Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Bias-corrected maximum likelihood estimator of the intraclass correlation parameter for binary data. | A popular model to analyse over/under-dispersed proportions is to assume the extended beta-binomial model with dispersion (intraclass correlation) parameter phi and then to estimate this parameter by maximum likelihood. However, it is well known that maximum likelihood estimate (MLE) may be biased when the sample size ... | ['Animals', 'Bias', 'Biometry', 'Chromosome Aberrations', 'Data Interpretation, Statistical', 'Humans', 'Likelihood Functions', 'Mathematics', 'Models, Statistical', 'Nuclear Warfare', 'Toxicology'] | 16,007,569 | [['B01.050'], ['N05.715.350.150', 'N06.850.490.500'], ['E05.318.740.225', 'N06.850.505.200'], ['C23.550.210', 'G05.365.590.175'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318... | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Risk factors for death in patients admitted to hospital with asthma: a follow-up study. | Hospital records of patients with asthma admitted to teaching hospitals in Perth, Western Australia between 1976 and 1980 were examined retrospectively to identify characteristics of the illness which were associated with subsequent death. From 5722 admissions there were 195 deaths to December 1982, 186 of whom had rec... | ['Adolescent', 'Adult', 'Asthma', 'Australia', 'Carbon Dioxide', 'Child', 'Child, Preschool', 'Follow-Up Studies', 'Hospitalization', 'Humans', 'Middle Aged', 'Oxygen', 'Respiratory Mechanics', 'Retrospective Studies', 'Risk Factors'] | 1,759,915 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['Z01.639.100', 'Z01.678.100.373'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.35... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Tamoxifen inhibits GH3 cell growth in culture via enhancement of apoptosis. | OBJECTIVE: To investigate the antitumor effects of tamoxifen on pituitary tumor GH3 cells, which lack receptors for dopamine.METHODS: GH3 cells were treated with tamoxifen (10(-7) mol/L), bromocriptine (10(-8) mol/L), or a combination of tamoxifen and bromocriptine in serum-free media. The cell number, bromodeoxyuridin... | ['Animals', 'Antineoplastic Agents, Hormonal', 'Apoptosis', 'Bromocriptine', 'Cell Count', 'Cell Division', 'Dopamine Agonists', 'Estradiol', 'Humans', 'Microscopy, Electron', 'Neoplasms, Radiation-Induced', 'Pituitary Neoplasms', 'Prolactin', 'Rats', 'Receptors, Dopamine', 'Tamoxifen', 'Tumor Cells, Cultured'] | 9,657,197 | [['B01.050'], ['D27.505.954.248.169'], ['G04.146.954.035'], ['D03.132.327.412.100', 'D03.633.400.439.131', 'D03.633.400.562.100'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D27.505.519.625.150.151', 'D27.505.696.577.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Normalization of growth in hypophysectomized mice using hydrodynamic transfer of the human growth hormone gene. | Nonviral gene transfer was investigated as a potential treatment of growth hormone deficiency (GHD) using hypophysectomized mice as a model. After a single hydrodynamic administration of naked plasmid DNA containing the human growth hormone (hGH) gene controlled by an ubiquitin promoter, sustained elevation of circulat... | ['Animals', 'DNA', 'Gene Expression', 'Growth', 'Human Growth Hormone', 'Humans', 'Hypophysectomy', 'Insulin-Like Growth Factor Binding Protein 3', 'Insulin-Like Growth Factor I', 'Liver', 'Lung', 'Male', 'Mice', 'Organ Size', 'Plasmids', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Spleen', 'Tail', 'Tibia', 'Transf... | 12,657,568 | [['B01.050'], ['D13.444.308'], ['G05.297'], ['G07.345.249'], ['D06.472.699.631.525.425.875', 'D12.644.548.691.525.425.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.270.532', 'E04.525.400'], ['D12.776.157.420.270'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Influence of Hippocampal Dopamine D2 Receptors on Episodic Memory Is Modulated by BDNF | Episodic memory is a polygenic trait influenced by different molecular mechanisms. We used PET and a candidate gene approach to investigate how individual differences at the molecular level translate into between-person differences in episodic memory performance of elderly persons. Specifically, we examined the interac... | ['Aged', 'Brain-Derived Neurotrophic Factor', 'Female', 'Hippocampus', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Male', 'Memory, Episodic', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Positron-Emission Tomography', 'Receptors, Dopamine D2'] | 31,112,471 | [['M01.060.116.100'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['F02.463.425.540.254'], ['M01.060.116.630'], ['G05.365.795.598'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The relationship between intracellular Ca2+ and the mitochondrial membrane potential in isolated proximal tubular cells from rat kidney exposed to the nephrotoxin 1,2-dichlorovinyl-cysteine. | The effects of 1,2-dichlorovinyl-cysteine (DCVC) on the intracellular free calcium concentration ([Ca2+]i) and the mitochondrial membrane potential (delta phi) were investigated in freshly isolated rat kidney proximal tubular cells (PTC). Prior to cell death, DCVC induced a rise in [Ca2+]i and a decrease in the delta p... | ['Aminoquinolines', 'Animals', 'Calcium', 'Cysteine', 'Edetic Acid', 'Egtazic Acid', 'Flow Cytometry', 'Kidney Tubules, Proximal', 'Male', 'Membrane Potentials', 'Mitochondria', 'Rats', 'Rats, Wistar', 'Time Factors'] | 8,517,866 | [['D03.633.100.810.050'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['E01.370.225.500.363.342', 'E01.370.225.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acromegaly and papillomatosis: difficult intubation and use of the airway exchange catheter. | We describe the anaesthetic management of a patient with acromegaly scheduled for transsphenoidal resection of a pituitary tumour who was found at intubation to have coexisting laryngeal papillomatosis. Oral intubation was impossible using both direct and fibreoptic techniques. Nasal fibreoptic intubation was successfu... | ['Acromegaly', 'Contraindications', 'Female', 'Humans', 'Intubation, Intratracheal', 'Laryngeal Neoplasms', 'Middle Aged', 'Papilloma', 'Tracheostomy'] | 10,460,532 | [['C05.116.132.082', 'C10.228.140.617.738.250.100', 'C19.700.355.179'], ['E02.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['M01.060.116.630'], ['C04.557.470.700.600'], ['E02.04... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Semantic priming by pictures and words in the cerebral hemispheres. | In order to determine whether pictures would act as more effective semantic primes than words in the right cerebral hemisphere, automatic semantic activation in intact hemispheres was studied with primed GO-NOGO lexical decision tasks by presenting word-word and picture-word pairs to the left visual field (right hemisp... | ['Adult', 'Association Learning', 'Cues', 'Dominance, Cerebral', 'Female', 'Humans', 'Language', 'Male', 'Memory', 'Photic Stimulation', 'Reaction Time', 'Semantics', 'Visual Fields'] | 10,978,696 | [['M01.060.116'], ['F02.463.425.069.296'], ['F02.463.425.234'], ['F02.830.297', 'G11.561.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F02.463.425.540'], ['E05.723.729'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['L01.559.598.745'], ['F02.463.593.932.934'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
International Multicentre Term Prelabor Rupture of Membranes Study: evaluation of predictors of clinical chorioamnionitis and postpartum fever in patients with prelabor rupture of membranes at term. | OBJECTIVES: Our purpose was to determine significant predictors for the development of clinical chorioamnionitis and postpartum fever in patients with prelabor rupture of membranes at term.STUDY DESIGN: Logistic regression analysis with odds ratios and 95% confidence intervals was used to determine the significant pred... | ['Adult', 'Chorioamnionitis', 'Female', 'Fetal Membranes, Premature Rupture', 'Fever', 'Humans', 'Pregnancy', 'Prospective Studies', 'Puerperal Disorders', 'Regression Analysis'] | 9,396,886 | [['M01.060.116'], ['C13.703.277.030', 'C13.703.420.339.260', 'C13.703.590.268', 'C16.300.030'], ['C13.703.420.339'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C13.703.844'], ['E0... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lung cancer cell line sensitivity to Zoledronic acid is BAX-dependent. | BACKGROUND: Zoledronate (Zol), an anti-osteoclastic and anticancer drug, is used to control bone metastasis in several cancer types, including non-small cell lung cancer (NSCLC). However, the mechanisms behind Zol resistance in NSCLC are unclear.MATERIALS AND METHODS: Zol-resistant cell lines were developed by repeated... | ['Apoptosis', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'Cell Proliferation', 'Diphosphonates', 'Enzyme-Linked Immunosorbent Assay', 'Flow Cytometry', 'Humans', 'Imidazoles', 'Lung Neoplasms', 'RNA Interference', 'Zoledronic Acid', 'bcl-2-Associated X Protein'] | 24,324,070 | [['G04.146.954.035'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.705.429.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells. | Chelatable, mobile forms of divalent zinc, Zn(II), play essential signaling roles in mammalian biology. A complex network of zinc import and transport proteins has evolved to control zinc concentration and distribution on a subcellular level. Understanding the action of mobile zinc requires tools that can detect change... | ['Cell Line, Tumor', 'Endosomes', 'Female', 'Fluoresceins', 'Fluorescent Dyes', 'HeLa Cells', 'Humans', 'Hydrogen-Ion Concentration', 'Lysosomes', 'Male', 'Microscopy, Fluorescence', 'Mitochondria', 'Prostate', 'Prostatic Neoplasms', 'Time Factors', 'Zinc'] | 24,335,702 | [['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.214.190.875.190.880.337'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Highlights Regarding Host Predisposing Factors to Recurrent Vulvovaginal Candidiasis: Chronic Stress and Reduced Antioxidant Capacity. | We studied host factors that could predispose women to develop recurrent vulvovaginal candidiasis (RVVC), including glycemia, insulin resistance, chronic stress, antioxidant capacity, overall immune status, local inflammation and vaginal microbiota. The presence of yeasts in vaginal culture was screened in 277 women, w... | ['Adolescent', 'Adult', 'Antioxidants', 'Blood Glucose', 'Candida albicans', 'Candidiasis, Vulvovaginal', 'Female', 'Humans', 'Inflammation', 'Insulin Resistance', 'Microbiota', 'Prospective Studies', 'Recurrence', 'Risk Factors', 'Stress, Psychological', 'Vagina', 'Young Adult'] | 27,415,762 | [['M01.060.057'], ['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D09.947.875.359.448.500'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['C01.150.703.160.190', 'C13.351.500.894.906.820.500', 'C13.351.500.944.902.737.500'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Care needs of home-based cancer patients and their caregivers. Quantitative findings. | The purpose of this study was to identify care needs of home-based patients receiving treatment for cancer and their caregivers. The sample consisted of 30 patients receiving radiation therapy and/or immunologically based treatments for a variety of cancers and 29 caregivers. Patient and caregiver needs scales were use... | ['Aged', 'Aged, 80 and over', 'Caregivers', 'Female', 'Health Services Needs and Demand', 'Home Nursing', 'Humans', 'Immunologic Factors', 'Male', 'Middle Aged', 'Neoplasms', 'Nursing Methodology Research', 'Surveys and Questionnaires'] | 1,611,603 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['N03.349.380.420', 'N05.300.450'], ['E02.760.611.470', 'N02.421.143.524.470', 'N02.421.533.