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Efficacy of metoclopramide as an adjunct to duodenal placement of small-bore feeding tubes: a randomized, placebo-controlled, double-blind study. | We examined whether metoclopramide would improve the success rate of transpyloric intubation of a weighted Corpak feeding tube when fluoroscopic guidance is not used. Seventy patients were randomized in a prospective, double-blind fashion to receive either placebo (n = 35) or metoclopramide, 10 mg (n = 35) parenterally... | ['Adult', 'Aged', 'Clinical Trials as Topic', 'Diabetes Mellitus', 'Double-Blind Method', 'Duodenum', 'Enteral Nutrition', 'Female', 'Humans', 'Intubation, Gastrointestinal', 'Male', 'Metoclopramide', 'Middle Aged', 'Prospective Studies', 'Random Allocation', 'Regression Analysis', 'Stomach'] | 3,102,779 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C18.452.394.750', 'C19.246'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E02.421.360', 'E02.642.500.360'], ['B0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mathematical model of L5178Y mouse lymphoma forward mutation assay. | A mathematical model of the biological protocol for the Mouse Lymphoma L5178Y Forward Mutation Bioassay is presented. The model relates the mutant progenitor frequency (MPF), the number of cells per million surviving cells with DNA damage after exposure to the chemical, to the mutant frequency (MF), the number of TFT-r... | ['Animals', 'Cell Division', 'DNA Repair', 'Leukemia L5178', 'Leukemia, Experimental', 'Mathematics', 'Mice', 'Models, Biological', 'Mutagenicity Tests', 'Mutation', 'Time Factors'] | 6,877,266 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G02.111.222', 'G05.219'], ['C04.557.337.372.602', 'C04.619.531.602'], ['C04.557.337.372', 'C04.619.531', 'E05.598.500.496.500'], ['H01.548'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395'], ['E05.393.560', 'E05.940.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A single amino acid substitution in lactate dehydrogenase improves the catalytic efficiency with an alternative coenzyme. | Using site-directed mutagenesis, the NADH-linked lactate dehydrogenase from Bacillus stearothermophilus has been specifically altered at a single residue to shift the coenzyme specificity towards NADPH. The single change is at position 53 in the amino acid sequence where a conserved aspartate has been replaced by a ser... | ['Amino Acid Sequence', 'Base Sequence', 'Catalysis', 'DNA Mutational Analysis', 'Geobacillus stearothermophilus', 'Kinetics', 'L-Lactate Dehydrogenase', 'Models, Molecular', 'Molecular Sequence Data', 'NAD', 'NADP', 'Structure-Activity Relationship'] | 2,302,233 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.130'], ['E05.393.760.700.300'], ['B03.300.390.400.158.400.400', 'B03.353.500.100.400.400', 'B03.510.100.100.400.400', 'B03.510.415.400.158.400.400', 'B03.510.460.410.158.400.400'], ['G01.374.661', 'G02.111.490'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Linear correlation between rheological, mechanical and mucoadhesive properties of polycarbophil polymer blends for biomedical applications. | Polycarbophil is widely used in a variety of pharmaceutical formulations, mainly for their strong ability to adhere to the epithelial and mucous barriers (bio/mucoadhesion). On the other hand, its association with the thermoresponsive polymer (poloxamer 407) has been poorly explored. This work investigates the rheologi... | ['Acrylic Resins', 'Adhesiveness', 'Materials Testing', 'Poloxamer', 'Rheology'] | 28,219,852 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['G02.860.139'], ['E05.570'], ['D02.033.455.250.700.682', 'D05.750.741.667', 'D25.720.741.667', 'J01.637.051.720.741.667'], ['E05.830', 'H01.671.808']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Characterization of the gene encoding hydroxylamine oxidoreductase in Nitrosomonas europaea. | Hydroxylamine oxidoreductase (HAO) catalyzes the oxidation of hydroxylamine to nitrite in Nitrosomonas europaea. The electrons released in the reaction are partitioned to ammonium monooxygenase and to the respiratory chain. The immediate acceptor of electrons from HAO is believed to be cytochrome c-554 (Cyt c-554). We ... | ['Amino Acid Sequence', 'Base Sequence', 'Cytochrome c Group', 'Gene Library', 'Genes, Bacterial', 'Molecular Sequence Data', 'Nitrosomonas', 'Oligonucleotide Probes', 'Oxidoreductases', 'Peptide Fragments', 'Sequence Analysis', 'Transcription, Genetic', 'Trypsin'] | 8,288,544 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.244.286', 'D12.776.422.220.286'], ['G05.360.325'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['L01.453.245.667'], ['B03.440.400.425.562.500', 'B03.660.075.550.500'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Serum growth hormone and free fatty acid levels in heifers and cows before, during and after parturition. | A large number of blood samples was taken from the jugular vein of 18 cows or heifers during parturition, especially during stage II. In 9 animals an increase in serum growth hormone was observed and the peak occurred within the period which began when the forelegs of the calf became visible in the vulva, and ended a f... | ['Animals', 'Cattle', 'Fatty Acids, Nonesterified', 'Female', 'Growth Hormone', 'Labor, Obstetric', 'Pregnancy', 'Pregnancy, Animal'] | 1,034,460 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D10.251.310'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['G08.686.784.769.326'], ['G08.686.784.769'], ['G08.686.784.769.498']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Prenatal ultrasound findings in a case of cystic adenomatoid malformation of the lung with generalized hydrops of the fetus]. | The sonographic findings of polyhydramnion, foetal ascites, generalised hydrops, as well as tumour in the right thoracic or upper abdominal regions are described as an expression of a uniform disease pattern of the foetus. The case under discussion concerns a congenital cystic-adenomatoid malformation of the right lung... | ['Adult', 'Diagnosis, Differential', 'Edema', 'Female', 'Humans', 'Infant, Newborn', 'Lung', 'Placenta', 'Pregnancy', 'Prenatal Diagnosis', 'Ultrasonography'] | 6,394,421 | [['M01.060.116'], ['E01.171'], ['C23.888.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A04.411'], ['A16.710'], ['G08.686.784.769'], ['E01.370.378.630'], ['E01.370.350.850']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Plasma-free homovanillic acid: within- and across-day stability in children and adults with Tourette's syndrome. | Within- and across-day stability of plasma-free homovanillic acid (pHVA) was assessed in children and adults with Tourette's syndrome. A diurnal fall in pHVA was observed in 13 of 15 subjects. There was a small but significant (p less than .0001) decrease (8%) in mean morning pHVA levels obtained just 20 minutes apart ... | ['Adolescent', 'Adult', 'Child', 'Circadian Rhythm', 'Female', 'Homovanillic Acid', 'Humans', 'Male', 'Middle Aged', 'Time Factors', 'Tourette Syndrome'] | 3,473,273 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['G07.180.562.190'], ['D02.241.223.601.521'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G01.910.857'], ['C10.228.140.079.898', 'C10.228.662.825.800', 'C10.574.500.850', 'C16.320.400.820', 'F03.625.992.850']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of consultant operative supervision and surgical mortality in Australia. | BACKGROUND: In this study, the Australian and New Zealand Audit of Surgical Mortality evaluated the effect of operative supervision on certain post-operative outcomes in the surgical death subset.METHODS: This retrospective cohort study was based upon mortality data collected in 2009 which included 1673 patients who di... | ['Aged', 'Australia', 'Cohort Studies', 'Consultants', 'Female', 'Humans', 'Male', 'Medical Audit', 'New Zealand', 'Retrospective Studies', 'Surgical Procedures, Operative'] | 23,095,025 | [['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['M01.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.250.500', 'N05.700.175.500'], ['Z01.639.760.747', 'Z01.678.100.747'], ['E05.318.372.500.500.500', 'E05.318.... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy. | The treatment of metastatic castration-resistant prostate cancer (mCRPC) remains challenging with current treatment options. The development of more effective therapies is, therefore, urgently needed. Targeted radionuclide therapy with prostate-specific membrane antigen (PSMA)-targeting ligands has revealed promising c... | ['Animals', 'Antigens, Surface', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Drug Design', 'Drug Stability', 'Female', 'Glutamate Carboxypeptidase II', 'Humans', 'Ligands', 'Lutetium', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Prostatic Neoplasms', 'Radioisotopes', 'Radiopharmaceuticals', 'Serum Albumin, ... | 29,684,274 | [['B01.050'], ['D23.050.301'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E05.916.330'], ['D08.811.277.656.350.245.400', 'D08.811.277.656.350.555.500', 'D08.811.277.656.675.555.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The effect of nitric oxide on acetylcholine release in the rabbit bladder. | We evaluated the effects of nitric oxide (NO) on acetylcholine release and the contractile response induced by electrical field stimulation in rabbit bladder smooth muscles using a muscle bath and high performance liquid chromatography coupled with microdialysis. Electrical field stimulation (supramaximum voltage, puls... | ['Acetylcholine', 'Animals', 'Arginine', 'Atropine', 'Electric Stimulation', 'Enzyme Inhibitors', 'Female', 'In Vitro Techniques', 'Microdialysis', 'Muscarinic Antagonists', 'Muscle Contraction', 'Muscle, Smooth', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitroprusside', 'Potassium Chloride', 'Rabbits', 'Urinary Bladde... | 11,779,038 | [['D02.092.211.111'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['E05.723.402'], ['D27.505.519.389'], ['E05.481'], ['E05.196.353.500'], ['D27.505.519.625... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Texture and moments-based classification of the acrosome integrity of boar spermatozoa images. | The automated assessment of the sperm quality is an important challenge in the veterinary field. In this paper, we explore how to describe the acrosomes of boar spermatozoa using image analysis so that they can be automatically categorized as intact or damaged. Our proposal aims at characterizing the acrosomes by means... | ['Acrosome', 'Animals', 'Male', 'Spermatozoa', 'Swine'] | 22,382,003 | [['A05.360.490.890.820.100', 'A11.284.430.214.190.875.190.550.040', 'A11.497.760.400.100'], ['B01.050'], ['A05.360.490.890', 'A11.497.760'], ['B01.050.150.900.649.313.500.880']] | ['Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Predictive factors for technical difficulties during retropubic radical prostatectomy using external pelvimetry]. | External pelvimetry can be used to predict the technical difficulty of retropubic radical prostatectomy and the results should be taken into account in the treatment plan. | ['Humans', 'Male', 'Pelvis', 'Prostatectomy'] | 12,108,360 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.600'], ['E04.950.774.860.625']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relationships between blood pressure, heart rate and plasma epinephrine, norepinephrine, angiotensin II concentrations, plasma renin activity during chronic guanfacine therapy in patients with essential arterial hypertension. | The evolution of blood pressure, heart rate, epinephrine, norepinephrine, angiotensin II and plasma renin activity has been studied in 10 patients with essential arterial hypertension before and during a two months period of treatment with guanfacine, a new centrally acting hypotensive drug. Guanfacine was proven effec... | ['Angiotensin II', 'Antihypertensive Agents', 'Blood Pressure', 'Epinephrine', 'Female', 'Guanfacine', 'Guanidines', 'Heart Rate', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Norepinephrine', 'Phenylacetates', 'Renin'] | 3,895,792 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Examining student rating of teaching effectiveness using FACETS. | Students' evaluations of teaching staff can be considered high-stakes, as they are often used to determine promotion, reappointment, and merit pay to academics. Using Facets, the reliability and validity of one student rating questionnaire is analyzed. A total of 13,940 respondents of the Human Science Division of Inte... | ['Employee Performance Appraisal', 'Faculty', 'Humans', 'Students', 'Surveys and Questionnaires'] | 22,089,510 | [['N04.452.677.370'], ['M01.526.702.