Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The developmental course of inattention symptoms predicts academic achievement due to shared genetic aetiology: a longitudinal twin study. | Symptoms of attention-deficit hyperactivity disorder, in particular inattention symptoms, are associated with academic achievement. However, whether and why the developmental course of inattention symptoms (i.e. systematic decreases or increases of symptoms with age) predicts academic achievement remains unclear. A tot... | ['Academic Success', 'Adolescent', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Twins'] | 30,006,673 | [['I02.399.136.500'], ['M01.060.057'], ['F03.625.094.150'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['M01.438.873']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Energy coupling to periplasmic binding protein-dependent transport systems: stoichiometry of ATP hydrolysis during transport in vivo. | Periplasmic binding protein-dependent transport systems mediate the accumulation of many diverse substrates in prokaryotic cells. Similar transport systems, including the P-glycoprotein responsible for multidrug resistance in human tumors, are also found in eukaryotes. The mechanism by which energy is coupled to the ac... | ['ATP-Binding Cassette Transporters', 'Adenosine Triphosphate', 'Betaine', 'Biological Transport, Active', 'Carrier Proteins', 'Chemotactic Factors', 'Chemotaxis', 'Energy Metabolism', 'Escherichia coli', 'Escherichia coli Proteins', 'Genotype', 'Glycine', 'Hydrolysis', 'Maltose', 'Maltose-Binding Proteins', 'Monosacch... | 2,682,642 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D02.092.877.883.077', 'D02.675.276.125'], ['G03.143.310'], ['D12.776.157'], ['D23.125'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enactment in schizophrenia: capacity for dialogue and the experience of the inability to commit to action. | While research has steadily begun to explore thoughts and beliefs linked with helplessness and despair in schizophrenia, it is less clearly understood how to account phenomenologically for the related experience of being unable to commit to action in the midst of grave discomfort. To explore this issue, the current pap... | ['Adaptation, Psychological', 'Attitude to Health', 'Communication', 'Depression', 'Fear', 'Humans', 'Male', 'Middle Aged', 'Psychotherapy', 'Schizophrenia, Paranoid', 'Social Behavior'] | 16,704,334 | [['F01.058'], ['F01.100.150', 'N05.300.150'], ['F01.145.209', 'L01.143'], ['F01.145.126.350'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.754'], ['F03.700.750.600'], ['F01.145.813']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Experimental and empirical evidence shows that reducing weed control in winter cereal fields is a viable strategy for farmers. | Modern agriculture needs a paradigm shift to make the world's food production sustainable while mitigating social and environmental externalities. Although various policies to limit the use of agrochemicals have recently been implemented in the European Union, the use of both herbicides and fertilizers has remained fai... | ['Agriculture', 'Algorithms', 'Biomass', 'Cost-Benefit Analysis', 'Crops, Agricultural', 'Edible Grain', 'Farmers', 'Fertilizers', 'France', 'Geography', 'Herbicides', 'Nitrogen', 'Seasons', 'Weed Control'] | 31,227,731 | [['J01.040'], ['G17.035', 'L01.224.050'], ['G16.500.275.157.100', 'N06.230.124.100'], ['N03.219.151.125'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['M01.526.390']... | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 |
Extracellular alkaline phosphatase activity as a possible marker for wound healing: a preliminary report. | PURPOSE: This study evaluated the use of extracellular alkaline phosphatase activity as a marker of wound healing.MATERIALS AND METHODS: Fifteen 8-week-old Wistar rats, weighing 180 to 220 g and of both sexes, made up the material of this study. Histopathologic aspects of the healing of full-thickness of wounds created... | ['Alkaline Phosphatase', 'Animals', 'Biomarkers', 'Extracellular Space', 'Female', 'Male', 'Rats', 'Rats, Wistar', 'Wound Healing'] | 8,994,469 | [['D08.811.277.352.650.035'], ['B01.050'], ['D23.101'], ['A10.082.500', 'A11.284.295'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['G16.762.891']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Low-invasive colposuspension in stress enuresis in females]. | Retropubic colposuspension (RC) is one of leading surgical treatments of stress enuresis in women. A low-traumatic method of RC with application of special surgical instruments is proposed. Retropubic urethrocervicopexy and low-invasive colposuspension were made in 27 and 17 women, respectively. 25 women have undergone... | ['Adult', 'Female', 'Humans', 'Middle Aged', 'Surgical Instruments', 'Urinary Incontinence, Stress', 'Urologic Surgical Procedures'] | 15,199,817 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.858.700'], ['C12.777.934.852.249', 'C13.351.968.934.814.500', 'C23.888.942.343.800.500'], ['E04.950.774']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of synovitis and joint destruction by a new single domain antibody specific for cyclophilin A in two different mouse models of rheumatoid arthritis. | INTRODUCTION: Cyclophilin A (CypA) is implicated in rheumatoid arthritis (RA) pathogenesis. We studied whether a novel anti-CypA single domain antibody (sdAb) treatment would modulate the severity of the disease in two different animal models of RA.METHODS: A novel sdAb, named sdAbA1, was screened from an immunized cam... | ['Animals', 'Ankle Joint', 'Arthritis, Experimental', 'Arthritis, Rheumatoid', 'Blotting, Western', 'Cell Line', 'Cyclophilin A', 'Disease Models, Animal', 'Humans', 'Mice', 'Mice, Inbred DBA', 'Mice, Inbred NOD', 'Mice, SCID', 'Monocytes', 'Signal Transduction', 'Single-Domain Antibodies', 'Surface Plasmon Resonance',... | 24,314,202 | [['B01.050'], ['A02.835.583.378.062'], ['C05.550.114.015', 'E05.598.500.249'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['D08.811.399.325.500.400.300.500'], ['C22.232', 'E05... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of a new Spin-echo diffusion-weighted sequence on a 0.35 T open magnetic resonance imaging (MRI)-system: first experiences within 3 h after acute stroke. | In acute stroke, diffusion-weighted magnetic resonance imaging helps to select patients who are eligible for thrombolysis, but is almost exclusively implemented on closed-bore scanners, which make monitoring of patients difficult. We developed and tested a cardiac gated Spin-echo diffusion-weighted sequence with presca... | ['Adult', 'Aged', 'Cerebral Hemorrhage', 'Cerebral Infarction', 'Diffusion Magnetic Resonance Imaging', 'Echo-Planar Imaging', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Prospective Studies', 'Sensitivity and Specificity', 'Single-Blind Method', 'Stroke', 'Tomography, X-Ray Computed'] | 15,951,998 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['E01.370.350.825.500.150'], ['E01... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Comparative echocardiographic and vectorcardiographic study of 17 patients with Duchenne muscular dystrophy (author's transl)]. | Cardiac impairment in Duchenne muscular dystrophy (DMD) is well known since many years. Degeneration of myocardial fibers and progressive scarring of the left ventricle, especially in the postero-basal and lateral portions, represent the habitual cardiac pathologic features of post-mortem investigations. Nevertheless m... | ['Adolescent', 'Adult', 'Cardiomyopathies', 'Child', 'Child, Preschool', 'Echocardiography', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Muscular Dystrophies', 'Vectorcardiography'] | 261,956 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Herpes simplex virus thymidine kinase and specific stages of latency in murine trigeminal ganglia. | From marker rescue, sequencing, transcript, and latency analyses of the thymidine kinase-negative herpes simplex virus mutant dlsactk and studies using the thymidine kinase inhibitor Ro 31-5140, we infer that the virus-encoded thymidine kinase is required in murine trigeminal ganglia for acute replication and lytic gen... | ['Animals', 'Base Sequence', 'DNA Primers', 'Genes, Viral', 'Mice', 'Molecular Sequence Data', 'Simplexvirus', 'Thymidine Kinase', 'Trigeminal Ganglion', 'Viral Structural Proteins', 'Virus Latency', 'Virus Replication'] | 8,411,396 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['B04.280.382.100.750'], ['D08.811... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Transurethral deep desication]. | With a special plate electrode introduced through a regular resectoscope it is possible to desiccate tissue in a depth of 6 mm. This "deep desiccation" is used especially in transurethral resection of urothelial tumors of the bladder and in the radical resection of carcinoma of the prostate. The indications for partial... | ['Electrodes', 'Electrosurgery', 'Humans', 'Male', 'Prostatic Neoplasms', 'Urethral Neoplasms'] | 7,404,883 | [['E07.305.250'], ['E04.262'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['C04.588.945.947.945', 'C12.758.820.937', 'C12.777.767.601', 'C13.351.937.820.890', 'C13.351.968.767.601']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Automatic activation of motor programs by object affordances in patients with Parkinson's disease. | Clinical observations of kinesia paradoxica and freezing in patients with Parkinson's disease suggest that the automatic activation of motor programmes by visual stimuli may not require intact basal ganglia function, and that an increased sensitivity to such object affordances may contribute to some symptoms of the dis... | ['Aged', 'Female', 'Hand Strength', 'Humans', 'Male', 'Middle Aged', 'Motor Skills', 'Parkinson Disease', 'Photic Stimulation', 'Psychophysics', 'Reaction Time'] | 19,616,073 | [['M01.060.116.100'], ['E01.370.600.425.500', 'G11.427.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.808.260'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['E05.723.729'], ['E01.370.685', 'F04.096.753'], ['E05.796.817', 'F02.830.650', 'F04.669.817', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[A case of pseudomigraine with pleocytosis]. | We report a case of pseudomigraine with pleocytosis (PMP) characterized by temporary neurological deficits and elevated cell counts in cerebrospinal fluid (CSF). A 28-year-old woman was admitted to our hospital with a second episode of right side throbbing headache accompanied by hemianopsia without scintillating scoto... | ['Adult', 'Diagnosis, Differential', 'Female', 'Humans', 'Leukocytosis', 'Migraine Disorders'] | 12,739,386 | [['M01.060.116'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.378.553.475', 'C23.550.526'], ['C10.228.140.546.399.750']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chromosomal heteromorphism linked to the mating type locus of the oomycete Phytophthora infestans. | The mating type locus of the oomycete, Phytophthora infestans, is embedded in a region of DNA that displays distorted and non-Mendelian segregation. By using DNA probes linked to the mating type locus to genetically and physically characterize that region, a large zone of chromosomal heteromorphism was detected. Locus ... | ['Base Sequence', 'Chromosome Mapping', 'Chromosomes, Fungal', 'Crosses, Genetic', 'DNA Primers', 'Electrophoresis, Agar Gel', 'Electrophoresis, Gel, Pulsed-Field', 'Genes, Fungal', 'Genes, Mating Type, Fungal', 'Genetic Markers', 'Molecular Sequence Data', 'Nucleic Acid Hybridization', 'Phytophthora', 'Polymerase Chai... | 8,804,388 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['A11.284.187.360', 'A19.311', 'G05.360.162.360'], ['E05.393.281'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.196.401.153', 'E05.301.300.100'], ['E05.196.401.220', 'E05.301.300.220'], ['G05.360.340.024.340.364.500', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Neuropathological criteria of anti-IgLON5-related tauopathy. | We recently reported a novel neurological syndrome characterized by a unique NREM and REM parasomnia with sleep apnea and stridor, accompanied by bulbar dysfunction and specific association with antibodies against the neuronal cell-adhesion protein IgLON5. All patients had the HLA-DRB1*1001 and HLA-DQB1*0501 alleles. N... | ['Aged', 'Brain', 'Cell Adhesion Molecules, Neuronal', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neurons', 'Tauopathies', 'tau Proteins'] | 27,358,064 | [['M01.060.116.100'], ['A08.186.211'], ['D12.776.395.550.200.250', 'D12.776.543.550.200.250', 'D23.050.301.350.