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477'], ['M01.060.116.630'], ['C04'], ['H01.770.644.145.390.634',... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Occurrence of low molecular weight O-acetylserine sulfhydrylase in the yeast Saccharomyces cerevisiae. | Studies with crude preparations obtained from a cysteine auxotroph of Saccharomyces cerevisiae showed that O-acetylserine sulfhydrylase could be separated from O-acetylhomoserine sulfhydrylase by chromatography on a DEAE-cellulose column and centrifugation in a sucrose density gradient. On the basis of sedimentation di... | ['Carbon-Oxygen Lyases', 'Centrifugation, Density Gradient', 'Chromatography, DEAE-Cellulose', 'Cysteine Synthase', 'Homoserine', 'Hydrogen Sulfide', 'Lyases', 'Molecular Weight', 'Multienzyme Complexes', 'Mutation', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 7,007,360 | [['D08.811.520.241'], ['E05.181.724.336', 'E05.196.941.336'], ['E05.196.181.400.383.349'], ['D08.811.913.225.224'], ['D12.125.526'], ['D01.029.260.340', 'D01.362.350', 'D01.875.350'], ['D08.811.520'], ['G02.494'], ['D05.500.562', 'D08.811.600'], ['G05.365.590'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Birth ball or heat therapy? A randomized controlled trial to compare the effectiveness of birth ball usage with sacrum-perineal heat therapy in labor pain management. | OBJECTIVE: Labor pain and its management is a major concern for childbearing women, their families and health care providers. This study aimed to investigate the effects of two non-pharmacological methods such as birth ball and heat therapy on labor pain relief.MATERIAL & METHODS: This randomized control trial was unde... | ['Adolescent', 'Adult', 'Complementary Therapies', 'Exercise Movement Techniques', 'Female', 'Hot Temperature', 'Humans', 'Labor Pain', 'Labor Stage, First', 'Labor, Obstetric', 'Movement', 'Pain Management', 'Pain Measurement', 'Pelvis', 'Perineum', 'Physical Therapy Modalities', 'Posture', 'Pregnancy', 'Sacrum', 'Sev... | 27,502,808 | [['M01.060.057'], ['M01.060.116'], ['E02.190'], ['E02.779.474'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.451'], ['G08.686.784.769.326.500.080'], ['G08.686.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Macrophage colony-stimulating factor-induced macrophage differentiation promotes regrowth in atrophied skeletal muscles and C2C12 myotubes. | Skeletal muscle injury and regeneration are closely associated with an inflammatory reaction that is usually characterized by sequential recruitment of neutrophils and monocytes or macrophages. Selective macrophage depletion models have shown that macrophages are essential for complete regeneration of muscle fibers aft... | ['Animals', 'Bone Marrow Cells', 'Cell Differentiation', 'Cells, Cultured', 'Coculture Techniques', 'Macrophage Colony-Stimulating Factor', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Models, Animal', 'Muscle Contraction', 'Muscle Development', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Muscular Atrophy'... | 23,201,131 | [['B01.050'], ['A11.148', 'A15.378.316'], ['G04.152'], ['A11.251'], ['E05.481.500.374'], ['D12.644.276.374.410.240.500', 'D12.776.395.240.500', 'D12.776.467.374.410.240.500', 'D23.529.374.410.240.500'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.63... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Selection criteria in metabolic systems]. | In a given environment the physico-chemical parameters of a metabolic system are externally prescribed constant quantities. The living cell, however, is able to regulate the catalytic activities through its programme of gene expression. The paper investigates to what extent this programme is amenable to optimization by... | ['Biological Evolution', 'Cell Division', 'Cells', 'Gene Expression Regulation', 'Metabolism', 'Models, Biological', 'Protein Biosynthesis'] | 6,721,877 | [['G05.045', 'G16.075'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11'], ['G05.308'], ['G03'], ['E05.599.395'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extruded lumbar disc associated with epidural hematoma. Case report. | Lumbar disc herniation and spinal epidural hematomas (SEHs) are highly unusual causes of secondary lumbar canal stenosis in the adolescent population. The authors report a unique concomitant occurrence in a 16-year-old boy who presented with left-sided L-5 radiculopathy. Magnetic resonance imaging T1-weighted sequences... | ['Adolescent', 'Hematoma, Epidural, Spinal', 'Humans', 'Intervertebral Disc Displacement', 'Laminectomy', 'Lumbar Vertebrae', 'Magnetic Resonance Imaging', 'Male', 'Neurologic Examination', 'Spinal Cord Compression', 'Spinal Nerve Roots'] | 16,619,642 | [['M01.060.057'], ['C23.550.414.838.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.307', 'C23.300.707.952'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['A02.835.232.834.519'], ['E01.370.350.825.500'], ['E01.370.376.550', 'E01.370.600.550'], ['C10.228.854.761', 'C26.819.678'], ... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gold Medal Award for Life Achievement in Psychology in the Public Interest. | The American Psychological Foundation (APA) Gold Medal Awards recognize distinguished and enduring records of accomplishment in four areas of psychology: the application of psychology, the practice of psychology, psychology in the public interest, and the science of psychology. The 2008 recipient of the American Psycho... | ['Awards and Prizes', 'Consumer Advocacy', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Psychology', 'United States'] | 18,665,669 | [['K01.150'], ['I01.880.604.473.368', 'N03.706.437.368'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.096.628'], ['Z01.107.567.875']] | ['Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Differential antioxidative responses to cadmium in roots and leaves of pea (Pisum sativum L. cv. Azad). | Pea (Pisum sativum L. cv. Azad) plants exposed to 4 and 40 microM of Cd for 7 d in hydroponic culture were analysed with reference to the distribution of metal, the accumulation of biomass and the metal's effects on antioxidants and antioxidative enzymes in roots and leaves. Cd-induced a decrease in plant biomass. The ... | ['Antioxidants', 'Cadmium', 'Peas', 'Plant Roots', 'Plant Stems'] | 11,432,926 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['B01.650.940.800.575.912.250.401.630'], ['A18.400'], ['A18.024.937']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevention of unintentional injury in the community setting. | This article focuses on the types of unintentional injuries that may occur in the community and individuals who are most vulnerable. It discusses the nurse's role in the prevention of injuries through the assessment of risk and health promotion strategies. | ['Accident Prevention', 'Aged', 'Causality', 'Child', 'Community Health Nursing', 'Data Collection', 'Health Behavior', 'Health Knowledge, Attitudes, Practice', 'Health Policy', 'Health Promotion', 'Humans', 'Models, Nursing', 'Models, Psychological', "Nurse's Role", 'Nursing Assessment', 'Patient Education as Topic', ... | 20,695,336 | [['N06.850.135.060'], ['M01.060.116.100'], ['N05.715.350.200', 'N06.850.490.625'], ['M01.060.406'], ['H02.478.676.150', 'N02.421.143.150'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F01.145.488'], ['F01.100.150.500', 'N05.300.150.410'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N... | ['Health Care [N]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
GABAergic system of the pineal organ of an elasmobranch (Scyliorhinus canicula): a developmental immunocytochemical study. | The present immunocytochemical study provides evidence of a previously unrecognized, rich, gamma-aminobutyric acid (GABA)-ergic innervation of the pineal organ in the dogfish (Scyliorhinus canicula). In this elasmobranch, the pineal primordium is initially detected at embryonic stage 24 and grows to form a long pineal ... | ['Animals', 'Biomarkers', 'Dogfish', 'Glutamate Decarboxylase', 'Immunohistochemistry', 'Nerve Fibers', 'Pineal Gland', 'Presynaptic Terminals', 'gamma-Aminobutyric Acid'] | 16,158,323 | [['B01.050'], ['D23.101'], ['B01.050.150.900.493.370.853.392'], ['D08.811.520.224.125.250'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.60... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuromyelitis optica (NMO) antibody positivity in patients with transverse myelitis and no visual manifestations. | BACKGROUND AND PURPOSE: To describe a subgroup of patients with IgG antibody to Aquaporin 4 Protein (AQP4) specific to neuromyelitis optica (NMO), who did not have clinical manifestations of optic nerve involvement at the time of diagnosis.METHODS: Assessment of five patients (four African Americans and one Latino) wit... | ['Administration, Oral', 'Adolescent', 'Adult', 'Aged, 80 and over', 'Antibodies, Antinuclear', 'Aquaporin 4', 'Autoantibodies', 'Child', 'Female', 'Glucocorticoids', 'Humans', 'Infusions, Intravenous', 'Iodide Peroxidase', 'Magnetic Resonance Imaging', 'Male', 'Methylprednisolone', 'Middle Aged', 'Myelitis, Transverse... | 18,432,545 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D12.776.157.530.400.500.040.468', 'D12.776.543.550.450.730.040.468', 'D12.776.543.585.400.730.040.577'], ['D12.776.124.486.485.114... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A comparison of Toxocara canis embryonation under controlled conditions in soil and hair. | Toxocara spp. eggs require a period of time under appropriate environmental conditions to become infective to definitive and paratenic hosts. Temperature and humidity are important factors known to affect the levels of development in soil. We aimed to investigate whether the eggs of T. canis could embryonate in dog hai... | ['Animals', 'Dogs', 'Embryo, Nonmammalian', 'Embryonic Development', 'Female', 'Hair', 'Humidity', 'Soil', 'Temperature', 'Toxocara canis'] | 22,335,837 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['A13.350', 'A16.331'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['A17.360'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G01.906.595', ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Risk of tuberculosis in high-rise and high density dwellings: an exploratory spatial analysis. | Studies have shown that socioeconomic and environmental factors have direct/indirect influences on TB. This research focuses on TB prevalence of Hong Kong in relation to its compact urban development comprising of high-rise and high-density residential dwellings caused by rapid population growth and limited land resour... | ['Environmental Pollution', 'Geographic Information Systems', 'Hong Kong', 'Housing', 'Humans', 'Population Density', 'Spatial Analysis', 'Tuberculosis', 'Ventilation'] | 23,453,769 | [['N06.850.460'], ['L01.313.500.750.300.314', 'L01.470.750.750.462'], ['Z01.252.474.164.450'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.224.600', 'N06.850.505.400.600'], ['E05.318.740.933', 'N05.715.360.750.746', 'N06.850.520.83... | ['Health Care [N]', 'Information Science [L]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Relationship between DNA fragmentation and apoptosis in the programmed cell death in the rat prostate following castration. | Previous studies have demonstrated that the rapid involution of the rat ventral prostate following castration involves the death of the androgen-dependent epithelial cells present within the gland and that this death is the result of a series of discrete biochemical steps. The degradation of genomic DNA into nucleosoma... | ['Animals', 'Cell Survival', 'DNA Damage', 'Endonucleases', 'Epithelium', 'Lymphocytes', 'Macrophages', 'Male', 'Mast Cells', 'Necrosis', 'Orchiectomy', 'Prostate', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 2,555,799 | [['B01.050'], ['G04.346'], ['G05.200'], ['D08.811.277.352.355'], ['A10.272'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['A11.329.427', 'A15.382.652'], ['C23.550.717'], ['E04.270.282.679', 'E04.950.165.