Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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In-vitro activity of ofloxacin against Chlamydia trachomatis. | The in-vitro activity of ofloxacin was evaluated against recently isolated Chlamydia trachomatis strains from patients suffering from non-gonococcal urethritis. The minimal inhibitory concentration (MIC) proved to be 1 mg/l against 8 of the 10 strains assayed (the MICs for the other two strains were 0.5 and 2 mg/l). Th... | ['Chlamydia trachomatis', 'Microbial Sensitivity Tests', 'Ofloxacin'] | 2,809,689 | [['B03.440.190.190.190.750'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D03.633.100.810.835.322.500']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Remote monitoring of health status of the elderly at home. A multidisciplinary project on aging at the University of New South Wales. | This paper discusses the design and implementation of a multidisciplinary research project and associated field trials to test the hypothesis that functional health status amongst the elderly can be accurately determined remotely by continuously monitoring relatively simple parameters that measure the interaction betwe... | ['Activities of Daily Living', 'Aged', 'Baths', 'Clinical Trials as Topic', 'Community Health Services', 'Computer Communication Networks', 'Cooking', 'Cost Control', 'Cost-Benefit Analysis', 'Health Services for the Aged', 'Health Status', 'Home Care Services', 'Humans', 'Monitoring, Physiologic', 'New South Wales', '... | 8,847,123 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['E02.056.110'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['N02.421.143'], ['L01.224.230.110'], ['J01.576.423.200.200'], ['N03.219.151.160'], ['N03.219.151.125'], ['N02.421.320'], ['I01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Humanities [K]', 'Psychiatry and ... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Influence of depression and HIV serostatus on the neuropsychological performance of injecting drug users. | Depression is common in injecting drug users (IDUs), a group at significant risk for HIV infection. Moreover, both HIV infection and depression have been shown to adversely effect neurocognitive abilities. Understanding the effects of depression and HIV infection on the neurocognitive functioning of drug users is essen... | ['Adolescent', 'Adult', 'Cognition', 'Depressive Disorder', 'Diagnosis, Dual (Psychiatry)', 'Ethnic Groups', 'Factor Analysis, Statistical', 'Female', 'Florida', 'HIV Seronegativity', 'HIV Seropositivity', 'Humans', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Sex Characteristics', 'Socioeconomic Factors', 'Subs... | 16,048,441 | [['M01.060.057'], ['M01.060.116'], ['F02.463.188'], ['F03.600.300'], ['E01.190'], ['M01.686.754', 'N01.224.317'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['Z01.107.567.875.750.350'], ['G12.400'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.40... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Trans Tasman Radiation Oncology Group: Development of the Assessment of New Radiation Oncology Technology and Treatments (ANROTAT) Framework. | INTRODUCTION: The study aim was to develop a generic framework to derive the parameters to populate health-economic models for the rapid evaluation of new techniques and technologies in radiation oncology.METHODS: A draft framework was developed through horizon scanning for relevant technologies, literature review to i... | ['Biomedical Research', 'Biotechnology', 'Models, Organizational', 'Radiation Oncology', 'Radiotherapy, Computer-Assisted', 'Tasmania'] | 25,345,713 | [['H01.770.644.145'], ['H01.158.550', 'J01.897.120'], ['E05.599.670', 'N04.452.534'], ['H02.403.429.515.500', 'H02.403.740.650'], ['E02.815.635', 'L01.313.500.750.100.710.600'], ['Z01.639.100.984', 'Z01.678.100.373.984']] | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Determination of co-expression of activation antigens on proliferating CD4+, CD4+ CD8+ and CD8+ lymphocyte subsets by dual parameter flow cytometry. | The incidence of activation markers on proliferating CD4+, CD4+ CD8+ and CD8+ lymphocyte subsets was determined in a single laser Epics-C fluorescence-activated cell sorter system, using a series of double staining combinations. Experiments were performed after 3 days of culture with PHA on cell fractions enriched for ... | ['Adult', 'Antigens, Differentiation, T-Lymphocyte', 'Antigens, Neoplasm', 'Antigens, Surface', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'HLA-DR Antigens', 'Humans', 'Lymphocyte Activation', 'Lymphocytes', 'Middle Aged', 'Neprilysin'] | 2,950,175 | [['M01.060.116'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D23.050.285'], ['D23.050.301'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Physical and genetic mapping of human chromosome 3 loci containing microsatellite repeats. | One hundred and six microsatellite repeat-containing loci, including 59 CA-containing repeats from the CEPH/Genethon collection, were regionally assigned on human chromosome 3 using a somatic cell hybrid mapping panel, diving the chromosome into 14 intervals. The others were dinucleotide and tetranucleotide repeat-cont... | ['Base Sequence', 'Chromosome Mapping', 'Chromosomes, Human, Pair 3', 'DNA Primers', 'DNA, Satellite', 'Humans', 'Lymphocytes', 'Male', 'Molecular Sequence Data', 'Oligonucleotide Probes', 'Polymerase Chain Reaction', 'Repetitive Sequences, Nucleic Acid'] | 7,834,219 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['A11.284.187.520.300.235.250', 'G05.360.162.520.300.235.250'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Accidental CO poisoning by operating a charcoal grill]. | In the hut of a garden plot a male body of at first unknown identity was found. Although a natural death was assumed, autopsy was ordered by the court because of the unclear identity. On autopsy bright red post-mortem lividity was found; an assay of the blood showed 55% CO-Hb. A second inspection of the place, where th... | ['Accidents', 'Carbon Monoxide Poisoning', 'Cause of Death', 'Charcoal', 'Cooking', 'Humans', 'Male', 'Middle Aged', 'Postmortem Changes'] | 8,687,276 | [['N06.850.135'], ['C25.723.455.245'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['D01.268.150.150'], ['J01.576.423.200.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.260.224.617']] | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Synthesis and evaluation of thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. | A number of 2'- and 3'-modified thymidine 5'-O-monophosphate analogues were synthesized as potential leads for new anti-mycobacterial drugs. Evaluation of their affinity for Mycobacterium tuberculosis thymidine monophosphate kinase showed that a 2'-halogeno substituent and a 3'-azido function are the most favorable lea... | ['Antitubercular Agents', 'Crystallography, X-Ray', 'Enzyme Inhibitors', 'Kinetics', 'Models, Molecular', 'Mycobacterium tuberculosis', 'Nucleoside-Phosphate Kinase', 'Thymidine Monophosphate'] | 12,217,356 | [['D27.505.954.122.085.255'], ['E05.196.309.742.225'], ['D27.505.519.389'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['D08.811.913.696.650.575'], ['D03.383.742.686.706.788', 'D13.695.201.789.788', 'D13.695.740.706.788']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways. | To examine the role of clathrin-dependent insulin receptor internalization in insulin-stimulated signal transduction events, we expressed a dominant-interfering mutant of dynamin (K44A/dynamin) by using a recombinant adenovirus in the H4IIE hepatoma and 3T3L1 adipocyte cell lines. Expression of K44A/dynamin inhibited e... | ['3T3 Cells', 'Adenoviridae', 'Animals', 'Clathrin', 'Dynamins', 'Endocytosis', 'Enzyme Activation', 'GTP Phosphohydrolases', 'Genetic Vectors', 'Glycogen', 'Insulin Receptor Substrate Proteins', 'Lipid Metabolism', 'Mice', 'Peptide Fragments', 'Phosphatidylinositol 3-Kinases', 'Phosphoproteins', 'Phosphorylation', 'Pr... | 9,632,770 | [['A11.251.210.100', 'A11.329.228.100'], ['B04.280.030'], ['B01.050'], ['D12.776.543.990.200'], ['D08.811.277.040.330.200', 'D12.776.220.600.450.200', 'D12.776.543.990.400'], ['G04.417'], ['G02.111.263', 'G03.328'], ['D08.811.277.040.330'], ['G05.360.337'], ['D05.750.078.562.388', 'D09.698.365.388'], ['D12.644.360.024.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment of the urgency and deferability of transfusion to inform emergency blood planning and triage: the Bloodhound prospective audit of red blood cell use. | BACKGROUND: Careful planning is essential to ensure blood availability during shortages. Triaging supply is one proposed strategy; however, few data concerning the urgency of transfusion are available to inform planning. This study sought to determine the proportion of red blood cells (RBCs) used for clinically urgent ... | ['Blood Transfusion', 'Emergencies', 'Erythrocyte Transfusion', 'Humans', 'Triage'] | 19,624,492 | [['E02.095.135'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['E02.095.135.140.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.297.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in rats. | Coxsackievirus B3 (CVB3) is a major pathogen for acute and chronic viral myocarditis. The aim of this study was to investigate the antiviral effects of sophoridine, an alkaloid extracted from Chinese medicinal herb, Sophora flavescens, against CVB3, and the underlying pharmacokinetics. First, we determined the antivira... | ['Alkaloids', 'Animals', 'Antiviral Agents', 'Cells, Cultured', 'Chromatography, High Pressure Liquid', 'Coxsackievirus Infections', 'Cytokines', 'Disease Models, Animal', 'Drugs, Chinese Herbal', 'Enterovirus B, Human', 'Longevity', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Myocarditis', 'Myocytes, Cardiac', 'Quinolizin... | 16,309,710 | [['D03.132'], ['B01.050'], ['D27.505.954.122.388'], ['A11.251'], ['E05.196.181.400.300'], ['C01.925.782.687.359.213'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D20.215.784.500.350', 'D26.335'], ['B04.820.578.750.284.182'], ['G07.345.124.519', 'G07.540'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Energetics of best performances in middle-distance running. | Oxygen consumption (VO2) and blood lactate concentration were determined during constant-speed track running on 16 runners of intermediate level competing in middle distances (0.8-5.0 km). The energy cost of track running per unit distance (Cr) was then obtained from the ratio of steady-state VO2, corrected for lactate... | ['Adolescent', 'Adult', 'Aerobiosis', 'Anaerobiosis', 'Energy Metabolism', 'Female', 'Humans', 'Lactates', 'Male', 'Oxygen Consumption', 'Respiratory Function Tests', 'Running'] | 8,335,562 | [['M01.060.057'], ['M01.060.116'], ['G02.111.017', 'G03.049'], ['G02.111.062', 'G03.078'], ['G03.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459'], ['G03.680'], ['E01.370.386.700'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Morphometric definition and grading of gastric intestinal metaplasia. | Type I and type III intestinal metaplasia in gastric mucosa have been examined using morphometric methods. Tissue (volume per cent gland, lumen, epithelium, goblet cell vacuoles) and nuclear parameters (area, with related standard deviation, and form factors) were used as indicators of gland crowding, nuclear-cytoplasm... