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[Influence of various physical factors on the developmental capacities of the ovum of Artemia salina]. | Artemia salina dry eggs exhibit a great resistance to different physical factors: acceleration and vibration, low temperature, high vacuum and magnetic fields. Vibration test, alone or combined with acceleration test decreases the Artemia salina egg developmental capacity. Nevertheless, the differences are small and mu... | ['Acceleration', 'Animals', 'Atmospheric Pressure', 'Crustacea', 'Electromagnetic Fields', 'Electromagnetic Phenomena', 'Female', 'Ovum', 'Temperature', 'Vibration'] | 140,753 | [['G01.482.107'], ['B01.050'], ['G16.500.750.274', 'N06.230.300.100.185'], ['B01.050.500.131.365'], ['G01.358.500.260', 'G01.358.750.500'], ['G01.358.500'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Electron transfer reactions in the alkene mono-oxygenase complex from Nocardia corallina B-276. | Nocardia corallina B-276 possesses a multi-component enzyme, alkene mono-oxygenase (AMO), that catalyses the stereoselective epoxygenation of alkenes. The reductase component of this system has been shown by EPR and fluorescence spectroscopy to contain two prosthetic groups, an FAD centre and a [2Fe-2S] cluster. The ro... | ['Electron Spin Resonance Spectroscopy', 'Electron Transport', 'Flavin-Adenine Dinucleotide', 'Kinetics', 'Nocardia', 'Oxidation-Reduction', 'Oxidoreductases', 'Oxygenases', 'Spectrophotometry, Ultraviolet'] | 10,085,230 | [['E05.196.867.519.274'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D03.633.100.733.315.650.249', 'D03.633.100.759.646.138.506', 'D03.633.300.507.650.249', 'D08.211.474.650.249', 'D13.695.667.138.506', 'D13.695.827.068.506', 'D23.767.405.650.249'], ['G01.374.661', 'G02.111.490'], ['B03.510.024.981.550'], ['G... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Feasibility and effectiveness of a lifestyle intervention after complicated pregnancies to improve risk factors for future cardiometabolic disease. | OBJECTIVES: To evaluate the feasibility and effectiveness of a postpartum lifestyle intervention after pregnancies complicated by preeclampsia, fetal growth restriction (FGR) and/or gestational diabetes mellitus (GDM) to improve maternal risk factors for future cardiometabolic disease.METHODS: Women following a complic... | ['Cardiovascular Diseases', 'Diabetes Mellitus', 'Diabetes, Gestational', 'Feasibility Studies', 'Female', 'Fetal Growth Retardation', 'Healthy Lifestyle', 'Humans', 'Non-Randomized Controlled Trials as Topic', 'Postnatal Care', 'Postpartum Period', 'Pre-Eclampsia', 'Pregnancy', 'Risk Factors'] | 30,825,935 | [['C14'], ['C18.452.394.750', 'C19.246'], ['C13.703.170', 'C18.452.394.750.448', 'C19.246.200'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['F01.829.458.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.25... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
HIV awareness in China among women of reproductive age (1997-2005): a decomposition analysis. | HIV prevalence in China is less than one per cent, but the absolute number of people living with HIV/AIDS is large and growing. Given the limited scope of any potential cure for HIV, prevention plays a crucial role in controlling the epidemic. This paper examines the evolution of HIV awareness among women in China betw... | ['Acquired Immunodeficiency Syndrome', 'Adolescent', 'Adult', 'Awareness', 'China', 'Female', 'HIV Infections', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Middle Aged', 'Prevalence'] | 23,830,139 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.057'], ['M01.060.116'], ['F02.463.188.150'], ['Z01.252.474.164'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.8... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Revision posterior cruciate ligament reconstruction using a modified tibial-inlay double-bundle technique. | BACKGROUND: Revision of an unsuccessful posterior cruciate ligament (PCL) reconstruction is a complicated clinical procedure with an outcome that may be less satisfactory than that after a typical primary PCL reconstruction. The purpose of this study was to evaluate the reasons for failure of primary PCL reconstruction... | ['Achilles Tendon', 'Adult', 'Arthroscopy', 'Female', 'Follow-Up Studies', 'Humans', 'Joint Instability', 'Male', 'Middle Aged', 'Posterior Cruciate Ligament', 'Reconstructive Surgical Procedures', 'Reoperation', 'Transplantation, Homologous', 'Treatment Failure', 'Treatment Outcome', 'Young Adult'] | 22,438,000 | [['A02.880.176'], ['M01.060.116'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['M01.060.116.630'], ['A02.513.514.600', 'A02.835.583.512.600', 'A10.... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tetrodotoxin-resistant Na+ spikes of C fibers have at least two subtypes in the isolated bullfrog sciatic nerve. | The C fiber compound action potentials (C-CAPs) were studied for their properties with the vaseline gap method from the isolated bullfrog sciatic nerve. Two components (the fast and the slow C-CAPs) were found to be Na+ dependent and tetrodotoxin-resistant. The conduction velocities of the fast and the slow C-CAPs were... | ['Action Potentials', 'Anesthetics, Local', 'Animals', 'Cadmium', 'Capsaicin', 'Electric Stimulation', 'Electrophysiology', 'Lidocaine', 'Nerve Fibers', 'Rana catesbeiana', 'Sciatic Nerve', 'Sodium', 'Tetrodotoxin'] | 9,014,168 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['B01.050'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.166.099', 'D03.132.760.200', 'D10... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Modeling and design of a cone-beam CT head scanner using task-based imaging performance optimization. | Detection of acute intracranial hemorrhage (ICH) is important for diagnosis and treatment of traumatic brain injury, stroke, postoperative bleeding, and other head and neck injuries. This paper details the design and development of a cone-beam CT (CBCT) system developed specifically for the detection of low-contrast IC... | ['Algorithms', 'Artifacts', 'Cone-Beam Computed Tomography', 'Fluoroscopy', 'Head', 'Humans', 'Image Processing, Computer-Assisted', 'Models, Theoretical', 'Phantoms, Imaging', 'Tomography Scanners, X-Ray Computed', 'X-Rays'] | 27,025,783 | [['G17.035', 'L01.224.050'], ['E05.047'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['E01.370.350.700.225'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.599'], ['E07.671'], ['E07.913'], ['G01.358.500.505.970', 'G01.750.250.970', 'G01.750.750.918']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Imaging faces of shadowed magnetite (Fe(3)O(4)) crystals from magnetotactic bacteria with energy-filtering transmission electron microscopy. | We used energy-filtering transmission electron microscopy to image magnetite crystals isolated from uncultured magnetotactic bacteria. These magnetite crystals were shadowed in high vacuum with platinum at 45 degrees. The shadowed crystals were observed in a Zeiss (Thornwood, NY) CEM902 transmission electron microscope... | ['Bacteria', 'Crystallization', 'Ferrosoferric Oxide', 'Iron', 'Microscopy, Electron, Scanning', 'Oxides'] | 10,469,468 | [['B03'], ['E05.196.300', 'G02.171'], ['D01.490.100.375', 'D01.490.200.350', 'D01.578.285'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D01.248.497.158.685', 'D01.650.550']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
5-HT6 receptors positively coupled to adenylyl cyclase in striatal neurones in culture. | 5-HT receptor positively coupled to adenylyl cyclase in striatal neurones in culture does not correspond to the 5-HT4 receptor. 5-HT induces an increase in cAMP level with an EC50 of 125 nM. 5-HT agonists displayed the following rank order of potencies 5-HT > LSD > 5-MeOT > 5-CT. 8-OH-DPAT, RU 24969 and cisapride were ... | ['Adenylyl Cyclases', 'Animals', 'Antipsychotic Agents', 'Cells, Cultured', 'Corpus Striatum', 'Cyclic AMP', 'Lysergic Acid Diethylamide', 'Methiothepin', 'Mice', 'Neurons', 'Receptors, Serotonin', 'Serotonin Antagonists', 'Serotonin Receptor Agonists'] | 7,696,602 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['A11.251'], ['A08.186.211.200.885.287.249.487'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Geopolymeric adsorbents from fly ash for dye removal from aqueous solution. | Adsorbents from coal fly ash treated by a solid-state fusion method using NaOH were prepared. It was found that amorphous aluminosilicate geopolymers would be formed. These fly ash-derived inorganic polymers were assessed as potential adsorbents for removal of some basic dyes, methylene blue and crystal violet, from aq... | ['Adsorption', 'Carbon', 'Coal Ash', 'Coloring Agents', 'Environmental Restoration and Remediation', 'Particulate Matter', 'Polymers', 'Solutions', 'Water', 'Water Pollution'] | 16,626,729 | [['G01.030', 'G02.020'], ['D01.268.150'], ['D20.633.110'], ['D27.720.233'], ['N06.230.080.600', 'N06.850.460.375'], ['D20.633'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D26.776'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'], ['N06.850.460.790']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of age and photoperiod on the responsiveness of the pituitary gland of the vole (Microtus agrestis) to stimulation by GnRH. | Male voles were raised from birth to 100 days of age in photoperiods of 16L:8D or 6L:18D. In the long photoperiod testes increased in size between 15 and 80 days of age, and there was an increase in seminal vesicle weight from 60 days of age. Spermatozoa were present in the testes at 60 days of age. In the short photop... | ['Animals', 'Arvicolinae', 'Follicle Stimulating Hormone', 'Hypothalamus', 'In Vitro Techniques', 'Light', 'Luteinizing Hormone', 'Male', 'Organ Size', 'Pituitary Gland', 'Pituitary Hormone-Releasing Hormones', 'Seminal Vesicles', 'Sexual Maturation', 'Stimulation, Chemical', 'Testis'] | 3,080,597 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['E05.481'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D06.472.699.322.576.463', 'D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Depressive disorder, coronary heart disease, and stroke: dose-response and reverse causation effects in the Whitehall II cohort study. | BACKGROUND: Systematic reviews examining associations of depressive disorder with coronary heart disease and stroke produce mixed results. Failure to consider reverse causation and dose-response patterns may have caused inconsistencies in evidence.DESIGN: This prospective cohort study on depressive disorder, coronary h... | ['Adult', 'Aged', 'Cause of Death', 'Coronary Disease', 'Depressive Disorder', 'Female', 'Health Surveys', 'Humans', 'Incidence', 'London', 'Male', 'Middle Aged', 'Models, Statistical', 'Prevalence', 'Prognosis', 'Prospective Studies', 'Risk Assessment', 'Risk Factors', 'Stroke', 'Surveys and Questionnaires', 'Time Fac... | 24,491,401 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['C14.280.647.250', 'C14.907.585.250'], ['F03.600.300'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Preemptive therapy for systemic and pulmonary human cytomegalovirus infection in lung transplant recipients. | The incidence and treatment of both systemic and pulmonary human cytomegalovirus (HCMV) infection as well as HCMV-specific T-cell immune responses were investigated in 57 consecutive lung transplant recipients (LTR) by using as cutoffs for preemptive therapy: 300 000 DNA copies/mL whole blood for systemic