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vocal fold pseudocyst: results of 46 cases undergoing a uniform treatment algorithm. | OBJECTIVES/HYPOTHESIS: To describe treatment results and identify predictors of the need for surgical intervention in patients with vocal fold pseudocyst.STUDY DESIGN: Retrospective cohort study with longitudinal followup via survey.METHODS: Clinical records were reviewed for demographic information, VHI-10 score, and ... | ['Adolescent', 'Adult', 'Aged', 'Algorithms', 'Behavior Therapy', 'Female', 'Follow-Up Studies', 'Humans', 'Laryngeal Edema', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Retrospective Studies', 'Treatment Outcome', 'Vocal Cords'] | 24,114,711 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['F04.754.137'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.360.313', 'C09.400.313'], ['E05.318.372.500.750.500', 'N05.715.360.330.50... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Internal fixation of ununited femoral neck fractures combined with muscle-pedicle bone grafting. | Fifty-six patients with ununited intracapsular fractures of the femoral neck were treated by internal fixation and muscle-pedicle bone grafting. All had some absorption of the femoral neck, and many had avascular necrosis of the femoral head. At operation the sclerosed surfaces of the fractures were freshened, the avas... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Female', 'Femoral Neck Fractures', 'Femur Head Necrosis', 'Follow-Up Studies', 'Fracture Fixation, Internal', 'Fractures, Ununited', 'Humans', 'Male', 'Middle Aged', 'Muscles', 'Postoperative Care', 'Surgical Flaps'] | 3,958,010 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['C26.404.061.425.500', 'C26.531.750.500', 'C26.558.276.425.500'], ['C05.116.852.175', 'C23.550.717.732.368'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300'], ['C26.404.468'], ['B01.0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular analysis of the microbiota in hard feces from healthy rabbits (Oryctolagus cuniculus) medicated with long term oral meloxicam. | BACKGROUND: Analgesia is often indicated in rabbits undergoing surgical procedures or suffering from various painful conditions and the most common adverse effects associated with NSAIDs occur in the gastrointestinal tract (GIT). The objective of this study was to determine the potential effect of long-term (21 days) m... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Bacteria', 'Feces', 'Female', 'Meloxicam', 'RNA, Bacterial', 'RNA, Ribosomal, 16S', 'Rabbits', 'Thiazines', 'Thiazoles'] | 24,618,207 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['B03'], ['A12.459'], ['D02.886.665.275', 'D02.886.675.448', 'D03.383.129.708.448', 'D03.383.855.275'], ['D13.444.735.473'], ['D13.444.735.686.670'], ['B01.050.150.900.649.313.968.700'], ['D02.886.665', 'D03.383.855'], ['D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[?⁸F]FDG-positron emission tomography coregistration with computed tomography scans for radiation treatment planning of lymphoma and hematologic malignancies. | PURPOSE: Positron emission-tomography (PET) using 2-[(18)F]fluoro-2-deoxyglucose (FDG-PET) increases sensitivity and specificity of disease detection in lymphoma and thus is standard in lymphoma management. This study examines the effects of coregistering FDG-PET and computed tomography (CT) (PET/CT) scans on treatment... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cancer Care Facilities', 'Female', 'Fluorodeoxyglucose F18', 'Hodgkin Disease', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Neoplasms, Plasma Cell', 'New York City', 'Positron-Emission Tomography', 'Radiopharmaceuticals', 'Radiotherapy Plannin... | 20,933,343 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N02.278.421.556.070'], ['D09.254.229.500'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['M01.060.116.630'], ['E01.... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
[Retinal circulation and ocular blood barrier in diabetic retinopathy]. | Macular capillary blood flow velocity, the score of fluorescein angiography in posterior region and aqueous flare intensity were investigated in 38 diabetics (41 eyes) and 6 normal subjects (6 eyes) to clarify the relationship among retinal circulation, blood-retinal barrier and blood-aqueous barrier. Macular capillary... | ['Adult', 'Aged', 'Aqueous Humor', 'Blood Flow Velocity', 'Blood-Retinal Barrier', 'Capillaries', 'Diabetic Retinopathy', 'Female', 'Fluorescein Angiography', 'Humans', 'Macula Lutea', 'Male', 'Middle Aged', 'Regional Blood Flow', 'Retinal Vessels'] | 1,621,615 | [['M01.060.116'], ['M01.060.116.100'], ['A09.371.060.067.070', 'A12.207.270.040'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A07.040', 'A09.371.729.055'], ['A07.015.461.165'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Estrogen-progestin replacement therapy and breast cancer risk: the Women's Health Study (United States). | OBJECTIVE: While there is substantial evidence that unopposed estrogen use increases the risk of breast cancer, there are limited data from epidemiologic studies on the impact of estrogen-progestin combinations. We therefore examined estrogen-progestin replacement therapy and breast cancer risk in the Women's Health St... | ['Breast Neoplasms', 'Confounding Factors, Epidemiologic', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Estrogen Replacement Therapy', 'Estrogens, Conjugated (USP)', 'Female', 'Humans', 'Linear Models', 'Middle Aged', 'Multivariate Analysis', 'Proportional Hazards Models', 'Prospective Studies', 'Risk As... | 12,462,550 | [['C04.588.180', 'C17.800.090.500'], ['N05.715.350.240', 'N06.850.490.718'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.452.150'], ['D06.472.334.851.437.988'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.... | ['Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Matrix metalloproteinases and their endogenous inhibitors during the implantation period in the rat uterus. | Rats were studied to determine if matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) were detectable in developing embryonic and uterine tissues during the implantation period; that is, Days 6-8 of pregnancy. Tissue extracts were studied by zymography, reverse zymography and Western blotting. Immuno... | ['Animals', 'Blotting, Western', 'Decidua', 'Doxycycline', 'Electrophoresis', 'Embryo Implantation', 'Enzyme Inhibitors', 'Female', 'Immunohistochemistry', 'Matrix Metalloproteinase 1', 'Matrix Metalloproteinase 2', 'Matrix Metalloproteinase 9', 'Matrix Metalloproteinase Inhibitors', 'Matrix Metalloproteinases', 'Pregn... | 11,101,274 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A05.360.319.679.490.373', 'A16.710.289'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['E05.196.401', 'E05.301.300'], ['G08.686.784.170.104.500'], ['D27.505.519.389'], ['E01.370.225.500.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence and correlates of hypertension in a subarctic Indian population. | BACKGROUND: In a cross-sectional survey of 704 Cree and Ojibwa Indians ages 20-64 in six northern Canadian communities, blood pressure was measured along with various anthropometric, dietary, biochemical, sociodemographic, and lifestyle data.METHODS: Two readings of systolic (SBP) and diastolic (DBP) pressures were obt... | ['Adult', 'Age Factors', 'Aged', 'Blood Pressure', 'Cross-Sectional Studies', 'Eating', 'Female', 'Humans', 'Hypertension', 'Indians, North American', 'Lipids', 'Male', 'Manitoba', 'Middle Aged', 'Obesity', 'Ontario', 'Physical Fitness', 'Risk Factors', 'Sex Factors'] | 1,871,077 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.283', 'G10.261.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.686.508.15... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Neurochemical evaluation of the striatum in symptomatic and recovered MPTP-treated cats. | Striatal neurochemistry and motor activity were assessed in cats treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and killed either when symptomatic for a Parkinson-like motor disorder or six weeks later, when showing significant motor recovery. The results of striatal neurochemical analyses showed dist... | ['1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine', 'Animals', 'Behavior, Animal', 'Catecholamines', 'Corpus Striatum', 'Female', 'Male', 'Motor Activity', 'Parkinson Disease, Secondary'] | 1,944,893 | [['D03.383.725.450'], ['B01.050'], ['F01.145.113'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['A08.186.211.200.885.287.249.487'], ['F01.145.632', 'G11.427.410.698'], ['C10.228.140.079.862.800', 'C10.228.662.600.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Homologous DNA pairing domain peptides of RecA protein: intrinsic propensity to form beta-structures and filaments. | The 20 amino acid residue peptides derived from RecA loop L2 have been shown to be the pairing domain of RecA. The peptides bind to ss- and dsDNA, unstack ssDNA, and pair the ssDNA to its homologous target in a duplex DNA. As shown by circular dichroism, upon binding to DNA the disordered peptides adopt a beta-structur... | ['Amino Acid Sequence', 'Circular Dichroism', 'DNA, Single-Stranded', 'DNA-Binding Proteins', 'Microscopy, Electron', 'Molecular Sequence Data', 'Peptide Fragments', 'Protein Conformation', 'Rec A Recombinases'] | 9,514,744 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.867.151'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D12.776.260'], ['E01.370.350.515.402', 'E05.595.402'], ['L01.453.245.667'], ['D12.644.541'], ['G02.111.570.820.709'], ['D08.811.739.650', 'D08.811.913.696.445.692']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Viewpoint: New physicians for a new century. | How to train competent and compassionate physicians has assumed a new urgency. The authors propose that these concerns be approached by radically restructuring the medical school curriculum in ways that place facts and skills within the context of ethics and values. Doing so will require that the positivist stance of m... | ['Communication', 'Education, Medical', 'Empathy', 'Humanism', 'Humans', "Physician's Role", 'Physician-Patient Relations'] | 16,306,277 | [['F01.145.209', 'L01.143'], ['I02.358.399'], ['F01.752.355', 'F01.752.543.500.500'], ['K01.752.566.479.174', 'N05.350.835'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.316.616.625.600'], ['F01.829.401.650.675', 'N05.300.660.625']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
