted Human Papilloma Virus (HPV) infection is a known risk factor for cancer of the anal canal in both men and women.CASE PRESENTATION: We describe a report of synchronous carcinoma of the anal canal in a heterosexual couple. High risk type 16 HPV DNA was detected in both tumors.CONCLUSION: ... | ['Anus Neoplasms', 'Biopsy', 'Female', 'Heterosexuality', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasms, Multiple Primary', 'Papillomaviridae', 'Papillomavirus Infections', 'Sexual Partners', 'Tomography, X-Ray Computed'] | 30,200,930 | [['C04.588.274.476.411.307.790.040', 'C06.301.371.411.307.790.040', 'C06.405.249.411.307.790.040', 'C06.405.469.491.307.790.040', 'C06.405.469.860.101.163', 'C06.405.469.860.180.500.040'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum. | Unlike plants and invertebrates, mammals reportedly lack proteins displaying asparagine (N)-linked paucimannosylation (mannose(1-3)fucose(0-1)N-acetylglucosamine(2)Asn). Enabled by technology advancements in system-wide biomolecular characterization, we document that protein paucimannosylation is a significant host-der... | ['Azure Stains', 'Blotting, Western', 'Chromatography, Liquid', 'Glycosylation', 'HL-60 Cells', 'Humans', 'Mannosides', 'Neutrophils', 'Pseudomonas aeruginosa', 'Sputum', 'Tandem Mass Spectrometry'] | 25,645,918 | [['D02.886.369.080', 'D03.633.300.783.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.181.400'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['B01.050.150.900.649.313.988.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tiny Microbes, Big Yields: enhancing food crop production with biological solutions. | Plant-associated microbiomes have tremendous potential to improve plant resilience and yields in farming systems. There is increasing evidence that biological technologies that use microbes or their metabolites can enhance nutrient uptake and yield, control pests and mitigate plant stress responses. However, to fully r... | ['Bacteria', 'Crop Production', 'Crops, Agricultural', 'Microbiota', 'Soil Microbiology'] | 28,840,959 | [['B03'], ['J01.040.227'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
In-vitro activity of ofloxacin, levofloxacin and D-ofloxacin against staphylococci. | The in-vitro activity of levofloxacin was compared with ofloxacin and D-ofloxacin against 130 isolates of Staphylococcus aureaus and 117 isolates of coagulase-negative staphylococci, using the agar dilution method. In general, levofloxacin was equally active or up to fourfold more active than ofloxacin against all stap... | ['Anti-Infective Agents', 'Drug Resistance, Microbial', 'Levofloxacin', 'Microbial Sensitivity Tests', 'Ofloxacin', 'Staphylococcus', 'Staphylococcus aureus', 'Stereoisomerism'] | 8,877,540 | [['D27.505.954.122'], ['G06.225', 'G07.690.773.984.269'], ['D03.633.100.810.835.322.500.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D03.633.100.810.835.322.500'], ['B03.300.390.400.800.750', 'B03.353.500.750.750', 'B03.510.100.750.750', 'B03.510.400.790.750'], ['B03.300.390.400.800.750.100',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Targeting cholesterol with â-cyclodextrin sensitizes cancer cells for apoptosis. | We found that targeting cholesterol with beta-cyclodextrin (bCD) and its derivatives disrupted signal transduction between PI3K and AKT, attenuating AKT pro-survival signals. In their absence, 2-deoxyglucose (2DG) caused anti-apoptotic protein Mcll to dissociate from pro-apoptotic Bak at mitochondria. Normally Bak is s... | ['2-Hydroxypropyl-beta-cyclodextrin', 'Aniline Compounds', 'Animals', 'Anticholesteremic Agents', 'Antimetabolites', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Cell Line, Tumor', 'Crosses, Genetic', 'Deoxyglucose', 'Drug Synergism', 'Humans'... | 26,606,906 | [['D04.345.103.333.500', 'D09.301.915.400.375.333.500', 'D09.698.365.855.400.375.333.500'], ['D02.092.146'], ['B01.050'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D27.505.519.186', 'D27.888.569.042'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G04.146.954.035'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Depolarization of the neuronal membrane caused by cotransport of taurine and sodium. | C 1300 neuroblastoma cells were cultured and used to study the effect of sodium dependent taurine transport on the membrane potential. Measuring net accumulation of taurine and the depolarization caused by externally applied taurine, we found both processes become active at an external concentration of taurine of 1 mM ... | ['Cell Line', 'Humans', 'Neuroblastoma', 'Neurons', 'Sodium', 'Taurine'] | 2,325,829 | [['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.600.590.650.550', 'C04.557.470.670.590.650.550', 'C04.557.580.625.600.590.650.550'], ['A08.675', 'A11.671'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725'], ['D02.455.326.146.100.850', 'D02.886.645.600.055... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development and Validation of the MiPrep Survey: An Instrument Assessing Patients' Perceived Preparation for Medical Interventions Including Medical Imaging, Radiotherapy, and Surgery. | BACKGROUND: Adequately preparing patients for medical interventions is an important component of quality healthcare. Nevertheless, few instruments for assessing patients' preparation exist.OBJECTIVES: To develop a psychometrically rigorous instrument to assess patients' perceptions of the quality of preparation.METHODS... | ['Adult', 'Aged', 'Aged, 80 and over', 'Diagnostic Imaging', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patients', 'Perception', 'Psychometrics', 'Reproducibility of Results', 'Self Efficacy', 'Surgical Procedures, Operative', 'Surveys and Questionnaires'] | 31,198,188 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.643'], ['F02.463.593'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['F01.752.747.792.700'], ['E04'], ['E05.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of contrast-enhanced SPACE and CISS in evaluating cavernous sinus invasion by pituitary macroadenomas on 3-T magnetic resonance. | PURPOSE: SPACE (sampling perfection with application-optimized contrasts by using different flip angle evolutions) and CISS (constructive interference in steady state) are 3-dimensional sequences that can increase the signal intensity of cavernous sinus. The purpose of this study was to determine whether contrast-enhan... | ['Adenoma', 'Adult', 'Aged', 'Cavernous Sinus', 'Contrast Media', 'Female', 'Humans', 'Image Enhancement', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Pituitary Neoplasms', 'Prospective Studies', 'Young Adult'] | 25,526,399 | [['C04.557.470.035'], ['M01.060.116'], ['M01.060.116.100'], ['A07.015.908.224.334'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.697.645', 'C23.550.727.645'], ['C04.588.322.609', 'C04... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Phototoxic keratoconjunctivitis from coal-tar pitch volatiles. | Roofers working with coal-tar pitch develop burning eyes and conjunctivitis which they subjectively associate with sun exposure. A coal-tar pitch distillate instilled in the conjunctivae of rabbits produced minimal or mild irritation in the absence of ultraviolet radiation, but irradiation with long-ultraviolet produce... | ['Animals', 'Coal Tar', 'Environmental Exposure', 'Humans', 'Keratoconjunctivitis', 'Occupational Diseases', 'Photosensitivity Disorders', 'Rabbits', 'Seasons', 'Sunlight', 'Ultraviolet Rays', 'Weather'] | 918,667 | [['B01.050'], ['D20.749.354'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.187.183.394', 'C11.204.564.585'], ['C24'], ['C17.800.600'], ['B01.050.150.900.649.313.968.700'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G01.358.500.505.650.836', 'G01.750.250.650.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characteristics of prolinase against various iminodipeptides in erythrocyte lysates from a normal human and a patient with prolidase deficiency. | The effect of various amino acids and MnCl2 on prolinase activity in erythrocyte lysates from a healthy individual and a patient with prolidase deficiency was investigated. A concentration of 0.1 mM MnCl2 increased prolinase activity in normal erythrocytes against pro-gly, pro-glu, pro-leu, pro-ser and pro-phe, but inh... | ['Amino Acids', 'Case-Control Studies', 'Chlorides', 'Dipeptidases', 'Dipeptides', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Erythrocytes', 'Humans', 'Imines', 'Isomerism', 'Kinetics', 'Manganese Compounds'] | 15,552,267 | [['D12.125'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D08.811.277.656.350.297'], ['D12.644.456.345'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.389'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The superficial buffer barrier in vascular smooth muscle. | Force development and fura-2 fluorescence were simultaneously measured in the rabbit inferior vena cava. Discharging SR Ca2+ with either caffeine or norepinephrine prior to stimulation of Ca2+ influx induced a delay of 30-70 s between the intracellular Ca2+ signal and development of force. This delay was abolished by t... | ['Animals', 'Caffeine', 'Calcium', 'Calcium Radioisotopes', 'Calcium-Transporting ATPases', 'Fura-2', 'In Vitro Techniques', 'Male', 'Muscle Contraction', 'Muscle, Smooth, Vascular', 'Rabbits', 'Sarcoplasmic Reticulum', 'Terpenes', 'Thapsigargin', 'Vena Cava, Inferior'] | 1,386,774 | [['B01.050'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.268.552.100.500.325', 'D01.496.098.325', 'D01.496.749.113', 'D01.552.539.288.500.325'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.58... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A case-control study of occupational risk factors for bladder cancer in Canada. | OBJECTIVE: To investigate occupational risk factors for bladder cancer in seven Canadian provinces.METHODS: We analysed a population-based case-control dataset of 887 individuals with incident, histologically confirmed bladder cancer between 1994 and 1997. Controls (2847) frequency matched for age and gender were surve... | ['Adult', 'Aged', 'Canada', 'Case-Control Studies', 'Female', 'Humans', 'Industry', 'Male', 'Middle Aged', 'Occupational Diseases', 'Occupational Exposure', 'Odds Ratio', 'Risk Factors', 'Sex Factors', 'Urinary Bladder Neoplasms'] | 15,801,485 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.567.176'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['M01.060.116.630'], ['C24'], ['N06.850.460.350.600'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590'... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Do shallow soil, low water availability, or their combination increase the competition between grasses with different root systems in karst soil? | Uneven soil depth and low water availability are the key limiting factors to vegetation restoration and reconstruction in limestone soils such as in vulnerable karst regions. Belowground competition will possibly increase under limited soil resources. Here, we investigate whether low resource availability (including sh... | ['Biomass', 'Plant Roots', 'Poaceae', 'Soil', 'Water'] | 28,283,974 | [['G16.500.275.157.100', 'N06.230.124.100'], ['A18.400'], ['B01.650.940.800.575.912.250.822'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prospects for axonal regrowth in spinal cord injury. | Some of the evidence relating to the possible cellular relationships in regenerating mammalian central nervous tissue is reviewed. From this review it is suggested that data do exist which reveal a potential for regeneration based upon the basic properties and behavior of axons and glial cells. Models of tissue injury ... | ['Animals', 'Axons', 'Humans', 'Nerve Regeneration', 'Spinal Cord Injuries'] | 2,713,719 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.561.585', 'G16.762.611'], ['C10.228.854.763', 'C10.900.850', 'C26.819']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantifying the Oligomeric States of Membrane Proteins in Cells through Super-Resolution Localizations. | Transitions between different oligomeric states of membrane proteins are essential for proper cellular functions. However, the quantification of their oligomeric states in cells is technically challenging. Here we developed a new method to quantify oligomeric state(s) of highly expressed membrane proteins using the pro... | ['Escherichia coli', 'Escherichia coli Proteins', 'Membrane Transport Proteins', 'Microscopy', 'Models, Chemical', 'Models, Theoretical', 'Monosaccharide Transport Proteins', 'Protein Multimerization'] | 30,384,609 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D12.776.157.530', 'D12.776.543.585'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['E05.599.495'], ['E05.599'], ['D12.776.157.530.500', 'D12.776.543.585.500'], ['G02.111.694']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