infections an... | ['Adolescent', 'Adrenal Cortex Hormones', 'Adult', 'Aged', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'Female', 'Heart-Lung Transplantation', 'Humans', 'Immunosuppression', 'Lung Diseases', 'Lung Transplantation', 'Male', 'Middle Aged', 'Pneumonia, Viral... | 19,422,339 | [['M01.060.057'], ['D06.472.040'], ['M01.060.116'], ['M01.060.116.100'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['B04.280.382.150.150'], ['C01.925.256.466.245'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Readiness redefined: a behavioral task during screening predicted 1-year weight loss in the look AHEAD study. | OBJECTIVE: Predicting outcome in weight loss trials from baseline characteristics has proved difficult. Readiness to change is typically measured by self-report.METHODS: Performance of a behavioral task, completion of food records, from the screening period in the Look AHEAD study (n = 549 at four clinical centers) was... | ['Aged', 'Decision Support Techniques', 'Diet Records', 'Exercise', 'Female', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Multivariate Analysis', 'Obesity', 'Patient Participation', 'Randomized Controlled Trials as Topic', 'Self Report', 'Treatment Outcome', 'Weight Loss', 'Weight Reduction Programs'] | 24,151,217 | [['M01.060.116.100'], ['E05.245', 'L01.313.500.750.190'], ['N04.452.859.360'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['M01.06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Impact of experience when using the Rapid Upper Limb Assessment to assess postural risk in children using information and communication technologies. | The Rapid Upper Limb Assessment (RULA) is an observation-based screening tool that has been used to assess postural risks of children in school settings. Studies using eye-tracking technology suggest that visual search strategies are influenced by experience in the task performed. This study investigated if experience ... | ['Adolescent', 'Arm', 'Child', 'Computers, Handheld', 'Eye Movement Measurements', 'Fixation, Ocular', 'Hand', 'Head', 'Humans', 'Microcomputers', 'Observer Variation', 'Occupational Therapy', 'Posture', 'Professional Competence', 'Risk Assessment', 'Video Recording', 'Wrist'] | 23,735,750 | [['M01.060.057'], ['A01.378.800.075'], ['M01.060.406'], ['L01.224.230.260.550.500'], ['E01.370.380.230', 'E01.370.405.245.787'], ['G14.350.253'], ['A01.378.800.667'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.260.550'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850... | ['Named Groups [M]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
A dietary pattern protective against type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)--Potsdam Study cohort. | AIMS/HYPOTHESIS: The aim of this study was to identify a dietary pattern associated with diabetes-related biomarkers and to investigate whether this pattern is associated with the incidence of type 2 diabetes.METHODS: A nested case-control study of 192 cases of incident type 2 diabetes and 382 control subjects matched ... | ['Adiponectin', 'Body Mass Index', 'C-Reactive Protein', 'Case-Control Studies', 'Diabetes Mellitus, Type 2', 'Diet', 'Educational Status', 'Energy Intake', 'Feeding Behavior', 'Female', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Leisure Activities', 'Male', 'Middle Aged', 'Reference Values', 'Smoking'... | 15,889,235 | [['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.500', 'N05.715.360.330.500.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Comparison of diagnostic value between DR and MSCT in fracture and dislocation of foot and ankle]. | OBJECTIVE: To compare the diagnostic value between digital photography (DR) and multi-slice spiral CT (MSCT) in fracture and dislocation of foot and ankle.METHODS: From August 2010 to August 2012, the DR and MSCT data of 52 patients with fracture and dislocation of foot and ankle were compared according to results of s... | ['Adolescent', 'Adult', 'Ankle Injuries', 'Female', 'Foot Injuries', 'Fractures, Bone', 'Humans', 'Image Processing, Computer-Assisted', 'Joint Dislocations', 'Male', 'Middle Aged', 'Multidetector Computed Tomography', 'Photography'] | 24,134,022 | [['M01.060.057'], ['M01.060.116'], ['C26.558.100'], ['C26.558.300'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['C05.550.518', 'C26.289'], ['M01.060.116.630'], ['E01.370.350.350.810.800.500', 'E01.370.350.600.350.700.810.800.500', 'E01.370.350.700.700.810.800.500', 'E01.370.350.700.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Time course of myocardial bloodflow changes during healing of myocardial infarct in pigs. | OBJECTIVE: To define the time course of changes in bloodflow and microsphere content at intervals between one and 28 days after surgical ligation of the circumflex coronary artery.SUBJECTS AND METHODS: After the ligation, pigs were assigned to six groups; all pigs in a group were reanesthetized at either one, three, se... | ['Animals', 'Body Water', 'Cardiomegaly', 'Coronary Circulation', 'Disease Models, Animal', 'Female', 'Male', 'Microspheres', 'Myocardial Infarction', 'Myocardium', 'Swine', 'Time Factors'] | 1,422,997 | [['B01.050'], ['A12.207.200'], ['C14.280.195', 'C23.300.775.250'], ['G09.330.100.324'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E07.565'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['B01.050.150.900.649.313.500.880']... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High level functions for the intuitive use of an assistive robot. | This document presents the research project ARMEN (Assistive Robotics to Maintain Elderly People in a Natural environment), aimed at the development of a user friendly robot with advanced functions for assistance to elderly or disabled persons at home. Focus is given to the robot SAM (Smart Autonomous Majordomo) and it... | ['Aged', 'Aged, 80 and over', 'Disabled Persons', 'Equipment Design', 'Humans', 'Robotics', 'User-Computer Interface', 'Validation Studies as Topic'] | 24,187,193 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.150'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['L01.224.900.910'], ['E05.337.925', 'N05.715.360.335.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
Analgesia following femoral neck surgery. Lateral cutaneous nerve block as an alternative to narcotics in the elderly. | In a prospective controlled randomised trial on patients undergoing operative repair of fractured neck of femur via a lateral incision, the postoperative analgesic requirements of one group of patients who received a lateral cutaneous nerve block were compared with a second group who received no block. The former group... | ['Aged', 'Clinical Trials as Topic', 'Female', 'Femoral Neck Fractures', 'Fracture Fixation, Internal', 'Humans', 'Male', 'Meperidine', 'Nerve Block', 'Pain, Postoperative', 'Prospective Studies', 'Skin', 'Thigh', 'Time Factors'] | 3,896,019 | [['M01.060.116.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C26.404.061.425.500', 'C26.531.750.500', 'C26.558.276.425.500'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.066.399.450', 'D03.383.621.349.450'], ['E03.155.086.711', 'E04.525.210.550']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Health technology assessment: what is it? Current status and perspectives in the field of electrophysiology. | Health technology assessment (HTA) is the multidisciplinary field of policy analysis that studies medical, social, ethical, and economic implications of the development, diffusion, and use of health technologies. Its worldwide diffusion needs to be understood in the context of evidence-based healthcare delivery policy,... | ['Biomedical Technology', 'Electrophysiologic Techniques, Cardiac', 'Europe', 'Forecasting', 'Technology Assessment, Biomedical'] | 21,518,750 | [['J01.897.120.050'], ['E01.370.370.380.245', 'E01.370.405.267'], ['Z01.542'], ['I01.320'], ['N03.880', 'N05.715.360.825']] | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Termiglaucescin, a new polyhydroxy triterpene glucoside from Terminalia glaucescens with antioxidant and anti-inflammatory potential. | Termiglaucescin (1), a new triterpene glucoside, has been isolated from the ethyl acetate extract of the root bark of Terminalia glaucescens Planch. ex Benth, together with 11 known compounds, â-D-glucopyranosyl 2á,3â,6â-trihydroxy-23-galloylolean-12-en-28-oate (2), arjunglucoside I (3), sericoside (4), arjungenin (5),... | ['Anti-Inflammatory Agents', 'Antioxidants', 'Biphenyl Compounds', 'Erythrocytes', 'Glucosides', 'Hemolysis', 'Humans', 'Lipoxygenase Inhibitors', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Phytotherapy', 'Picrates', 'Plant Extracts', 'Plants, Medicinal', 'Protein Denaturation', 'Saponins', 'Serum Album... | 27,997,356 | [['D27.505.954.158'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.559.389.185'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D09.408.348'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.389.480'], ['E05.196.867.519'], ['G02.111.5... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Single-layer closure for typhoid perforations of the small intestine: case report. | The case of a 13-year old girl who presented with generalised peritonitis, septic shock and laboratory features of perforated typhoid enteritis is presented. At laparotomy 25 perforations involving the distal jejunum and the entire ileum were noted with extensive peritoneal soilage. The perforations were successfully c... | ['Adolescent', 'Female', 'Humans', 'Ileal Diseases', 'Intestinal Perforation', 'Jejunal Diseases', 'Polyglactin 910', 'Suture Techniques', 'Typhoid Fever'] | 9,803,640 | [['M01.060.057'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.420'], ['C06.405.469.557'], ['C06.405.469.600'], ['D05.750.728.772', 'D25.720.728.772', 'J01.637.051.720.728.772'], ['E04.987.775'], ['C01.150.252.400.310.821.873']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Comparison of the effects of exercise with chondroitin sulfate on knee osteoarthritis in rabbits. | BACKGROUND: The aim of the study is to compare the effects of exercise therapy with chondroitin sulfate (CS) therapy in an experimental model of osteoarthritis (OA).METHODS: Twenty-one New Zealand rabbits were randomly divided into four groups: normal group (N group, n = 3); OA control group (C group, n = 6); OA plus m... | ['Animals', 'Arthritis, Experimental', 'Cartilage, Articular', 'Chondroitin Sulfates', 'Gene Expression Regulation', 'Microscopy, Electron, Scanning', 'Osteoarthritis, Knee', 'Physical Conditioning, Animal', 'Rabbits', 'Radiography'] | 29,357,891 | [['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['A02.165.407.150', 'A02.835.583.192'], ['D09.698.373.200.300'], ['G05.308'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['C05.550.114.606.500', 'C05.799.613.500'], ['G11.427.410.698.277.280'], ['B01.050.150.900.649.313.968.700'], ['E01.370.350.700']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression and characterization of RNA-dependent RNA polymerase of Dendrolimus punctatus tetravirus. | Dendrolimus punctatus tetravirus (DpTV) has been identified as a new member of the genus Omegatetravirus of the family Tetraviridae that may be related serologically to Nudaurelia capensis virus (NomegaV). To establish the function of DpTV RNA genome and to better understand the mechanism of viral replication, the puta... | ['Amino Acid Sequence', 'Base Sequence', 'Blotting, Northern', 'Blotting, Western', 'DNA, Complementary', 'Genome, Viral', 'Insect Viruses', 'Molecular Sequence Data', 'Mutation', 'RNA Viruses', 'RNA, Viral', 'RNA-Dependent RNA Polymerase', 'Recombinant Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Seq... | 17,002,878 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Noise assessment in intensive care units. | UNLABELLED: Intensive Care Units are environments with numerous noise sources. In different hospital environments it is recommended to have a sound pressure level between 35 and 45db(A).AIM: To measure the sound pressure levels in three ICU at a hospital in Jundia?, State of S?o Paulo, Brazil.STUDY DESIGN: Observationa... | ['Brazil', 'Health Facility Environment', 'Humans', 'Intensive Care Units', 'Noise', 'Reference Standards'] | 20,209,285 | [['Z01.107.757.176'], ['N02.278.220', 'N05.300.430.