[Levels of aspartate aminotransferase and alanine aminotransferase in two factories with various hepato-toxic risks]. | The Authors have studied AST and ALT enzymatic activities in the workers of two firms, the former of which (tannery) with a high and the latter (boot and shoe factory) with a low level of hepatic-toxic risk. The influence of various trouble factors such as age, sex and seniority was eliminated through appropriate stati... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Alanine Transaminase', 'Aspartate Aminotransferases', 'Chemical and Drug Induced Liver Injury', 'Female', 'Humans', 'Male', 'Middle Aged', 'Occupational Diseases', 'Risk', 'Sex Factors', 'Time Factors'] | 7,347,821 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D08.811.913.477.700.100'], ['D08.811.913.477.700.225'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C24'], ['E05.318.740.600.800', 'G17.680.750', '... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Using time to insensibility and estimated time of death to evaluate a nonpenetrating captive bolt, cervical dislocation, and blunt trauma for on-farm killing of turkeys. | The effectiveness of a pneumatic nonpenetrating captive bolt (Zephyr) was assessed for on-farm euthanasia of turkeys and compared with blunt force trauma, manual cervical dislocation, and mechanical cervical dislocation using a burdizzo. The Zephyr (n = 46) and burdizzo (n = 26) were evaluated in turkey hens (11.4 +/- ... | ['Animal Husbandry', 'Animals', 'Electroshock', 'Euthanasia, Animal', 'Female', 'Joint Dislocations', 'Male', 'Random Allocation', 'Turkeys', 'Wounds, Nonpenetrating'] | 20,548,061 | [['J01.040.090'], ['B01.050'], ['E05.723.402.403', 'F04.669.224'], ['E02.760.905.199.249.750', 'E05.335', 'N02.421.585.905.199.500.750'], ['C05.550.518', 'C26.289'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.248.350.800', 'B01.050.150.900.248.690.800'], ['C2... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
De Novo renal expression of macrophage migration inhibitory factor during the development of rat crescentic glomerulonephritis. | Macrophage migration inhibitory factor (MIF), a key mediator of the delayed-type hypersensitivity response, was originally thought to be produced by activated T cells. However, recent studies have found that MIF is produced in many cell types including monocytes/macrophages and anterior pituitary cells. The current stu... | ['Animals', 'Disease Models, Animal', 'Glomerulonephritis', 'Kidney Glomerulus', 'Kidney Tubules', 'Macrophage Activation', 'Macrophage Migration-Inhibitory Factors', 'Male', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Time Factors'] | 8,863,661 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['A05.810.453.736.560'], ['G12.287.500'], ['D12.644.276.374.480.625', 'D12.776.467.374.480.625', 'D23.125.477.500', 'D23.529.374.480.625'], ['D13.444.735.544']... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Combined ab initio computational and experimental multinuclear solid-state magnetic resonance study of phenylphosphonic acid. | 1H, 13C, 17O and 31P NMR parameters, including chemical shift tensors and quadrupolar parameters for 17O, were calculated for phenylphosphonic acid, C6H5PO(OH)2, under periodic boundary conditions. The results are in very good agreement with experimental data and permit the unambiguous assignment of all the sites prese... | ['Algorithms', 'Computer Simulation', 'Crystallography', 'Magnetic Resonance Spectroscopy', 'Models, Chemical', 'Models, Molecular', 'Organophosphorus Compounds', 'Powders', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 15,095,380 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E05.196.309', 'H01.181.529.240'], ['E05.196.867.519'], ['E05.599.495'], ['E05.599.595'], ['D02.705'], ['D26.255.779'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Discovering high mobility group A molecular partners in tumour cells. | DNA-based activities rely on an extremely coordinated sequence of events performed by several chromatin-associated proteins which act in concert. High Mobility Group A (HMGA) proteins are non-histone architectural nuclear factors that participate in the regulation of specific genes but they are also believed to have a ... | ['Cell Line, Tumor', 'Chromatin', 'Chromatography, Affinity', 'Electrophoresis, Gel, Two-Dimensional', 'Glutathione Transferase', 'HMGA Proteins', 'Humans', 'Protein Binding', 'Protein Structure, Tertiary', 'Proteome', 'RNA, Messenger', 'Recombinant Proteins', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ioniz... | 15,798,993 | [['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['E05.196.181.400.170'], ['E05.196.401.250', 'E05.301.300.230'], ['D08.811.913.225.500'], ['D12.776.260.312', 'D12.776.660.235.400.500', 'D12.776.664.235.400.500'], ['B01.050.150.900.649.313.988.400.1... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of conditioning horses with lactate-guided exercise on muscle glycogen content. | The effects of 3 different conditioning programmes on muscle glycogen concentration in horses were examined. Speed of exercise was selected according to the blood lactate values for each horse derived from a standardised exercise test before beginning a conditioning programme. Six 2-year-old Haflinger stallions were as... | ['Animals', 'Biopsy', 'Exercise Test', 'Glycogen', 'Horses', 'Lactic Acid', 'Male', 'Muscles', 'Physical Conditioning, Animal', 'Random Allocation'] | 10,659,277 | [['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['D05.750.078.562.388', 'D09.698.365.388'], ['B01.050.150.900.649.313.984.235.472'], ['D02.241.511.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparative distribution of glyceraldehyde 3-phosphate dehydrogenase activity in human, guinea-pig, rabbit and mouse erythrocytes. | 1. Guinea-pig erythrocytes contain half the activity of the enzyme glyceraldehyde-3-phosphate dehydrogenase (G3PD) present in human cells. About 60% of their total activity is membrane-bound. 2. Rabbit erythrocytes also contain half the amount of the enzyme of human red cells. The distribution of G3PD in rabbit cells, ... | ['Animals', 'Erythrocyte Membrane', 'Erythrocytes', 'Glyceraldehyde-3-Phosphate Dehydrogenases', 'Guinea Pigs', 'Humans', 'Mice', 'Rabbits', 'Species Specificity'] | 3,665,431 | [['B01.050'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D08.811.682.657.163.750'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.968.70... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985) | During the investigational use of oral N-acetylcysteine as an antidote for poisoning with acetaminophen, 11,195 cases of suspected acetaminophen overdose were reported. We describe the outcomes of 2540 patients with acetaminophen ingestions treated with a loading dose of 140 mg of oral N-acetylcysteine per kilogram of ... | ['Acetaminophen', 'Acetylcysteine', 'Administration, Oral', 'Humans', 'Liver', 'Mortality', 'Multicenter Studies as Topic', 'Time Factors', 'Transaminases'] | 3,059,186 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D02.886.030.230.259', 'D12.125.166.230.259'], ['E02.319.267.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550'], ['E05.318.372.658', 'N05.715.360.330.6... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model. | Kennedy disease, a degenerative disorder characterized by androgen-dependent neuromuscular weakness, is caused by a CAG/glutamine tract expansion in the androgen receptor (Ar) gene. We developed a mouse model of Kennedy disease, using gene targeting to convert mouse androgen receptor (AR) to human sequence while introd... | ['Androgens', 'Animals', 'Chloride Channels', 'Disease Models, Animal', 'Female', 'Gene Expression', 'Glial Cell Line-Derived Neurotrophic Factor', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Muscle, Skeletal', 'Muscular Atrophy, Spinal', 'Mutation', 'Myogenin', 'NAV1.4 Voltage-Gated Sodium Cha... | 16,981,011 | [['D27.505.696.399.472.161'], ['B01.050'], ['D12.776.157.530.400.175', 'D12.776.543.550.450.175', 'D12.776.543.585.400.175'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.297'], ['D12.644.276.860.381.500', 'D12.776.467.860.381.500', 'D12.776.631.600.381.500', 'D23.529.850.381.500'], ['B01.050.150.900.649.313.98... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
MaizeGDB: The Maize Genetics and Genomics Database. | MaizeGDB is the community database for biological information about the crop plant Zea mays. Genomic, genetic, sequence, gene product, functional characterization, literature reference, and person/organization contact information are among the datatypes stored at MaizeGDB. At the project's website ( http://www.maizegdb... | ['Computational Biology', 'Databases, Genetic', 'Genomics', 'Web Browser', 'Zea mays'] | 26,519,406 | [['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['L01.224.900.940', 'L01.470.937'], ['B01.650.940.800.575.912.250.822.966']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Emergence of Resistance to Fungicides: The Role of Fungicide Dose. | Resistance to antimicrobial drugs allows pathogens to survive drug treatment. The time taken for a new resistant mutant to reach a population size that is unlikely to die out by chance is called "emergence time." Prolonging emergence time would delay loss of control. We investigate the effect of fungicide dose on the e... | ['Ascomycota', 'Azoles', 'Drug Resistance, Fungal', 'Fungicides, Industrial', 'Host-Pathogen Interactions', 'Models, Theoretical', 'Mutation', 'Plant Diseases', 'Triticum'] | 28,079,455 | [['B01.300.107'], ['D03.383.129'], ['G06.225.383', 'G07.690.773.984.269.383'], ['D27.720.031.700.288', 'D27.888.723.288'], ['G06.462', 'G16.527.200'], ['E05.599'], ['G05.365.590'], ['G15.610'], ['B01.650.940.800.575.912.250.822.918']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Parital microflora of human intestine]. | The modified method of the microbiological study of parietal mucin has been developed. The proposed method makes it possible to evaluate the parietal microflora of the intestine. The advantages of using physiological saline and Hanks' solution as medium ensuring the storage and self-thinning of mucin have been proved. ... | ['Bacteria', 'Candida', 'Humans', 'Intestinal Mucosa', 'Intestine, Large', 'Isotonic Solutions', 'Mucins', 'Specimen Handling', 'Time Factors'] | 12,630,356 | [['B03'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124.526', 'A03.556.249.249'], ['D26.776.498'], ['D12.776.395.560.631'], ['E01.370.225.998', 'E05.200.998'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Binding site of ribosomal proteins on prokaryotic 5S ribonucleic acids: a study with ribonucleases. | The binding sites of ribosomal proteins L18 and L25 on 5S RNA from Escherichia coli were probed with ribonucleases A, T1, and T2 and a double helix specific cobra venom endonuclease. The results for the protein-RNA complexes, which were compared with those for the free RNA [Douthwaite, S., & Garrett, R. A. (1981) Bioch... | ['Bacterial Proteins', 'Binding Sites', 'Escherichia coli', 'Geobacillus stearothermophilus', 'Nucleic Acid Conformation', 'RNA, Bacterial', 'Ribonucleases', 'Ribosomal Proteins'] | 6,178,424 | [['D12.776.097'], ['G02.111.570.120'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B03.300.390.400.158.400.400', 'B03.353.500.100.400.400', 'B03.510.100.100.400.400', 'B03.510.415.400.158.400.400', 'B03.510.460.410.158.400.400'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.735.473'], ['D08.811.277.