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.675', 'A11.671'], ['C10.574.945'], ['D12.776.220.600.450.510', 'D12.776.631.560.510']] | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation. | Transcription factors carry functional domains, which are often physically distinct, for sequence-specific DNA binding, transcriptional activation and regulatory functions. The transcription factor ATF-2 is a DNA-binding protein that binds to cyclic AMP-response elements (CREs), forms a homodimer or heterodimer with c-... | ['Acetyltransferases', 'Activating Transcription Factor 2', 'Amino Acid Sequence', 'Animals', 'Cyclic AMP Response Element-Binding Protein', 'Enzyme Activation', 'HeLa Cells', 'Histone Acetyltransferases', 'Histones', 'Humans', 'Luciferases', 'Molecular Sequence Data', 'Phosphorylation', 'Recombinant Fusion Proteins', ... | 10,821,277 | [['D08.811.913.050.134'], ['D12.776.260.108.061.750', 'D12.776.930.127.061.750'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['G02.111.263', 'G03.328'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['D08.811.913.050.134.415.500'], ['D12.776... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A gonadotropin-releasing hormone-II antagonist induces autophagy of prostate cancer cells. | Gonadotropin-releasing hormone-I (GnRH-I) is known to directly regulate prostate cancer cell proliferation. However, the role of GnRH-II in prostate cancer is unclear. Here, we investigated the effect of the GnRH-II antagonist trptorelix-1 (Trp-1) on growth of PC3 prostate cancer cells. Trp-1 induced growth inhibition ... | ['Animals', 'Autophagy', 'Caspase 3', 'Cell Growth Processes', 'Cell Line, Tumor', 'Cytochromes c', 'Female', 'Gonadotropin-Releasing Hormone', 'HeLa Cells', 'Humans', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Mitochondria', 'Oligopeptides', 'Prostatic Neoplasms', 'Reactive Oxygen Species'] | 19,176,390 | [['B01.050'], ['G04.011'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['G04.161', 'G07.345.249.410'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.244.286.100', 'D12.776.422.220.286.100'], ['D06.472.699.327.740.320', 'D1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrathin frozen sections. I. Methods and ultrastructural preservation. | A relatively simple method for obtaining ultrathin, frozen sections for electron microscopy has been developed. Tissues, cultured cells, and bacteria may be employed. They are fixed in 1.25-4% glutaraldehyde for 1-4 hr, are washed overnight in buffer at 3 degrees C, and are embedded in 20% thiolated gelatin or pure gel... | ['Animals', 'Bacteriological Techniques', 'Culture Techniques', 'Dimethyl Sulfoxide', 'Histological Techniques', 'Mice', 'Microscopy, Electron', 'Microtomy', 'Rats', 'Staining and Labeling'] | 4,167,504 | [['B01.050'], ['E01.370.225.875.150', 'E05.200.875.150'], ['E05.481.500'], ['D02.886.640.150'], ['E01.370.225.750', 'E05.200.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.402', 'E05.595.402'], ['E01.370.225.500.620.530', 'E01.370.225.750.600.530', 'E05.200.500.620.530', 'E05.200.750.600.530'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bone marrow mesenchymal stem cells suppress IL-9 in adjuvant-induced arthritis. | Interleukin-9 (IL-9) has been shown to be upregulated in rheumatoid arthritis (RA). The exact role of IL-9 has not yet been effectively studied. Mesenchymal stem cells (MSCs) have shown a promising immunomodulatory role towards repairing cartilage and restoring joint function. One of the key problems influencing the th... | ['Allografts', 'Animals', 'Arthritis, Experimental', 'Bone Marrow Cells', 'Hesperidin', 'Interleukin-9', 'Male', 'Mesenchymal Stem Cell Transplantation', 'Mesenchymal Stem Cells', 'Rats'] | 29,359,591 | [['A01.941.500'], ['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['A11.148', 'A15.378.316'], ['D03.383.663.283.266.450.252.500', 'D03.633.100.150.266.450.252.500', 'D09.408.386'], ['D12.644.276.374.465.377', 'D12.776.467.374.465.312', 'D23.529.374.465.377'], ['E02.095.147.500.500.625', 'E04.936.225.687.625'], ['A... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Priming the holiday spirit: persistent activation due to extraexperimental experiences. | The concept of activation is a critical component of many models of cognition. A key characteristic of activation is that recent experience with a concept or stimulus increases the accessibility of the corresponding representation. The extent to which increases in accessibility occur as a result of experiences outside ... | ['Achievement', 'Arousal', 'Association Learning', 'Attention', 'Concept Formation', 'Conflict, Psychological', 'Cues', 'Decision Making', 'Holidays', 'Humans', 'Individuality', 'Mental Recall', 'Motivation', 'Reaction Time', 'Seasons', 'Semantics', 'Time Perception', 'Verbal Learning'] | 19,966,266 | [['F01.658.059', 'F02.784.629.054'], ['F02.830.104', 'G11.561.035'], ['F02.463.425.069.296'], ['F02.830.104.214'], ['F02.463.785.233'], ['F01.658.209'], ['F02.463.425.234'], ['F02.463.785.373'], ['I03.450.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F02.463.425.540.641'], ['F01.658', 'F01.... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
"That's not a beer bong, it's a breast pump!" representations of breastfeeding in prime-time fictional television. | Breastfeeding has been recognized as one of the key determinant in one's future health. Yet although most people are aware of the benefits, many women do not breastfeed their babies past the first few months. These low rates can be partially explained by negative cultural attitudes toward breastfeeding, which have been... | ['Age Factors', 'Breast Feeding', 'Choice Behavior', 'Culture', 'Humans', 'Sex Factors', 'Socioeconomic Factors', 'Television', 'Time Factors'] | 22,746,199 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['F02.463.785.373.346'], ['I01.076.201.450', 'I01.880.853.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N05.715.350.675', 'N06.850.490.875'], ['I01.880.853.996', 'N01.824'], ['J... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
[Effects of N-methyl-D-aspartate receptor in visceral, hypersensitivity in rats with colonic inflammation]. | OBJECTIVE: To investigate the effects of N-methyl-D-aspartate receptor (NMDAR) in the spinal dorsal horn in visceral hypersensitivity in rats with colonic inflammation.METHODS: Seventy adult male Sprague-Dawley (SD) rats were randomly divided into the experimental group and the control group. Colonic inflammation was i... | ['Animals', 'Colitis', 'Male', 'Posterior Horn Cells', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, N-Methyl-D-Aspartate', 'Trinitrobenzenesulfonic Acid'] | 16,320,576 | [['B01.050'], ['C06.405.205.265', 'C06.405.469.158.188'], ['A08.186.854.697.500', 'A08.675.650.675', 'A11.671.650.675'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D12.776.157.530.4... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival. | Neuroblastoma is the most common extracranial solid tumor of childhood and is responsible for over 15% of pediatric cancer deaths. Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that is important in many facets of neuroblastoma tumor development and progression. The p53 oncogene, although wild type in mos... | ['Cell Line, Tumor', 'Cell Survival', 'Focal Adhesion Protein-Tyrosine Kinases', 'Humans', 'Neuroblastoma', 'Tumor Suppressor Protein p53'] | 25,862,488 | [['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D08.811.913.696.620.682.725.049', 'D12.644.360.287', 'D12.776.476.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.600.590.650.550', 'C04.557.470.670.590.650.550', 'C04.557.580.625.600.590.650.550'], ['D12.776.157.687.650', 'D12.776.260.82... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Response to preoperative chemoradiation in stage II and III rectal cancer. | PURPOSE: The purpose of this study was to determine whether a complete pathologic response after neoadjuvant therapy in rectal cancer patients improves disease control and survival.METHODS: The study reviewed Stage II and III rectal cancer patients treated with preoperative chemoradiation and resected for cure. Complet... | ['Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Chemotherapy, Adjuvant', 'Female', 'Fluorouracil', 'Humans', 'Leucovorin', 'Male', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Postoperative Care', 'Preoperative Care', 'Radiotherapy Dosage', 'Radiotherapy, Adjuvant', 'Rectal Neoplasms', 'Survival Analy... | 12,972,962 | [['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186.170', 'E02.319.170'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.733.631.400.800.350.450', 'D08.211.840.300.500'], ['C04.697.655', 'C23.550.727.655'], ['E01.789.625'], ['E02.760.73... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Estimate of serum immunoglobulin G concentration using refractometry with or without caprylic acid fractionation. | Objectives of this study were to develop a rapid calf-side test to determine serum IgG concentrations using caprylic acid (CA) fractionation, followed by refractometry of the IgG-rich supernatant and compare the accuracy of this method with results obtained using refractometry using raw serum. Serum samples (n=200) wer... | ['Acetic Acid', 'Animals', 'Animals, Newborn', 'Caprylates', 'Cattle', 'Centrifugation', 'Chemical Fractionation', 'Colostrum', 'Immunization, Passive', 'Immunodiffusion', 'Immunoglobulin G', 'Refractometry'] | 23,664,346 | [['D02.241.081.018.165', 'D10.251.400.045.500'], ['B01.050'], ['B01.050.050.282'], ['D02.241.081.222', 'D10.251.122'], ['B01.050.150.900.649.313.500.380.271'], ['E05.181'], ['E05.196.155'], ['A12.200.194'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A prospective, randomized comparison of interpleural and paravertebral analgesia in thoracic surgery. | We have undertaken a prospective, randomized comparison of the superficially similar techniques of interpleural and paravertebral (extrapleural) analgesia in 53 patients undergoing posterolateral thoracotomy. Local anaesthetic placed anterior to the superior costotransverse ligament and posterior to the parietal pleura... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Analgesia', 'Anesthetics, Local', 'Bupivacaine', 'Drug Administration Schedule', 'Humans', 'Middle Aged', 'Morphine', 'Pleura', 'Prospective Studies', 'Respiratory Mechanics', 'Single-Blind Method', 'Thoracotomy'] | 7,488,477 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E03.091'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['D02.065.199.239', 'D02.092.146.113.239'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.13... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pathogenic characterization of 1-methyl-1-nitrosourea-induced mammary carcinomas in the rat. | The induction of mammary carcinogenesis in the rat by 1-methyl-1-nitrosourea (MNU) is widely used in experimental breast cancer research. In the experiments reported, the Ha-ras codon 12 (ras12) mutation (GGA-->GAA) was used as a molecular marker to address issues of the clonality of carcinomas induced, pathogenetic in... | ['Animals', 'Carcinogens', 'Codon', 'Female', 'Genes, ras', 'Genotype', 'Mammary Neoplasms, Experimental', 'Methylnitrosourea', 'Mutagenesis', 'Point Mutation', 'Polymerase Chain Reaction', 'Rats', 'Rats, Sprague-Dawley'] | 9,472,716 | [['B01.050'], ['D27.888.569.100'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['G05.360.340.024.340.375.500.791.550'], ['G05.380'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['D02.065.950.594.490', 'D02.654.692.480'], ['G05.558'], ['G05.365.590.675'], ['E05.393.620.500']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of atelectasis and surface tension on pulmonary vascular compliance. | The effects of atelectasis and surface tension on the vascular volume and compliance in an isolated perfused dog lung lobe were studied using vascular occlusion and indicator-dilution methods. Measurements were made during atelectasis and again after the lobes were inflated with either a gas mixture (air) or 0.9% salin... | ['Animals', 'Blood Volume', 'Capillaries', 'Dogs', 'In Vitro Techniques', 'Lung', 'Perfusion', 'Pulmonary Atelectasis', 'Pulmonary Circulation', 'Surface Tension', 'Vascular Resistance'] | 1,885,433 | [['B01.050'], ['G09.188.130', 'G09.330.380.092'], ['A07.015.461.165'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.481'], ['A04.411'], ['E05.680'], ['C08.381.730'], ['G09.330.100.770', 'G09.772.593'], ['G02.860.816'], ['G09.330.380.921']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and structure determination of the adducts formed by electrochemical oxidation of 1,2,3,4-Tetrahydro-7,12-dimethylbenz[a]anthracene in the presence of deoxyribonucleosides or adenine. | Study of DNA adducts formed with aromatic hydrocarbons is part of the strategy to elucidate the mechanisms of tumor initiation by these compounds. 1,2,3,4-Tetrahydro-7,12-dimethylbenz[a]anthracene (THDMBA) is of special interest because it allows discrimination between the pathways of bioactivation by one-electron oxid... | ['9,10-Dimethyl-1,2-benzanthracene', 'Adenine', 'Carcinogens', 'Chromatography, High Pressure Liquid', 'DNA Adducts', 'Deoxyribonucleosides', 'Electrochemistry', 'Magnetic Resonance Spectroscopy', 'Oxidation-Reduction', 'Spectrometry, Mass, Fast Atom Bombardment', 'Spectrophotometry, Ultraviolet'] | 8,951,228 | [['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['D03.633.100.759.138'], ['D27.888.569.100'], ['E05.196.181.400.300'], ['D13.444.308.135', 'G05.200.104'], ['D13.570.230'], ['H01.181.529.307'], ['E05.196.867.519'], ['G02.700', 'G03.295.531'], ['E05.196.566.750'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Research on the transformation of ginsenoside Rg1 by intestinal flora]. | OBJECTIVE: The decomposition of Ginsenoside Rg1(Rg1) by intestinal bacteria in rats or human was investigated both in vitro and in vivo.METHOD: The decompositions were investigated by means of thin-layer chromatography and Electron spurt ion mass.RESULT: It was found that Rg1 was converted into two metabolites [Rh1 and... | ['Animals', 'Bacterial Physiological Phenomena', 'Ginsenosides', 'Humans', 'In Vitro Techniques', 'Intestines', 'Male', 'Rats', 'Rats, Wistar'] | 12,525,040 | [['B01.050'], ['G06.099'], ['D02.455.849.919.277', 'D09.408.782.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A03.556.124'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass. | BACKGROUND: Myostatin negatively regulates skeletal muscle growth. Myostatin knockout mice exhibit muscle hypertrophy and decreased interstitial fibrosis. We investigated whether a plasmid expressing a short hairpin interfering RNA (shRNA) against myostatin and transduced using electroporation would increase local skel... | ['Animals', 'Base Sequence', 'Cell Line', 'Electroporation', 'Gene Expression', 'Gene Silencing', 'Gene Transfer Techniques', 'Genes, Reporter', 'Genetic Vectors', 'Humans', 'Lac Operon', 'Male', 'Mice', 'Muscle, Skeletal', 'Myostatin', 'Plasmids', 'RNA, Small Interfering', 'Rats', 'Rats, Inbred F344', 'Transfection', ... | 16,810,717 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['E05.200.500.454', 'E05.242.448', 'E05.301.500'], ['G05.297'], ['G05.308.203.374'], ['E05.393.350'], ['G05.360.340.024.340.435'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.686.545', 'G05.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pulmonary metastases, an occult prostatic adenocarcinoma and delayed administration of antiandrogens. | The presentation of prostatic carcinoma with pulmonary metastases is unusual. The patient reported here presented with nodular lung metastases from an unknown primary site and 3.5 years later became symptomatic with a prostatic carcinoma. Subsequent hormonal therapy led to radiological regression of the pulmonary metas... | ['Adenocarcinoma', 'Aged', 'Androgen Antagonists', 'Antineoplastic Agents, Hormonal', 'Cyproterone', 'Follow-Up Studies', 'Humans', 'Lung Neoplasms', 'Male', 'Neoplasms, Unknown Primary', 'Prostatic Neoplasms', 'Remission Induction'] | 8,859,611 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['D06.347.065', 'D27.505.696.399.450.065'], ['D27.505.954.248.169'], ['D04.210.500.745.432.219', 'D04.210.500.883.419'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.89... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Potentially inappropriate prescribing cardiovascular medications in the aged population: prospective study in a district hospital centre (France)]. | OBJECTIVES: Cardiovascular disease is a leading cause of morbidity and mortality in the elderly population. We evaluated the adequacy of prescribing (miss and under used) with respect to STOPP-START criteria.METHODS: A sample of 100 patients hospitalized in cardiovascular specialty divisions (medicine or surgery) or in... | ['Aged', 'Aged, 80 and over', 'Cardiovascular Agents', 'Cardiovascular Diseases', 'Comorbidity', 'Female', 'France', 'Hospitalization', 'Hospitals, District', 'Humans', 'Inappropriate Prescribing', 'Male', 'Polypharmacy', 'Prevalence'] | 25,535,164 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.411'], ['C14'], ['N05.715.350.225', 'N06.850.490.687'], ['Z01.542.286'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421.510.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.490', 'N02.421.450.500.249'], ['E02.319.698'], ['E05.318.308.985.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Fractionation and identification of metalloproteins from a marine cyanobacterium. | Trace metals are essential for the growth of marine cyanobacteria, being required for key cellular processes such as photosynthesis and respiration. Despite this, the metalloproteomes of marine cyanobacteria are at present only poorly defined. In this study, we have probed the major cobalt, iron, manganese, and nickel-... | ['Bacterial Proteins', 'Chromatography, Affinity', 'Mass Spectrometry', 'Metalloproteins', 'Molecular Sequence Data', 'Proteomics', 'Seawater', 'Synechococcus'] | 22,258,207 | [['D12.776.097'], ['E05.196.181.400.170'], ['E05.196.566'], ['D12.776.556'], ['L01.453.245.667'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['G16.500.275.725.500'], ['B03.280.745', 'B03.440.475.100.745']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of severe protein-calorie malnutrition on the penetration kinetics of trimethoprim and sulfamethoxazole to the deep tissues of Wistar rats. | This study shows the effect that severe malnourishment has on the kinetics of antibiotic penetration in tissues. A total of 104 male Wistar rats, 21 days old, were randomly divided into eight groups. Five groups of experimental rats were severely malnourished (SM) and three further groups were considered well-nourished... | ['Animals', 'Anti-Infective Agents', 'Chromatography, High Pressure Liquid', 'Dietary Proteins', 'Drug Administration Schedule', 'Injections, Intraperitoneal', 'Kidney', 'Liver', 'Lung', 'Male', 'Malnutrition', 'Rats', 'Rats, Wistar', 'Spleen', 'Trimethoprim, Sulfamethoxazole Drug Combination'] | 12,803,768 | [['B01.050'], ['D27.505.954.122'], ['E05.196.181.400.300'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['E02.319.283'], ['E02.319.267.530.490'], ['A05.810.453'], ['A03.620'], ['A04.411'], ['C18.654.521'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['A10.549.700... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Mechanism of hydrogen peroxide-induced apoptosis of the human osteosarcoma cell line HS-Os-1. | In our previous study, we examined radiation-induced ROS formation, oxidative DNA damage, early apoptotic changes, and mitochondrial membrane dysfunction in the human osteosarcoma cell line HS-Os-1, which was established from an osteoblastic tumor that arose in the left humerus of an 11-year-old girl and was already mo... | ['Annexin A5', 'Apoptosis', 'Cell Line, Tumor', 'Child', 'DNA Damage', 'Dose-Response Relationship, Radiation', 'Female', 'Free Radicals', 'Humans', 'Hydrogen Peroxide', 'Microscopy, Fluorescence', 'Osteosarcoma', 'Oxidative Stress', 'Reactive Oxygen Species'] | 12,964,019 | [['D12.776.157.125.050.100'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['M01.060.406'], ['G05.200'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['D01.339', 'D02.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Treatable ischemic neuronal damage in the gerbil hippocampus]. | The Mongolian gerbil is known to develop delayed neuronal death in the hippocampus following brief forebrain ischemia (Brain Res 239: 57-69). Morphological, biochemical, or electrophysiological studies on this neuronal injury have shown that neurons still retain potential reversibility at the earlier period of alterati... | ['Animals', 'Brain Ischemia', 'Diazepam', 'Gerbillinae', 'Hippocampus', 'Humans', 'Imidazoles', 'Pentobarbital'] | 3,814,442 | [['B01.050'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D03.633.100.079.080.070.216'], ['B01.050.150.900.649.313.992.635.300'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['D03.383.742.698.253.593']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). | INTRODUCTION: The neuropsychological battery of the Uniform Data Set (UDSNB) was implemented in 2005 by the National Institute on Aging (NIA) Alzheimer Disease Centers program to measure cognitive performance in dementia and mild cognitive impairment due to Alzheimer Disease. This paper describes a revision, the UDSNB ... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Cognitive Dysfunction', 'Data Collection', 'Databases, Factual', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neuropsychological Tests'] | 29,240,561 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['F03.615.250.700'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Congenital disability and medical research: the development of amniocentesis. | The action imperative inherent in amniocentesis, one that emphasizes the detection and selective abortion of disabled fetuses, exerts a powerful influence on women's decisions to undergo prenatal diagnosis. In this paper, the construction of this imperative is considered through an examination of medical research that ... | ['Abortion, Therapeutic', 'Amniocentesis', 'Congenital Abnormalities', 'Female', 'Human Rights', 'Humans', 'Prenatal Diagnosis', 'Research', 'Social Values', "Women's Rights"] | 2,267,804 | [['E04.520.050.060'], ['E01.370.225.500.384.050', 'E01.370.225.998.329.309', 'E01.370.378.630.050', 'E04.665.600.309', 'E05.200.500.384.050', 'E05.200.998.329.309', 'E05.242.384.050'], ['C16.131'], ['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.378.630'], ['H01.770.644'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