How the presence of rhinoconjunctivitis and the severity of asthma modify the relationship between obesity and asthma in children 6-7 years old. | BACKGROUND: The association between asthma and obesity in children, and the effect modification of allergy on this association have not been fully established. Aims The objective of the study was to know the effect modification of the severity of asthma and of the coexistence of rhinoconjunctivitis (RC) in the relation... | ['Asthma', 'Body Mass Index', 'Child', 'Conjunctivitis, Allergic', 'Cross-Sectional Studies', 'Female', 'Humans', 'Logistic Models', 'Male', 'Obesity', 'Risk Factors', 'Sex Factors', 'Spain', 'Surveys and Questionnaires'] | 18,462,453 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['C11.187.183.200', 'C20.543.480.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.9... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Impact of Oxygenation Status on 18F-FDG Uptake in Solid Tumors. | The influence of changes in tumor oxygenation (monitored by EPR oximetry) on the uptake of 18F-FDG tracer was evaluated using micro-PET in two different human tumor models. The 18F-FDG uptake was higher in hypoxic tumors compared to tumors that present a pO2 value larger than 10 mmHg. | ['Animals', 'Cell Line, Tumor', 'Electron Spin Resonance Spectroscopy', 'Fluorodeoxyglucose F18', 'Humans', 'Mice', 'Neoplasms', 'Oxygen', 'Positron-Emission Tomography'] | 26,782,213 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.196.867.519.274'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04'], ['D01.268.185.550', 'D01.362.670'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.710.800.3... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Specialist approach to childhood asthma: does it exist? | Twenty six paediatricians and 21 consultant physicians concerned in the care of children with asthma answered a postal questionnaire on various aspects of the management of asthma, attitudes to referral, and the nature of advice given to parents and children. The 47 specialists had considerable differences in opinion f... | ['Asthma', 'Attitude of Health Personnel', 'Child', 'Child, Preschool', 'Consultants', 'Female', 'Humans', 'Infant', 'Male', 'Pediatrics', 'United Kingdom'] | 6,409,273 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['F01.100.050', 'N05.300.100'], ['M01.060.406'], ['M01.060.406.448'], ['M01.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['H02.403.670'], ['Z01.542.363']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Soy protein products and heme iron absorption in humans. | Dual radioiron tags were used to measure both heme and nonheme iron absorption simultaneously from meat-containing meals in 76 healthy male volunteers. Partial substitution of beef with soy flour reduced the availability of nonheme iron but improved the percentage absorption of heme iron significantly (27 to 59% rise).... | ['Adolescent', 'Adult', 'Animals', 'Biological Availability', 'Cattle', 'Dietary Proteins', 'Heme', 'Humans', 'Intestinal Absorption', 'Iron', 'Male', 'Meat', 'Middle Aged', 'Plant Proteins', 'Soybeans'] | 4,038,429 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['B01.050.150.900.649.313.500.380.271'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Rho GTPase Cdc42 is essential for human T-cell development. | BACKGROUND: Rho GTPases are involved in the regulation of many cell functions, including some related to the actin cytoskeleton. Different Rho GTPases have been shown to be important for T-cell development in mice. However, their role in human T-cell development has not yet been explored.DESIGN AND METHODS: We examined... | ['Blotting, Western', 'Cell Movement', 'Cell Polarity', 'Chemokine CXCL12', 'Chemotaxis, Leukocyte', 'Child', 'Enzyme Inhibitors', 'Flow Cytometry', 'Gene Expression', 'Humans', 'Lymphocyte Activation', 'Organ Culture Techniques', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Signal Transduction... | 20,207,844 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.198', 'G07.568.500.180'], ['G04.250'], ['D12.644.276.374.200.120.600', 'D12.776.467.374.200.120.600', 'D23.125.300.120.600', 'D23.469.200.120.600', 'D23.529.374.200.120.600'], ['G04.198.424.233'], ['M01.060.406']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Don't get caught out! A rare case of a calcified urachal remnant mimicking a bladder calculus. | Computer tomography through the kidneys, ureters and bladder (CT KUB) is the mainstay investigation of suspected renal tract calculi. However, several pathologies other than renal tract calculi can cause apparent urinary bladder calcification. We describe the case of a 45 year old man who presented with left sided rena... | ['Calcinosis', 'Diagnosis, Differential', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Urachus', 'Urinary Bladder Calculi'] | 23,705,044 | [['C18.452.174.130'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['A16.890'], ['C12.777.829.720', 'C12.777.967.500.925', 'C13.351.968.829.521', 'C13.351.968.967.500.925', 'C23.300.175.850.875']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Client-server technology for merging practices. | Mergers, acquisitions and multiple care sites have made day-to-day management of information a logistical nightmare for medical group managers. As medical groups consolidate, each care site, typically, joins the new organization using stand-alone billing, accounting and scheduling packages. These legacy systems offer n... | ['Benchmarking', 'Community Networks', 'Computer Communication Networks', 'Decision Support Techniques', 'Group Practice', 'Health Facility Merger', 'Investments', 'Organizational Affiliation', 'Organizational Culture', 'Practice Management, Medical', 'Systems Integration', 'United States'] | 10,178,594 | [['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['I01.880.853.500.300', 'L01.313.500.750.300.184', 'N02.421.143.202'], ['L01.224.230.110'], ['E05.245', 'L01.313.500.750.190'], ['N04.452.758.244'], ['N02.278.235'], ['N03.219.702'], ['N04.452.602'], ['N04.452.606'], ['N04... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