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cell Nucleus', 'Epithelium', 'Exocrine Glands', 'Female', 'Gastric Mucosa', 'Humans', 'Male', 'Metaplasia', 'Middle Aged', 'Mucins', 'Mucus', 'Sialomucins', 'Stomach', 'Vacuoles'] | 2,391,583 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A10.272'], ['A10.336'], ['A03.556.875.875.440', 'A10.615.550.291'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.589'], ['M01.060.116.630'], ['D12.776.395.560.631'], ['A12.200.503'], ['D12... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immobilization of collagen peptide on dialdehyde bacterial cellulose nanofibers via covalent bonds for tissue engineering and regeneration. | Bacterial cellulose (BC) is an alternative nanostructured biomaterial to be utilized for a wide range of biomedical applications. Because of its low bioactivity, which restricted its practical application, collagen and collagen hydrolysate were usually composited into BC. It is necessary to develop a new method to gene... | ['Biocompatible Materials', 'Cellulose', 'Collagen', 'Immobilized Proteins', 'Nanofibers', 'Tissue Engineering'] | 26,229,466 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D12.776.463'], ['J01.637.512.300'], ['E05.481.500.311.500', 'J01.293.069.249.500']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Constant-pattern design method for the separation of ternary mixtures of rare earth elements using ligand-assisted displacement chromatography. | A constant-pattern design method for separating ternary mixtures using ligand-assisted displacement chromatography was developed for non-ideal systems. The general correlation for the minimum column length required to achieve the constant-pattern state for binary separations from our previous study was extended to tern... | ['Chemistry Techniques, Analytical', 'Chromatography', 'Ligands', 'Metals, Rare Earth', 'Molecular Weight'] | 30,424,966 | [['E05.196'], ['E05.196.181'], ['D27.720.470.480'], ['D01.268.558', 'D01.552.550'], ['G02.494']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DBM induced ectopic bone formation in the rat: the importance of surface area. | Demineralized bone matrix (DBM) has been shown to induce ectopic endochondral bone formation, when intramuscularly implanted in rats. In earlier studies we have found a variation in bone formation capacity of this DBM. This might be due to the properties of the DBM itself, but the use of DBM blocks could be of influenc... | ['Animals', 'Bone Demineralization Technique', 'Bone Matrix', 'Bone Substitutes', 'Bone and Bones', 'Male', 'Materials Testing', 'Osteogenesis', 'Rats', 'Rats, Wistar', 'Surface Properties'] | 15,744,603 | [['B01.050'], ['E05.118'], ['A10.165.265.166'], ['D25.130.325', 'J01.637.051.130.325'], ['A02.835.232', 'A10.165.265'], ['E05.570'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['G02.860']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Prediction of wine foaming. | A procedure for estimating the foam properties of sparkling base wines without specifically measuring foam was developed. This method was based on mathematical equations established between the usual parameters of wine quality control (independent variables of the equations) and the wine foam parameters [foamability (H... | ['Food Handling', 'Quality Control', 'Regression Analysis', 'Surface Tension', 'Wine'] | 10,552,716 | [['J01.576.423.200'], ['J01.897.608'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['G02.860.816'], ['G07.203.100.100.900', 'G07.203.200.887', 'J02.200.100.900', 'J02.350.887']] | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Abolished relationship between pancreatic HCO-3 secretion and arterial pH during carbonic anhydrase inhibition. | After acetazolamide administration, CO2 hydration in pancreatic cells would be slow and might become a rate-limiting factor to pancreatic HCO-3 secretion. Correspondingly, pancreatic HCO-3 secretion-normally pH dependent-would become slow and pH-independent. However, acetazolamide would not be expected to interfere wit... | ['Acetazolamide', 'Animals', 'Bicarbonates', 'Carbonic Anhydrase Inhibitors', 'Hydrogen-Ion Concentration', 'Infusions, Parenteral', 'Pancreas', 'Pancreatic Juice', 'Swine'] | 7,136,751 | [['D02.886.675.867.060', 'D03.383.129.708.867.060'], ['B01.050'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['D27.505.519.389.200'], ['G02.300'], ['E02.319.267.510'], ['A03.734'], ['A12.200.567'], ['B01.050.150.900.649.313.500.880']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Auditory seizures in autoimmune epilepsy: a case with anti-thyroid antibodies. | In its classic presentation, Hashimoto's encephalopathy is an acute-subacute complex neuropsychiatric syndrome with cognitive impairment, hallucinations, myoclonus, tremor or ataxia, associated with elevated anti-thyroid antibodies. Corticoids and immunotherapy are dramatically effective. However, in some cases, not al... | ['Autoantibodies', 'Drug Resistant Epilepsy', 'Encephalitis', 'Hallucinations', 'Hashimoto Disease', 'Humans', 'Male', 'Middle Aged', 'Status Epilepticus'] | 28,287,071 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['C10.228.140.490.125'], ['C10.228.140.430'], ['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['C19.874.871.102.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.597.74... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fenbendazole treatment without environmental decontamination eradicates Syphacia muris from all rats in a large, complex research institution. | Syphacia muris parasitism was eliminated from rats and voles by feeding fenbendazole-medicated chow (150 ppm) for five 7-day periods; treatment periods were separated by 7-day periods of feeding non-medicated chow, yielding atotal treatment course of 9 weeks. No other manipulations to facilitate eradication, including ... | ['Anal Canal', 'Animal Feed', 'Animals', 'Animals, Laboratory', 'Antinematodal Agents', 'Arvicolinae', 'Cricetinae', 'Decontamination', 'Enterobiasis', 'Enterobius', 'Fenbendazole', 'Housing, Animal', 'Parasite Egg Count', 'Rats', 'Rodent Diseases'] | 11,178,318 | [['A03.556.124.526.070', 'A03.556.249.249.070'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.050.199'], ['D27.505.954.122.250.075.080'], ['B01.050.150.900.649.313.992.635.075'], ['B01.050.150.900.649.313.992.635.075.250'], ['N06.850.780.325'], ['C01.610.335.508.700.550.550.375'], ['B01.050.500.50... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of prostacyclin and prostaglandin E2 on the secretion of pancreatic juice in the dog. | 1. Effects of prostacyclin (PGI2) and prostaglandin E2 (PGE2) on the secretion of pancreatic juice were investigated in preparations of the blood-perfused canine pancreas. 2. PGI2 did not affect the basal or secretin-induced pancreatic secretion. However, PGE2 caused a dose-related inhibition of the secretin-induced se... | ['Animals', 'Dinoprostone', 'Dogs', 'Epoprostenol', 'Female', 'Male', 'Pancreas', 'Pancreatic Juice', 'Prostaglandins', 'Prostaglandins E', 'Secretin'] | 6,754,182 | [['B01.050'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['A03.734'], ['A12.200.567'], ['D10.251.355.255.550', 'D23.469.050.175.725'], ['D10.251.355.255.550.250', 'D23.469.050.175.725.250'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Filtration to reduce paediatric dose for a linear slot-scanning digital X-ray machine. | This paper describes modelling, application and validation of a filtration technique for a linear slot-scanning digital X-ray system to reduce radiation dose to paediatric patients while preserving diagnostic image quality. A dose prediction model was implemented, which calculates patient entrance doses using variable ... | ['Aluminum', 'Cadaver', 'Female', 'Filtration', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Monte Carlo Method', 'Phantoms, Imaging', 'Radiation Dosage', 'Radiation Injuries', 'Radiographic Image Enhancement', 'Whole Body Imaging', 'Whole-Body Counting', 'X-Rays'] | 25,433,049 | [['D01.268.557.050', 'D01.552.547.050'], ['C23.550.260.224'], ['E05.196.454', 'G01.280', 'G02.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['E07.671'], ['E05.799.513', 'G01.750.740', 'N... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Barriers associated with the treatment of hepatitis C virus infection among illicit drug users. | BACKGROUND: Illicit drug users account for the majority of cases of HCV infection in the developed world, but few have received treatment.METHODS: We evaluated barriers to initiating HCV treatment -- including general treatment willingness -- and factors associated with these among HCV infected illicit drug users. Part... | ['Adult', 'Female', 'HIV Seropositivity', 'Health Behavior', 'Health Services Accessibility', 'Health Status', 'Hepatitis C', 'Heroin Dependence', 'Humans', 'Illicit Drugs', 'Male', 'Mental Health Services', 'Motivation', 'Urban Population'] | 17,997,050 | [['M01.060.116'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.400.500', 'C01.925.813.400.500', 'C20.673.480.500'], ['F01.145.488'], ['N04.590.374.350', 'N05.300.430'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['C01.221.250.750', 'C01.925.440.440', 'C01.92... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Deformation mechanism and mechanical properties of a thermomechanically processed â Ti-28Nb-35.4Zr alloy. | The effects of thermomechanical treatment on the microstructure and mechanical properties of a newly developed â titanium alloy, i.e., Ti-28Nb-35.4Zr (wt%, hereafter denoted Ti-Nb-Zr) were investigated. The as-cast Ti-Nb-Zr alloy was subjected to solution treatment at 890°C for 1h, after which its thickness was reduced... | ['Alloys', 'Elastic Modulus', 'Hardness', 'Materials Testing', 'Mechanical Phenomena', 'Niobium', 'Temperature', 'Tensile Strength'] | 29,175,491 | [['D01.552.033', 'D25.058', 'J01.637.051.058'], ['G01.374.590.605'], ['G01.374.647'], ['E05.570'], ['G01.374'], ['D01.268.556.615', 'D01.268.956.687', 'D01.552.544.615'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G01.374.850']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Energy metabolism of the peritoneal membrane in silica-induced peritonitis. A biochemical and enzyme histochemical study. | Oxygen and glucose consumption and lactate production of the peritoneal membrane and intra-abdominal adhesions were measured in rats after a single intra-peritoneal colloidal silica injection. Enzyme histochemical studies were made of lactate dehydrogenase, succinate dehydrogenase, NADH2-diaphorase, NADPH2-diaphorase, ... | ['Animals', 'Energy Metabolism', 'Glucose', 'Lactates', 'Male', 'Oxygen Consumption', 'Peritoneum', 'Peritonitis', 'Pyruvates', 'Rats', 'Silicon Dioxide'] | 6,258,364 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dispersion of linear and nonlinear optical susceptibilities and the hyperpolarizability of 3-methyl-4-phenyl-5-(2-pyridyl)-1,2,4-triazole. | As a starting point for our calculation of 3-methyl-4-phenyl-5-(2-pyridyl)-1,2,4-triazole we used the XRD data obtained by C. Liu, Z. Wang, H. Xiao, Y. Lan, X. Li, S. Wang, Jie Tang, Z. Chen, J. Chem. Crystallogr., 2009 39 881. The structure was optimized by minimization of the forces acting on the atoms keeping the la... | ['Electron Transport', 'Linear Models', 'Models, Molecular', 'Molecular Conformation', 'Nonlinear Dynamics', 'Optical Phenomena', 'Pyridines', 'Quantum Theory', 'Triazoles'] | 21,165,515 | [['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E05.599.595'], ['G02.111.570.820'], ['E05.599.850', 'H01.548.675'], ['G01.590'], ['D03.383.