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Isolation of bothrasperin, a disintegrin with potent platelet aggregation inhibitory activity, from the venom of the snake Bothrops asper. | The venom of Bothrops asper induces severe coagulation disturbances in accidentally envenomed humans. However, only few studies have been conducted to identify components that interact with the hemostatic system in this venom. In the present work, we fractionated B. asper venom in order to investigate the possible pres... | ['Amino Acid Sequence', 'Animals', 'Blood Platelets', 'Bothrops', 'Chromatography', 'Crotalid Venoms', 'Disintegrins', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Molecular Sequence Data', 'Platelet Aggregation Inhibitors'] | 15,162,701 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.833.672.125.937.240.375'], ['E05.196.181'], ['D20.888.850.960.200', 'D23.946.833.850.960.200'], ['D12.644.138'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Persistence of apoptosis and inflammatory responses in the heart and bone marrow of mice following whole-body exposure to ²⁸Silicon (²⁸Si) ions. | It has been well established that the bone marrow (BM) is a radiosensitive tissue, but the radiosensitivity of the heart is poorly understood. In this study, we investigated the comparative effects of ²⁸Silicon (²⁸Si) ions (one type of heavy ion found in space) on tissue from the heart and the BM of exposed mice. We ga... | ['Animals', 'Apoptosis', 'Bone Marrow', 'Cytokines', 'Heart', 'Inflammation', 'Male', 'Mice', 'Mice, Inbred CBA', 'Myocardium', 'NF-kappa B', 'Poly (ADP-Ribose) Polymerase-1', 'Poly(ADP-ribose) Polymerases', 'Radioisotopes', 'Silicon', 'Whole-Body Irradiation'] | 23,756,637 | [['B01.050'], ['G04.146.954.035'], ['A15.382.216'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A07.541'], ['C23.550.470'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.440', 'B01.050.150.900.649.313.992.635.505.500.400.440'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Raised Proinflammatory Cytokine Production Within Cerebrospinal Fluid Precedes Fever Onset in Patients With Neurosurgery-Associated Bacterial Meningitis. | OBJECTIVE: The objective of the present study was to determine whether selective inflammatory cytokine concentrations within cerebrospinal fluid are useful markers for the differential diagnosis of aseptic and bacterial meningitis within neurosurgical patients.DESIGN: Prospective, open-label, observational, cohort stud... | ['Adult', 'Aged', 'Area Under Curve', 'Calcitonin', 'Calcitonin Gene-Related Peptide', 'Cohort Studies', 'Cytokines', 'Diagnosis, Differential', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Fever', 'Humans', 'Inflammation Mediators', 'Interleukin-6', 'Interleukin-8', 'Male', 'Meningitis, Aseptic', 'Meningitis, Bacte... | 26,196,350 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['D12.644.400.097', 'D12.776.631.650.097'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.85... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of 3-methylcholanthrene on the redox-state of liver and red muscles in vivo. | It was observed, that following an injection of 3-methylcholanthrene (MC), the tissue redox-state potential is modified expressively both in liver and in red muscles. In the liver in the first day an oxidosis develops, which is followed by redosis, but in the muscle a redosis can be observed already in the first day. I... | ['Animals', 'Liver', 'Methylcholanthrene', 'Muscles', 'Oxidation-Reduction', 'Potentiometry', 'Rats'] | 1,927,540 | [['B01.050'], ['A03.620'], ['D02.455.426.559.847.149.500', 'D04.615.149.500'], ['A02.633', 'A10.690'], ['G02.700', 'G03.295.531'], ['E05.196.922.750', 'E05.301.710'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term oral intake of aluminium or zinc does not accelerate Alzheimer pathology in AâPP and AâPP/tau transgenic mice. | Whether or not the oral intake of metals such as aluminium (Al) and zinc (Zn) is a risk for Alzheimer's disease (AD) has been a matter of controversy. Lack of AD pathology in patients with Al encephalopathy indicates Al does not cause AD. On the other hand, some epidemiological studies have suggested high Al increases ... | ['Aluminum', 'Alzheimer Disease', 'Animals', 'Brain', 'Disease Models, Animal', 'Drinking Water', 'Immunohistochemistry', 'Mice', 'Mice, Transgenic', 'Zinc'] | 22,118,300 | [['D01.268.557.050', 'D01.552.547.050'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['B01.050'], ['A08.186.211'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D01.045.250.875.300', 'D01.248.497.158.459.650.300', 'D01.650.550.925.199', 'G07.203.100.418', 'J02.200.418'], ['E01.370.225.500.607.512'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Functional MRI of the cortical sensorimotor system in patients with hereditary spastic paraplegia. | OBJECTIVES: The study aimed to use functional magnetic resonance imaging to ascertain changes in sensorimotor system function in patients with hereditary spastic paraplegia and to correlate it with severity of spasticity and paresis.SETTING: Tartu University Hospital, Tartu, Estonia.METHODS: Nine patients with autosoma... | ['Adult', 'Aged', 'Cerebellum', 'Cerebral Cortex', 'Databases, Factual', 'Female', 'Functional Laterality', 'Hand', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Motor Cortex', 'Movement', 'Somatosensory Cortex', 'Spastic Paraplegia, Hereditary', 'Young Adult'] | 22,751,186 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211.132.810.428.200'], ['A08.186.211.200.885.287.500'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['F02.830.297.425', 'G11.561.225.425'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['M01.060.1... | ['Named Groups [M]', 'Anatomy [A]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
A mortality prediction rule for non-elderly patients with community-acquired pneumonia. | BACKGROUND: No mortality prediction rule is suited for non-elderly patients with community-acquired pneumonia. Therefore, we tried to create a mortality prediction rule that is simple and suitable for non-elderly patients with community-acquired pneumonia.METHODS: Because of low mortality at young age, we used informat... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Age Factors', 'Community-Acquired Infections', 'Comorbidity', 'Confusion', 'Decision Support Techniques', 'Feeding Behavior', 'Female', 'Hospital Mortality', 'Hospitalization', 'Humans', 'Hypotension', 'Japan', 'Male', 'Middle Aged', 'Neoplasms', 'Pneumonia', 'Regr... | 26,956,147 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C01.234'], ['N05.715.350.225', 'N06.850.490.687'], ['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['E05.245', 'L01.313.500.750.190'], ['F01.145.113.547', 'F0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Allosteric modulation of nucleoporin assemblies by intrinsically disordered regions. | Intrinsically disordered regions (IDRs) of proteins are implicated in key macromolecular interactions. However, the molecular forces underlying IDR function within multicomponent assemblies remain elusive. By combining thermodynamic and structural data, we have discovered an allostery-based mechanism regulating the sol... | ['Allosteric Regulation', 'Intrinsically Disordered Proteins', 'Membrane Transport Proteins', 'Multiprotein Complexes', 'Nuclear Pore', 'Nuclear Pore Complex Proteins', 'Protein Domains', 'Receptors, Cytoplasmic and Nuclear', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 31,807,700 | [['G02.111.044'], ['D12.776.481'], ['D12.776.157.530', 'D12.776.543.585'], ['D05.500'], ['A11.284.430.106.279.692.630'], ['D12.776.157.530.750.625', 'D12.776.543.585.750.625'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['D12.776.826'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease. | OBJECTIVES: Fibrosis is a predominant feature of IgG4-related disease (IgG4-RD). B-cell depletion induces a prompt clinical and immunological response in patients with IgG4-RD, but the effects of this intervention on fibrosis in IgG4-RD are unknown. We used the enhanced liver fibrosis (ELF) score to address the impact ... | ['Adult', 'Autoimmune Diseases', 'B-Lymphocytes', 'Biopsy', 'Disease Progression', 'Female', 'Fibrosis', 'Humans', 'Immunity, Cellular', 'Immunoglobulin G', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Myofibroblasts'] | 25,143,523 | [['M01.060.116'], ['C20.111'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C23.550.291.656'], ['C2... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Pharmacotherapeutic effects of toki-shakuyaku-san on leukorrhagia in young women. | Toki-shakuyaku-san is a traditional Chinese herbal prescriptions that is composed of 6 herbal plants, i.e., peony root, atractylodes lancea rhizome, alisma rhizome, hoelen, cnidium rhizome and Japanese angelica root. Administration with Toki-shakuyaku-san normalized irregular menstrual cycle, healed cervical pseudo-ero... | ['Adult', 'Drug Synergism', 'Female', 'Humans', 'Leukorrhea', 'Luteal Phase', 'Menstrual Cycle', 'Plant Extracts', 'Progesterone', 'Uterine Cervical Erosion'] | 8,874,673 | [['M01.060.116'], ['G07.690.773.968.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.894.700.500'], ['G08.686.605.410'], ['G08.686.605'], ['D20.215.784.500', 'D26.667'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['C13.351.500.852.593.112']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