The phenomenology of autistic regression: subtypes and associated factors. | This study aimed to investigate the association of autistic regression (AR) and subtypes of AR with medical, developmental and psychiatric factors. Fifty-seven children with autistic spectrum disorders (ASD) were included in the study. Two types of AR are defined as regression after a normal social/language development... | ['Adolescent', 'Child', 'Child Development Disorders, Pervasive', 'Child, Preschool', 'Female', 'Gastrointestinal Diseases', 'Humans', 'Learning', 'Male', 'Psychiatric Status Rating Scales', 'Regression, Psychology', 'Sex Factors', 'Sleep Wake Disorders', 'Wechsler Scales'] | 22,080,249 | [['M01.060.057'], ['M01.060.406'], ['F03.625.164'], ['M01.060.406.448'], ['C06.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['F04.711.513.653'], ['F01.393.784'], ['N05.715.350.675', 'N06.850.490.875'], ['C10.886', 'C23.888.592.796', 'F03.870'], ['F04.711.141.493.822']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Role of the liver in small-solute transport during peritoneal dialysis. | Peritoneal dialysis (PD) is dependent on the transport of water and solutes from the blood capillaries within the tissues that surround the peritoneal cavity. Because of their large blood supply and surface area, the viscera have been considered the most important tissues for PD transport. In animals, however, removal ... | ['Abdominal Muscles', 'Adult', 'Animals', 'Body Fluid Compartments', 'Diaphragm', 'Humans', 'Liver', 'Models, Biological', 'Molecular Weight', 'Peritoneal Cavity', 'Peritoneal Dialysis', 'Sucrose', 'Viscera'] | 7,948,778 | [['A02.633.567.050'], ['M01.060.116'], ['B01.050'], ['A10.082', 'A12.207.180'], ['A02.633.567.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E05.599.395'], ['G02.494'], ['A01.923.047.025.600.678'], ['E02.870.300.650', 'E02.912.800.650'], ['D09.698.629.305.770', 'D09.947.750.770'], ['A01.960'... | ['Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Acute non-herpetic viral encephalitis of juvenile onset: analysis of 11 cases based on initial clinical symptoms]. | We investigated clinical features of juvenile patients presenting non-herpetic viral acute encephalitis (4 men and 7 women, aged of onset; 23.7 +/- 3.3 years) without malignancy and immunodeficiency. We divided the patients into two groups according to initial neurological symptoms: psychiatric symptoms mimicking schiz... | ['Acute Disease', 'Adolescent', 'Adult', 'Brain', 'Diagnosis, Differential', 'Dyskinesias', 'Encephalitis, Viral', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Prognosis', 'Schizophrenia', 'Seizures'] | 16,095,221 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['E01.171'], ['C10.228.662.262', 'C10.597.350', 'C23.888.592.350'], ['C01.207.245.340', 'C01.207.399.750', 'C01.925.182.525', 'C10.228.140.430.520.750', 'C10.228.228.245.340', 'C10.228.228.399.750'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enriched environment inhibits mouse pancreatic cancer growth and down-regulates the expression of mitochondria-related genes in cancer cells. | Psycho-social stress has been suggested to influence the development of cancer, but it remains poorly defined with regard to pancreatic cancer, a lethal malignancy with few effective treatment modalities. In this study, we sought to investigate the impacts of enriched environment (EE) housing, a rodent model of "eustre... | ['Animals', 'Cell Proliferation', 'Disease Models, Animal', 'Environment', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Mice', 'Mitochondrial Proteins', 'Oxidative Phosphorylation', 'Pancreatic Neoplasms', 'Proteomics', 'RNA, Messenger', 'Xenograft Model Antitumor Assays'] | 25,598,223 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G16.500.275', 'N06.230'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.575'], ['G02.111.665.550', 'G03.295.631', 'G03.796.550'], ['C04.588.27... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The alpha-subunit mRNAs for Gs and Go2 are differentially regulated by protein kinase A and protein kinase C in rat Sertoli cells. | In the present study, we have examined regulatory effects of protein kinase A and protein kinase C activation by 8-CPTcAMP and TPA, respectively, on mRNAs for various G protein alpha-subunits and corresponding immunoreactive proteins in rat Sertoli cells. Gs alpha and Go alpha mRNA levels were transiently increased 1.5... | ['Animals', 'Cells, Cultured', 'Cyclic AMP', 'Cyclic AMP-Dependent Protein Kinases', 'GTP-Binding Proteins', 'Male', 'Protein Kinase C', 'Protein Synthesis Inhibitors', 'RNA, Messenger', 'Rats', 'Sertoli Cells', 'Tetradecanoylphorbol Acetate', 'Thionucleotides'] | 7,873,600 | [['B01.050'], ['A11.251'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['D08.811.913.696.620.682.700.725'], ['D27.505.519.389.760']... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differences between smokers and never-smokers in sensitivity to nicotine: a preliminary report. | Sensitivity to nicotine was explored using test doses administered via intra-nasal aerosol in 10 smokers and 10 never-smokers. Smokers received 1.50 mg nicotine (in 2 sprays, < 5 seconds apart, one spray per nostril); never-smokers received either 0.50 mg (n = 3) or 0.25 mg (n = 7) nicotine. Accumulation of nicotine in... | ['Administration, Intranasal', 'Adult', 'Aerosols', 'Arousal', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Humans', 'Male', 'Nicotine', 'Smoking'] | 8,448,500 | [['E02.319.267.120.655.500'], ['M01.060.116'], ['D20.280.055', 'D26.255.165.055'], ['F02.830.104', 'G11.561.035'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.760.570', 'D03.383.725.518'], ['F01.145.805']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Xanthic variant of non-ossifying fibroma (so-called xanthofibroma) of the mandible. An ultrastructural study. | An unusual case of a 37-year-old female with xanthomatous bone tumor of the right molar area of the mandible was presented. The tumor was asymptomatic and found to be a well-demarcated intraosseous radiolucent lesion on radiographic examination. Histologically the tumor consisted of two cell types, fibroblastic and xan... | ['Adult', 'Female', 'Fibroma', 'Humans', 'Mandibular Neoplasms', 'Staining and Labeling'] | 6,176,096 | [['M01.060.116'], ['C04.557.450.565.590.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.149.721.450.583', 'C05.116.231.754.450.583', 'C05.500.499.583', 'C05.500.607.442', 'C07.320.515.583', 'C07.320.610.583'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.6... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of waiting time on the quality of life of patients awaiting coronary artery bypass grafting. | BACKGROUND: A lack of resources has created waiting lists for many elective surgical procedures within Canada's universal health care system. Coronary artery bypass grafting (CABG) for the treatment of atherosclerotic ischemic heart disease is one of these affected surgical procedures. We studied the impact of waiting ... | ['Comorbidity', 'Coronary Artery Bypass', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Quality of Life', 'Quebec', 'Stress, Psychological', 'Time Factors', 'Waiting Lists'] | 11,531,051 | [['N05.715.350.225', 'N06.850.490.687'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['I01.800', 'K01.752.400.750',... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Elective laparoscopic cholecystectomy for symptomatic gallstone disease in patients receiving anticoagulant therapy. | BACKGROUND: The safety of laparoscopic cholecystectomy (LC) has been proven in patients with several pre-existing clinical conditions. This study was conducted to evaluate the applicability and safety of elective LC in patients with pre-existing cardiovascular conditions who were receiving anticoagulant treatment.PATIE... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anticoagulants', 'Cardiovascular Diseases', 'Case-Control Studies', 'Chi-Square Distribution', 'Cholecystectomy, Laparoscopic', 'Female', 'Gallstones', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Statistics, Nonparametric', 'Treatment Outcome'] | 16,108,736 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.502.119'], ['C14'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E04.210.120.172.140', 'E04.502.250.520.160'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis of bromo-conduritol-B and bromo-conduritol-C as glycosidase inhibitors. | For the synthesis of bromo-conduritol-B skeleton, bromo-1,4-benzoquinone was subjected to bromination followed by the reduction of the carbonyl groups with NaBH(4). Substitution of bromides bonded to sp(3)-hybridized carbon atoms with AgOAc gave the bromo-conduritol-B tetraacetate in high yield. For the construction of... | ['Bromine', 'Enzyme Inhibitors', 'Glycoside Hydrolases', 'Inositol', 'Magnetic Resonance Spectroscopy', 'Molecular Structure'] | 19,121,824 | [['D01.268.380.112'], ['D27.505.519.389'], ['D08.811.277.450'], ['D02.033.800.519', 'D09.853.519'], ['E05.196.867.519'], ['G02.111.570', 'G02.466']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Putting the methodological brakes on claims to measure national happiness through Twitter: Methodological limitations in social media analytics. | With the rapid global proliferation of social media, there has been growing interest in using this existing source of easily accessible 'big data' to develop social science knowledge. However, amidst the big data gold rush, it is important that long-established principles of good social research are not ignored. This a... | ['Happiness', 'Humans', 'Social Media', 'Social Sciences'] | 28,880,882 | [['F01.470.516'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.751', 'L01.224.230.110.500.750'], ['F04.096.879', 'I01']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Platelet prostaglandin E1 hyposensitivity in schizophrenia: decrease in cyclic AMP formation and in inhibitory effects on aggregation. | Cyclic adenosine monophosphate (cAMP) formation via prostaglandin E1 (PGE1) or forskolin stimulation was determined in washed platelets from 35 schizophrenic patients and 34 normal controls. The inhibitory effects of PGE1 and forskolin on platelet aggregation response (PAR) elicited by adenosine diphosphate (ADP) were ... | ['Adult', 'Blood Platelets', 'Colforsin', 'Cyclic AMP', 'Female', 'Humans', 'Male', 'Middle Aged', 'Platelet Aggregation Inhibitors', 'Prostaglandins E', 'Schizophrenia'] | 2,177,206 | [['M01.060.116'], ['A11.118.188', 'A15.145.229.188'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D27.505.954.502.780'], ['D10.251.355.255.550.250', 'D23.469.050.175.725... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A study into bacteriological positivity and treatment of beggar leprosy patients. | Hundred beggar leprosy patients were medically examined and skin smears were taken for bacteriological positivity for A.F.B. Information regarding their treatment was collected. 20% of them were found bacteriologically positive and 40% of the positive cases were not taking treatment. Epidemiological and operational imp... | ['Biopsy', 'Dapsone', 'Homeless Persons', 'Humans', 'India', 'Leper Colonies', 'Leprosy', 'Skin'] | 2,746,032 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D02.886.590.263'], ['M01.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['N02.278.524'], ['C01.150.252.410.040.552.475.371'], ['A17.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Effects of angiotensin-induced hypertension on cancer chemotherapy. Application to intra-arterial infusion chemotherapy for advanced breast cancer]. | In an attempt to enhance effects of cancer chemotherapy, Angiotensin II (AT), a vasoconstricting catecholamine, was applied to intra-arterial infusion of the drug for advanced breast cancer. Quantitative measurement of tumor blood flow was conducted with scintigraphic techniques (81mKr). Angiotensin II given continuous... | ['Aged', 'Angiotensin II', 'Blood Pressure', 'Breast Neoplasms', 'Doxorubicin', 'Drug Therapy, Combination', 'Female', 'Humans', 'Infusions, Intra-Arterial', 'Middle Aged'] | 6,870,306 | [['M01.060.116.100'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C04.588.180', 'C17.800.090.500'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Efficacy of Yeast' Vacuoles as Antimicrobial Agents to Escherichia coli Bacteremia in Rat. | Yeast vacuoles, lysosomes, are cell organelles that have antimicrobial activity against several bacteria in vitro. Lysosomes have a potential application to the treatment of pathogens such as antibiotics in vivo. Therefore, the in vivo efficacy of lysosomes was examined in a rat infection model against pathogenic Esche... | ['Animals', 'Anti-Bacterial Agents', 'Bacteremia', 'Disease Models, Animal', 'Escherichia coli', 'Escherichia coli Infections', 'Humans', 'Lysosomes', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Saccharomyces cerevisiae', 'Vacuoles'] | 27,757,529 | [['B01.050'], ['D27.505.954.122.085'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.190.550'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Initiation patterns of statin therapy among adult patients undergoing intermediate to high-risk non-cardiac surgery. | BACKGROUND: A growing body of literature has been produced on the potential role of statins in reducing perioperative cardiac events in patients undergoing non-cardiac surgery. However, evidence remains inconsistent, and little is known about the patterns of perioperative statin use in routine care.OBJECTIVES: The obje... | ['Adolescent', 'Adult', 'Aged', 'Cardiovascular Diseases', 'Cohort Studies', 'Drug Administration Schedule', 'Drug Utilization', 'Elective Surgical Procedures', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Logistic Models', 'Male', 'Middle Aged', 'Perioperative Care', 'United States', 'Young A... | 26,494,361 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.319.283'], ['N04.452.706.477'], ['E04.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Handheld optical coherence tomography scanner for primary care diagnostics. | The goal of this study is to develop an advanced point-of-care diagnostic instrument for use in a primary care office using handheld optical coherence tomography (OCT). This system has the potential to enable earlier detection of diseases and accurate image-based diagnostics. Our system was designed to be compact, port... | ['Animals', 'Equipment Design', 'Humans', 'Image Processing, Computer-Assisted', 'Point-of-Care Systems', 'Primary Health Care', 'Rats', 'Tomography, Optical Coherence', 'Video Recording'] | 21,134,801 | [['B01.050'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['N04.452.442.452.452.680', 'N04.452.515.360.652', 'N04.590.874'], ['N04.590.233.727'], ['B01.050.150.900.649.313.992.635.505.700'], ['E01.370.350.589.249.500', 'E01.370.350.825.805.500', 'E05.642.249.500'], ['L01.280.960']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Does articulation contribute to modifications of postural control during dual-task paradigms? | Many studies have been carried out to investigate the attentional resources required for postural control, using a 'dual-task' methodology in which performance on mental and postural control tasks is compared when these are carried out separately and concurrently. Most mental tasks used in these dual-task studies have ... | ['Adult', 'Attention', 'Heart Rate', 'Humans', 'Movement', 'Postural Balance', 'Posture', 'Psychomotor Performance', 'Respiratory Mechanics', 'Vision, Ocular'] | 12,706,223 | [['M01.060.116'], ['F02.830.104.214'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G11.561.790.541.595'], ['G11.427.695'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['G09.772.705.700'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[A case of high-age minimal change nephrotic syndrome relapse after 18-year remission and effective treatment with steroid and cyclosporin combined therapy]. | We describe the clinical course of a 69-year-old woman, who suffered from minimal change nephrotic syndrome(MCNS) after long-term remission. In 1979, she was admitted to Kanazawa University Hospital due to MCNS verified by renal biopsy and was treated with oral prednisolone(initially 40 mg/day) for two years. She suffe... | ['Administration, Oral', 'Aged', 'Cyclosporine', 'Female', 'Humans', 'Methylprednisolone', 'Nephrosis, Lipoid', 'Prednisolone', 'Pulse Therapy, Drug', 'Recurrence', 'Remission Induction', 'Time Factors', 'Treatment Outcome'] | 11,195,400 | [['E02.319.267.100'], ['M01.060.116.100'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.432.769.795.539'], ['C12.777.419.630.477', 'C13.351.968.419.630.477'], ['D04.210.500.745.432.769.795'], ['E02.319.283.600'], ['C23.550.291.937'], ['E02.860'], ['G... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cyclooxygenase activity contributes to the monoaminergic damage caused by serial exposure to stress and methamphetamine. | Methamphetamine (Meth) is a widely abused psychostimulant that causes long-term dopamine (DA) and serotonin (5-HT) depletions. Stress and Meth abuse are comorbid events in society and stress exacerbates Meth-induced monoaminergic terminal damage. Stress is also known to produce neuroinflammation. This study examined th... | ['Analysis of Variance', 'Animals', 'Biogenic Monoamines', 'Body Temperature', 'Central Nervous System Stimulants', 'Chromatography, High Pressure Liquid', 'Corpus Striatum', 'Disease Models, Animal', 'Gene Expression Regulation', 'Hippocampus', 'Hydrazines', 'Male', 'Methamphetamine', 'Oxazepines', 'Prostaglandin-Endo... | 23,643,743 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D02.092.211.215'], ['E01.370.600.875.374', 'G07.110'], ['D27.505.696.282', 'D27.505.954.427.220'], ['E05.196.181.400.300'], ['A08.186.211.200.885.287.249.487'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.308'], ['A08.186.211.18... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Chronic nicotine treatment eliminates asymmetry in striatal glucose utilization following unilateral transection of the mesostriatal dopamine pathway in rats. | Partial hemitransection was performed through a knife lesion at the meso-diencephalic level in rats to sever the mesostriatal dopamine system. During the subsequent 2 weeks the animals received 0.125 mg/kg/h of nicotine continuously via an osmotic minipump implanted s.c. To achieve prompt high nicotine levels, 4 i.p. i... | ['Animals', 'Caudate Nucleus', 'Chromatography, Gas', 'Corpus Striatum', 'Cotinine', 'Denervation', 'Deoxyglucose', 'Dopamine', 'Glucose', 'Male', 'Nicotine', 'Rats', 'Rats, Inbred Strains'] | 2,812,507 | [['B01.050'], ['A08.186.211.200.885.287.249.487.550.184'], ['E05.196.181.349'], ['A08.186.211.200.885.287.249.487'], ['D03.383.773.812.180'], ['E04.525.210'], ['D09.254.229'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D09.947.875.359.448'], ['D03.132.760.570', 'D03.383.725.518... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aortic Pseudoaneurysm Causing Compression of the Left Main Coronary Artery. | A 75-year-old man with a history of mechanical aortic valve replacement with aortic conduit for severe aortic insufficiency underwent routine screening computed tomography evaluation revealing right coronary anastomosis endoleak and proximal aortic root pseudoaneurysm. | ['Aged', 'Aneurysm, False', 'Aortic Aneurysm, Thoracic', 'Blood Vessel Prosthesis Implantation', 'Coronary Angiography', 'Coronary Occlusion', 'Echocardiography', 'Humans', 'Male', 'Tomography, X-Ray Computed'] | 30,279,298 | [['M01.060.116.100'], ['C14.907.055.090'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['E04.100.814.868.500', 'E04.650.200'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.272', 'C14.907.585.250.272'], ['E01.370.350.130.750', 'E01.370.350.850.22... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Multiple epiphyseal separations in a child with cerebral palsy and scurvy]. | Scurvy is a dietary disease due to Vitamin C deficiency. Vitamin C is related to collagen synthesis and metabolism. Malnutrition, problems in bowel absorption, alcoholism and cerebral palsy are clearly often linked with scurvy, even it is no more common in the industrialized countries. Its clinical features are: asthen... | ['Bone Diseases', 'Cerebral Palsy', 'Child', 'Epiphyses', 'Female', 'Humans', 'Scurvy'] | 19,752,853 | [['C05.116'], ['C10.228.140.140.254'], ['M01.060.406'], ['A02.835.232.