Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Crystallization and preliminary X-ray diffraction analysis of the lectin from Canavalia boliviana Piper seeds. | Plant lectins are the most studied group of carbohydrate-binding proteins. Despite the high similarity between the members of the Diocleinae subtribe (Leguminosae) group, they present differing biological activities. Canavalia boliviana lectin (Cbol) was purified using a Sephadex G-50 column and crystallized in the pre... | ['Canavalia', 'Chromatography, Affinity', 'Crystallization', 'Crystallography, X-Ray', 'Electrophoresis, Polyacrylamide Gel', 'Plant Lectins', 'Seeds'] | 19,255,467 | [['B01.650.940.800.575.912.250.401.096'], ['E05.196.181.400.170'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.503.499', 'D12.776.765.678'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Prevalence and clinical implications of painful diabetic peripheral neuropathy in type 2 diabetes: results from a nationwide hospital-based study of diabetic neuropathy in Korea. | AIMS: To determine the prevalence and risk factors for painful diabetic peripheral neuropathy (PDPN) and evaluate sleep impairment and quality of life in patients with PDPN.METHODS: Data from the Korean Diabetes Association Neuropathy Study Group were used to evaluate 3999 patients with type 2 diabetes. PDPN was diagno... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 2', 'Diabetic Neuropathies', 'Female', 'Follow-Up Studies', 'Hospitals', 'Humans', 'Male', 'Middle Aged', 'Pain', 'Prevalence', 'Prognosis', 'Quality of Life', 'Republic of Korea', 'Sleep Wake Disorders'] | 24,438,877 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750.149', 'C19.246.300'], ['C10.668.829.300', 'C19.246.099.937'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['N02.278.421'], ['B01.050.150.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Flow cytometric analysis of the basophil cell activating impact of potential drug delivery nanoparticle-candidate. | INTRODUCTION: Carbon nanotubes – as artificial nano-size ranged materials –have increasing role in the modern biomedical, diagnostic and therapeutic applications.There is a promising option for their use as more potential drug carriers. Despite the favourable properties, their impact (accumulation, elimination, etc.) o... | ['Basophils', 'Drug Delivery Systems', 'Flow Cytometry', 'Humans', 'Hypersensitivity', 'Nanotubes, Carbon'] | 24,631,753 | [['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['E02.319.300'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Dynamic reconstruction of the fish locomotory wave]. | The inverse hydrodynamic task of the synthesis of a wave driver for aquatic organisms, in particular of fishes, has been solved. A multilink model of bending oscillations and the optimum phasings of transverse-rotary vibrations of parts was considered, which provides a maximum driving force of each link for two cases o... | ['Animals', 'Fishes', 'Models, Biological', 'Swimming'] | 19,334,642 | [['B01.050'], ['B01.050.150.900.493'], ['E05.599.395'], ['G11.427.410.568.800', 'G11.427.410.698.277.875', 'I03.350.875', 'I03.450.642.845.945.500']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
A mathematical model of in vivo bovine blastocyst developmental to gestational Day 15. | Bovine embryo growth involves a complex interaction between the developing embryo and the growth-promoting potential of the uterine environment. We have previously established links between embryonic factors (embryo stage, embryo gene expression), maternal factors (progesterone, body condition score), and embryonic gro... | ['Animals', 'Blastocyst', 'Cattle', 'Embryo Transfer', 'Embryonic Development', 'Female', 'Models, Theoretical', 'Pregnancy', 'Progesterone'] | 29,935,827 | [['B01.050'], ['A16.254.500'], ['B01.050.150.900.649.313.500.380.271'], ['E02.875.800.500', 'E05.820.800.500'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['E05.599'], ['G08.686.784.769'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Students' perception of a problem-based learning scenario in dental nurse education. | BACKGROUND: In July 2008, The General Dental Council implemented mandatory registration for Dental Nurses in the United Kingdom, recognising them as legally responsible for patient care. As dentistry comes to terms with the impact registration has on dental nurses, sustained advances in the teaching of students in othe... | ['Attitude of Health Personnel', 'Dental Assistants', 'Education, Dental', 'Humans', 'Patient Care', 'Problem-Based Learning', 'Program Evaluation', 'Students, Dental', 'Surveys and Questionnaires', 'United Kingdom'] | 23,050,503 | [['F01.100.050', 'N05.300.100'], ['M01.526.485.067.105.250', 'N02.360.067.105.250'], ['I02.358.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760', 'N02.421.585'], ['F02.463.425.720', 'I02.158.660', 'I02.903.565'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['M01.848.769.519'], ['E05.318.308.980'... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Regional hyperthermia by magnetic induction in a beagle dog model: analysis of thermal dosimetry. | We have investigated magnetic induction heating techniques for achieving normal tissue hyperthermia in a beagle dog model to clarify the physics and physiology of "regional heating," to develop an animal model of regional heating in humans, and to develop a method of rapid regional heating in dogs for a normal visceral... | ['Animals', 'Biophysical Phenomena', 'Biophysics', 'Body Temperature', 'Dogs', 'Electrodes', 'Female', 'Heating', 'Hyperthermia, Induced', 'Magnetics', 'Thermal Conductivity', 'Thermometers', 'Time Factors'] | 6,729,045 | [['B01.050'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['E01.370.600.875.374', 'G07.110'], ['B01.050.150.900.649.313.750.250.216.200'], ['E07.305.250'], ['N06.230.150.300'], ['E02.565'], ['H01.671.493'], ['G01.906.730'], ['E07.900'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The dynamics of RUNX1-RUNX1T1 transcript levels after allogeneic hematopoietic stem cell transplantation predict relapse in patients with t(8;21) acute myeloid leukemia. | BACKGROUND: The optimal monitoring schedules and cutoff minimal residual disease (MRD) levels for the accurate prediction of relapse at all time points after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remain unclear in patients with t(8;21) acute myeloid leukemia (AML).METHODS: RUNX1-RUNX1T1 transcr... | ['Adolescent', 'Adult', 'Allografts', 'Child', 'Child, Preschool', 'Chromosomes, Human, Pair 21', 'Chromosomes, Human, Pair 8', 'Core Binding Factor Alpha 2 Subunit', 'Female', 'Follow-Up Studies', 'Gene Expression Regulation, Leukemic', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Leukemia, Myeloid, Acute', '... | 28,166,825 | [['M01.060.057'], ['M01.060.116'], ['A01.941.500'], ['M01.060.406'], ['M01.060.406.448'], ['A11.284.187.520.300.505.510', 'G05.360.162.520.300.505.510'], ['A11.284.187.520.300.325.340', 'G05.360.162.520.300.325.340'], ['D12.776.930.155.200.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.4... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice. | Therapeutic and environmental aromatic amines and hydrazines are substrates for the arylamine N-acetyltransferases (NAT). In all, 10 transgenic lines containing either the human NAT1 or NAT2 transgene were developed using multiple promoters. The presence of the transgene was confirmed by determining copy number, mRNA a... | ['Animals', 'Arylamine N-Acetyltransferase', 'Cloning, Molecular', 'Cytomegalovirus', 'Humans', 'Isoenzymes', 'Liver', 'Mice', 'Mice, Transgenic', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Transgenes'] | 16,041,393 | [['B01.050'], ['D08.811.913.050.134.138'], ['E05.393.220'], ['B04.280.382.150.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['D13.444.735.544'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reduction in cervical probing analgesia by repeated prior exposure to cold-water swims. | Previous work has established that stimulation of the vaginal cervix (cervical probing: CP) and cold-water swims (CWS) each produce analgesia in rats that is affected similarly by catecholaminergic mechanisms, but differentially by serotoninergic and opioid mechanisms. The present study examined whether CP analgesia, l... | ['Afferent Pathways', 'Animals', 'Arousal', 'Brain', 'Cervix Uteri', 'Cold Temperature', 'Female', 'Nociceptors', 'Rats', 'Rats, Inbred Strains', 'Reaction Time', 'Spinal Cord', 'Stress, Physiological', 'Swimming', 'Synaptic Transmission'] | 6,091,163 | [['A08.612.220'], ['B01.050'], ['F02.830.104', 'G11.561.035'], ['A08.186.211'], ['A05.360.319.679.256'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['A08.675.650.915.875', 'A08.800.950.875', 'A11.671.650.915.875'], ['B01.050.1... | ['Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Identifying human parieto-insular vestibular cortex using fMRI and cytoarchitectonic mapping. | The parieto-insular vestibular cortex (PIVC) plays a central role in the cortical vestibular network. Although this region was first defined and subsequently extensively studied in nonhuman primates, there is also ample evidence for a human analogue in the posterior parietal operculum. In this study, we functionally an... | ['Adult', 'Animals', 'Brain Mapping', 'Cerebral Cortex', 'Electric Stimulation', 'Functional Laterality', 'Humans', 'Macaca', 'Magnetic Resonance Imaging', 'Male', 'Parietal Lobe', 'Physical Stimulation', 'Postural Balance', 'Somatosensory Cortex', 'Vestibule, Labyrinth'] | 16,281,284 | [['M01.060.116'], ['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['E05.723.402'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.199.120.510'], ['E01.370.350.825.500'... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The initial United States experience with the ATS mechanical cardiac valve prosthesis. | From January 1, 1997 through June 30, 2000, 224 patients underwent valve replacement with the ATS Medical cardiac valve prosthesis under a USFDA-approved investigational device exemption study. Aortic valve replacement (AVR) was conducted in 152 patients (39 with coronary bypass) and mitral replacement (MVR) in 72 pati... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aortic Valve', 'Coronary Artery Bypass', 'Echocardiography', 'Endocarditis', 'Equipment Safety', 'Female', 'Follow-Up Studies', 'Heart Valve Diseases', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Postoperative Complications', 'Thromboembolism', 'Tr... | 11,803,148 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.541.510.110'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280.282'], ['E05.330'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. | Piwi proteins specify an animal-specific subclass of the Argonaute family that, in vertebrates, is specifically expressed in germ cells. We demonstrate that zebrafish Piwi (Ziwi) is expressed in both the male and the female gonad and is a component of a germline-specifying structure called nuage. Loss of Ziwi function ... | ['Animals', 'Embryo, Nonmammalian', 'Female', 'Genome', 'Germ Cells', 'Male', 'Ovary', 'RNA Interference', 'RNA, Untranslated', 'RNA-Binding Proteins', 'Retroelements', 'Testis', 'Zebrafish', 'Zebrafish Proteins'] | 17,418,787 | [['B01.050'], ['A13.350', 'A16.331'], ['G05.360.340'], ['A05.360.490', 'A11.497'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['G05.308.203.374.790'], ['D13.444.735.790'], ['D12.776.157.725', 'D12.776.664.962'], ['D13.444.308.760', 'G02.111.570.080.708.330.800', 'G05.360.080.708.330.800', 'G05.360.3... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the behavior of normal factor IX and the factor IX Bm variant Hilo in the prothrombin time test using tissue factors from bovine, human, and rabbit sources. | A subset of hemophilia B patients have a prolonged bovine-brain prothrombin time. These CRM+ patients are classified as having hemophilia Bm. The prolongation of the prothrombin time has been reported only with bovine brain (referred to as ox brain in some literature) as the source of thromboplastin; prothrombin times ... | ['Animals', 'Blood Coagulation', 'Cattle', 'Factor IX', 'Hemophilia B', 'Humans', 'Prothrombin Time', 'Rabbits', 'Thromboplastin'] | 8,352,232 | [['B01.050'], ['G09.188.390.150'], ['B01.050.150.900.649.313.500.380.271'], ['D08.622.355', 'D12.776.124.125.375', 'D12.776.811.243.355', 'D23.119.375'], ['C15.378.100.100.510', 'C15.378.100.141.510', 'C15.378.463.510', 'C16.320.099.510', 'C16.320.322.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.22... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Global practical tracking by output feedback for nonlinear systems with unknown growth rate and time delay. | This paper is the further investigation of work of Yan and Liu, 2011, and considers the global practical tracking problem by output feedback for a class of uncertain nonlinear systems with not only unmeasured states dependent growth but also time-varying time delay. Compared with the closely related works, the remarkab... | ['Algorithms', 'Computer Simulation', 'Feedback', 'Models, Theoretical', 'Neural Networks, Computer', 'Nonlinear Dynamics', 'Time Factors', 'Uncertainty'] | 25,276,859 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['L01.906.394.211'], ['E05.599'], ['G17.485', 'L01.224.050.375.605'], ['E05.599.850', 'H01.548.675'], ['G01.910.857'], ['E05.318.740.600.900', 'F02.463.785.373.820', 'G17.680.875', 'N05.715.360.750.625.850', 'N06.850.520.830.600.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Does MRSA affect patient outcomes in the elderly? A retrospective pilot study. | We retrospectively studied admissions to our geriatric acute assessment and rehabilitation ward over a one-year period, to identify those with Methicillin-resistant Staphylococcus aureus (MRSA) and determine whether this affected outcomes. Two hundred and thirty eight admissions of 204 patients were analysed and 9.8% o... | ['Aged', 'Aged, 80 and over', 'Comorbidity', 'Female', 'Humans', 'Length of Stay', 'Male', 'Methicillin Resistance', 'Mortality', 'Pilot Projects', 'Retrospective Studies', 'Scotland', 'Staphylococcal Infections'] | 10,860,695 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525', 'G07.690.773.984.269.347.500.600.525'], ['E05.318.308.985.550', 'N01.224.935.698', 'N... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Novel anticoagulant peptides from the functional site of human placental anticoagulant protein. | Histidine-containing peptides SHLRKV and DHTLIR, corresponding to placental anticoagulant protein-I (PAP-I) residues 204-209 and 266-271, respectively, are included in the functional site of PAP-I and exhibit anticoagulant activity, but the peptides in which alanine is substituted for histidine do not. However, the pep... | ['Amino Acid Sequence', 'Annexin A5', 'Anticoagulants', 'Binding Sites', 'Calcium-Binding Proteins', 'Female', 'Histidine', 'Humans', 'Molecular Sequence Data', 'Peptide Fragments', 'Pregnancy', 'Pregnancy Proteins', 'Sequence Homology, Nucleic Acid'] | 1,837,452 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.157.125.050.100'], ['D27.505.954.502.119'], ['G02.111.570.120'], ['D12.776.157.125'], ['D12.125.072.329', 'D12.125.142.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D12.644.541'], ['G08.686.784.769'], ['D12.776.780'], ['G02.111.810.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Attachment of the anteroinferior glenohumeral ligament-labrum complex to the glenoid: an anatomic study. | PURPOSE: To determine the morphology of the attachment of the anteroinferior glenohumeral ligament-labrum complex (AIGHL-LC) to the anterior rim of the glenoid.METHODS: Sixty-six cadaveric shoulders with a mean age of 81 years were studied. The length of the AIGHL-LC attachment in the superoinferior direction and its d... | ['Aged', 'Aged, 80 and over', 'Cadaver', 'Cartilage, Articular', 'Female', 'Humans', 'Ligaments, Articular', 'Male', 'Shoulder Joint'] | 23,107,249 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.260.224'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['A02.835.583.748']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Utilization of waste fish oil and glycerol as carbon sources for polyhydroxyalkanoate production by Salinivibrio sp. M318. | A moderately halophilic bacterium isolated from fermenting shrimp paste, Salinivibrio sp. M318 was found capable of using fish sauce and mixtures of waste fish oil and glycerol as nitrogen and carbon sources, respectively, for poly(3-hydroxybutyrate) (PHB) production. A cell dry weight (CDW) of up to 10 g/L and PHB con... | ['Biotransformation', 'Carbon', 'Fatty Acids', 'Fermentation', 'Fish Oils', 'Glycerol', 'Molecular Structure', 'Nitrogen', 'Polyhydroxyalkanoates', 'Vibrionaceae', 'Waste Disposal, Fluid'] | 31,513,855 | [['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D01.268.150'], ['D10.251'], ['G02.111.158.249', 'G03.191.249'], ['D10.627.430'], ['D02.033.800.875.500', 'D09.853.875.500'], ['G02.111.570', 'G02.466'], ['D01.268.604', 'D01.362.625'], ['D05.750.078.789', 'D05.750.728.890', 'D10.751'], ['B03.440.450.900', 'B03.660.250.8... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Soil mites of the families Ascidae, Blattisociidae and Melicharidae (Acari: Mesostigmata) from mountainous areas of Colombia. | Soil mites of the Ascidae sensu Lindquist & Evans (1965) are poorly known in Colombia. This group, presently represented by the families Ascidae sensu stricto, Blattisociidae and Melicharidae, contains species known to prey on small arthropods and nematodes, thus having the potential to be used for the control of soil ... | ['Animals', 'Colombia', 'Female', 'Mites', 'Soil', 'Species Specificity'] | 27,395,637 | [['B01.050'], ['Z01.107.757.284'], ['B01.050.500.131.166.132.419'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G16.824']] | ['Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Management of failed primary intervention for ureteropelvic junction obstruction: 12-year, single-center experience. | OBJECTIVES: To compare contemporary endourologic and open surgical management of failed primary intervention for ureteropelvic junction obstruction, specifically in regard to immediate and long-term results and complications.METHODS: Since 1989, 48 patients have undergone management of failed primary intervention for u... | ['Adolescent', 'Adult', 'Aged', 'Endoscopy', 'Female', 'Follow-Up Studies', 'Hospitalization', 'Humans', 'Kidney Pelvis', 'Length of Stay', 'Male', 'Middle Aged', 'Reoperation', 'Treatment Failure', 'Ureteral Obstruction', 'Urologic Surgical Procedures'] | 12,597,933 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.388.250', 'E04.502.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.537'], ['E02.760.400.480', 'N02.421.58... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pre-operative dysglycemia is associated with decreased survival in patients with pancreatic neuroendocrine neoplasms. | BACKGROUND: Diabetes mellitus is associated with increased risk of pancreatic cancer and impaired postresection survival. For pancreatic neuroendocrine neoplasms, no evidence is available for a similar effect of diabetes mellitus. The aim of this study was to evaluate the glycemic profile in patients with pancreatic ne... | ['Aged', 'Blood Glucose', 'Diabetes Mellitus', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Glycated Hemoglobin A', 'Humans', 'Hyperglycemia', 'Hypoglycemic Agents', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Neuroendocrine Tumors', 'Pancreatectomy', 'Pancreatic Neoplasms', 'Preoperative Period', 'Pro... | 31,889,543 | [['M01.060.116.100'], ['D09.947.875.359.448.500'], ['C18.452.394.750', 'C19.246'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transient cellular structures in developing corpus callosum of the human brain. | The corpus callosum connects two cerebral hemispheres as the most voluminous fiber system in the human brain. The developing callosal fibers originate from immature pyramidal neurons, grow through complex pathways and cross the midline using different substrates in transient fetal structures. We analyzed cellular struc... | ['Adult', 'Cadaver', 'Child', 'Corpus Callosum', 'Female', 'Human Development', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Neural Pathways'] | 16,848,154 | [['M01.060.116'], ['C23.550.260.224'], ['M01.060.406'], ['A08.186.211.200.885.800.750'], ['F01.525', 'G07.345.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['A08.612']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Demographic, environmental, access, and attitude factors that influence walking to school by elementary school-aged children. | BACKGROUND: Walking to school has been identified as an activity that contributes to children's daily exercise requirements. The purpose of this study was to better understand factors that influence walking to school by elementary school-aged children.METHODS: A sample of 1,897 elementary school-aged children (84% resp... | ['Adolescent', 'Age Factors', 'Attitude', 'Child', 'Demography', 'Environment', 'Female', 'Humans', 'Male', 'Schools', 'Sex Factors', 'Socioeconomic Factors', 'Walking'] | 19,432,865 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.100'], ['M01.060.406'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.783', 'J03.832'], ['N05.715.350.675', 'N06.850.490.875'], ['I01.880.853.996', 'N01.824'], ['G11.427.410.56... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Functional characterization of Aspergillus nidulans ypkA, a homologue of the mammalian kinase SGK. | The serum- and glucocorticoid-regulated protein kinase (SGK) is an AGC kinase involved in signal cascades regulated by glucocorticoid hormones and serum in mammals. The Saccharomyces cerevisiae ypk1 and ypk2 genes were identified as SGK homologues and Ypk1 was shown to regulate the balance of sphingolipids between the ... | ['Acyl Coenzyme A', 'Aspergillus nidulans', 'Catalysis', 'Cell Membrane', 'Endocytosis', 'Fungal Proteins', 'Gene Expression Profiling', 'Gene Expression Regulation, Fungal', 'Green Fluorescent Proteins', 'Immediate-Early Proteins', 'Multigene Family', 'Mutation', 'Phenotype', 'Protein-Serine-Threonine Kinases', 'Sacch... | 23,472,095 | [['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['B01.300.381.081.420'], ['G02.130'], ['A11.284.149'], ['G04.417'], ['D12.776.354'], ['E05.393.332'], ['G05.308.330'], ['D12.776.532.265'], ['D12.776.460', 'D12.776.964.925.968'], ['G05.360.340.024.340.645'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Saxatilin, a snake venom disintegrin, suppresses TNF-alpha-induced ovarian cancer cell invasion. | Saxatilin is a disintegrin known to inhibit tumor progression in vivo and in vitro. The role of saxatilin in cancer cell invasion was examined by a modified Boyden chamber assay in MDAH 2774 human ovarian cancer cell line. Saxatilin (50 nM) significantly inhibited cancer cell invasion induced by tumor necrosis factor-a... | ['Animals', 'Cell Line, Tumor', 'Disintegrins', 'Female', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Matrix Metalloproteinase 9', 'Neoplasm Invasiveness', 'Ovarian Neoplasms', 'Snake Venoms', 'Tumor Necrosis Factor-alpha'] | 17,394,781 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.138'], ['G05.308.320'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.480.205.360', 'D08.811.277.656.300.480.252.445', 'D08.811.277.656.300.480.525.700.350', 'D08.811.277.656.675.374.205.360', 'D08.811.277.656.675.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Stage IV small cell esophageal carcinoma that responded to various chemotherapeutic regimens with relative longevity - a case report]. | Small cell carcinoma of the esophagus is reported to be both rare and aggressive, and is commonly associated with a short post-diagnosis survival period. We report a case of Stage IV small cell carcinoma of the esophagus involving a relatively long survival period of 2 years. The patient was a 70-year-old man with a ch... | ['Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Small Cell', 'Esophageal Neoplasms', 'Fatal Outcome', 'Humans', 'Male', 'Neoplasm Staging', 'Tomography, X-Ray Computed'] | 25,731,409 | [['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200.380'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Drake Chemical Workers' Health Registry Study: I. Notification and medical surveillance of a group of workers at high risk of developing bladder cancer. | A medical surveillance program and epidemiologic study of 408 former workers of the Drake Chemical Company (now a Superfund waste site) was established in 1986. The Drake Health Registry Study was initiated because these workers had probable past exposures to beta-naphthylamine (BNA), a potent bladder carcinogen. The r... | ['2-Naphthylamine', 'Adult', 'Cause of Death', 'Chemical Industry', 'Cohort Studies', 'Female', 'Humans', 'Incidence', 'Male', 'Mass Screening', 'Middle Aged', 'Occupational Diseases', 'Occupational Exposure', 'Pennsylvania', 'Population Surveillance', 'Prevalence', 'Registries', 'Survival Rate', 'Urinary Bladder Neopl... | 2,008,919 | [['D02.092.710', 'D02.455.426.559.847.638.850', 'D04.615.638.850'], ['M01.060.116'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['J01.576.655.437'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Adolescents' weight, sex, and family functioning. | The study explored family functioning with adolescents of varying weight. The participants were 572 adolescents (286 boys and 286 girls) (M = 15.7 years, SD = 1.04) who comprised four weight groups: underweight (less than 90% expected weight), normal weight (90 to 110%), overweight (111 to 125%), and obese (over 125%).... | ['Adolescent', 'Body Weight', 'Family', 'Feeding Behavior', 'Female', 'Humans', 'Male', 'Psychology, Adolescent', 'Sex Factors'] | 7,894,456 | [['M01.060.057'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['F01.829.263', 'I01.880.853.150'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.096.628.065'], ['N05.715.350.675', 'N06... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Electron Bifurcation: Thermodynamics and Kinetics of Two-Electron Brokering in Biological Redox Chemistry. | How can proteins drive two electrons from a redox active donor onto two acceptors at very different potentials and distances? And how can this transaction be conducted without dissipating very much energy or violating the laws of thermodynamics? Nature appears to have addressed these challenges by coupling thermodynami... | ['Electrons', 'Kinetics', 'Oxidation-Reduction', 'Thermodynamics'] | 28,876,046 | [['G01.249.335', 'G01.358.500.750'], ['G01.374.661', 'G02.111.490'], ['G02.700', 'G03.295.531'], ['G01.906']] | ['Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification and quantification of the major volatile constituents in antidepressant active fraction of xiaoyaosan by gas chromatography-mass spectrometry. | ETHNOPHARMACOLOGICAL RELEVANCE: Xiaoyaosan (XYS), a well-known formula for relieving depression, was originated from the book of "Taiping Huimin Heji Jufang" in Song Dynasty (960-1127 AD), composed of Radix Bupleuri, Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae, Poria, Herba Menthae... | ['4-Butyrolactone', 'Animals', 'Antidepressive Agents', 'Behavior, Animal', 'Depression', 'Disease Models, Animal', 'Drugs, Chinese Herbal', 'Gas Chromatography-Mass Spectrometry', 'Lactones', 'Male', 'Mice', 'Mice, Inbred ICR', 'Molecular Structure', 'Motor Activity', 'Palmitic Acid', 'Phytotherapy', 'Plants, Medicina... | 22,366,681 | [['D02.540.150', 'D03.383.312.150'], ['B01.050'], ['D27.505.954.427.700.122'], ['F01.145.113'], ['F01.145.126.350'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D20.215.784.500.350', 'D26.335'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D02.540'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Image-guided, lobe-specific hydrodynamic gene delivery to swine liver. | Image-guided, lobe-specific hydrodynamic gene delivery to liver was assessed in pigs. The procedure involved image-guided insertion of a balloon catheter to the hepatic vein of the selected lobe from the jugular vein and hydrodynamic injection of plasmid DNA using a newly developed computer-controlled injection device.... | ['Animals', 'Injections', 'Liver', 'Substrate Specificity', 'Swine', 'Transgenes', 'Water'] | 19,156,134 | [['B01.050'], ['E02.319.267.530'], ['A03.620'], ['G02.111.835'], ['B01.050.150.900.649.313.500.880'], ['G05.360.340.024.340.825'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term effects of parathyroidectomy on hypertension prevalence and circadian blood pressure profile in primary hyperparathyroidism. | Our aims were to evaluate the prevalence and outcome of hypertension in patients with primary hyperparathyroidism (PHPT), previously and after follow-up of parathyroidectomy. A group of 46 consecutive patients with sporadic PHPT due to adenoma undergoing surgery were followed an average of 3.5 years (range 36 to 53 mon... | ['Adult', 'Aged', 'Aged, 80 and over', 'Argentina', 'Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'Calcium', 'Circadian Rhythm', 'Creatinine', 'Female', 'Follow-Up Studies', 'Humans', 'Hyperparathyroidism, Primary', 'Hypertension', 'Male', 'Middle Aged', 'Parathyroid Hormone', 'Parathyroidectomy', 'Prevale... | 20,504,122 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.757.077'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G07.180.562.190'], ['D03.383.129.308.207'], ['E05.318.372.500.750.249', 'N05.715.360.3... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Latency of saccadic eye movement during contraction of bilateral and unilateral shoulder girdle elevators. | We compared the timed latencies of saccadic eye movement during isometric contraction of the bilateral and unilateral shoulder girdle elevators in a sitting posture. Muscle contraction force was increased in 10% increments from 0% to 60% of the maximal voluntary contraction (MVC) of each side. Saccadic latency was meas... | ['Adolescent', 'Adult', 'Electromyography', 'Female', 'Functional Laterality', 'Humans', 'Isometric Contraction', 'Male', 'Psychophysiology', 'Reaction Time', 'Reference Values', 'Saccades', 'Shoulder'] | 12,705,524 | [['M01.060.057'], ['M01.060.116'], ['E01.370.405.255', 'E01.370.530.255'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['E02.190.525.812', 'F02.830', 'F04.096.795', 'H01.158.782.795'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['E05.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Constitutive heterochromatin in early embryogenesis of Drosophila melanogaster. | The formation of constitutive heterochromatin was studied during the embryonic development of Drosophila melanogaster, using the C-banding technique. During embryonic cleavage, C-banded material is not seen in mitotic chromosomes; the differentiation between euchromatin and heterochromatin only occurs at blastoderm. Th... | ['Animals', 'Chromosome Banding', 'Drosophila melanogaster', 'Heterochromatin', 'Karyotyping', 'Mitosis'] | 1,921,980 | [['B01.050'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E05.242.385.130', 'E05.393.285.130'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['A11.284.430.106.279.345.190.160.180.383', 'D1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of remote stimulation on the mean firing rate of cat retinal ganglion cells. | Visual stimulation outside the classical receptive field can have pronounced effects on cat retinal ganglion cells. We characterized the effects of such stimulation by varying the contrast, spatial frequency, temporal frequency, and spatial extent of remote drifting sinusoidal gratings. We found that the mean firing ra... | ['Action Potentials', 'Animals', 'Cats', 'Contrast Sensitivity', 'Male', 'Microelectrodes', 'Models, Neurological', 'Motion Perception', 'Photic Stimulation', 'Retinal Ganglion Cells', 'Time Factors', 'Visual Fields', 'Visual Pathways'] | 11,466,451 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['E07.305.250.500'], ['E05.599.395.642'], ['F02.463.593.932.567'], ['E05.723.729'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upregulation of endothelin-1 and adrenomedullin gene expression in the mouse endotoxin shock model. | Septic shock is a life-threatening disorder caused by lipopolysaccharide (LPS) and other bacterial products. Accumulating evidence indicates a role for vasoactive substances and cytokines in this disease process. In this study we examined the effect of LPS on the gene expression of endothelin-1 (ET-1) and adrenomedulli... | ['Adrenomedullin', 'Animals', 'Blotting, Northern', 'Endothelin-1', 'Endotoxins', 'Enzyme-Linked Immunosorbent Assay', 'Galactosamine', 'Lipopolysaccharides', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Peptides', 'RNA', 'Shock, Septic', 'Up-Regulation'] | 9,595,537 | [['D06.472.699.077', 'D12.644.548.017'], ['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['D23.946.123.329'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D09.