Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Stilbene dimers from the lianas of Gnetum hainanense. | Five stilbene dimers, gnetuhainins F-J, were isolated together with gnetulin, rhapontigenin, isorhapontigenin and gnetol from the lianas of Gnetum hainanense C. Y. Cheng. Their structures and stereochemistry have been established on the basis of spectral evidence, especially 2D NMR spectroscopic techniques. | ['Molecular Structure', 'Plants', 'Spectrum Analysis', 'Stilbenes'] | 11,014,282 | [['G02.111.570', 'G02.466'], ['B01.650'], ['E05.196.867'], ['D02.455.426.559.389.150.700']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thoracic epidural catheter placement via the caudal approach in infants by using electrocardiographic guidance. | UNLABELLED: We examined the success of inserting epidural catheters via the caudal route in infants by using electrocardiographic guidance. A case series of 20 patients with thoracic epidural analgesia was studied. After the induction of general anesthesia, an 18-gauge IV catheter was inserted into the caudal space to ... | ['Anesthesia, Epidural', 'Child, Preschool', 'Electrocardiography', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Prospective Studies'] | 12,145,046 | [['E03.155.086.131'], ['M01.060.406.448'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
New polar constituents in the pupae of the silkworm Bombyx mori L. (II): developmental changes of the constituents. | A correlation between the quantitative changes in L-methionine analogs, the ratio of D-serine/L-serine during the pupal stage, and metamorphosis was observed. The glycoside appearing at low blood sugar values during the pupal stage was isolated and characterized as D-glucosyl-L-tyrosine. (1)H-NMR indicated the appearan... | ['Animals', 'Bombyx', 'Female', 'Magnetic Resonance Spectroscopy', 'Male', 'Methionine', 'Pupa', 'Trehalose', 'Tyrosine'] | 20,944,408 | [['B01.050'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['E05.196.867.519'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['B05.500.700', 'G07.345.500.550.500.700'], ['D09.698.365.900', 'D09.698.629.305.880', 'D09.947.750.880'], ['D12.125.072.050.875']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preoperative liver volumetry: how does the slice thickness influence the multidetector computed tomography- and magnetic resonance-liver volume measurements? | OBJECTIVE: The purpose was to investigate the influence of slice thickness on multidetector computed tomography (MDCT)- and magnetic resonance (MR)-based liver volumetry.MATERIALS AND METHODS: Twenty patients who underwent liver surgery were imaged with either a 64-slice MDCT (n = 10) or a 1.5-T MR scanner (n = 10). Mu... | ['Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Anatomy, Cross-Sectional', 'Female', 'Hepatectomy', 'Humans', 'Image Enhancement', 'Imaging, Three-Dimensional', 'Liver', 'Liver Diseases', 'Male', 'Middle Aged', 'Organ Size', 'Preoperative Care', 'Radiographic Image Interpretation, Computer-Assisted', 'Reproducibi... | 19,478,632 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['H01.158.100.185'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.400', 'L01.224.308.410'], ['A03.620'], ['C06.552'], ['M01.060.116.630'], ['E01.370.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Experimental and ecological implications of evening bird surveys in stream-riparian ecosystems. | Stream-riparian ecosystems are dynamic and complex entities that can support high levels of bird assemblage abundance and diversity. The myriad patches (e.g., aquatic, floodplain, riparian) found in the riverscape habitat mosaic attract a unique mixture of aquatic, semiaquatic, riparian, and upland birds, each uniquely... | ['Animals', 'Biodiversity', 'Birds', 'Data Collection', 'Ecosystem', 'Environmental Monitoring', 'Periodicity', 'Rivers', 'Trees'] | 19,506,939 | [['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['B01.050.150.900.248'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.910.645', 'G07.180.562'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Reproductive and teratogenic effects of sufentanil and alfentanil in Sprague-Dawley rats. | The reproductive and teratogenic effects of sufentanil and alfentanil were studied in a total of 168 Sprague-Dawley rats in two separate experiments. Either sufentanil (10, 50, or 100 micrograms.kg-1.day-1) or alfentanil (8 mg.kg-1.day-1) were administered continuously from day 5 through day 20 of pregnancy using subcu... | ['Abnormalities, Drug-Induced', 'Alfentanil', 'Anesthetics', 'Animals', 'Female', 'Fentanyl', 'Pregnancy', 'Rats', 'Rats, Inbred Strains', 'Reproduction', 'Sufentanil'] | 2,963,565 | [['C16.131.042'], ['D03.383.621.265.100'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['B01.050'], ['D03.383.621.265'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G08.686.784'], ['D03.383.621.265.900']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Commotio cordis--a report of two similar cases. | Commotio cordis is a rare and fatal mechano-electric arrhythmogenic syndrome, occurring mainly during sports activities. The present study describes two similar cases of sudden death caused by commotio cordis associated with homicide. The two decedents were both 15-year-old male teenagers. Both collapsed within several... | ['Adolescent', 'Commotio Cordis', 'Death, Sudden', 'Humans', 'Male', 'Myocardium', 'Thoracic Injuries', 'Violence', 'Wounds, Nonpenetrating'] | 23,082,987 | [['M01.060.057'], ['C14.280.067.441', 'C26.891.375.750.500', 'C26.974.250.875.500'], ['C23.550.260.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['C26.891'], ['I01.198.240.856', 'I01.880.735.900'], ['C26.974']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Process, pitfalls and profits: lessons from interviewing New Zealand policy-makers. | Little has been written about interviewing policy-makers in health promotion and public health research. This article explores the process, pitfalls and profits of semi-structured interviews with policy-makers in 10 research projects conducted in New Zealand. Key members of each research team were surveyed about their ... | ['Administrative Personnel', 'Health Policy', 'Health Promotion', 'Health Services Research', 'Humans', 'Interviews as Topic', 'New Zealand', 'Policy Making', 'Public Health', 'Qualitative Research'] | 27,543,932 | [['M01.526.070'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['I02.233.332.445', 'N02.421.726.407.579'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