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Molecular diversity assessment of arctic and boreal Agaricus taxa. | We provide a phylogenetic diversity assessment study in genus Agaricus as part of our ongoing work to saturate ITS and LSU rDNA sequence diversity of soil-dwelling fungi in Alaska. Pairwise sequence similarity-based groupings and statistical parsimony analyses were applied to delimit operational taxonomic unit (OTU) an... | ['Agaricus', 'Alaska', 'Arctic Regions', 'DNA, Fungal', 'DNA, Ribosomal', 'DNA, Ribosomal Spacer', 'Genetic Variation', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal'] | 18,833,751 | [['B01.300.179.100.105'], ['Z01.107.567.875.580.100'], ['Z01.208'], ['D13.444.308.300'], ['D13.444.308.475'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['G05.365'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686']] | ['Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Abundance and transferability of antibiotic resistance as related to the fate of sulfadiazine in maize rhizosphere and bulk soil. | Veterinary antibiotics entering agricultural land with manure pose the risk of spreading antibiotic resistance. The fate of sulfadiazine (SDZ) introduced via manure and its effect on resistance gene levels in the rhizosphere were compared with that in bulk soil. Maize plants were grown for 9 weeks in soil fertilized wi... | ['Animals', 'Anti-Bacterial Agents', 'Bacterial Proteins', 'Carrier Proteins', 'DNA, Bacterial', 'Drug Resistance, Microbial', 'Escherichia coli', 'Escherichia coli Proteins', 'Fertilizers', 'Genes, Bacterial', 'Manure', 'Plasmids', 'Rhizosphere', 'Soil', 'Soil Microbiology', 'Sulfadiazine', 'Swine', 'Zea mays'] | 22,809,094 | [['B01.050'], ['D27.505.954.122.085'], ['D12.776.097'], ['D12.776.157'], ['D13.444.308.212'], ['G06.225', 'G07.690.773.984.269'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D27.720.031.400'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['D20... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Neuregulin-Dependent Regulation of Fast-Spiking Interneuron Excitability Controls the Timing of the Critical Period. | Maturation of excitatory drive onto fast-spiking interneurons (FS INs) in the visual cortex has been implicated in the control of the timing of the critical period for ocular dominance plasticity. However, the mechanisms that regulate the strength of these synapses over cortical development are not understood. Here we ... | ['Amblyopia', 'Animals', 'Critical Period, Psychological', 'Dominance, Ocular', 'Female', 'Interneurons', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Neuregulin-1', 'Neuronal Plasticity', 'Receptor, ErbB-4', 'Recovery of Function', 'Synapses', 'Vision, Monocular', 'Visual Cortex'] | 27,707,966 | [['C10.228.140.055', 'C10.597.751.941.073', 'C11.966.073', 'C23.888.592.763.941.073'], ['B01.050'], ['F02.463.425.209'], ['G11.561.225.425.500', 'G14.264'], ['A08.675.358', 'A11.671.358'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['... | ['Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The benzodiazepine receptor ligand, methyl beta-carboline-3-carboxylate, is both sedative and proconvulsant in chicks. | Certain pharmacological properties of methyl beta-carboline-3-carboxylate (beta-CCM), a benzodiazepine receptor ligand, have been investigated in chicks. Although beta-CCM has been established previously as an "inverse agonist" of benzodiazepine receptors in rodents, having effects opposite to those of benzodiazepines ... | ['Animals', 'Benzodiazepinones', 'Carbolines', 'Chickens', 'Convulsants', 'Flumazenil', 'Hypnotics and Sedatives', 'Receptors, GABA-A', 'Seizures'] | 3,018,410 | [['B01.050'], ['D03.633.100.079.080.070'], ['D03.383.725.150', 'D03.633.100.473.155', 'D03.633.300.154'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D27.505.696.282.224', 'D27.505.954.427.220.224'], ['D03.633.100.079.080.070.305'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['D12.776.157... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of ionization modifiers on the simultaneous analysis of all classes of phospholipids by nanoflow liquid chromatography/tandem mass spectrometry in negative ion mode. | The effect of ionization modifiers added to the mobile phase of nanoflow liquid chromatography-tandem mass spectrometry (nLC-ESI-MS³) on the simultaneous analysis of all phospholipid (PL) classes in negative ion mode has been investigated. While MS analysis of most PL classes is carried out in negative ion mode, analys... | ['Adult', 'Ammonium Hydroxide', 'Chromatography, Liquid', 'Computer Simulation', 'Humans', 'Hydroxides', 'Male', 'Nanotechnology', 'Phospholipids', 'Tandem Mass Spectrometry'] | 22,503,929 | [['M01.060.116'], ['D01.045.250.225', 'D01.248.497.158.459.113', 'D01.625.062.311'], ['E05.196.181.400'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.045.250', 'D01.248.497.158.459'], ['H01.603', 'J01.897.520.600'], ['D10.570.755'], ['E05.196.566.880']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
Comparison of the dose-response effects of morphine on brain amines, analgesia and activity in mice. | 1. Noradrenaline, dopamine, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid concentrations in the mouse brain were measured 30 min after subcutaneous injection of doses of morphine ranging from 0.1 to 100 mg/kg: motor activity was also measured.2. The noradrenaline concentration in the mouse brain was reduced by mod... | ['Amines', 'Analgesia', 'Animals', 'Brain', 'Brain Chemistry', 'Dopamine', 'Female', 'Hydroxyindoleacetic Acid', 'Injections, Subcutaneous', 'Male', 'Mice', 'Morphine', 'Motor Activity', 'Norepinephrine', 'Serotonin'] | 5,048,647 | [['D02.092'], ['E03.091'], ['B01.050'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ['E02.319.267.530.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.132.577.249.562.571', 'D03.6... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Scintigraphic evaluation of gastric emptying in obese patients submitted to sleeve gastrectomy compared to normal subjects. | BACKGROUND: Sleeve gastrectomy (SG) has been accepted as an option for surgical treatment for obesity. This operation could be associated with motor gastric dysfunction and abnormal gastric emptying. The purpose of this prospective study is to present the results of gastric emptying to liquids and solids using scintigr... | ['Adult', 'Beverages', 'Body Mass Index', 'Case-Control Studies', 'Esophageal Motility Disorders', 'Female', 'Follow-Up Studies', 'Food', 'Gastrectomy', 'Gastric Emptying', 'Humans', 'Kinetics', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Prospective Studies', 'Radionuclide Imaging', 'Treatment Outcome', 'Weight Loss'] | 19,714,384 | [['M01.060.116'], ['G07.203.100', 'J02.200'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C06.405.117.119.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
First examples of metal-organic frameworks with the novel 3,3'-(1,2,4,5-tetrazine-3,6-diyl)dibenzoic spacer. Luminescence and adsorption properties. | We report the synthesis of a novel ligand, 3,3'-(1,2,4,5-tetrazine-3,6-diyl)dibenzoic acid (1). In this fragment, we have introduced two carboxylate groups with the aim of using this ligand as a linker to construct three-dimensional metal-organic frameworks (MOFs). We have been successful in the formation of zinc (2) a... | ['Adsorption', 'Animals', 'Benzoates', 'Cell Survival', 'Cells, Cultured', 'Crystallography, X-Ray', 'Heterocyclic Compounds', 'Humans', 'Lanthanum', 'Luminescence', 'Organometallic Compounds', 'Zinc'] | 23,286,441 | [['G01.030', 'G02.020'], ['B01.050'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['G04.346'], ['A11.251'], ['E05.196.309.742.225'], ['D03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.558.362.500', 'D01.552.550.399.500'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.75... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Influence of coordination compounds of germanium (IV) and stannum (IV) on activity of some microbial enzymes with glycolytic and proteolytic action]. | Influence of coordinative compounds of germanium (IV) and stanum (IV) (complexes of germanium (IV) with nicotinamide (Nad) [GeCl2(Nad)4]Cl2 (1) and complexes of stanum (IV) with 2-hydroxybenzoilhydrazone 4-dimetylaminobenzaldehide (2-OH-HBdb) [SnCl4(2-OH-Bdb-H)] (2), 3-hydroxy-2-naphtoilhydrazone 2-hydroxynaphtaldehide... | ['Anti-Infective Agents', 'Aspergillus flavus', 'Bacillus thuringiensis', 'Bacterial Proteins', 'Benzaldehydes', 'Coordination Complexes', 'Cryptococcus', 'Eupenicillium', 'Fungal Proteins', 'Germanium', 'Glycoside Hydrolases', 'Hydrazones', 'Microbial Sensitivity Tests', 'NAD', 'Organotin Compounds', 'Peptide Hydrolas... | 25,639,038 | [['D27.505.954.122'], ['B01.300.381.081.170'], ['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['D12.776.097'], ['D02.047.222'], ['D01.234', 'D02.257'], ['B01.300.381.258', 'B01.300.930.316'], ['B01.300.107.320.215'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis. | Mutations of the human cationic trypsinogen gene (PRSS1) are frequently found in association with hereditary pancreatitis. The most frequent variants p.N29I and p.R122H are recognized as disease-causing mutations. Three pseudogene paralogs in the human trypsinogen family, including trypsinogen 6 (PRSS3P2), carry sequen... | ['Alleles', 'Cell Line', 'Child', 'Female', 'Gene Conversion', 'Humans', 'Male', 'Pancreatitis, Chronic', 'Pseudogenes', 'Trypsin', 'Young Adult'] | 25,546,417 | [['G05.360.340.024.340.030'], ['A11.251.210'], ['M01.060.406'], ['G05.728.615.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.689.750.830'], ['G05.360.340.024.340.700'], ['D08.811.277.656.300.760.895', 'D08.811.277.656.959.350.895'], ['M01.060.116.815']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Self-reported barriers to pediatric surgical care in Guatemala. | Access to pediatric surgical care is limited in low- and middle-income countries. Barriers must be identified before improvements can be made. This pilot study aimed to identify self-reported barriers to pediatric surgical care in Guatemala. We surveyed 78 families of Guatemalan children with surgical conditions who we... | ['Adolescent', 'Child', 'Child, Preschool', 'Delivery of Health Care', 'Female', 'Follow-Up Studies', 'General Surgery', 'Guatemala', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Pediatrics', 'Pilot Projects', 'Quality Assurance, Health Care', 'Retrospective Studies', 'Self Report', 'Surveys and Questionnaires'] | 24,069,982 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['N04.590.374', 'N05.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['H02.403.810.300'], ['Z01.107.169.454'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['H02.403.670'],... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