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Correlation of serum sex hormone levels with metabolic syndrome in elderly men]. | OBJECTIVE: To investigate the relationship between sex hormones and metabolic syndrome (MS), as well as its components in elderly men.METHODS: 1 505 elderly men (?60 years old, mean age 75.4±9.7 years old) who participated in a routine health screening examination in PLA general hospital from May to June in 2012 were e... | ['Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Dyslipidemias', 'Humans', 'Hyperglycemia', 'Male', 'Metabolic Syndrome', 'Obesity', 'Odds Ratio', 'Overweight', 'Prevalence', 'Risk Factors', 'Sex Hormone-Binding Globulin', 'Testosterone'] | 27,055,508 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.584.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ['C18.452.394.968.500.570', 'C18.452.625'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Comparative effect of sydnocarb and phenamin on the bioelectrical activity of the brain]. | In tests with cats and rabbits sydnocarb in doses of 3,4-8.5-17 mg/kg (per os or intraperitoneally) produces a more lasting reticulo-cortical activation than does amphetamine used in respectively equimolecular amounts. According to the EEG finding there is also observed a substantial difference in the nature of interac... | ['Amphetamine', 'Animals', 'Antidepressive Agents', 'Brain', 'Cats', 'Cerebral Cortex', 'Chlorpromazine', 'Dose-Response Relationship, Drug', 'Electric Stimulation', 'Electroencephalography', 'Electrophysiology', 'Evoked Potentials', 'Imines', 'Imipramine', 'Oxadiazoles', 'Photic Stimulation', 'Rabbits', 'Receptors, Ad... | 1,227,898 | [['D02.092.471.683.152.110'], ['B01.050'], ['D27.505.954.427.700.122'], ['A08.186.211'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.200.885.287.500'], ['D02.886.369.198', 'D03.633.300.783.198'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.723.402'], ['E01.370.376.300', 'E01.370.405.245'], ['H01.15... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Intramolecular coupling of active sites in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. | The intramolecular passage of substrate between the component enzymes of the pyruvate dehydrogenase multienzyme complex of Escherichia coli was examined. A series of partly reassembled complexes, varying only in their E1 (pyruvate decarboxylase, EC 1.2.4.1) content, was incubated with pyruvate in the absence of CoA, co... | ['Binding Sites', 'Chemical Phenomena', 'Chemistry', 'Escherichia coli', 'Ethylmaleimide', 'Kinetics', 'Pyruvate Dehydrogenase Complex'] | 367,364 | [['G02.111.570.120'], ['G02'], ['H01.181'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.241.081.337.502.524.418', 'D02.478.440.418', 'D03.383.129.578.399.418'], ['G01.374.661', 'G02.111.490'], ['D05.500.562.625', 'D08.811.600.741']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Isolation of a Helicobacter pylori protein, FldA, associated with mucosa-associated lymphoid tissue lymphoma of the stomach. | BACKGROUND & AIMS: The growth of gastric mucosa-associated lymphoid tissue lymphoma (MALToma) seems to depend on the stimulation of Helicobacter pylori. We attempted to identify specific antigen(s) from H. pylori strains associated with MALToma.METHODS: Membranous and secreted proteins of H. pylori were compared on sod... | ['Adult', 'Aged', 'Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Blotting, Western', 'Electrophoresis, Gel, Two-Dimensional', 'Female', 'Flavoproteins', 'Humans', 'Lymphoma, B-Cell, Marginal Zone', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Stomach Neoplasms'] | 10,381,913 | [['M01.060.116'], ['M01.060.116.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.401.250', 'E05.301.300.230'], ['D12.776.331'], ['B... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[A life-threatening anaphylactic reaction following mannitol]. | CASE REPORT: After uneventful induction of general anesthesia, severe hypotension and cardiac arrest developed in a 39-year-old, non-atopic man following infusion of 20% mannitol 80 min after the beginning of anesthesia. It caused a systolic blood pressure of 40 mmHg during a period of 10 min and tachycardia followed b... | ['Adult', 'Anaphylaxis', 'Humans', 'Male', 'Mannitol', 'Resuscitation'] | 1,570,884 | [['M01.060.116'], ['C20.543.480.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.800.609', 'D09.853.609'], ['E02.365.647']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Finite element analysis of the influence of anchorage number and location on Bankart repair strength of shoulder joint]. | OBJECTIVE: To study the influence of the number and position of anchor nails on the Bankart repair by the finite element analysis.METHODS: The 3D CT data of shoulder joints including normal adult volunteers were imported into Mimics 10.0 and Geomagic 2012 software to reconstruct the related tissues, and then meshed in ... | ['Biomechanical Phenomena', 'Cadaver', 'Finite Element Analysis', 'Humans', 'Joint Instability', 'Shoulder Dislocation', 'Shoulder Joint'] | 30,583,654 | [['G01.154.090', 'G01.374.089'], ['C23.550.260.224'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['C05.550.518.750', 'C26.289.750', 'C26.803.125'], ['A02.835.583.748']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthetic remodeling of the chartreusin pathway to tune antiproliferative and antibacterial activities. | Natural products of the benzonaphthopyranone class, such as chartreusin, elsamicin A, gilvocarcin, and polycarcin, represent potent leads for urgently needed anticancer therapeutics and antibiotics. Since synthetic protocols for altering their architectures are limited, we harnessed enzymatic promiscuity to generate a ... | ['Anti-Bacterial Agents', 'Antineoplastic Agents', 'Benzopyrans', 'Cell Line, Tumor', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Drug Screening Assays, Antitumor', 'Enterococcus', 'Glycosides', 'HT29 Cells', 'HeLa Cells', 'Humans', 'K562 Cells', 'Methicillin-Resistant Staphylococcus aureus', 'Microbial ... | 24,143,864 | [['D27.505.954.122.085'], ['D27.505.954.248'], ['D03.383.663.283', 'D03.633.100.150'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B03.353.750.250.250', 'B03.510.55... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A structured participatory method to support policy option analysis in a social-ecological system. | In this study we demonstrate how to support policy option analysis for a problematic Social-Ecological System (SES) with the help of stakeholder participation. SES sustainability problems 1) are highly complex, 2) may lack reliable data, 3) encompass conflicting interests and 4) may require contradictory management int... | ['Ecosystem', 'Environmental Policy', 'Iran'] | 28,407,599 | [['G16.500.275.157', 'N06.230.124'], ['I01.655.500.608.180', 'I01.880.604.825.608.180', 'N03.623.500.608.180', 'N06.230.204'], ['Z01.252.245.500.350']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Staff's attitudes to the use of restraint and seclusion in a Norwegian university psychiatric hospital. | A questionnaire-based study examining the experiences and attitudes of staff to restraint and seclusion in a Norwegian university psychiatric hospital demonstrated that a majority of staff believed the interventions were used correctly. Staff at wards with high usage of restraint and seclusion, and male staff, were mos... | ['Adult', 'Aggression', 'Attitude of Health Personnel', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Inservice Training', 'Male', 'Middle Aged', 'Norway', 'Patient Care Team', 'Patient Isolation', 'Psychiatric Department, Hospital', 'Restraint, Physical', 'Self-Injurious Behavior', 'Violence'] | 14,630,551 | [['M01.060.116'], ['F01.145.126.125', 'F01.145.813.045'], ['F01.100.050', 'N05.300.100'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['M01.060.116.630'], ['Z01.542.816.374'], ['N04.590.715'], ['E02.770', 'N06.850.780.200.450.650'], ['N02.278.216.500.968.641', '... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Genetic Screening of Anderson-Fabry Disease in Probands Referred From Multispecialty Clinics. | BACKGROUND: Anderson-Fabry disease (AFD) is a rare X-linked lysosomal storage disease, caused by defects of the alpha-galactosidase A (GLA) gene. AFD can affect the heart, brain, kidney, eye, skin, peripheral nerves, and gastrointestinal tract. Cardiology (hypertrophic cardiomyopathy), neurology (cryptogenic stroke), a... | ['Adolescent', 'Adult', 'Child', 'Fabry Disease', 'Female', 'Genetic Testing', 'Hospitals', 'Humans', 'Male', 'Medicine', 'Middle Aged', 'Mutation', 'Prospective Studies', 'alpha-Galactosidase'] | 27,585,509 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C10.228.140.163.100.435.825.200', 'C10.228.140.300.275.374', 'C14.907.253.329.374', 'C16.320.322.124', 'C16.320.565.189.435.825.200', 'C16.320.565.398.641.803.300', 'C16.320.565.595.554.825.200', 'C18.452.132.100.435.825.200', 'C18.452.584.687.803.300', 'C18.452.648... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Cardiac troponin I assessment and late cardiac complications after carotid stenting or endarterectomy. | PURPOSE: When compared with carotid endarterectomy (CEA), percutaneous carotid angioplasty with stent replacement (CAS) is a less invasive technique in the treatment of carotid stenosis. However, periprocedural hemodynamic instability still remains a challenge. This instability might lead to myocardial damage, which is... | ['Aged', 'Biomarkers', 'Blood Vessel Prosthesis Implantation', 'Carotid Stenosis', 'Electrocardiography', 'Endarterectomy, Carotid', 'Female', 'Fluoroimmunoassay', 'Follow-Up Studies', 'Humans', 'Male', 'Myocardial Infarction', 'Myocardium', 'Postoperative Complications', 'Prospective Studies', 'Risk Factors', 'Stents'... | 15,886,658 | [['M01.060.116.100'], ['D23.101'], ['E04.100.814.868.500', 'E04.650.200'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E04.100.814.456.250'], ['E01.370.225.500.607.512.240.655', 'E01.370.225.750.551.512.240.655', 'E05.200.500.607.512.240.655', 'E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
