Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Double-stranded RNA elements associated with the MVX disease of Agaricus bisporus. | Double-stranded RNA (dsRNA) has been isolated from Agaricus bisporus fruit bodies exhibiting a wide range of disease symptoms. The symptoms which occurred singularly or in combination included; bare cropping areas on commercial beds (primordia disruption), crop delay, premature veil opening, off- or brown-coloured mush... | ['Agaricus', 'Agriculture', 'Electrophoresis, Agar Gel', 'Plant Diseases', 'Plant Viruses', 'RNA Viruses', 'RNA, Double-Stranded', 'RNA, Viral'] | 12,747,325 | [['B01.300.179.100.105'], ['J01.040'], ['E05.196.401.153', 'E05.301.300.100'], ['G15.610'], ['B04.715'], ['B04.820'], ['D13.444.735.490', 'G02.111.570.820.486.775', 'G05.360.580.775'], ['D13.444.735.828']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Scattered-light intensity fluctuations in diastolic rat cardiac muscle caused by spontaneous Ca++-dependent cellular mechanical oscillations. | Laser light scattered by nonstimulated rat cardiac muscle bathed in physiological saline containing a [Ca++] of 0.4-2.5 mM displays scattered-light intensity fluctuations (SLIF); the frequencies of both SLIF and resting force are Ca++ dependent. Direct inspection of these muscles by phase-contrast microscopy under inco... | ['Animals', 'Calcium', 'Diastole', 'Heart', 'In Vitro Techniques', 'Microscopy', 'Models, Biological', 'Rats', 'Rats, Inbred Strains', 'Scattering, Radiation'] | 6,886,671 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['A07.541'], ['E05.481'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['E05.599.395'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Transesophageal color Doppler echocardiography during mechanical assist circulation. | Information available to determine the optimal timing for separation of patients (pts) from mechanical assist circulation (MAC) is usually limited, due to the difficulty of transfer of patients with heavy MAC systems. To evaluate the clinical efficacy of transesophageal color Doppler echocardiography (TEE) in managemen... | ['Adult', 'Aged', 'Assisted Circulation', 'Coronary Circulation', 'Echocardiography, Doppler', 'Esophagus', 'Female', 'Heart Diseases', 'Heart Failure', 'Heart-Assist Devices', 'Humans', 'Intra-Aortic Balloon Pumping', 'Male', 'Middle Aged', 'Myocardial Contraction', 'Postoperative Complications'] | 2,597,574 | [['M01.060.116'], ['M01.060.116.100'], ['E04.050'], ['G09.330.100.324'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['A03.556.875.500'], ['C14.280'], ['C14.280.434'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Low Vitamin B(12) level as a risk factor for very early recurrent abortion. | OBJECTIVE: To examine the relationship between Vitamin B(12) deficiency and early recurrent abortion (ERA) or very early recurrent abortion (VERA) abortion around 5 weeks of amenorrhea.STUDY DESIGN: Serum B(12), folate and homocysteine levels were carried out in 110 consecutive women with unexplained ERA or VERA and in... | ['Abortion, Habitual', 'Adult', 'Dietary Supplements', 'Female', 'Gestational Age', 'Homocysteine', 'Humans', 'Pregnancy', 'Pregnancy Outcome', 'Risk Factors', 'Vitamin B 12', 'Vitamin B 12 Deficiency'] | 12,206,930 | [['C13.703.039.089'], ['M01.060.116'], ['G07.203.300.456', 'J02.500.456'], ['G07.345.500.325.235.968', 'G08.686.320'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', ... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Disruption of fungal cell wall by antifungal Echinacea extracts. | In addition to widespread use in reducing the symptoms of colds and flu, Echinacea is traditionally employed to treat fungal and bacterial infections. However, to date the mechanism of antimicrobial activity of Echinacea extracts remains unclear. We utilized a set of ∼4,600 viable gene deletion mutants of Saccha... | ['Antifungal Agents', 'Cell Wall', 'Cryptococcus neoformans', 'Drug Resistance, Fungal', 'Echinacea', 'Gene Deletion', 'Genes, Fungal', 'Microbial Sensitivity Tests', 'Plant Extracts', 'Point Mutation', 'Saccharomyces cerevisiae', 'Ultraviolet Rays'] | 20,429,770 | [['D27.505.954.122.136'], ['A11.284.183'], ['B01.300.381.258.366', 'B01.300.930.316.366'], ['G06.225.383', 'G07.690.773.984.269.383'], ['B01.650.940.800.575.912.250.100.310'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['E01.370.225... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Plasma 2-hydroxyglutarate, a promising prognostic biomarker candidate for skeletal muscle injury in Fischer 344 rats. | Previously, we have demonstrated the potential of plasma 2-hydroxyglutarate (2HG) as an easily detectable biomarker for skeletal muscle injury in rats. Here, we examined whether plasma 2HG was superior to conventional skeletal muscle damage biomarkers, including aspartate aminotransferase (AST), creatine kinase (CK), a... | ['Aniline Compounds', 'Animals', 'Biomarkers', 'Disease Models, Animal', 'Glutarates', 'Male', 'Muscle, Skeletal', 'Myofibrils', 'Necrosis', 'Pyridines', 'Quadriceps Muscle', 'Rats, Inbred F344', 'Time Factors', 'Vacuoles'] | 30,298,848 | [['D02.092.146'], ['B01.050'], ['D23.101'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.241.081.337.351'], ['A02.633.567', 'A10.690.552.500'], ['A10.690.552.875', 'A11.284.430.214.190.750.620', 'A11.620.249.850', 'A11.620.500.500'], ['C23.550.717'], ['D03.383.725'], ['A02.633.567.850'], ['B01.050.050.199.520.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Site-Selective Synthesis of (15)N- and (13)C-Enriched Flavin Mononucleotide Coenzyme Isotopologues. | Flavin mononucleotide (FMN) is a coenzyme for numerous proteins involved in key cellular and physiological processes. Isotopically labeled flavin is a powerful tool for studying the structure and mechanism of flavoenzyme-catalyzed reactions by a variety of techniques, including NMR, IR, Raman, and mass spectrometry. In... | ['Carbon Isotopes', 'Coenzymes', 'Flavin Mononucleotide', 'Isotope Labeling', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Nitrogen Isotopes', 'Spectrum Analysis, Raman'] | 27,176,708 | [['D01.268.150.075', 'D01.496.123'], ['D08.211'], ['D03.633.100.733.315.650.500', 'D03.633.300.507.650.500', 'D08.211.474.650.500', 'D13.695.827.349', 'D23.767.405.650.500'], ['E05.522'], ['E05.196.867.519'], ['E05.196.566'], ['D01.268.604.500', 'D01.362.625.500', 'D01.496.586'], ['E05.196.822.860', 'E05.196.867.890']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Research status, development and utilization of traditional Dai medicine in China]. | OBJECTIVE: To provide a reference for the development and utilization of Dai medicine by investigate the present situation and existing problems of traditional Dai medicine.METHOD: Combined with the previous relevant investigations and literature in the field, the key and the development direction of traditional Dai me... | ['China', 'Conservation of Natural Resources', 'Drugs, Chinese Herbal', 'History, 20th Century', 'History, Ancient', 'Medicine, Chinese Traditional', 'Plants, Medicinal'] | 25,993,781 | [['Z01.252.474.164'], ['J01.256', 'N06.230.080'], ['D20.215.784.500.350', 'D26.335'], ['K01.400.504.968'], ['K01.400.470'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['B01.650.560']] | ['Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Increasing the injection volume by dilution improves the onset of motor blockade, but not sensory blockade of ropivacaine for brachial plexus block. | BACKGROUND AND OBJECTIVE: Ropivacaine used for axillary plexus block provides effective motor and sensory blockade. Varying clinical dosage recommendations exist. Increasing the dosage by increasing the concentration showed no improvement in onset. We compared the behaviour of a constant dose of ropivacaine 150 mg dilu... | ['Amides', 'Anesthetics, Local', 'Brachial Plexus', 'Double-Blind Method', 'Electric Stimulation', 'Female', 'Hand', 'Humans', 'Male', 'Middle Aged', 'Motor Neurons', 'Muscle Contraction', 'Nerve Block', 'Neurons, Afferent', 'Prospective Studies', 'Ropivacaine', 'Sensation', 'Touch'] | 12,553,384 | [['D02.065'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['A08.800.800.720.050'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.723.402'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Application of a noninvasive oral fluid test for detection of treponemal IgG in a predominantly HIV-infected population. | The performance of a time-resolved fluorescence immunoassay (TRFIA) for detection of treponemal IgG from oral fluid specimens has been assessed in a predominantly HIV-infected population. Serological investigation is the method of choice for confirming clinical suspicion of syphilis; however, in the primary stage of di... | ['Adult', 'Antibodies, Bacterial', 'Female', 'Fluorescence', 'HIV Infections', 'Humans', 'Immunoassay', 'Immunoglobulin G', 'Male', 'Saliva', 'Sensitivity and Specificity', 'Syphilis', 'Treponema pallidum'] | 17,061,098 | [['M01.060.116'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Direct determination of saturable and non-saturable calcium uptake in the developing rat duodenum. | Significant changes in saturable and non-saturable intestinal calcium uptake processes occur during development of the rat. A modified 'free floating disc' assay was used to measure total, active and passive duodenal calcium uptake on matching duodenal segments from male Sprague Dawley rats aged 14 to 56 days of age. T... | ['Animals', 'Biological Transport', 'Biological Transport, Active', 'Calcium', 'Duodenum', 'In Vitro Techniques', 'Male', 'Rats', 'Rats, Sprague-Dawley'] | 8,558,828 | [['B01.050'], ['G03.143'], ['G03.143.310'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E05.481'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The effects of Peking Union Medical College Hospital Critical Ultrasonic Management scheme on the etiological diagnosis of dyspnea and/or hemodynamic instability in ICU patients]. | OBJECTIVE: To investigate the effects of Peking Union Medical College Hospital (PUMCH) Critical Ultrasonic Management (PCUM) scheme on the etiological diagnosis and treatment decisions for the patients with dyspnea and/or hemodynamic instability in ICU.METHODS: Patients who suffered from dyspnea and/or hemodynamic inst... | ['Dyspnea', 'Hemodynamics', 'Humans', 'Intensive Care Units', 'Physical Examination', 'Pulmonary Edema', 'Respiratory Distress Syndrome', 'Sensitivity and Specificity', 'Ultrasonics'] | 25,567,151 | [['C08.618.326', 'C23.888.852.371'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E01.370.600'], ['C08.381.742'], ['C08.381.840', 'C08.618.840'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.52... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients. | Increasing evidence supports the hypothesis that soluble misfolded protein assemblies contribute to the degeneration of postmitotic tissue in amyloid diseases. However, there is a dearth of reliable nonantibody-based probes for selectively detecting oligomeric aggregate structures circulating in plasma or deposited in ... | ['Amyloidosis, Familial', 'Benzoxazoles', 'Case-Control Studies', 'Cross-Linking Reagents', 'Diazomethane', 'Genotype', 'Humans', 'Ions', 'Light', 'Molecular Probes', 'Molecular Weight', 'Peptides', 'Prealbumin', 'Protein Folding', 'Protein Multimerization', 'Protein Structure, Secondary', 'Proteolysis', 'Proteomics', ... | 28,904,227 | [['C16.320.565.176', 'C18.452.648.176', 'C18.452.845.500.075'], ['D03.633.100.221'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D27.720.470.410.210'], ['D02.172.383.383'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497'], ['G01.358.500.505.650', 'G01.59... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhibition of cerebroside synthesis in the brains of mice treated with L-cycloserine. | Subcutaneous injection of L-cycloserine resulted in a 28% reduction in cerebroside levels in mouse brain but had no effect on the levels of gangliosides. In contrast, intraperitoneal injection results in a reduction of ganglioside as well as cerebroside + sulfatide levels. The route of injection influenced the degree o... | ['Animals', 'Brain', 'Cerebrosides', 'Cycloserine', 'Gangliosides', 'Glycolipids', 'Kinetics', 'Male', 'Mice', 'Oxo-Acid-Lyases', 'Tritium'] | 4,009,064 | [['B01.050'], ['A08.186.211'], ['D02.065.313.250', 'D09.400.410.420.525.200.250', 'D10.390.470.675.200.250', 'D10.570.877.360.612.200.250'], ['D03.383.129.385.162', 'D03.383.129.462.600.162', 'D12.125.154.800.750'], ['D09.400.410.420.025.475', 'D10.390.470.025.475', 'D10.570.877.360.025.475'], ['D09.400.410', 'D10.390'... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanism of paracetamol-induced hypotension in critically ill patients: a prospective observational cross-over study. | OBJECTIVE: To elucidate the mechanism of hypotension following intravenous administration of paracetamol (acetaminophen) to patients on the Intensive Care Unit.DESIGN: Prospective observational cross-over study.SETTING: Intensive Care Unit, University Hospital Kr?lovsk? Vinohrady, Prague, Czech Republic.METHODS: Ventil... | ['Acetaminophen', 'Aged', 'Antipyretics', 'Body Temperature', 'Critical Illness', 'Cross-Over Studies', 'Female', 'Hemodynamics', 'Humans', 'Hypotension', 'Infusions, Intravenous', 'Male', 'Middle Aged', 'Prospective Studies'] | 22,424,816 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['M01.060.116.100'], ['D27.505.696.068'], ['E01.370.600.875.374', 'G07.110'], ['C23.550.291.625'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.514'], ['E02.319.267.082.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rapid decompression of congenital hydrocephalus associated with parenchymal hemorrhage. | A newborn boy with congenital hydrocephalus was diagnosed with aqueductal stenosis using magnetic resonance imaging. Low-resistance ventriculoperitoneal shunt placement was followed by clinical deterioration. Repeat imaging studies revealed a collapsed cortical mantle with subdural hemorrhage. In addition to subdural b... | ['Brain', 'Cerebral Hemorrhage', 'Humans', 'Hydrocephalus', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Male', 'Ventriculoperitoneal Shunt'] | 7,579,757 | [['A08.186.211'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602'], ['M01.060.703.520'], ['E01.370.350.825.500'], ['E04.035.188.850', 'E04.525.170.850']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alternating hemiplegia of childhood: case report. | We report the case of a 3 1/2 year old girl who had had attacks of alternating hemiplegia from the age of 6 months. Peculiar features from the etiopathogenetic angle seem to be the presence of a ring of mild stenosis of the vertebral artery on the right side, the influence of the upright posture on the onset of the att... | ['Child, Preschool', 'Constriction, Pathologic', 'Female', 'Flunarizine', 'Hemiplegia', 'Humans', 'Posture', 'Radiography', 'Vertebral Artery'] | 1,624,283 | [['M01.060.406.448'], ['C23.300.287'], ['D03.383.606.450'], ['C10.597.622.295', 'C23.888.592.636.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.695'], ['E01.370.350.700'], ['A07.015.114.955']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adenosine A1 receptor potentiated glycinergic transmission in spinal cord dorsal horn of rats after peripheral inflammation. | Adenosine is present at the extracellular space within spinal cord dorsal horn and engaged in the processing of nociceptive sensory signals. Systemic or spinal administration of exogenous adenosine produces a potent analgesia against pathological pain. Here we found that inhibitory glycinergic neurotransmission was an ... | ['Adenosine', 'Animals', 'HEK293 Cells', 'Humans', 'Inflammation', 'Inhibitory Postsynaptic Potentials', 'Male', 'Rats, Sprague-Dawley', 'Receptor, Adenosine A1', 'Receptors, Glycine', 'Signal Transduction', 'Spinal Cord Dorsal Horn'] | 28,882,563 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['G04.580.887.374', 'G07.265.675.887.374', 'G07.265.755.500', 'G07.265.880.750.400', 'G11.561.570.918.374', 'G11.561.616.500', 'G11.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Arabidopsis H+-PPase AVP1 regulates auxin-mediated organ development. | The transport of auxin controls developmental events in plants. Here, we report that in addition to maintaining vacuolar pH, the H+-pyrophosphatase, AVP1, controls auxin transport and consequently auxin-dependent development. AVP1 overexpression results in increased cell division at the onset of organ formation, hyperp... | ['Adenosine Triphosphatases', 'Arabidopsis', 'Arabidopsis Proteins', 'Biological Transport', 'Cell Count', 'Cell Proliferation', 'Cell Shape', 'Cell Wall', 'Hydrogen-Ion Concentration', 'In Situ Hybridization', 'Indoleacetic Acids', 'Inorganic Pyrophosphatase', 'Membrane Transport Proteins', 'Meristem', 'Microsomes', '... | 16,210,544 | [['D08.811.277.040.025'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G03.143'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.320'], ['A11.284.183'], ['G02.300'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fibromatosis of the larynx in the adult. | We describe the fourth case of aggressive fibromatosis of the larynx arising in an adult. Most cases of laryngeal fibromatosis have been described in children. In the larynx it may behave the same as in other sites, with local aggressiveness but without metastasis. The possible differential diagnoses are discussed. | ['Aged', 'Diagnosis, Differential', 'Fibroma', 'Humans', 'Laryngeal Neoplasms', 'Male'] | 2,614,246 | [['M01.060.116.100'], ['E01.171'], ['C04.557.450.565.590.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fluorinated amphiphilic amino acid derivatives as antioxidant carriers: a new class of protective agents. | The use of classical antioxidants is limited by their low bioavailabilities, and therefore, high doses are usually required to display significant protective activity. In a recent article (J. Med. Chem. 2003, 46, 5230) we showed that the ability of the alpha-phenyl-N-tert-butylnitrone (PBN) to restore the viability of ... | ['Amino Acids', 'Animals', 'Antioxidants', 'Cell Death', 'Cells, Cultured', 'Chemical Phenomena', 'Chemistry, Physical', 'Doxorubicin', 'Fluorine', 'Hydrogen Peroxide', 'Molecular Structure', 'Oxidation-Reduction', 'Protective Agents', 'Surface-Active Agents'] | 16,640,342 | [['D12.125'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146'], ['A11.251'], ['G02'], ['H01.181.529'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D01.268.380.300'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.65... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk of clinically significant depression in HIV-infected patients: effect of antiretroviral drugs. | OBJECTIVES: We aimed to characterize depression in newly diagnosed HIV-infected patients, to determine the effect of antiretroviral therapy (ART) on its incidence, and to investigate whether efavirenz use was associated with a higher risk, compared with non-efavirenz-containing regimens, in the Spanish CoRIS cohort.MET... | ['Adult', 'Alkynes', 'Anti-HIV Agents', 'Benzoxazines', 'Cyclopropanes', 'Depression', 'Female', 'HIV Infections', 'Humans', 'Male', 'Middle Aged', 'Poisson Distribution', 'Prospective Studies', 'Reverse Transcriptase Inhibitors'] | 24,215,356 | [['M01.060.116'], ['D02.455.326.397'], ['D27.505.954.122.388.077.088'], ['D03.383.533.249', 'D03.633.100.209'], ['D02.455.426.392.368.533'], ['F01.145.126.350'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
GC-MS analysis of amino acid enantiomers as their N(O,S)-perfluoroacyl perfluoroalkyl esters: application to space analysis. | The target of the in-situ research of optical activity in extraterrestrial samples stimulated an extended investigation of a GC-MS method based on the derivatization of amino acids by using a mixture of perfluorinated alcohols and perfluorinated anhydrides. Amino acids are converted to their N(O,S)-perfluoroacyl perflu... | ['Acylation', 'Amino Acids', 'Calibration', 'Esterification', 'Esters', 'Gas Chromatography-Mass Spectrometry', 'Molecular Structure', 'Reference Standards', 'Space Flight', 'Stereoisomerism', 'Time Factors', 'Volatilization'] | 16,534,802 | [['G02.111.012', 'G02.607.063', 'G03.040'], ['D12.125'], ['E05.978.155'], ['G02.111.270', 'G02.607.250', 'G03.344'], ['D02.241.400'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G02.111.570', 'G02.466'], ['E05.978.808'], ['J01.937.285.850'], ['G02.607.445.682'], ['G01.910.857'], ['G01.645.750', 'G02.734.933']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Microbiological flora and nail polish: a brief report. | Removing nail polish and prosthetic nails from operating room (OR) personnel prior to scrubbing and from patients prior to hand surgery is recommended but not practiced in many hospitals. There is concern that nail polish can act as a vehicle for the transfer of infectious agents. This study was designed to determine t... | ['Acinetobacter', 'Bacteria', 'Cosmetics', 'Female', 'Hand', 'Hand Disinfection', 'Humans', 'Infection Control', 'Nails', 'Operating Rooms', 'Staphylococcus epidermidis'] | 7,815,184 | [['B03.440.400.425.537.050', 'B03.660.250.530.050'], ['B03'], ['D27.720.269', 'J01.516.213'], ['A01.378.800.667'], ['N06.850.670.150.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.780.200.450'], ['A17.600'], ['N02.278.388.700'], ['B03.300.390.400.800.750.343', 'B03.353.500.750.750.343', 'B03.510.100.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Non-consumptive predator effects shape honey bee foraging and recruitment dancing. | Predators can reduce bee pollination and plant fitness through successful predation and non-consumptive effects. In honey bees, evidence of predation or a direct attack can decrease recruitment dancing and thereby magnify the effects of individual predation attempts at a colony level. However, actual predation attempts... | ['Analysis of Variance', 'Animal Communication', 'Animals', 'Appetitive Behavior', 'Avoidance Learning', 'Bees', 'Body Size', 'California', 'Choice Behavior', 'Ecosystem', 'Flight, Animal', 'Mantodea', 'Predatory Behavior'] | 24,475,292 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.145.113.055'], ['B01.050'], ['F01.145.113.111'], ['F02.463.425.097', 'F02.463.785.373.173'], ['B01.050.500.131.617.720.500.500.875.387'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['Z01.107.567.875.580.