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['E05.978.808']] | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The Blood Clearance Kinetics and Pathway of Polymeric Micelles in Cancer Drug Delivery. | Polymer micelles are one of the most investigated nanocarriers for drug delivery; many have entered clinical trials and some are in clinic use, but their delivery systems have not yet shown the expected high therapeutic efficacy in clinics. Further understanding their in vivo behaviors, particularly how quickly and by ... | ['Animals', 'Antineoplastic Agents', 'Drug Delivery Systems', 'Female', 'Fluorescence Resonance Energy Transfer', 'Hep G2 Cells', 'Humans', 'Kinetics', 'Lactones', 'Mice', 'Mice, Inbred ICR', 'Micelles', 'Neoplasms', 'Polyethylene Glycols', 'Tumor Cells, Cultured'] | 29,847,730 | [['B01.050'], ['D27.505.954.248'], ['E02.319.300'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D02.540'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Interobserver Variation among Pathologists and Refinement of Criteria in Distinguishing Separate Primary Tumors from Intrapulmonary Metastases in Lung. | Multiple tumor nodules are seen with increasing frequency in clinical practice. On the basis of the 2015 WHO classification of lung tumors, we assessed the reproducibility of the comprehensive histologic assessment to distinguish second primary lung cancers (SPLCs) from intrapulmonary metastases (IPMs), looking for the... | ['Female', 'Humans', 'Lung Neoplasms', 'Male', 'Neoplasm Metastasis', 'Observer Variation', 'Pathologists'] | 29,127,023 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.650', 'C23.550.727.650'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['M01.526.485.810.746', 'N02.360.810.746']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Validity of women's self-reports of cancer screening test utilization in a managed care population. | This study was undertaken to examine the validity of self-reported data on breast and cervical cancer screening behavior. An abbreviated version of the Behavioral Risk Factor Surveillance System telephone survey, including questions on mammography, clinical breast examination (CBE), and Papanicolaou test utilization, w... | ['Adult', 'Aged', 'Breast Neoplasms', 'Female', 'Health Surveys', 'Humans', 'Mammography', 'Managed Care Programs', 'Mass Screening', 'Middle Aged', 'Patient Compliance', 'Physical Examination', 'Practice Guidelines as Topic', 'Reproducibility of Results', 'Risk Factors', 'Truth Disclosure', 'Uterine Cervical Neoplasms... | 14,652,278 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['E01.370.500', 'E05.318.308.980.438.580', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
DNA binding, photo-induced DNA cleavage and cytotoxicity studies of lomefloxacin and its transition metal complexes. | This work was focused on a study of the DNA binding and cleavage properties of lomefloxacin (LMF) and its ternary transition metal complexes with glycine. The nature of the binding interactions between compounds and calf thymus DNA (CT-DNA) was studied by electronic absorption spectra, fluorescence spectra and thermal ... | ['Animals', 'Anti-Infective Agents', 'Antineoplastic Agents', 'Bacteria', 'Cattle', 'Cell Death', 'Cell Line, Tumor', 'Coordination Complexes', 'DNA', 'DNA Cleavage', 'Electrons', 'Electrophoresis, Agar Gel', 'Ethidium', 'Fluoroquinolones', 'Fungi', 'Humans', 'Light', 'Microbial Sensitivity Tests', 'Nucleic Acid Denatu... | 25,541,395 | [['B01.050'], ['D27.505.954.122'], ['D27.505.954.248'], ['B03'], ['B01.050.150.900.649.313.500.380.271'], ['G04.146'], ['A11.251.210.190', 'A11.251.860.180'], ['D01.234', 'D02.257'], ['D13.444.308'], ['G02.111.210', 'G05.193'], ['G01.249.335', 'G01.358.500.750'], ['E05.196.401.153', 'E05.301.300.100'], ['D03.633.300.63... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genotypic diversity and cariogenicity of Candida albicans from children with early childhood caries and caries-free children. | BACKGROUND: The genotypic diversity and cariogenicity of C. albicans from the dental plaque of children are poorly understood. This study aimed to explore the genotypic diversity and cariogenicity of C. albicans from children with early childhood caries and caries-free children.METHODS: Dental plaque samples from 238 c... | ['Candida albicans', 'Case-Control Studies', 'Child, Preschool', 'DNA, Bacterial', 'Dental Caries', 'Genotype', 'Humans'] | 26,576,955 | [['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406.448'], ['D13.444.308.212'], ['C07.793.720.210'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expression of CD45RB functionally distinguishes intestinal T lymphocytes in inflammatory bowel disease. | The importance of CD45RB expression on T cells was already shown in mice where CD45RB(high) expression determines pathogenic potential. In this study, we analyzed the expression of CD45RA, CD45RB, and CD45RO on CD4(+) T lymphocytes in the intestinal mucosa and in the circulation of patients with inflammatory bowel dise... | ['Adult', 'Aged', 'CD4-Positive T-Lymphocytes', 'Case-Control Studies', 'Colitis, Ulcerative', 'Crohn Disease', 'Female', 'Gene Expression Regulation', 'Humans', 'Interleukin-10', 'Interleukin-4', 'Intestinal Mucosa', 'Leukocyte Common Antigens', 'Male', 'Microscopy, Confocal', 'Middle Aged', 'Tumor Necrosis Factor-alp... | 15,020,649 | [['M01.060.116'], ['M01.060.116.100'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['C06... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Coordination numbers of hydrated divalent transition metal ions investigated with IRPD spectroscopy. | Hydration of the divalent transition metal ions, Mn, Fe, Co, Ni, Cu, and Zn, with 5-8 water molecules attached was investigated using infrared photodissociation spectroscopy and photodissociation kinetics. At 215 K, spectral intensities in both the bonded-OH and free-OH stretch regions indicate that the average coordin... | ['Ions', 'Kinetics', 'Photochemical Processes', 'Spectrophotometry, Infrared', 'Transition Elements', 'Water'] | 22,098,330 | [['D01.248.497'], ['G01.374.661', 'G02.111.490'], ['G02.740'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['D01.268.956'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Temporal Trends in Overweight and Obesity, Physical Activity and Screen Time among Czech Adolescents from 2002 to 2014: A National Health Behaviour in School-Aged Children Study. | This study examines trends in overweight and obesity, physical activity (PA) and screen time (ST) among Czech adolescents over a recent 12-year study period. Nationally representative samples consisted of 19,940 adolescents (9760 boys and 10,180 girls) aged 10.5-16.5 years from the Czech Health Behaviour in School-aged... | ['Adolescent', 'Child', 'Computers', 'Czech Republic', 'Exercise', 'Female', 'Humans', 'Logistic Models', 'Male', 'Obesity', 'Overweight', 'Prevalence', 'Time Factors'] | 26,393,638 | [['M01.060.057'], ['M01.060.406'], ['L01.224.230.260'], ['Z01.542.248.395'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.71... | ['Named Groups [M]', 'Information Science [L]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
The effects of BMY-14802 against L-DOPA- and dopamine agonist-induced dyskinesia in the hemiparkinsonian rat. | RATIONALE: L-DOPA continues to be the primary treatment for patients with Parkinson's disease; however, the benefits of long-term treatment are often accompanied by debilitating side effects known as dyskinesias. In recent years, several 5-HT1A receptor agonists have been found to reduce dyskinesia in clinical and expe... | ['Animals', 'Antiparkinson Agents', 'Disease Models, Animal', 'Dopamine Agonists', 'Dyskinesia, Drug-Induced', 'Levodopa', 'Male', 'Motor Activity', 'Parkinson Disease', 'Pyrimidines', 'Rats', 'Rats, Sprague-Dawley', 'Receptor, Serotonin, 5-HT1A', 'Receptors, Dopamine D1'] | 23,389,756 | [['B01.050'], ['D27.505.954.427.090.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.505.519.625.150.151', 'D27.505.696.577.150.151'], ['C10.228.662.262.500', 'C10.597.350.275', 'C10.720.312', 'C23.888.592.350.275', 'C25.100.750', 'C25.723.705.200'], ['D02.092.311.200.480', 'D02.455.426.559.389.657.166.175.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum zinc concentrations in Finns. | Serum zinc concentrations were measured in 1416 Finns aged 15 years and above and belonging to 18 population groups living in various parts of the country. The mean serum zinc concentration was for men 12.7 mumol/l (82 microgram/100 ml) and for women 11.7 mumol/l (77 microgram/100 ml). Zinc levels varied with sex, age,... | ['Adult', 'Age Factors', 'Circadian Rhythm', 'Coronary Disease', 'Fasting', 'Female', 'Finland', 'Glucose Tolerance Test', 'Humans', 'Male', 'Middle Aged', 'Risk', 'Rural Population', 'Seasons', 'Sex Factors', 'Soil', 'Urban Population', 'Zinc'] | 567,420 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['G07.180.562.190'], ['C14.280.647.250', 'C14.907.585.250'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['Z01.542.816.186'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Synergism of theophylline and anticholinergics to inhibit haloperidol-induced catalepsy: a potential treatment for extrapyramidal syndromes. | Extrapyramidal syndromes (EPS) impose a heavy burden on patients receiving antipsychotic therapy. Anticholinergics are the drugs of choice for preventing EPS, but they also produce many adverse reactions. Using the EPS model of haloperidol-induced catalepsy we evaluated the potential therapeutic value of a mixture of l... | ['Animals', 'Basal Ganglia Diseases', 'Catalepsy', 'Cholinergic Antagonists', 'Drug Synergism', 'Drug Therapy, Combination', 'Haloperidol', 'Male', 'Rats', 'Rats, Wistar', 'Syndrome', 'Theophylline', 'Treatment Outcome'] | 20,713,114 | [['B01.050'], ['C10.228.140.079'], ['C10.597.350.200', 'C23.888.592.350.200'], ['D27.505.519.625.120.200', 'D27.505.696.577.120.200'], ['G07.690.773.968.477'], ['E02.319.310'], ['D02.522.352.506'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['C23.550.288.500'], ['D03.1... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of bilateral olfactory bulbectomy on the anterior pituitary corticotropic cell activity in male rats. | Bilateral olfactory bulbectomy (OB) has drastic biochemical and behavioral effects and is often associated with an increase in plasma corticosterone concentrations. This experiment examined the effects of OB on adrenocorticotropin (ACTH) and corticosterone release under basal and stress conditions and on proopiomelanoc... | ['Adrenocorticotropic Hormone', 'Animals', 'Corticosterone', 'Feedback', 'Male', 'Olfactory Bulb', 'Pituitary Gland, Anterior', 'Pro-Opiomelanocortin', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley'] | 10,450,829 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['L01.906.394.211'], ['A08.186.211.200.885.388... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cytotoxic and genotoxic effects of e-liquids and their potential associations with nicotine, menthol and phthalate esters. | In this study, we determined DNA damage and chromosome breakage (indicators of genotoxicity) and cell viability (an indicator of cytotoxicity) in human lymphoblastoid TK6 and Chinese hamster ovary (CHO) cells treated with 33 e-liquids using in vitro single cell gel (comet), micronucleus (MN), and trypan blue assays, re... | ['Animals', 'CHO Cells', 'Cell Survival', 'Cricetinae', 'Cricetulus', 'DNA Damage', 'Dibutyl Phthalate', 'E-Cigarette Vapor', 'Esters', 'Humans', 'Menthol', 'Micronucleus Tests', 'Nicotine', 'Phthalic Acids'] | 32,058,129 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['G04.346'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['G05.200'], ['D02.241.223.805.225'], ['D26.255.165.055.173'], ['D02.241.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.415.510.500.605', 'D02.4... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attenuation-based dual-fluorescent-protein reporter for screening translation inhibitors. | A reporter construct was created on the basis of the transcription attenuator region of the Escherichia coli tryptophan operon. Dual-fluorescent-protein genes for red fluorescent protein and cerulean fluorescent protein were used as a sensor and internal control of gene expression. The sequence of the attenuator was mo... | ['Agar', 'Amino Acid Sequence', 'Anti-Bacterial Agents', 'Culture Media', 'Escherichia coli', 'Fermentation', 'Gene Expression Regulation, Bacterial', 'Genes, Reporter', 'High-Throughput Screening Assays', 'Luminescent Proteins', 'Micromonospora', 'Molecular Sequence Data', 'Operon', 'Peptide Chain Elongation, Translat... | 22,252,829 | [['D09.698.360.041'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D27.505.954.122.085'], ['D27.720.470.305', 'E07.206'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.111.158.249', 'G03.191.249'], ['G05.308.300'], ['G05.360.340.024.340.435'], ['E05.916.680'], ['D12.776.532'], ['B03.300.390.400.500.500... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Telemedicine Practices of Facial Plastic and Reconstructive Surgeons in the United States: The Effect of Novel Coronavirus-19. | Introduction: The objectives of this study among facial plastic and reconstructive surgeons (FPRS), include (1) quantifying the use of telemedicine, (2) examining the impact of novel coronavirus-19 (COVID-19) on telemedicine practices, (3) highlighting the types of telemedicine employed, (4) anticipating how telemedici... | ['Attitude of Health Personnel', 'COVID-19', 'Coronavirus Infections', 'Cross-Sectional Studies', 'Humans', 'Pandemics', 'Perioperative Care', 'Pneumonia, Viral', "Practice Patterns, Physicians'", 'Reconstructive Surgical Procedures', 'Surgeons', 'Surgery, Plastic', 'Surveys and Questionnaires', 'Telemedicine', 'United... | 33,054,375 | [['F01.100.050', 'N05.300.100'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.98... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Extensive integration field beyond the classical receptive field of cat's striate cortical neurons--classification and tuning properties. | Length- and width-summation curves of striate cortex cells revealed that there exist facilitatory, inhibitory or disinhibitory integration fields (IF) beyond the sides and ends of the classical receptive field (RF). The extent of the IFs is most frequently 2-5 times the size of the RFs. The tuning properties of IFs wer... | ['Animals', 'Brain Mapping', 'Cats', 'Evoked Potentials, Visual', 'Motion Perception', 'Neural Inhibition', 'Pattern Recognition, Visual', 'Rotation', 'Space Perception', 'Synaptic Transmission', 'Visual Cortex', 'Visual Fields'] | 7,975,275 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['F02.463.593.932.567'], ['G07.265.755', 'G11.561.616'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['G01.482.703'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Digital imaging and image analysis applied to numerical applications in forensic hair examination. | A method that provides objective data to complement the hair analysts' microscopic observations, which is non-destructive, would be of obvious benefit in the forensic examination of hairs. This paper reports on the use of objective colour measurement and image analysis techniques of auto-montaged images. Brown Caucasia... | ['Female', 'Hair', 'Hair Color', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Microscopy', 'Models, Biological', 'Software'] | 21,334,579 | [['A17.360'], ['G13.500', 'G16.690.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['E05.599.395'], ['L01.224.900']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Immunosuppressive agents in childhood nephrotic syndrome: a meta-analysis of randomized controlled trials. | BACKGROUND: Many children with steroid-sensitive nephrotic syndrome (SSNS) relapse frequently and receive immunosuppressive agents. In this systematic review of randomized controlled trials (RCTs), the benefits and harms of these immunosuppressive agents are evaluated.METHODS: RCTs with outcome data at six months or mo... | ['Adolescent', 'Adrenal Cortex Hormones', 'Child', 'Child, Preschool', 'Chlorambucil', 'Cyclophosphamide', 'Cyclosporine', 'Female', 'Humans', 'Immunosuppressive Agents', 'Infant', 'Levamisole', 'Male', 'Nephrotic Syndrome', 'Randomized Controlled Trials as Topic', 'Recurrence', 'Treatment Outcome'] | 11,318,964 | [['M01.060.057'], ['D06.472.040'], ['M01.060.406'], ['M01.060.406.448'], ['D02.455.526.728.650.156'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['M01.060.703'], ['D02.886.675.346', 'D0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Paternal inheritance of egg traits in mice: a case of genomic imprinting. | Eggs from reciprocal hybrids between the C57BL/6By and BALB/cBy strains were tested for their susceptibility to attack by hyaluronidase and pronase. There were significant reciprocal differences between the F1 females in the responses of their unfertilized eggs to both enzymes. The F1 hybrids from BALB mothers showed t... | ['Animals', 'Crosses, Genetic', 'Fathers', 'Female', 'Genes', 'Hyaluronoglucosaminidase', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Ovum', 'Pedigree', 'Phenotype', 'Pronase'] | 2,620,820 | [['B01.050'], ['E05.393.281'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['G05.360.340.024.340'], ['D08.811.277.450.529', 'D08.811.520.241.700.675'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.05... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Effect of sevoflurane preconditioning on light-induced retinal damage in diabetic rats. | Hyperglycemia and bright light are powerful stress agents that produce an enhanced retinal damage, when simultaneously acting on retina. Previous studies have shown that preconditioning with sevoflurane anesthesia offers a certain degree of protection to retinal cells against light damage. The objective of this study w... | ['Animals', 'Diabetes Mellitus, Experimental', 'Electroretinography', 'Methyl Ethers', 'Platelet Aggregation Inhibitors', 'Random Allocation', 'Rats', 'Rats, Wistar', 'Retina', 'Sevoflurane'] | 29,796,431 | [['B01.050'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['E01.370.380.225', 'E01.370.405.270'], ['D02.355.601'], ['D27.505.954.502.780'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
EphB2 signaling-mediated Sirt3 expression reduces MSC senescence by maintaining mitochondrial ROS homeostasis. | Disruption of mitochondrial reactive oxygen species (mtROS) homeostasis is a key factor inducing UCB-MSC senescence. Accordingly, preventing mtROS accumulation will help in suppressing the UCB-MSC senescence. In this study, we observed that the expressions of EphrinB2 and EphB2 were inversely regulated by UCB-MSC passa... | ['Animals', 'CSK Tyrosine-Protein Kinase', 'Cells, Cultured', 'Cellular Senescence', 'Ephrin-B2', 'Fetal Blood', 'Gene Expression Regulation', 'Humans', 'Male', 'Mesenchymal Stem Cell Transplantation', 'Mesenchymal Stem Cells', 'Mice', 'Mice, Inbred ICR', 'Mitochondria', 'NF-E2-Related Factor 2', 'Phosphorylation', 'RN... | 28,687,409 | [['B01.050'], ['D08.811.913.696.620.682.725.800.158'], ['A11.251'], ['G04.043'], ['D12.644.276.500.700', 'D12.776.467.500.700', 'D12.776.543.287.700', 'D23.529.500.700'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.500.500.625', 'E04.936... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Renal endosomal phosphate (Pi) transport in normal and diabetic rats and response to chronic Pi deprivation. | Chronic renal adaptation to dietary deprivation of Pi is accompanied by increased Na+/Pi co-transport across the brush border membrane of the renal proximal tubule. The increased activity of this co-transport system depends on de novo protein synthesis and insulin. The present study used normal and diabetic rats to det... | ['Animals', 'Biological Transport', 'Blotting, Western', 'Diabetes Mellitus, Experimental', 'Endosomes', 'Hypoglycemic Agents', 'Insulin', 'Male', 'Microvilli', 'Phosphates', 'Phosphorus', 'Phosphorus, Dietary', 'Proline', 'Rats', 'Rats, Sprague-Dawley', 'Sodium', 'Urine'] | 9,075,331 | [['B01.050'], ['G03.143'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['A11.284.430.214.190.875.190.880.337'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A11.2... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of size hierarchy on surfacing behaviour and conversion rate in an air-breathing fish Channa striatus. | Effects of size hierachy on surfacing behaviour and food conversion rate in relation to density and feeding frequency were studied in Channa striatus. In general, crowding increased surfacing frequency in all the weight classes, but affected the food conversion rate of small individuals alone. At any tested density, co... | ['Animals', 'Behavior, Animal', 'Body Weight', 'Crowding', 'Energy Metabolism', 'Feeding Behavior', 'Fishes'] | 4,034,695 | [['B01.050'], ['F01.145.113'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['F01.145.875.281'], ['G03.295'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.493']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The age-dependent loss of cells from the rear of Dictyostelium discoideum slug is not tip controlled. | Young slugs of the cellular slime mould Dictyostelium discoideum drop small numbers of individual amoebae (approximately 10/mm) in the slime trail. With increased time of migration, slugs develop trailing tails and leave clumps of cells in their slime trails. Using reciprocal transplants between tips of young and old s... | ['Animals', 'Cell Count', 'Dictyostelium', 'Locomotion', 'Time Factors'] | 7,264,552 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['B01.046.550.200.300'], ['G07.568.500', 'G11.427.410.568'], ['G01.910.857']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insulin infusion reduces hepatocyte growth factor in lean humans. | OBJECTIVE: Plasma Hepatocyte Growth Factor (HGF) is significantly elevated in obesity and may contribute to vascular disease, metabolic syndrome or cancer in obese individuals. The current studies were done to determine if hyperinsulinemia increases plasma HGF.MATERIALS/METHODS: Twenty-two participants (10 women/12 men... | ['Adolescent', 'Adult', 'Body Mass Index', 'Down-Regulation', 'Female', 'Glucose Clamp Technique', 'Hepatocyte Growth Factor', 'Humans', 'Infusion Pumps', 'Insulin', 'Insulin Resistance', 'Male', 'Middle Aged', 'Thinness', 'Young Adult'] | 23,190,875 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['D12.644.276.374.420', 'D12.776.467.374.420', 'D23.529.374.420'], ['B01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[4-chloro-m-cresol-induced contractures of skeletal muscle specimen from patients at risk for malignant hyperthermia]. | PURPOSE: 4-chloro-m-cresol (4-CmC), commonly used as preservative, has been shown to induce contractures in skeletal muscle specimens from individuals susceptible to malignant hyperthermia (MH). It has been suggested that a defect of the calcium release channel of the skeletal muscle sarcoplasmic reticulum (ryanodine r... | ['Adolescent', 'Adult', 'Calcium', 'Child', 'Child, Preschool', 'Cresols', 'Culture Techniques', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Male', 'Malignant Hyperthermia', 'Middle Aged', 'Muscle Contraction', 'Prospective Studies', 'Risk Factors', 'Ryanodine Receptor Calcium Release Channel'] | 9,417,254 | [['M01.060.057'], ['M01.060.116'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['M01.060.406'], ['M01.060.406.448'], ['D02.455.426.559.389.657.239'], ['E05.481.500'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505.700', 'C23.550.767.600'], ['M01.060.116... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Multidisciplinary approach to the management of head and neck arteriovenous malformations. | Arteriovenous malformations (AVM) of the head and neck are quite rare in contrast to low-flow vascular anomalies, but often present with significant haemorrhage or cosmetic defects. Treatment of these high-flow vascular anomalies is hazardous and has a predictably high incidence of recurrence if not managed correctly. ... | ['Adolescent', 'Adult', 'Angiography', 'Arteriovenous Malformations', 'Carotid Artery, External', 'Child', 'Combined Modality Therapy', 'Embolization, Therapeutic', 'Face', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Neck'] | 7,717,646 | [['M01.060.057'], ['M01.060.116'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['A07.015.114.186.200.210'], ['M01.060.406'], ['E02.186'], ['E02.520.360', 'E02.926.500'], ['A01.456.505'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.45... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vivo binding of 3H-etorphine in morphine-dependent rats. | The opiate agonist 3H-etorphine was used to search for potential changes in in vivo opiate receptor binding in rats following chronic exposure to morphine sulfate. A rapid filtration method was employed to allow assessment of in vivo binding; receptor dissociation in vitro following in vivo labeling was also measured. ... | ['Animals', 'Etorphine', 'Female', 'Humans', 'Morphinans', 'Morphine Dependence', 'Rats', 'Rats, Inbred Strains', 'Receptors, Opioid', 'Tritium'] | 6,292,637 | [['B01.050'], ['D03.132.577.249.270', 'D03.605.497.320', 'D03.633.400.686.320', 'D04.615.723.795.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.577.249', 'D03.605.497', 'D03.633.400.686', 'D04.615.723.795'], ['C25.775.643.500.600', 'F03.900.647.500.600'], ['B01.050.150.900.649.313.992.635.505.700'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Motor training effects on recovery of function after striatal lesions and striatal grafts. | Environment, training, and experience can influence plasticity and recovery of function after brain damage. However, it is less well known whether, and how, such factors influence the growth, integration, and functional recovery provided by neural grafts placed within the brain. To explore this process, rats were pretr... | ['Animals', 'Apomorphine', 'Brain Tissue Transplantation', 'Central Nervous System Stimulants', 'Dextroamphetamine', 'Dopamine Agonists', 'Functional Laterality', 'Graft Survival', 'Learning', 'Male', 'Motor Skills', 'Neostriatum', 'Neuronal Plasticity', 'Neurotoxins', 'Psychomotor Performance', 'Quinolinic Acid', 'Rat... | 14,637,098 | [['B01.050'], ['D03.132.098.038.290', 'D03.633.100.531.085.030.290', 'D03.633.400.095.290'], ['E02.095.147.725.090', 'E04.525.090', 'E04.936.580.090'], ['D27.505.696.282', 'D27.505.954.427.220'], ['D02.092.471.683.152.110.200'], ['D27.505.519.625.150.151', 'D27.505.696.577.150.151'], ['F02.830.297.425', 'G11.561.225.42... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
What affects completion of the scholarly project? A survey of RANZCP trainees. | OBJECTIVE: To explore trainee perception of what facilitates or delays completion of the RANZCP Scholarly Project (SP).METHOD: Of 182 currently registered New Zealand trainees, 33 (18%) completed an online questionnaire and three open-ended questions.RESULTS: Most trainees agreed or strongly agreed that having protecte... | ['Adult', 'Biomedical Research', 'Competency-Based Education', 'Education, Medical, Graduate', 'Female', 'Humans', 'Male', 'Middle Aged', 'New Zealand', 'Psychiatry', 'Societies, Medical'] | 29,737,192 | [['M01.060.116'], ['H01.770.644.145'], ['I02.158.210'], ['I02.358.337.350', 'I02.358.399.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.639.760.747', 'Z01.678.100.747'], ['F04.096.544', 'H02.403.690'], ['N03.540.828.589']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Single-dose half-body irradiation for palliation of multiple bone metastases from solid tumors. Final Radiation Therapy Oncology Group report. | This is the final analysis of Protocol #78-10 which explored increasing single-doses of half-body irradiation (HBI) in patients with multiple (symptomatic) osseous metastases. When given as palliation, HBI was found to relieve pain in 73% of the patients. In 20% of the patients the pain relief was complete; over two th... | ['Bone Neoplasms', 'Clinical Trials as Topic', 'Gastrointestinal Diseases', 'Hematologic Diseases', 'Humans', 'Length of Stay', 'Narcotics', 'Pain', 'Palliative Care', 'Premedication', 'Radiotherapy', 'Radiotherapy Dosage', 'Radiotherapy, High-Energy', 'Time Factors'] | 2,423,225 | [['C04.588.149', 'C05.116.231'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C06.405'], ['C15.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['D27.505.696.277.600', 'D27.505.696.663.850.014.760', 'D27.505.954.427.040.550', 'D27.50... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The impact of core biopsy fragmentation in prostate cancer. | OBJECTIVES: Since accurate tumor localization and quantification are essential requisites avoiding prostate cancer overtreatment, we analyzed the impact of core fragmentation and the relation between core biopsy taken and pathological information in regard to cancer extension and aggressiveness (Gleason score).METHODS:... | ['Aged', 'Biopsy, Needle', 'Humans', 'Male', 'Middle Aged', 'Prostatic Neoplasms'] | 20,221,804 | [['M01.060.116.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.945.440.770', 'C12.294.260.750',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Refractive change in response to acute hyperbaric stress in refractive surgery patients. | PURPOSE: To determine whether acute hyperbaric stress affects visual acuity or refractive power after keratorefractive surgery.SETTING: Clinical multiplace hyperbaric chamber and ophthalmology clinic, University of California, San Diego, California, USA.METHODS: This prospective convenience sample study included 3 grou... | ['Adult', 'Atmospheric Pressure', 'Cornea', 'Diving', 'Eyeglasses', 'Humans', 'Keratomileusis, Laser In Situ', 'Keratotomy, Radial', 'Laser Therapy', 'Middle Aged', 'Myopia', 'Reference Values', 'Refraction, Ocular', 'Stress, Physiological', 'Visual Acuity'] | 12,231,314 | [['M01.060.116'], ['G16.500.750.274', 'N06.230.300.100.185'], ['A09.371.060.217'], ['I03.450.642.845.945.500.110', 'N06.230.150.150'], ['E07.632.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594.480.750', 'E04.014.520.480.750', 'E04.378.500.750', 'E04.540.825.437.374'], ['E04.540.825.550'], ['E02.59... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Risk-Benefit Profile of Longer-Than-1-Year Dual-Antiplatelet Therapy Duration After Drug-Eluting Stent Implantation in Relation to Clinical Presentation. | BACKGROUND: We sought to determine whether the risks and benefits of prolonging dual-antiplatelet therapy (DAPT) beyond 1 year after drug-eluting stent implantation depend on clinical presentation in a meta-analysis of randomized controlled trials.METHODS AND RESULTS: Randomized controlled trials comparing ?1- versus >... | ['Acute Coronary Syndrome', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Drug-Eluting Stents', 'Hemorrhage', 'Humans', 'Myocardial Infarction', 'Myocardial Ischemia', 'Percutaneous Coronary Intervention', 'Platelet Aggregation Inhibitors', 'Randomized Controlled Trials as Topic', 'Risk Assessment', 'Ri... | 30,871,353 | [['C14.280.647.124', 'C14.907.585.124'], ['E02.319.283'], ['E02.319.310'], ['E07.695.750.500'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['C14.280.647', 'C14.907.585'], ['E04.100.814.529.968', 'E04.502.382.968... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effective behavioral intervention strategies using mobile health applications for chronic disease management: a systematic review. | BACKGROUND: Mobile health (mHealth) has continuously been used as a method in behavioral research to improve self-management in patients with chronic diseases. However, the evidence of its effectiveness in chronic disease management in the adult population is still lacking. We conducted a systematic review to examine t... | ['Behavior Therapy', 'Chronic Disease', 'Disease Management', 'Health Promotion', 'Humans', 'Mobile Applications', 'Outcome Assessment, Health Care', 'Randomized Controlled Trials as Topic', 'Telemedicine'] | 29,458,358 | [['F04.754.137'], ['C23.550.291.500'], ['N04.590.607'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.900.685'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Risk Factors and Predictors of Cardiac Erosion Discovered from 12 Japanese Patients Who Developed Erosion After Atrial Septal Defect Closure Using Amplatzer Septal Occluder. | Cardiac erosion is a rare serious complication following Amplatzer septal occluder (ASO) placement for atrial septal defect. Although multiple risk factors have been found, a useful predictor to prevent it has not been established yet. In 12 patients who developed erosion between 2005 and 2016 in Japan, we retrospectiv... | ['Adult', 'Balloon Occlusion', 'Child', 'Echocardiography, Transesophageal', 'Female', 'Heart Injuries', 'Heart Septal Defects, Atrial', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Septal Occluder Device', 'Treatment Outcome'] | 31,732,763 | [['M01.060.116'], ['E02.148.106', 'E02.520.392.500', 'E02.926.500.074', 'E05.157.063'], ['M01.060.406'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['C26.891.375'], ['C14.240.400.560.375', 'C14.280.400.560.375', 'C16.131.240.400.560.375'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Multiple pudendal sensory pathways reflexly modulate bladder and urethral activity in patients with spinal cord injury. | PURPOSE: Electrical stimulation of pudendal afferents can evoke reflex bladder contractions with relaxation of the external urethral sphincter in cats. This voiding reflex is mediated by pudendal sensory fibers innervating the penile and prostatic urethra that engage spinal and spinobulbospinal micturition pathways, re... | ['Adult', 'Afferent Pathways', 'Aged', 'Chronic Disease', 'Electric Stimulation', 'Electromyography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Muscle Contraction', 'Muscle, Smooth', 'Reflex', 'Sampling Studies', 'Sensory Thresholds', 'Spinal Cord Injuries', 'Urethra', 'Urinary Bladder', 'Urinary Bladder, Neurogenic'... | 21,168,860 | [['M01.060.116'], ['A08.612.220'], ['M01.060.116.100'], ['C23.550.291.500'], ['E05.723.402'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G11.427.494'], ['A02.633.570', 'A10.690.467'], ['E01.370.376.550.650', 'E01.370.600.550.650', 'F02.830.702', 'G11.