From work-related stress evaluation to organizational wellbeing promotion: the case of an Italian pharmaceutical company. | BACKGROUND: Work-related stress evaluation is a legal requirement for companies that, in some cases, might be seen as an opportunity to examine wellbeing at work and the dimensions related to it, through the involvement of employees. To that end, this study considers the job demands-resources model as a theoretical fra... | ['Adult', 'Drug Industry', 'Female', 'Humans', 'Italy', 'Job Satisfaction', 'Male', 'Middle Aged', 'Occupational Health', 'Occupational Stress', 'Workload'] | 27,681,568 | [['M01.060.116'], ['J01.576.655.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['F02.784.692.425'], ['M01.060.116.630'], ['N01.400.525'], ['C24.580', 'F01.145.126.990.734', 'F02.830.900.666'], ['I03.946.225.500', 'N04.452.677.650.500']] | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Calprotectin levels in rheumatoid arthritis and their correlation with disease activity: a meta-analysis. | OBJECTIVE: We evaluated the relationship between calprotectin levels and rheumatoid arthritis (RA), and the correlation between plasma/serum calprotectin and RA activity.METHODS: We searched PUBMED, EMBASE, and Cochrane databases and performed meta-analyses comparing plasma/serum or synovial fluid calprotectin levels i... | ['Arthritis, Rheumatoid', 'Biomarkers', 'Humans', 'Leukocyte L1 Antigen Complex', 'Severity of Illness Index'] | 28,425,837 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D23.101'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.125.750.500', 'D12.776.631.655.500', 'D23.050.301.562'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Thresholds for sensing foot dorsi- and plantarflexion during upright stance: effects of age and velocity. | BACKGROUND: The objective of this study was to determine in healthy young and old adult females the influence of age, rotation direction, angle, and speed on the threshold for sensing foot dorsi- and plantarflexion when standing and bearing weight on the limb.METHODS: Twelve young (YF, mean age 22 years) and 12 old (OF... | ['Adult', 'Aged', 'Aging', 'Analysis of Variance', 'Ankle Joint', 'Fatigue', 'Female', 'Foot', 'Humans', 'Logistic Models', 'Movement', 'Muscle Contraction', 'Muscle, Skeletal', 'Posture', 'Proprioception', 'Rotation', 'Sensory Thresholds', 'Weight-Bearing'] | 9,467,431 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A02.835.583.378.062'], ['C23.888.369'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.83... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Treatment during primary HIV infection does not lower viral set point but improves CD4 lymphocytes in an observational cohort. | OBJECTIVE: To investigate if early treatment of primary HIV-1 infection (PHI) reduces viral set point and/or increases CD4 lymphocytes.METHODS: Analysis of two prospective multi-centre PHI cohorts. HIV-1 RNA and CD4 lymphocytes in patients with transient treatment were compared to those in untreated patients. Time to C... | ['Adolescent', 'Adult', 'Antiretroviral Therapy, Highly Active', 'CD4 Lymphocyte Count', 'Cohort Studies', 'Female', 'HIV Infections', 'HIV Seropositivity', 'HIV-1', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Multicenter Studies as Topic', 'Outcome Assessment, Health Care', 'Proportional Hazards Models'... | 19,661,009 | [['M01.060.057'], ['M01.060.116'], ['E02.319.310.075'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['E05.318.372.500.750', 'N05.715.360.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Traumatic dislocation of the first metatarsophalangeal joint with tibial sesamoid fracture: a case report of a type III B dislocation. | We present a case report about traumatic dislocation of the first metatarsophalangeal joint and patterns of injury. We are unaware of previous reports in the literature describing this unusual variant. | ['Adult', 'Female', 'Humans', 'Joint Dislocations', 'Metatarsophalangeal Joint', 'Sesamoid Bones', 'Tibial Fractures'] | 18,347,126 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['A02.835.583.378.531'], ['A02.835.232.730'], ['C26.404.875', 'C26.558.857']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transplacental immunity and waning of maternal antibody in measles. | Since transplacental immunity and waning of maternally derived measles specific antibodies play an important role in determining the optimum age for vaccination of infants against measles, a study was carried out in which 150 paired samples and 581 infant serum samples were tested for measles specific antibodies. Out o... | ['Age Distribution', 'Female', 'Humans', 'Immunity, Maternally-Acquired', 'Immunization Schedule', 'Infant', 'Infant, Newborn', 'Longitudinal Studies', 'Measles', 'Measles Vaccine', 'Pregnancy', 'Regression Analysis', 'Serologic Tests'] | 10,829,850 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.570'], ['E02.095.465.425.400.470', 'E05.478.550.545'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['C01.925.782.580.600... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Adherence to waiting-time targets for pediatric nephrology clinic referrals. | Waiting times for specialist consultation have not been adequately studied, especially in the pediatric population. The aim of this study was to determine the extent to which pediatric nephrology subspecialty clinic referral waiting times are adhered to with regard to previously determined access targets. Referrals to ... | ['Adolescent', 'Appointments and Schedules', 'Canada', 'Child', 'Child, Preschool', 'Female', 'Health Services Accessibility', 'Humans', 'Infant', 'Kidney Diseases', 'Male', 'Nephrology', 'Pediatrics', 'Referral and Consultation', 'Retrospective Studies', 'Time Factors', 'Waiting Lists'] | 19,937,350 | [['M01.060.057'], ['N04.452.095'], ['Z01.107.567.176'], ['M01.060.406'], ['M01.060.406.448'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C12.777.419', 'C13.351.968.419'], ['H02.403.429.580'], ['H02.403.670'], ['N04.452.758.849'], ['E05.318.372.500.500.500', '... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Injury incidence in elite youth field hockey players at the 2016 European Championships. | Despite being an essential consideration when deciding rule changes, injury prevention strategies, and athlete development models, there is little epidemiological data of U18 field hockey player injuries-something explicitly referred to in the 2015 International Olympic Committee's Consensus Statement on Youth Athlete ... | ['Athletes', 'Athletic Injuries', 'Europe', 'Female', 'Hockey', 'Humans', 'Incidence', 'Male', 'Personal Protective Equipment'] | 30,138,463 | [['M01.072'], ['C26.115'], ['Z01.542'], ['I03.450.642.845.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E07.700.560', 'J01.637.708.560']] | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Initial experience with same day discharge after laparoscopic appendectomy for nonperforated appendicitis. | BACKGROUND: Although many laparoscopic procedures are performed on an outpatient basis, patients who have undergone a laparoscopic appendectomy have typically stayed at least overnight. Recently, data in both the pediatric and adult literature suggest that same day discharge (SDD) for acute nonperforated appendicitis i... | ['Adolescent', 'Ambulatory Surgical Procedures', 'Appendectomy', 'Appendicitis', 'Child', 'Female', 'Humans', 'Laparoscopy', 'Male', 'Postoperative Care', 'Retrospective Studies'] | 24,725,679 | [['M01.060.057'], ['E04.030'], ['E04.210.078'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['E05.318.372.500.500.500', 'E05.318.372.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cinnamon improves metabolic factors without detectable effects on adiponectin in women with polycystic ovary syndrome. | BACKGROUND AND OBJECTIVES: The objectives of this study were to investigate the effects of cinnamon supplementation on glycemic indices, serum lipids and adiponectin in patients with polycystic ovary syndrome (PCOS).METHODS AND STUDY DESIGN: This double-blind randomized controlled clinical trial was conducted on 84 ove... | ['Adiponectin', 'Adult', 'Cinnamomum zeylanicum', 'Double-Blind Method', 'Female', 'Homeostasis', 'Humans', 'Insulin', 'Insulin Resistance', 'Lipids', 'Polycystic Ovary Syndrome', 'Young Adult'] | 29,737,802 | [['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['M01.060.116'], ['B01.650.940.800.575.912.250.595.400.149.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A method for generating natural-sounding speech stimuli for cognitive brain research. | OBJECTIVE: In response to the rapidly increasing interest in using human voice in cognitive brain research, a new method, semisynthetic speech generation (SSG), is presented for generation of speech stimuli.METHODS: The method synthesizes speech stimuli as a combination of purely artificial processes and processes that... | ['Humans', 'Models, Neurological', 'Speech', 'Speech Perception'] | 10,454,267 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.642'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['F02.463.593.071.875', 'G07.888.125.875']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Land use regression model for ultrafine particles in Amsterdam. | There are currently no epidemiological studies on health effects of long-term exposure to ultrafine particles (UFP), largely because data on spatial exposure contrasts for UFP is lacking. The objective of this study was to develop a land use regression (LUR) model for UFP in the city of Amsterdam. Total particle number... | ['Air Pollutants', 'Air Pollution', 'Cities', 'Environmental Exposure', 'Environmental Monitoring', 'Geographic Information Systems', 'Linear Models', 'Netherlands', 'Particle Size', 'Particulate Matter'] | 21,158,386 | [['D27.888.284.101'], ['N06.850.460.100'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['L01.313.500.750.300.314', 'L01.470.750.750.462'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance. | BACKGROUND: An important virulence mechanism of the malaria parasite Plasmodium falciparum is cytoadhesion, the binding of infected erythrocytes to endothelial cells in the second half of asexual blood stage development. Conventional methods to investigate adhesion of infected erythrocytes are mostly performed under st... | ['CD36 Antigens', 'Cell Adhesion', 'Chondroitin Sulfates', 'Erythrocytes', 'Humans', 'Plasmodium falciparum', 'Quartz Crystal Microbalance Techniques'] | 27,296,675 | [['D12.776.157.530.300.500', 'D12.776.395.550.625.136', 'D12.776.543.550.625.136', 'D12.776.543.585.300.500', 'D12.776.543.750.011', 'D12.776.543.750.705.675.136', 'D12.776.543.750.705.940.625.249', 'D12.776.543.750.710.450.750.625.249'], ['G04.022'], ['D09.698.373.200.300'], ['A11.118.290', 'A11.443.240', 'A15.145.229... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insulin-like growth factor-I gene expression during development and estrous cycle in the rat uterus. | The ontogeny and estrous cycle-dependent variation of insulin-like growth factor-I (IGF-I) gene expression was analyzed in the rat uterus. RNA extracted from rat uteri contained transcripts with estimated sizes of 7.0, 1.7, and 1.2-0.8 kb that were recognized by a 32P-labelled mouse IGF-I RNA probe. A solution hybridiz... | ['Aging', 'Animals', 'Blotting, Northern', 'Estradiol', 'Estrus', 'Female', 'Gene Expression Regulation', 'Hypophysectomy', 'Insulin-Like Growth Factor I', 'Kinetics', 'Rats', 'Rats, Inbred Strains', 'Uterus'] | 1,816,001 | [['G07.345.124'], ['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.195.500'], ['G05.308'], ['E04.270.532', 'E04.525.400'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['G01.374.661', 'G02.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glucocorticoid receptor isoforms alpha and beta in in vitro cytokine-induced glucocorticoid insensitivity. | We stimulated peripheral blood mononuclear cells from 14 healthy subjects, 14 patients with stable asthma, and 13 patients with unstable asthma with interleukin (IL)-2 and IL-4 to induce glucocorticoid insensitivity and we examined the relationship between insensitivity and the expression of glucocorticoid receptor (GR... | ['Adult', 'Asthma', 'Cytokines', 'Dexamethasone', 'Female', 'Glucocorticoids', 'Humans', 'In Vitro Techniques', 'Interleukin-2', 'Interleukin-4', 'Lymphocytes', 'Male', 'Monocytes', 'Protein Isoforms', 'Receptors, Glucocorticoid', 'Reverse Transcriptase Polymerase Chain Reaction'] | 15,184,204 | [['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.6... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identifying the effects of microsaccades in tripolar EEG signals. | Microsaccades are tiny, involuntary eye movements that occur during fixation, and they are necessary to human sight to maintain a sharp image and correct the effects of other fixational movements. Researchers have theorized and studied the effects of microsaccades on electroencephalography (EEG) signals to understand a... | ['Electroencephalography', 'Eye Movements', 'Humans', 'Movement'] | 29,060,811 | [['E01.370.376.300', 'E01.370.405.245'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tongue Pressure Production and Submental Surface Electromyogram Activities During Tongue-Hold Swallow with Different Holding Positions and Tongue Length. | Our previous study regarding the tongue-hold swallow (THS) demonstrated that the tongue-to-palate contact during THS could be influenced by the maximum tongue protrusion length (MTPL) of individual subjects, resulting in two different patterns of pressure generation. The present study further analyzed the influence of ... | ['Adult', 'Deglutition', 'Deglutition Disorders', 'Electromyography', 'Female', 'Humans', 'Male', 'Pressure', 'Tongue', 'Young Adult'] | 29,170,819 | [['M01.060.116'], ['G10.261.178'], ['C06.405.117.119', 'C09.775.174'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.715'], ['A03.556.500.885', 'A14.549.885'], ['M01.060.116.815']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Small RNA sequencing revealed aberrant piRNA expression profiles in colorectal cancer. | Piwi‑interacting RNAs (piRNAs), a novel class of non‑coding RNAs, are enriched in germ cells and implicated in spermatogenesis. Emerging evidence demonstrated deregulated expression of piRNAs in numerous tumor types. However, changes in piRNA expression profiles in colorectal cancer (CRC) have not yet been investigated... | ['Aged', 'Colorectal Neoplasms', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Prognosis', 'RNA, Small Interfering', 'Sequence Analysis, RNA'] | 31,115,555 | [['M01.060.116.100'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E01.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Carboxyl residues in the iron-sulfur protein are involved in the proton pumping activity of P. denitrificans bc(1) complex. | A study is presented on chemical modification of the three subunit Paracoccus denitrificans bc(1) complex. N-(Ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline (EEDQ) treatment caused a loss of the proton pumping activity of liposome-reconstituted bc(1) complex. A similar effect, which is referred to as the decoupling effe... | ['Amino Acid Sequence', 'Dicyclohexylcarbodiimide', 'Electron Transport Complex III', 'Iron-Sulfur Proteins', 'Liposomes', 'Macromolecular Substances', 'Molecular Sequence Data', 'Paracoccus denitrificans', 'Proton Pumps', 'Quinolines', 'Sequence Homology, Amino Acid'] | 11,735,423 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D02.491.203.385'], ['D05.500.562.750.500', 'D08.811.600.250.875.500', 'D08.811.682.830.500', 'D12.776.157.427.374.375.954', 'D12.776.157.530.450.250.875.303', 'D12.776.543.277.875.500', 'D12.776.543.585.450.250.875.468', 'D12.776.556.579.374.375.142'], ['D12.776.157.427.37... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Factors associated with early opioid prescription among workers with low back injuries. | UNLABELLED: Prescription of opioids for nonmalignant musculoskeletal pain has increased substantially in recent years, but there is little information on the incidence of, or factors associated with, such prescription for work-related back pain. In a prospective cohort study (N = 1,067), we examined associations betwee... | ['Adult', 'Analgesics, Opioid', 'Body Mass Index', 'Cohort Studies', 'Comorbidity', 'Disability Evaluation', 'Disease Progression', 'European Continental Ancestry Group', 'Female', 'Hispanic Americans', 'Humans', 'Interviews as Topic', 'Logistic Models', 'Low Back Pain', 'Male', 'Middle Aged', 'Occupational Diseases', ... | 17,018,332 | [['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Structure and temporal dynamics of the bacterial communities associated to microhabitats of the coral Oculina patagonica. | Corals are known to contain a diverse microbiota that plays a paramount role in the physiology and health of holobiont. However, few studies have addressed the variability of bacterial communities within the coral host. In this study, bacterial community composition from the mucus, tissue and skeleton of the scleractin... | ['Animals', 'Anthozoa', 'Denaturing Gradient Gel Electrophoresis', 'Ecosystem', 'Mediterranean Sea', 'Vibrio'] | 27,690,185 | [['B01.050'], ['B01.050.500.308.237'], ['E05.196.401.402.117', 'E05.301.300.319.201'], ['G16.500.275.157', 'N06.230.124'], ['Z01.756.592'], ['B03.440.450.900.859', 'B03.660.250.830.830']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Relationships between soil nutrient contents and soil enzyme activities in Pinus massoniana stands with different ages in Three Gorges Reservoir Area]. | Based on the measurements of soil nutrient contents and enzyme activities and the canonical correspondence analysis (CCA), this paper studied the relationships between soil nutrient contents and soil enzyme activities in different age Pinus massoniana stands in Three Gorges Reservoir Area. Among the test stands, mature... | ['Cellulase', 'China', 'Nitrogen', 'Peroxidase', 'Phosphorus', 'Pinus', 'Rivers', 'Soil', 'Time Factors', 'Water Supply', 'beta-Fructofuranosidase'] | 22,586,971 | [['D08.811.277.450.420.200.200'], ['Z01.252.474.164'], ['D01.268.604', 'D01.362.625'], ['D08.811.682.732.700'], ['D01.268.666'], ['B01.650.940.800.575.912.625.875.777'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G01.910.857'], ['J01.293.82... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Standards for reference services in health sciences libraries: the reference product. | Standards for reference services were prepared by a committee of the Oregon Health Sciences Libraries Association (OHSLA). The standards are qualitative and address the following: quality control, appropriateness, accuracy, documentation, timeliness, accessibility, confidentiality, and evaluation. The standards are com... | ['Information Services', 'Libraries, Medical', 'Oregon'] | 10,278,689 | [['L01.453'], ['J03.400.596.831.937', 'L01.346.596.719.875'], ['Z01.107.567.875.560.550', 'Z01.107.567.875.580.550']] | ['Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
A calorimetric study of 3d metal ions-acyclovir interactions. The 2-hydroxyethoxymethyl group of acyclovir mimics the role of ribose in deoxy-guanosine and guanosine promoting the coordination through N(7). | The equilibrium constants and enthalpic values of metal acyclovir complexes have been determined by calorimetry for Co(II) (log K=0.96+/-0.05, DeltaH (kJ/mol)=-19.7+/-1.3), Ni(II) (log K=1.39+/-0.03, DeltaH (kJ/mol)=-21.5+/-1.0), Cu(II) (log K=1.83+/-0.03, DeltaH (kJ/mol)=-23.2+/-0.8) and Zn(II) (log K=0.71+/-0.06, Del... | ['Acyclovir', 'Antiviral Agents', 'Binding Sites', 'Calorimetry', 'Deoxyguanosine', 'Guanosine', 'In Vitro Techniques', 'Macromolecular Substances', 'Metals', 'Ribose', 'Thermodynamics'] | 11,583,785 | [['D03.633.100.759.758.399.454.250'], ['D27.505.954.122.388'], ['G02.111.570.120'], ['E05.196.131'], ['D03.633.100.759.590.454.240', 'D13.570.230.360', 'D13.570.583.454.240'], ['D03.633.100.759.590.454', 'D13.570.583.454', 'D13.570.800.453'], ['E05.481'], ['D05'], ['D01.552'], ['D09.947.875.627.651'], ['G01.906']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Haplotype estimation using sequencing reads. | High-throughput sequencing technologies produce short sequence reads that can contain phase information if they span two or more heterozygote genotypes. This information is not routinely used by current methods that infer haplotypes from genotype data. We have extended the SHAPEIT2 method to use phase-informative seque... | ['Child', 'Fathers', 'Female', 'Genome, Human', 'Genotype', 'Haplotypes', 'Humans', 'Male', 'Models, Genetic', 'Mothers', 'Polymorphism, Single Nucleotide', 'Sequence Analysis, DNA'] | 24,094,745 | [['M01.060.406'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['G05.360.340.350'], ['G05.380'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.397'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['G05.365.795.598'], ['E05.393.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Microspectrophotometric quantitation of nucleic acid and protein in irradiated epidermis. | Nucleic acid and proteins of newborn rat tail subjected to local X-irradiation were microspectrophotometrically studied. Feulgen, gallocyanine chrom-alum and naphthol yellow S methods were performed for demonstration of DNA, total nucleic acid and proteins respectively. The amount of proteins and total nucleic acid inc... | ['Animals', 'DNA', 'Nucleic Acids', 'Proteins', 'Rats', 'Skin', 'Spectrophotometry', 'Tail', 'Time Factors'] | 1,258,094 | [['B01.050'], ['D13.444.308'], ['D13.444'], ['D12.776'], ['B01.050.150.900.649.313.992.635.505.700'], ['A17.815'], ['E05.196.712.726', 'E05.196.867.826'], ['A13.895'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lipoprotein lipase facilitates very low density lipoprotein binding to the subendothelial cell matrix. | The effect of bovine lipoprotein lipase (LPL) on very low density lipoprotein (VLDL) binding to subendothelial matrix was studied. Without LPL, VLDL bound poorly to the matrix. However, decreasing NaCl or elevating Ca++ concentration increased matrix VLDL binding. With LPL, VLDL binding was markedly increased. Since LP... | ['Animals', 'Aorta', 'Cattle', 'Cells, Cultured', 'Endothelium, Vascular', 'Female', 'Humans', 'Kinetics', 'Lipoprotein Lipase', 'Lipoproteins, VLDL', 'Milk', 'Protein Binding', 'Swine'] | 8,343,159 | [['B01.050'], ['A07.015.114.056'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.352.100.430'], ['D10.532.599', 'D12.776.521.622'], ['A12.200.455', 'A12.790', 'G07.203.100.700',... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A Distinct Endocytic Mechanism of Functionalized-Silica Nanoparticles in Breast Cancer Stem Cells. | Nanoparticles provide new fields for life medical science application, including targeted-drug delivery and cancer treatment. To maximize the delivery efficiency of nanoparticle, one must understand the uptake mechanism of nanoparticle in cells, which may determine their ultimate fate and localization in cells. Recentl... | ['Breast Neoplasms', 'Endocytosis', 'Female', 'Humans', 'MCF-7 Cells', 'Nanoparticles', 'Neoplastic Stem Cells', 'Silicon Dioxide'] | 29,176,652 | [['C04.588.180', 'C17.800.090.500'], ['G04.417'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.630'], ['J01.637.512.600'], ['A11.872.650'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Predictive Factors of Eribulin Activity in Metastatic Breast Cancer Patients. | OBJECTIVES: Predictive factors of response to eribulin are lacking. We aimed to investigate the activity and safety of eribulin in a real-world population of metastatic breast cancer (MBC) patients and to identify possible predictive factors of progression-free survival (PFS) and objective response.METHODS: We retrospe... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Breast Neoplasms', 'Disease-Free Survival', 'Female', 'Furans', 'Humans', 'Ketones', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Retrospective Studies', 'Treatment Outcome'] | 30,036,884 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['D03.383.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dentin-predentin complex and its permeability: physiologic overview. | The major channels for solute diffusion across dentin are the dentinal tubules. Since dentin permeation is proportional to the product of tubule number and diameter, both of which increase as the tubules converge on the pulp, we find that dentin permeability increases rapidly as the pulp chamber is approached. The pres... | ['Animals', 'Biological Transport', 'Blood Proteins', 'Capillaries', 'Capillary Permeability', 'Dental Cavity Preparation', 'Dental Pulp', 'Dentin', 'Dentin Permeability', 'Dentin Sensitivity', 'Dentin, Secondary', 'Diffusion', 'Exudates and Transudates', 'Fibrinogen', 'Humans', 'Odontoblasts', 'Osmosis', 'Pressure', '... | 3,857,264 | [['B01.050'], ['G03.143'], ['D12.776.124'], ['A07.015.461.165'], ['G03.143.330', 'G09.330.165'], ['E06.931.325'], ['A14.549.167.900.260'], ['A14.549.167.900.280'], ['G10.549.845.461'], ['C07.793.266'], ['A14.549.167.900.280.280', 'C07.793.237.378'], ['G01.202', 'G02.196'], ['A12.383'], ['D12.776.124.050.250', 'D12.776.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Heparan sulfate staining of the glomerular basement membrane in relation to circulating anti-DNA and anti-heparan sulfate reactivity: a longitudinal study in NZB/W F1 mice. | Reactivity of serum antibodies with heparan sulfate (HS) has been associated with human and murine lupus nephritis, although the aetiological significance of this association is not clear. Recent work from our laboratories showed that binding of these antibodies to HS could be mediated by histone containing immune comp... | ['Animals', 'Antibodies, Antinuclear', 'Basement Membrane', 'DNA', 'Female', 'Fluorescent Antibody Technique, Direct', 'Heparitin Sulfate', 'Immunoglobulins', 'Kidney', 'Kidney Glomerulus', 'Longitudinal Studies', 'Lupus Erythematosus, Systemic', 'Mice', 'Mice, Inbred NZB'] | 8,845,053 | [['B01.050'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['A10.272.220', 'A10.615.179'], ['D13.444.308'], ['E01.370.225.500.607.512.240.300', 'E01.370.225.750.551.512.240.300', 'E05.200.500.607.512.240.300', 'E05.200.750.551.512.240.300', 'E05.478.583.375.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Protein cross-migration during isolation of nuclei from mixtures of heated and unheated HeLa cells. | To investigate the cross-migration of proteins during nuclear isolation heated and control cells were mixed prior to nuclear isolation. These nuclei were stained with fluorescein isothiocyanate (FITC, a protein-specific stain) and with propidium iodide (PI, a DNA-specific stain). Flow cytometric (FCM) analysis showed t... | ['Cell Fractionation', 'Cell Nucleus', 'Cell Separation', 'Flow Cytometry', 'HeLa Cells', 'Hot Temperature', 'Humans', 'Neoplasm Proteins', 'Staining and Labeling'] | 6,201,947 | [['E05.242.251'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['A11.251.210.190.40... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Socioeconomic factors may contribute to neoadjuvant chemotherapy use in metastatic epithelial ovarian carcinoma. | OBJECTIVE.: To identify patient characteristics which predict receipt of neoadjuvant chemotherapy (NCT) versus standard therapy (ST) in metastatic ovarian cancer. METHODS.: A retrospective matched case control study was conducted of 52 women treated with NCT compared to 104 women who received standard treatment from 19... | ['Age Factors', 'Case-Control Studies', 'Chemotherapy, Adjuvant', 'Employment', 'Female', 'Humans', 'Insurance, Health', 'Middle Aged', 'Multivariate Analysis', 'Neoadjuvant Therapy', 'Ovarian Neoplasms', 'Retrospective Studies', 'Socioeconomic Factors'] | 19,772,939 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E02.186.170', 'E02.319.170'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Interference from mere thinking: mental rehearsal temporarily disrupts recall of motor memory. | Interference between successively learned tasks is widely investigated to study motor memory. However, how simultaneously learned motor memories interact with each other has been rarely studied despite its prevalence in daily life. Assuming that motor memory shares common neural mechanisms with declarative memory syste... | ['Cues', 'Female', 'Hand', 'Humans', 'Imagination', 'Learning', 'Male', 'Mental Recall', 'Psychological Tests', 'Psychomotor Performance', 'Thinking', 'Visual Perception', 'Young Adult'] | 24,805,082 | [['F02.463.425.234'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.188.634'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.425.540.641'], ['F04.711'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['F02.463.785'], ['F02.463.593.932'], ['M01.060.116.815']] | ['Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis. | Activation of muscle-specific genes by members of the myocyte enhancer factor 2 (MEF2) and MyoD families of transcription factors is coupled to histone acetylation and is inhibited by class II histone deacetylases (HDACs) 4 and 5, which interact with MEF2. The ability of HDAC4 and -5 to inhibit MEF2 is blocked by phosp... | ['14-3-3 Proteins', 'Animals', 'COS Cells', 'Carrier Proteins', 'Cell Differentiation', 'Cell Line', 'Chlorocebus aethiops', 'DNA-Binding Proteins', 'Embryonic and Fetal Development', 'Gene Expression Regulation, Developmental', 'Histone Deacetylases', 'MEF2 Transcription Factors', 'Mice', 'Muscle, Skeletal', 'MyoD Pro... | 11,390,982 | [['D12.644.360.024.050', 'D12.776.157.057.002', 'D12.776.476.024.050'], ['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D12.776.157'], ['G04.152'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D12.776.260'], ['G07.345.500.325', 'G08.686.784.170'], ['G05.308.310'], ['D08.811.277... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Potassium channel activators: comparative structural study of pinacidil, diazoxide and cromakalim]. | A conformational analysis has been performed with SYBYL starting from the energy optimized (Tripos force field) X-ray conformation of (R,S)-pinacidil. The geometry of four selected low energy conformers has been reoptimized using the AM1 semiempirical Molecular Orbital method (MOPAC 5.0), and the total energy of the op... | ['Antihypertensive Agents', 'Benzopyrans', 'Cromakalim', 'Diazoxide', 'Guanidines', 'Molecular Conformation', 'Molecular Structure', 'Pinacidil', 'Potassium Channels', 'Pyrroles'] | 7,503,508 | [['D27.505.954.411.162'], ['D03.383.663.283', 'D03.633.100.150'], ['D03.383.129.578.150', 'D03.383.663.283.455', 'D03.633.100.150.455'], ['D02.886.590.700.135.300', 'D02.886.655.500.300', 'D03.633.100.174.300'], ['D02.078.370'], ['G02.111.570.820'], ['G02.111.570', 'G02.466'], ['D02.078.370.729'], ['D12.776.157.530.400... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical classification of androgenetic baldness and its therapeutic implications]. | In order to understand the various operative indications in baldness surgery, we describe a dynamic classification of baldness with practical implications. The most predictive factors of this classification are scalp laxity and the height of the crown. | ['Alopecia', 'Elasticity', 'Hair', 'Humans', 'Male', 'Scalp', 'Surgical Flaps'] | 7,864,575 | [['C17.800.329.937.122', 'C23.300.035'], ['G01.374.590'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.456.810'], ['A10.850.710', 'E07.862.710']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A case of Fahr's disease presenting "diffuse neurofibrillary tangles with calcification"]. | 77-year-old woman presented memory disturbance, hallucination, and personality change since the summer of 1988. Laboratory findings revealed normal serum Ca, P, HS-PTH levels and Ellsworth-Howard test was intact. Neuroradiological studies disclosed calcification in the dentate nucleus, putamen, globus pallidus and thal... | ['Aged', 'Atrophy', 'Basal Ganglia Diseases', 'Brain', 'Calcinosis', 'Female', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging', 'Neurofibrillary Tangles', 'Temporal Lobe', 'Time Factors'] | 12,701,220 | [['M01.060.116.100'], ['C23.300.070'], ['C10.228.140.079'], ['A08.186.211'], ['C18.452.174.130'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.675.609.520', 'A11.284.430.214.190.750.640.520', 'A... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Xanthogranulomatous pyelonephritis in children: analysis by diagnostic modalities. | Xanthogranulomatous pyelonephritis (XGP), an uncommon chronic inflammatory renal disorder of middle-aged women, is rarely seen in childhood. We report the sonographic findings in a 2-year-old girl with the diffuse form of XGP and discuss the role of newer imaging modalities in the diagnosis and management of this disor... | ['Child, Preschool', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Pyelonephritis, Xanthogranulomatous', 'Radionuclide Imaging', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 2,185,588 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C12.777.419.570.643.790.810', 'C12.777.419.570.821.717.810', 'C13.351.968.419.570.643.790.810', 'C13.351.968.419.570.821.717.810'], ['E01.370.350.710', 'E01.370.384.730'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.8... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