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Efficacy and safety of repeated doses of botulinum toxin type B in type A resistant and responsive cervical dystonia. | Efficacy of botulinum toxin type B (BoNT B) for the treatment of type A-resistant (AR) and non-A-resistant (NAR) cervical dystonia (CD) has been demonstrated in several single injection studies. There is little data available on long-term therapy with repeated injection sessions and it is unknown if AR and NAR patients... | ['Botulinum Toxins, Type A', 'Electromyography', 'Female', 'Humans', 'Injections, Intramuscular', 'Male', 'Middle Aged', 'Neuromuscular Agents', 'Prospective Studies', 'Surveys and Questionnaires', 'Torticollis'] | 15,954,134 | [['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.460'], ['M01.060.116.630'], ['D27.505.696.663.700'], ['E05.318.372.500.750.625', 'N05.715.360.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expanded phenotype and ethnicity in Setleis syndrome. | Setleis syndrome, an autosomal recessive disorder characterized by "coarse" face, temporal cutis aplasia, double upper eyelashes, absent lower eyelashes, chronic conjunctivitis, and prominent thick lips, was reported previously in 8 Puerto Rican children. We report on 3 unrelated children (one mentally retarded) with S... | ['Abnormalities, Multiple', 'Chile', 'China', 'Europe', 'Eyelashes', 'Face', 'Female', 'Humans', 'Infant, Newborn', 'Male', 'Phenotype', 'Puerto Rico', 'Skin Abnormalities', 'Syndrome', 'United States'] | 2,596,524 | [['C16.131.077'], ['Z01.107.757.235'], ['Z01.252.474.164'], ['Z01.542'], ['A01.456.505.420.504.421', 'A09.371.337.338', 'A17.360.421'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G05.695'], ['Z01.107.084.900.750', 'Z01.639.880.750'], ['C16.131.831', 'C17.800.804'], ['C23.55... | ['Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Relation of mast cell, nerve and fibrosis in appendix. | The relationship of mast cells, nerves and fibrosis was studied in 50 cases of Appendix using simple histochemical technique. In the mucosa, the mast cell number was greater in the early stages of fibrosis. Both in the mucosa and submucosa mast cells were found closely associated with neural tissue. As the fibrosis inc... | ['Appendicitis', 'Appendix', 'Cell Count', 'Fibrosis', 'Humans', 'Hyperplasia', 'Intestinal Mucosa', 'Mast Cells', 'Neurons', 'Tolonium Chloride'] | 9,581,073 | [['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['A03.556.124.526.209.290', 'A03.556.249.249.209.290'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['C23.550.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['A03.556.124.369', 'A10.615.550.444'], ['A11.329.4... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Pros and cons of adding an accessory breathing system to the main circle circuit. II. Arguments against their use]. | When compared to the circle system alternative breathing systems (ABS) are of no benefit. When the only indication of an ABS is emergency oxygen administration it should be connected to the O2 pipeline upstream from the flowmeter bank and the vaporiser. The use of an ABS for anaesthesia maintenance is no longer justifi... | ['Anesthesia, Closed-Circuit', 'Carbon Dioxide', 'Humans', 'Monitoring, Intraoperative', 'Oxygen', 'Respiration', 'Respiration, Artificial'] | 9,750,769 | [['E03.155.197.197.280'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520.510', 'E04.510'], ['D01.268.185.550', 'D01.362.670'], ['G09.772.705'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of hyperventilation and hypoventilation on PaCO2 and intracranial pressure during acute elevations of intraabdominal pressure with CO2 pneumoperitoneum: large animal observations. | BACKGROUND: The side effects of acute elevations in intraabdominal pressure (IAP) are related to a multifactorial etiology. Previous studies have reported that acute elevations in IAP produce an immediate increase in intracranial pressure (ICP). This study was designed to analyze the reasons for increased ICP during ac... | ['Abdomen', 'Animals', 'Carbon Dioxide', 'Female', 'Hyperventilation', 'Hypoventilation', 'Intracranial Hypertension', 'Intracranial Pressure', 'Pneumoperitoneum, Artificial', 'Pressure', 'Swine'] | 9,660,022 | [['A01.923.047'], ['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['C08.618.501', 'C23.888.852.591'], ['C08.618.846.565', 'C23.888.852.638'], ['C10.228.140.631'], ['G11.561.170.505'], ['E01.370.388.605'], ['G01.374.715'], ['B01.050.150.900.649.313.500.880']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of genes involved in placental glucose uptake and transport in the nonobese diabetic mouse pregnancy. | OBJECTIVE: Maternal diabetes alters placental glucose metabolism and maternofetal glucose transport. The purpose of this study was to determine whether genes involved in placental glucose uptake and transport were concomitantly altered, resulting in the observed changes in the state of maternal diabetes.STUDY DESIGN: B... | ['Animals', 'Biological Transport', 'Diabetes Mellitus, Experimental', 'Female', 'Gene Expression', 'Glucose', 'Glycogen', 'Hexokinase', 'Mice', 'Mice, Inbred Strains', 'Monosaccharide Transport Proteins', 'Organ Size', 'Placenta', 'Pregnancy', 'Pregnancy in Diabetics', 'RNA, Messenger'] | 7,977,540 | [['B01.050'], ['G03.143'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['G05.297'], ['D09.947.875.359.448'], ['D05.750.078.562.388', 'D09.698.365.388'], ['D08.811.913.696.620.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SIRT1 suppresses the migration and invasion of gastric cancer by regulating ARHGAP5 expression. | Gastric cancer (GC) ranks among the top five malignant tumors worldwide by the incidence and mortality rate. However, the mechanisms underlying its progression are poorly understood. In this study, we investigated the role of SIRT1, a class III deacetylase, in the invasion and metastasis of GC. Here, we found that knoc... | ['Animals', 'Biomarkers, Tumor', 'Cell Line, Tumor', 'Cell Movement', 'Disease Progression', 'Down-Regulation', 'GTPase-Activating Proteins', 'Gene Expression Regulation, Neoplastic', 'Gene Knockdown Techniques', 'Gene Silencing', 'Genes, jun', 'Humans', 'Male', 'Mice', 'Mice, Nude', 'Multivariate Analysis', 'Neoplasm ... | 30,250,020 | [['B01.050'], ['D23.101.140'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['C23.550.291.656'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D12.644.360.325.150', 'D12.776.476.325.150'], ['G05.308.370'], ['E05.393.335.500'], ['G05.308.203.374'], ['G05.360.340.024.340.375.500.791.365'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Proton-beam therapy for hepatocellular carcinoma associated with portal vein tumor thrombosis. | BACKGROUND AND PURPOSE: The prognosis of patients with advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is extremely poor, as effective treatment options are limited. The authors performed a retrospective review to evaluate the efficacy of proton-beam therapy (PBT) for patients presentin... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Hepatocellular', 'Combined Modality Therapy', 'Disease Progression', 'Disease-Free Survival', 'Dose Fractionation, Radiation', 'Female', 'Follow-Up Studies', 'Humans', 'Liver Neoplasms', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Neoplast... | 20,013,087 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E02.186'], ['C23.550.291.656'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures in Human Peripheral Blood Mononuclear Cells. | BACKGROUND: Adjuvant System 03 (AS03) markedly enhances responses to influenza A/H5N1 vaccines, but the mechanisms of this enhancement are incompletely understood.METHODS: Using ribonucleic acid sequencing on peripheral blood mononuclear cells (PBMCs) from AS03-adjuvanted and unadjuvanted inactivated H5N1 vaccine recip... | ['Adaptive Immunity', 'Adjuvants, Immunologic', 'Adult', 'Double-Blind Method', 'Drug Combinations', 'Gene Expression Profiling', 'Humans', 'Immunity, Innate', 'Influenza A Virus, H5N1 Subtype', 'Influenza Vaccines', 'Influenza, Human', 'Leukocytes', 'Polysorbates', 'Signal Transduction', 'Squalene', 'Young Adult', 'al... | 30,566,602 | [['G12.450.050'], ['D27.505.696.477.067'], ['M01.060.116'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D26.310'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.564'], ['B04.820.480.968.405.400.500'], ['D20.215.894.899.302'], ['C01.748.310', 'C01... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Removal of Zn(II) from simulated wastewater using an algal biofilm. | An algal biofilm was employed as a novel kind of adsorbing material to remove Zn(II) from simulated wastewater. The algal biofilm system formed by Oedogonium sp. was operated in a dynamic mode for a period of 14 days with an initial Zn(II) concentration of 10 mg/L. The average effluent Zn(II) concentration was 0.247 mg... | ['Adsorption', 'Biofilms', 'Bioreactors', 'Chlorophyta', 'Microscopy, Electron, Scanning', 'Spectroscopy, Fourier Transform Infrared', 'Waste Disposal, Fluid', 'Waste Water', 'Water Pollutants, Chemical', 'Zinc'] | 25,353,944 | [['G01.030', 'G02.020'], ['A20.593', 'G06.120'], ['E07.115', 'J01.897.120.115'], ['B01.650.940.150'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.932', 'N06.850.460.710.865'], ['D27.888.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
M?bius syndrome. Electron microscopic study of the extraocular muscles. | The medial rectus, external rectus and inferior oblique muscles were examined by electron microscopy in M?bius syndrome. The electron microscopic findings of the medial rectus and inferior oblique were of degenerative and inflammatory nature, whereas the lateral rectus showed complete fibrosis. The fibrotic lateral rec... | ['Child', 'Facial Muscles', 'Female', 'Humans', 'Microscopy, Electron', 'Neuromuscular Diseases', 'Strabismus', 'Syndrome'] | 6,545,388 | [['M01.060.406'], ['A02.633.567.400', 'A14.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['C10.668'], ['C10.292.562.887', 'C11.590.810'], ['C23.550.288.500']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway. | Bacterial adhesion is an important initial step in biofilm formation, which may cause problems in medical, environmental, and industrial settings. In spite of obvious phenotypic differences between attached and planktonic cells, knowledge about the genetic basis for these differences and how adhesion-induced changes ar... | ['Bacterial Adhesion', 'Bacterial Outer Membrane Proteins', 'Bacterial Proteins', 'Cell Division', 'Escherichia coli', 'Escherichia coli Proteins', 'Gene Expression Regulation, Bacterial', 'Genes, Reporter', 'Lac Operon', 'Lipoproteins', 'Membrane Proteins', 'Signal Transduction', 'Time Factors', 'Transcription, Geneti... | 11,830,644 | [['G06.099.050'], ['D12.776.097.120', 'D12.776.543.100'], ['D12.776.097'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.308.300'], ['G05.360.340.024.340.435'], ['G05.360.340.024.686.545', 'G05.360.340.358.207... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of dietary soy isoflavones on the accessory sex organs of the Wistar rat. | We evaluated the effects of three rodent diets differing in soybean meal content on the response of the seminal vesicles, prostate and bulbocavernosus/levator ani (BC/LA) muscle to androgens and anti-androgenic compounds in the Hershberger assay. The diets tested were (1) L5, a semi-synthetic phytoestrogen-free diet, (... | ['Androgen Antagonists', 'Animals', 'Body Weight', 'Dietary Proteins', 'Dose-Response Relationship, Drug', 'Drug Antagonism', 'Eating', 'Food', 'Isoflavones', 'Male', 'Orchiectomy', 'Organ Size', 'Oxazoles', 'Prostate', 'Rats', 'Rats, Wistar', 'Seminal Vesicles', 'Soybean Proteins', 'Testicular Hormones', 'Testosterone... | 12,842,186 | [['D06.347.065', 'D27.505.696.399.450.065'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968.310'], ['G07.203.650.283', 'G10.261.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Eight novel germline MLH1 and MSH2 mutations in hereditary non-polyposis colorectal cancer families from Spain. | Germline mutations in the MLH1 and MSH2 genes, account for the majority of HNPCC families. We have screened such families from Spain by using DGGE analysis and subsequent direct sequencing techniques. In eight families we identified six novel MLH1 and two novel MSH2 mutations comprising one frame shift mutation (c.1420... | ['Adaptor Proteins, Signal Transducing', 'Carrier Proteins', 'Colorectal Neoplasms, Hereditary Nonpolyposis', 'DNA', 'DNA Mutational Analysis', 'DNA-Binding Proteins', 'Family Health', 'Female', 'Germ-Line Mutation', 'Humans', 'Male', 'MutL Protein Homolog 1', 'MutS Homolog 2 Protein', 'Neoplasm Proteins', 'Nuclear Pro... | 11,748,856 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.776.157'], ['C04.588.274.476.411.307.190', 'C04.700.250', 'C06.301.371.411.307.190', 'C06.405.249.411.307.190', 'C06.405.469.158.356.190', 'C06.405.469.491.307.190', 'C16.320.700.250', 'C18.452.284.255'], ['D13.444.308'], ['E05.393.760.700.300'], ['D12.7... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Echographic study of the vitreoretinal interface in giant retinal tears. | Vitreous and vitreoretinal interface changes were evaluated in giant retinal tears in order to plan surgical approach. Vitreal sineresis was evident in patients affected by primary giant retinal tears; in patients affected by retinal disinsertion the vitreous was adherent to the edge of the posterior flap, and in giant... | ['Adult', 'Aged', 'Humans', 'Middle Aged', 'Retina', 'Retinal Detachment', 'Retinal Perforations', 'Scleral Buckling', 'Ultrasonography', 'Video Recording', 'Vitrectomy', 'Vitreous Body'] | 9,730,763 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A09.371.729'], ['C11.768.648'], ['C11.768.740'], ['E04.540.890'], ['E01.370.350.850'], ['L01.280.960'], ['E04.540.960'], ['A09.371.714.500']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Illinois Dental Anesthesia and Sedation Survey for 2016. | A statewide decennial survey was sent to practicing dentists holding sedation or general anesthesia permits to identify office sedation/general anesthesia trends and practices over the last 10 years. This survey constitutes the third such survey, spanning a total of 20 years. Of the 234 respondents in the 2016 survey, ... | ['Anesthesia, Dental', 'Anesthesia, General', 'Child', 'Conscious Sedation', 'Humans', 'Illinois', 'Surveys and Questionnaires'] | 31,184,940 | [['E03.155.141', 'E06.045'], ['E03.155.197'], ['M01.060.406'], ['E03.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.350', 'Z01.107.567.875.510.350'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Biological verification of heavy ion treatment planning. | Chinese hamster ovary (CHO) cells and thermoluminescent detectors (TLD-700) were used for physical and biological verification of heavy ion treatment planning. Experiments were performed in a cylindrical water phantom, in some cases with lung and bone equivalent material in front of the target volume. The results confi... | ['Animals', 'Bone and Bones', 'CHO Cells', 'Cell Survival', 'Cricetinae', 'Humans', 'Ions', 'Luminescent Measurements', 'Phantoms, Imaging', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Reproducibility of Results', 'Thermoluminescent Dosimetry'] | 9,615,343 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['A11.251.210.200', 'A11.436.155'], ['G04.346'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497'], ['E05.196.712.516'], ['E07.671'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['E05.318.3... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Updated cardiac concerns with rituximab use: A growing challenge. | A 62-year-old male was undergoing treatment of NHL with bone marrow involvement with thrombocytopenia. After 15min of starting of IV infusion of rituximab, he started having severe retrosternal chest pain, diagnosed as acute ST elevation inferior wall MI. Patient was pre-loaded with dual anti platelets. Coronary angiog... | ['Coronary Angiography', 'Dose-Response Relationship, Drug', 'Electrocardiography', 'Follow-Up Studies', 'Humans', 'Immunologic Factors', 'Infusions, Intravenous', 'Male', 'Middle Aged', 'Myocardial Revascularization', 'Rituximab', 'ST Elevation Myocardial Infarction'] | 27,751,304 | [['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nataniel, NAFTA, and Public Health at the U.S.-Mexico Border. | Advocating overall improvements in health for individuals and communities is a daunting but important task for nurses in particular, and for health care professionals in general. This is particularly true when focusing on the population along the 2,000-mile U.S.-Mexico border, a unique region in which distinct cultures... | ['Anecdotes as Topic', 'Commerce', 'Humans', 'International Cooperation', 'Male', 'Mexico', 'Policy Making', 'Public Health', 'United States', 'Young Adult'] | 19,903,276 | [['K01.517.067'], ['J01.219'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500'], ['Z01.107.567.589'], ['N03.706.742'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['Z01.107.567.875'], ['M01.060.116.815']] | ['Humanities [K]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Unusual structural properties of water within the hydration shell of hyperactive antifreeze protein. | Many hypotheses can be encountered explaining the mechanism of action of antifreeze proteins. One widespread theory postulates that the similarity of structural properties of solvation water of antifreeze proteins to ice is crucial to the antifreeze activity of these agents. In order to investigate this problem, the st... | ['Antifreeze Proteins', 'Computer Simulation', 'Hydrogen Bonding', 'Hydrophobic and Hydrophilic Interactions', 'Materials Testing', 'Models, Chemical', 'Molecular Conformation', 'Molecular Dynamics Simulation', 'Protein Conformation', 'Water'] | 25,106,616 | [['D12.776.053'], ['L01.224.160'], ['G02.282'], ['G02.409'], ['E05.570'], ['E05.599.495'], ['G02.111.570.820'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570.820.709'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pigment-epithelium-derived factor is upregulated in photocoagulated human retinal pigment epithelial cells. | There is much evidence that pigment-epithelium-derived factor (PEDF) is a potent antiangiogenic cytokine which inhibits retinal and choroidal neovascularization by inducing apoptosis in activated vascular endothelial cells. Furthermore, the regulation of PEDF appears to be linked to the regulation of vascular endotheli... | ['Blotting, Western', 'Cells, Cultured', 'Eye Proteins', 'Humans', 'Laser Coagulation', 'Nerve Growth Factors', 'Pigment Epithelium of Eye', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Serpins', 'Up-Regulation'] | 16,158,012 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['D12.776.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.520.745.410', 'E02.594.530', 'E04.014.520.530', 'E04.350.750.410', 'E04.540.630.410'], ['D12.644.276.860', 'D12.776.467.860', 'D12.77... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative study of high tibial osteotomy using dynamic axial fixator and locked low-profile plate in medial osteoarthritis of knee. | PURPOSE: The purpose of this study was to evaluate the role of medial opening wedge high tibial osteotomy (HTO) in medial unicompartmental osteoarthritis (MCOA) of knee and to compare between the two methods of osteotomy using either dynamic axial fixator (DAF) or locking compression plate (LCP).METHODS: A total of 20 ... | ['Bone Plates', 'External Fixators', 'Female', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Osteotomy', 'Postoperative Care', 'Preoperative Care', 'Prospective Studies', 'Range of Motion, Articular', 'Tibia'] | 25,528,742 | [['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.550.114.606.500', 'C05.799.613.500'], ['E04.555.580'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['E02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel immunoadsorption device for removing beta2-microglobulin from whole blood. | BACKGROUND: High plasma levels of beta2-microglobulin (beta2m) have been implicated in the formation of the severely destructive and potentially fatal amyloid deposits that are characteristic of dialysis-related amyloidosis (DRA). Conventional renal replacement technologies remove insufficient quantities of beta2m to n... | ['Blood Component Removal', 'Equipment Design', 'Humans', 'Immunosorbent Techniques', 'Kinetics', 'Plasmapheresis', 'Recombinant Proteins', 'beta 2-Microglobulin'] | 11,260,419 | [['E02.120'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.380', 'E05.601.470.380'], ['G01.374.661', 'G02.111.490'], ['E02.120.770', 'E02.912.715', 'E04.292.869'], ['D12.776.828'], ['D12.776.124.790.223.100', 'D12.776.377.715.182.100', 'D12.776.395.550.489.100', 'D12.776.543.550.439.100',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recurrent Neural Network Model for Constructive Peptide Design. | We present a generative long short-term memory (LSTM) recurrent neural network (RNN) for combinatorial de novo peptide design. RNN models capture patterns in sequential data and generate new data instances from the learned context. Amino acid sequences represent a suitable input for these machine-learning models. Gener... | ['Amino Acid Sequence', 'Anti-Infective Agents', 'Machine Learning', 'Models, Chemical', 'Neural Networks, Computer', 'Peptides'] | 29,355,319 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D27.505.954.122'], ['G17.035.250.500', 'L01.224.050.375.530'], ['E05.599.495'], ['G17.485', 'L01.224.050.375.605'], ['D12.644']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Particle size distribution predicts particulate phosphorus removal. | Particulate phosphorus (PP) is often the largest component of the total phosphorus (P) load in stormwater. Fine-resolution measurement of particle sizes allows us to investigate the mechanisms behind the removal of PP in stormwater wetlands, since the diameter of particles influences the settling velocity and the amoun... | ['Agriculture', 'Particle Size', 'Phosphorus', 'Water Pollutants, Chemical', 'Wetlands'] | 29,164,536 | [['J01.040'], ['G02.712'], ['D01.268.666'], ['D27.888.284.903.655'], ['G16.500.275.157.812', 'N06.230.124.625']] | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Aspergillus endocarditis: cure without surgical valve replacement. | We have reported a case of fungal native valve endocarditis due to Aspergillus sp in which cure was effected by medical therapy alone. An infected sternectomy wound from a previous aortic valve replacement was considered a contraindication to surgery. | ['Aged', 'Amphotericin B', 'Aspergillosis', 'Endocarditis', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Mitral Valve'] | 2,315,788 | [['M01.060.116.100'], ['D02.540.576.500.500'], ['C01.150.703.080'], ['C14.280.282'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.510.507']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessing DSM-5 section III personality traits and disorders with the MMPI-2-RF. | An alternative model for diagnosing personality disorders (PDs) appears in DSM-5 Section III. This model includes a set of dimensional personality traits, which along with impairment in personality functioning can be configured to represent one of six PDs. Although specific assessment instruments for these personality ... | ['Adolescent', 'Character', 'Diagnostic and Statistical Manual of Mental Disorders', 'Female', 'Humans', 'MMPI', 'Male', 'Personality Assessment', 'Personality Disorders', 'Psychometrics', 'Reproducibility of Results', 'Young Adult'] | 24,220,212 | [['M01.060.057'], ['F01.752.190'], ['L01.453.245.945.