The interaction of prostaglandins with high-density lipoproteins: a non-equilibrium model of ligand-receptor interaction. | Using high-density lipoproteins (HDL) labeled with a fluorescent phospholipid probe (an anthrylvinyl-labeled analogue of sphingomyelin) it was found that low amounts (10(-12) M) of the prostaglandins E1 and F2 alpha induced different structural changes of the HDL surface, whereas prostaglandin E2 had no effect. The eff... | ['Alprostadil', 'Apolipoproteins A', 'Dinoprost', 'Energy Transfer', 'Fluorescence Polarization', 'Fluorescent Dyes', 'Humans', 'Lipoproteins, HDL', 'Prostaglandins F', 'Spectrometry, Fluorescence', 'Sphingomyelins'] | 3,477,290 | [['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['D10.532.091.200', 'D12.776.070.400.200', 'D12.776.521.120.200'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['E05.196.712.516.600.390'], ['D27.720.233.348', 'D27.720.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biomechanical study of the pitching elbow. | Medial-tension injuries of the pitching elbow are well recognized. One contributing factor is the extreme valgus which has been noted to occur during the acceleration phase of throwing. It is hypothesized that breaking pitches generate higher medial loading because of the pronation and supination required to impart spi... | ['Baseball', 'Biomechanical Phenomena', 'Elbow', 'Electromyography', 'Forearm', 'Hand', 'Humans', 'Movement', 'Sports'] | 528,089 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Shock absorbing ability in healthy and damaged cartilage-bone under high-rate compression. | Articular cartilage is a soft tissue that distributes the loads in joints and transfers the compressive load to the underlying bone. At high rate and magnitudes of mechanical loading, cartilage and subchondral bone together are susceptible to damage. In addition, any disruption to the cartilage's structure, caused by i... | ['Animals', 'Biomechanical Phenomena', 'Cartilage, Articular', 'Cattle', 'Compressive Strength', 'Materials Testing', 'Weight-Bearing'] | 30,445,365 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.500.380.271'], ['G01.374.180'], ['E05.570'], ['G01.374.965']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polystyrene scaffolds based on microfibers as a bone substitute; development and in vitro study. | UNLABELLED: We created non-resorbable porous scaffolds of polystyrene by electrospinning usable as a bone grafting material. Aligned and random fibers were prepared with a diameter ranging from 1 to 4.5ìm. Influence of microfiber diameter and alignment were determined by culturing MC3T3 osteoblast-like cells and evalua... | ['Alkaline Phosphatase', 'Animals', 'Antigens, Differentiation', 'Bone Substitutes', 'Cell Adhesion', 'Cell Line', 'Cell Proliferation', 'Mice', 'Osteoblasts', 'Polystyrenes', 'Tissue Scaffolds'] | 26,518,105 | [['D08.811.277.352.650.035'], ['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['D25.130.325', 'J01.637.051.130.325'], ['G04.022'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.329.629'], ['D02.455.426.559.389.150.750.800.830', 'D05.750.716.579', 'D25.720.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Wilson's disease, a reversible dementia: case report. | A case of advanced Wilson's disease with clear dementing features is presented. Neuropsychological evaluation before treatment revealed intellectual deterioration particularly in memory and performance tasks. The patient was treated with Penicillamine, a copper-chelating agent, for 7 months, with notable improvement in... | ['Adult', 'Dementia', 'Female', 'Hepatolenticular Degeneration', 'Humans', 'Neuropsychological Tests', 'Penicillamine', 'Tomography, X-Ray Computed'] | 3,597,731 | [['M01.060.116'], ['C10.228.140.380', 'F03.615.400'], ['C06.552.413', 'C10.228.140.079.493', 'C10.228.140.163.100.360', 'C10.228.662.400', 'C10.574.500.487', 'C16.320.400.361', 'C16.320.565.189.360', 'C16.320.565.618.403', 'C18.452.132.100.360', 'C18.452.648.189.360', 'C18.452.648.618.403'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The responses of afferent fibres from the glabrous skin of the hand during voluntary finger movements in man. | 1. Afferent activity of 111 single units from the glabrous skin area was recorded percutaneously in the median nerve of human subjects, using tungsten electrodes. 2. The majority of the units (103) were classified as low-threshold mechano-sensitive units belonging to one of the four categories previously described: rap... | ['Adult', 'Finger Joint', 'Fingers', 'Hand', 'Humans', 'Mechanoreceptors', 'Movement', 'Neurons, Afferent', 'Skin'] | 480,210 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Conceptual and methodologic bases of the National Health Survey II, Mexico, 1994. Conceptual Coordinating and Designing Group of ENSA-II]. | The conceptual and methodological basis of the National Health Survey II (NHS-II) are described and recent advances in multidisciplinary public health research in Mexico, both conceptual and methodological, are synthesized. The design of the NHS-II concentrated on the study of the access, quality of care and health att... | ['Age Distribution', 'Health Care Costs', 'Health Care Surveys', 'Health Services Accessibility', 'Humans', 'Mexico', 'Quality of Health Care'] | 9,567,660 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['N03.219.151.400', 'N05.300.375'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.589'], ['N04.761... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Patients younger than 40 years with gastric carcinoma: Helicobacter pylori genotype and associated gastritis phenotype. | BACKGROUND: In the general population, Helicobacter pylori (H. pylori), particularly the cagA positive strain, has been associated with intestinal-type gastric carcinoma. Gastric carcinomas are rarely observed in patients age < or = 40 years. Host-related factors have been thought to be more important than environmenta... | ['Adenocarcinoma', 'Adolescent', 'Adult', 'Amino Acid Sequence', 'DNA, Bacterial', 'Female', 'Gastritis, Atrophic', 'Gene Expression Regulation, Bacterial', 'Gene Expression Regulation, Neoplastic', 'Genotype', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Molecular Sequence Data', 'Recombinant F... | 10,375,095 | [['C04.557.470.200.025'], ['M01.060.057'], ['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D13.444.308.212'], ['C06.405.205.697.394', 'C06.405.748.398.394'], ['G05.308.300'], ['G05.308.370'], ['G05.380'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.3... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Early- and late-onset psoriasis: a cross-sectional clinical and immunocytochemical investigation. | BACKGROUND: There is accumulating evidence that early-onset psoriasis (EOP; presenting at or before 40 years of age) and late-onset psoriasis (LOP; presenting after 40 years of age) are different diseases.OBJECTIVES: We aimed to identify potential clinical and immunocytochemical differences between EOP and LOP.METHODS:... | ['Adolescent', 'Adult', 'Age of Onset', 'Aged', 'CD4-CD8 Ratio', 'Cell Count', 'Cross-Sectional Studies', 'England', 'Female', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Psoriasis', 'Retrospective Studies', 'Young Adult'] | 27,459,949 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['E01.370.225.500.195.107.595.500.150.160', 'E01.370.225.625.107.595.500.150.160', 'E05.200.500.195.107.595.500.150.160', 'E05.200.625.107.595.500.150.160', 'E05.242.195.107.595.500.150.160', 'G04.140.107.595.500.150... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Supratentorial ependymoma: disease control, complications, and functional outcomes after irradiation. | PURPOSE: Ependymoma is less commonly found in the supratentorial brain and has known clinical and molecular features that are unique. Our single-institution series provides valuable information about disease control for supratentorial ependymoma and the complications of supratentorial irradiation in children.METHODS AN... | ['Adolescent', 'Brain Neoplasms', 'Child', 'Child, Preschool', 'Cognition', 'Educational Status', 'Ependymoma', 'Female', 'Hormone Replacement Therapy', 'Humans', 'Infant', 'Intelligence', 'Male', 'Radiotherapy Dosage', 'Radiotherapy, Adjuvant', 'Radiotherapy, Conformal', 'Seizures', 'Supratentorial Neoplasms', 'Treatm... | 23,245,280 | [['M01.060.057'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['M01.060.406.448'], ['F02.463.188'], ['N01.824.196'], ['C04.557.465.625.600.380.290', 'C04.557.470.670.380.290', 'C04.557.580.625.600.380.290'], ['E02.319.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
N-linked oligosaccharides of glycoproteins from Ginkgo biloba pollen, an allergenic pollen. | The pollen of Ginkgo biloba is one of the allergens that cause pollen allergy symptoms. The plant complex type N-glycans bearing beta1-2 xylose and/or alpha1-3 fucose residue(s) linked to glycoallergens have been considered to be critical epitopes in various immune reactions. In this report, the structures of N-glycans... | ['Allergens', 'Carbohydrate Conformation', 'Carbohydrate Sequence', 'Chromatography, High Pressure Liquid', 'Epitopes', 'Ginkgo biloba', 'Glycoproteins', 'Molecular Sequence Data', 'Oligosaccharides', 'Pollen'] | 11,676,012 | [['D23.050.063'], ['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['E05.196.181.400.300'], ['D23.050.550'], ['B01.650.940.800.575.912.125'], ['D09.400.430', 'D12.776.395'], ['L01.453.245.667'], ['D09.698.629'], ['A18.024.249.500.249.500']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
State-specific trends in lung cancer incidence and smoking--United States, 1999-2008. | Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer death in the United States. Most deaths from lung cancer are caused by cigarette smoking and exposure to secondhand smoke. Large variations in lung cancer, smoking behavior, and tobacco control programs and policies have been observed amo... | ['Female', 'Humans', 'Incidence', 'Lung Neoplasms', 'Male', 'Prevalence', 'Public Policy', 'SEER Program', 'Smoking', 'Smoking Cessation', 'Taxes', 'United States'] | 21,918,494 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.98... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