ENDOR from nitrogens and protons in low spin ferric heme and hemoprotein. | Electron nuclear double resonance (ENDOR) signals have been obtained from iron-linked nitrogens in frozen solutions of cytochrome c, metmyoglobin cyanide, and a low spin protohemin mercaptide complex. Hyperfine couplings from heme protons have also been obtained from metmyoglobin cyanide and from a low spin protohemin ... | ['Binding Sites', 'Cyanides', 'Cytochrome c Group', 'Electron Spin Resonance Spectroscopy', 'Heme', 'Hemeproteins', 'Magnetic Resonance Spectroscopy', 'Molecular Conformation', 'Myoglobin', 'Protein Binding', 'Protein Conformation'] | 181,067 | [['G02.111.570.120'], ['D01.248.497.158.291', 'D01.625.400.100'], ['D08.244.286', 'D12.776.422.220.286'], ['E05.196.867.519.274'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D12.776.422'], ['E05.196.867.519'], ['G02.111.570.820'], ['D12.776.21... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The arts and medicine: a challenging relationship. | This paper discusses various justifications for including medical humanities and art in healthcare education. It expresses concern about portrayals of the humanities and art as benign and servile in relation to medicine and the health professions. An alternative is for the humanities to take a more active role within m... | ['Art', 'Biology', 'Education, Medical', 'Human Body', 'Humans', 'Medicine', 'Medicine in the Arts', 'Technology'] | 22,114,348 | [['K01.093'], ['H01.158.273'], ['I02.358.399'], ['I01.076.201.450.560', 'K01.093.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403'], ['K01.093.530'], ['J01.897']] | ['Humanities [K]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
Inhibition of KATP channel activity augments baroreflex-mediated vasoconstriction in exercising human skeletal muscle. | In the present investigation we examined the role of ATP-sensitive potassium (K(ATP)) channel activity in modulating carotid baroreflex (CBR)-induced vasoconstriction in the vasculature of the leg. The CBR control of mean arterial pressure (MAP) and leg vascular conductance (LVC) was determined in seven subjects (25 +/... | ['Adenosine Triphosphate', 'Adult', 'Anti-Arrhythmia Agents', 'Baroreflex', 'Carotid Body', 'Exercise', 'Female', 'Glyburide', 'Humans', 'Knee', 'Male', 'Muscle, Skeletal', 'Potassium Channel Blockers', 'Potassium Channels', 'Rest', 'Sympathetic Nervous System', 'Vasoconstriction'] | 15,345,750 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['M01.060.116'], ['D27.505.954.411.097'], ['G09.330.380.057', 'G11.561.731.063'], ['A08.675.650.915.500.600.150', 'A08.800.950.500.600.150', 'A11.671.650.915.500.600.150'], ['G11.427.410.698.277', 'I03.350'], ['D02.065.950.828.575', 'D02.88... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Photodynamic therapy for rheumatoid arthritis? | BACKGROUND AND OBJECTIVE: The only early surgical therapy of rheumatoid arthritis is synovectomy. But even an arthroscopic synovectomy is restricted to more or less big joints. It has been shown recently that for smaller joints a laser synovectomy is possible but more time-consuming than with mechanical instruments. An... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Cells, Cultured', 'Chi-Square Distribution', 'Chloroquine', 'Fibroblasts', 'Humans', 'Laser Therapy', 'Methotrexate', 'Photochemotherapy', 'Piroxicam', 'Sclerosing Solutions', 'Sodium Morrhuate'] | 9,328,983 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A11.251'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D03.633.100.810.050.180'], ['A11.329... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Reproducibility of tumor volume measurement at microCT colonography in living mice. | RATIONALE AND OBJECTIVES: We sought to demonstrate the viability of microcomputed tomographic colonography (muCTC) as a tool for monitoring tumorigenesis in mouse models of human colorectal cancer during prospective longitudinal studies. The precision and accuracy of volumetric measurements were determined to assess wh... | ['Algorithms', 'Alleles', 'Animals', 'Colonic Neoplasms', 'Colonography, Computed Tomographic', 'Disease Models, Animal', 'Genes, APC', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Insufflation', 'Longitudinal Studies', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred Strains', 'Prospective Studies'... | 18,280,931 | [['G17.035', 'L01.224.050'], ['G05.360.340.024.340.030'], ['B01.050'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E01.370.350.350.810.180', 'E01.370.350.600.350.700.810.180', 'E01.370.350.700.700.810.180', 'E01.370.350.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Hemodynamic effects of external cardiac massage in trauma shock. | The effectiveness of closed chest cardiopulmonary resuscitation (CCCPR) in maintaining cardiac output has been well studied in cardiac arrest. Trauma surgeons most often encounter shock secondary to hypovolemia or cardiac tamponade, and the effectiveness of CCCPR in that setting has not been established. To determine t... | ['Animals', 'Blood Pressure', 'Cardiac Tamponade', 'Heart Massage', 'Papio', 'Resuscitation', 'Shock, Traumatic'] | 2,810,421 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14.280.155'], ['E02.365.647.375', 'E04.100.376.458', 'E04.928.220.380'], ['B01.050.150.900.649.313.988.400.112.199.120.610'], ['E02.365.647'], ['C23.550.835.888', 'C26.797']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Denaturing gradient gel electrophoresis profiles of bacteria from the saliva of twenty four different individuals form clusters that showed no relationship to the yeasts present. | OBJECTIVES: The aim was to investigate the relationship between groups of bacteria identified by cluster analysis of the DGGE fingerprints and the amounts and diversity of yeast present.METHODS: Bacterial and yeast populations in saliva samples from 24 adults were analysed using denaturing gradient gel electrophoresis ... | ['Adult', 'Aged', 'Bacteria', 'Biofilms', 'Candida', 'Denaturing Gradient Gel Electrophoresis', 'Female', 'Humans', 'In Vitro Techniques', 'Male', 'Middle Aged', 'Saccharomyces cerevisiae', 'Saliva'] | 28,577,425 | [['M01.060.116'], ['M01.060.116.100'], ['B03'], ['A20.593', 'G06.120'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['E05.196.401.402.117', 'E05.301.300.319.201'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['M01.060.116.630'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Photophysical studies on the interaction of formamide and alkyl substituted amides with photoinduced electron transfer (PET) based acridinedione dyes in water. | Interaction of photoinduced electron transfer (PET) based acridinedione dye (ADR 1) with amides like formamide, acetamide and dimethylformamide (DMF) were investigated by fluorescence spectral techniques. A fluorescence enhancement accompanied with a blue shift in the emission maximum was observed on the addition of am... | ['Acridines', 'Amides', 'Electron Transport', 'Fluorescent Dyes', 'Formamides', 'Photochemical Processes', 'Water'] | 21,769,603 | [['D03.633.300.046'], ['D02.065'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D02.065.463', 'D02.241.081.420.500'], ['G02.740'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