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.848'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evolution of sfbI encoding streptococcal fibronectin-binding protein I: horizontal genetic transfer and gene mosaic structure. | Streptococcal fibronectin-binding protein is an important virulence factor involved in colonization and invasion of epithelial cells and tissues by Streptococcus pyogenes. In order to investigate the mechanisms involved in the evolution of sfbI, the sfbI genes from 54 strains were sequenced. Thirty-four distinct allele... | ['Adhesins, Bacterial', 'Amino Acid Sequence', 'Base Sequence', 'Blood', 'Consensus Sequence', 'DNA Primers', 'DNA, Bacterial', 'Gene Transfer Techniques', 'Humans', 'Molecular Sequence Data', 'Mosaicism', 'Pharynx', 'Sequence Alignment', 'Skin', 'Streptococcal Infections', 'Streptococcus'] | 14,662,917 | [['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A12.207.152', 'A15.145'], ['G02.111.570.580.175'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.212'], ['E05.393.350']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Serum of 25-Hydroxyvitamin D and Intact Parathyroid Hormone Levels in Postmenopausal Women with Hip and Upper Limb Fractures. | OBJECTIVES: To assess the serum of 25-hydroxyvitamin D (25(OH)D) and intact parathyroid hormone (iPTH) levels in postmenopausal women from northern China with hip and upper limb fractures.DESIGN: Case-control.SETTING: Affiliated Hospital of Qingdao University.PARTICIPANTS: Postmenopausal women diagnosed with hip fractu... | ['Aged', 'Alkaline Phosphatase', 'Arm Injuries', 'Biomarkers', 'Calcium', 'Case-Control Studies', 'China', 'Female', 'Fractures, Bone', 'Hip Fractures', 'Humans', 'Hyperparathyroidism', 'Middle Aged', 'Parathyroid Hormone', 'Phosphorus', 'Postmenopause', 'Risk Factors', 'Surveys and Questionnaires', 'Vitamin D', 'Vitam... | 27,131,061 | [['M01.060.116.100'], ['D08.811.277.352.650.035'], ['C26.088'], ['D23.101'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['Z01.252.474.164'], ['C26.404'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The arterial pattern and fractal dimension of the dog kidney. | A method has been developed by which it is possible to measure the fractal dimension of the arterial tree of the kidney. The objective of this work is to determine a method which permits us to discriminate between the architectures of specific organs by reference to a unique number, namely the fractal dimension of the ... | ['Abdomen', 'Animals', 'Arteries', 'Arterioles', 'Dogs', 'Jugular Veins', 'Kidney', 'Male', 'Models, Biological', 'Plastic Embedding', 'Renal Circulation', 'Software'] | 1,457,978 | [['A01.923.047'], ['B01.050'], ['A07.015.114'], ['A07.015.114.060', 'A07.015.461.080'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.015.908.498'], ['A05.810.453'], ['E05.599.395'], ['E01.370.225.500.620.760.440.640', 'E01.370.225.750.600.760.440.640', 'E05.200.500.620.760.440.640', 'E05.200.750.600.760.440.640']... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Anatomical description of the main vessels for venipuncture in the black-striped capuchin monkey (Sapajus libidinosus, Silva Junior, 2002). | BACKGROUND: The scarcity of data on the anatomy of Sapajus libidinosus has impeded the execution for appropriate veterinary treatment. The objective of this study was to describe the main peripheral veins of the capuchin monkey, used in venipuncture and indicate the best access route for venipuncture procedures.METHODS... | ['Animals', 'Cebinae', 'Female', 'Male', 'Phlebotomy', 'Veins'] | 28,809,436 | [['B01.050'], ['B01.050.150.900.649.313.988.400.600.150.170'], ['E01.370.225.998.110.625', 'E02.800.558', 'E04.665.150.625', 'E05.200.998.110.625'], ['A07.015.908']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cognitive impairment in rheumatoid arthritis. | The objective of this study was to determine the frequency of cognitive impairment in patients with rheumatoid arthritis (RA). A cross-sectional study of 40 patients with RA and 40 healthy controls was performed. To assess cognitive impairment, anxiety and depression, the following standardized psychiatric and clinical... | ['Adult', 'Arthritis, Rheumatoid', 'Cognition Disorders', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales'] | 15,319,812 | [['M01.060.116'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['F03.615.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.513.653']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Salivary cortisol: a predictor of convictions for driving under the influence of alcohol? | AIMS: To examine the relationship between salivary cortisol and frequency of past driving under the influence of alcohol (DUI) convictions.METHODS: A total of 104 males with previous DUI convictions (from one to eight) and mean age of 44.7 years were assessed on measures characterizing repeat DUI offenders, including s... | ['Accidents, Traffic', 'Adult', 'Alcoholic Intoxication', 'Alcoholism', 'Breath Tests', 'Female', 'Humans', 'Hydrocortisone', 'Liver Function Tests', 'Male', 'Middle Aged', 'Prognosis', 'Recurrence', 'Saliva', 'Treatment Failure'] | 15,914,513 | [['N06.850.135.392'], ['M01.060.116'], ['C25.775.100.175', 'F03.900.100.300'], ['C25.775.100.250', 'F03.900.100.350'], ['E01.370.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['E01.370.372.460'], ['M01.060.116.630'], ['E01.... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Multiple compression and plasto-elastic behaviour of paracetamol and microcrystalline cellulose mixtures. | Radial tensile strength, friability, ER/PC (elastic recovery/plastic compression) ratio and energy ratio analyses were evaluated for various mixtures of paracetamol and microcrystalline cellulose (Avicel). A good correlation occurred between the energy ratio and the other variables. Linear relationships were found betw... | ['Acetaminophen', 'Cellulose', 'Chemistry, Pharmaceutical', 'Tablets', 'Tensile Strength'] | 2,907,530 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['H01.158.703.007', 'H01.181.466'], ['D26.255.830'], ['G01.374.850']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
The use of a HEMOCHRON JR. HEMONOX point of care test in monitoring the anticoagulant effects of enoxaparin during interventional coronary procedures. | BACKGROUND: Enoxaparin is increasingly used for the anticoagulation of patients undergoing percutaneous coronary intervention (PCI). Several reports have suggested the utility of using point of care tests in monitoring the anticoagulation levels of enoxaparin in patients undergoing PCI. The objective of this study was ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angioplasty, Balloon, Coronary', 'Anticoagulants', 'Drug Monitoring', 'Enoxaparin', 'Female', 'Humans', 'Male', 'Middle Aged', 'Point-of-Care Systems', 'Whole Blood Coagulation Time'] | 16,622,609 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['D27.505.954.502.119'], ['E01.370.520.200'], ['D09.69... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Conservation and diversification of genes by mismatch correction and SOS induction. | Regulation of genetic stability is discussed in terms of interactions between constitutive and inducible DNA repair processes with specific emphasis on the results of our experimental studies of mismatch correction and SOS induction in Escherichia coli. | ['Base Composition', 'DNA Repair', 'DNA Replication', 'DNA, Bacterial', 'DNA-Directed DNA Polymerase', 'Escherichia coli', 'Genes, Bacterial', 'Mutation'] | 6,814,501 | [['G02.111.080'], ['G02.111.222', 'G05.219'], ['G02.111.225', 'G05.226'], ['D13.444.308.212'], ['D08.811.913.696.445.308.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.365.590']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interleukin-22 and Its Correlation with Disease Activity in Plaque Psoriasis. | Psoriasis is a chronic debilitating skin disease with an estimated prevalence reaching 2% of the worldwide population. Psoriatic disease is driven by a network of complicated reciprocal interactions among innate and adaptive mechanisms of immune system with structural components of the skin. Interleukin (IL)-22 mediate... | ['Adult', 'Aged', 'Cells, Cultured', 'Disease Progression', 'Female', 'Humans', 'Interleukins', 'Keratinocytes', 'Male', 'Middle Aged', 'Psoriasis', 'Skin', 'T-Lymphocytes', 'Up-Regulation'] | 30,291,393 | [['M01.060.116'], ['M01.060.116.100'], ['A11.251'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465', 'D12.776.467.374.465', 'D23.529.374.465'], ['A11.409.500', 'A11.436.397'], ['M01.060.116.630'], ['C17.800.859.675'], ['A17.815'], ['A11.118.637.555.567.569', 'A15.145.229.637... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevalence of obsessive-compulsive disorder in patients with systemic lupus erythematosus. | BACKGROUND: The goal of this pilot study was to investigate the prevalence of obsessive-compulsive disorder (OCD) in a group of patients with systemic lupus erythematosus (SLE).METHOD: Fifty adult patients enrolled in out-patient SLE studies at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (... | ['Adult', 'Aged', 'Comorbidity', 'Diagnostic and Statistical Manual of Mental Disorders', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Obsessive-Compulsive Disorder', 'Prevalence', 'Severity of Illness Index', 'Surveys and Questionnaires'] | 15,096,067 | [['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['L01.453.245.945.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['M01.060.116.630'], ['F03.080.600'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.30... | ['Named Groups [M]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Determinants of Case Fatality After Hospitalization for Stroke in France 2010 to 2015. | Background and Purpose- The aims of this study were to (1) describe early and late case fatality rates after stroke in France, (2) evaluate whether their determinants differed, and (3) analyze time trends between 2010 and 2015. Methods- Data were extracted from the Syst?me National des donn?es de sant? database. Patien... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Antihypertensive Agents', 'Brain Ischemia', 'Cerebral Hemorrhage', 'Comorbidity', 'Databases, Factual', 'Female', 'France', 'Hospital Mortality', 'Hospitalization', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Mortality', 'Prognosis', 'Sex D... | 30,621,528 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.411.162'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['N05.715.350.225', 'N06.850.490.687'], ... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