A tale of two bridges: effect of the bloodless bridge on renal function and blood pressure in neonates managed with venoarterial extracorporeal membrane oxygenation. | OBJECTIVE: To investigate if a change in bridge design of the extracorporeal membrane oxygenation (ECMO) circuit had an impact on renal function and blood pressure in neonates requiring venoarterial ECMO support.DESIGN: : Retrospective chart review.SETTING: A tertiary care neonatal intensive care unit and ECMO center.P... | ['Blood Pressure', 'Chi-Square Distribution', 'Extracorporeal Membrane Oxygenation', 'Female', 'Humans', 'Infant, Newborn', 'Intensive Care Units, Neonatal', 'Kidney', 'Kidney Function Tests', 'Male', 'Retrospective Studies'] | 19,741,447 | [['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E02.880.301', 'E04.292.451'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['N02.278.388.493.390.380'], ['A05.810.453'], ['E01.370.390.400'], ['E05.318.37... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 cooperates with enhancer of zeste homolog 2 to promote hepatocellular carcinoma development by modulating the microRNA-22/Snail family transcriptional repressor 1 axis. | Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is an oncogenic long noncoding RNA that has been found to promote carcinogenesis and metastasis in many tumors. However, the underlying role of MALAT1 in the progression and metastasis of hepatocellular carcinoma (HCC) remains unclear. In this study, aberr... | ['Animals', 'Antigens, CD', 'Binding Sites', 'Cadherins', 'Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Disease Progression', 'Enhancer of Zeste Homolog 2 Protein', 'Epithelial-Mesenchymal Transition', 'Female', 'Gene Expression', 'Gene Expression Regulation, Neoplastic', 'Gen... | 32,129,914 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['G02.111.570.120'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Personal method of transhiatal esophageal resection for neoplasm using thoracoscopy]. | A method of the simultaneous with vats is presented. While lifting the oesophagus by hand introduced through widened hiatus the mobilization is performed using VATS. | ['Aged', 'Esophageal Neoplasms', 'Esophagectomy', 'Humans', 'Male', 'Middle Aged', 'Thoracoscopy'] | 9,446,384 | [['M01.060.116.100'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E04.210.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.388.250.840', 'E04.502.250.840', 'E04.928.752']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of chain flexibility on cell adhesion: Semi-flexible model-based analysis of cell adhesion to hydrogels. | Hydrogels have been developed and applied to various biomedical applications due to their biocompatibility. However, understanding of modulation between cells to hydrogel interface is still unclear, and parameters to explain the interaction are not sophisticated enough. In this report, we studied the effect of polymer ... | ['Animals', 'Biocompatible Materials', 'Cell Adhesion', 'Collagen', 'Elastic Modulus', 'Fibrin', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Hydrogels'] | 30,792,420 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['G04.022'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G01.374.590.605'], ['D12.776.124.270'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.280.320.375', 'D26.255.165.320.375']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Conversion of waste produced by the deodorization of palm oil as feedstock for the production of biodiesel using a catalyst prepared from waste material. | The distillate produced by deodorization of palm oil (DDPO) is a waste that corresponds to 4% of the product formed in this process. DDPO is 83% free of fatty acids (FFA), making it a good material for biodiesel production. In this paper, a catalyst prepared from a waste material, Amazon flint kaolin, was used for the ... | ['Biofuels', 'Catalysis', 'Kinetics', 'Odorants', 'Palm Oil', 'Plant Oils', 'Refuse Disposal', 'Temperature'] | 21,704,520 | [['D20.147', 'N06.230.132.644.124'], ['G02.130'], ['G01.374.661', 'G02.111.490'], ['G16.500.275.640', 'N06.230.480'], ['D10.627.700.798', 'D20.215.784.750.728'], ['D10.627.700', 'D20.215.784.750'], ['N06.850.780.200.800.800.700', 'N06.850.860.510.900.600'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.71... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
LncRNA Gm5091 alleviates alcoholic hepatic fibrosis by sponging miR-27b/23b/24 in mice. | The regulatory roles of lncRNAs in the development of alcoholic hepatic fibrosis (AHF) have not been revealed. Here, we found lncRNA Gm5091 was being downregulated in mouse hepatic stellate cells (HSCs) during AHF. Then, Gm5091 was, respectively, overexpressed and knocked down in alcohol-treated primary HSCs. Our resul... | ['Animals', 'Cell Movement', 'Down-Regulation', 'Hepatic Stellate Cells', 'Liver Cirrhosis, Alcoholic', 'Male', 'Mice', 'Mice, Inbred C57BL', 'MicroRNAs', 'RNA, Long Noncoding'] | 29,935,035 | [['B01.050'], ['G04.198', 'G07.568.500.180'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['A11.561'], ['C06.552.630.380', 'C06.552.645.590', 'C23.550.355.412.380', 'C25.775.100.087.645.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.40... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid, phenotypic HIV-1 drug sensitivity assay for protease and reverse transcriptase inhibitors. | BACKGROUND: Development of drug resistance is one of the major reasons for the failure of antiretroviral therapy of HIV-1 infection. Knowing the drug sensitivity-resistance profile of viruses present in a patient prior to treatment or change in treatment could help to optimize therapy.OBJECTIVE: Development of a rapid ... | ['Anti-HIV Agents', 'Cell Line', 'HIV Infections', 'HIV Protease', 'HIV Protease Inhibitors', 'HIV Reverse Transcriptase', 'HIV-1', 'Humans', 'Microbial Sensitivity Tests', 'Phenotype', 'Reverse Transcriptase Inhibitors', 'Time Factors'] | 10,405,894 | [['D27.505.954.122.388.077.088'], ['A11.251.210'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['D08.811.277.656.074.500.340', 'D08.811.277.656.300.048.340', 'D08.811.277.656.979.500', 'D12.776.964.775.375.545.750', 'D12.776.964.900.500.625... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-selective inhibition of mammalian protein kinases by flavinoids in vitro. | In vitro, the flavinoids quercetin, morin, and rutin produced comparable inhibition of protein kinase C prepared from bovine brain, the epidermal growth factor (EGF)-stimulated tyrosine specific protein kinase associated with A431 cell membranes, and the cAMP-stimulated protein kinase activity associated with rat brain... | ['Adenosine Triphosphate', 'Animals', 'Cell Line', 'Electrophoresis, Polyacrylamide Gel', 'Epidermal Growth Factor', 'Flavonoids', 'Phosphoproteins', 'Phosphorylation', 'Protein Kinase C', 'Protein Kinase Inhibitors'] | 3,495,834 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A11.251.210'], ['E05.196.401.402', 'E05.301.300.319'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D12.776.744'], ['G02.111.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A safe, blood-brain barrier permeable triphenylmethane dye inhibits amyloid-â neurotoxicity by generating nontoxic aggregates. | Growing evidence suggests that on-pathway amyloid-â (Aâ) oligomers are primary neurotoxic species and have a direct correlation with the onset of Alzheimer's disease (AD). One promising therapeutic strategy to block AD progression is to reduce the levels of these neurotoxic Aâ species using small molecules. While sever... | ['Amyloid beta-Peptides', 'Benzothiazoles', 'Blood-Brain Barrier', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Fluorescent Dyes', 'Humans', 'Microscopy, Electron, Transmission', 'Nerve Fibers', 'Neuroprotective Agents', 'Oxazines', 'Protein Binding', 'Rosaniline Dyes', 'Thiazoles', 'Trityl Compounds', 'Xanthe... | 22,860,159 | [['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['D03.383.129.708.089', 'D03.633.100.185'], ['A07.035', 'A08.186.211.035'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.580'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reading errors in first- and second-grade readers of a shallow orthography: evidence from Spanish. | BACKGROUND: Studies focusing on reading errors can help to understand how children learn to read and to structure key components of reading instruction. However, no prior studies have examined which letters might be a greater source of difficulty for beginning readers in Spanish.AIMS: First, to examine the pattern of r... | ['Child', 'Discrimination Learning', 'Female', 'Form Perception', 'Humans', 'Learning', 'Male', 'Pattern Recognition, Visual', 'Reading', 'Spain', 'Teaching'] | 16,719,967 | [['M01.060.406'], ['F02.463.425.280'], ['F02.463.593.373', 'F02.463.593.778.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['L01.559.423.557'], ['Z01.542.846'], ['I02.903']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 |
Boswellic acids reduce Th17 differentiation via blockade of IL-1â-mediated IRAK1 signaling. | Interferon-gamma producing CD4(+) T (Th1) cells and IL-17-producing CD4(+) T (Th17) cells are involved in the pathogenesis of several autoimmune diseases including multiple sclerosis. Therefore, the development of treatment strategies controlling the generation and expansion of these effector cells is of high interest.... | ['Adult', 'Blotting, Western', 'CD4-Positive T-Lymphocytes', 'Cell Differentiation', 'Cells, Cultured', 'Cytokines', 'Flow Cytometry', 'Humans', 'Interferon-gamma', 'Interleukin-1 Receptor-Associated Kinases', 'Interleukin-17', 'Interleukin-1beta', 'Phosphorylation', 'STAT3 Transcription Factor', 'Signal Transduction',... | 24,469,975 | [['M01.060.116'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.152'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E01.370.225.500.363... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A reappraisal on the management of lumbosacral plexopathies in gynecological malignancies: where do the physiatrists stand? | Two patients are reported here with gynecological malignancies--an ovarian and a cervical carcinoma--who had suffered from lumbar plexopathies during their follow-up. Their management is discussed with an emphasis on the collaboration of the gynecologists and the rehabilitation physicians. | ['Female', 'Humans', 'Lumbosacral Region', 'Middle Aged', 'Tomography Scanners, X-Ray Computed', 'Uterine Neoplasms'] | 16,174,245 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.176.519'], ['M01.060.116.630'], ['E07.913'], ['C04.588.945.418.948', 'C13.351.500.852.762', 'C13.351.937.418.875']] | ['Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Indomethacin decreases furosemide-induced natriuresis and diuresis on the neonatal kidney. | Indomethacin is used to pharmacologically occlude patent ductus arteriosus in preterm infants. It induces renal untoward effects and furosemide is administered simultaneously to counteract them. The effect of furosemide is blunted by indomethacin. We analyzed comparatively the interactions of furosemide and indomethaci... | ['Animals', 'Animals, Newborn', 'Diuresis', 'Diuretics', 'Drug Antagonism', 'Female', 'Furosemide', 'Glomerular Filtration Rate', 'Indomethacin', 'Kidney', 'Natriuresis', 'Osmosis', 'Rats', 'Rats, Wistar', 'Sodium', 'Urine', 'Water'] | 16,932,901 | [['B01.050'], ['B01.050.050.282'], ['G08.852.179'], ['D27.505.696.560.500'], ['G07.690.773.968.310'], ['D02.065.884.725.300', 'D02.092.146.807.300', 'D02.886.590.700.725.300'], ['E01.370.390.400.300', 'G08.852.357'], ['D03.633.100.473.420'], ['A05.810.453'], ['G08.852.179.557'], ['G01.154.090.750', 'G02.111.655', 'G02.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spectrum of Von Willebrand disease and inherited platelet function disorders amongst Indian bleeders. | Platelet function disorders (PFD) and Von Willebrand disease (VWD) are among the uncommon causes of bleeding in haematological practice. The inherited variety of PFD includes defects in platelet adhesion, aggregation, secretion and platelet procoagulant activities. VWD is classified into three major categories-type 1 a... | ['Adolescent', 'Adult', 'Blood Coagulation Disorders', 'Blood Platelet Disorders', 'Child', 'Child, Preschool', 'Female', 'Humans', 'India', 'Male', 'Middle Aged', 'Prevalence', 'von Willebrand Diseases'] | 17,375,300 | [['M01.060.057'], ['M01.060.116'], ['C15.378.100'], ['C15.378.140'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['C15.37... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[A case of successful use of triple approach in a kidney cancer patient with metastatic lesion to the lung and pleural cavity]. | Metastasis to the lung is the most common place connected with kidney cancer progression. Wherein metastasectomy is accompanied by satisfactory 5- and 10-year survival achieving 49% and 21% respectively. Pleural lesion due to this tumor develops as a part of systemic metastasis and, as a rule, is a consequence of neopl... | ['Aged', 'Antineoplastic Agents', 'Cisplatin', 'Dendritic Cells', 'Drainage', 'Drug Administration Schedule', 'Humans', 'Hyperthermia, Induced', 'Kidney Neoplasms', 'Lung Neoplasms', 'Male', 'Photochemotherapy', 'Pleural Cavity', 'Pleural Neoplasms', 'Thoracotomy', 'Transplantation, Autologous', 'Treatment Outcome'] | 25,816,672 | [['M01.060.116.100'], ['D27.505.954.248'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['E02.309', 'E04.237'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Relationships between the degree of cross-linking of surface immunoglobulin and the associated inositol 1,4,5-trisphosphate and Ca2+ signals in human B cells. | Cross-linking of surface immunoglobulin (Ig) receptors on human B cells leads to the activation of a tyrosine kinase. The activated tyrosine kinase subsequently phosphorylates a number of substrates, including phospholipase C-gamma. This enzyme breaks down phosphoinositol bisphosphate to form two intracellular messenge... | ['B-Lymphocytes', 'Calcium', 'Cations, Divalent', 'Cells, Cultured', 'Chromatography, High Pressure Liquid', 'Cross-Linking Reagents', 'Enzyme Activation', 'Humans', 'Inositol 1,4,5-Trisphosphate', 'Inositol Phosphates', 'Palatine Tonsil', 'Protein-Tyrosine Kinases', 'Receptors, Antigen, B-Cell', 'Signal Transduction',... | 1,599,430 | [['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.248.497.300.333'], ['A11.251'], ['E05.196.181.400.300'], ['D27.720.470.410.210'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.9... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of nucleolin on adriamycin resistance via the regulation of B-cell lymphoma 2 expression in Burkitt's lymphoma cells. | Nucleolin (NCL, C23) is an important nucleocytoplasmic multifunctional protein. Due to its multifaceted profile and high expression in cancer, NCL is considered to be a marker of drug resistance associated with chemotherapy. However, the biochemical mechanisms in which NCL suppresses drug sensitivity in several cancers... | ['Antibiotics, Antineoplastic', 'Apoptosis', 'Burkitt Lymphoma', 'Cell Line, Tumor', 'Doxorubicin', 'Drug Resistance, Neoplasm', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Phosphoproteins', 'Protein Binding', 'Proto-Oncogene Proteins c-bcl-2', 'RNA Stability', 'RNA, Messenger', 'RNA-Binding Proteins', 'Signal... | 31,127,617 | [['D27.505.954.248.106'], ['G04.146.954.035'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seasonal influenza vaccine effectiveness among children, 2010-2012. | BACKGROUND: The annual differences in the seasonal influenza vaccine and the circulating strains make it necessary to assess influenza vaccine effectiveness (VE) yearly. We assessed the effectiveness of the trivalent inactivated influenza vaccine for the 2010-2011 and 2011-2012 influenza seasons among children in Guang... | ['Case-Control Studies', 'Child, Preschool', 'China', 'Female', 'Humans', 'Infant', 'Influenza Vaccines', 'Influenza, Human', 'Male', 'Vaccines, Inactivated'] | 23,981,250 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406.448'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['D20.215.894.830']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
CROI 2017: Advances in Antiretroviral Therapy. | The 2017 Conference on Retroviruses and Opportunistic Infections (CROI) featured exciting preclinical data on investigational antiretroviral agents with good in vitro efficacy and long half-lives. Investigational medications, including bictegravir, demonstrated excellent efficacy and tolerability, as did dual-agent the... | ['Anti-HIV Agents', 'Anti-Retroviral Agents', 'HIV Infections', 'Humans', 'Lamivudine', 'New York City', 'Zika Virus', 'Zika Virus Infection'] | 28,598,790 | [['D27.505.954.122.388.077.088'], ['D27.505.954.122.388.077'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.742.680.245.500.950.500', 'D13.570.230.329.950.500', 'D13.570.230.500.925.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Variation profiles of common surgical procedures. | BACKGROUND: Rates of many surgical procedures vary widely across both large and small geographic regions. Although variation in health care use has long been described, few studies have systematically compared variation profiles across surgical procedures. The goal of this study was to examine current patterns of regio... | ['Aged', 'Aged, 80 and over', 'Humans', 'Medicare', "Practice Patterns, Physicians'", 'Surgical Procedures, Operative', 'United States'] | 9,823,407 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.706.615.696'], ['N04.590.374.577', 'N05.300.625'], ['E04'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Acute pelvic pain syndrome. Diagnostic and therapeutic approach in women]. | Acute pelvic pain is a common syndrome in women and is an emergency. Management requires rapid diagnostic evaluation to enable immediate treatment. Blood tests (beta-HCG assay, etc.), bacteriological studies and pelvic ultrasonography may be required. Gynecological problems are the commonest etiology: ectopic pregnancy... | ['Abortion, Spontaneous', 'Adnexal Diseases', 'Adult', 'Appendicitis', 'Colic', 'Diagnosis, Differential', 'Diverticulitis, Colonic', 'Emergencies', 'Female', 'Genital Diseases, Female', 'Humans', 'Middle Aged', 'Ovarian Cysts', 'Pelvic Inflammatory Disease', 'Pelvic Pain', 'Pregnancy', 'Pregnancy, Ectopic', 'Rupture, ... | 7,817,082 | [['C13.703.039', 'G08.686.784.769.496.125'], ['C13.351.500.056'], ['M01.060.116'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['C16.614.166'], ['E01.171'], ['C06.405.205.282.500.250', 'C06.405.469.158.587.500'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['C13.351.500'], ['B01.050.150.900.64... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of optical isomers of clenbuterol on the relaxant response in rat uterus. | Previous works have shown that the administration of the racemic beta -adrenoceptor agent clenbuterol produces a desensitization of the relaxant response in rat uterus. The aim of this work was to study the effects of the optical isomers of clenbuterol on the relaxant response in rat uterus. The administration of (L)-c... | ['Adrenergic beta-Agonists', 'Animals', 'Clenbuterol', 'Dose-Response Relationship, Drug', 'Female', 'Muscle Relaxation', 'Myometrium', 'Rats', 'Rats, Wistar', 'Receptors, Adrenergic, beta-2', 'Stereoisomerism'] | 11,243,716 | [['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['B01.050'], ['D02.033.100.291.231', 'D02.092.063.291.231'], ['G07.690.773.875', 'G07.690.936.500'], ['G11.427.494.554'], ['A02.633.570.500', 'A05.360.319.679.690', 'A10.690.467.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A rare form of total abnormal pulmonary stenosis return: atresia of the common pulmonary vein]. | One case of atresia of the common pulmonary vein is discussed at the light of the few reports found in the literature. The presence of criteria distinguishing this type of obstacle to pulmonary venous return from the other cases, is of practical diagnostic interest; indeed, its diagnosis leads to surgical intervention,... | ['Child, Preschool', 'Electrocardiography', 'Humans', 'Male', 'Pulmonary Valve Stenosis', 'Pulmonary Veins'] | 931,535 | [['M01.060.406.448'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.484.716', 'C14.280.955.750'], ['A07.015.908.713']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Is radiation indicated in patients with ductal carcinoma in situ and close or positive mastectomy margins? | PURPOSE: Resection margin status is one of the most significant factors for local recurrence in patients with ductal carcinoma in situ (DCIS) treated with breast-conserving surgery with or without radiation. However, its impact on chest wall recurrence in patients treated with mastectomy is unknown. The purpose of this... | ['Adult', 'Aged', 'Aged, 80 and over', 'Axilla', 'Breast Neoplasms', 'Carcinoma in Situ', 'Carcinoma, Ductal, Breast', 'Female', 'Humans', 'Lymph Node Excision', 'Mastectomy', 'Mastectomy, Segmental', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm, Residual', 'Radiotherapy, Adjuvant', 'Thoracic Wall', 'Tumor Bu... | 20,646,871 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A01.378.800.090'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.240'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['E04.466'... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Maternal periodontal status and preterm delivery: a hospital based case-control study. | BACKGROUND AND OBJECTIVE: Recent studies have presented evidence that periodontal disease in pregnant women may be a determining factor for preterm delivery. However, this finding has not been consistently observed. The present investigation was carried out to explore the association between maternal periodontal diseas... | ['Adult', 'Case-Control Studies', 'Female', 'Hospitals', 'Humans', 'Logistic Models', 'Periodontal Index', 'Periodontitis', 'Physical Exertion', 'Pregnancy', 'Premature Birth', 'Prenatal Care', 'Risk Factors', 'Social Class', 'Tobacco Smoke Pollution', 'Young Adult'] | 21,507,002 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Audiovisual matching in speech and nonspeech sounds: a neurodynamical model. | Audiovisual speech perception provides an opportunity to investigate the mechanisms underlying multimodal processing. By using nonspeech stimuli, it is possible to investigate the degree to which audiovisual processing is specific to the speech domain. It has been shown in a match-to-sample design that matching across ... | ['Acoustic Stimulation', 'Computer Simulation', 'Humans', 'Models, Neurological', 'Neural Networks, Computer', 'Nonlinear Dynamics', 'Photic Stimulation', 'Sound', 'Speech', 'Speech Perception', 'Visual Perception'] | 19,302,007 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.642'], ['G17.485', 'L01.224.050.375.605'], ['E05.599.850', 'H01.548.675'], ['E05.723.729'], ['G01.750.770.776'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['F02.463.593.071.87... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Spontaneous mutation rate in clones of Chinese hamster cells differing in UV sensitivity]. | The paper deals with a study of the rate of spontaneous mutations to 6-mercaptopurine resistance in cells of CHR2, CHS2 clones differing in sensitivity to the lethal and mutagenic effects of UV irradiation. An enhanced UV-sensitivity of CHS2 clone was shown earlier to be the result of a disturbance in postreplication D... | ['Animals', 'Cells, Cultured', 'Clone Cells', 'Cricetinae', 'Cricetulus', 'DNA Repair', 'Mercaptopurine', 'Mutation', 'Radiation Tolerance', 'Ultraviolet Rays'] | 6,683,211 | [['B01.050'], ['A11.251'], ['A11.251.353'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['G02.111.222', 'G05.219'], ['D02.886.489.534', 'D03.633.100.759.570'], ['G05.365.590'], ['G04.712', 'G07.738'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891',... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Low-frequency collective chain dynamics in a model biomembrane. | Proton NMR was employed as a probe for the collective hydrocarbon chain dynamics in decylammonium chloride (C10H21NH3Cl), a model biomembrane undergoing an irreversible structural phase transition sequence. Our rotating frame spin-lattice relaxation measurements revealed a low-frequency critical collective chain dynami... | ['Amines', 'Biophysical Phenomena', 'Biophysics', 'Chemical Phenomena', 'Chemistry, Physical', 'Lipid Bilayers', 'Magnetic Resonance Spectroscopy', 'Membrane Lipids', 'Models, Chemical', 'Temperature'] | 11,690,071 | [['D02.092'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['G02'], ['H01.181.529'], ['D10.570.510', 'J01.637.087.500.510'], ['E05.196.867.519'], ['D10.570'], ['E05.599.495'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Short-term potentiation of carotid chemoreflex: an NMDAR-dependent neural integrator. | Repetitive stimulation of the carotid sinus nerve (CSN) elicits a short-term potentiation (STP) of the reflex response in respiratory motor output in mammals. The input-output transformation approximates a leaky integrator with a time constant of several seconds. Here, we showed that STP induced by CSN stimulation in r... | ['Animals', 'Carotid Sinus', 'Chemoreceptor Cells', 'Electric Stimulation', 'Male', 'Models, Neurological', 'Periodicity', 'Phrenic Nerve', 'Rats', 'Rats, Sprague-Dawley', 'Reaction Time', 'Receptors, N-Methyl-D-Aspartate', 'Reflex', 'Respiratory Physiological Phenomena'] | 10,439,445 | [['B01.050'], ['A07.015.114.186.456'], ['A08.675.650.915.500', 'A08.800.950.500', 'A11.671.650.915.500'], ['E05.723.402'], ['E05.599.395.642'], ['G01.910.645', 'G07.180.562'], ['A08.800.800.720.150.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E05.796.817', 'F02.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Abnormal lung elasticity in juvenile diabetes mellitus. | Static lung pressure-volume curves, lung volumes, spirometry, diffusing capacity for CO, and airway and total pulmonary resistance were determined in 11 young men with juvenile-onset diabetes mellitus who were not cigarette smokers. Twelve nonsmoking men of similar age without diabetes served as control subjects. Elast... | ['Adult', 'Airway Resistance', 'Diabetes Mellitus, Type 1', 'Humans', 'Lung Compliance', 'Lung Volume Measurements', 'Male', 'Maximal Expiratory Flow Rate', 'Residual Volume', 'Spirometry', 'Total Lung Capacity'] | 1,247,213 | [['M01.060.116'], ['E01.370.386.700.050', 'G09.772.060'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.475', 'G09.772.540'], ['E01.370.386.700.485'], ['E01.370.386.700.660.225.500', 'G09.772.650.300.590'], ['E01.370.386.700.485.750.275.650', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Appendicitis in acquired immunodeficiency syndrome. | Reports in the surgical literature are few regarding common intra-abdominal disease processes, such as gallstone disease or appendicitis, in patients with AIDS and instead have focused on AIDS-related intra-abdominal diseases that infrequently require surgical intervention unless complicated by bleeding, obstruction, o... | ['AIDS-Related Opportunistic Infections', 'Acquired Immunodeficiency Syndrome', 'Adult', 'Appendicitis', 'Colitis', 'Cytomegalovirus Infections', 'Female', 'Follow-Up Studies', 'Humans', 'Laparotomy', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Time Factors'] | 1,332,523 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['C01.4... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Postpartum hemorrhage resulting from pelvic pseudoaneurysm: a retrospective analysis of 588 consecutive cases treated by arterial embolization. | OBJECTIVE: This study was designed to determine the incidence of arterial pseudoaneurysm in patients presenting with postpartum hemorrhage (PPH), to analyze the angiographic characteristics of pseudoaneurysms that cause PPH, and to evaluate the effectiveness of pelvic arterial embolization for the treatment of this con... | ['Adult', 'Aneurysm, False', 'Angiography, Digital Subtraction', 'Embolization, Therapeutic', 'Female', 'Humans', 'Iliac Artery', 'Postpartum Hemorrhage', 'Retrospective Studies', 'Treatment Outcome', 'Uterine Artery'] | 23,756,881 | [['M01.060.116'], ['C14.907.055.090'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.444'], ['C13.703.420.725', 'C13.703.844.700', 'C23.55... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An in vitro oral biofilm model for comparing the efficacy of antimicrobial mouthrinses. | The ability of commercial mouthrinses to reduce total viable counts of mixed microbial populations was examined using a previously developed in vitro model of supragingival plaque. Exploratory experiments aimed at fine-tuning the model indicated that optimal correspondence between in vitro and clinical results for chlo... | ['Anti-Infective Agents, Local', 'Bacteria', 'Biofilms', 'Chlorhexidine', 'Colony Count, Microbial', 'Dental Plaque', 'Drug Evaluation, Preclinical', 'Fluorides, Topical', 'Hexetidine', 'Microbial Sensitivity Tests', 'Models, Biological', 'Mouthwashes', 'Phenols', 'Plant Extracts', 'Pyridines', 'Saliva', 'Statistics, N... | 12,037,365 | [['D27.505.954.122.187'], ['B03'], ['A20.593', 'G06.120'], ['D02.078.370.141.100'], ['E01.370.225.875.220', 'E05.200.875.220'], ['C07.793.208.377'], ['E05.290.750', 'E05.337.550'], ['D01.303.350.300.512', 'D25.223.432', 'J01.637.051.223.432'], ['D03.383.742.279'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Fabricating nanoscale DNA patterns with gold nanowires. | Surface patterns of single-stranded DNA (ssDNA) consisting of nanoscale lines as thin as 40 nm were fabricated on polymer substrates for nanotechnology and bioaffinity sensing applications. Large scale arrays (with areas up to 4 cm(2)) of ssDNA "nanolines" were created on streptavidin-coated polymer (PDMS) surfaces by ... | ['DNA, Single-Stranded', 'Gold', 'Microscopy, Atomic Force', 'Microscopy, Fluorescence', 'Nanowires', 'Nucleic Acid Hybridization', 'Polymers'] | 20,337,428 | [['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['E01.370.350.515.458', 'E05.595.458'], ['J01.637.512.925'], ['E05.393.661', 'G02.111.611'], ['D05.750', 'D25.720', 'J01.637.051.720']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Growth factor involvement in the multihormonal regulation of MCF-7 breast cancer cell growth in soft agar. | The hormone dependency of the MCF-7 breast cancer cell line, while extensively tested in liquid culture, has not been previously evaluated under conditions of anchorage-independent growth in serum-free media. Using the soft agar clonogenic assay, we demonstrate that physiologically relevant concentrations of estradiol ... | ['Agar', 'Antibodies', 'Breast Neoplasms', 'Culture Media', 'Drug Interactions', 'Epidermal Growth Factor', 'Estradiol', 'Female', 'Growth Substances', 'Hormones', 'Humans', 'Insulin-Like Growth Factor I', 'Neoplasms, Hormone-Dependent', 'Progesterone', 'Prolactin', 'Tamoxifen', 'Transforming Growth Factor alpha', 'Tra... | 1,813,068 | [['D09.698.360.041'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['C04.588.180', 'C17.800.090.500'], ['D27.720.470.305', 'E07.206'], ['G07.690.773.968'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D04.210.500.365.415.248', 'D06.472.334... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Time-slot modulated electromagnetic fields of wireless communication systems: is there a health risk for man? | The safety guidelines of ICNIRP on bio-effects of low energy fields are based absorption and transformation into thermal effects. These guidelines are much higher than for acute reactions and long time exposure. It is pointed out that the guidelines for cordless telephone and mobile phone should correspond to long time... | ['Communication', 'Electromagnetic Fields', 'Humans', 'Risk Assessment', 'Telephone'] | 15,244,273 | [['F01.145.209', 'L01.143'], ['G01.358.500.260', 'G01.358.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['L01.178.847.698']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease. | Alzheimer's disease (AD) is the most common progressive dementia and is pathologically characterized by brain deposition of amyloid-beta (Abeta) peptide as senile plaques. Inflammatory and immune response pathways are chronically activated in AD patient brains at low levels, and likely play a role in disease progressio... | ['Alzheimer Disease', 'Amyloid beta-Protein Precursor', 'Animals', 'Astrocytes', 'Cerebral Amyloid Angiopathy', 'Cerebral Cortex', 'Cytokines', 'Disease Models, Animal', 'Female', 'Gene Expression Regulation', 'Gliosis', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Microglia', 'Nerve Growth Fact... | 19,705,461 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['C10.228.140.300.510.200.200', 'C14.907.253.560.200.200', 'C18.452.845.500.100'], ['A08.186.211.200.885.287.500'], ['D12.644... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrodermal Activity Sensor for Classification of Calm/Distress Condition. | This article introduces a new and unobtrusive wearable monitoring device based on electrodermal activity (EDA) to be used in health-related computing systems. This paper introduces the description of the wearable device capable of acquiring the EDA of a subject in order to detect his/her calm/distress condition from th... | ['Biofeedback, Psychology', 'Biosensing Techniques', 'Emotions', 'Galvanic Skin Response', 'Humans', 'Signal Processing, Computer-Assisted'] | 29,023,403 | [['E02.190.525.123', 'F02.830.131', 'F04.754.137.301', 'F04.754.308.500'], ['E05.601.043'], ['F01.470'], ['E05.796.332', 'F02.830.702.315', 'F04.669.332', 'G07.265.563', 'G13.750.