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.647.513.607'], ['F04.513'], ['F03.675'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Lineage-specific engraftment and outcomes after T-cell-depleted peripheral blood stem cell transplant with Flu/Cy/TBI conditioning. | Sixty patients with haematological malignancies received a myeloablative regimen of total body irradiation, cyclophosphamide and fludarabine followed by a T-cell-depleted peripheral blood stem cell transplant from a human leucocyte antigen identical sibling. To improve donor immune function, 1 x 10(7) CD3+ cells/kg wer... | ['Adolescent', 'Adult', 'Child', 'Cyclophosphamide', 'Female', 'Follow-Up Studies', 'Graft vs Host Disease', 'Hematologic Neoplasms', 'Humans', 'Immunosuppressive Agents', 'Lymphocyte Depletion', 'Lymphocyte Transfusion', 'Male', 'Peripheral Blood Stem Cell Transplantation', 'Proportional Hazards Models', 'Survival Rat... | 16,115,130 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C20.452'], ['C04.588.448', 'C15.378.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Low-iron conditions induces the hypersensitive reaction and pathogenicity hrp genes expression in Xanthomonas and is involved in modulation of hypersensitive response and virulence. | Expression of hrp (hypersensitive reaction and pathogenicity) genes inside the host is crucial for virulence of phytopathogenic bacteria. The hrp genes encode components of type3 secretion system (T3SS), HR elicitors and several regulators, which are involved in the co-ordinated expression of hrp genes in the host envi... | ['Bacterial Proteins', 'Gene Deletion', 'Gene Expression Regulation, Bacterial', 'Iron', 'Plant Diseases', 'Plant Leaves', 'Promoter Regions, Genetic', 'Virulence', 'Xanthomonas'] | 29,687,657 | [['D12.776.097'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.308.300'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G15.610'], ['A18.024.812'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G06.930'], ['B03.440.400.425.967.930', 'B03.660.250.915.930']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Study on hemostatic activities of the rhizome of Paris bashanensis. | UNLABELLED: CONTEXT. Paris bashanensis Wang et Tang (Liliaceae) is widely used in traditional Chinese medicine for the treatment of injuries, fractures and hemorrhage in Hubei and Sichuan Province.OBJECTIVE: The n-BuOH extract of Paris bashanensis was investigated for hemostatic activity and chemical constituents in or... | ['Animals', 'Bleeding Time', 'Butanols', 'Chromatography, High Pressure Liquid', 'Dose-Response Relationship, Drug', 'Hemostasis', 'Hemostatics', 'Liliaceae', 'Mice', 'Plant Extracts', 'Rhizome', 'Saponins', 'Solvents', 'Spectrophotometry, Ultraviolet', 'Time Factors', 'Whole Blood Coagulation Time'] | 23,855,262 | [['B01.050'], ['E01.370.225.625.625.100', 'E05.200.625.625.100', 'G09.188.087'], ['D02.033.415.110', 'D10.289.110'], ['E05.196.181.400.300'], ['G07.690.773.875', 'G07.690.936.500'], ['G09.188.390'], ['D27.505.954.502.270.463'], ['B01.650.940.800.575.912.250.618.875.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Quercetin attenuates Staphylococcus aureus virulence by reducing alpha-toxin secretion]. | Alpha toxin, a pore-forming protein with cytotoxic activity, is one of the major virulence factors secreted by most strains of Staphylococcus aureus. The relevance of this protein in the pathogenesis of pneumonia associated with S.aureus infections has already been established. Therefore, inhibiting alpha toxin secreti... | ['Antioxidants', 'Bacterial Toxins', 'Hemolysin Proteins', 'Humans', 'Quercetin', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Virulence', 'Virulence Factors'] | 29,100,712 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D23.946.123'], ['D12.776.543.695.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.663.283.266.450.284.777', 'D03.633.100.150.266.450.284.777'], ['C01.150.252.410.868'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Obesity/hyperleptinemic phenotype impairs structural and functional plasticity in the rat hippocampus. | Epidemiological studies estimate that greater than 60% of the adult US population may be categorized as either overweight or obese, and there is a growing appreciation that the complications of obesity extend to the central nervous system (CNS). While the vast majority of these studies have focused on the hypothalamus,... | ['Animals', 'Conditioning, Classical', 'Electroshock', 'Freezing Reaction, Cataleptic', 'Hippocampus', 'Leptin', 'Male', 'Neuronal Plasticity', 'Neurons', 'Obesity', 'Proto-Oncogene Proteins c-fos', 'Rats', 'Rats, Sprague-Dawley'] | 21,354,191 | [['B01.050'], ['F02.463.425.179.308'], ['E05.723.402.403', 'F04.669.224'], ['F01.145.113.555', 'F01.145.632.555', 'G11.427.410.698.555'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.500', 'D12.776.467.024.500', 'D23.529.024.500'], ['G11.561... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PINK1 stimulates interleukin-1â-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1. | Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. The cause of neuronal death in PD is largely unknown, but several genetic loci, including PTEN-induced putative kinase 1 (PINK1), have been linked to early onset autosomal recessive forms of familial PD. PIN... | ['Animals', 'Cells, Cultured', 'Humans', 'Inflammation', 'Interleukin-1beta', 'Interleukin-8', 'MAP Kinase Kinase Kinases', 'Mice', 'NF-kappa B', 'Phosphorylation', 'Protein Kinases', 'Protein Multimerization', 'Signal Transduction', 'TNF Receptor-Associated Factor 6', 'Ubiquitination'] | 22,643,835 | [['B01.050'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.776.467.374.500.400.600', 'D23.529.374.465.131.600', 'D23.529.374.500.400.600'], ['D12.644.276.374.200.120.800', 'D12.644.276.37... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
New low osmolality water-soluble contrast compounds in selective arteriography of the peripheral limbs. A comparative study. | Metrizamide (Amipaque) and ioxaglate (Hexabrix), both new low osmolality contrast agents, were evaluated in a comparative study of 50 patients with peripheral arterial diseases undergoing in total 118 angiograms. The degree of discomfort caused by the highly selective injection of these compounds and the normal availab... | ['Angiography', 'Contrast Media', 'Humans', 'Lidocaine', 'Meglumine', 'Metrizamide', 'Metrizoic Acid', 'Osmolar Concentration', 'Pain', 'Solubility', 'Tolazoline', 'Triiodobenzoic Acids', 'Water'] | 498,913 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlation of morphology, electrophysiology and chemistry of neurons in the myenteric plexus of the guinea-pig distal colon. | Intracellular recordings were made from myenteric neurons of the guinea-pig distal colon to determine their electrical behaviour in response to intracellular current injection and stimulation of synaptic inputs. The recording microelectrode contained the intracellular marker biocytin, which was injected into impaled ne... | ['Afferent Pathways', 'Animals', 'Colon', 'Electrophysiology', 'Excitatory Postsynaptic Potentials', 'Guinea Pigs', 'Interneurons', 'Myenteric Plexus', 'Neurons'] | 10,323,306 | [['A08.612.220'], ['B01.050'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['H01.158.344.528', 'H01.158.782.236'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['B01.050.150.900.649.313.992.550'], ['A08.675.358', 'A11.671.358'], ['A08.800.050.050.5... | ['Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Opsin spectral sensitivity determines the effectiveness of optogenetic termination of ventricular fibrillation in the human heart: a simulation study. | KEY POINTS: Optogenetics-based defibrillation, a theoretical alternative to electrotherapy, involves expression of light-sensitive ion channels in the heart (via gene or cell therapy) and illumination of the cardiac surfaces (via implanted LED arrays) to elicit light-induced activations. We used a biophysically detaile... | ['Channelrhodopsins', 'Computer Simulation', 'Heart', 'Humans', 'Light', 'Optogenetics', 'Patient-Specific Modeling', 'Ventricular Fibrillation'] | 26,941,055 | [['D12.776.157.530.400.163', 'D12.776.543.550.450.163', 'D12.776.543.585.400.163', 'D12.776.765.593.250'], ['L01.224.160'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.393.667'], ['E05.599.395.821', 'L01.224.160.750'],... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Proteomic profiling of birch (Betula verrucosa) pollen extracts from different origins. | Pollen of the European white birch is a major source of spring pollinosis in Europe. Pollen-allergy diagnosis and treatment by specific immunotherapy commonly rely on extracts of natural origin. To gain insight into the protein content and its variability, we evaluated the profile of allergenic and non-allergenic prote... | ['Allergens', 'Antigens, Plant', 'Betula', 'Immunoblotting', 'Mass Spectrometry', 'Plant Extracts', 'Plant Proteins', 'Pollen', 'Protein Isoforms', 'Proteomics'] | 21,360,672 | [['D23.050.063'], ['D23.050.291'], ['B01.650.940.800.575.912.250.859.750.200.750'], ['E05.478.566.320', 'E05.601.470.320'], ['E05.196.566'], ['D20.215.784.500', 'D26.667'], ['D12.776.765'], ['A18.024.249.500.249.500'], ['D12.776.800'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Reconstruction of the interosseous membrane of the forearm with a graft substitute: a cadaveric study. | PURPOSE: Longitudinal radioulnar dissociation occurs when traumatic axial loading through the wrist disrupts the interosseous membrane (IOM) of the forearm and fractures the radial head (Essex-Lopresti injury). Proximal migration of the radius results in a wrist with a positive ulnar variance, which leads ultimately to... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomechanical Phenomena', 'Cadaver', 'Elbow', 'Female', 'Forearm', 'Humans', 'Male', 'Membranes', 'Middle Aged', 'Movement', 'Radius', 'Radius Fractures', 'Tendons', 'Ulna', 'Weight-Bearing'] | 15,781,356 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G01.154.090', 'G01.374.089'], ['C23.550.260.224'], ['A01.378.800.420'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.615'], ['M01.060.116.630'], ['G07.568', 'G11.427.410'], ['A02.835.232.087.090.700'], ['C26.088.268.556', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