[Luteinized cystic ovarian hyperplasia during a normal pregnancy]. | Hyperreactio luteinalis (HRL) is rarely observed in normal pregnancy. Its clinical spectrum consists of benign development of often bilateral lutein cysts and may be revealed by an overproduction of androgens. HRL is more often in relation with an excessive production of human chorionic gonadotropin (hCG) either in tro... | ['Adult', 'Androgens', 'Chorionic Gonadotropin', 'Diagnosis, Differential', 'Estradiol', 'Female', 'Follicle Stimulating Hormone', 'Humans', 'Hyperplasia', 'Infant, Newborn', 'Luteinization', 'Luteinizing Hormone', 'Male', 'Ovarian Cysts', 'Ovary', 'Ovulation Induction', 'Pregnancy', 'Pregnancy Complications', 'Pregnan... | 12,843,886 | [['M01.060.116'], ['D27.505.696.399.472.161'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['E01.171'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Density functional theory studies on the conversion of hydroxyheme to iron-verdoheme in the presence of dioxygen. | Detailed insight into the second step of heme degradation by heme oxygenase, oxophlorin to verdoheme and biliverdin, is presented. Density functional theory methods are reported for the conversion of oxophlorin to verdoheme. Since it is currently unclear whether dioxygen binding to iron oxophlorin is followed by a redu... | ['Heme', 'Iron', 'Models, Molecular', 'Molecular Conformation', 'Oxygen', 'Porphyrins', 'Quantum Theory'] | 28,120,965 | [['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['E05.599.595'], ['G02.111.570.820'], ['D01.268.185.550', 'D01.362.670'], ['D03.383.129.578.840.500', 'D03.633.400.909.500', 'D04.345.783.500'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Noninvasive detection of coronary artery bypass graft patency by intravenous electron beam computed tomographic angiography. | This study evaluates the usefullness of intravenous electron beam computed tomographic angiography (EBA) for the detection of coronary artery bypass graft patency in 43 patients (33 men and 10 women, mean age, 65 years) who had coronary artery bypass graft surgery. EBA was performed a few days before selective bypass g... | ['Adult', 'Aged', 'Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Epigastric Arteries', 'Female', 'Graft Occlusion, Vascular', 'Humans', 'Internal Mammary-Coronary Artery Anastomosis', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Saphenous Vein', 'Sensitivity and Specificity', 'Tom... | 14,711,177 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A07.015.114.330'], ['C23.550.767.400'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acid-base status and urinary hydrogen ion excretion pattern in low-birth-weight infants receiving intravenous fat emulsion and glucose. | The acidifying effect of short-term (6-hr) infusion of intralipid was studied in 12 low-birth-weight infants by following the changes in acidbase status and urinary H+ excretion pattern. The infants received 5% or 10% glucose as a base-line calorie supply. Intravenous fat emulsion induced a transient metabolic acidosis... | ['Acid-Base Equilibrium', 'Ammonia', 'Bicarbonates', 'Dietary Fats', 'Gluconeogenesis', 'Glucose', 'Humans', 'Hydrogen', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Infant, Premature', 'Parenteral Nutrition'] | 829,839 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['D01.362.075', 'D01.625.050'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['G02.111.158.500', 'G03.191.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Developing a systematic search strategy related to people with disability: A brief report testing the utility of proposed disability search terms in a search about opioid use. | BACKGROUND: The varied use of the term "disability" in the scientific literature makes it challenging to conduct systematic reviews of health issues among people with disability. Utilizing general disability search terms has been suggested as an efficient way to ensure a broad capture of the literature related to disab... | ['Abstracting and Indexing', 'Analgesics, Opioid', 'Databases, Factual', 'Disabled Persons', 'Humans', 'Muscular Atrophy, Spinal', 'Publications', 'Search Engine'] | 30,470,478 | [['L01.453.245.100'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['M01.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.854.468', 'C10.574.562.500', 'C10.668.467.500'],... | ['Information Science [L]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Eating disorders and sexual function]. | Women suffering from eating disorders, present considerable retardation and difficulties in their psychosexual development during adolescence. This leads to primary or secondary insufficiencies in their adult sexual life. The cause of these difficulties seems to be a series of biological, family and psychosocial factor... | ['Adult', 'Behavioral Symptoms', 'Feeding and Eating Disorders', 'Female', 'Humans', 'Psychological Techniques', 'Psychotherapy', 'Sexual Behavior', 'Sexual Dysfunctions, Psychological', 'Treatment Outcome'] | 27,467,034 | [['M01.060.116'], ['F01.145.126'], ['F03.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.796', 'F04.669'], ['F04.754'], ['F01.145.802'], ['F03.835'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Morbidity of repeat transsphenoidal surgery assessed in more than 1000 operations. | UNLABELLED: OBJECT.: While transsphenoidal surgery is associated with low morbidity, the degree to which morbidity increases after reoperation remains unclear. The authors determined the morbidity associated with repeat versus initial transsphenoidal surgery after 1015 consecutive operations.METHODS: The authors conduc... | ['Adenoma', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Central Nervous System Cysts', 'Cerebrospinal Fluid Leak', 'Cerebrospinal Fluid Rhinorrhea', 'Child', 'Child, Preschool', 'Diabetes Insipidus', 'Female', 'Humans', 'Hyponatremia', 'Length of Stay', 'Male', 'Meningitis', 'Middle Aged', 'Neurosurgical Proce... | 24,834,943 | [['C04.557.470.035'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.614.250.387', 'C10.500.142', 'C10.551.240.375', 'C16.131.666.142'], ['C10.597.114', 'C10.900.300.109', 'C23.888.592.114', 'C26.915.300.225'], ['C10.597.114.750', 'C10.900.300.109.750', 'C23.888.592.114.624', ... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of 5-fluorouracil on flexor tendon repair. | This study was performed to assess the effects of a single 5-minute exposure of 5-fluorouracil (5-FU) applied topically at the time of flexor tendon repair in an attempt to reduce postoperative adhesions. The flexor digitorum profundus tendon to the long and fourth toe of Leghorn chickens was lacerated and primarily re... | ['Administration, Topical', 'Analysis of Variance', 'Animals', 'Antimetabolites, Antineoplastic', 'Biomechanical Phenomena', 'Chickens', 'Collagen', 'Disease Models, Animal', 'Fluorouracil', 'Postoperative Complications', 'Random Allocation', 'Range of Motion, Articular', 'Reference Values', 'Tendon Injuries', 'Tendons... | 10,722,815 | [['E02.319.267.120'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C22.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Vernier acuities of neurons in area 17 of cat visual cortex: their relation to stimulus length and velocity, orientation selectivity, and receptive-field structure. | The sensitivity of neurons in area 17 of the cat's visual cortex to vernier offset was expressed as the percentage reduction in response caused by the introduction of a given offset into a bar stimulus moving across the receptive field. There was a wide variation in sensitivity: in some cells response could be halved b... | ['Animals', 'Cats', 'Models, Neurological', 'Neurons', 'Photic Stimulation', 'Visual Acuity', 'Visual Cortex'] | 2,487,645 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E05.599.395.642'], ['A08.675', 'A11.671'], ['E05.723.729'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.953']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of dienogest on pain and ovarian endometrioma occurrence after laparoscopic resection of uterosacral ligaments with deep infiltrating endometriosis. | OBJECTIVE: To evaluate the effect of dienogest (DNG) in preventing the occurrence of pain and endometriomas after laparoscopic resection of uterosacral ligaments (USLs) with deep infiltrating endometriosis (DIE).STUDY DESIGN: This retrospective analysis included 126 patients who underwent laparoscopic resection of USLs... | ['Endometriosis', 'Female', 'Hormone Antagonists', 'Humans', 'Laparoscopy', 'Nandrolone', 'Ovarian Diseases', 'Pain', 'Peritoneal Diseases', 'Recurrence', 'Retrospective Studies', 'Secondary Prevention', 'Treatment Outcome'] | 28,728,071 | [['C13.351.500.163'], ['D06.347', 'D27.505.696.399.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['D04.210.500.365.415.638', 'D06.472.334.851.968.976'], ['C13.351.500.056.630', 'C19.391.630'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['C06.844'], [... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rhabdomyosarcoma of the orbit. Evaluation with MR imaging and CT. | Rhabdomyosarcoma is the most common primary orbital malignancy of childhood. It can present insidiously, mimicking other (benign) processes clinically and radiographically. CT and MR imaging are crucial in the diagnostic evaluation, treatment planning, and follow-up monitoring of the disease. Such imaging, especially w... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Contrast Media', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Gadolinium', 'Humans', 'Image Enhancement', 'Infant', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Orbital Neoplasms', 'Patient Care Planning', 'Rhabdomyosarcoma', 'Tomography, X-Ra... | 9,884,698 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['D27.505.259.500', 'D27.720.259'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Photodegradation of nalidixic and tiaprofenic acids and nifedipine in aerobic conditions. | Since nalidixic acid had been previously studied in acidic and basic media, nifedipine had been investigated in anaerobic conditions and under ultraviolet light and tiaprofenic acid had not been studied at all, their photodegradation was carried out in this laboratory under milder conditions, with methanol as the solve... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Humans', 'Nalidixic Acid', 'Nifedipine', 'Oxygen', 'Photosensitivity Disorders', 'Propionates', 'Spectrum Analysis'] | 1,822,685 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.612.500', 'D03.633.100.810.835.830.500'], ['D03.383.725.203.540'], ['D01.268.185.550', 'D01.362.670'], ['C17.800.600'], ['D02.241.081.751', 'D10.251.400.706'], ['E05.196.867... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prediction of black box warning by mining patterns of Convergent Focus Shift in clinical trial study populations using linked public data. | OBJECTIVE: To link public data resources for predicting post-marketing drug safety label changes by analyzing the Convergent Focus Shift patterns among drug testing trials.METHODS: We identified 256 top-selling prescription drugs between 2003 and 2013 and divided them into 83 BBW drugs (drugs with at least one black bo... | ['Clinical Trials as Topic', 'Data Mining', 'Drug Labeling', 'Humans', 'Information Storage and Retrieval', 'Medical Informatics', 'Models, Statistical', 'Pharmacovigilance', 'Product Surveillance, Postmarketing'] | 26,851,401 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['L01.313.500.750.280.199', 'L01.470.625'], ['E05.916.310', 'J01.576.655.750.321.400', 'J01.576.761.300.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280', 'L01.470'], ['L01.313.500'], ['E05.318.740.500', 'E05.59... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Iron status of adolescent female athletes. | To determine whether or not adolescent female athletes were more in need of routine dietary iron supplements than their nonathlete peers, the iron status of 32 athletes and 31 nonathletes was assessed. The athletes were track-team members in the middle of their season. Hemoglobin, transferrin saturation, and serum ferr... | ['Adolescent', 'African Americans', 'Anemia, Hypochromic', 'Diet', 'European Continental Ancestry Group', 'Female', 'Ferritins', 'Hemoglobins', 'Humans', 'Iron', 'Risk', 'Track and Field', 'Transferrin'] | 4,044,370 | [['M01.060.057'], ['M01.686.508.100.100', 'M01.686.754.100'], ['C15.378.071.196'], ['G07.203.650.240'], ['M01.686.508.400'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.41... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors. | In this study we describe a new angiotensin antagonist [Asp1-Arg2-Val3-Tyr4-Ile5-His6-D-Ala7, (A-779)] selective for the heptapeptide angiotensin-(1-7) [Ang-(1-7)]. A-779 blocked the antidiuretic effect of Ang-(1-7) in water-loaded rats and the changes in blood pressure produced by Ang-(1-7) microinjection into the dor... | ['Adrenal Glands', 'Amino Acid Sequence', 'Angiotensin I', 'Angiotensin II', 'Angiotensin Receptor Antagonists', 'Animals', 'Blood Pressure', 'Diuresis', 'Female', 'Heart Rate', 'In Vitro Techniques', 'Injections, Intraventricular', 'Male', 'Medulla Oblongata', 'Molecular Sequence Data', 'Muscle Contraction', 'Muscle, ... | 7,850,477 | [['A06.300.071'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D06.472.699.094.075', 'D12.644.400.070.075', 'D12.644.456.073.021', 'D12.644.548.058.075', 'D12.776.631.650.070.075', 'D23.469.050.050.025'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Long-term retention assessment after simulation-based-training of pediatric procedural skills among adult emergency physicians: a multicenter observational study. | BACKGROUND: One of the primary goals of simulation-based education is to enable long-term retention of training gains. However, medical literature has poorly contributed to understanding the best timing for repetition of simulation sessions. There is heterogeneity in re-training recommendations.OBJECTIVES: This study a... | ['Adult', 'Child', 'Clinical Competence', 'Cross-Sectional Studies', 'Education, Medical, Continuing', 'Emergency Medicine', 'Female', 'Humans', 'Infant', 'Internship and Residency', 'Male', 'Physicians', 'Simulation Training', 'Task Performance and Analysis'] | 31,510,979 | [['M01.060.116'], ['M01.060.406'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I02.358.212.350', 'I02.358.399.250'], ['H02.403.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['I02.358.337.350.500', 'I02.358... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Characterization of two distinct DR beta chain alleles at the beta III locus of the DR5 haplotype: beta III alleles are highly conserved. | The HLA-DR beta region of at least two members of the DRw52 (MT2) supertypic group (DR3, DR5, DRw6, and DRw8) has recently been shown to contain three beta-chain genes--beta I, beta II, and beta III, ordered in the direction of transcription. beta III is apparently a duplication of beta I. Both beta I and beta III are ... | ['Alleles', 'Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'DNA', 'DNA Restriction Enzymes', 'Genes, MHC Class II', 'HLA-D Antigens', 'HLA-DR Antigens', 'Haplotypes', 'Humans', 'Macromolecular Substances', 'Major Histocompatibility Complex'] | 3,020,126 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.50... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin. | Human vascular endothelial cadherin (VE-cadherin, 7B4/cadherin-5) is an endothelial-specific cadherin localized at the intercellular junctions. To directly investigate the functional role of this molecule we cloned the full-length cDNA from human endothelial cells and transfected its coding region into Chinese hamster ... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Antigens, CD', 'Base Sequence', 'CHO Cells', 'Cadherins', 'Cell Adhesion', 'Cell Movement', 'Cloning, Molecular', 'Cricetinae', 'DNA Primers', 'DNA, Complementary', 'Gene Expression', 'Humans', 'Intercellular Junctions', 'Molecular Sequence Data', 'RNA, Mess... | 7,627,717 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.035', 'D23.101.100.110'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.200', 'A11.436.155'], ['D12.776.395.550.200.200', ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Beneficial effect of cilostazol-mediated neuronal repair following trimethyltin-induced neuronal loss in the dentate gyrus. | Cilostazol acts as an antiplatelet agent and has other pleiotropic effects based on phosphodiesterase-3-dependent mechanisms. We evaluated whether cilostazol would have a beneficial effect on neuronal repair following hippocampal neuronal damage by using a mouse model of trimethyltin (TMT)-induced neuronal loss/self-re... | ['Animals', 'Bromodeoxyuridine', 'CREB-Binding Protein', 'Cell Death', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Cilostazol', 'Dentate Gyrus', 'In Vitro Techniques', 'Locomotion', 'Male', 'Mice', 'Mice, Mutant Strains', 'Nerve Tissue Proteins', 'Neural Stem Cells', 'Neurons', 'Neuroprotective Ag... | 25,139,675 | [['B01.050'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['D08.811.913.050.134.415.500.575.249', 'D12.776.930.680.300'], ['G04.146'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D03.383.129.617.293', 'D03.633.100.810.069'], ['A08.186.211.180.405.200', 'A08... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Automatic Analysis of Lateral Cephalograms Based on Multiresolution Decision Tree Regression Voting. | Cephalometric analysis is a standard tool for assessment and prediction of craniofacial growth, orthodontic diagnosis, and oral-maxillofacial treatment planning. The aim of this study is to develop a fully automatic system of cephalometric analysis, including cephalometric landmark detection and cephalometric measureme... | ['Adolescent', 'Adult', 'Cephalometry', 'Child', 'Decision Trees', 'Diagnosis, Oral', 'Female', 'Humans', 'Male', 'Middle Aged', 'Radiographic Image Interpretation, Computer-Assisted', 'Radiography, Dental', 'Regression Analysis', 'Young Adult'] | 30,581,546 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['G17.162.500'], ['E06.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.158.600.680', 'E01.370.350.350.700', 'E01.370.350.700.705', 'L01.313.500.750.100.158.600.680'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Interstitial deletion of chromosome 7 detected in three unrelated patients. | Chromosome studies were carried out on three patients for the following reasons: (1) growth retardation and mental subnormality in a boy; (2) marked developmental delay in a female infant; (3) routine check on a man whose wife had a stillborn with congenital anomalies. An interstitial deletion at 7q11::7q21 was observe... | ['Abnormalities, Multiple', 'Adult', 'Child', 'Chromosome Deletion', 'Chromosomes', 'Chromosomes, Human, 6-12 and X', 'Female', 'Growth Disorders', 'Humans', 'Infant', 'Intellectual Disability', 'Karyotyping', 'Male'] | 669,706 | [['C16.131.077'], ['M01.060.116'], ['M01.060.406'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['A11.284.187.520.300.325', 'G05.360.162.520.300.325'... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Utility of echocardiography in patients with suspected mitral valve prolapse. | PURPOSE: Echocardiography has become a widely utilized test since its introduction into clinical medicine in the early 1970s. Although it has frequently been performed in patients suspected of having mitral valve prolapse (MVP), its usefulness in this setting has not been systematically studied. To investigate the use ... | ['Adult', 'Aged', 'Cardiology', 'Decision Making', 'Echocardiography', 'Female', 'Humans', 'Internal Medicine', 'Male', 'Middle Aged', 'Mitral Valve Prolapse', 'Patient Care Planning', "Practice Patterns, Physicians'", 'Prospective Studies', 'ROC Curve'] | 2,801,727 | [['M01.060.116'], ['M01.060.116.100'], ['H02.403.429.163'], ['F02.463.785.373'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429'], ['M01.060.116.630'], ['C14.280.484.400.500'], ['N04.590.233.624'], ['N04.590.374.577', 'N05.300.625'],... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Gardasil™ HPV vaccination: surveillance of vaccine usage and adherence in a military population. | OBJECTIVES: To investigate the usage patterns and adherence rates with the quadrivalent HPV (qHPV) vaccine at Naval Medical Center San Diego.METHODS: This retrospective, cross-sectional study was conducted by using AHLTA (Electronic Health Record of DoD) to identify all qHPV recipients between 2006 and 2009. Charts wer... | ['Adolescent', 'Adult', 'Child', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Military Personnel', 'Papillomavirus Vaccines', 'Patient Compliance', 'Retrospective Studies', 'Vaccination'] | 21,864,887 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.526.625'], ['D20.215.894.899.498'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Principles governing heart failure therapy re-examined relative to standard evidence-based medicine-driven guidelines. | Although all aspects of clinical work nowadays are modified by the pervading influence of evidence-based medicine (EBM) and multiplicative guidelines, not many clinicians realize that the underlying premise of EBM-driven guidelines is a particular strain of consequentialist ideology. Subservience to this ideology has t... | ['Evidence-Based Medicine', 'Heart Failure', 'Holistic Health', 'Humans', 'Outcome Assessment, Health Care', 'Practice Guidelines as Topic', "Practice Patterns, Physicians'", 'Prognosis'] | 21,932,956 | [['H02.249.750', 'H02.403.200.400'], ['C14.280.434'], ['E02.190.321', 'K01.752.667.710', 'N01.400.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['N04.761.700.350.650', 'N05.700.350.650'], ['N04.590.374.577', 'N05.300.625'], ['E01.789']] | ['Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Involvement of non-protein thiols, mitochondrial dysfunction, reactive oxygen species and p53 in honey-induced apoptosis. | Honey is a complex mixture of different biologically active constituents. Honey possesses anti-inflammatory, antioxidant and antitumor properties. Our chief investigation was to assess the honey induced apoptosis and its molecular mechanism in colon cancer cell growth inhibition. Honey exerted antiproliferative potenti... | ['Apoptosis', 'Blotting, Western', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Size', 'Flow Cytometry', 'HT29 Cells', 'Honey', 'Humans', 'Lipids', 'Membrane Potential, Mitochondrial', 'Mitochondria', 'Reactive Oxygen Species', 'Sulfhydryl Compounds', 'Tumor Suppressor Protein p53'] | 19,705,065 | [['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.325'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Piper peltatum: biomass and 4-nerolidylcatechol production. | Piper peltatum L. is used for the treatment of inflammation, malaria, and other ailments. 4-Nerolidylcatechol (4-NC) is a valuable natural product that has important anti-inflammatory, antimalarial, and antioxidant properties. 4-NC is a component of P. peltatum and P. umbellatum extracts, which are used in cosmetics. T... | ['Biomass', 'Catechols', 'Piper', 'Plant Extracts', 'Plant Roots', 'Plant Structures', 'Plants, Medicinal'] | 20,195,961 | [['G16.500.275.157.100', 'N06.230.124.100'], ['D02.455.426.559.389.657.166'], ['B01.650.940.800.575.912.250.812.666'], ['D20.215.784.500', 'D26.667'], ['A18.400'], ['A18'], ['B01.650.560']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Social avoidance and distress: its relationship to self-confidence, and needs for affiliation, change, dominance, and deference. | Introductory psychology students (N = 289) completed questionnaires to assess levels of Social Avoidance and Distress (SAD), as well as scales to measure self-confidence (S-Cfd), need for Affiliation (nAff), need for Change (nCha), need for Dominance (nDom), and need for Deference (nDef). As a function of SAD, signific... | ['Adult', 'Anxiety', 'Assertiveness', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Personality Development', 'Personality Inventory', 'Psychometrics', 'Self Concept', 'Social Adjustment', 'Social Dominance'] | 6,630,547 | [['M01.060.116'], ['F01.470.132'], ['F01.752.049'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.752.747'], ['F04.711.647.513'], ['F04.711.780'], ['F01.752.747.792'], ['F01.145.813.621'], ['F01.145.813.650']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
â-blocker prevents sudden cardiac death in patients with hemodialysis. | BACKGROUND: Beta blockers were shown to prevent SCD in cardiomyopathy or coronary artery disease patients. Dialysis patients show elevated mortality rates, predominantly due to cardiovascular disease. SCD is now one of the leading causes of death in this population. However, the prevention of SCD remains to be elucidat... | ['Adrenergic beta-Antagonists', 'Aged', 'Databases, Factual', 'Death, Sudden, Cardiac', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Renal Dialysis', 'Retrospective Studies'] | 21,996,409 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116.100'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Amplified fragment length polymorphism mapping of quantitative trait loci for malaria parasite susceptibility in the yellow fever mosquito Aedes aegypti. | The yellow fever mosquito Aedes aegypti has been the subject of extensive genetic research due to its medical importance and the ease with which it can be manipulated in the laboratory. A molecular genetic linkage map was constructed using 148 amplified fragment length polymorphism (AFLP) and six single-strand conforma... | ['Aedes', 'Animals', 'Chromosome Mapping', 'DNA Primers', 'Epistasis, Genetic', 'Insect Vectors', 'Phenotype', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Quantitative Trait Loci', 'Yellow Fever'] | 16,624,910 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['E05.393.183'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.308.207'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['G05.695'], ['E05.393.620.500'], ['G05.365.795.595'], ['G05.360.340.024.380.937'], ['C01.920.