One-year double-blind study of the neurocognitive efficacy of olanzapine, risperidone, and haloperidol in schizophrenia. | Neurocognitive deficits in schizophrenia can reach 1 to 2 standard deviations below healthy controls. The comparative effect of typical and atypical antipsychotic medications on neurocognition is controversial, and based primarily on studies with small samples and large doses of typical comparator medications. The pres... | ['Adolescent', 'Adult', 'Antipsychotic Agents', 'Attention', 'Benzodiazepines', 'Double-Blind Method', 'Female', 'Haloperidol', 'Humans', 'Male', 'Middle Aged', 'Olanzapine', 'Reaction Time', 'Risperidone', 'Schizophrenia', 'Treatment Outcome'] | 16,202,565 | [['M01.060.057'], ['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F02.830.104.214'], ['D03.633.100.079.080'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D02.522.352.506'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids. | The inhibitory and stimulatory effects of six flavonoids with distinct hydroxylation patterns on the recombinant and hepatic mouse and human CYP1A P-450s were studied. cDNA-expressed mouse CYP1A1 and CYP1A2 differed in their sensitivity to both hydroxylated and nonhydroxylated flavonoids, respectively. A comparison bet... | ['Animals', 'Cytochrome P-450 CYP1A2', 'Cytochrome P-450 Enzyme Inhibitors', 'Cytochrome P-450 Enzyme System', 'Flavonoids', 'Humans', 'Isoenzymes', 'Mice', 'Microsomes, Liver', 'NADH, NADPH Oxidoreductases', 'Oxidoreductases, N-Demethylating', 'Recombinant Proteins', 'Species Specificity', 'Structure-Activity Relation... | 8,155,716 | [['B01.050'], ['D08.244.453.005.443', 'D08.244.453.100.750', 'D08.811.682.690.708.170.010.443', 'D08.811.682.690.708.170.020.750', 'D12.776.422.220.453.010.443', 'D12.776.422.220.453.100.750'], ['D27.505.389.500', 'D27.505.519.389.335'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D03.383.663.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Localization of sex steroid hormone and sex steroid hormone receptors in human ovarian epithelial tumor]. | In some ovarian tumors, such as endometrioid adenocarcinoma, dysfunctional uterine bleeding occurs, and the endocrinological aspects were studied in the following way: 1) In 3 patients with epithelial ovarian tumor and postmenopausal uterine bleeding, preoperative plasma estradiol (E2) and progesterone (P) concentratio... | ['Adenocarcinoma', 'Carcinoma', 'Cytosol', 'Estradiol', 'Female', 'Humans', 'Immunohistochemistry', 'Ovarian Neoplasms', 'Progesterone', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Testosterone'] | 2,299,246 | [['C04.557.470.200.025'], ['C04.557.470.200'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.51... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A conserved nuclease domain in the archaeal Holliday junction resolving enzyme Hjc. | Holliday junction resolving enzymes are ubiquitous proteins that function in the pathway of homologous recombination, catalyzing the rearrangement and repair of DNA. They are metal ion-dependent endonucleases with strong structural specificity for branched DNA species. Whereas the eukaryotic nuclear enzyme remains unkn... | ['Amino Acid Sequence', 'Archaeal Proteins', 'Catalytic Domain', 'Cloning, Molecular', 'Conserved Sequence', 'Endodeoxyribonucleases', 'Escherichia coli', 'Holliday Junction Resolvases', 'Kinetics', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Nucleic Acid Conformation', 'Oligonucleotides', 'Potassium Perm... | 10,940,317 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.090'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.393.220'], ['G02.111.570.580'], ['D08.811.277.352.335.350', 'D08.811.277.352.355.325'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.277.352.335.350.400', 'D08.811.277.352... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Novel solution for luminal access loss into the double-layered LVIS Blue™ construct. | We described a novel solution for a challenging case of double-layered LVIS Blue™ (LB) stent construct retraction into a large cavernous aneurysm. The double-layered LB stent construct was used as a flow diverter for treatment of a large cavernous aneurysm. Our solution comprised a balloon angioplasty and placement of ... | ['Aged', 'Angioplasty, Balloon', 'Catheters', 'Cerebral Angiography', 'Endovascular Procedures', 'Female', 'Humans', 'Intracranial Aneurysm', 'Stents'] | 28,675,349 | [['M01.060.116.100'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['E07.132'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['E04.100.814.529', 'E04.502.382'], ['B01.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
4-Chlorobenzoyl berbamine, a novel berbamine derivative, induces apoptosis in multiple myeloma cells through the IL-6 signal transduction pathway and increases FOXO3a-Bim expression. | Multiple myeloma (MM) is an incurable hematopoietic malignancy, although many novel therapeutic agents have been explored. In the present study, we showed that 4-chlorobenzoyl berbamine (BBD9), a novel derivative of berbamine, inhibited the growth of 4 MM cell lines (U266, RPMI 8226, MM1.R and MM1.S). After a 24-h trea... | ['Apoptosis', 'Apoptosis Regulatory Proteins', 'Bcl-2-Like Protein 11', 'Benzylisoquinolines', 'Caspase 3', 'Caspase 8', 'Caspase 9', 'Cell Line, Tumor', 'Cell Proliferation', 'Forkhead Box Protein O3', 'Forkhead Transcription Factors', 'G2 Phase Cell Cycle Checkpoints', 'Humans', 'Interleukin-6', 'Membrane Proteins', ... | 23,624,712 | [['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['D12.644.360.075.323', 'D12.776.476.075.323', 'D12.776.543.116', 'D12.776.624.664.700.025'], ['D03.132.098', 'D03.633.100.531.085'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.0... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-dose-rate intracavitary irradiation in the treatment of carcinoma of the uterine cervix: early experience with 84 patients. | Eighty-four patients with previously untreated invasive carcinoma of the uterine cervix were treated by high-dose-rate intracavitary irradiation using a remotely controlled afterloading system (Ralstron) with or without external irradiation at the National Cancer Center Hospital, Tokyo, between 1977 and 1981. Survival ... | ['Adult', 'Aged', 'Brachytherapy', 'Cobalt Radioisotopes', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Middle Aged', 'Radiotherapy Dosage', 'Uterine Cervical Neoplasms'] | 3,360,656 | [['M01.060.116'], ['M01.060.116.100'], ['E02.815.150'], ['D01.268.556.185.500.354', 'D01.268.956.155.500.354', 'D01.496.239.354', 'D01.496.749.256', 'D01.552.544.185.500.354'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.815.639'], ['C04.588.945.418.948.85... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The violent and sexual victimization of college women: is repeat victimization a problem? | Little attention has been given to repeat violent and sexual victimization among college women. Using two national-level data sets, the authors find that a small proportion of college women experience a large proportion of violent and sexual victimizations. Women are more likely to experience repeat sexual victimizatio... | ['Adult', 'Battered Women', 'Crime Victims', 'Female', 'Humans', 'Incidence', 'Rape', 'Self Disclosure', 'Self Efficacy', 'Sexual Partners', 'Surveys and Questionnaires', 'United States'] | 18,309,041 | [['M01.060.116'], ['M01.975.155'], ['M01.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['I01.198.240.748.640', 'I01.198.240.856.744', 'I01.880.735.900.772'], ['F01.752.747.792.662'], ['F01.752.747... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Novel assays of multiple lymphocyte functions in whole blood measure: new mechanisms of action of mycophenolate mofetil in vivo. | The antiproliferative effects of MMF are believed to be the mechanism of its immunosuppressive action. We further investigated the mechanisms of action by assessing the pharmacodynamics (PD) of MMF in treated animals using whole blood assays not only of lymphocyte proliferation but also of activation. In vitro, differe... | ['Animals', 'Dose-Response Relationship, Drug', 'Immunosuppressive Agents', 'Lymphocytes', 'Male', 'Mycophenolic Acid', 'Rats', 'Rats, Inbred Lew', 'Thymidine'] | 12,182,459 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.696.477.656'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['D02.241.081.193.678', 'D10.251.618'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.280', 'B01.050.150.900.649.313.992.635.505.700.400.280'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stereoscopic digital mammogram: Usefulness in daily practice. | OBJECTIVES: To assess the benefit of stereoscopic digital mammography in daily practice.METHODS: Stereoscopic digital (SD) mammography allows a fused 3D view of mammogram. A 4-degree cranio-caudal (CC) angle view matched with a regular CC view allows generating a stereoscopic view. Three breast radiologists reviewed re... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Diseases', 'Breast Neoplasms', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Mammography', 'Middle Aged', 'Young Adult'] | 29,621,618 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C17.800.090'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.700.500'], ['M01.060.116.630'], ['M01.060.116.815']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Initial steps of insulin signaling and glucose transport are defective in the type 2 diabetic rat heart. | OBJECTIVE: Whole body insulin resistance and diabetes are risk factors for cardiovascular diseases, yet little is known about insulin resistance in the diabetic heart. The aim of this work was to define the insulin response in hearts of the Goto-Kakizaki (GK) rat, a polygenic model of spontaneous type 2 diabetes.METHOD... | ['Animals', 'Biological Transport', 'Cell Membrane', 'Diabetes Mellitus, Type 2', 'Glucose', 'Glucose Transporter Type 1', 'Glucose Transporter Type 4', 'Insulin', 'Insulin Receptor Substrate Proteins', 'Male', 'Models, Animal', 'Monosaccharide Transport Proteins', 'Muscle Proteins', 'Myocardium', 'Phosphoproteins', 'P... | 14,736,545 | [['B01.050'], ['G03.143'], ['A11.284.149'], ['C18.452.394.750.149', 'C19.246.300'], ['D09.947.875.359.448'], ['D12.776.157.530.500.500.500', 'D12.776.157.530.937.563.500', 'D12.776.543.585.500.500.500', 'D12.776.543.585.937.625.500'], ['D12.776.157.530.500.500.937', 'D12.776.157.530.937.563.937', 'D12.776.543.585.500.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tacrolimus suppresses tumour necrosis factor-alpha and protects against splanchnic artery occlusion shock. | 1. Tumour necrosis factor (TNF-alpha) is a pleiotropic cytokine which is deeply involved in the pathogenesis of splanchnic artery occlusion (SAO) shock. Tacrolimus, formerly known as FK506, is a macrolide antibiotic, that blocks the transcription of several proinflammatory cytokines including TNF-alpha. 2. Male anaesth... | ['Animals', 'Blood Pressure', 'Constriction, Pathologic', 'Endothelium, Vascular', 'Immunohistochemistry', 'Immunosuppressive Agents', 'Leukocyte Count', 'Macrophages', 'Male', 'Muscle Contraction', 'Muscle, Smooth, Vascular', 'Peroxidase', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Reverse Transcriptase Polyme... | 10,385,251 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.300.287'], ['A07.015.700.500', 'A10.272.491.355'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
A phantom extinction? New insights into extinction dynamics of the Don-hare Lepus tanaiticus. | The Pleistocene to Holocene transition was accompanied by a worldwide extinction event affecting numerous mammalian species. Several species such as the woolly mammoth and the giant deer survived this extinction wave, only to go extinct a few thousand years later during the Holocene. Another example for such a Holocene... | ['Animals', 'DNA, Mitochondrial', 'Extinction, Biological', 'Hares', 'Phylogeny'] | 20,695,962 | [['B01.050'], ['D13.444.308.283.225'], ['G16.510'], ['B01.050.150.900.649.313.968.400'], ['G05.697', 'G16.075.605', 'L01.100.697']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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