cDNA cloning and expression characterization of serum transferrin gene from oriental weatherfish Misgurnus anguillicaudatus. | In this study, the cDNA coding serum transferrin (stf) of Misgurnus anguillicaudatus (mastf) was cloned. mastf cDNA is composed of 2326 bp with a 2007 bp open reading frame encoding 668 amino acids. The deduced Mastf protein consists of a signal peptide, two lobes (N and C-lobes) and signature motifs of transferrin (Tf... | ['Aeromonas', 'Amino Acid Motifs', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'Cypriniformes', 'DNA, Complementary', 'Fish Proteins', 'Head Kidney', 'Liver', 'Molecular Sequence Data', 'Open Reading Frames', 'Phylogeny', 'RNA, Messenger', 'Sequence Analysis, DNA', 'Spleen', 'Transferrin'] | 24,673,686 | [['B03.440.450.019.025'], ['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['B01.050.150.900.493.200'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Slow-binding inhibition of soybean lipoxygenase-1 by luteolin. | Luteolin, isolated from the seeds of Perilla frutescens (perilla seeds), inhibited the peroxidation of linoleic acid catalyzed by soybean lipoxygenase-1 (EC 1.13.11.12, Type 1) with an IC(50) of 5.0 M (1.43 ìg/mL) noncompetitively. The progress curves for an enzyme reaction indicate that luteolin shows slow binding kin... | ['Chromatography, High Pressure Liquid', 'Kinetics', 'Lipid Peroxidation', 'Lipoxygenase', 'Lipoxygenase Inhibitors', 'Luteolin', 'Molecular Structure', 'Oxidation-Reduction', 'Perilla', 'Protein Binding', 'Seeds', 'Soybeans', 'Time Factors'] | 23,139,133 | [['E05.196.181.400.300'], ['G01.374.661', 'G02.111.490'], ['G02.111.515', 'G03.295.531.587'], ['D08.811.682.690.416.583.625', 'D12.776.556.579.374.568.750'], ['D27.505.519.389.480'], ['D03.383.663.283.266.450.260.555', 'D03.633.100.150.266.450.260.555'], ['G02.111.570', 'G02.466'], ['G02.700', 'G03.295.531'], ['B01.650... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. | Oligomerization of tau is a key process contributing to the progressive death of neurons in Alzheimer's disease. Tau is modified by O-linked N-acetylglucosamine (O-GlcNAc), and O-GlcNAc can influence tau phosphorylation in certain cases. We therefore speculated that increasing tau O-GlcNAc could be a strategy to hinder... | ['Acetylglucosamine', 'Adaptor Proteins, Signal Transducing', 'Alzheimer Disease', 'Animals', 'Carbohydrate Conformation', 'Disease Models, Animal', 'Enzyme Inhibitors', 'Female', 'Humans', 'Mice', 'Mice, Transgenic', 'N-Acetylglucosaminyltransferases', 'Neurodegenerative Diseases', 'Neurons', 'Phosphorylation', 'Pyran... | 22,366,723 | [['D09.067.342.531.050'], ['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['B01.050'], ['G02.111.570.820.235'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of phenols using simultaneous steam distillation-extraction. | Simultaneous distillation-extraction was proposed as a preconcentration step for the determination of phenol and its derivatives in aqueous and soil samples. Detection limits of 0.01 mg l(-1) (water) and 0.1 mg kg(-1) (soil) were achieved by gas chromatography-flame ionization detection. The described preconcentration ... | ['Chromatography, Gas', 'Phenols', 'Sensitivity and Specificity', 'Steam'] | 10,670,728 | [['E05.196.181.349'], ['D02.455.426.559.389.657'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['D01.045.250.875.800', 'D01.248.497.158.459.650.800', 'D01.650.550.925.800', 'G16.500.887', 'N06.230.650']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The association of health risks with on-the-job productivity. | OBJECTIVE: Decreased on-the-job productivity represents a large yet poorly characterized indirect cost to employers. We studied the impact of employee health risk factors on self-reported worker productivity (presenteeism).METHODS: Using a brief version of the Work Limitation Questionnaire incorporated into a Health Ri... | ['Adolescent', 'Adult', 'Efficiency', 'Female', 'Health Behavior', 'Health Status Indicators', 'Humans', 'Industry', 'Job Satisfaction', 'Life Style', 'Male', 'Middle Aged', 'Midwestern United States', 'Occupational Health', 'Prospective Studies', 'Regression Analysis', 'Risk Assessment', 'Risk Factors', 'Surveys and Q... | 16,093,926 | [['M01.060.057'], ['M01.060.116'], ['F02.784.692.351', 'N04.452.209'], ['F01.145.488'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['F02.784.692.425'], ['F01.829.458'], ['M01.060.116.630'], ['Z01.107.567.875.51... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Light and electron microscopic morphology of the temporomandibular joint in growing and mature crab-eating monkeys (Macaca fascicularis): the condylar articular layer. | In an attempt to establish maturational alterations in the morphology of the articular tissue layer, mandibular condyles of four immature and four mature male monkeys (Macaca fascicularis) were studied using light microscopy as well as scanning and transmission electron microscopy. Specimens were fixed in situ by perfu... | ['Animals', 'Cartilage', 'Humans', 'Macaca fascicularis', 'Microscopy, Electron', 'Temporomandibular Joint'] | 2,372,135 | [['B01.050'], ['A02.165', 'A10.165.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['E01.370.350.515.402', 'E05.595.402'], ['A02.835.583.861', 'A14.907']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of cysteine protease cathepsin L is increased in endometrial cancer and correlates with expression of growth regulatory genes. | Proteases contribute to tumor invasion and metastasis by degrading basement membranes and extracellular matrix (ECM). In this study, we compared gene expression levels of two proteases, cysteine protease Cathepsin L2 (CTSL2) and matrix metalloproteinase MMP11, in human endometrium and endometrial cancer. Our data demon... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cathepsins', 'Cyclin B1', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cysteine Endopeptidases', 'Endometrial Neoplasms', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Ki-67 Antigen', 'Matrix Metalloproteinase 11', 'Middle Aged', 'RNA, Messenger'] | 22,452,389 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.277.656.224'], ['D12.644.360.262.120.100', 'D12.776.167.218.120.100', 'D12.776.476.262.120.100'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.250'], ['D0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Surfactin, Iturin, and Fengycin Biosynthesis by Endophytic Bacillus sp. from Bacopa monnieri. | Endophytic microorganisms which are ubiquitously present in plants may colonize intracellularly or intercellularly without causing any diseases. By living within the unique chemical environment of a host plant, they produce a vast array of compounds with a wide range of biological activities. Because of this, natural p... | ['Anti-Infective Agents', 'Antineoplastic Agents', 'Antioxidants', 'Antiviral Agents', 'Bacillus', 'Bacopa', 'Biological Products', 'Endophytes', 'Lipopeptides', 'Multigene Family', 'Peptides, Cyclic', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Tandem Mass Spectrometry'] | 27,021,396 | [['D27.505.954.122'], ['D27.505.954.248'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D27.505.954.122.388'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['B01.650.940.800.575.912.250.583.700.080'], ['D20.215'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Trifluoperazine stimulates the coordinate degradation of sphingomyelin and phosphatidylcholine in GH3 pituitary cells. | Prior studies demonstrated that 1,2-diacylglycerols stimulated degradation of the choline-containing phospholipids, phosphatidylcholine and sphingomyelin, in GH3 pituitary cells by a phospholipase A2 and a sphingomyelinase, respectively (Kolesnick, R. N. (1987) J. Biol. Chem. 262, 16759-16762). The present studies demo... | ['Animals', 'Cell Line', 'Ceramides', 'Choline', 'Cytosol', 'Diglycerides', 'Kinetics', 'Phosphatidylcholines', 'Pituitary Gland', 'Rats', 'Sphingomyelins', 'Trifluoperazine'] | 2,760,058 | [['B01.050'], ['A11.251.210'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D10.351.303'], ['G01.374.661', '... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Central, peripheral and resistance arterial reactivity: fluctuates during the phases of the menstrual cycle. | The purpose of this study was to document the temporal changes in vascular reactivity occurring simultaneously in central, peripheral and microvascular resistance arteries in the same cohort of women during the normal menstrual cycle. Twenty-three (n = 23) women (mean age (+/-SD) = 19 +/- 1 y) were tested during four p... | ['Adolescent', 'Arteries', 'Blood Flow Velocity', 'Blood Pressure', 'Brachial Artery', 'Cohort Studies', 'Endothelium, Vascular', 'Estradiol', 'Female', 'Follicular Phase', 'Humans', 'Luteal Phase', 'Menstrual Cycle', 'Nitric Oxide', 'Vascular Resistance', 'Young Adult'] | 20,404,025 | [['M01.060.057'], ['A07.015.114'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015.114.139'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['A07.015.700.500', 'A10.272.491.355'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], [... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
This mood is familiar and I don't deserve to feel better anyway: mechanisms underlying self-esteem differences in motivation to repair sad moods. | Why are people with low self-esteem (LSE) less motivated than people with high self-esteem (HSE) to improve sad moods? The present research examined whether feelings of personal deservingness contribute to this difference. Four experiments with undergraduate participants involved a sad mood induction, a manipulation of... | ['Affect', 'Female', 'Humans', 'Male', 'Motivation', 'Self Concept', 'Social Control, Informal', 'Sociometric Techniques', 'Surveys and Questionnaires'] | 19,159,137 | [['F01.470.047'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['F01.752.747.792'], ['I01.880.630'], ['I01.880.866'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[Assemblage composition and distribution of meiofauna in the southern Yellow Sea cold water mass during summer and autumn]. | In order to study the impact of the Yellow Sea cold water mass (YSCWM) on meiofauna, the composition, abundance, biomass of meiofauna and their relationships with environmental variables were analyzed through the samples from 8 stations investigated by R/V 'Dongfanghong II' in June and November, 2013. The results showe... | ['Animals', 'Biomass', 'Biota', 'China', 'Cold Temperature', 'Copepoda', 'Crustacea', 'Nematoda', 'Seasons', 'Seawater'] | 26,094,481 | [['B01.050'], ['G16.500.275.157.100', 'N06.230.124.100'], ['G16.500.275.157.049.100', 'N06.230.124.049.100'], ['Z01.252.474.164'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['B01.050.500.131.365.160'], ['B01.050.500.131.365']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Knowledge about and attitudes towards drinking among university students in Spain. | A total of 545 Spanish university students from the University of Valladolid, were surveyed in 1985 about their alcohol use, knowledge of the effects of alcohol, and attitudes towards social drinking and towards alcoholism and alcoholics. The knowledge regarding alcohol (mean scores 7.7 +/- 0.1, ranging 1-15) was assoc... | ['Adult', 'Alcohol Drinking', 'Alcoholism', 'Attitude to Health', 'Female', 'Health Education', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Spain', 'Students', 'Surveys and Questionnaires'] | 2,609,009 | [['M01.060.116'], ['F01.145.317.269'], ['C25.775.100.250', 'F03.900.100.350'], ['F01.100.150', 'N05.300.150'], ['I02.233.332', 'N02.421.726.407'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.846'], ['M01.848'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.52... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Correlation between Herrold egg yolk medium culture and real-time quantitative polymerase chain reaction results for Mycobacterium avium subspecies paratuberculosis in pooled fecal and environmental samples. | Real-time quantitative polymerase chain reaction (qPCR) testing for Mycobacterium avium subspecies paratuberculosis (MAP) in fecal samples is a rapid alternative to culture on Herrold egg yolk medium (HEYM), the traditional antemortem reference test for MAP. Although the sensitivity and specificity of these 2 tests hav... | ['Animals', 'California', 'Cattle', 'Cattle Diseases', 'Colony-Forming Units Assay', 'Culture Media', 'Dairying', 'Egg Yolk', 'Environment', 'Feces', 'Female', 'Mycobacterium avium subsp. paratuberculosis', 'New York', 'Paratuberculosis', 'Pennsylvania', 'Polymerase Chain Reaction', 'Regression Analysis', 'Vermont'] | 20,807,920 | [['B01.050'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['D27.720.470.305', 'E07.206'], ['J01.040.246'], ['A16.690.325', 'G07.203.300.470.800', 'J02.500.470.800'], ['G16.500.275', 'N06.230'], [... | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Development and validation of a Viviparous-1 STS marker for pre-harvest sprouting tolerance in Chinese wheats. | Pre-harvest sprouting (PHS) of wheat reduces the quality of wheat grain, and improving PHS tolerance is a priority in certain wheat growing regions where conditions favorable for PHS exist. Two new Viviparous-1 allelic variants related to PHS tolerance were investigated on B genome of bread wheat, and designated as Vp-... | ['Base Sequence', 'China', 'Genetic Markers', 'Germination', 'Molecular Sequence Data', 'Seeds', 'Sequence Tagged Sites', 'Triticum'] | 17,712,543 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.252.474.164'], ['D23.101.387', 'G05.695.450'], ['G07.345.625.249', 'G15.357'], ['L01.453.245.667'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['G05.360.340.024.810'], ['B01.650.940.800.575.912.250.822.918']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