General base and general acid catalyzed intramolecular aminolysis of esters. Cyclization of esters of 2-aminomethylbenzoic acid to phthalimidine. | Plots of log k(0) vs pH for the cyclization of trifluoroethyl and phenyl 2-aminomethylbenzoate to phthalimidine at 30 degrees C in H(2)O are linear with slopes of 1.0 at pH >3. The values of the second-order rate constants k(OH) for apparent OH(-) catalysis in the cyclization reactions are 1.7 x 10(5) and 5.7 x 10(7) M... | ['Buffers', 'Catalysis', 'Esters', 'Indicators and Reagents', 'Kinetics', 'Phthalimides'] | 10,864,739 | [['D27.720.470.280'], ['G02.130'], ['D02.241.400'], ['D27.720.470.410'], ['G01.374.661', 'G02.111.490'], ['D02.241.223.805.810', 'D02.478.600', 'D03.633.100.513.750']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Autoantibodies against protective molecules--C1q, C-reactive protein, serum amyloid P, mannose-binding lectin, and apolipoprotein A1: prevalence in systemic lupus erythematosus. | Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of several autoantibodies. Among the multiple factors involved in SLE development, apoptotic defects and impaired clearance of cellular debris have gained considerable interest, as they contribute to autoantigen overload. Severa... | ['Apolipoprotein A-I', 'Apoptosis', 'Autoantibodies', 'Autoantigens', 'C-Reactive Protein', 'Complement C1q', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Lupus Erythematosus, Systemic', 'Mannose-Binding Lectins', 'Serum Amyloid P-Component'] | 17,899,624 | [['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['G04.146.954.035'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.050.422'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D12.776.124.486.274.050.270'], ['E05.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcription of a silkworm tRNA(cAla) gene is directed by two AT-rich upstream sequence elements. | A region within 35 nucleotides upstream of the transcription initiation site of a variety of silkworm Class III templates is absolutely required for transcription in vitro. To determine whether the activity of this region can be attributed to a particular sequence element, we systematically replaced 4-5 bp segments of ... | ['Animals', 'Base Composition', 'Base Sequence', 'Bombyx', 'Cloning, Molecular', 'DNA', 'Humans', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Promoter Regions, Genetic', 'RNA, Transfer, Ala', 'Transcription, Genetic'] | 8,290,347 | [['B01.050'], ['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['E05.393.220'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Support for a linear length-tension relation of the torso extensor muscles: an investigation of the length and velocity EMG-force relationships. | This study investigated the hypothesis that the length-tension relation of the torso erectors would be linear, mirroring the observed linear increase in extension strength capability toward full flexion. The effect of torso extension velocity on the tension capability of these muscles was also investigated for common m... | ['Abdominal Muscles', 'Adult', 'Back', 'Biomechanical Phenomena', 'Electromyography', 'Humans', 'Least-Squares Analysis', 'Lifting', 'Low Back Pain', 'Lumbar Vertebrae', 'Male', 'Models, Biological', 'Movement', 'Muscle Contraction', 'Muscle, Skeletal', 'Posture', 'Rectus Abdominis', 'Reproducibility of Results', 'Stre... | 8,945,658 | [['A02.633.567.050'], ['M01.060.116'], ['A01.923.176'], ['G01.154.090', 'G01.374.089'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ['G01.374.669'], ['C23.888.592.612.107.400'], ['A02.835.232.834.... | ['Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The emotionally competent leader. | Aristotle once challenged man "to be angry with the right person, to the right degree, at the right time, for the right purpose, and in the right way" (The Nicomachean Ethics). Daniel Goleman, Ph.D., a journalist for the New York Times, expands on this statement in his new book, "Emotional Intelligence." He defines emo... | ['Administrative Personnel', 'Emotions', 'Empathy', 'Humans', 'Interprofessional Relations', 'Leadership', 'Organizational Culture', 'Personnel Management', 'United States', 'Workplace'] | 10,177,113 | [['M01.526.070'], ['F01.470'], ['F01.752.355', 'F01.752.543.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['F01.752.609'], ['N04.452.606'], ['N04.452.677'], ['Z01.107.567.875'], ['N01.824.245.925', 'N04.452.677.975']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Clinical methods in ambulatory major surgery]. | A clinical method is an assistance plan which may be applied to patients suffering from certain determined pathologies and who have a predictable clinical care plan. Its implementation as a working method, in harmony with new trends in our profession on a world-wide scale, was initiated in the John XXIII University Hos... | ['Ambulatory Surgical Procedures', 'Humans', 'Nursing', 'Postoperative Care'] | 16,875,364 | [['E04.030'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.478', 'N04.452.758.377'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Diagnostic imaging of injuries caused by venomous and traumatogenic catfish. | Injuries caused by fish are common in marine and freshwater environments. Catfish of the Ariidae and Pimelodidae families cause about 80% of those injuries. One of the complications of injuries caused by fish is the retention of fragments of the stinger in the wounds. Here we report five cases (of a total of 127 injuri... | ['Animals', 'Bites and Stings', 'Brazil', 'Catfishes', 'Fish Venoms', 'Humans'] | 27,598,647 | [['B01.050'], ['C25.723.127', 'C26.176'], ['Z01.107.757.176'], ['B01.050.150.900.493.080'], ['D20.888.370', 'D23.946.580.370', 'D23.946.833.370'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Delayed initiation but not gradual advancement of enteral formula feeding reduces the incidence of necrotizing enterocolitis (NEC) in preterm pigs. | Enteral formula feeding is a risk factor for necrotizing enterocolitis (NEC) in premature infants, yet studies are conflicting regarding the safest timing for introduction and advancement of feeds. Our aim was to test the effects of early vs. late initiation and abrupt vs. gradual advancement of enteral feeding of an i... | ['Animals', 'Enteral Nutrition', 'Enterocolitis, Necrotizing', 'Gene Expression', 'Ileum', 'Incidence', 'Intestines', 'Parenteral Nutrition, Total', 'Premature Birth', 'Swine'] | 25,238,061 | [['B01.050'], ['E02.421.360', 'E02.642.500.360'], ['C06.405.205.596.700', 'C06.405.469.363.700'], ['G05.297'], ['A03.556.124.684.249', 'A03.556.249.124'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['A03.556.124'], ['E02.421.505.575', 'E02.642.500.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of measured and estimated angles of table tilt at Caesarean section. | BACKGROUND: Lateral maternal tilt reduces aortocaval compression and the consequent cardiovascular instability.METHODS: We measured the angle of table tilt used by 16 anaesthetists during uncomplicated, elective Caesarean section. After initiating anaesthesia, they were asked to position the patient and estimate the an... | ['Anesthesia, Obstetrical', 'Cesarean Section', 'Clinical Competence', 'Female', 'Humans', 'Intraoperative Care', 'Pregnancy', 'Surgical Equipment'] | 12,488,385 | [['E03.155.364'], ['E04.520.252.500'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400'], ['G08.686.784.769'], ['E07.858']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Clinical profile of 93 cases of 46, XY disorders of sexual development in a referral center. | The term DSD refers to disorders that affect the normal process of sexual development causing disagreement between chromosomal, gonadal and phenotypic sex, and this study aimed to describe the clinical profile of a group with DSD 46, XY joined on DSD Clinic of Hospital of Salvador, Bahia Clinics. It was a retrospective... | ['Adolescent', 'Adult', 'Age Factors', 'Brazil', 'Child', 'Child, Preschool', 'Disorder of Sex Development, 46,XY', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Medical Records', 'Retrospective Studies', 'Sex Distribution', 'Sex Factors', 'Tertiary Care Centers', 'Young Adult'] | 26,689,524 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.107.757.176'], ['M01.060.406'], ['M01.060.406.448'], ['C12.706.316.096', 'C13.351.875.253.096', 'C16.131.939.316.096', 'C19.391.119.096'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.308... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Psychiatric treatment and record organized by objectives. | The Weed system is an orderly identification of patient problems, interventions guided by these problems, an systematic documentation of more or less effective solutions. We outline our attempts to modify this system in a manner to retain these essentials while increasing acceptance by staff in a psychiatric unit of a ... | ['Humans', 'Medical Records', 'Medical Records, Problem-Oriented', 'Mental Disorders', 'Psychological Tests'] | 6,969,257 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968', 'N04.452.859.564', 'N05.715.360.300.715.500', 'N06.850.520.308.940.968'], ['E05.318.308.940.968.550', 'N04.452.859.564.600', 'N05.715.360.300.715.500.520', 'N06.850.520.308.940.968.550'], ['F03'], ['F04.711']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Repeated cobalt and chromium ion measurements in patients with bilateral large-diameter head metal-on-metal ReCap-M2A-Magnum total hip replacement. | Background and purpose - Whole-blood (WB) chromium (Cr) and cobalt (Co) measurements are vital in the follow-up of metal-on-metal total hip replacement (MoM THR) patients. We examined whether there is a substantial change in repeated WB, Co, and Cr levels in patients with bilateral ReCap-M2A-Magnum THR. We also specifi... | ['Arthroplasty, Replacement, Hip', 'Chromium', 'Cobalt', 'Female', 'Hip Prosthesis', 'Humans', 'Male', 'Metal-on-Metal Joint Prostheses', 'Middle Aged', 'Time Factors'] | 32,285,731 | [['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400.705'], ['M01.060.116.630'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ethical and legal issues in end-of-life care. | The doctor has a responsibility to develop and maintain an effective approach to ethical decision making and the skills to implement the correct moral action. At the heart of this process is the experience and knowledge of particular conditions and their outcomes, alongside excellence in communication skills and workin... | ['Decision Making', 'Dehydration', 'Ethics, Medical', 'Humans', 'Hypnotics and Sedatives', 'Nutritional Support', 'Palliative Care', 'Personal Autonomy', 'Terminal Care'] | 20,726,464 | [['F02.463.785.373'], ['C18.452.950.179', 'C23.550.274'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['E02.642.500'], ['E02.760.666', 'N02.421.585.666'], ['F02.600', 'I01.880.604.473.380.500', 'K01.752.566.... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[Precapillary pulmonary hypertension: effect of Captopril]. | The immediate and sustained haemodynamic effects of Captopril (CPT), an oral inhibitor of angiotensin converting enzyme, were studied in six patients (pts) with severe pulmonary hypertension (PH) (pulmonary artery pressure: mean +/- SD value = 57 +/- 20 mmHg). Two pts had primary PH, 2 embolic PH and 2 Eisenmenger Phys... | ['Adolescent', 'Adult', 'Captopril', 'Cardiac Output', 'Female', 'Heart Rate', 'Hemodynamics', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Middle Aged', 'Proline', 'Vascular Resistance'] | 6,761,221 | [['M01.060.057'], ['M01.060.116'], ['D12.125.072.401.623.270'], ['E01.370.370.380.150', 'G09.330.380.124'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.116.630'], ['D12.125.072.401.623'], ['G09.330.380.921']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of isoprenoid involved in the post-translational modification of mammalian cell proteins. | Mammalian cell proteins, modified post-translationally by derivatives of [3H]mevalonic acid, were subjected to methylation and sulfonium salt cleavage reactions previously used to release isoprenoids from cysteine residues in yeast peptides. The labeled isoprenoid extracted into chloroform comigrated with farnesol thro... | ['Animals', 'Cell Line', 'Electrophoresis, Polyacrylamide Gel', 'Farnesol', 'Leukemia, Erythroblastic, Acute', 'Mevalonic Acid', 'Mice', 'Neoplasm Proteins', 'Protein Processing, Post-Translational'] | 2,808,372 | [['B01.050'], ['A11.251.210'], ['E05.196.401.402', 'E05.301.300.319'], ['D02.033.415.400', 'D02.455.849.765.424', 'D10.289.400'], ['C04.557.337.539.275.325', 'C15.378.190.636.276'], ['D02.241.511.579'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.624'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative analysis of static sitting posture in chronic stroke. | Unsupported sitting requires postural stability of the trunk which is also necessary for almost all activities in daily living, yet there is a lack of research dealing with the persistence of trunk impairment post-stroke using quantitative methodologies. Therefore, the purpose of this study was to investigate unsupport... | ['Abdomen', 'Case-Control Studies', 'Feedback', 'Female', 'Humans', 'Male', 'Middle Aged', 'Posture', 'Proprioception', 'Stroke', 'Thorax'] | 20,399,661 | [['A01.923.047'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['L01.906.394.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G11.427.695'], ['F02.830.816.541', 'G07.888.750', 'G11.561.790.541'], ['C10.228.140.300.775', 'C14.907.253.855'], ['A01.923.761']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