31P-NMR spectroscopy of human cancer cells proliferating in a basement membrane gel. | We describe a system in which proliferating human breast cancer cells are monitored by NMR spectroscopy for at least 6 days in basement membrane gel (BMG)1 threads. The cells are perfused under standard sterile cell culture conditions. 31P-NMR spectra obtained continuously for up to 64 h showed an increase in the signa... | ['Adenosine Triphosphate', 'Animals', 'Basement Membrane', 'Breast Neoplasms', 'Cell Count', 'Cell Division', 'Gels', 'Glycerylphosphorylcholine', 'Humans', 'Magnetic Resonance Spectroscopy', 'Mice', 'Mice, Nude', 'Phosphates', 'Phosphatidylethanolamines', 'Tumor Cells, Cultured'] | 3,384,239 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A10.272.220', 'A10.615.179'], ['C04.588.180', 'C17.800.090.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D20.280.320',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development and application of a HPLC-ICP-MS method to determine selenium speciation in muscle of pigs treated with different selenium supplements. | Dietary selenium deficiency is recognized as a global problem. Pork is the most widely consumed meat throughout the world and an important source of selenium for humans. In this study, a reliable approach was developed for analyzing selenium and its speciation in the muscles of pigs after different selenium treatments.... | ['Animals', 'Chromatography, High Pressure Liquid', 'Cystine', 'Dietary Supplements', 'Food Analysis', 'Male', 'Mass Spectrometry', 'Muscle, Skeletal', 'Organoselenium Compounds', 'Reproducibility of Results', 'Selenious Acid', 'Selenium', 'Selenium Compounds', 'Selenocysteine', 'Selenomethionine', 'Swine', 'Urea'] | 31,437,711 | [['B01.050'], ['E05.196.181.400.300'], ['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.886.520.150.087', 'D12.125.095.369', 'D12.125.119.369', 'D12.125.166.230.369'], ['G07.203.300.456', 'J02.500.456'], ['E05.362', 'J01.576.423.850.100'], ['E05.196.566'], ['A02.633.567', 'A10.690.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Apocrine carcinoma of the breast--a morphologic comparison of the apocrine sweat glands and the apocrine metaplastic epithelia in mastopathy]. | An operatively removed apocrine carcinoma of the breast from a 62-year-old Japanese lady has been observed by the ABC method, using the monoclonal antibody 115D8. The cancer cells and metaplastic epithelia exhibited similar ultrastructural findings (an apical snout, apocrine granules, etc.) as the apocrine sweat gland ... | ['Antibodies, Monoclonal', 'Apocrine Glands', 'Breast Neoplasms', 'Carcinoma', 'Epithelium', 'Female', 'Humans', 'Immunohistochemistry', 'Membrane Glycoproteins', 'Metaplasia', 'Microscopy, Electron', 'Middle Aged', 'Mucin-1', 'Sweat Gland Neoplasms', 'Sweat Glands'] | 3,398,262 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A10.336.899.206', 'A17.815.830.206'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.5... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Antifouling Lipid Membranes over Protein A for Orientation-Controlled Immunosensing in Undiluted Serum and Plasma. | An important advance in biosensor research is the extension and application of laboratory-developed methodologies toward clinical diagnostics, though the propensity toward nonspecific binding of materials in clinically relevant matrices, such as human blood serum and plasma, frequently leads to compromised assays. Seve... | ['Animals', 'Antibodies, Immobilized', 'Cholera Toxin', 'Gold', 'Humans', 'Immunoassay', 'Immunoglobulin Fab Fragments', 'Immunoglobulin G', 'Membranes, Artificial', 'Mice', 'Phosphatidylcholines', 'Phosphatidylglycerols', 'Proof of Concept Study', 'Staphylococcal Protein A'] | 31,262,175 | [['B01.050'], ['D12.776.124.486.485.114.207', 'D12.776.124.790.651.114.207', 'D12.776.377.715.548.114.207', 'D12.776.463.250'], ['D08.811.913.400.725.115.180', 'D23.946.123.194', 'D23.946.330.150'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Behaving as or behaving as if? Children's conceptions of personified robots and the emergence of a new ontological category. | Imagining another's perspective is an achievement in social cognition and underlies empathic concern and moral regard. Imagination is also within the realm of fantasy, and may take the form of imaginary play in children and imaginative production in adults. Yet, an interesting and provocative question emerges in the ca... | ['Adult', 'Child', 'Child Behavior', 'Child Development', 'Cognition', 'Computer Simulation', 'Computers', 'Empathy', 'Humans', 'Interpersonal Relations', 'Play and Playthings', 'Robotics', 'Social Behavior'] | 20,851,571 | [['M01.060.116'], ['M01.060.406'], ['F01.145.179'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.188'], ['L01.224.160'], ['L01.224.230.260'], ['F01.752.355', 'F01.752.543.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['I03.450.642.693'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.05... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
Delayed complications thirty-six years after hemispherectomy: a case report. | PURPOSE: To describe a late complication of hemispherectomy in a patient in whom symptoms of hydrocephalus developed 36 years after her left-sided hemispherectomy, the longest delay on record.METHODS: Hemispherectomy has been successfully used in the treatment of intractable epilepsy associated with infantile-type hemi... | ['Brain', 'Brain Diseases', 'Epilepsy', 'Female', 'Follow-Up Studies', 'Functional Laterality', 'Hemosiderosis', 'Humans', 'Hydrocephalus', 'Middle Aged', 'Neuropsychological Tests', 'Postoperative Complications', 'Time Factors', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Ventriculoperitoneal Shunt'] | 8,764,815 | [['A08.186.211'], ['C10.228.140'], ['C10.228.140.490'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F02.830.297.425', 'G11.561.225.425'], ['C18.452.565.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602'], ['M01.060.116.630'], ['F04.711.513'], ... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Greek version of the Quality of Life in Epilepsy Inventory (QOLIE-31). | This study is presenting the translation and cultural adaptation into Greek of the Quality of Life in Epilepsy Inventory (QOLIE-31). We adapted the QOLIE-31 to Greek through a procedure of translation-back-translation. Sixty-three patients were interviewed and completed the QOLIE-31 and the GHQ questionnaires. We re-ex... | ['Adolescent', 'Adult', 'Aged', 'Anticonvulsants', 'Epilepsy', 'Female', 'Greece', 'Humans', 'Male', 'Middle Aged', 'Psychometrics', 'Quality of Life', 'Surveys and Questionnaires'] | 16,721,643 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.427.080'], ['C10.228.140.490'], ['Z01.542.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.780'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
In Utero Exposure to Benzo[a]pyrene Induces Ovarian Mutations at Doses That Deplete Ovarian Follicles in Mice. | Polycyclic aromatic hydrocarbons like benzo[a]pyrene (BaP) are ubiquitous environmental contaminants formed during incomplete combustion of organic materials. Our prior work showed that transplacental exposure to BaP depletes ovarian follicles and increases prevalence of epithelial ovarian tumors later in life. We used... | ['Animals', 'Benzo(a)pyrene', 'Environmental Pollutants', 'Female', 'Lac Operon', 'Maternal Exposure', 'Maternal-Fetal Exchange', 'Mice', 'Mutagens', 'Mutation', 'Ovarian Follicle', 'Pregnancy', 'Prenatal Exposure Delayed Effects'] | 30,353,947 | [['B01.050'], ['D02.455.426.559.847.799.306.300', 'D04.615.799.306.300'], ['D27.888.284'], ['G05.360.340.024.686.545', 'G05.360.340.358.207.500.545'], ['N06.850.460.350.145'], ['G08.686.784.769.455'], ['B01.050.150.900.649.313.992.635.505.500'], ['D27.888.569.468'], ['G05.365.590'], ['A05.360.319.114.630.535', 'A06.300... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Domains of p85cdc10 required for function of the fission yeast DSC-1 factor. | p85cdc10 is a component of the S.pombe DSC-1 complex, which is thought to mediate periodic transcription of genes in late G1. In order to understand the role of p85cdc10 in the function of this complex, we have analysed which domains of p85cdc10 are required for biological activity and the formation of a stable DSC-1 c... | ['Base Sequence', 'Cell Cycle Proteins', 'DNA, Fungal', 'Fungal Proteins', 'GTP Phosphohydrolases', 'Kinetics', 'Macromolecular Substances', 'Membrane Proteins', 'Molecular Sequence Data', 'Saccharomyces cerevisiae Proteins', 'Schizosaccharomyces', 'Schizosaccharomyces pombe Proteins', 'Temperature', 'Transcription Fac... | 8,367,276 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.167'], ['D13.444.308.300'], ['D12.776.354'], ['D08.811.277.040.330'], ['G01.374.661', 'G02.111.490'], ['D05'], ['D12.776.543'], ['L01.453.245.667'], ['D12.776.354.750'], ['B01.300.107.797', 'B01.300.930.720'], ['D12.776.354.875'], ['G01.906.595', 'G1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Knowledge and occupational hazards of barbers in the transmission of hepatitis B and C was low in Kumasi, Ghana. | INTRODUCTION: Blood borne viral hepatitis transmission still ranges between 4-20% in many Ghanaian communities. Hepatocellular carcinoma (HCC) also called liver cancer is reported as the leading cause of cancer mortality among males in Ghana. We studied the knowledge and risk factors associated with barbers' occupation... | ['Adolescent', 'Adult', 'Aged', 'Barbering', 'Cross-Sectional Studies', 'Equipment Contamination', 'Ghana', 'Hand Disinfection', 'Health Knowledge, Attitudes, Practice', 'Hepatitis B', 'Hepatitis B Vaccines', 'Hepatitis C', 'Humans', 'Literacy', 'Male', 'Middle Aged', 'Sampling Studies', 'Sterilization', 'Surveys and Q... | 26,161,183 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['J01.576.082'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N06.850.540'], ['Z01.058.290.190.320'], ['N06.850.670.150.500'], ['F01.100.150.500', 'N05.300.150.410'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435',... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Prognostic value of p27(Kip1) and CyclinD1 expression in esophageal cancer. | It has recently been reported that the reduced expression of p27(Kip1) is a negative prognostic marker in several carcinomas. In this study, we examined the expression of p27(Kip1) in esophageal squamous cell carcinomas in order to understand its prognostic role. We also examined the expression of cyclinD1, which is be... | ['Aged', 'Carcinoma, Squamous Cell', 'Cell Cycle Proteins', 'Cyclin D1', 'Cyclin-Dependent Kinase Inhibitor p27', 'Cyclin-Dependent Kinases', 'Esophageal Neoplasms', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Immunohistochemistry', 'Male', 'Microtubule-Associated Proteins', 'Middle Aged', 'Multivari... | 10,575,318 | [['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D12.776.167'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['D12.644.360.225.600', 'D12.776.167.187.600', 'D12.776.476.225.600', 'D12.776.624.776.355.600'], ['D08.811.913.696.620.682... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Intestinal alpha beta T cells differentiate and rearrange antigen receptor genes in situ in the human infant. | Intestinal Ag exposure during neonatal life influences appropriate adult immune responses. To define the mechanisms shaping the T cell repertoire during this period, we examined T cell differentiation and receptor diversity in the intestine of human infants. Developmental phenotypes of intraepithelial and lamina propri... | ['Adolescent', 'Aging', 'Cell Differentiation', 'Child, Preschool', 'Clone Cells', 'Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor', 'Gene Rearrangement, beta-Chain T-Cell Antigen Receptor', 'Humans', 'Immunophenotyping', 'Infant', 'Infant, Newborn', 'Intestinal Mucosa', 'Intestine, Large', 'Intestine, Small',... | 15,585,840 | [['M01.060.057'], ['G07.345.124'], ['G04.152'], ['M01.060.406.448'], ['A11.251.353'], ['G05.344.801.111', 'G12.500.287.111'], ['G05.344.801.211', 'G12.500.287.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['M01.060.703'], ['M01.060.703.520'], ['A0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical significance of occult micrometastases in axillary lymph nodes in "node-negative" breast cancer patients. | The most important subgroup of breast cancer patients for whom reliable prognostic indicators are needed is women without axillary lymph node metastases. We evaluated the clinical significance of occult micrometastases in axillary lymph nodes in 148 consecutive "node-negative" breast cancer patients. The median age of ... | ['Adult', 'Aged', 'Breast Neoplasms', 'Disease-Free Survival', 'Female', 'Humans', 'Immunohistochemistry', 'Lymphatic Metastasis', 'Middle Aged', 'Neoplasm Metastasis', 'Prognosis', 'Proportional Hazards Models', 'Recurrence', 'Time Factors'] | 12,079,518 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Pathogen variation and urea influence selection and success of Streptomyces mixtures in biological control. | Success in biological control of plant diseases remains inconsistent in the field. A collection of well-characterized Streptomyces antagonists (n = 19 isolates) was tested for their capacities to inhibit pathogenic Streptomyces scabies (n = 15 isolates). There was significant variation among antagonists in ability to i... | ['Anti-Bacterial Agents', 'Antibiosis', 'Biological Control Agents', 'Drug Resistance, Multiple, Bacterial', 'Host-Pathogen Interactions', 'Phenotype', 'Plant Diseases', 'Plant Tubers', 'Soil Microbiology', 'Solanum tuberosum', 'Streptomyces', 'Urea'] | 23,035,630 | [['D27.505.954.122.085'], ['G06.550.050', 'G16.062'], ['D20.215.113'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['G06.462', 'G16.527.200'], ['G05.695'], ['G15.610'], ['A18.400.625'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['B01.650.940.800.575.912.250.90... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Final report of the FOPE II Financing of Pediatric Education Workgroup. | Some of the challenges of financing pediatric medical education are shared with all medical education; others are specific to pediatrics. The general disadvantage that funding of graduate medical education (GME) is linked to reimbursement for clinical care has uniquely negative consequences for freestanding children's ... | ['Child', 'Education, Medical', 'Education, Medical, Continuing', 'Health Maintenance Organizations', 'Humans', 'Managed Care Programs', 'Medicare', 'Pediatrics', 'Specialization', 'United States'] | 11,073,555 | [['M01.060.406'], ['I02.358.399'], ['I02.358.212.350', 'I02.358.399.250'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.590.374.410.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['N03.219.521.346.506.564.663', 'N03.2... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Problems in assessment of acute melatonin overdose. | Melatonin is sold in the United States as a dietary supplement and is promoted primarily as an aid for insomnia, stress, jet lag, and aging. Cases of acute poisoning have not been reported, partially because of problems in assessment of toxicity. We report the case of a 66-year-old man who became lethargic and disorien... | ['Acute Disease', 'Aged', 'Diagnosis, Differential', 'Drug Overdose', 'Humans', 'Male', 'Melatonin'] | 9,114,843 | [['C23.550.291.125'], ['M01.060.116.100'], ['E01.171'], ['C25.775.383', 'E02.319.306.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.914.481', 'D06.472.506']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of chronic kidney disease on patients with unprotected left main coronary artery disease treated with coronary artery bypass grafting or drug-eluting stents. | OBJECTIVES: This study aimed to evaluate clinical outcomes after percutaneous coronary intervention with drug-eluting stents (DESs) or coronary artery bypass grafting (CABG) in unprotected left main coronary artery (ULMCA) disease patients with and without chronic kidney disease.BACKGROUND: The optimal coronary revascu... | ['Aged', 'Biomarkers', 'Cause of Death', 'Chi-Square Distribution', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Creatinine', 'Drug-Eluting Stents', 'Female', 'Glomerular Filtration Rate', 'Humans', 'Kaplan-Meier Estimate', 'Kidney', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Myocardial Infarction', 'Per... | 27,269,882 | [['M01.060.116.100'], ['D23.101'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Methionine oxidation in albumin by fine haze particulate matter: an in vitro and in vivo study. | The potential effects of inhaled fine particulate matter (PM2.5), found in haze episodes, on the oxidation of the proteins in the lungs are not well understood. We investigated the effects of PM2.5 from haze episodes on protein oxidation. PM2.5 was collected from the air pollution in Beijing (BJ), Xian (XA), Xiamen (XM... | ['Air Pollutants', 'Albumins', 'Animals', 'Bronchoalveolar Lavage Fluid', 'Cell Line, Tumor', 'Female', 'Humans', 'Methionine', 'Mice, Inbred BALB C', 'Oxidation-Reduction', 'Oxidative Stress', 'Particulate Matter', 'Peptides', 'Polycyclic Aromatic Hydrocarbons', 'Reactive Oxygen Species'] | 24,801,896 | [['D27.888.284.101'], ['D12.776.034'], ['B01.050'], ['E05.927.100.500'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adverse psychologic responses of the elderly to critical illness. | Afflicting as many as 80% of critically ill elderly (older than 65 years) patients, adverse psychologic reactions (e.g., acute confusional states) to critical illness and its treatment present a unique challenge to medical and nursing intensive care practitioners. Additionally, the consequences of these adverse psychol... | ['Aged', 'Critical Illness', 'Geriatric Nursing', 'Health Facility Environment', 'Humans', 'Intensive Care Units', 'Stress, Psychological'] | 1,554,572 | [['M01.060.116.100'], ['C23.550.291.625'], ['H02.478.676.236', 'N02.421.533.245'], ['N02.278.220', 'N05.300.430.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['F01.145.126.990', 'F02.830.900']] | ['Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Occurrence of Ochratoxin A in the wild boar (Sus scrofa): chemical and histological analysis. | Ochratoxins are fungal secondary metabolites that may contaminate a broad variety of foodstuffs, such as grains, vegetables, coffee, dried fruits, beer, wine and meats. Ochratoxins are nephrotoxins, carcinogens, teratogens and immunotoxins in rats and are also likely to be in humans. In 2009/2010, a survey of the prese... | ['Animals', 'Carcinogens', 'Environmental Monitoring', 'Food Contamination', 'Kidney', 'Liver', 'Meat', 'Muscles', 'Ochratoxins', 'Sus scrofa', 'Urinary Bladder'] | 23,211,797 | [['B01.050'], ['D27.888.569.100'], ['N06.850.460.350.080', 'N06.850.780.375'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['A05.810.453'], ['A03.620'], ['G07.203.300.600', 'J02.500.600'], ['A02.633', 'A10.690'], ['D03.383.663.283.446.800.500', 'D03.633.100.150.446.800.500', 'D23.946.587.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Canine hepatocyte growth factor: molecular cloning and characterization of the recombinant protein. | Hepatocyte growth factor (HGF) is a pleiotropic cytokine originally identified and cloned as a potent mitogen for hepatocytes. The HGF receptor is the transmembrane tyrosine kinase encoded by c-MET proto-oncogene. Various lines of evidence suggest that the HGF/c-MET receptor system plays essential roles in monocyte-mac... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'COS Cells', 'Chlorocebus aethiops', 'Cloning, Molecular', 'Culture Media, Conditioned', 'DNA, Complementary', 'Dogs', 'Hepatocyte Growth Factor', 'Humans', 'Mice', 'Molecular Sequence Data', 'RNA', 'Recombinant Proteins', 'Reverse Transcriptase Polymerase Chain React... | 12,963,274 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.172.500', 'A11.329.228.220'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E05.393.220'], ['D27.720.470.305.250', 'E07.206.250'], ['D13.444.308.497.220', 'D13.444.600.223.500'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Use of the regressive models in linkage analysis of quantitative traits. | Use of the regressive models to account for residual familial correlations in linkage analysis of complex quantitative traits can increase the power to detect linkage. This is especially observed when the effect of the gene to be mapped is small or when the residual correlations are substantial. | ['Chromosome Mapping', 'Computer Simulation', 'Genetic Diseases, Inborn', 'Genetic Linkage', 'Humans', 'Lod Score', 'Models, Genetic', 'Monte Carlo Method'] | 8,314,065 | [['E05.393.183'], ['L01.224.160'], ['C16.320'], ['G05.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.348.750'], ['E05.599.395.397'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Copy number increases of transposable elements and protein-coding genes in an invasive fish of hybrid origin. | Evolutionary dynamics of structural genetic variation in lineages of hybrid origin is not well explored, although structural mutations may increase in controlled hybrid crosses. We therefore tested whether structural variants accumulate in a fish of recent hybrid origin, invasive Cottus, relative to both parental speci... | ['Animals', 'Biological Evolution', 'DNA Copy Number Variations', 'DNA Transposable Elements', 'Hybridization, Genetic', 'Introduced Species', 'Perciformes'] | 28,390,096 | [['B01.050'], ['G05.045', 'G16.075'], ['G05.365.795.297.500'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['E05.820.150.390', 'G05.090.390'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['B01.050.150.900.493.602']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[The comparative study of renogram both in case of dehydration and hydration (author's transl)]. | In order to study the merit or demerit of the dehydration or hydration as the preparation of renographic examination, the following 25 cases--11 cases of uterine cancer, 2 cases of breast cancer, a case of esophageal cancer, pharyngeal cancer, maxillary cancer, salivary gland tumor, leiomyosarcoma of uterus and others ... | ['Aged', 'Drinking', 'Female', 'Humans', 'Male', 'Middle Aged', 'Radioisotope Renography', 'Water Deprivation'] | 7,384,571 | [['M01.060.116.100'], ['G07.203.650.283.249', 'G10.261.330.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.710.715.700', 'E01.370.384.730.715.700', 'E01.370.390.400.700'], ['F01.658.938']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A study of voice production characteristics of astronuat speech during Apollo 11 for speaker modeling in space. | Human physiology has evolved to accommodate environmental conditions, including temperature, pressure, and air chemistry unique to Earth. However, the environment in space varies significantly compared to that on Earth and, therefore, variability is expected in astronauts' speech production mechanism. In this study, th... | ['Acoustics', 'Astronauts', 'Humans', 'Male', 'Space Flight', 'Speech Acoustics', 'Speech Production Measurement', 'Time Factors', 'Voice Quality', 'Weightlessness'] | 28,372,057 | [['H01.671.031'], ['M01.526.173'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.937.285.850'], ['G11.561.812.650', 'G11.561.820'], ['E01.370.760'], ['G01.910.857'], ['G09.772.925.960'], ['G01.060.350.369.400.900']] | ['Disciplines and Occupations [H]', 'Named Groups [M]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 |