Endothelial overexpression of Fas ligand decreases atherosclerosis in apolipoprotein E-deficient mice. | OBJECTIVE: Fas ligand (FasL) can induce apoptosis in cells bearing the Fas receptor. The role of FasL in the vasculature with regard to atherosclerosis is controversial. This study examined the function of endothelial FasL during atherosclerosis.METHODS AND RESULTS: Transgenic (Tg) mice that specifically overexpress di... | ['Animals', 'Aorta, Abdominal', 'Aorta, Thoracic', 'Aortic Diseases', 'Apolipoproteins E', 'Apoptosis', 'Arteriosclerosis', 'Diet, Atherogenic', 'Endothelium, Vascular', 'Fas Ligand Protein', 'Humans', 'Hypercholesterolemia', 'Inflammation', 'Leukocyte Count', 'Lipids', 'Macrophages', 'Membrane Glycoproteins', 'Mice', ... | 15,178,561 | [['B01.050'], ['A07.015.114.056.205'], ['A07.015.114.056.372'], ['C14.907.109'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['G04.146.954.035'], ['C14.907.137.126'], ['G07.203.650.240.242'], ['A07.015.700.500', 'A10.272.491.355'], ['D12.644.276.374.750.249', 'D12.776.395.550.312', 'D12.776.467.3... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Temperament and increased weight gain in infants. | The role of temperamental characteristics in accelerated and decelerated weight gain in normal infants has not been investigated previously except for differences in activity. The present study drew a random sample of 200 normal infants from a largely middle-class private practice. It found 24 infants who gained 30 or ... | ['Body Height', 'Body Weight', 'Child Behavior', 'Child Development', 'Humans', 'Infant', 'Infant Food', 'Motor Activity', 'Personality', 'Temperament'] | 4,008,657 | [['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['F01.145.179'], ['F01.525.200', 'G07.345.374.750'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Risk factors for child abuse: quantitative correlational design. | The aim of this research study is to identify risk factors typical of different types of suspected child abuse reported at a hospital. The study was based on 114 cases of children for whom some type of abuse was reported. Physical abuse was the most frequently reported of all types of suspected child abuse. Most victim... | ['Adolescent', 'Age Distribution', 'Child', 'Child Abuse', 'Child Abuse, Sexual', 'Child, Preschool', 'Cohort Studies', 'Emergency Service, Hospital', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Infant', 'Israel', 'Logistic Models', 'Male', 'Mandatory Reporting', 'Multivariate Analysis', 'Needs Assessment', 'Pr... | 24,263,252 | [['M01.060.057'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['I01.198.240.748.300', 'I01.198.240.856.350.250.255', 'I01.880.735.900.350.250.255'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.45... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Plasma exchange in two patients with rheumatoid vasculitis. | Plasma exchange was performed in 2 patients with classical rheumatoid arthritis, complicated in one case by necrotic vasculitis, and in the other by mononeuritis multiplex. Immediate improvement in the peripheral circulation was observed in both patients with subsequent healing of necroses and nerve function, respectiv... | ['Arthritis, Rheumatoid', 'Female', 'Humans', 'Male', 'Middle Aged', 'Plasma Exchange', 'Vasculitis'] | 7,063,814 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.095.135.750', 'E02.120.770.500', 'E02.912.715.500', 'E04.292.869.500'], ['C14.907.940']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of tumour necrosis factor (TNF) inhibitors in Clostridium difficile toxin-induced paw oedema and neutrophil migration. | Clostridium difficile produces a potent enterotoxin and a cytotoxin, toxin A and toxin B, respectively. These toxins are associated with pseudomembranous colitis and antibiotic-associated diarrhoea. In the present study, we investigated the oedematogenic activity of both toxins, characterizing the time-course and dose-... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Botulinum Toxins', 'Botulinum Toxins, Type A', 'Chemotaxis, Leukocyte', 'Clostridioides difficile', 'Dermatologic Agents', 'Edema', 'Enzyme Inhibitors', 'Male', 'Neutrophils', 'Pentoxifylline', 'Rats', 'Rats, Wistar', 'Thalidomide', 'Tumor Necrosis Factor-alpha'] | 11,453,371 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D08.811.277.656.300.480.153', 'D08.811.277.656.675.374.153', 'D12.776.097.156', 'D23.946.123.179'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A neurovascular island flap including a vein for the treatment of an acquired ring constriction. | We present a case of an acquired constriction band caused by a tight ring on the left middle finger of a 45-year-old man. Most of the constriction band was excised and the resulting defect reconstructed with a neurovascular island flap, including a dorsal digital vein, from the adjacent ring finger. The distal end of t... | ['Constriction, Pathologic', 'Fingers', 'Hand Deformities, Acquired', 'Humans', 'Male', 'Middle Aged', 'Surgical Flaps', 'Veins'] | 7,551,512 | [['C23.300.287'], ['A01.378.800.667.430'], ['C05.390.