In situ high-volume modified continuous closed and/or open lavage for infected necrotizing pancreatitis. | OBJECTIVES: To evaluate the clinical significance of high-volume modified continuous closed and/or open lavage for the treatment of infected necrotizing pancreatitis.METHODS: From August 1997 to December 2006, 53 patients with infected necrotizing pancreatitis who underwent in situ high-volume (>20 L/d) continuous clos... | ['Biopsy, Fine-Needle', 'Debridement', 'Female', 'Humans', 'Infections', 'Male', 'Pancreatitis, Acute Necrotizing', 'Retrospective Studies', 'Therapeutic Irrigation'] | 18,192,880 | [['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E04.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['C06.689.750.650'], ['E05.318... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bacterial and fungal cometabolism of 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) and its breakdown products. | Resting cells of bacteria grown in the presence of diphenylmethane oxidized substituted analogs such as 4-hydroxydiphenylmethane, bis(4-hydroxyphenyl)methane, bis(4-chlorophenyl)methane (DDM), benzhydrol, and 4,4'-dichlorobenzhydrol. Resting cells of bacteria grown with benzhydrol as the sole carbon source oxidized sub... | ['Bacteria', 'DDT', 'Fungi'] | 3,994,362 | [['B03'], ['D02.455.526.439.255'], ['B01.300']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of non-penetrating glaucoma surgery on aqueous outflow facility in isolated porcine eyes. | PURPOSE: To investigate, in vitro, the influence of non-penetrating glaucoma surgery (NPGS) and the influence of tightly suturing the superficial scleral flap on the aqueous outflow facility of isolated porcine eyes.MATERIALS AND METHODS: The anterior chambers of 12 enucleated porcine cadaver eyes were cannulated and p... | ['Animals', 'Anterior Chamber', 'Aqueous Humor', 'Eye Enucleation', 'Glaucoma', 'Sclera', 'Surgical Flaps', 'Sutures', 'Swine'] | 15,205,245 | [['B01.050'], ['A09.371.060.067'], ['A09.371.060.067.070', 'A12.207.270.040'], ['E04.540.429'], ['C11.525.381'], ['A09.371.784'], ['A10.850.710', 'E07.862.710'], ['E07.858.690.820'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Different Phenotypes of the Two Chinese Probands with the Same c.889G>A (p.C162Y) Mutation in COCH Gene Verify Different Mechanisms Underlying Autosomal Dominant Nonsyndromic Deafness 9. | OBJECTIVES: By analyzing the different phenotypes of two Chinese DFNA9 families with the same mutation located in the intervening region between the LCCL and vWFA domains of cochlin and testing the functional changes in the mutant cochlin, we investigated the different pathogeneses for mutations in LCCL and vWFA domain... | ['Adult', 'Aged', 'Aged, 80 and over', 'Deafness', 'Electronystagmography', 'Extracellular Matrix Proteins', 'Female', 'Hearing Loss, Sensorineural', 'Humans', 'Male', 'Middle Aged', 'Mutation, Missense', 'Pedigree', 'Phenotype'] | 28,099,493 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['E01.370.380.230.280', 'E01.370.382.900.280', 'E01.370.405.245.787.280', 'E01.370.405.260'], ['D12.776.860.300'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.88... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Is forced oscillation technique useful in the diagnosis of occupational asthma? | OBJECTIVE: The aim of the study was to determine whether the forced oscillation technique (FOT), which does not require active cooperation, may be useful to assess bronchial responsiveness in patients with suspected occupational asthma (OA).METHODS: Changes in resistances evaluated by FOT, and DeltaFEV1 measured during... | ['Adolescent', 'Adult', 'Asthma', 'Bronchial Provocation Tests', 'Female', 'Forced Expiratory Volume', 'France', 'Humans', 'Male', 'Methacholine Chloride', 'Middle Aged', 'Occupational Diseases', 'ROC Curve', 'Smoking', 'Surveys and Questionnaires'] | 16,093,935 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E01.370.386.700.125'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.877.883.555.500', 'D02.675.276.534.500'], ['M01.060.116.630'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A new method of UV-patternable hydrophobization of micro- and nanofluidic networks. | This work reports a new method to hydrophobize glass-based micro- and nanofluidic networks. Conventional methods of hydrophobizing glass surfaces often create particulate debris causing clogging especially in shallow nanochannels or require skilful handling. Our novel method employs oxygen plasma, silicone oil and ultr... | ['Glass', 'Hydrophobic and Hydrophilic Interactions', 'Microfluidic Analytical Techniques', 'Nanotechnology', 'Oxygen', 'Silicone Oils', 'Surface Properties', 'Ultraviolet Rays', 'Water'] | 22,064,947 | [['J01.637.437'], ['G02.409'], ['E05.588.465'], ['H01.603', 'J01.897.520.600'], ['D01.268.185.550', 'D01.362.670'], ['D02.756.650.700.800', 'D05.750.900.850.950', 'D25.720.900.850.950', 'J01.637.051.720.900.850.950'], ['G02.860'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659', ... | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Genetic variation in the inhibin pathway and risk of testicular germ cell tumors. | Gene-knockout studies in mice suggest that INHA, encoding a subunit of gonadotropin-regulating proteins known as inhibins, is a tumor suppressor for testicular stromal cell tumors. It is not known whether genetic variation in the inhibin pathway also influences susceptibility to testicular germ cell tumors (TGCT), the ... | ['Animals', 'Case-Control Studies', 'Disease Models, Animal', 'Genetic Variation', 'Genotype', 'Humans', 'Inhibins', 'Male', 'Mice', 'Military Personnel', 'Neoplasms, Germ Cell and Embryonal', 'Polymorphism, Single Nucleotide', 'Risk Factors', 'Testicular Neoplasms', 'United States'] | 18,413,775 | [['B01.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.365'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.334.968', 'D06.472.699.337', 'D12.644.548.387', 'D12.776.395.439'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A low blood lymphocyte count is associated with an expansion of activated cytotoxic lymphocytes in patients with B-cell chronic lymphocytic leukaemia. | In order to determine the relationships between CD2+ lymphocyte subpopulations and tumour mass, the immunophenotype of natural killer (NK) cells and T lymphocyte subsets was studied in 56 B-chronic lymphocytic leukaemia (B-CLL) patients and 38 healthy subjects. The patients were classified according to their blood lymp... | ['Adult', 'Aged', 'Antigens, CD', 'CD4-CD8 Ratio', 'Female', 'Humans', 'Immunophenotyping', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Lymphocyte Activation', 'Lymphocyte Subsets', 'Male', 'Middle Aged', 'T-Lymphocytes, Cytotoxic'] | 9,293,856 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['E01.370.225.500.195.107.595.500.150.160', 'E01.370.225.625.107.595.500.150.160', 'E05.200.500.195.107.595.500.150.160', 'E05.200.625.107.595.500.150.160', 'E05.242.195.107.595.500.150.160', 'G04.140.107.595.500.150.160', 'G09.188.105.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relationship between hunger-satiety feelings and various metabolic parameters in women with obesity during controlled weight loss. | OBJECTIVE: Satiety plays an important role in weight control. The meaning of fasting hormone levels and satiety feelings, and how post-absorptive changes after meals high in carbohydrate regulate appetite remains to be demonstrated.RESEARCH METHODS AND PROCEDURES: Prospective metabolic study with 25 non-diabetic obese ... | ['Adult', 'Blood Glucose', 'Cholecystokinin', 'Energy Intake', 'Fasting', 'Female', 'Food', 'Humans', 'Hunger', 'Insulin', 'Middle Aged', 'Multivariate Analysis', 'Obesity', 'Oxygen Consumption', 'Prospective Studies', 'Satiation', 'Weight Loss'] | 9,618,127 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['D06.472.317.152', 'D12.644.120'], ['G07.203.650.240.340'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.293.391', 'G07.203.650.390', 'G10.261.390'], ['D06.472.699... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Hairless mouse skin is limited as a model for assessing the effects of penetration enhancers in human skin. | The permeability coefficient of 5-fluorouracil through human abdominal and hairless mouse skins was used as an indicator of the relative effects of 12-h pretreatment of the skins with either penetration-enhancer mixtures [including laurocapram (Azone), decylmethylsulfoxide, oleic acid, and propylene glycol] or saline (... | ['Animals', 'Azepines', 'Dimethyl Sulfoxide', 'Fluorouracil', 'Humans', 'Male', 'Mice', 'Mice, Hairless', 'Oleic Acid', 'Oleic Acids', 'Permeability', 'Propylene Glycol', 'Propylene Glycols', 'Skin', 'Skin Absorption', 'Sodium Chloride'] | 3,373,011 | [['B01.050'], ['D03.383.066'], ['D02.886.640.150'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.200', 'B01.050.150.900.649.313.992.635.505.500.400.200', 'B01.050.150.900.649.313.992.635.505.500.550.230'], ['D10.251.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hilar cholangiocarcinoma: thin-section spiral CT findings with cholangiographic correlation. | Hilar cholangiocarcinoma, a highly lethal tumor, is difficult to diagnose with conventional computed tomography (CT) because of its small size. Spiral CT allows more effective evaluation of these small lesions and better demonstrates the status of the hepatic arterial or portal venous circulation. Among 27 patients wit... | ['Adult', 'Aged', 'Bile Duct Neoplasms', 'Bile Ducts, Intrahepatic', 'Cholangiocarcinoma', 'Cholangiography', 'Cholestasis, Intrahepatic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed'] | 9,397,459 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.274.120.250', 'C06.130.120.120', 'C06.130.320.120', 'C06.301.120.250'], ['A03.159.183.158', 'A03.620.150'], ['C04.557.470.200.025.450'], ['E01.370.350.700.715.200', 'E01.370.372.200'], ['C06.130.120.135.250', 'C06.552.150'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