Association of STAT6 and ADAM33 single nucleotide polymorphisms with asthma bronchiale and IgE level and its possible epigenetic background. | BACKGROUND: ADAM33 and STAT6 belong to the candidate genes that have been commonly associated with asthma, bronchial hyperresponsiveness or IgE levels. Our objective was to assess the association of 11 SNPs of the ADAM33 and 6 of the STAT6 and their haplotypes with IgE levels and asthma. We also evaluated the possible ... | ['ADAM Proteins', 'Adolescent', 'Asthma', 'Child', 'Child, Preschool', 'Epigenomics', 'Female', 'Haplotypes', 'Humans', 'Immunoglobulin E', 'Male', 'Polymorphism, Single Nucleotide', 'STAT6 Transcription Factor', 'Young Adult'] | 22,660,217 | [['D08.811.277.656.675.374.102', 'D09.400.430.500', 'D12.776.395.033'], ['M01.060.057'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['H01.158.273.180.350.074', 'H01.158.273.343.350.042'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Quality of life of occupationally active people, aged 45-60, living in the Polish industrial region (Silesian agglomeration)]. | BACKGROUND: Among the most important determinants of quality of life are socio-economic factors, including economic activity and support of family, environmental and indoor related factors, infrastructure and air quality. The aim of this publication is to identify the factors that determine the quality of life of econo... | ['Attitude to Health', 'Cross-Sectional Studies', 'Female', 'Health Behavior', 'Health Status', 'Humans', 'Life Style', 'Male', 'Middle Aged', 'Occupational Health', 'Occupations', 'Poland', 'Quality of Life', 'Socioeconomic Factors', 'Surveys and Questionnaires'] | 22,312,959 | [['F01.100.150', 'N05.300.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.488'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['M01.060.116.630'], ['N01.400.525'], ['N01.824.547'], ['Z01.542.248.6... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Phylogenetic relationships of yellowjackets inferred from nine loci (Hymenoptera: Vespidae, Vespinae, Vespula and Dolichovespula). | Eusociality has arisen repeatedly and independently in the history of insects, often leading to evolutionary success and ecological dominance. Eusocial wasps of the genera Vespula and Dolichovespula, or yellowjackets, have developed advanced social traits in a relatively small number of species. The origin of traits su... | ['Animals', 'Bayes Theorem', 'DNA, Mitochondrial', 'Genetic Loci', 'Genetic Markers', 'Phylogeny', 'Reproducibility of Results', 'Sequence Analysis, DNA', 'Wasps'] | 24,462,637 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['D13.444.308.283.225'], ['G05.360.340.024.380'], ['D23.101.387', 'G05.695.450'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.393.760.700'],... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Adherence of bacterial to vaginal epithelial cells. | Vaginal epithelial cells from healthy women were washed and incubated in tissue culture medium with freshly isolated bacteria of the indigenous vaginal flora and with bacteria of species that have been discussed in conjunction with genital infections. After incubation and washing, the number of bacteria that adhered pe... | ['Adolescent', 'Adult', 'Cell Adhesion', 'Corynebacterium', 'Culture Media', 'Epithelial Cells', 'Epithelium', 'Escherichia coli', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Lactobacillus acidophilus', 'Neisseria gonorrhoeae', 'Streptococcus agalactiae', 'Time Factors', 'Vagina'] | 5,372 | [['M01.060.057'], ['M01.060.116'], ['G04.022'], ['B03.510.024.250', 'B03.510.460.400.400.200'], ['D27.720.470.305', 'E07.206'], ['A11.436'], ['A10.272'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.481'], ['B03.353.750.450.475.100', 'B03.51... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Resolving chromosome-centric human proteome with translating mRNA analysis: a strategic demonstration. | Chromosome-centric human proteome project (C-HPP) aims at differentiating chromosome-based and tissue-specific protein compositions in terms of protein expression, quantification, and modification. We previously found that the analysis of translating mRNA (mRNA attached to ribosome-nascent chain complex, RNC-mRNA) can ... | ['Caco-2 Cells', 'Chromosomes, Human', 'Humans', 'Mass Spectrometry', 'Proteome', 'RNA, Messenger'] | 24,200,226 | [['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['A11.284.187.520.300', 'G05.360.162.520.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['D12.776.817'], ['D13.444.735.544']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A short-term clinical evaluation of IPS Empress 2 crowns. | PURPOSE: The aim of this study was to evaluate the clinical performance of all-ceramic crowns made with the IPS Empress 2 system after an observation period of 12 to 60 months.MATERIALS AND METHODS: Seventy-nine IPS Empress 2 crowns were placed in 21 patients. The all-ceramic crowns were evaluated clinically, radiograp... | ['Adolescent', 'Adult', 'Color', 'Composite Resins', 'Crowns', 'Dental Bonding', 'Dental Materials', 'Dental Porcelain', 'Dental Prosthesis Design', 'Dental Restoration Failure', 'Female', 'Follow-Up Studies', 'Glass', 'Humans', 'Lithium Compounds', 'Male', 'Middle Aged', 'Post and Core Technique', 'Surface Properties'... | 17,455,438 | [['M01.060.057'], ['M01.060.116'], ['G01.590.540.199'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.780.346.250', 'E07.695.190.088'], ['E06.095'], ['D25.339', 'D27.720.102.339', 'J01.637.051.339'], ['D25.339.376', 'J01.637.051.339.37... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease. | Although L-dopa remains the most effective treatment of Parkinson disease, its long-term administration is hampered by the appearance of dyskinesia. Hypersensitivity of dopamine D1 receptors in the striatum has been suggested to contribute to the genesis of these delayed adverse effects. However, D1 receptor amounts ar... | ['Aged', 'Aged, 80 and over', 'Animals', 'Antiparkinson Agents', 'Corpus Striatum', 'Female', 'GTP-Binding Protein alpha Subunits', 'Humans', 'Levodopa', 'Male', 'Middle Aged', 'Oxidopamine', 'Parkinson Disease', 'Putamen', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Dopamine D1', 'Sympatholytics'] | 15,295,036 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['D27.505.954.427.090.050'], ['A08.186.211.200.885.287.249.487'], ['D08.811.277.040.330.300.200.100', 'D12.644.360.360.100', 'D12.776.157.325.332.100', 'D12.776.476.375.100', 'D12.776.543.325.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.31... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Long-term neurocognitive dysfunction in offspring via NGF/ ERK/CREB signaling pathway caused by ketamine exposure during the second trimester of pregnancy in rats. | Early life exposure to ketamine caused neurohistopathologic changes and persistent cognitive dysfunction. For this study, a pregnant rat model was developed to investigate neurocognitive effects in the offspring, following ketamine exposure during the second trimester. Pregnant rats on gestational day 14 (equal to midt... | ['Animals', 'Biomarkers', 'Blood Gas Analysis', 'Blood Glucose', 'Cognitive Dysfunction', 'Cyclic AMP Response Element-Binding Protein', 'Extracellular Signal-Regulated MAP Kinases', 'Female', 'Hippocampus', 'Ketamine', 'Learning', 'Memory', 'Nerve Growth Factor', 'Pregnancy', 'Pregnancy Trimester, Second', 'Pyramidal ... | 28,415,680 | [['B01.050'], ['D23.101'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['D09.947.875.359.448.500'], ['F03.615.250.700'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['A08.186.211.180.405', 'A08.186.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Articular chondrocalcinosis and sliding knee prosthesis]. | The authors examined 24 files, involving 24 cases of arthroplastic knee surgery and revealing an articular chondrocalcinosis which was histologically proven. The mean post-operative follow-up took place in 30 months (1 to 5 years). The results were neither spectacular nor catastrophic. The overwhelming majority of the ... | ['Calcinosis', 'Follow-Up Studies', 'Humans', 'Joint Diseases', 'Knee Joint', 'Knee Prosthesis'] | 7,071,496 | [['C18.452.174.130'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550'], ['A02.835.583.475'], ['E07.695.400.410']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Integrated outpatient treatment of opioid use disorder and injection-related infections: A description of a new care model. | Persons with opioid use disorder (OUD) hospitalized with severe, injection-related infections (SIRI) are frequently hospitalized for the duration of IV antibiotic treatment due to concerns regarding their eligibility for outpatient parenteral antimicrobial therapy (OPAT), which is the standard of care for prolonged IV ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Ambulatory Care', 'Anti-Infective Agents', 'Buprenorphine', 'Delivery of Health Care, Integrated', 'Female', 'Humans', 'Infections', 'Male', 'Middle Aged', 'Narcotic Antagonists', 'Opiate Substitution Treatment', 'Opioid-Related Disorders', 'Pilot Projects', 'Practice Guidelines ... | 31,251,946 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.760.106', 'N02.421.585.106'], ['D27.505.954.122'], ['D03.132.577.249.150', 'D03.605.497.150', 'D03.633.400.686.150', 'D04.615.723.795.150'], ['N04.590.374.142', 'N05.300.262'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['M01.060.116.