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A10.850.710', 'E07.862.710'], ['A07.015.908']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Probing spatial organization of DNA strands using enzyme-free hairpin assembly circuits. | Catalyzed hairpin assembly (CHA) is a robust enzyme-free signal-amplification reaction that has a wide range of potential applications, especially in biosensing. Although most studies of the analytical applications of CHA have focused on the measurement of concentrations of biomolecules, we show here that CHA can also ... | ['Base Sequence', 'Biosensing Techniques', 'DNA', 'DNA, Single-Stranded', 'Nanostructures', 'Nucleic Acid Conformation', 'Nucleic Acid Hybridization'] | 22,894,754 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.601.043'], ['D13.444.308'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['J01.637.512'], ['G02.111.570.820.486', 'G05.360.580'], ['E05.393.661', 'G02.111.611']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Expression of GC clusters in the yeast mitochondrial var 1 gene. Transcription into stable RNAs. | We have determined whether two 46-base pair (bp) GC-rich clusters present in the coding region of the yeast mitochondrial var 1 gene are transcribed and retained in the putative mRNA for the var 1 protein. One GC cluster is found in all var 1 alleles, while the other is optional; both are identical in sequence and, whe... | ['Base Sequence', 'DNA', 'DNA Restriction Enzymes', 'DNA, Mitochondrial', 'Genes', 'Genes, Fungal', 'Nucleic Acid Conformation', 'RNA, Fungal', 'Saccharomyces cerevisiae', 'Transcription, Genetic'] | 6,330,112 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.283.225'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['G02.111.570.820.486',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Influence of extracellular K+ concentrations on quinidine-induced K+ current inhibition in rat ventricular myocytes. | Hypokalaemia is one of the important risk factors for development of torsades de pointes. We recently reported that hypokalaemia increased the electrocardiographic QT interval in rats treated with quinidine, but did not alter the arrhythmogenic potency of quinidine. In this study, we have investigated the influence of ... | ['Adrenergic alpha-Antagonists', 'Animals', 'Cells, Cultured', 'Drug Interactions', 'Electrophysiology', 'Heart', 'Male', 'Patch-Clamp Techniques', 'Potassium', 'Potassium Channels', 'Quinidine', 'Rats'] | 10,716,610 | [['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['B01.050'], ['A11.251'], ['G07.690.773.968'], ['H01.158.344.528', 'H01.158.782.236'], ['A07.541'], ['E05.200.500.905', 'E05.242.800'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['D12.776.157.530.400.600', 'D12.776.543.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Sister chromatid exchange and chromosome aberration analyses in mice after in vivo exposure to acrylonitrile, styrene, or butadiene monoxide. | The use of polymers in plastic and rubber products has generated concern that monomers potentially active in biological systems may be eluted from these substances. We have evaluated two such monomers, acrylonitrile and styrene, for the induction of chromosome damage in mice. Butadiene monoxide, a presumed metabolite o... | ['Acrylonitrile', 'Animals', 'Chromosome Aberrations', 'Epoxy Compounds', 'Ethers, Cyclic', 'Injections, Intraperitoneal', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mutagenicity Tests', 'Nitriles', 'Sister Chromatid Exchange', 'Styrene', 'Styrenes'] | 3,709,426 | [['D02.626.095'], ['B01.050'], ['C23.550.210', 'G05.365.590.175'], ['D02.355.291.411'], ['D02.355.291', 'D04.345.241'], ['E02.319.267.530.490'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['E05.393.560', 'E05.940.560'], ['D02.626'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Examination of the thoracic cavity and lung lobectomy by means of thoracoscopy in dogs. | The feasibility of thoracoscopy for viewing the chest cavity and performing pulmonary lobectomy was assessed in 8 mongrel dogs. Previously, selective intubation had been performed in another group of dogs (n = 8) in order to monitor respiratory physiology and assess its safety. Each hemithorax was intubated using a dou... | ['Anesthesia, General', 'Animals', 'Biopsy', 'Carbon Dioxide', 'Dogs', 'Feasibility Studies', 'Hemoglobins', 'Intubation, Intratracheal', 'Lung', 'Oxygen', 'Sutures', 'Thoracoscopy'] | 9,592,615 | [['E03.155.197'], ['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.33... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Scientific tools, fake treatments, or triggers for psychological healing: how clinical trial participants conceptualise placebos. | Placebos are an essential tool in randomised clinical trials, where they are used to control for bias and contextual healing effects. Placebos and their effects are also studied from multiple diverse perspectives, but the perspectives of placebo recipients are seldom considered. Research shows that people form cognitiv... | ['Acupuncture Therapy', 'Adult', 'Attitude to Health', 'Female', 'Humans', 'Informed Consent', 'Interviews as Topic', 'Irritable Bowel Syndrome', 'Male', 'Middle Aged', 'Placebo Effect', 'Placebos', 'Randomized Controlled Trials as Topic', 'Research Subjects'] | 22,285,289 | [['E02.190.044'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['C06.405.469.158.272.60... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Macrophages utilize the mitochondrial calcium uniporter for profibrotic polarization. | Fibrosis in multiple organs, including the liver, kidney, and lung, often occurs secondary to environmental exposure. Asbestos exposure is one important environmental cause of lung fibrosis. The mechanisms that mediate fibrosis is not fully understood, although mitochondrial oxidative stress in alveolar macrophages is ... | ['Adolescent', 'Adult', 'Animals', 'Asbestosis', 'Calcium', 'Calcium Channels', 'Gene Expression Regulation', 'Haplotypes', 'Humans', 'Macrophages', 'Mice', 'Middle Aged', 'Pulmonary Fibrosis', 'Reactive Oxygen Species', 'Young Adult'] | 28,351,840 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['C08.381.483.581.125', 'C08.381.520.702.125', 'C24.800.127'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['G05.308'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical efficacy of magnesium supplementation in patients with type 2 diabetes. | Effects of magnesium (Mg) supplementation on nine mild type 2 diabetic patients with stable glycemic control were investigated. Water from a salt lake with a high natural Mg content (7.1%) (MAG21) was used for supplementation after dilution with distilled water to 100mg/100mL; 300mL/day was given for 30 days. Fasting s... | ['Blood Glucose', 'Blood Pressure', 'Diabetes Mellitus, Type 2', 'Dietary Supplements', 'Fasting', 'Female', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Magnesium', 'Male', 'Middle Aged', 'Treatment Outcome', 'Triglycerides', 'Water'] | 15,466,952 | [['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C18.452.394.750.149', 'C19.246.300'], ['G07.203.300.456', 'J02.500.456'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', '... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
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