7 alpha-Methylnorethindrone enanthate 10 beta-hydroperoxide: isolation and characterization. | 10 beta-Hydroperoxy-7 alpha-methylnorethindrone 17-heptanoate (II), a product of allylic autoxidation of 7 alpha-methylnorethindrone enanthate (I), has been isolated and characterized. The synthesis of the hydroperoxide (II) from the 3-ethylene ketal of 7 alpha-methylnorethynodrel (III) was achieved. Esterification of ... | ['Animals', 'Chemical Phenomena', 'Chemistry', 'Estrus', 'Female', 'Norethindrone', 'Oxidation-Reduction', 'Pregnancy', 'Progestins', 'Rats', 'Vagina'] | 6,689,617 | [['B01.050'], ['G02'], ['H01.181'], ['G08.686.195.500'], ['D04.210.500.668.651.693.651'], ['G02.700', 'G03.295.531'], ['G08.686.784.769'], ['D27.505.696.399.472.858'], ['B01.050.150.900.649.313.992.635.505.700'], ['A05.360.319.779']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Splanchnic circulation following coeliac plexus block. | Both the capacitance vessels and the resistance vessels of the splanchnic area are innervated by the sympathetic nerve fibers. We investigated the effect of abdominal visceral sympathectomy on splanchnic circulation, and the effect of altered splanchnic circulation on systemic circulation in ten mongrel dogs. Abdominal... | ['Animals', 'Autonomic Nerve Block', 'Celiac Plexus', 'Dogs', 'Female', 'Male', 'Splanchnic Circulation'] | 3,394,483 | [['B01.050'], ['E03.155.086.711.299', 'E04.525.210.550.500'], ['A08.800.050.050.150', 'A08.800.800.060.150'], ['B01.050.150.900.649.313.750.250.216.200'], ['G09.330.100.881']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of Isometric Brain-Body Size Scaling on the Complexity of Monoaminergic Neurons in a Minute Parasitic Wasp. | Trichogramma evanescens parasitic wasps show large phenotypic plasticity in brain and body size, resulting in a 5-fold difference in brain volume among genetically identical sister wasps. Brain volume scales linearly with body volume in these wasps. This isometric brain scaling forms an exception to Haller's rule, whic... | ['Animals', 'Biological Evolution', 'Body Size', 'Brain', 'Dopaminergic Neurons', 'Nervous System', 'Neurons', 'Phenotype', 'Receptors, Biogenic Amine', 'Serotonergic Neurons', 'Wasps'] | 28,478,445 | [['B01.050'], ['G05.045', 'G16.075'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['A08.186.211'], ['A08.675.278', 'A11.671.270'], ['A08'], ['A08.675', 'A11.671'], ['G05.695'], ['D12.776.543.750.670'], ['A08.675.895', 'A11.671.895'], ['B01.050.500.131.617.720.500.500.875.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular identification of the wheat male fertility gene Ms1 and its prospects for hybrid breeding. | The current rate of yield gain in crops is insufficient to meet the predicted demands. Capturing the yield boost from heterosis is one of the few technologies that offers rapid gain. Hybrids are widely used for cereals, maize and rice, but it has been a challenge to develop a viable hybrid system for bread wheat due to... | ['Carrier Proteins', 'Fertility', 'Genes, Plant', 'Genetic Complementation Test', 'Hybridization, Genetic', 'Plant Breeding', 'Plant Proteins', 'Pollen', 'Triticum'] | 29,021,581 | [['D12.776.157'], ['G08.686.210'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['E05.393.281.526'], ['E05.820.150.390', 'G05.090.390'], ['J01.040.227.500'], ['D12.776.765'], ['A18.024.249.500.249.500'], ['B01.650.940.800.575.912.250.822.918']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Analysis of the genome content of Lactococcus garvieae by genomic interspecies microarray hybridization. | BACKGROUND: Lactococcus garvieae is a bacterial pathogen that affects different animal species in addition to humans. Despite the widespread distribution and emerging clinical significance of L. garvieae in both veterinary and human medicine, there is almost a complete lack of knowledge about the genetic content of thi... | ['Comparative Genomic Hybridization', 'Computational Biology', 'Computer Simulation', 'DNA, Bacterial', 'Databases, Genetic', 'Genome, Bacterial', 'Lactococcus', 'Oligonucleotide Array Sequence Analysis', 'Species Specificity', 'Streptococcus pneumoniae'] | 20,233,401 | [['E05.393.285.240', 'E05.393.520.500', 'E05.393.661.187'], ['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['D13.444.308.212'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G05.360.340.358.207'], ['B03.353.750.737.500', 'B03.510.400.800.500', 'B03.510.550.737.500'], ['E05.393.661.640', 'E05.393.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors. | We have reported previously that substitution of the transmembrane domain of the insulin receptor with that of the erbB-2 oncogene (IRerbV-->E) results in constitutive activation of the insulin receptor kinase. Compared to NIH3T3 cells overexpressing wild-type insulin receptors (IRwt), cells overexpressing IRerbV-->E d... | ['3T3 Cells', 'Adaptor Proteins, Signal Transducing', 'Adaptor Proteins, Vesicular Transport', 'Animals', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Enzyme Activation', 'Epidermal Growth Factor', 'ErbB Receptors', 'GRB2 Adaptor Protein', 'Insulin', 'Insulin Receptor Substrate Proteins', 'Mice', 'Mitogen-Activated... | 8,910,437 | [['A11.251.210.100', 'A11.329.228.100'], ['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.776.543.990.150'], ['B01.050'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['G02.111.263', 'G03.328'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distinct functional and temporal requirements for zebrafish Hdac1 during neural crest-derived craniofacial and peripheral neuron development. | The regulation of gene expression is accomplished by both genetic and epigenetic means and is required for the precise control of the development of the neural crest. In hdac1(b382) mutants, craniofacial cartilage development is defective in two distinct ways. First, fewer hoxb3a, dlx2 and dlx3-expressing posterior bra... | ['Animals', 'Branchial Region', 'Cell Differentiation', 'Craniofacial Abnormalities', 'Embryo, Nonmammalian', 'Face', 'Histone Deacetylase 1', 'Hydroxamic Acids', 'Hyoid Bone', 'Mandible', 'Mutation', 'Neural Crest', 'Neurons', 'Peripheral Nervous System', 'Phenotype', 'Skull', 'Stem Cells', 'Sympathetic Nervous System... | 23,667,588 | [['B01.050'], ['A16.142'], ['G04.152'], ['C05.660.207', 'C16.131.621.207'], ['A13.350', 'A16.331'], ['A01.456.505'], ['D08.811.277.087.520.500.100', 'D08.811.277.087.520.750.100', 'D08.811.600.620.100', 'D08.811.600.795.100'], ['D02.092.570.394', 'D02.241.511.372'], ['A02.835.232.409'], ['A02.835.232.781.324.502.632', ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Similar serum plant sterol responses of human subjects heterozygous for a mutation causing sitosterolemia and controls to diets enriched in plant sterols or stanols. | OBJECTIVE: We investigated the serum phytosterol responses of heterozygous relatives of sitosterolemia patients to diets enriched in phytosterols or stanols.DESIGN: Randomized double-blind crossover design.SETTING: Muenster, Germany.SUBJECTS: Eight heterozygous and 13 control subjects were recruited. One heterozygote a... | ['Adult', 'Anticholesteremic Agents', 'Cholesterol', 'Cross-Over Studies', 'Double-Blind Method', 'Esters', 'Female', 'Germany', 'Humans', 'Male', 'Margarine', 'Phytosterols', 'Sitosterols', 'Sterols'] | 17,228,349 | [['M01.060.116'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D02.241.400'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Blood pressure indexes and end-stage renal disease risk in adults with chronic kidney disease. | BACKGROUND: Few studies have compared different blood pressure (BP) indexes for end-stage renal disease (ESRD) risk among individuals with chronic kidney disease.METHODS: We examined the relationship between systolic BP (SBP), diastolic BP (DBP), pulse pressure (PP) and mean arterial pressure (MAP) and ESRD risk among ... | ['Aged', 'Antihypertensive Agents', 'Blood Pressure', 'Female', 'Glomerular Filtration Rate', 'Humans', 'Hypertension', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Renal Insufficiency, Chronic', 'Risk Factors', 'Southeastern United States'] | 22,573,012 | [['M01.060.116.100'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['E05.318.740.500.700', 'E05.318.740.600.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Endothelial Senescence Contributes to Heart Failure With Preserved Ejection Fraction in an Aging Mouse Model. | BACKGROUND: Because of global aging, the prevalence of heart failure with preserved ejection fraction (HFpEF) continues to rise. Although HFpEF pathophysiology remains incompletely understood, endothelial inflammation is stated to play a central role. Cellular senescence is a process of cellular growth arrest linked wi... | ['Aging', 'Animals', 'Cellular Senescence', 'Disease Models, Animal', 'Echocardiography', 'Endothelium, Vascular', 'Female', 'Heart Failure', 'Mice', 'Stroke Volume'] | 28,611,124 | [['G07.345.124'], ['B01.050'], ['G04.043'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A07.015.700.500', 'A10.272.491.355'], ['C14.280.434'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.370.380.150.700', 'G09.330.380.124.882']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stroke survivors in Nigeria: A door-to-door prevalence survey from the Niger Delta region. | The burden of stroke has been projected to increase in low-and middle-income countries due to the ongoing epidemiological transition. However, community-based stroke prevalence studies are sparse in sub-Saharan Africa particularly in Nigeria. This study aimed to provide a comparative estimate of the prevalence of strok... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Chi-Square Distribution', 'Cross-Sectional Studies', 'Female', 'Health Surveys', 'Humans', 'Male', 'Middle Aged', 'Niger', 'Prevalence', 'Rural Population', 'Stroke', 'Young Adult'] | 28,017,225 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.3... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Histochemical studies on the content of plasmin in the normal and hyperplastic prostate (author's transl)]. | The content of plasmin is significantly reduced in the benign prostatic hypertrophy compared to the normal prostate. Histochemically plasmin is demonstrable by a combined incubation of substrate and inhibitor for plasmin. Plasmin is localized in the connective tissue and its function is to regulate the turnover of glyc... | ['Fibrinolysin', 'Histocytochemistry', 'Humans', 'Male', 'Prostate', 'Prostatectomy', 'Prostatic Hyperplasia'] | 70,942 | [['D08.811.277.656.300.760.330', 'D08.811.277.656.959.350.330'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.360.444.575', 'A10.336.707'], ['E04.950.774.860.625']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Incidence and Implications of Left Ventricular Distention During Venoarterial Extracorporeal Membrane Oxygenation Support. | Left ventricular distention (LVD) during venoarterial extracorporeal membrane oxygenation (VA-ECMO) support is increasingly recognized but seldom reported in the literature. The current study defined LVD as not present (LVD-); subclinical (LVD+, evidence of pulmonary edema on chest radiograph AND pulmonary artery diast... | ['Adult', 'Aged', 'Cardiopulmonary Resuscitation', 'Decompression, Surgical', 'Extracorporeal Membrane Oxygenation', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Ventricular Function, Left'] | 28,422,817 | [['M01.060.116'], ['M01.060.116.100'], ['E02.365.647.110'], ['E04.188'], ['E02.880.301', 'E04.292.451'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