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Volumetric modulation arc radiotherapy with flattening filter-free beams compared with static gantry IMRT and 3D conformal radiotherapy for advanced esophageal cancer: a feasibility study. | PURPOSE: A feasibility study was performed to evaluate RapidArc (RA), and the potential benefit of flattening filter-free beams, on advanced esophageal cancer against intensity-modulated radiotherapy (IMRT) and three-dimensional conformal radiotherapy (3D-CRT).METHODS AND MATERIALS: The plans for 3D-CRT and IMRT with t... | ['Esophageal Neoplasms', 'Feasibility Studies', 'Heart', 'Humans', 'Lung', 'Matched-Pair Analysis', 'Organs at Risk', 'Radiation Injuries', 'Radiation Tolerance', 'Radiography', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Conformal', 'Radiotherapy, Intensity-Modulated', 'Spinal Cor... | 22,386,376 | [['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['E05.318.370.485', 'E05.318.740.475', 'N05.715.360.325.500',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Detection of occult disease in tissue donors by routine autopsy. | The transmission of infectious and neoplastic diseases is a potential risk of tissue allografting. In this study, we analyzed the occurrence of occult disease in tissue donors as detected by standard screening and autopsy. Whereas 18% of the potential donors initially evaluated were eliminated on the basis of their med... | ['Adolescent', 'Adult', 'Aged', 'Autopsy', 'Carrier State', 'Communicable Diseases', 'Humans', 'Middle Aged', 'Organ Transplantation', 'Tissue Donors'] | 9,561,683 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['N06.850.520.169'], ['C01.221', 'C23.550.291.531'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.936.450'], ['M01.898']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Transport of carbon colloid supported nanoscale zero-valent iron in saturated porous media. | Injection of nanoscale zero-valent iron (nZVI) has recently gained great interest as emerging technology for in-situ remediation of chlorinated organic compounds from groundwater systems. Zero-valent iron (ZVI) is able to reduce organic compounds and to render it to less harmful substances. The use of nanoscale particl... | ['Carbon', 'Environmental Pollutants', 'Environmental Restoration and Remediation', 'Iron', 'Metal Nanoparticles', 'Models, Chemical', 'Particle Size', 'Porosity', 'Povidone'] | 24,914,524 | [['D01.268.150'], ['D27.888.284'], ['N06.230.080.600', 'N06.850.460.375'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['J01.637.512.600.500'], ['E05.599.495'], ['G02.712'], ['G01.374.710'], ['D02.455.326.271.884.533.699', 'D03.383.773.812.615', 'D05.750.716.721.838', 'D25.720.716.721.838', 'J01.637.051.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Double semitendinous reconstruction of posterior cruciate ligament with invasive mini-plate technique]. | OBJECTIVE: To probe the clinical results of a new designed operation-double semitendinous reconstruction of posterior cruciate ligament (PCL) with invasive mini-plate.METHODS: The new surgical technique was performed on 28 patients with PCL deficient knee in our department from September 1994 to October 1997. Protectio... | ['Adolescent', 'Adult', 'Bone Plates', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Orthopedic Procedures', 'Posterior Cruciate Ligament', 'Reconstructive Surgical Procedures'] | 11,778,192 | [['M01.060.057'], ['M01.060.116'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718', 'E04.555'], ['A02.513.514.600', 'A02.835.583.512.600', 'A1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cultural consequences of miscarriages of justice. | Social science scholarship has tended to focus more on the causes than the consequences of miscarriages of justice. Within the literature on consequences, the overwhelming emphasis has been on individual consequences: psychological and material impacts on the wrongly convicted individual and, in some cases, other indir... | ['Bombs', 'Child', 'Child Abuse, Sexual', 'Child, Preschool', 'Culture', 'Female', 'Humans', 'Male', 'Public Opinion', 'Rape', 'Social Justice', 'Spain', 'United States'] | 19,402,029 | [['J01.637.870.175'], ['M01.060.406'], ['I01.198.240.748.300', 'I01.198.240.856.350.250.255', 'I01.880.735.900.350.250.255'], ['M01.060.406.448'], ['I01.076.201.450', 'I01.880.853.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.630.548'], ['I01.198.240.748.640', 'I01.198.240.856.744', 'I01.880.735.900... | ['Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Protective effects and active ingredients of Salvia miltiorrhiza Bunge extracts on airway responsiveness, inflammation and remodeling in mice with ovalbumin-induced allergic asthma. | BACKGROUND: Salvia miltiorrhiza Bunge (S. miltiorrhiza), a traditional Chinese medicine, has demonstrated antioxidant, anti-inflammatory, and antibacterial activities. However, its effects against asthma that shows chronic inflammation and oxidative damage remain unknown.PURPOSE: To assess the effects of S. miltiorrhiz... | ['Actins', 'Airway Remodeling', 'Animals', 'Asthma', 'Bronchoalveolar Lavage Fluid', 'Cell Line', 'Collagen', 'Collagen Type I', 'Cytokines', 'Epithelial-Mesenchymal Transition', 'Female', 'Fibrosis', 'Goblet Cells', 'Humans', 'Immunoglobulin E', 'Inflammation', 'Lung', 'Mice', 'Mice, Inbred BALB C', 'Ovalbumin', 'Plan... | 30,599,896 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['C23.300.017', 'G09.772.029'], ['B01.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.927.100.500'], ['A11.251.210'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D05.750.078.280.300.100', 'D12.776.860.300.25... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anion control of sodium absorption in the colon. | The regulatory functions of anions in colonic absorption of sodium are unknown. Absorption of sodium ions was assessed with chloride, butyrate, nitrite, sulphate and oxalate anions in segments of proximal/distal colon and in defunctioned colon. Efficiency of sodium absorption was related to availability of CO2 in mucos... | ['Absorption', 'Animals', 'Anions', 'Colon', 'In Vitro Techniques', 'Rats', 'Rats, Inbred Strains', 'Sodium'] | 3,714,959 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['D01.248.497.158'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['E05.481'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D01.268.549.750', 'D01.268.557.6... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Is it possible to predict amyloidogenic regions from sequence alone? | Identification of potentially amyloidogenic regions in polypeptide chains is very important because the amyloid fibril formation can be induced in most normal proteins. In our work we suggest a new method to detect amyloidogenic regions in protein sequence. It is based on the assumption that packing is tight inside an ... | ['Algorithms', 'Amino Acid Sequence', 'Amyloid', 'Molecular Sequence Data', 'Peptides', 'Protein Structure, Tertiary', 'Sequence Alignment', 'Sequence Analysis, Protein', 'Sequence Homology, Amino Acid'] | 16,819,789 | [['G17.035', 'L01.224.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D05.500.049', 'D12.776.049'], ['L01.453.245.667'], ['D12.644'], ['G02.111.570.820.709.610'], ['E05.393.751'], ['E05.393.760.705'], ['G02.111.810.200', 'G05.810.200']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Transfusion-associated graft-versus-host disease in immunocompetent patients: a self-protective mechanism. | Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare but hazardous complication caused by transfusion of leucocyte-containing blood. It is not clear why some patients are at risk for TA-GVHD, but others are not. We studied TA-GVHD in immunocompetent individuals by looking at donor-anti-host reactivity a... | ['Cells, Cultured', 'Clone Cells', 'Erythrocyte Transfusion', 'Graft vs Host Disease', 'HLA-DR Antigens', 'Histocompatibility Testing', 'Humans', 'Immunocompromised Host', 'Kidney Transplantation', 'Leukocyte Transfusion', 'Lymphocyte Activation', 'Lymphocyte Culture Test, Mixed', 'Lymphocytes'] | 7,907,730 | [['A11.251'], ['A11.251.353'], ['E02.095.135.140.275'], ['C20.452'], ['D12.776.395.550.509.400.440', 'D12.776.543.550.440.400.440', 'D23.050.301.500.400.400.440', 'D23.050.301.500.450.400.440', 'D23.050.705.552.410.400.440', 'D23.050.705.552.450.400.440'], ['E01.370.225.812.385', 'E05.200.812.385', 'E05.478.594.385'], ... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Panton-Valentine leukocidin facilitates the escape of Staphylococcus aureus from human keratinocyte endosomes and induces apoptosis. | Skin and soft-tissue infections (SSTIs) caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) have emerged as major health problems throughout the world. Most SSTI CA-MRSA strains produce Panton-Valentine leukocidin (PVL), but its contribution to CA-MRSA pathogenesis is poorly defined. He... | ['Animals', 'Apoptosis', 'Bacteria', 'Bacterial Toxins', 'Cell Line', 'Community-Acquired Infections', 'Disease Models, Animal', 'Endosomes', 'Exotoxins', 'Female', 'Gene Deletion', 'Genetic Complementation Test', 'Humans', 'Keratinocytes', 'Lagomorpha', 'Leukocidins', 'Methicillin-Resistant Staphylococcus aureus', 'Ra... | 23,956,440 | [['B01.050'], ['G04.146.954.035'], ['B03'], ['D23.946.123'], ['A11.251.210'], ['C01.234'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.284.430.214.190.875.190.880.337'], ['D23.946.350'], ['G05.365.590.762.320', 'G05.558.800.320'], ['E05.393.281.526'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
[Concentrations of fluorine, aluminum and magnesium in some structures of the central nervous system of rats exposed to aluminum and fluorine in drinking water]. | Fluorine and aluminum are able to pass through the blood-brain barrier and accumulate in the central nervous system (CNS) of exposed animals. Chronic intoxication is accompanied by behavioral disorders, degenerative changes, and abnormalities of aerobic metabolism of the neurons. Awareness of the role of aluminum in Al... | ['Aluminum', 'Animals', 'Blood-Brain Barrier', 'Brain Chemistry', 'Cerebellum', 'Cerebral Cortex', 'Environmental Exposure', 'Environmental Monitoring', 'Female', 'Fluorine', 'Hippocampus', 'Magnesium', 'Male', 'Rats', 'Rats, Wistar', 'Water Pollutants, Chemical', 'Water Supply'] | 16,892,590 | [['D01.268.557.050', 'D01.552.547.050'], ['B01.050'], ['A07.035', 'A08.186.211.035'], ['G02.111.150', 'G03.185'], ['A08.186.211.132.810.428.200'], ['A08.186.211.200.885.287.500'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D01.268.380.300'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Spectrofluorometric studies of the lipid probe, nile red. | We found that the dye nile red, 9-diethylamino-5H-benzo[alpha]phenoxazine-5-one, can be applied as a fluorescent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytofluorometry (J. Cell. Biol. 1985. 100: 965-973). To understand the selectivity of the staining, we examin... | ['Adipose Tissue', 'Animals', 'Chemical Phenomena', 'Chemistry, Physical', 'Lipids', 'Microsomes, Liver', 'Oxazines', 'Proteins', 'Rats', 'Solvents', 'Spectrometry, Fluorescence'] | 4,031,658 | [['A10.165.114'], ['B01.050'], ['G02'], ['H01.181.529'], ['D10'], ['A11.284.835.540.541'], ['D03.383.533'], ['D12.776'], ['B01.050.150.900.649.313.992.635.505.700'], ['D27.720.844'], ['E05.196.712.516.600.676', 'E05.196.867.726']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultraviolet damage to bacteria and bacteriophage at low temperatures. | The survival of Escherichia coli B/r WP2 (tryptophan-requiring) from ultraviolet irradiation when suspended in 0.067M phosphate buffer (pH 7) has been studied over the temperature range 22 degrees to -269 degrees C. In unfrozen suspensions there was no appreciable change in sensitivity between 22 degrees and -10 degree... | ['Cold Temperature', 'Coliphages', 'Culture Media', 'Escherichia coli', 'Freezing', 'In Vitro Techniques', 'Radiation Genetics', 'Thymine', 'Tryptophan', 'Ultraviolet Rays'] | 5,318,093 | [['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['B04.123.205'], ['D27.720.470.305', 'E07.206'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['E05.481'], ['H01.158... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Fast bowling match workloads over 5-26 days and risk of injury in the following month. | OBJECTIVES: This study examined whether high match fast bowling workloads in the short to medium term were associated with increased bowling injury rates.DESIGN: Prospective cohort study.METHODS: Over a 15 year period, workload patterns for 235 individual fast bowlers during time periods from 5 to 26 days were examined... | ['Athletic Injuries', 'Australia', 'Humans', 'Prospective Studies', 'Risk Assessment', 'Risk Factors', 'Sports', 'Time Factors', 'Workload'] | 25,245,426 | [['C26.115'], ['Z01.639.100', 'Z01.678.100.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], [... | ['Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