A risk score to predict ischemic lesions after protected carotid artery stenting. | BACKGROUND AND PURPOSE: While carotid artery stenting can be performed safely in many patients, some have a higher risk for periprocedural complications. The detection of embolic lesions after CAS with DWI could become a useful means to identify these patients. The aim of this study was to determine risk factors for ne... | ['Aged', 'Brain Ischemia', 'Carotid Stenosis', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Functional Laterality', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'ROC Curve', 'Retrospective Studies', 'Risk Assessment', 'Stents'] | 18,692,206 | [['M01.060.116.100'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['E01.370.350.825.500.150'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Loss of desmin triggers mechanosensitivity and up-regulation of Ankrd1 expression through Akt-NF-êB signaling pathway in smooth muscle cells. | Muscle cells, including human airway smooth muscle cells (HASMCs) express ankyrin repeat protein 1 (Ankrd1), a member of ankyrin repeat protein family. Ankrd1 efficiently interacts with the type III intermediate filament desmin. Our earlier study showed that desmin is an intracellular load-bearing protein that influenc... | ['Base Sequence', 'Cells, Cultured', 'DNA Primers', 'Desmin', 'Gene Knockdown Techniques', 'Humans', 'I-kappa B Kinase', 'I-kappa B Proteins', 'Mechanotransduction, Cellular', 'Models, Biological', 'Muscle Proteins', 'Mutagenesis, Site-Directed', 'Myocytes, Smooth Muscle', 'NF-KappaB Inhibitor alpha', 'NF-kappa B', 'Nu... | 22,085,644 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D05.750.078.593.200', 'D12.776.220.475.200'], ['E05.393.335.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D12.776.476.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rheumatic fever prophylaxis: Gisborne experience. | There were 300 admissions to the Cook Hospital with rheumatic fever in 1958-83. During 1958-73 oral penicillin was used for secondary prophylaxis and 77 (35%) of 223 admissions were recurrences. From 1974-83 when parenteral benzathine penicillin was increasingly used there were 77 admissions of which 14 (18%) were read... | ['Administration, Oral', 'Child', 'Drug Combinations', 'Humans', 'Injections, Intramuscular', 'New Zealand', 'Penicillin G', 'Penicillin G Benzathine', 'Penicillin G Procaine', 'Recurrence', 'Rheumatic Fever'] | 6,592,479 | [['E02.319.267.100'], ['M01.060.406'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.460'], ['Z01.639.760.747', 'Z01.678.100.747'], ['D02.065.589.099.750.750', 'D02.886.108.750.750', 'D03.633.100.300.750.750'], ['D02.065.589.099.750.750.685', 'D02.886.108.750.750.685', 'D03.633.100.300... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Suprasellar mass mimicking a hypothalamic glioma in a patient with a complete PROP1 deletion. | Mutations in PROP1 are the most frequent defect detected in patients with combined pituitary hormone deficiency (MIM #262600), characterized by a clinical phenotype of proportionate growth deficit due to impaired production of growth hormone in combination with deficiency of one or more of the additional anterior pitui... | ['Chromosomes, Human, Pair 5', 'Comparative Genomic Hybridization', 'Diagnosis, Differential', 'Female', 'Gene Order', 'Glioma', 'Homeodomain Proteins', 'Homozygote', 'Humans', 'Hypothalamic Neoplasms', 'Infant', 'Magnetic Resonance Imaging', 'Pedigree', 'Pituitary Gland', 'Radiography', 'Sequence Deletion'] | 23,831,233 | [['A11.284.187.520.300.280.290', 'G05.360.162.520.300.280.290'], ['E05.393.285.240', 'E05.393.520.500', 'E05.393.661.187'], ['E01.171'], ['G05.340'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['D12.776.260.400'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C0... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Variation between Ethiopian and North American barley varieties (Hordeum vulgare) in response to Russian wheat aphid (Diuraphis noxia) populations. | The Russian wheat aphid, Diuraphis noxia (Mordvilko) (Hemiptera: Aphididae), causes severe damage to barley, Hordeum vulgare L. (Poales: Poaceae), in the highlands of Ethiopia. Little information is available on the control of this pest in Ethiopia. An experiment aimed at evaluating the resistance of barley varieties f... | ['Animals', 'Aphids', 'Feeding Behavior', 'Food Chain', 'Hordeum', 'Plant Leaves', 'Random Allocation'] | 25,373,187 | [['B01.050'], ['B01.050.500.131.617.412.165'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['G16.500.275.157.250', 'N06.230.124.250'], ['B01.650.940.800.575.912.250.822.481'], ['A18.024.812'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A multivariate analysis of objective voice changes after thyroidectomy without laryngeal nerve injury. | OBJECTIVE: To evaluate the impact of thyroidectomy and the possible effects of factors such as patient sex, operation type, and surgeon experience on objective voice parameters of patients undergoing thyroidectomy without laryngeal nerve injury.DESIGN: Prospective study.SETTING: University hospital.PATIENTS: Thirty-six... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Humans', 'Laryngeal Nerve Injuries', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Prospective Studies', 'Speech Production Measurement', 'Thyroidectomy', 'Voice Disorders', 'Voice Quality'] | 18,559,725 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.360.424', 'C09.400.424', 'C10.292.200.937.750', 'C10.900.300.218.887.750', 'C26.915.300.400.912.750'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E05.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Higher vessel densities in retinoblastoma with local invasive growth and metastasis. | In this study, the importance of angiogenesis (the growth of new blood vessels from existing ones) for the growth of retinoblastoma was investigated by a retrospective immunohistochemical analysis. An individual vessel index for each tumor was determined using the endothelial-specific antibody CD 31 for vessel staining... | ['Endothelium, Vascular', 'Humans', 'Immunohistochemistry', 'Infant', 'Neoplasm Invasiveness', 'Neovascularization, Pathologic', 'Platelet Endothelial Cell Adhesion Molecule-1', 'Retinal Neoplasms', 'Retinoblastoma', 'Retrospective Studies'] | 14,742,245 | [['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.5... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessment of potential application of binary mixtures of 2,4-d with novel aminophosphonates. | A series of new aminoalkane- and aminofluorenephosphonates was synthesized for agrochemical application. The particular compounds had different alkyl substituents at the carbon, nitrogen and phosphorus atoms. Their pesticidal activity was checked by applying various experimental methods. These included the measurements... | ['2,4-Dichlorophenoxyacetic Acid', 'Cucumis sativus', 'Drug Combinations', 'Fluorenes', 'Hemolysis', 'Herbicides', 'Humans', 'Organophosphonates', 'Pesticides', 'Propylamines'] | 16,042,343 | [['D02.241.081.018.386.682.224', 'D02.241.511.316.682.149'], ['B01.650.940.800.575.912.250.300.188.666'], ['D26.310'], ['D02.455.426.559.847.389', 'D04.615.389'], ['C23.550.403', 'G12.122.545'], ['D27.720.031.700.366', 'D27.888.723.366'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.705.429'], ['D27.720.031.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychiatric inpatient care at a county hospital before and after the inception of a university-affiliated psychiatry residency program. | OBJECTIVE: The University of California, Los Angeles (UCLA), along with Kern Medical Center (KMC) and Kern County Mental Health (KCMH), established a new psychiatry residency program in 2004. In this study, we compared psychiatric care at a county psychiatric facility serving a population of 760,000 inhabitants before ... | ['Adult', 'Attitude to Health', 'California', 'Delivery of Health Care', 'Female', 'Health Services Misuse', 'Hospitalization', 'Hospitals, County', 'Humans', 'Internship and Residency', 'Length of Stay', 'Male', 'Medical Indigency', 'Mental Disorders', 'Organizational Affiliation', 'Outcome Assessment, Health Care', '... | 17,890,985 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N04.590.374', 'N05.300'], ['N02.421.380', 'N05.300.150.395'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421.510.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Qinanmer, a new compound from Chinese agarwood 'Qi-Nan' originating from Aquilaria sinensis. | Qinanmer (1), a new compound comprising 2-(2-phenylethyl)chromone and sesquiterpene moieties, together with two known 2-(2-phenylethyl)chromone derivatives (2-3), was isolated from the high-quality Chinese agarwood "Qi-Nan" originating from Aquilaria sinensis (Lour.) Glig. The structure of 1 was elucidated by spectrosc... | ['Cholinesterase Inhibitors', 'Chromones', 'Drugs, Chinese Herbal', 'Flavonoids', 'Molecular Structure', 'Sesquiterpenes', 'Thymelaeaceae', 'Wood'] | 28,043,172 | [['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['D03.383.663.283.266', 'D03.633.100.150.266'], ['D20.215.784.500.350', 'D26.335'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G02.111.570', 'G02.466'], ['D02.455.849.765'], ['B01.650.940.800.575.912.250.932'], ['A18.450.500.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Cyclometalated iridium(III)-â-carboline complexes as potent autophagy-inducing agents. | Two cyclometalated Ir(III)-â-carboline complexes were identified as potent inducers of autophagic cell death. Autophagy induced by these complexes is ROS-mediated and caspase-independent. | ['Alkaloids', 'Autophagy', 'Carbolines', 'Cell Line', 'Humans', 'Iridium', 'Ligands', 'Organometallic Compounds'] | 24,728,495 | [['D03.132'], ['G04.011'], ['D03.383.725.150', 'D03.633.100.473.155', 'D03.633.300.154'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.401', 'D01.268.956.280', 'D01.552.544.401'], ['D27.720.470.480'], ['D02.691']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiplexing Visual Signals in the Suprachiasmatic Nuclei. | The suprachiasmatic nuclei (SCN), the site of the mammalian circadian (daily) pacemaker, contains thousands of interconnected neurons, some of which receive direct retinal input. Here, we study the fast (<1 s) responses of SCN neurons to visual stimuli with a large-scale mathematical model tracking the ionic currents a... | ['Models, Theoretical', 'Photic Stimulation', 'Receptors, GABA-A', 'Suprachiasmatic Nucleus', 'gamma-Aminobutyric Acid'] | 29,117,548 | [['E05.599'], ['E05.723.729'], ['D12.776.157.530.400.175.562', 'D12.776.157.530.400.400.100.100', 'D12.776.543.550.450.175.562', 'D12.776.543.550.450.500.100.100', 'D12.776.543.585.400.175.562', 'D12.776.543.585.400.500.100.100', 'D12.776.543.750.130.500', 'D12.776.543.750.720.200.300.300'], ['A08.186.211.180.497.342.