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.454.800', 'C15.378.463.515.800', 'C18.654.521.500.133.115.661']] | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Echocardiographic evaluation of the ductal morphology in patients with refractoriness to lipo-prostaglandin E1 therapy. | BACKGROUND: Lipo-prostaglandin (PG)E1 is effective at lower doses and has fewer side effects than PGE1-cyclodextrin (CD). Previous studies, however, have suggested that some patients show refractoriness to lipo-PGE1 in the course of treatment. The present paper examines: (i) whether such cases can be predicted by exami... | ['Alprostadil', 'Drug Resistance', 'Ductus Arteriosus', 'Echocardiography', 'Heart Defects, Congenital', 'Humans', 'Vasodilator Agents'] | 10,804,727 | [['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['G07.690.773.984'], ['A07.541.278.395', 'A16.378.303.395'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis of lymph node metastasis factors in papillary thyroid microcarcinoma]. | OBJECTIVE: To analyze the factors of lymph node metastasis in papillary thyroid microcarcinoma and to evaluate the significance of the selective neck dissection.METHOD: Records of 82 patients with papillary thyroid microcarcinoma were retrospectively analyzed. Sixty patients were received a selective neck dissection (G... | ['Adenocarcinoma, Papillary', 'Adult', 'Aged', 'Female', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neck Dissection', 'Retrospective Studies', 'Thyroid Neoplasms', 'Young Adult'] | 17,969,517 | [['C04.557.470.200.025.085'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E04.446.318', 'E04.580.411'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Event-related potentials when identifying or color-naming threatening schematic stimuli in spider phobic and non-phobic individuals. | BACKGROUND: Previous studies revealed increased parietal late positive potentials (LPPs) in response to spider pictures in spider phobic individuals. This study searched for basic features of fear-relevant stimuli by investigating whether schematic spider images are sufficient to evoke differential behavioral as well a... | ['Adult', 'Animals', 'Color', 'Evoked Potentials', 'Evoked Potentials, Visual', 'Fear', 'Female', 'Humans', 'Male', 'Parietal Lobe', 'Phobic Disorders', 'Spiders', 'Visual Perception'] | 16,981,991 | [['M01.060.116'], ['B01.050'], ['G01.590.540.199'], ['G07.265.216.500', 'G11.561.200.500'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.200.885.287.500.670'], ['F03.080.725'], ['B01.050.500.131.166.803'], ['F02.463.593.932']] | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Influence of Ureaplasma urealyticum infection on the sperm-egg binding associated molecule, sulfogalactosylglycerolipid]. | OBJECTIVE: To study the influence of Ureaplasma urealyticum (Uu) infection on the sperm-egg binding associated molecule, sulfogalactosylglycerolipid (SGG).METHODS: Epididymal sperm was collected from adult mice. The sperm suspension was randomly divided into 4 groups: Uu group (coincubated with Uu suspension), medium g... | ['Animals', 'Cell Membrane', 'Galactolipids', 'Infertility, Male', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Random Allocation', 'Sperm-Ovum Interactions', 'Spermatozoa', 'Ureaplasma Infections', 'Ureaplasma urealyticum'] | 15,497,702 | [['B01.050'], ['A11.284.149'], ['D09.400.410.209', 'D10.390.355'], ['C12.294.365.700'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['G08.686.784.277... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Demographics, presentation, and clinical outcomes after traumatic bifrontal contusions: a systematic review. | Traumatic bifrontal contusions (TBC) form a recognised clinical entity among patients with traumatic brain injury (TBI). This study aims to systematically review current literature on demographics, management, and predictors of outcomes of patients with TBC. A multi-database literature search (PubMed, Cochrane, OVID Me... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Brain Injuries', 'Brain Injuries, Traumatic', 'Child', 'Contusions', 'Demography', 'Humans', 'Male', 'Middle Aged', 'Young Adult'] | 31,098,790 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['C10.228.140.199.444', 'C10.900.300.087.235', 'C26.915.300.200.194'], ['M01.060.406'], ['C26.974.250'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
NLS-Cholic Acid Conjugation to IL-5Rá-Specific Antibody Improves Cellular Accumulation and In Vivo Tumor-Targeting Properties in a Bladder Cancer Model. | Receptor-mediated internalization followed by trafficking and degradation of antibody-conjugates (ACs) via the endosomal-lysosomal pathway is the major mechanism for delivering molecular payloads inside target tumor cells. Although a mainstay for delivering payloads with clinically approved ACs in cancer treatment and ... | ['Animals', 'Cell Line, Tumor', 'Cholic Acid', 'Copper Radioisotopes', 'Drug Delivery Systems', 'Humans', 'Immunoconjugates', 'Interleukin-5 Receptor alpha Subunit', 'Mice, Inbred NOD', 'Mice, SCID', 'Positron-Emission Tomography', 'Tissue Distribution', 'Urinary Bladder Neoplasms'] | 29,433,309 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D04.210.500.105.225.130', 'D04.210.500.221.430.130'], ['D01.496.749.270'], ['E02.319.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.790.651.114.580', 'D12.776.377.715.548.114.580', 'D27.888.569.257'], ['D12.776.543.750.705.852.420.380.750'],... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Feasibility of a left atrial electrical disconnection procedure for atrial fibrillation using transcatheter radiofrequency ablation. | INTRODUCTION: An effective, catheter-based treatment for persistent atrial fibrillation (AF) remains elusive. This study assessed the feasibility of transcatheter left atrial (LA) electrical disconnection and its effect on AF inducibility.METHOD AND RESULTS: Thirteen anesthetized swine underwent noncontact mapping of t... | ['Animals', 'Atrial Fibrillation', 'Body Surface Potential Mapping', 'Catheter Ablation', 'Coronary Vessels', 'Disease Models, Animal', 'Feasibility Studies', 'Heart Atria', 'Heart Conduction System', 'Heart Septum', 'Models, Cardiovascular', 'Necrosis', 'Swine', 'Treatment Outcome'] | 11,761,416 | [['B01.050'], ['C14.280.067.198', 'C23.550.073.198'], ['E01.370.370.380.240.850.100', 'E01.370.405.240.850.100'], ['E02.808.750.500', 'E04.014.760.500'], ['A07.015.114.269', 'A07.015.908.194'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Multi- and Unifocal Thyroid Microcarcinoma: Are There Any Differences? | BACKGROUND: Thyroid microcarcinoma (TMC) often occurs as two or more separate foci, therefore a completion of primary surgery might be necessary.OBJECTIVES: To evaluate and compare the incidence, diagnostic accuracy, clinicopathological characteristics and surgical treatment of unifocal and multifocal thyroid microcarc... | ['Adult', 'Aged', 'Biopsy, Fine-Needle', 'Female', 'Humans', 'Logistic Models', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Retrospective Studies', 'Thyroid Gland', 'Thyroid Neoplasms', 'Thyroidectomy'] | 27,629,737 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Relation of depressive symptoms to the structure of self-knowledge in childhood. | Measures of positive, negative, and total self-complexity (or self-concept differentiation), self-compartmentalization, self-reported negative events, and self-reported symptoms of depression, anxiety, and conduct disorder were completed by 4th-, 6th-, and 8th-grade public school students. Measures of self-complexity a... | ['Adolescent', 'Anxiety', 'Awareness', 'Child', 'Child Behavior Disorders', 'Depressive Disorder', 'Female', 'Humans', 'Life Change Events', 'Male', 'Personality Development', 'Personality Inventory', 'Psychometrics', 'Self Concept'] | 8,952,186 | [['M01.060.057'], ['F01.470.132'], ['F02.463.188.150'], ['M01.060.406'], ['F03.625.141'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['F01.752.747'], ['F04.711.647.513'], ['F04.711.780'], ['F01.752.747.792']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prospection, Perseverance, and Insight in Sequential Behavior. | Real-world decisions have benefits occurring only later and dependent on additional decisions taken in the interim. We investigated this in a novel decision-making task in humans (n = 76) while measuring brain activity with fMRI (n = 24). Modeling revealed that participants computed the prospective value of decisions: ... | ['Adult', 'Cerebral Cortex', 'Decision Making', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Nerve Net', 'Photic Stimulation', 'Psychomotor Performance', 'Reaction Time', 'Young Adult'] | 30,189,202 | [['M01.060.116'], ['A08.186.211.200.885.287.500'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.511'], ['E05.723.729'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['M01.060.116.815']] | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inverse gas chromatography: considerations about appropriate use for amorphous and crystalline powders. | The use of inverse gas chromatography to assess surface properties of a range of pharmaceutical powders was examined. The powders were two sources of hydroxy propylmethyl cellulose (HPMC), microcrystalline cellulose, magnesium stearate, and acyclovir. These were selected to cover a range for properties from amorphous t... | ['Acyclovir', 'Cellulose', 'Chemical Phenomena', 'Chemistry, Physical', 'Chromatography, Gas', 'Crystallization', 'Excipients', 'Hypromellose Derivatives', 'Methylcellulose', 'Powders', 'Pressure', 'Solubility', 'Stearic Acids', 'Surface Properties', 'Time Factors', 'Water'] | 12,761,817 | [['D03.633.100.759.758.399.454.250'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['G02'], ['H01.181.529'], ['E05.196.181.349'], ['E05.196.300', 'G02.171'], ['D26.650.700.419', 'D27.720.744.770.419'], ['D05.750.078.562.180.357', 'D09.698.365.180.455', 'D25.720.099.500.719',... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
'It's caveman stuff, but that is to a certain extent how guys still operate': men's accounts of masculinity and help seeking. | It is often assumed that men are reluctant to seek medical care. However, despite growing interest in masculinity and men's health, few studies have focussed on men's experiences of consultation in relation to their constructions of masculinity. Those that have are largely based on men with diseases of the male body (t... | ['Adolescent', 'Adult', 'Aged', 'Communication', 'Focus Groups', 'Gender Identity', 'Health Behavior', 'Humans', 'Interpersonal Relations', 'Male', 'Men', 'Middle Aged', 'Narration', 'Patient Acceptance of Health Care', 'Qualitative Research', 'Scotland', 'Sex Factors', 'Stereotyping'] | 15,899,311 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.145.209', 'L01.143'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Protective effect of phosphorylated Hsp27 in coronary arteries through actin stabilization. | There is evidence for an inverse association between cellular expression of Hsp27 and vascular disease with carotid plaques, endarterectomy specimens, and cardiac biopsies investigated to date. Here we compare non-diseased coronary arteries from human heart transplant donors and patients with dilated cardiomyopathy (DC... | ['Actins', 'Biomarkers', 'Coronary Artery Disease', 'Coronary Vessels', 'Electrophoresis, Gel, Two-Dimensional', 'HSP27 Heat-Shock Proteins', 'Humans', 'Myocardial Ischemia', 'Phosphorylation', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'] | 20,600,103 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D23.101'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A07.015.114.269', 'A07.015.908.194'], ['E05.196.401.250', 'E05.301.300.230'], ['D12.776.580.216.270.