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oligodendrocyte injury in multiple sclerosis: a role for p53. | Multiple sclerosis (MS) is a neurological disorder characterized by myelin destruction and a variable degree of oligodendrocyte death. We have previously shown that overexpression of the transcription factor p53 can induce oligodendrocyte apoptosis. We investigated the mechanism of p53-induced apoptosis using primary c... | ['Adenoviridae', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Caspases', 'Cells, Cultured', 'Fas Ligand Protein', 'Gene Transfer Techniques', 'Humans', 'Ligands', 'Membrane Glycoproteins', 'Multiple Sclerosis', 'Oligodendroglia', 'Receptors, TNF-Related Apoptosis-Inducing Ligand', 'Receptors, Tumor Necrosis Factor', ... | 12,694,389 | [['B04.280.030'], ['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['A11.251'], ['D12.644.276.374.750.249', 'D12.776.395.550.312', 'D12.776.467.374.750.249', 'D12.776.543.550.312', 'D23.529.374.750.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of the promotion of fruit and vegetables on their consumption in the workplace. | OBJECTIVE: To evaluate the impact of activities promoting the consumption of fruit and vegetables (FV) in the workplace.METHODS: Intervention study with historical control group conducted in a public company in Rio de Janeiro, Southeastern Brazil, between 2007 and 2009. It consisted of three stages: (a) baseline, which... | ['Adult', 'Brazil', 'Dietary Services', 'Feeding Behavior', 'Female', 'Fruit', 'Health Promotion', 'Humans', 'Male', 'Occupational Health', 'Vegetables', 'Workplace'] | 23,703,127 | [['M01.060.116'], ['Z01.107.757.176'], ['N02.421.242'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.400.525'], ['B01.650.160.956', 'B01.650.510.956', 'G07.203.... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[First comparisons with laser vibrometry measurements and computer simulation of ear ossicle movements]. | The dynamic behavior of the ossicular chain is very complex and is frequency-dependent. To date, this has still not been fully investigated or understood. There remains a lack of measurement procedures to pick up the motion of the ossicles and ear drum simultaneously with sufficient resolution. The presented paper repo... | ['Computer Simulation', 'Ear Ossicles', 'Fourier Analysis', 'Hearing', 'Humans', 'Laser-Doppler Flowmetry', 'Mathematics', 'Physical Stimulation', 'Reference Values', 'Signal Processing, Computer-Assisted', 'Stapes', 'Vibration'] | 9,340,336 | [['L01.224.160'], ['A09.246.397.247'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.370.475', 'E05.830.500'], ['H01.548'], ['E05.723'], ['E05.978.810'], ['L01.224.800'], ['A09.246.397.247.806'], ['G01.374.930... | ['Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Chromosomes of lymph node metastases derived from Ehrlich ascites carcinoma cells inoculated into rats. | The inoculation of Ehrlich ascites carcinoma cells in irradiated and cortisone-treated rats induced an ascitic tumor and lymph node metastases. Chromosome banding analysis showed that metastatic lymph nodes are composed of Ehrlich tumor cells and normal rat metaphases, derived from reactive host cells. | ['Animals', 'Carcinoma, Ehrlich Tumor', 'Chromosomes', 'Cricetinae', 'Humans', 'Hybridization, Genetic', 'Lymphatic Metastasis', 'Metaphase', 'Polyploidy', 'Rats'] | 146,329 | [['B01.050'], ['C04.557.470.200.200', 'C04.619.169'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.820.150.390', 'G05.090.390'], ['C04.697.650.560', 'C23.550.727.650.560'], ['G04.144.220.220.687.625', '... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Concordance networks and application to clustering cancer symptomology. | Symptoms of complex illnesses such as cancer often present with a high degree of heterogeneity between patients. At the same time, there are often core symptoms that act as common drivers for other symptoms, such as fatigue leading to depression and cognitive dysfunction. These symptoms are termed bridge symptoms and w... | ['Breast Neoplasms', 'Female', 'Humans', 'Models, Biological', 'Syndrome'] | 29,538,418 | [['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['C23.550.288.500']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluating the quality of self-reports of hypertension and diabetes. | Increasingly, researchers and health specialists are obtaining information on chronic illnesses from self-reports. This study validates self-reports of two major health conditions, hypertension and diabetes, based on a recent survey in Taiwan (SEBAS 2000). These data, based on a large, nationally representative sample ... | ['Age Distribution', 'Aged', 'Diabetes Mellitus', 'Female', 'Follow-Up Studies', 'Health Surveys', 'Humans', 'Hypertension', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Odds Ratio', 'Self Disclosure', 'Sex Distribution', 'Taiwan'] | 12,654,409 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['C18.452.394.750', 'C19.246'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A special report: four-year study of a boy with combined immune deficiency maintained in strict reverse isolation from birth. | A 4-year study of a boy with combined immune deficiency is presented, and the impact of this disease on various aspects of his growth and development is examined. There is no evidence of immune deficiency in either parent or in the genetic background on the maternal side. Three children of a brother of the mother's fat... | ['Child Behavior', 'Child Development', 'Child Nutritional Physiological Phenomena', 'Child, Preschool', 'Cholesterol, Dietary', 'Germ-Free Life', 'Humans', 'Immunity', 'Immunologic Deficiency Syndromes', 'Infant', 'Infant Nutritional Physiological Phenomena', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Infection ... | 401,538 | [['F01.145.179'], ['F01.525.200', 'G07.345.374.750'], ['G07.203.650.220'], ['M01.060.406.448'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['G06.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['C20.673'], ['M01.060.703'], ['G07.203.650.220.500'], ['M01.060.703.520']... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of alcohol consumption on mortality in patients with Type 2 diabetes mellitus. | AIMS/HYPOTHESIS: Moderate alcohol intake has been associated with increased life expectancy due to reduced mortality from cardiovascular disease. We prospectively examined the effects of alcohol consumption on mortality in Type 2 diabetic patients in Switzerland.METHODS: A total of 287 patients with Type 2 diabetes mel... | ['Adult', 'Alcohol Drinking', 'Coronary Disease', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Survival Analysis', 'Switzerland', 'Time Factors'] | 14,508,652 | [['M01.060.116'], ['F01.145.317.269'], ['C14.280.647.250', 'C14.907.585.250'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.099.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Aculeatin, a coumarin derived from Toddalia asiatica (L.) Lam., enhances differentiation and lipolysis of 3T3-L1 adipocytes. | Toddalia asiatica (L.) Lam. (T. asiatica) has been utilized traditionally for medicinal purposes such as the treatment of diabetes. Currently, the extract is considered to be a good source of anti-diabetic agents, but the active compounds have yet to be identified. In this study, we investigated the effects of fraction... | ['3T3-L1 Cells', 'Adipocytes', 'Animals', 'Cell Differentiation', 'Coumarins', 'Cyclohexanones', 'Lipolysis', 'Mice', 'Plant Extracts', 'Rutaceae'] | 25,445,590 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['A11.329.114'], ['B01.050'], ['G04.152'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['D02.455.426.392.368.367.340', 'D02.522.400'], ['G02.111.534', 'G03.458.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['D20.215.784.500', 'D26.667'], ['B01.650.940.8... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subjective and objective evaluation of noise management algorithms. | PURPOSE: To measure the subjective and objective improvement of speech intelligibility in noise offered by a commercial hearing aid that uses a fully adaptive directional microphone and a noise reduction algorithm that optimizes the Speech Intelligibility Index (SII).RESEARCH DESIGN: Comparison of results on the Hearin... | ['Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Audiometry, Speech', 'Female', 'Hearing Aids', 'Hearing Loss, Bilateral', 'Hearing Loss, Sensorineural', 'Humans', 'Male', 'Middle Aged', 'Noise', 'Speech Perception'] | 19,927,672 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['E01.370.382.375.060.060'], ['E07.305.906.500', 'E07.814.458'], ['C09.218.458.341.374', 'C10.597.751.418.341.374', 'C23.888.592.763.393.341.374'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Effect of differences in MIC values on clinical outcomes in patients with bloodstream infections caused by gram-negative organisms treated with levofloxacin. | Emerging evidence suggests that current fluoroquinolone dosing strategies may be inadequate to treat bloodstream infections caused by organisms classified as sensitive. This study sought to determine if differences in MICs for levofloxacin-susceptible gram-negative organisms correlate with differences in patient outcom... | ['Adult', 'Aged', 'Anti-Bacterial Agents', 'Cohort Studies', 'Female', 'Gram-Negative Bacteria', 'Gram-Negative Bacterial Infections', 'Humans', 'Length of Stay', 'Levofloxacin', 'Male', 'Microbial Sensitivity Tests', 'Middle Aged', 'Ofloxacin', 'Retrospective Studies', 'Treatment Outcome'] | 19,075,047 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B03.440'], ['C01.150.252.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['D03.633.100.810.835.322.500.500'], ['E01.370.225... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pregnancy-induced changes in central response to atrial distension mimicked by progesterone metabolite. | In virgin female rats, atrial distension (an index of blood volume expansion) causes an increase in c-fos expression in the paraventricular nucleus of the lateral hypothalamus. During pregnancy, this response is markedly attenuated. We tested the effects of 3alpha-hydroxy-5alpha-pregnan-20-one (3alpha-OH-DHP) on activa... | ['Animals', 'Atrial Function', 'Female', 'Neurons', 'Paraventricular Hypothalamic Nucleus', 'Pregnancy', 'Pregnancy, Animal', 'Pregnanolone', 'Progesterone', 'Proto-Oncogene Proteins c-fos', 'Rats', 'Rats, Long-Evans'] | 9,843,876 | [['B01.050'], ['G09.330.040'], ['A08.675', 'A11.671'], ['A08.186.211.180.497.342.400', 'A08.186.211.200.317.357.342.400'], ['G08.686.784.769'], ['G08.686.784.769.498'], ['D04.210.500.745.640'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['D12.776.260.108.765', 'D12.776.624.664.70... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molybdenum cofactor deficiency presenting with severe metabolic acidosis and intracranial hemorrhage. | Molybdenum cofactor deficiency leads to combined deficiency of sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase enzyme activities. The major clinic symptom is intractable seizures seen soon after birth. No definite therapy is available. We report here a newborn with molybdenum cofactor deficiency-associate... | ['Acidosis, Lactic', 'Coenzymes', 'Dandy-Walker Syndrome', 'Female', 'Humans', 'Infant, Newborn', 'Intracranial Hemorrhages', 'Metabolism, Inborn Errors', 'Metalloproteins', 'Pteridines'] | 15,794,186 | [['C18.452.076.176.180'], ['D08.211'], ['C10.228.140.252.300', 'C10.228.140.602.500', 'C10.500.205', 'C16.131.666.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C10.228.140.300.535', 'C14.907.253.573', 'C23.550.414.913'], ['C16.320.565', 'C18.452.648'], ['D12.776.556'], ['D03.633.100.733... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A strategy for enhancing the transcriptional activity of weak cell type-specific promoters. | Cell type- and tissue-specific promoters play an important role in the development of site-selective vectors for gene therapy. A large number of highly specific promoters has been described, but their applicability is often hampered by their inefficient transcriptional activity. In this study, we describe a new strateg... | ['3T3 Cells', 'Animals', 'Cattle', 'Cell Line', 'Endothelium', 'Feedback', 'Gene Expression', 'Genetic Therapy', 'Genetic Vectors', 'Humans', 'Luciferases', 'Mice', 'Promoter Regions, Genetic', 'Sucrase-Isomaltase Complex', 'Transfection', 'von Willebrand Factor'] | 10,023,445 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['A10.272.491'], ['L01.906.394.211'], ['G05.297'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.517', 'D12.776.532.510'], ['B01.050.150.9... | ['Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Urinary cobalt as a measure of exposure in the hard metal industry. | Twenty-six workers in a hard metal manufacturing plant were monitored by cobalt urinary and ambient air measurements during the first month after summer holidays. Cobalt determinations were performed utilizing AAS, with a preliminary chelation and extraction procedure for urinary samples. Almost all personal ambient ai... | ['Air Pollutants, Occupational', 'Cobalt', 'Humans', 'Metals', 'Microclimate', 'Time Factors'] | 4,077,278 | [['D27.888.284.101.268'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.552'], ['G16.500.275.071.450', 'N06.230.300.100.250.450'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Organocatalytic conjugate addition of nitroalkanes to 3-ylidene oxindoles: a stereocontrolled diversity oriented route to oxindole derivatives. | An efficient and highly enantioselective Michael addition of nitroalkanes to 3-ylidene oxindoles is described, mediated by thiourea-based bifunctional organocatalysts. The stereochemistry at C(á) and C(â) centers is perfectly controlled, and the intermediate C-3 enolate is trapped with a second Michael acceptor. The de... | ['Alkanes', 'Catalysis', 'Indoles', 'Molecular Structure', 'Nitro Compounds', 'Stereoisomerism', 'Thiourea'] | 24,168,398 | [['D02.455.326.146'], ['G02.130'], ['D03.633.100.473'], ['G02.111.570', 'G02.466'], ['D02.640'], ['G02.607.445.682'], ['D02.065.950.898', 'D02.886.904']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The ontogeny of the alpha 2- and beta-adrenoreceptors in the brain following exposure to corticosterone during intrauterine development]. | Ontogenesis of alpha 2- and beta-adrenoreceptors in brain cortex of rats after corticosterone injections to their mothers on days 16 and 18 days of gestation was studied using 3H-clonidine and 3H-dihydroaoprenolol binding. After corticosterone treatment the level of beta-adrenoreceptors was decreased on day 7 but incre... | ['Animals', 'Cerebral Cortex', 'Clonidine', 'Corticosterone', 'Dihydroalprenolol', 'Female', 'Gestational Age', 'Male', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Rats', 'Rats, Inbred Strains', 'Receptors, Adrenergic, alpha', 'Receptors, Adrenergic, beta', 'Tritium'] | 1,665,903 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['D03.383.129.308.436.500'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['D02.033.100.624.698.055.200', 'D02.033.755.624.698.055.200', 'D02.092.063.624.698.055.200'], ['G07.345.500.325.235.968', 'G08.686.320'], ['G08.686.784.769'], ['C13.703.824.500'], ['B... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased Incidence of Thyroid Disease in Patients with Alopecia Areata: A Systematic Review and Meta-Analysis. | BACKGROUND: Alopecia areata (AA) is a common, clinically heterogeneous, immune-mediated, nonscarring hair loss disease with a pathogenesis that is not fully understood. The prevalence of thyroid disease is likely increased among individuals with AA. However, this association remains controversial.OBJECTIVE: To evaluate... | ['Alopecia Areata', 'Humans', 'Incidence', 'Prevalence', 'Risk', 'Thyroid Diseases'] | 31,618,741 | [['C17.800.329.937.122.147'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05.318.740... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Increased serum PCSK9 concentrations are associated with periodontal infection but do not correlate with LDL cholesterol concentration. | BACKGROUND: Periodontal disease increases the risk of atherothrombotic disease, and high concentrations of low density lipoprotein (LDL) cholesterol are considered to be involved; however, the underlying mechanisms are largely unknown. Recent studies demonstrated that proprotein convertase subtilisin/kexin type 9 (PCSK... | ['Adult', 'Antibodies, Bacterial', 'C-Reactive Protein', 'Case-Control Studies', 'Cholesterol, LDL', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Interleukin-6', 'Male', 'Middle Aged', 'Periodontitis', 'Porphyromonas gingivalis', 'Proprotein Convertase 9', 'Proprotein Convertases', 'Serine Endopeptidases',... | 22,001,517 | [['M01.060.116'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thymoma of the left thymic lobe with a contralateral small pleural implant successfully detected with diffusion-weighted MRI. | Thymoma is the most common primary neoplasm of the anterior mediastinum. At diagnosis, up to 40% of patients present with advanced disease. Because advanced thymomas receive neoadjuvant chemotherapy, diagnostic imaging is crucial to plan the correct treatment. For characterizing thymomas, CT is the first choice modalit... | ['Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Chemotherapy, Adjuvant', 'Contrast Media', 'Diagnosis, Differential', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Myasthenia Gravis', 'Neoadjuvant Therapy', 'Neoplasm Staging', 'Pleural Neoplasms', 'Positron-Emission... | 25,702,681 | [['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186.170', 'E02.319.170'], ['D27.505.259.500', 'D27.720.259'], ['E01.171'], ['E01.370.350.825.500.150'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.550.500', 'C04.730.856.490', 'C10.114.656', 'C10.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunoelectrophoretic differentiation of alpha-fetoprotein in disorders with elevated serum alpha-fetoprotein levels or during pregnancy. | Our study aims to make differential diagnosis by immunoelectrophoresis for some common conditions with elevated levels of serum alpha-fetoprotein (AFP). One hundred and nine cases with elevated AFP levels were included in this study: yolk sac tumor (n = 8), hepatocellular carcinoma (n = 26), gastric cancer (n = 12), ch... | ['Biomarkers, Tumor', 'Carcinoma, Hepatocellular', 'Chronic Disease', 'Diagnosis, Differential', 'Endodermal Sinus Tumor', 'Female', 'Hepatitis', 'Humans', 'Immunoelectrophoresis', 'Liver Neoplasms', 'Neoplasms', 'Pregnancy', 'Stomach Neoplasms', 'alpha-Fetoproteins'] | 7,492,383 | [['D23.101.140'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C23.550.291.500'], ['E01.171'], ['C04.557.465.510.350'], ['C06.552.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.645.350.350', 'E05.196.401.568', 'E05.200.812.735.645.350.350', '... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Ultrasonographic study on effects of Wendan Xiezhuo method in improving vascular endothelial diastolic function and atherosclerosis in hypertension patients with turbid-phlegm syndrome]. | OBJECTIVE: To observe the effect of Wendan Xiezhuo method (WXM) on carotid arteriosclerosis and vascular endothelial diastolic function in essential hypertension (EH) patients with turbid-phlegm syndrome (TPS).METHODS: Forty-three EH patients of medium and low risk with TPS were randomly assigned to two groups, the Wen... | ['Aged', 'Atherosclerosis', 'Carotid Arteries', 'Carotid Artery Diseases', 'Drugs, Chinese Herbal', 'Endothelium, Vascular', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Phytotherapy', 'Syndrome', 'Treatment Outcome', 'Ultrasonography'] | 17,302,058 | [['M01.060.116.100'], ['C14.907.137.126.307'], ['A07.015.114.186'], ['C10.228.140.300.200', 'C14.907.253.123'], ['D20.215.784.500.350', 'D26.335'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['E02.190.755'], ['C23.550.288.500'], ['E01.7... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation of rat ventral prostate basal and luminal epithelial cells by the STAPUT technique. | BACKGROUND: The prostatic epithelium consists principally of basal epithelial cells, luminal epithelial cells, and neuroendocrine cells. Several studies support the concept that among basal cells, a subpopulation of stem cells resides which is capable of giving rise to other stem cells, basal epithelial cells, and also... | ['Animals', 'Cell Culture Techniques', 'Cell Separation', 'Epithelial Cells', 'Male', 'Prostate', 'Rats', 'Rats, Sprague-Dawley'] | 10,517,875 | [['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['A11.436'], ['A05.360.444.575', 'A10.336.707'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The laparoscopic management of benign bowel fistulas. | BACKGROUND: The presence of a fistula has usually been a factor predicting high conversion and complication rates following laparoscopic procedures for Crohn's disease and diverticulitis.METHODS: We studied retrospective data collected from the medical case notes of patients. A single surgeon carried out all these proc... | ['Crohn Disease', 'Digestive System Surgical Procedures', 'Diverticulitis, Colonic', 'Female', 'Humans', 'Intestinal Fistula', 'Laparoscopy', 'Male', 'Retrospective Studies', 'Surgical Stapling'] | 15,554,280 | [['C06.405.205.731.500', 'C06.405.469.432.500'], ['E04.210'], ['C06.405.205.282.500.250', 'C06.405.469.158.587.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.267.550', 'C06.405.469.471', 'C23.300.575.185.550'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.7... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Elevated monocyte distribution width in COVID-19 patients: The contribution of the novel sepsis indicator. | INTRODUCTION: Interesting results regarding the contribution of MDW (Monocyte Distribution Width) in the Infectious Disease Unit have been reported. An observational study is ongoing at San Donato Hospital with the aim to evaluate the contribution of MDW in the diagnostic pathway in adult patients entering in the ED se... | ['Adult', 'Aged', 'Betacoronavirus', 'COVID-19', 'Cell Size', 'Clinical Laboratory Techniques', 'Coronavirus Infections', 'Female', 'Humans', 'Male', 'Middle Aged', 'Monocytes', 'Pandemics', 'Pneumonia, Viral', 'SARS-CoV-2', 'Sepsis'] | 32,504,637 | [['M01.060.116'], ['M01.060.116.100'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['G04.325'], ['E01.370.225', 'E05.200'], ['C01.925.782.600.550.200'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association of Ovarian Tumor â2-Adrenergic Receptor Status with Ovarian Cancer Risk Factors and Survival. | BACKGROUND: The â2-adrenergic signaling pathway mediates the effects of chronic stress on ovarian cancer progression in mouse models. The relevance of this pathway to human ovarian cancer remains unknown.METHODS: We assessed tumor expression of â2-adrenergic receptor (ADRB2) using tissue microarrays in 237 ovarian canc... | ['Aged', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Menopause', 'Middle Aged', 'Ovarian Neoplasms', 'Parity', 'Receptors, Adrenergic, beta-2', 'Risk Factors', 'Signal Transduction'] | 27,587,791 | [['M01.060.116.100'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.157.500', 'G08.686.841.249.500'], ['M01.060.116.630'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['G08.686.677', 'G08.686.784.769.472', 'N06.850.490.812.600'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Assessment of mental status at the drivers of the vehicles after using alcohol or drunk driving]. | UNLABELLED: Alcohol changes the behavior and works toward making behavior carrying a risk, such as driving in the state of intoxication, work at height, using machines requiring full medical fitness, breach of security at work. The aim of the study was to present a preliminary assessment of the mental state of drivers ... | ['Adult', 'Aged', 'Alcohol Drinking', 'Automobile Driving', 'Comorbidity', 'Depression', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Personality Disorders', 'Poland', 'Risk-Taking', 'Surveys and Questionnaires', 'Young Adult'] | 23,437,702 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.317.269'], ['I03.125'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['F03.675'], ['Z01.542.248.679'], ['F01.145.722'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Filamentous contacts: the ultrastructure and three-dimensional organization of specialized non-synaptic interneuronal appositions in thalamic relay nuclei. | Filamentous contacts are non-synaptic interneuronal junctions characteristic of thalamic relay nuclei. Symmetrical filamentous contacts occur between two dendrites, two somata or a dendrite and a soma; asymmetrical filamentous contacts occur between axon terminals and dendrites, or occasionally somata, chiefly between ... | ['Intercellular Junctions', 'Neurons', 'Synapses', 'Thalamic Nuclei'] | 9,042,771 | [['A11.284.149.165.420'], ['A08.675', 'A11.671'], ['A08.850', 'A11.284.149.165.420.780'], ['A08.186.211.200.317.826.701']] | ['Anatomy [A]'] | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation. | Stimulation of GCN4 mRNA translation due to phosphorylation of the alpha-subunit of initiation factor 2 (eIF2) by its specific kinase, GCN2, requires binding of uncharged tRNA to a histidyl-tRNA synthetase (HisRS)-like domain in GCN2. GCN2 function in vivo also requires GCN1 and GCN20, but it was unknown whether these ... | ['ATP-Binding Cassette Transporters', 'Alleles', 'Amino Acids', 'Blotting, Western', 'Caenorhabditis elegans Proteins', 'Carrier Proteins', 'DNA-Binding Proteins', 'Enzyme Activation', 'Eukaryotic Initiation Factor-2', 'Fungal Proteins', 'Glutathione Transferase', 'Peptide Elongation Factors', 'Phenotype', 'Precipitin ... | 10,775,272 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['G05.360.340.024.340.030'], ['D12.125'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.419.500'], ['D12.776.157'], ['D12.776.260'], ['G02.111.263', 'G03.328'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sequence variation in ligand binding sites in proteins. | BACKGROUND: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of these proteins can be structurally or functionally categorized from sequence conservation alone. In contrast, little attention has been given to... | ['Binding Sites', 'Conserved Sequence', 'Ligands', 'Nuclear Proteins', 'Peptides', 'Receptors, Cell Surface', 'Repetitive Sequences, Nucleic Acid', 'Sequence Analysis, Protein'] | 16,194,281 | [['G02.111.570.120'], ['G02.111.570.580'], ['D27.720.470.480'], ['D12.776.660'], ['D12.644'], ['D12.776.543.750'], ['G02.111.570.080.708', 'G05.360.080.708'], ['E05.393.760.705']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavioral changes in dogs associated with the development of idiopathic epilepsy. | OBJECTIVES: The aim of the study was to demonstrate behavioral changes with the development of epilepsy in dogs, a species proposed as a naturally occurring animal model for human epilepsy.METHODS: Owners of dogs diagnosed with idiopathic epilepsy (n=80) completed a modified, previously-validated behavioral and seizure... | ['Animals', 'Anticonvulsants', 'Behavior, Animal', 'Dogs', 'Epilepsy', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Male', 'Sex Factors', 'Species Specificity', 'Surveys and Questionnaires'] | 21,531,631 | [['B01.050'], ['D27.505.954.427.080'], ['F01.145.113'], ['B01.050.150.900.649.313.750.250.216.200'], ['C10.228.140.490'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N05.715.350.675', 'N06.850.490.875'], ['G16.824'], ['E05.318.308.980', 'N05.715.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Voltage-dependent block by strychnine of N-methyl-D-aspartic acid-activated cationic channels in rat cortical neurons in culture. | Single-channel currents were recorded by means of the patch clamp method in outside-out patches excised from rat cortical neurons in primary culture. The excitatory amino acid N-methyl-D-aspartic acid activated mainly 40-50 pS conductance channels. Channel opening durations were characterized by a series of rapid openi... | ['Allosteric Regulation', 'Animals', 'Cations', 'Cells, Cultured', 'Cerebral Cortex', 'Drug Interactions', 'Glycine', 'Ion Channels', 'Kainic Acid', 'Magnesium', 'Oxadiazoles', 'Quisqualic Acid', 'Rats', 'Receptors, N-Methyl-D-Aspartate', 'Receptors, Neurotransmitter', 'Strychnine'] | 2,457,795 | [['G02.111.044'], ['B01.050'], ['D01.248.497.300'], ['A11.251'], ['A08.186.211.200.885.287.500'], ['G07.690.773.968'], ['D12.125.481'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['D03.383.773.400'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['D03.383.129.462.580'], ['D03.38... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Does the renin-angiotensin system determine the renal and systemic hemodynamic response to sodium in patients with essential hypertension? | Many patients with essential hypertension respond to a high dietary sodium intake with a rise in blood pressure. Experimental evidence suggests that the renal hemodynamic response to sodium determines, at least partially, this rise in blood pressure. Our aim was to clarify the role of the renin-angiotensin system in th... | ['Adult', 'Antihypertensive Agents', 'Blood Pressure', 'Cross-Over Studies', 'Diet, Sodium-Restricted', 'Female', 'Hemodynamics', 'Humans', 'Hypertension', 'Imidazoles', 'Male', 'Middle Aged', 'Reference Values', 'Regional Blood Flow', 'Regression Analysis', 'Renal Circulation', 'Renin', 'Renin-Angiotensin System', 'So... | 8,567,042 | [['M01.060.116'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E02.642.249.290', 'G07.203.650.240.290'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['D03.383.129.308'], ['M01.060.116.630'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Complete comparative genomic analysis of two field isolates of Mamestra configurata nucleopolyhedrovirus-A. | A second genotype of Mamestra configurata nucleopolyhedrovirus-A (MacoNPV-A), variant 90/4 (v90/4), was identified due to its altered restriction endonuclease profile and reduced virulence for the host insect, M. configurata, relative to the archetypal genotype, MacoNPV-A variant 90/2 (v90/2). To investigate the geneti... | ['Animals', 'Base Sequence', 'Genetic Variation', 'Genome, Viral', 'Genotype', 'Larva', 'Molecular Sequence Data', 'Nucleopolyhedroviruses', 'Psychodidae', 'Sequence Alignment', 'Sequence Homology, Nucleic Acid', 'Species Specificity'] | 15,604,435 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.365'], ['G05.360.340.358.840'], ['G05.380'], ['B05.500.500', 'G07.345.500.550.500.500'], ['L01.453.245.667'], ['B04.280.065.500', 'B04.525.100.500'], ['B01.050.500.131.617.720.500.500.750.781'], ['E05.393.751'], ['G02.111.810.550', 'G05.810.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The lysine analog L-oxalysine is an inhibitor of RNA synthesis. | 1. The lysine analog L-4-oxalysine was found to be a potent inhibitor of RNA synthesis in Candida albicans. 2. The compound was a weak inhibitor of protein synthesis and DNA synthesis was not affected. 3. The inhibition of RNA synthesis was reversed by L-lysine but not D-lysine. 4. The decrease in the level of newly sy... | ['Amino Acids', 'Amino Acids, Dicarboxylic', 'Candida albicans', 'DNA, Fungal', 'Electrophoresis, Agar Gel', 'Fungal Proteins', 'Kinetics', 'Lysine', 'RNA, Fungal'] | 1,582,527 | [['D12.125'], ['D12.125.119'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['D13.444.308.300'], ['E05.196.401.153', 'E05.301.300.100'], ['D12.776.354'], ['G01.374.661', 'G02.111.490'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['D13.444.735.500']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum concentration of integrin-linked kinase in malignant pleural mesothelioma and after asbestos exposure. | OBJECTIVES: Integrin-linked kinase (ILK) is an intracellular protein implicated in chronic inflammation and neoplastic transformation. In a recently accomplished pilot study, we showed that ILK can be detected in the serum of patients with benign and malignant chest diseases, including malignant pleural mesothelioma (M... | ['Aged', 'Air Pollutants, Occupational', 'Analysis of Variance', 'Asbestos', 'Case-Control Studies', 'Diagnosis, Differential', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Male', 'Mesothelioma', 'Middle Aged', 'Occupational Exposure', 'Pleural Neoplasms', 'Protein-Serine-Threonine Kinases', 'ROC Curve', '... | 23,045,294 | [['M01.060.116.100'], ['D27.888.284.101.268'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D01.578.725.050', 'D01.837.725.700.760.070'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.171'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.17... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of Toxoplasma gondii oocysts in environmental samples from public schools. | The number of Toxoplasma gondii oocysts that can be found in random environmental samples is probably low; in addition, these cysts may be confused with Hammondia spp. and Neospora spp. oocysts. The aim of the present work was to evaluate the presence of T. gondii oocysts in the soil of public elementary schools in the... | ['Animals', 'Biological Assay', 'Brazil', 'Immunohistochemistry', 'Mice', 'Oocysts', 'Predictive Value of Tests', 'Schools', 'Sensitivity and Specificity', 'Soil', 'Toxoplasma', 'Toxoplasmosis'] | 20,347,524 | [['B01.050'], ['E05.091'], ['Z01.107.757.176'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', ... | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
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