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuroprotective properties of cultured neural progenitor cells are associated with the production of sonic hedgehog. | Numerous studies have shown that abnormal motor behavior improves when neural progenitor cells (NPCs) are transplanted into animal models of neurodegeneration. The mechanisms responsible for this improvement are not fully understood. Indirect anatomical evidence suggests that attention of abnormal motor behavior is att... | ['Animals', 'Antimetabolites', 'Blotting, Western', 'Bromodeoxyuridine', 'Cell Count', 'Cell Survival', 'Cells, Cultured', 'Chick Embryo', 'Culture Media, Conditioned', 'Dopamine', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme-Linked Immunosorbent Assay', 'Epidermal Growth Factor', 'Female', 'Hedgehog Proteins', 'Immu... | 15,749,344 | [['B01.050'], ['D27.505.519.186', 'D27.888.569.042'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.346'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Study on the mechanism and intervention strategy of sunitinib induced nephrotoxicity. | Sunitinib is an oral small molecular tyrosine kinase inhibitor that exhibits potent antiangiogenic and antitumor activity. Unfortunately, sunitinib kidney toxicity limits its clinical use. Renal injury caused by sunitinib treatment can not only lead to the failure of cancer treatment, but also jeopardizes the health an... | ['Apoptosis', 'Cell Line', 'Clinical Trials as Topic', 'Furocoumarins', 'Humans', 'Kidney', 'Male', 'Middle Aged', 'Sunitinib'] | 31,586,633 | [['G04.146.954.035'], ['A11.251.210'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D03.383.663.283.446.794', 'D03.633.100.150.446.794', 'D03.633.300.770'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['M01.060.116.630'], ['D03.383.129.578.823', 'D03.633.100.473... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Autoantibodies to molecular targets in neutrophils in patients with ulcerative colitis. | Autoantibodies against neutrophil granulocytes are frequently observed in patients with ulcerative colitis, but a precise description of the autoantigens involved is lacking. Therefore, sera from 75 patients with ulcerative colitis were studied for antibody specificities by means of indirect immunofluorescence microsco... | ['Autoantibodies', 'Autoantigens', 'Colitis, Ulcerative', 'Cytoplasm', 'Cytosol', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Immunoblotting', 'Immunoglobulin G', 'Lymphocytes', 'Neutrophils'] | 10,063,932 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.050.422'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['A11.284.430.214'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['E05.478.566.350... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Allele-specific and asymmetric polymerase chain reaction amplification in combination: a one step polymerase chain reaction protocol for rapid diagnosis of familial defective apolipoprotein B-100. | We have combined the asymmetric polymerase chain reaction (PCR) with allele-specific PCR to detect a single point mutation. A set of two priming oligonucleotides and a third allele-specific primer were used to identify heterozygotes for a G to A mutation at nucleotide 10,708 in the apolipoprotein B (apo B) gene. The sy... | ['Alleles', 'Apolipoprotein B-100', 'Apolipoproteins B', 'Base Sequence', 'DNA', 'DNA Mutational Analysis', 'Female', 'Humans', 'Hyperlipoproteinemias', 'Male', 'Molecular Sequence Data', 'Nucleic Acid Amplification Techniques', 'Pedigree', 'Polymerase Chain Reaction'] | 1,514,690 | [['G05.360.340.024.340.030'], ['D10.532.091.300.249', 'D12.776.070.400.300.249', 'D12.776.521.120.300.249'], ['D10.532.091.300', 'D12.776.070.400.300', 'D12.776.521.120.300'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['E05.393.760.700.300'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Combined volumetric and surface registration. | In this paper, we propose a novel method for the registration of volumetric images of the brain that optimizes the alignment of both cortical and subcortical structures. In order to achieve this, relevant geometrical information is extracted from a surface-based morph and diffused into the volume using the Navier opera... | ['Algorithms', 'Brain', 'Databases, Factual', 'Elastic Modulus', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Poisson Distribution'] | 19,273,000 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['G01.374.590.605'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['E05.318.740.994.750', 'G17.820.750', 'N05.715.360.750.750.620', 'N06.850.520.830.994.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p. | After a sudden shift to high osmolarity, Saccharomyces cerevisiae cells respond by transiently inducing the expression of stress-protective genes. Msn2p and Msn4p have been described as two transcription factors that determine the extent of this response. In msn2 msn4 mutants, however, many promoters still show a disti... | ['Amino Acid Sequence', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Chaperonins', 'DNA-Binding Proteins', 'Fungal Proteins', 'Gene Expression Regulation, Fungal', 'Genetic Techniques', 'Glycerol', 'Immediate-Early Proteins', 'Mitogen-Activated Protein Kinases', 'Molecular Sequence Data', 'Osmotic Pressure', 'Sacch... | 10,409,737 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['D08.811.277.040.025.142', 'D12.776.580.216.210'], ['D12.776.260'], ['D12.776.354'], ['G05.308.330'], ['E05.393'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D12.776.460', 'D12.776.964.925.968'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The role of Wg signaling in the patterning of embryonic leg primordium in Drosophila. | Cellular interaction between the proximal and distal domains of the limb plays key roles in proximal-distal patterning. In Drosophila, these domains are established in the embryonic leg imaginal disc as a proximal domain expressing escargot, surrounding the Distal-less expressing distal domain in a circular pattern. Th... | ['Animals', 'Body Patterning', 'Drosophila', 'Drosophila Proteins', 'Extremities', 'Genetic Markers', 'Homeodomain Proteins', 'Proto-Oncogene Proteins', 'Signal Transduction', 'Transcription Factors', 'Wings, Animal', 'Wnt1 Protein'] | 12,710,961 | [['B01.050'], ['G07.345.500.100'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['A01.378'], ['D23.101.387', 'G05.695.450'], ['D12.776.260.400'], ['D12.776.624.664.700'], ['G02.111.820', 'G04.835'], ['D12.776.930'], ['A13.395.823'], ['D12.776.467.984.100', 'D12.776.624.664.700.967', 'D23.52... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The possibilities of using fiber optic luminescent light sources in medical-biological studies]. | The use of optical fibers with luminescent spectrum-displacing admixtures inserted into their core enables the prototherapeutic devices to be designed. The paper provides the principle for designing optofiber luminescent light sources. Experiments with laboratory animals and donor blood have indicated that incoherent h... | ['Equipment Design', 'Fiber Optic Technology', 'Humans', 'Luminescent Measurements', 'Optical Fibers', 'Radiography'] | 8,502,147 | [['E05.320'], ['H01.671.617.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.712.516'], ['E07.632.750'], ['E01.370.350.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Retinal and cerebral microvascular signs and diabetes: the age, gene/environment susceptibility-Reykjavik study. | OBJECTIVE: Diabetes increases the risk for microvascular disease. The retina and the brain both have intricate microvascular systems that are developmentally similar. We sought to examine whether microvascular lesions in the retina and in the brain are associated and whether this association differs among people with a... | ['Aged', 'Aged, 80 and over', 'Arterioles', 'Cerebral Hemorrhage', 'Cerebrovascular Circulation', 'Diabetes Mellitus', 'Environment', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Iceland', 'Magnetic Resonance Imaging', 'Male', 'Microcirculation', 'Middle Aged', 'Retina', 'Retinal Vessels', 'Venules'] | 18,332,097 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.015.114.060', 'A07.015.461.080'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['G09.330.100.159'], ['C18.452.394.750', 'C19.246'], ['G16.500.275', 'N06.230'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Psychosocial stressors and the short life spans of legendary jazz musicians. | Mean age at death of 168 legendary jazz musicians and 100 renowned classical musicians were compared to examine whether psychosocial stressors such as severe substance abuse, haphazard working conditions, lack of acceptance of jazz as an art form in the United States, marital and family discord, and a vagabond life sty... | ['Family Relations', 'Humans', 'Life Style', 'Longevity', 'Music', 'Stress, Psychological', 'Substance-Related Disorders', 'United States'] | 10,833,735 | [['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['G07.345.124.519', 'G07.540'], ['K01.602'], ['F01.145.126.990', 'F02.830.900'], ['C25.775', 'F03.900'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Performance Evaluation of G8, a High-Sensitivity Benchtop Preclinical PET/CT Tomograph. | G8 is a benchtop integrated PET/CT scanner dedicated to high-sensitivity and high-resolution imaging of mice. This work characterizes its National Electrical Manufacturers Association NU 4-2008 performance where applicable and also assesses the basic imaging performance of the CT subsystem. Methods: The PET subsystem i... | ['Image Processing, Computer-Assisted', 'Positron Emission Tomography Computed Tomography', 'Scattering, Radiation', 'Signal-To-Noise Ratio'] | 29,903,933 | [['L01.224.308'], ['E01.370.350.350.800.700.500', 'E01.370.350.350.810.645', 'E01.370.350.567.500', 'E01.370.350.600.350.700.810.490', 'E01.370.350.600.350.800.399.500', 'E01.370.350.700.700.810.645', 'E01.370.350.700.810.810.723', 'E01.370.350.710.800.399.500', 'E01.370.350.825.800.399.500', 'E01.370.350.825.810.810.7... | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effective presentation of medical images on an electronic display station. | In summary, the following should be parts of a useful system for electronic medical image display. 1. All display scales should be linearized. 2. Contrast Limited Adaptive Histogram Equalization should be applied to all slices as they arrive at display. 3. A screen or portion thereof should be dedicated to a low-sample... | ['Diagnostic Imaging', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Image Processing, Computer-Assisted', 'Software'] | 3,423,333 | [['E01.370.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.224.308'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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