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gas-chromatographic assay for thiopental in plasma, with use of a nitrogen-specific detector. | An accurate, sensitive, and specific gas-liquid-chromatographic procedure is described for determining concentrations of thiopental in human plasma. After a double extraction of 0.2 or 1.0 mL of plasma containing phenobarbital as an internal standard, thiopental and the internal standard are derivatized in a polar non-... | ['Blood Chemical Analysis', 'Chromatography, Gas', 'Humans', 'Nitrogen', 'Reference Standards', 'Thiopental'] | 7,449,092 | [['E01.370.225.124.100', 'E05.200.124.100'], ['E05.196.181.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.604', 'D01.362.625'], ['E05.978.808'], ['D03.383.742.698.253.800.810']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Proton magnetic resonance spectroscopy of small regions (1 mL) localized inside superficial human tumors. A clinical feasibility study. | It is demonstrated that the stimulated echo technique for proton magnetic resonance spectroscopy (MRS) can be used to study metabolites in volumes of interest (VOIs) as small as 1 mL localized within superficial human tumors. Access to these small VOIs is important for characterization of tissue regions within a tumor,... | ['Carcinoma, Squamous Cell', 'Feasibility Studies', 'Head and Neck Neoplasms', 'Humans', 'Lymphatic Metastasis', 'Magnetic Resonance Imaging', 'Magnetic Resonance Spectroscopy', 'Male', 'Middle Aged', 'Protons'] | 1,963,074 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E01.370.350.825.500'], ['E05.196.867.519'], ['M01.060.116.630'], ['D01.248.49... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of sleep loss on delta (0.3-3 Hz) EEG and eye movement density: new observations and hypotheses. | One night's sleep loss in young adults increased delta (0.3-3 Hz) EEG only in the first non-REM period of recovery sleep. The delta increase was limited to frequencies 0.3-4 Hz; within this range, the effects on wave form periods and amplitudes differed by frequency band. These results illustrate the value of computer ... | ['Adult', 'Brain', 'Electroencephalography', 'Eye Movements', 'Humans', 'Male', 'Sleep Deprivation', 'Sleep, REM'] | 2,441,955 | [['M01.060.116'], ['A08.186.211'], ['E01.370.376.300', 'E01.370.405.245'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.886.425.175', 'C23.888.592.796.772', 'F02.830.855.671', 'F03.870.400.099'], ['F02.830.855.796.671', 'G11.561.803.754.671']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of fluid bolus administration rates using ruggedized field intravenous systems. | OBJECTIVE: The purpose of this study was to evaluate 2 ruggedized field intravenous (IV) systems currently in use by US military medics and to determine their effect on fluid bolus administration rates.METHODS: A series of 500 mL fluid boluses consisting of either Lactated Ringer's solution or Hextend were delivered to... | ['Fluid Therapy', 'Humans', 'Isotonic Solutions', 'Military Medicine', "Ringer's Lactate"] | 24,631,229 | [['E02.319.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.776.498'], ['H02.403.500'], ['D26.776.498.500.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Antibodies against specific membrane proteins of neurosecretory granules isolated from bovine neural lobes. | Membrane proteins from bovine neurosecretory granules isolated by density gradient centrifugation were separated by polyacrylamide gel electrophoresis. A doublet of 120 kDa and and 67 kDa bands were identified as specific proteins of the neurosecretory granule membrane. Antibodies against the 120 kDa doublet were raise... | ['Animals', 'Antibodies', 'Cattle', 'Cell Fractionation', 'Cytoplasmic Granules', 'Hypothalamo-Hypophyseal System', 'Immunohistochemistry', 'Membrane Proteins', 'Pituitary Gland, Posterior', 'Rabbits', 'Rats', 'Supraoptic Nucleus'] | 2,725,945 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['B01.050.150.900.649.313.500.380.271'], ['E05.242.251'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.200.317.357.352.435', 'A08.713.357'], ['E... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Sequence and expression divergence of the AOC gene family in soybean: insights into functional diversity for stress responses. | As a signaling molecule, jasmonate plays a crucial role in orchestrating plant defense responses to a variety of biotic and abiotic stresses. Allene oxide cyclase (AOC: EC5.3.99.6) catalyzes the most important step in the jasmonate biosynthesis pathway. Six AOC genes were isolated from soybean, randomly distributed on ... | ['Biosynthetic Pathways', 'DNA, Plant', 'Gene Expression Profiling', 'Gene Order', 'Genetic Variation', 'Intramolecular Oxidoreductases', 'Molecular Sequence Data', 'Multigene Family', 'Phylogeny', 'Plants, Genetically Modified', 'Sequence Analysis, DNA', 'Sequence Homology', 'Soybeans', 'Tobacco'] | 21,626,009 | [['G02.111.098', 'G03.493.100'], ['D13.444.308.435'], ['E05.393.332'], ['G05.340'], ['G05.365'], ['D08.811.399.475'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B01.650.520', 'B05.620.600'], ['E05.393.760.700'], ['G02.111.810', 'G05.810'], ['B01.650.940.800.575.912.25... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Severe Charcot-Marie-Tooth disease type 1E caused by a novel p.Phe84Leufs*24 PMP22 point mutation. | We report a severe phenotype of Charcot-Marie-Tooth (CMT) disease type 1E caused by a novel p.Phe84Leufs*24 PMP22 point mutation. Ultrastructural examination of a nerve biopsy showed non- or partly myelinated axons which were surrounded by "onion bulb" formations mainly composed of concentric basement membranes and cha... | ['Adult', 'Charcot-Marie-Tooth Disease', 'Humans', 'Male', 'Microscopy, Electron, Transmission', 'Myelin Proteins', 'Point Mutation', 'Sural Nerve'] | 23,781,966 | [['M01.060.116'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['D12.776.543.620', 'D12.776.631.580'], ['G05.365.590.675'], ['A08.800.800.720.450.760.8... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An exploratory analysis of associations of diet, sun exposure, and body composition with 25OHD at five years of age: Findings from the ROLO Kids Study. | Serum 25-hydroxyvitamin D (25OHD) is the main circulating form of vitamin D in the blood. Vitamin D status in adults is determined by numerous factors such as oral intake, skin generation, and body composition. However, there is limited understanding regarding determinants of 25OHD in young children. The aim of this st... | ['Body Composition', 'Child, Preschool', 'Diet', 'Feeding Behavior', 'Female', 'Humans', 'Life Style', 'Male', 'Nutritional Status', 'Sunlight', 'Sunscreening Agents', 'Vitamin D', 'Vitamin D Deficiency'] | 30,605,775 | [['G02.111.130', 'G03.180', 'G07.100.049'], ['M01.060.406.448'], ['G07.203.650.240'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['G07.203.650.650', 'N01.224.425.525'], ['G01.358.500.505.650.836', 'G01.750.250.650.836', 'G01.750.770.578.836',... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Contrast-enhanced ultrasound detects gallbladder perforation in a patient with acute abdominal pain. | We present the case of a patient with abdominal pain, in which gallbladder perforation was detected by contrast-enhanced ultrasound. A 90-year-old patient presented to the emergency department with a complaint of acute abdominal pain and vomiting. An abdominal ultrasound revealed a thickened gallbladder wall and small ... | ['Abdomen, Acute', 'Aged, 80 and over', 'Cholecystitis', 'Contrast Media', 'Gallbladder Diseases', 'Humans', 'Male', 'Phospholipids', 'Rupture, Spontaneous', 'Sulfur Hexafluoride', 'Ultrasonography'] | 21,447,432 | [['C23.888.592.612.054.200', 'C23.888.821.030.249'], ['M01.060.116.100.080'], ['C06.130.564.263'], ['D27.505.259.500', 'D27.720.259'], ['C06.130.564'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.570.755'], ['C23.300.909'], ['D01.303.350.300.900', 'D01.362.820', 'D01.875.812'], ['E01.370.350.850']] | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A case of a patient with protein C deficiency presenting with concurrent thromboses in the pulmonary arteries and innominate artery: a suggestive computed tomographic finding of thrombophilia. | The incidence of arterial thrombosis in patients with protein C deficiency is relatively low compared with that of venous thrombosis. To our knowledge, there is no previously published report of a protein C deficiency patient with simultaneous thromboses in the pulmonary artery and innominate artery in the English lite... | ['Adult', 'Brachiocephalic Trunk', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Humans', 'Protein C Deficiency', 'Pulmonary Artery', 'Risk Factors', 'Thrombophilia', 'Thrombosis', 'Tomography, X-Ray Computed', 'Warfarin'] | 22,487,990 | [['M01.060.116'], ['A07.015.114.145'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.378.100.100.690', 'C15.378.147.880', 'C15.378.925.795', 'C16.320.099.690'], ['A07.015.114.715'], ['E05.318.740.600.800.725... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Robotic thoracic surgery: an evolution in progress for the treatment of lung cancer. | The field of robotic thoracic surgery has exploded in the last five years. Robotic technology allows the surgeon to perform complex operations with smaller incisions. As robotic systems become smaller, more efficient and the surgeons gain more experience, the results will continue to improve. The goal is less trauma to... | ['Humans', 'Lung Neoplasms', 'Pneumonectomy', 'Robotics', 'Thoracic Surgery, Video-Assisted'] | 22,953,595 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E04.620', 'E04.928.600.600'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['E01.370.388.250.840.830', 'E01.370.388.250.950.830', 'E04.502.250.840.830', 'E04.502.250.950.830', 'E04.928.752.830']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Targeted elimination of activated hepatic stellate cells by an anti-epidermal growth factor-receptor single chain fragment variable antibody-tumor necrosis factor-related apoptosis-inducing ligand (scFv425-sTRAIL). | BACKGROUND: Progressive liver fibrosis is the result of chronic liver injury and is characterized by the excessive accumulation of extracellular matrix that may result in liver failure. Activated hepatic stellate cells are known to play a central role in this process and their elimination is a crucial step towards the ... | ['Actins', 'Apoptosis', 'Caspase 3', 'Caspase 7', 'Cell Line', 'Cell Proliferation', 'Cell Survival', 'Collagen Type I', 'ErbB Receptors', 'Hepatic Stellate Cells', 'Humans', 'Immunohistochemistry', 'Single-Chain Antibodies', 'TNF-Related Apoptosis-Inducing Ligand'] | 25,088,657 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126.350.700', 'D08.811.277.656.300.200.126.350.700', 'D12.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