National health insurance reconsidered: dilemmas and opportunities. | Changing social and economic constraints are precipitating a reformulation of the role of government in the provision of social welfare services. The authors conclude that government intervention in the health sector is bound to expand rather than contract because centralization is the key to reconciling otherwise dive... | ['Health Expenditures', 'Health Policy', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Medicare', 'National Health Insurance, United States', 'Politics', 'United States'] | 10,313,101 | [['N03.219.151.450', 'N05.300.385'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.420', 'N05.300.450'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.706.615.696'], ['N03.219.521.576.343.900', 'N03.349.550.610'], ['I01.738... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Regional assignment of catalase (CAT) gene to band 11p13. Association with the aniridia-Wilms' tumor-Gonadoblastoma (WAGR) complex. | A gene dosage effect for catalase (CAT) was investigated in three individuals : one with 11p13 deletion, aniridia, ambiguous genitalla, and gonadoblastoma ; one trisomic for 11p with the exception of 11p13; and one trisomic for 11p13. Results were compatible with the assignment of CAT to 11p13 and its linkage with the ... | ['Adolescent', 'Catalase', 'Child', 'Chromosome Mapping', 'Chromosomes, Human, 6-12 and X', 'Clinical Enzyme Tests', 'Dysgerminoma', 'Female', 'Humans', 'Infant', 'Iris', 'Kidney Neoplasms', 'Male', 'Neoplasms, Multiple Primary', 'Wilms Tumor'] | 6,252,821 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM. | Integrin alpha M (ITGAM; CD11b) is a component of the macrophage-1 antigen complex, which mediates leukocyte adhesion, migration and phagocytosis as part of the immune system. We previously identified a missense polymorphism, rs1143679 (R77H), strongly associated with systemic lupus erythematosus (SLE). However, the mo... | ['Alleles', 'Antigens, Nuclear', 'CD11b Antigen', 'Chromatin', 'Continental Population Groups', 'DNA-Binding Proteins', 'Female', 'Fibrinogen', 'Gene Expression Regulation', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Humans', 'Ku Autoantigen', 'Lupus Erythematosus, Systemic', 'Male', 'Monocytes', 'NF-kappa... | 24,608,226 | [['G05.360.340.024.340.030'], ['D12.776.660.625', 'D23.050.290'], ['D12.776.395.550.200.074.750', 'D12.776.543.550.200.093.750', 'D12.776.543.750.705.408.100.150', 'D12.776.543.750.705.833.062', 'D23.050.301.350.074.049'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['M01.686.508'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Group A rotavirus and bacterial agents associated with diarrhoea-induced hospitalisations in children below 5 years of age in Jammu. | Out of 210 faecal samples collected from children below 5 years attending different hospitals in Jammu and exhibiting clinical signs of diarrhoea, 41.9% samples were found positive for group A rotavirus by RNA-PAGE. Escherichia coli isolated in the study belonged to nine serogroups, out of which O69 was most frequent, ... | ['Bacterial Typing Techniques', 'Child, Preschool', 'Diarrhea', 'Feces', 'Female', 'Genotype', 'Gram-Negative Bacteria', 'Gram-Negative Bacterial Infections', 'Hospitalization', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Rotavirus', 'Rotavirus Infections', 'Serotyping'] | 24,399,390 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['M01.060.406.448'], ['C23.888.821.214'], ['A12.459'], ['G05.380'], ['B03.440'], ['C01.150.252.400'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['B04.820.223.719.790'], ['C01.925.782.791... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Giardiasis in dairy calves: effects of fenbendazole treatment on intestinal structure and function. | Twelve Giardia duodenalis-infected Holstein dairy calves were allocated into a treatment (n=6) and placebo group (n=6) according to pre-study faecal cyst counts. Calves in the treatment group received an oral dose of 5 mg/kg fenbendazole once daily for 3 days, while placebo calves received a sterile saline solution. Ca... | ['Animals', 'Antinematodal Agents', 'Cattle', 'Cattle Diseases', 'Dairying', 'Drug Administration Schedule', 'Female', 'Fenbendazole', 'Giardia lamblia', 'Giardiasis', 'Intestines', 'Microscopy, Electron', 'Structure-Activity Relationship'] | 11,165,274 | [['B01.050'], ['D27.505.954.122.250.075.080'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['J01.040.246'], ['E02.319.283'], ['D02.241.081.251.320', 'D03.633.100.103.450'], ['B01.237.385.400'], ['C01.610.432.481', 'C01.610.752.400', 'C06.405.469.452.481'], ['A03.556.124'], ['E01.370.350.515.402', 'E05.595.402... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pediatric cervical spine fractures: predominantly subtle presentation. | Previous description of cervical spine fractures in children have emphasized high mortality injuries to the upper cervical vertebra. Our experience suggests a much wider spectrum of injury. The medical records of all children with cervical spine fractures admitted to Children's Hospital between January 1, 1985 and Dece... | ['Adolescent', 'Cervical Vertebrae', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Incidence', 'Male', 'Spinal Fractures', 'Traction'] | 1,919,996 | [['M01.060.057'], ['A02.835.232.834.151'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C26.117.500.500', 'C26.404.812'], ['E04.555.720']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adenosine A2a receptors increase arterial endothelial cell nitric oxide. | BACKGROUND: Adenosine is a potent vasodilator of vascular smooth muscle. Endothelium-derived nitric oxide (NO) elicits vasodilation. We have previously reported that adenosine stimulates the production of NO from porcine carotid arterial endothelial cells (PCAEC) via a receptor-mediated mechanism. This study was to det... | ['Adenosine', "Adenosine-5'-(N-ethylcarboxamide)", 'Animals', 'Carotid Arteries', 'Cells, Cultured', 'Endothelium, Vascular', 'Humans', 'Iliac Artery', 'Nitric Oxide', 'Phenethylamines', 'Purinergic P1 Receptor Agonists', 'Purinergic P1 Receptor Antagonists', 'Quinazolines', 'Receptor, Adenosine A2A', 'Receptors, Purin... | 9,878,338 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D03.633.100.759.590.138.025', 'D13.570.583.138.025', 'D13.570.800.096.250'], ['B01.050'], ['A07.015.114.186'], ['A11.251'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.444'], ['D01.339.387', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Motivations and demographics of I-6 and traditional 5+2 cardiothoracic surgery resident applicants: insights from an academic training program. | BACKGROUND: The introduction of the integrated 6-year cardiothoracic surgery residency (I-6) has changed the training paradigm for future cardiothoracic surgeons. Increased interest in these programs emphasizes the need for an understanding of the applicant pool and of their differences from the traditional trainee (5+... | ['Adult', 'Career Choice', 'Demography', 'Education, Medical', 'Female', 'Humans', 'Internship and Residency', 'Job Application', 'Male', 'Motivation', 'Thoracic Surgery', 'United States'] | 25,085,556 | [['M01.060.116'], ['F02.463.785.373.346.400'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['I02.358.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['N04.452.677.400'], ['F01.658', 'F01.752.543.500.750'], ['H02.403.810.803'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Influence of bovine lactoferrin on expression of presentation molecules on BCG-infected bone marrow derived macrophages. | The current vaccine for tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is an attenuated strain of Mycobacterium bovis bacillus Calmette-Guerin (BCG). BCG has proven to be effective in children, however, efficacy wanes in adulthood. Lactoferrin, a natural protein with immunomodulatory properties, is a po... | ['Animals', 'B7-1 Antigen', 'B7-2 Antigen', 'Bone Marrow Cells', 'CD40 Antigens', 'Cattle', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Flow Cytometry', 'Gene Expression', 'Genes, MHC Class II', 'Lactoferrin', 'Macrophages', 'Mice', 'Mycobacterium bovis'] | 18,486,627 | [['B01.050'], ['D12.776.467.150.100', 'D12.776.543.095.100', 'D23.050.301.285.100', 'D23.529.168.100'], ['D12.776.465.500', 'D12.776.467.150.200', 'D12.776.543.095.200', 'D23.050.301.285.200', 'D23.529.168.200'], ['A11.148', 'A15.378.316'], ['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.264.051.140... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The influence of angiotensin-(1-7) Mas receptor agonist (AVE 0991) on mitochondrial proteome in kidneys of apoE knockout mice. | Excessive action of angiotensin II on mitochondria has been shown to play an important role in mitochondrial dysfunction, a common feature of atherogenesis and kidney injury. Angiotensin-(1-7)/Mas receptor axis constitutes a countermeasure to the detrimental effects of angiotensin II on AT1 receptors. The aim of the st... | ['Animals', 'Antioxidants', 'Apolipoproteins E', 'Apoptosis Regulatory Proteins', 'Atherosclerosis', 'Imidazoles', 'Inflammation Mediators', 'Kidney', 'Mice', 'Mice, Knockout', 'Mitochondrial Proteins', 'Proteome', 'Proto-Oncogene Proteins', 'Receptor, Angiotensin, Type 1', 'Receptors, G-Protein-Coupled'] | 23,988,828 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['D12.644.360.075', 'D12.776.476.075'], ['C14.907.137.126.307'], ['D03.383.129.308'], ['D23.469'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel assessment of acute lung injury by in vivo near-infrared spectroscopy. | We investigated the feasibility and validity of near-infrared (NIR) spectroscopy for evaluation of acute lung injury (ALI). In an in vitro model simulating the spectrophotometric characteristics of the lung, NIR spectroscopy could precisely detect changes in water volume, suggesting its ability to assess the extent of ... | ['Animals', 'Disease Models, Animal', 'Extravascular Lung Water', 'Hemoglobins', 'Lung', 'Male', 'Oleic Acid', 'Pulmonary Edema', 'Rats', 'Rats, Wistar', 'Respiratory Distress Syndrome', 'Spectroscopy, Near-Infrared'] | 10,390,418 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A12.207.270.300'], ['D12.776.124.400', 'D12.776.422.316.762'], ['A04.411'], ['D10.251.355.325.600.525'], ['C08.381.742'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['C08.381.840', 'C08.618.840'], ['E01.370... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Advances in the diagnosis and therapy of bone tumors with special reference to modern surgical possibilities]. | Progress in the diagnosis of bone tumors is primarily to be seen in the possibilities of exact radiological demonstration, the differentiation of morphological characteristics of tumor growthdynamics (tumor vessels) and in the possibilities of modern nuclear methods, which provide preoperative information on the metabo... | ['Bone Neoplasms', 'Breast Neoplasms', 'Diagnosis, Differential', 'Femur', 'Giant Cell Tumors', 'Hip', 'Humans', 'Immunity', 'Neoplasm Metastasis', 'Osteosarcoma', 'Radiography', 'Radius'] | 1,063,729 | [['C04.588.149', 'C05.116.231'], ['C04.588.180', 'C17.800.090.500'], ['E01.171'], ['A02.835.232.043.150'], ['C04.557.450.565.380'], ['A01.378.610.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['C04.697.650', 'C23.550.727.650'], ['C04.557.450.565.575.650', 'C04.557.450.795.620'], ['E01.370.350.700... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Covalent binding of [14C]methoxychlor metabolite(s) to rat liver microsomal components. | [14C]Methoxychlor was incubated with NADPH-fortified liver microsomes from male rats, and covalent binding to microsomal components was determined. The binding process was markedly enhanced when microsomes from phenobarbital-treated rats were employed. However, when microsomes from methylcholanthrene-treated rats were ... | ['Animals', 'Binding Sites', 'Binding, Competitive', 'In Vitro Techniques', 'Male', 'Methoxychlor', 'Microsomes, Liver', 'Rats', 'Rats, Inbred Strains'] | 6,857,671 | [['B01.050'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['E05.481'], ['D02.455.526.439.610'], ['A11.284.835.540.541'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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