In vitro activity of biapenem against clinical isolates of gram-positive and gram-negative bacteria. | The in vitro activity of biapenem, a new carbapenem previously designated L-627, was compared with those of imipenem and several other antimicrobial agents against 771 clinical bacterial isolates. Against gram-positive organisms, biapenem was found to be approximately as active as imipenem, inhibiting 90% of isolates o... | ['Anti-Bacterial Agents', 'Gram-Negative Bacteria', 'Gram-Negative Bacterial Infections', 'Gram-Positive Bacteria', 'Gram-Positive Bacterial Infections', 'Humans', 'Imipenem', 'Methicillin Resistance', 'Microbial Sensitivity Tests', 'Thienamycins'] | 8,239,623 | [['D27.505.954.122.085'], ['B03.440'], ['C01.150.252.400'], ['B03.510'], ['C01.150.252.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.099.124.300.500', 'D03.633.100.300.124.300.500'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525', 'G07.690.773.984.269.347.500.600.525'], ['E01.370.225.875.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The safety, efficacy, and pharmacoeconomics of low-dose alteplase compared with urokinase for catheter-directed thrombolysis of arterial and venous occlusions. | PURPOSE: The purpose of this study was to compare the efficacy, complications, and costs associated with low-dose (<2 mg/h) alteplase (tissue plasminogen activator [t-PA]) versus urokinase for the catheter-directed treatment of acute peripheral arterial occlusive disease (PAO) and deep vein thrombosis (DVT).MATERIALS A... | ['Adult', 'Aged', 'Arterial Occlusive Diseases', 'Extremities', 'Female', 'Fibrinolytic Agents', 'Heparin', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Plasminogen Activators', 'Retrospective Studies', 'Thrombolytic Therapy', 'Tissue Plasminogen Activator', 'Treatment Outcome', 'Urokinase-Type Plasminogen Acti... | 12,618,684 | [['M01.060.116'], ['M01.060.116.100'], ['C14.907.137'], ['A01.378'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Recognition memory for text and melody of songs after unilateral temporal lobe lesion: evidence for dual encoding. | The role of left and right temporal lobes in memory for songs (words sung to a tune) was investigated. Patients who had undergone focal cerebral excision for the relief of intractable epilepsy along with normal control subjects were tested in 2 recognition memory tasks. The goal of Experiment 1 was to examine recogniti... | ['Attention', 'Brain Damage, Chronic', 'Brain Mapping', 'Dominance, Cerebral', 'Epilepsy, Temporal Lobe', 'Humans', 'Mental Recall', 'Music', 'Pitch Perception', 'Postoperative Complications', 'Psychosurgery', 'Retention, Psychology', 'Temporal Lobe', 'Verbal Learning'] | 1,832,437 | [['F02.830.104.214'], ['C10.228.140.140'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.830.297', 'G11.561.225'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['K01.602'], ['F02.463.593.071.700', 'G0... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Humanities [K]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tumour mutation status and sites of metastasis in patients with cutaneous melanoma. | BACKGROUND: Cutaneous melanoma can metastasise haematogenously and/or lymphogenously to form satellite/in-transit, lymph node or distant metastasis. This study aimed to determine if BRAF and NRAS mutant and wild-type tumours differ in their site of first tumour metastasis and anatomical metastatic pathway.METHODS: Pros... | ['Adult', 'Aged', 'Aged, 80 and over', 'Central Nervous System Neoplasms', 'Female', 'GTP Phosphohydrolases', 'Humans', 'Liver Neoplasms', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Melanoma', 'Membrane Proteins', 'Middle Aged', 'Neoplastic Cells, Circulating', 'Prospective Studies', 'Proto-Oncogene Proteins B-... | 28,787,433 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.614.250', 'C10.551.240'], ['D08.811.277.040.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.650.560', 'C23.550.727.650.560... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of isoquinoline alkaloids, diterpenoids and steroids in the Chinese herb Jin-Guo-Lan (Tinospora sagittata and Tinospora capillipes) by high-performance liquid chromatography/electrospray ionization with multistage mass spectrometry. | This study sought to determine the primary components (isoquinoline alkaloids, diterpenoids and steroids) in crude extracts of the Chinese herb Jin-Guo-Lan, prepared from the roots of Tinospora sagittata and T. capillipes, by liquid chromatography/electrospray ionization multistage mass spectrometry coupled with diode-... | ['Alkaloids', 'Chromatography, High Pressure Liquid', 'Diterpenes', 'Drugs, Chinese Herbal', 'Isoquinolines', 'Plant Extracts', 'Spectrometry, Mass, Electrospray Ionization', 'Steroids', 'Tinospora'] | 16,817,243 | [['D03.132'], ['E05.196.181.400.300'], ['D02.455.849.291'], ['D20.215.784.500.350', 'D26.335'], ['D03.633.100.531'], ['D20.215.784.500', 'D26.667'], ['E05.196.566.600'], ['D04.210.500'], ['B01.650.940.800.575.912.250.725.875']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of probucol on QT/QS2 relation and systolic time intervals. | The QT, QTc, QS2 intervals, pre-ejection period-left ventricular ejection time ratios and serum lipoprotein levels were measured in 8 patients with primary hypercholesterolemia before and after a 3-month therapy with probucol, 1 g/day. Both QT and QTc intervals increased significantly, whereas no significant changes we... | ['Adult', 'Arrhythmias, Cardiac', 'Cardiac Output', 'Cholesterol', 'Electrocardiography', 'Female', 'Humans', 'Hypercholesterolemia', 'Lipoproteins', 'Long QT Syndrome', 'Male', 'Middle Aged', 'Myocardial Contraction', 'Phenols', 'Probucol', 'Systole'] | 3,397,194 | [['M01.060.116'], ['C14.280.067', 'C23.550.073'], ['E01.370.370.380.150', 'G09.330.380.124'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.396'], ['D10.532', 'D12.776.521'], [... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A randomized double-blind study of atenolol and celiprolol in mild to moderate hypertension. | The antihypertensive effects of equivalent beta-blocking doses of atenolol and celiprolol were compared in 55 patients with mild to moderate hypertension. Patients with diastolic blood pressure between 95 and 114 mm Hg were randomized to celiprolol or atenolol once daily. The dose of each agent was titrated from 50 to ... | ['Adrenergic beta-Antagonists', 'Atenolol', 'Celiprolol', 'Clinical Trials as Topic', 'Double-Blind Method', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Propanolamines', 'Random Allocation'] | 2,427,841 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['D02.033.100.624.698.268', 'D02.033.755.624.698.268', 'D02.065.950.681.241', 'D02.092.063.624.698.268', 'D02.455.426.559.389.703.241'], ['E05.318.372.250.250', 'N05.715.36... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of mirabegron on patient-related outcomes in patients with overactive bladder: the results of post hoc correlation and responder analyses using pooled data from three randomized Phase III trials. | PURPOSE: To understand how improvements in the symptoms of overactive bladder (OAB) seen with the â3-adrenoceptor agonist mirabegron 50 mg, correlate with patient experience as measured by validated and standard patient-reported outcomes (PROs), and to identify whether there is overall directional consistency in the re... | ['Acetanilides', 'Aged', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Quality of Life', 'Surveys and Questionnaires', 'Thiazoles', 'Treatment Outcome', 'Urinary Bladder, Overactive', 'Urinary Incontinence', 'Urological Agents'] | 25,688,038 | [['D02.065.199.092', 'D02.092.146.113.092'], ['M01.060.116.100'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cyclooxygenase-2 in human non-small cell lung cancer. | AIM: Recent studies report that the expression of cyclooxygenase (COX) in non-small cell lung cancer (NSCLC) is increased, especially in adenocarcinoma. Platelet activating factor (PAF), n-sodium butyrate (n-BT), and phorbol myristate acetate (PMA) are important mediators of the inflammatory process.METHOD: Expression ... | ['Aged', 'Butyrates', 'Carcinoma, Non-Small-Cell Lung', 'Cyclooxygenase 2', 'Female', 'Humans', 'Immunoblotting', 'Immunohistochemistry', 'Inflammation Mediators', 'Isoenzymes', 'Lung Neoplasms', 'Male', 'Membrane Proteins', 'Platelet Activating Factor', 'Prostaglandin-Endoperoxide Synthases', 'Reverse Transcriptase Po... | 12,633,561 | [['M01.060.116.100'], ['D02.241.081.114', 'D10.251.400.143'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D08.811.600.720.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Ultrastructural and histochemical characteristics of embryonic hepatocytes exposed to ethanol]. | The induction of ethanol (10 and 40% concentration) to pregnant female rats causes embryolethal effect, inhibition of fetus development, breaks morphofunctional state of embryo liver, causes hydropathic vacuolization of hepatic cells, lowering of DNA and RNA level in them, breaks penetrability of vascular walls. Ethano... | ['Animals', 'Ethanol', 'Female', 'Gestational Age', 'Histocytochemistry', 'Liver', 'Liver Glycogen', 'Microscopy, Electron', 'Mitosis', 'Pregnancy', 'Rats', 'Rats, Inbred Strains'] | 7,147,342 | [['B01.050'], ['D02.033.375'], ['G07.345.500.325.235.968', 'G08.686.320'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['A03.620'], ['D05.750.078.562.388.518', 'D09.698.365.388.518'], ['E01.370.350.515.402', 'E05.595.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of cancer care and outcomes between a public safety-net hospital and a private cancer center. | We compared the cancer outcomes and care-associated service defects between Jackson Memorial Hospital (ABC), a large public safety-net hospital, and Sylvester Comprehensive Cancer Center (XYZ), a private not-for-profit cancer center in patients with stage II-III colorectal cancer (CC) who received adjuvant chemotherapy... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cancer Care Facilities', 'Colorectal Neoplasms', 'Disease-Free Survival', 'Female', 'Hospitals, General', 'Hospitals, Voluntary', 'Humans', 'Male', 'Middle Aged', 'Poverty', 'Safety-net Providers', 'Treatment Outcome', 'Young Adult'] | 23,974,387 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N02.278.421.556.070'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', ... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Dumping syndrome in children. | Dumping syndrome developed in seven children after gastric surgery, (Nissen fundoplication in six, Whipple procedure in one). The patients ranged from age 10 months to 13 years, and four of the seven were neurologically impaired. The diagnosis was made by demonstrating an abnormal response to an orally administered glu... | ['Child', 'Child, Preschool', 'Dumping Syndrome', 'Gastric Fundus', 'Humans', 'Infant', 'Postoperative Complications'] | 3,806,293 | [['M01.060.406'], ['M01.060.406.448'], ['C06.405.748.630.310', 'C23.550.767.812.500'], ['A03.556.875.875.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C23.550.767']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A tale of two stories: astrocyte regulation of synaptic depression and facilitation. | Short-term presynaptic plasticity designates variations of the amplitude of synaptic information transfer whereby the amount of neurotransmitter released upon presynaptic stimulation changes over seconds as a function of the neuronal firing activity. While a consensus has emerged that the resulting decrease (depression... | ['Astrocytes', 'Calcium', 'Computer Simulation', 'Hippocampus', 'Models, Neurological', 'Neuronal Plasticity', 'Neurotransmitter Agents', 'Synapses', 'Synaptic Transmission'] | 22,162,957 | [['A08.637.200', 'A11.650.200'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['L01.224.160'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E05.599.395.642'], ['G11.561.638'], ['D27.505.519.625', 'D27.505.696.577'], ['A08.850', 'A11.284.149.165.420.780'], ['G02.111.820.850', 'G04.835.850', 'G... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Group trajectory analysis helps to identify older cancer survivors who benefit from distance-based lifestyle interventions. | BACKGROUND: The number of older cancer survivors is increasing as more adults survive to older ages. The objectives of this study were to examine trajectories of physical activity (PA) and physical function (PF) over a 2-year lifestyle counseling study and to identify characteristics of the trajectory groups.METHODS: T... | ['Activities of Daily Living', 'Aged', 'Body Mass Index', 'Breast Neoplasms', 'Canada', 'Colorectal Neoplasms', 'Counseling', 'Female', 'Humans', 'Male', 'Motor Activity', 'Neoplasms', 'Overweight', 'Prostatic Neoplasms', 'Risk Reduction Behavior', 'Self Efficacy', 'Survivors', 'Telephone', 'United Kingdom', 'United St... | 26,512,712 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.180', 'C17.800.090.500'], ['Z01.107.567.176'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Effect of thermal expansion on the accuracy of fit of cast crowns]. | Extent and direction of dimensional changes in the finished cast crown resulting from the thermic expansion of the wax model are determined as a function of the time the crown was subjected to tempering as a function of tempering temperature. Expansion of the wax model does not come up to the expectation of preventing ... | ['Crowns', 'Dental Casting Investment', 'Dental Casting Technique', 'Dental Models', 'Humans', 'Inlay Casting Wax', 'Temperature'] | 1,091,456 | [['E06.780.346.250', 'E07.695.190.088'], ['D25.339.250', 'J01.637.051.339.250'], ['E06.780.250', 'E06.912.115'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D25.339.334.574', 'J01.637.051.339.334.574'], ['G01.906.595', 'G16.500.275.063.72... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
The effect of split virus influenza vaccination on theophylline pharmacokinetics. | The effects of split virus influenza vaccine on the pharmacokinetics of theophylline and the in vivo and in vitro induction of interferon were studied in 23 volunteers. No effect on the total body clearance, half-life, or mean residence time of theophylline was found as a result of influenza virus vaccine. Additionally... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Humans', 'Influenza Vaccines', 'Influenza, Human', 'Interferons', 'Kinetics', 'Lung Diseases, Obstructive', 'Male', 'Middle Aged', 'Theophylline', 'Vaccination'] | 2,408,526 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['G01.374.661', 'G02.111.490'], ['C08.381.495'], ['M01.060.116.630']... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Postoperative wound infection surveillance by use of bacterial contamination categories. | A prospective 2-year surveillance of 7129 wounds was conducted on all surgical services of the University Hospital in Seattle to determine the postoperative infection rates by surgical wound category. Rates on all services for clean (0.8%), clean-contaminated (3.4%), contaminated (3.6%), and dirty (9.9%) wounds were re... | ['Bacterial Infections', 'Female', 'Hospital Bed Capacity, 300 to 499', 'Humans', 'Male', 'Prospective Studies', 'Risk', 'Surgical Procedures, Operative', 'Surgical Wound Infection', 'Washington'] | 3,850,727 | [['C01.150.252'], ['N02.278.306.472.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800'], ['E04'], ['C01.947.692', 'C23.550.767.925']... | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The pharmacodynamics of ivermectin in sheep and cattle. | The concentrations of ivermectin in the gastrointestinal tract of sheep and cattle were determined after subcutaneous administration of ivermectin. Ivermectin was not detected (limit of detection 1 ng/ml) in abomasal and ruminal fluids either after a normal therapeutic dose of 200 micrograms/kg or even at an increased ... | ['Animals', 'Bile', 'Cattle', 'Duodenum', 'Gastrointestinal Contents', 'Ileum', 'Ivermectin', 'Milk', 'Sheep', 'Species Specificity'] | 3,184,266 | [['B01.050'], ['A12.200.087'], ['B01.050.150.900.649.313.500.380.271'], ['A03.556.124.684.124', 'A03.556.875.249'], ['A12.519'], ['A03.556.124.684.249', 'A03.556.249.124'], ['D02.540.576.500.997'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['B01.050.150.900.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Neuroprotective effects of colchicine in the gerbil model of cerebral ischaemia. | The tropolonic alkaloid colchicine significantly reduces the behavioural, electroencephalographic and histological damage seen after a 6-min occlusion of the two common carotid arteries of the Mongolian gerbil if the compound is administered at 2 or 4 mg/kg i.p. immediately upon reperfusion. A 45% increase in high-freq... | ['Animals', 'Avoidance Learning', 'Behavior, Animal', 'Body Temperature', 'Brain Ischemia', 'Carotid Artery, Common', 'Cell Death', 'Colchicine', 'Electroencephalography', 'Gerbillinae', 'Male', 'Motor Activity', 'Neurons'] | 8,047,263 | [['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F01.145.113'], ['E01.370.600.875.374', 'G07.110'], ['C10.228.140.300.150', 'C14.907.253.092'], ['A07.015.114.186.200'], ['G04.146'], ['D03.132.225'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.992.635.300'], ['F01.145.632', 'G11.427.410.... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term outcomes after surgical resection for gastric cancer liver metastasis: an analysis of 64 macroscopically complete resections. | PURPOSE: The indication for hepatectomy in cases of gastric cancer liver metastases (GLM) remains unclear and it remains controversial whether surgical resection is beneficial for GLM. The objective of this retrospective study was to clarify the indications for and benefit of hepatectomy for GLM.METHODS: Seventy-three ... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Cohort Studies', 'Disease-Free Survival', 'Female', 'Gastrectomy', 'Hepatectomy', 'Humans', 'Kaplan-Meier Estimate', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', 'N... | 22,615,045 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', ... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
ABO hemolytic disease of the fetus and newborn: thirteen years of data after implementing a universal bilirubin screening and management program. | OBJECTIVE: ABO hemolytic disease occurs among neonates with blood groups A or B delivered to group O women. Extreme neonatal hyperbilirubinemia due to ABO disease has been reported, but its frequency is not well known. We sought to determine the odds of developing severe ABO hemolytic disease in the 13 years since adop... | ['ABO Blood-Group System', 'Bilirubin', 'Databases, Factual', 'Erythroblastosis, Fetal', 'Female', 'Hemolysis', 'Humans', 'Hyperbilirubinemia, Neonatal', 'Infant, Newborn', 'Kernicterus', 'Male', 'Patient Readmission', 'Retrospective Studies', 'Utah'] | 29,410,540 | [['D23.050.301.290.031', 'D23.050.705.230.031'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['C13.703.277.060', 'C15.378.295', 'C16.300.060', 'C16.614.304', 'C20.306'], ['C23.550.403', 'G12.122.545'], ['B01.05... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Analyses of signal transduction cascades reveal an essential role of calcium ions for regulation of melatonin biosynthesis in the light-sensitive pineal organ of the rainbow trout (Oncorhynchus mykiss). | Signal transduction processes regulating melatonin production in the light-sensitive trout pineal organ were investigated by immunocytochemical and immunochemical demonstration of phosphorylated cyclic AMP-responsive element-binding protein (pCREB) and measurements of cyclic AMP, melatonin, and calcium levels. Melatoni... | ['1-Methyl-3-isobutylxanthine', 'Animals', 'Arylamine N-Acetyltransferase', 'Calcium', 'Calcium Signaling', 'Colforsin', 'Cyclic AMP', 'Cyclic AMP Response Element-Binding Protein', 'Cysteine Endopeptidases', 'Female', 'Gene Expression', 'Immunohistochemistry', 'Male', 'Melatonin', 'Multienzyme Complexes', 'Oncorhynchu... | 10,820,209 | [['D03.633.100.759.758.824.751.500'], ['B01.050'], ['D08.811.913.050.134.138'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Parenchymal versus reticuloendothelial iron overload in the liver: distinction with MR imaging. | Parenchymal iron deposition occurs in hemochromatosis, while iron is deposited in reticuloendothelial (RE) cells after blood transfusions or rhabdomyolysis. Magnetic resonance images of patients with decreased liver signal intensity on T2-weighted images at 1.5 T were blindly compared in an effort to distinguish these ... | ['Adolescent', 'Adult', 'Biopsy', 'Female', 'Hemochromatosis', 'Humans', 'Iron', 'Kupffer Cells', 'Liver', 'Liver Cirrhosis', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Pancreas', 'Retrospective Studies', 'Spleen', 'Transfusion Reaction'] | 2,014,275 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C16.320.565.618.337', 'C18.452.565.500.480', 'C18.452.648.618.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
ANCA-negative pauci-immune crescentic glomerulonephritis complicated with recurrent massive gastrointestinal hemorrhage. | On April 25, 2003, a 62-year-old Japanese man had been admitted to a hospital because of heavy proteinuria and elevated serum creatinine level, and purpura on the lower extremities. On May 15, 2003, he was referred to our hospital for evaluation and treatment. Serum immunoglobulin and complements were within normal ran... | ['Angiography', 'Antibodies, Antineutrophil Cytoplasmic', 'Gastrointestinal Hemorrhage', 'Glomerulonephritis', 'Humans', 'Kidney Glomerulus', 'Male', 'Mesenteric Arteries', 'Microscopy, Electron', 'Middle Aged', 'Recurrence'] | 15,980,955 | [['E01.370.350.700.060', 'E01.370.370.050'], ['D12.776.124.486.485.114.323.190', 'D12.776.124.790.651.114.323.190', 'D12.776.377.715.548.114.323.190', 'D23.101.050'], ['C06.405.227', 'C23.550.414.788'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.32... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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