FGF8 and FGFR3 are up-regulated in hypertrophic chondrocytes: Association with chondrocyte death in deep zone of Kashin-Beck disease. | OBJECTIVE: The aim of this study was to investigate FGF8 and FGFR3 expression in clinical samples of Kashin-Beck disease (KBD), an endemic osteochondropathy found in China, as well as in pre-clinical models of this disease.METHOD: Cartilage was collected from the hand phalanges of five patients with KBD and from five h... | ['Animals', 'Biomarkers', 'Cartilage, Articular', 'Cell Death', 'Cell Differentiation', 'Cell Line', 'Child', 'Child, Preschool', 'Chondrocytes', 'Disease Models, Animal', 'Fibroblast Growth Factor 8', 'Humans', 'Hypertrophy', 'Kashin-Beck Disease', 'Male', 'Molsidomine', 'Rats, Sprague-Dawley', 'Receptor, Fibroblast G... | 29,626,475 | [['B01.050'], ['D23.101'], ['A02.165.407.150', 'A02.835.583.192'], ['G04.146'], ['G04.152'], ['A11.251.210'], ['M01.060.406'], ['M01.060.406.448'], ['A11.329.171'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.624.180', 'D12.776.467.624.180', 'D23.529.624.180'], ['B01.050.150.900.649.313.988.400.112.400... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Increased autoantibody production by NZB/NZW B cells in response to IL-5. | We previously demonstrated that B cells from NZB/NZW but not nonautoimmune mice secrete high levels of autoantibodies in response to factor(s) derived from type 2 Th cell (Th2) clones. Supernatants from type 1 Th cell clones, which contain a different set of lymphokines, were not stimulatory. In the present experiments... | ['Animals', 'Antibodies, Antinuclear', 'Autoantibodies', 'B-Lymphocytes', 'Cell-Free System', 'Dose-Response Relationship, Immunologic', 'Female', 'Interleukin-4', 'Interleukin-5', 'Interleukins', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred NZB', 'T-Lymphocytes, Helper-Inducer'] | 2,969,393 | [['B01.050'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.49... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conserved interaction of Ctf18-RFC with DNA polymerase å is critical for maintenance of genome stability in Saccharomyces cerevisiae. | Human Ctf18-RFC, a PCNA loader complex, interacts with DNA polymerase å (Polå) through a structure formed by the Ctf18, Dcc1 and Ctf8 subunits. The C-terminal stretch of Ctf18, which is highly conserved from yeast to human, is necessary to form the Polå-capturing structure. We found that in the budding yeast Saccharomy... | ['Animals', 'Chromosomal Proteins, Non-Histone', 'DNA Polymerase II', 'DNA Replication', 'DNA-Binding Proteins', 'Genomic Instability', 'HEK293 Cells', 'Humans', 'Mice', 'Proliferating Cell Nuclear Antigen', 'Replication Protein C', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 26,987,677 | [['B01.050'], ['D12.776.660.235', 'D12.776.664.235'], ['D08.811.913.696.445.308.300.230'], ['G02.111.225', 'G05.226'], ['D12.776.260'], ['C23.550.362', 'G05.365.590.335', 'G05.370'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acetazolamide in prevention of acute mountain sickness. | A controlled comparative between-group study of 48 climbers ascending Kilimanjaro (5895m) was designed as an extension to our previous double-blind cross-over trial on the same peak in 1980, using acetazolamide to decrease the incidence and effects of Acute Mountain Sickness. A group taking acetazolamide 500 mg each mo... | ['Acetazolamide', 'Acute Disease', 'Adult', 'Altitude Sickness', 'Clinical Trials as Topic', 'Double-Blind Method', 'Female', 'Humans', 'Hypoxia', 'Male', 'Middle Aged', 'Mountaineering'] | 3,533,677 | [['D02.886.675.867.060', 'D03.383.129.708.867.060'], ['C23.550.291.125'], ['M01.060.116'], ['C08.618.020'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Lipid bilayer with ion channels--a dipole with inductive properties]. | A cyclic peptide-alamethicin forms cation selective channels in lipid bilayers. Anomalous behavior of bilayer capacitance observed during impedance measurements of the planar bilayer containing the peptide is reported. The band of the frequencies used is 30-30000 Hz. The bilayer capacitance measured at a given frequenc... | ['Electric Conductivity', 'Lipid Bilayers', 'Membrane Potentials', 'Models, Biological', 'Phospholipids'] | 6,722,204 | [['G01.358.500.249.277'], ['D10.570.510', 'J01.637.087.500.510'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E05.599.395'], ['D10.570.755']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The invasive cestode parasite Ligula from salmonids and bullies on the South Island, New Zealand. | Freshwater ecosystems are often impacted by biological invasions, including the introduction of exotic parasites capable of infecting native species. Here, we report the occurrence of the introduced tapeworm Ligula sp. from common bully, Gobiomorphus cotidianus, and quinnat salmon, Oncorhynchus tshawytscha, in Lake Haw... | ['Animals', 'Cestoda', 'Cestode Infections', 'Ecosystem', 'Female', 'Fish Diseases', 'Fishes', 'Lakes', 'Male', 'New Zealand', 'Salmon'] | 29,177,582 | [['B01.050'], ['B01.050.500.500.736.215'], ['C01.610.335.190'], ['G16.500.275.157', 'N06.230.124'], ['C22.362'], ['B01.050.150.900.493'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['Z01.639.760.747', 'Z01.678.100.747'], ['B01.050.150.900.493.817.750.705']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Physiological effects of indomethacin and celecobix: an S-transform laser Doppler flowmetry signal analysis. | Conventional signal processing typically involves frequency selective techniques which are highly inadequate for nonstationary signals. In this paper, we present an approach to perform time-frequency selective processing of laser Doppler flowmetry (LDF) signals using the S-transform. The approach is motivated by the ex... | ['Administration, Oral', 'Adult', 'Algorithms', 'Anti-Inflammatory Agents', 'Blood Flow Velocity', 'Celecoxib', 'Diagnosis, Computer-Assisted', 'Female', 'Humans', 'Indomethacin', 'Laser-Doppler Flowmetry', 'Male', 'Pyrazoles', 'Signal Processing, Computer-Assisted', 'Single-Blind Method', 'Skin', 'Sulfonamides', 'Trea... | 15,843,729 | [['E02.319.267.100'], ['M01.060.116'], ['G17.035', 'L01.224.050'], ['D27.505.954.158'], ['E01.370.370.130', 'G09.330.380.630.080'], ['D02.065.884.247', 'D02.886.590.700.247', 'D03.383.129.539.160'], ['E01.158', 'L01.313.500.750.100.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.420'], ['E01.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Sentence retrieval for abstracts of randomized controlled trials. | BACKGROUND: The practice of evidence-based medicine (EBM) requires clinicians to integrate their expertise with the latest scientific research. But this is becoming increasingly difficult with the growing numbers of published articles. There is a clear need for better tools to improve clinician's ability to search the ... | ['Abstracting and Indexing', 'Humans', 'Information Storage and Retrieval', 'Natural Language Processing', 'Randomized Controlled Trials as Topic'] | 19,208,256 | [['L01.453.245.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280', 'L01.470'], ['L01.224.050.375.580'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500']] | ['Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Endometrial and subendometrial blood flow measured by three-dimensional power Doppler ultrasound in patients with small intramural uterine fibroids during IVF treatment. | BACKGROUND: The impact of intramural fibroids on the success of IVF treatment is controversial and the mechanisms leading to poor treatment outcomes remain unknown. We compared endometrial and subendometrial blood flow between women with and without intramural fibroids during IVF treatment.METHODS: Three-dimensional (3... | ['Adult', 'Endometrium', 'Female', 'Fertilization in Vitro', 'Humans', 'Infertility, Female', 'Leiomyoma', 'Regional Blood Flow', 'Ultrasonography, Doppler'] | 15,576,392 | [['M01.060.116'], ['A05.360.319.679.490'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['C04.557.450.590.450'], ['G09.330.100.780'], ['E01.370.350.850.850']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incorporation of lysozyme-rectorite composites into chitosan films for antibacterial properties enhancement. | The demand for designing antibacterial materials was quite substantial in packing and biomedical materials fields. Chitosan had a wide utilization to satisfy this demand. In this study, by incorporating lysozyme (LY) - rectorite (REC) into chitosan films, the ultimately obtained hybrid films can own the enhanced antiba... | ['Aluminum Silicates', 'Anti-Bacterial Agents', 'Chitosan', 'Escherichia coli', 'Mechanical Phenomena', 'Minerals', 'Muramidase', 'Staphylococcus aureus', 'Structure-Activity Relationship', 'Temperature', 'Water'] | 28,450,247 | [['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['D27.505.954.122.085'], ['D05.750.078.139.500', 'D09.698.211.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.374'], ['D01.578'], ['D08.811.277.450.642'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Mitotic recombination in stable and unstable chromosome III disomics of Aspergillus nidulans. | Approximately 2% of the haploid breakdown sectors of heterozygous chromosome III disomics of Aspergillus nidulans are the result of recombination between the homologous chromosomes. The exchanges are concentrated between the two mutations spanning the centromere. Comparisons are made between disomics hemizygous for the... | ['Aspergillus nidulans', 'Centromere', 'Chromosome Mapping', 'Heterozygote', 'Mitosis', 'Recombination, Genetic'] | 3,327,614 | [['B01.300.381.081.420'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['E05.393.183'], ['G05.380.383'], ['G04.144.220.220.781', 'G05.113.220.781'], ['G05.728']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 trans-signaling in a murine model. | INTRODUCTION: Tumor cell interactions with the microenvironment, especially those of bone-marrow-derived myeloid cells, are important in various aspects of tumor metastasis. Myeloid-derived suppressor cells (MDSCs) have been suggested to constitute tumor-favoring microenvironments. In this study, we elucidated a novel ... | ['Animals', 'Breast Neoplasms', 'Cell Line, Tumor', 'Disease Models, Animal', 'Female', 'Interleukin-6', 'Interleukin-6 Receptor alpha Subunit', 'Mice', 'Myeloid Cells', 'Neoplasm Metastasis', 'Phosphorylation', 'STAT3 Transcription Factor', 'Signal Transduction', 'Tumor Burden', 'Tumor Microenvironment'] | 24,021,059 | [['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['D12.776.543.750.705.852.420.400.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.627'], ['C04... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analgesic, anti-inflammatory and anticancer activities of Combretin A and Combretin B isolated from Combretum fragrans F. HOFFM (Combretaceae) leaves. | Previous pharmacological and phytochemical studies showed that, Combretum fragrans F. HOFFM (Combretaceae) is a Cameroonian medicinal plant possessing numerous therapeutic virtues and rich in various active secondary metabolites. In this study, we investigate in vivo anti-nociceptive and anti-inflammatory activity and,... | ['Analgesics', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Antineoplastic Agents, Phytogenic', 'Combretum', 'Female', 'Humans', 'Inflammation', 'Male', 'Mice', 'Nitric Oxide', 'Plant Extracts', 'Plant Leaves', 'Rats', 'Rats, Wistar', 'Reactive Oxygen Species', 'Triterpenes', 'Tumor Necrosis Factor-alpha'] | 29,159,717 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.505.954.248.179'], ['B01.650.940.800.575.912.250.228.166'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['B01.050.150.900.649.313.992.635.505.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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