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Lycopene in treatment of high-grade gliomas: a pilot study. | BACKGROUND: The therapeutic benefit of lycopene is well established for carcinoma prostate in various clinical trials and has been proposed for other malignancies including high-grade gliomas.SETTING AND DESIGN: Randomized placebo control study in the Department of Radiation Oncology of a teaching hospital.MATERIALS AN... | ['Administration, Oral', 'Adolescent', 'Adult', 'Aged', 'Analysis of Variance', 'Antioxidants', 'Brain Neoplasms', 'Carotenoids', 'Child', 'Double-Blind Method', 'Female', 'Follow-Up Studies', 'Glioma', 'Humans', 'Lycopene', 'Male', 'Middle Aged', 'Pilot Projects', 'Radiography', 'Radiotherapy', 'Retrospective Studies'... | 20,228,458 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Morphological studies on the effect of L-leucine methyl ester on mouse peritoneal macrophages in vitro. | Mouse peritoneal macrophages (MO) were treated in culture with 5 mM L-leucine methyl ester (L-Leu-OMe), for 5, 10, 20, 40, and 60 min. The treatment resulted in rapid vacuolisation of the cytoplasm due to the dilatation and disruption of lysosomes. Autophagy caused by lysosomal enzymes destroyed most of the cytoplasmic... | ['Animals', 'Cell Membrane', 'Cell Nucleus', 'Cells, Cultured', 'Cytoplasm', 'Formaldehyde', 'Leucine', 'Lysosomes', 'Macrophages', 'Male', 'Mice', 'Microscopy, Electron', 'Organelles', 'Peritoneal Cavity', 'Time Factors'] | 1,915,755 | [['B01.050'], ['A11.284.149'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['A11.284.430.214'], ['D02.047.407'], ['D12.125.070.637', 'D12.125.142.441'], ['A11.284.430.214.190.875.190.550'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemolytic anemia in patients receiving daily dapsone for the treatment of leprosy. | INTRODUCTION: Multidrug therapy for leprosy is currently done with dapsone, clofazimine and rifampicin. Dapsone is known to cause hemolytic anemia (HA) and this adverse event during MDT seems to be more frequent than reported. The aim of this report is to discuss and grade HA due to dapsone during MDT treatment for lep... | ['Adolescent', 'Adult', 'Aged', 'Anemia, Hemolytic', 'Brazil', 'Clofazimine', 'Dapsone', 'Drug Therapy, Combination', 'Female', 'Follow-Up Studies', 'Hematocrit', 'Hematologic Tests', 'Hemoglobins', 'Hemolysis', 'Humans', 'Leprostatic Agents', 'Leprosy', 'Male', 'Middle Aged', 'Retrospective Studies', 'Rifampin', 'Trea... | 23,356,031 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C15.378.071.141'], ['Z01.107.757.176'], ['D03.633.300.704.353'], ['D02.886.590.263'], ['E02.319.310'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['E01... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Purification and characterization of cytochrome P-450 with high affinity for 7-alkoxycoumarins. | A unique form of cytochrome P-450 (called P-450(2] with high affinity for 7-alkoxycoumarins was purified from liver microsomes of phenobarbital-treated rabbits with an overall yield of about 0.6%. The purified preparation had a specific cytochrome P-450 content of 15-16 nmol per mg of protein and was homogenous on sodi... | ['7-Alkoxycoumarin O-Dealkylase', 'Animals', 'Coumarins', 'Cytochrome P-450 Enzyme System', 'Microsomes, Liver', 'Molecular Weight', 'NADPH-Ferrihemoprotein Reductase', 'Oxygenases', 'Phenobarbital', 'Protein Binding', 'Rats', 'Substrate Specificity'] | 6,430,886 | [['D08.811.682.690.708.170.010.024'], ['B01.050'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A11.284.835.540.541'], ['G02.494'], ['D08.811.682.608.191.500'], ['D08.811.682.690'], ['D03.383.742.698.253.650'], ['G02.111.679', 'G03.808'], ['B01.050... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gains in fluid intelligence after training non-verbal reasoning in 4-year-old children: a controlled, randomized study. | Fluid intelligence (Gf) predicts performance on a wide range of cognitive activities, and children with impaired Gf often experience academic difficulties. Previous attempts to improve Gf have been hampered by poor control conditions and single outcome measures. It is thus still an open question whether Gf can be impro... | ['Child, Preschool', 'Cognition', 'Education', 'Executive Function', 'Female', 'Humans', 'Intelligence', 'Intelligence Tests', 'Learning', 'Male', 'Memory, Short-Term', 'Problem Solving'] | 21,477,197 | [['M01.060.406.448'], ['F02.463.188'], ['I02'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.543'], ['F04.711.141.493'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.425.540.407'], ['F02.463.425.725', 'F02.463.785.810']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Biocomposites of non-crosslinked natural and synthetic polymers. | Biocomposite films comprising a non-crosslinked, natural polymer (collagen) and a synthetic polymer, poly(epsilon-caprolactone) (PCL), have been produced by impregnation of lyophilised collagen mats with a solution of PCL in dichloromethane followed by solvent evaporation. This approach avoids the toxicity problems ass... | ['Biocompatible Materials', 'Cell Adhesion', 'Cells, Cultured', 'Collagen', 'Collagenases', 'Cross-Linking Reagents', 'Humans', 'Microscopy, Electron, Scanning', 'Osteoblasts', 'Polyesters', 'Polymers'] | 11,962,651 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['G04.022'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D08.811.277.656.300.480.205', 'D08.811.277.656.675.374.205'], ['D27.720.470.410.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A11.329.62... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Online personalized feedback intervention for cannabis-using college students reduces cannabis-related problems among women. | There is growing evidence that college cannabis use is associated with use-related problems, yet efforts to reduce cannabis-related problems via online personalized feedback interventions (PFIs) have had limited success in significantly reducing risky cannabis use among college students. However, men and women may resp... | ['Adult', 'Feedback, Psychological', 'Female', 'Follow-Up Studies', 'Humans', 'Internet', 'Male', 'Marijuana Use', 'Sex Factors', 'Students', 'Therapy, Computer-Assisted', 'Treatment Outcome', 'Universities', 'Young Adult'] | 31,302,314 | [['M01.060.116'], ['F01.058.288', 'F04.754.308'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['F01.145.610', 'F03.900.643'], ['N05.715.350.675', 'N06.850.490.875'], ['M01.848'], ['E02.950', 'L01.313... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 |
[The influence of N-acetyl-L-cysteine on pulmonary injury and oxygen stress after smoke inhalation injury]. | OBJECTIVE: To investigate the influence of N-acetyl-L-cysteine (NAC) on pulmonary injury and oxygen stress caused by smoke inhalation injury.METHODS: Rats inflicted with smoke inhalation injury were employed as the model. WBC in BALF (bronchoalveolar lavage fluid), MPO (myeloperoxidase) activity, hydrogen peroxide (H(2... | ['Acetylcysteine', 'Animals', 'Bronchoalveolar Lavage Fluid', 'Disease Models, Animal', 'Free Radical Scavengers', 'Glutathione', 'Hydrogen Peroxide', 'Leukocytes', 'Oxidative Stress', 'Peroxidase', 'Rats', 'Rats, Wistar', 'Smoke Inhalation Injury'] | 12,460,510 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['B01.050'], ['E05.927.100.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.505.519.217.500'], ['D12.644.456.448'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['A11.118.637', 'A15.145.229.637', 'A15.382.49... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of serum levels of inflammatory markers and allelic variant of interleukin-6 in patients with acute coronary syndrome and stable angina pectoris. | OBJECTIVES: Although the relationship between atherosclerosis and inflammatory cells has been recognized in recent years, the effect of interleukin-6 (IL-6) genetic variants associated with atherosclerosis is still controversial. Therefore, we investigated the association between IL-6 polymorphism and levels of IL-6 in... | ['Acute Coronary Syndrome', 'Adult', 'Aged', 'Angina Pectoris', 'Biomarkers', 'C-Reactive Protein', 'Case-Control Studies', 'Chi-Square Distribution', 'Female', 'Humans', 'Inflammation', 'Interleukin-6', 'Male', 'Middle Aged', 'Mutation', 'Polymorphism, Genetic'] | 18,281,810 | [['C14.280.647.124', 'C14.907.585.124'], ['M01.060.116'], ['M01.060.116.100'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.9... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Immunochemical and electron microscopic analysis of the high-molecular structures in the tick-borne encephalitis virus]. | High-molecular structures of tick-borne encephalitis virus were sedimented by centrifugation from virus-containing culture fluid and separated by sucrose concentration gradient centrifugation into 3 main fractions: rapidly sedimenting virions, the fraction sedimenting at a moderate rate, represented by "stellate" struc... | ['Centrifugation, Density Gradient', 'Encephalitis Viruses, Tick-Borne', 'Immunochemistry', 'Immunodiffusion', 'Immunoelectrophoresis', 'Macromolecular Substances', 'Microscopy, Electron'] | 3,933,182 | [['E05.181.724.336', 'E05.196.941.336'], ['B04.820.230.511', 'B04.820.578.344.350.350'], ['H01.158.201.486', 'H01.181.122.605', 'H02.403.044.500'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ['E01.370.225.812.735.645.350.350', 'E05.196.401.568', 'E05.20... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cellular expression of (R127W)HSPB1 and its co-localization with neurofilament light chain]. | OBJECTIVE: To observe the cellular expression of (R127W) HSPB1 and its influence on neurofilament light chain (NFL) self-assembly and co-localization with NFL.METHODS: Eukaryotic expression vectors pEGFPN1-(wt) HSPB1 and pEGFPN1- (R127W) HSPB1 were constructed. Hela cells were transiently transfected with pEGFPN1-(wt) ... | ['Base Sequence', 'Charcot-Marie-Tooth Disease', 'Gene Expression Regulation', 'Genetic Vectors', 'HSP27 Heat-Shock Proteins', 'HeLa Cells', 'Heat-Shock Proteins', 'Humans', 'Intracellular Space', 'Molecular Chaperones', 'Mutant Proteins', 'Neurofilament Proteins', 'Protein Binding', 'Protein Transport', 'Transfection'... | 21,983,720 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['G05.308'], ['G05.360.337'], ['D12.776.580.216.270.625'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['D12.776.580.216'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Synthesis of polysubstituted 5-azaindoles via palladium-catalyzed heteroannulation of diarylalkynes. | A general and efficient procedure for the synthesis of functionalized 5-azaindoles through the catalyzed heteroannulation of 4-acetamido-3-iodopyridines and diarylalkynes is described. The reaction allows the preparation of a variety of substituted 2,3-diaryl-5-azaindoles in good to excellent yields. | ['Alkynes', 'Aza Compounds', 'Catalysis', 'Indoles', 'Palladium', 'Pyridines'] | 21,500,844 | [['D02.455.326.397'], ['D02.145'], ['G02.130'], ['D03.633.100.473'], ['D01.268.556.680', 'D01.268.956.718', 'D01.552.544.680'], ['D03.383.725']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optical coherence tomography measurements of the fresh porcine eye and response of the outer coats of the eye to volume increase. | Corneal and scleral thickness and anterior chamber dimensions are required for understanding developmental and pathological processes. Parameters of the eyeball are also required to calculate optical and material properties. As the eyeball resembles a pressure vessel, it has been suggested that elasticity of the cornea... | ['Animals', 'Computer Simulation', 'Image Interpretation, Computer-Assisted', 'In Vitro Techniques', 'Models, Biological', 'Organ Size', 'Sclera', 'Swine', 'Tomography, Optical Coherence'] | 18,465,965 | [['B01.050'], ['L01.224.160'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E05.481'], ['E05.599.395'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['A09.371.784'], ['B01.050.150.900.649.313.500.880'], ['E01.370.350.589.249.500', 'E01.370.350.825.805.500... | ['Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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