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Conditional activation of RET/PTC3 and BRAFV600E in thyroid cells is associated with gene expression profiles that predict a preferential role of BRAF in extracellular matrix remodeling. | Papillary thyroid cancers (PTC) are associated with nonoverlapping mutations of genes coding for mitogen-activated protein kinase signaling effectors (i.e., the TK receptors RET or NTRK and the signaling proteins RAS and BRAF). We examined the pattern of gene expression after activation of these oncoproteins in thyroid... | ['Animals', 'Carcinoma, Papillary', 'Cluster Analysis', 'Doxycycline', 'Extracellular Matrix', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Isoenzymes', 'Matrix Metalloproteinases', 'Proto-Oncogene Proteins B-raf', 'Proto-Oncogene Proteins c-ret', 'Rats', 'Thyroid Neoplasms'] | 16,818,623 | [['B01.050'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['A11.284.295.310'], ['E05.393.332'], ['G05.308.370'], ['D08.811.348', 'D12.776.800.300'], ['D08.811.277.656.300.480.525', 'D08.811... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Choroidal thickness measurement in children using optical coherence tomography. | PURPOSE: To measure choroidal thickness (CT) in children of various ages by using spectral optical coherence tomography with enhanced depth imaging and to investigate the association between subfoveal CT and ocular axial length, age, gender, weight, and height in children.METHODS: Healthy children were prospectively in... | ['Adolescent', 'Aging', 'Axial Length, Eye', 'Body Constitution', 'Child', 'Child, Preschool', 'Choroid', 'Healthy Volunteers', 'Humans', 'Prospective Studies', 'Refraction, Ocular', 'Sex Distribution', 'Tomography, Optical Coherence'] | 24,013,259 | [['M01.060.057'], ['G07.345.124'], ['A09.371.199', 'E01.370.600.115.100.660.500'], ['E01.370.600.115', 'G07.100'], ['M01.060.406'], ['M01.060.406.448'], ['A09.371.894.223'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.8... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Vascular endothelial growth factor (VEGF) expression in human prostate cancer: in situ and in vitro expression of VEGF by human prostate cancer cells. | PURPOSE: A growing body of literature supports the role of angiogenesis in the development and spread of a variety of human cancers including prostate cancer (Pca). Angiogenesis is controlled by chemical signals known as angiogenic factors (AF) however, little is known about angiogenesis factors in prostate cancer. We ... | ['Cells, Cultured', 'Endothelial Growth Factors', 'Humans', 'Immunohistochemistry', 'Lymphokines', 'Male', 'Prostatic Neoplasms', 'Vascular Endothelial Growth Factor A', 'Vascular Endothelial Growth Factors'] | 9,146,665 | [['A11.251'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The Effects of Boundary Conditions and Friction on the Helical Buckling of Coiled Tubing in an Inclined Wellbore. | Analytical buckling models are important for down-hole operations to ensure the structural integrity of the drill string. A literature survey shows that most published analytical buckling models do not address the effects of inclination angle, boundary conditions or friction. The objective of this paper is to study the... | ['Algorithms', 'Extraction and Processing Industry', 'Friction', 'Models, Theoretical', 'Petroleum', 'Pressure', 'Stress, Mechanical'] | 27,649,535 | [['G17.035', 'L01.224.050'], ['J01.576.655.875'], ['G01.374.618'], ['E05.599'], ['D20.345.630', 'N06.230.132.258.630'], ['G01.374.715'], ['G01.374.835']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
ã-Oryzanol-Rich Black Rice Bran Extract Enhances the Innate Immune Response. | The innate immune response is an important host primary defense system against pathogens. ã-Oryzanol is one of the nutritionally important phytoceutical components in rice bran oil. The goal of this study was to investigate the effect of ã-oryzanol-rich extract from black rice bran (ãORE) on the activation of the innat... | ['Animals', 'Chemokine CCL2', 'Immunity, Innate', 'Interleukin-8', 'Macrophages', 'Mice', 'Oryza', 'Phenylpropionates', 'Plant Extracts', 'RAW 264.7 Cells', 'Toll-Like Receptor 4'] | 28,686,509 | [['B01.050'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['G12.450.564'], ['D12.644.276.374.200.120.800', 'D12.644.276.374.465.312', 'D12.776.467.374.200.120.800', 'D12.776.467.374.465.246', 'D23.125.300.12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrophysiological evidence for the presence of fibers in continuity between dorsal and ventral roots in the cat. | Action potentials were recorded from the L7 or S1 dorsal root of the cat following stimulation of the peripheral end of the cut ventral root of the same segment. Conversely, action potentials were also recorded from the ventral root while stimulating the peripheral end of the cut dorsal root. Based on the conduction ve... | ['Animals', 'Cats', 'Ganglia, Spinal', 'Nerve Fibers', 'Nerve Fibers, Myelinated', 'Neural Conduction', 'Neurons, Afferent', 'Reaction Time', 'Spinal Cord', 'Spinal Nerve Roots'] | 4,027,602 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['A08.675.542', 'A11.671.501'], ['A08.675.542.512', 'A11.671.501.512', 'A11.671.514'], ['G07.265.753', 'G11.561.601'], ['A08.675.650', 'A11.671.650'], ['E05.796.817', 'F02.830.650', 'F04.669... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Raising enthusiasm for the medical care of elderly patients: a concept mapping study to find elements for an elderly friendly medical curriculum. | BACKGROUND: To deliver high quality of care for the growing population of older patients more geriatricians are needed. However, the interest of medical students for a career in geriatrics is lagging behind due to a lack of exposure, the nature of the work, and the low status and financial rewards. So far, only isolate... | ['Aged', 'Attitude of Health Personnel', 'Career Choice', 'Curriculum', 'Education, Medical, Undergraduate', 'Geriatrics', 'Health Services Research', 'Humans', 'Netherlands', 'Schools, Medical', 'Students, Medical'] | 30,342,513 | [['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['F02.463.785.373.346.400'], ['I02.158'], ['I02.358.399.450'], ['H02.403.355'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.651'], ['I02.783.495.552', 'N02.278.020.578'], ['M01.848.769.602']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Expression of a novel bi-directional Brassica napus promoter in soybean. | The expression profile of a natural bi-directional promoter, derived from the Brassica napus EPSPS-A gene, was studied in transgenic soybean (Glycine max C.V. Maverick) lines. Two constructs, pDAB100331 and pDAB100333, were assembled to test the bi-directionality of the promoter. Two reporter genes, gfp and gusA, were ... | ['3-Phosphoshikimate 1-Carboxyvinyltransferase', "5' Untranslated Regions", 'Brassica napus', 'Gene Expression Regulation, Plant', 'Green Fluorescent Proteins', 'Plant Proteins', 'Plants, Genetically Modified', 'Promoter Regions, Genetic', 'Soybeans'] | 28,916,981 | [['D08.811.913.225.735'], ['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['B01.650.940.800.575.912.250.157.200.249'], ['G05.308.375'], ['D12.776.532.265'], ['D12.776.765'], ['B01.650.520', 'B05.620.600'], ['G02.111.570.080.689.675', 'G05.360.080... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Loss of androgen receptor expression predicts early recurrence in triple-negative and basal-like breast cancer. | Treatment of triple-negative invasive breast cancers, defined by the absence of estrogen and progesterone receptors and c-erbB2 expression, remains challenging. Androgen receptor, a member of the nuclear receptor superfamily that is involved in signaling pathways regulating cell proliferation, has been implicated in br... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Disease-Free Survival', 'Female', 'Humans', 'Immunohistochemistry', 'Kaplan-Meier Estimate', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prognosis', 'Proportional Hazards Models', 'Receptors, Androgen', 'Tissue Array Analysis', 'Triple Negative Breast Neopl... | 23,929,266 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Outcomes of Direct-Acting Antiviral Treatment of Psychiatric Patients with Comorbid Hepatitis C Virus Infection. | BACKGROUND: The highest burden of hepatitis C virus (HCV) infection is seen in patients with psychiatric disorders who have been excluded from traditional treatments with Interferon due to treatment-emergent neuropsychiatric adverse effects. The goal of this study is to determine the tolerability, treatment retention, ... | ['Antiviral Agents', 'Comorbidity', 'Female', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Retrospective Studies', 'Substance-Related Disorders', 'Sustained Virologic Response', 'Treatment Outcome'] | 31,494,648 | [['D27.505.954.122.388'], ['N05.715.350.225', 'N06.850.490.687'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['E05.318.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Smoking, alcohol and caffeine consumption of mothers before, during and after pregnancy--results of the study 'breast-feeding habits in Bavaria']. | AIM OF THE STUDY: The aim of this analysis of the study 'Breast-feeding habits in Bavaria' is to describe the smoking habits, alcohol and caffeine consumption of mothers in Bavaria before, during and after pregnancy. Furthermore, we asked about the environmental tabacco smoke exposition of pregnant women and infants. T... | ['Adult', 'Alcohol Drinking', 'Breast Feeding', 'Caffeine', 'Cohort Studies', 'Comorbidity', 'Female', 'Germany', 'Humans', 'Middle Aged', 'Mothers', 'Pregnancy', 'Prevalence', 'Smoking', 'Young Adult'] | 19,326,332 | [['M01.060.116'], ['F01.145.317.269'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['Z01.542.315'], ['B... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Plasmoredoxin, a novel redox-active protein unique for malarial parasites. | Thioredoxins are a group of small redox-active proteins involved in cellular redox regulatory processes as well as antioxidant defense. Thioredoxin, glutaredoxin, and tryparedoxin are members of the thioredoxin superfamily and share structural and functional characteristics. In the malarial parasite, Plasmodium falcipa... | ['Amino Acid Sequence', 'Animals', 'Disulfides', 'Glutathione Disulfide', 'Insulin', 'Molecular Sequence Data', 'Multigene Family', 'Oxidation-Reduction', 'Phylogeny', 'Plasmodium falciparum', 'Protozoan Proteins', 'Sequence Alignment', 'Thioredoxins'] | 12,631,266 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['D12.644.456.448.500'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['G02.700', 'G03.295.531'], ['G05.697', 'G16.075.605... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Practitioner facing depression (author's transl)]. | The author underlines how important it is not to neglect an organical illness, particularly if the patient is of age since it is easy to diagnosticate a depression. He enumarates the various complementary examinations which, combined to a clinical one would allow to reject an organical cause. | ['Alcoholism', 'Cerebrovascular Disorders', 'Coronary Disease', 'Depressive Disorder', 'Diabetes Complications', 'Humans', 'Nervous System Diseases', 'Time Factors'] | 7,318,768 | [['C25.775.100.250', 'F03.900.100.350'], ['C10.228.140.300', 'C14.907.253'], ['C14.280.647.250', 'C14.907.585.250'], ['F03.600.300'], ['C19.246.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10'], ['G01.910.857']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Feasibility of unilateral or bilateral nerve-sparing radical hysterectomy in patients with cervical cancer and evaluation of the post-surgery recovery of the bladder and rectal function]. | OBJECTIVE: To investigate the feasibility of unilateral or bilateral nerve-sparing radical hysterectomy and evaluate the recovery of bladder and bowel function postoperatively.METHODS: From August 2008 to October 2009, sixty-one patients with cervical cancer stage Ib1 to IIa underwent radical hysterectomy (33 cases) an... | ['Adult', 'Aged', 'Blood Loss, Surgical', 'Carcinoma, Squamous Cell', 'Female', 'Follow-Up Studies', 'Humans', 'Hysterectomy', 'Length of Stay', 'Middle Aged', 'Neoplasm Staging', 'Pelvis', 'Postoperative Complications', 'Postoperative Period', 'Rectum', 'Urinary Bladder', 'Urination', 'Urination Disorders', 'Uterine C... | 21,575,466 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.414.300', 'C23.550.505.300'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E02.760.400.480', 'N02.421.585... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Orbital bone changes in neurofibromatosis. Tomodensitometric diagnosis]. | Aplasia of the greater wing of the sphenoid is a characteristic orbital bony anomaly in von Recklinghausen's disease, responsible for unilateral proptosis. The radiological diagnosis is based on the so called "empty orbit" appearance at routine skull X rays. Computerised tomography has allowed a precise differential di... | ['Adolescent', 'Adult', 'Brain Diseases', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Hyperplasia', 'Male', 'Neurofibromatosis 1', 'Orbital Neoplasms', 'Skull', 'Tomography, X-Ray Computed'] | 6,810,414 | [['M01.060.057'], ['M01.060.116'], ['C10.228.140'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['C04.557.580.600.580.590.650', 'C04.700.631.650', 'C10.562.600.500', 'C10.574.500.549.400', 'C10.668.829.675', 'C16.320.400.560.400', 'C16.320.700.633.650'], ['C04... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Functional paralysis of horizontal gaze. | A 52-year-old steelworker displayed a consistent defect in leftward voluntary gaze across the midline. Both fast (saccadic) and slow (pursuit) eye movements were affected. Neuro-ophthalmologic evaluation revealed no additional neurologic or ophthalmologic deficit. Pupilary miosis occurred during leftward gaze attempt, ... | ['Eye Movements', 'Fixation, Ocular', 'Humans', 'Male', 'Middle Aged', 'Ophthalmoplegia', 'Saccades', 'Visual Fields'] | 570,680 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Automatic classification of background EEG activity in healthy and sick neonates. | The overall aim of our research is to develop methods for a monitoring system to be used at neonatal intensive care units. When monitoring a baby, a range of different types of background activity needs to be considered. In this work, we have developed a scheme for automatic classification of background EEG activity in... | ['Asphyxia Neonatorum', 'Automation', 'Brain', 'Discriminant Analysis', 'Electroencephalography', 'Humans', 'Infant, Newborn', 'Linear Models', 'Monitoring, Physiologic', 'Motor Activity', 'Probability', 'Signal Processing, Computer-Assisted', 'Sleep', 'Time Factors', 'Wakefulness'] | 20,075,506 | [['C16.614.092'], ['J01.897.104'], ['A08.186.211'], ['E05.318.740.350', 'N05.715.360.750.325', 'N06.850.520.830.350'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460'... | ['Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Relationship between CHA2DS2-VASc and CHADS2 scores with pulmonary hypertension in patients with acute pulmonary embolism. | INTRODUCTION: Pulmonary hypertension (PH) is the most important prognostic factor after acute pulmonary embolism (PE). Therefore, determination of patients who will develop PH after acute PE is crucial. The aim of the present study was to evaluate the predictive value of the CHADS2 and CHA2DS2-VASc scores for PH in pat... | ['Adult', 'Female', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Middle Aged', 'Pulmonary Artery', 'Pulmonary Embolism', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Severity of Illness Index'] | 31,970,721 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.116.630'], ['A07.015.114.715'], ['C08.381.746', 'C14.907.355.350.700'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.5... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional neurosurgery--a future for the gamma knife? | The Gamma Knife is currently the only radiosurgical device which has been used in functional neurosurgery. This mode of utilization is possible because the instrument can make lesions in normal brains with a volume as small as 50 mm3. The experience of functional radiosurgery accumulated at the Karolinska Institute ove... | ['Adult', 'Brain', 'Epilepsy', 'Follow-Up Studies', 'Forecasting', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Movement Disorders', 'Neurosurgery', 'Palliative Care', 'Psychosurgery', 'Radiosurgery'] | 1,725,560 | [['M01.060.116'], ['A08.186.211'], ['C10.228.140.490'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C10.228.662'], ['H02.403.810.425'], ['E02.760.666', 'N02.421.585.666'], ['E04.525.60... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[The use of microcrystalline cellulose dispersions for the production of dermatologic agents]. | The employment oft microcrystalline cellulose of the Heweten-type (cellulose powder(AB-GDR) for the production of dermatological preparations as aqueous and aqueous-oily multicomponent systems can contribute to the opening of a further field of application of this auxiliary substance in pharmaceutical factories and pha... | ['Cellulose', 'Chemistry, Pharmaceutical', 'Dermatologic Agents', 'Emulsions'] | 3,786,383 | [['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['H01.158.703.007', 'H01.181.466'], ['D27.505.954.444'], ['D20.280.260', 'D26.255.165.260']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Artemisinin sensitizes tumor cells to NK cell-mediated cytolysis. | The antimalarial drug Artemisinin has been reported to possess direct anti-tumor effects on various types of tumor cells. However, its anti-tumor potential has not been fully revealed, and its effects on tumor susceptibility to immune surveillance by the host are still unknown. Natural killer (NK) cells are the first l... | ['Animals', 'Antimalarials', 'Antineoplastic Agents', 'Artemisinins', 'Cell Line, Tumor', 'Cells, Cultured', 'Cytotoxicity, Immunologic', 'Humans', 'Immunologic Surveillance', 'Killer Cells, Natural', 'Mice', 'Neoplasms'] | 32,007,276 | [['B01.050'], ['D27.505.954.122.250.100.085'], ['D27.505.954.248'], ['D01.248.497.158.685.750.212', 'D01.339.431.374.212', 'D01.650.550.750.200', 'D02.389.338.055', 'D02.455.849.765.211'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.251'], ['G12.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.40... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photodynamic therapy mediated by methylene blue dye in wound healing. | OBJECTIVE: We sought to investigate the wound-healing process after photodynamic therapy (PDT) mediated by methylene blue dye (MB).BACKGROUND DATA: Few scientific studies show the PDT roles in wound healing.MATERIALS AND METHODS: One hundred rats were given a circular wound on the back, inflicted with a 6-mm-diameter p... | ['Animals', 'Biopsy, Needle', 'Coloring Agents', 'Disease Models, Animal', 'Female', 'Immunohistochemistry', 'Low-Level Light Therapy', 'Methylene Blue', 'Photochemotherapy', 'Random Allocation', 'Rats', 'Rats, Wistar', 'Statistics, Nonparametric', 'Wound Healing', 'Wounds and Injuries'] | 20,961,226 | [['B01.050'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['D27.720.233'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', '... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Immune profile of infectious bursal disease (IBD). II. Effect of IBD virus on pokeweed-mitogen-stimulated peripheral blood lymphocytes of chickens. | Pokeweed-mitogen-stimulated peripheral blood lymphocytes from chickens infected with infectious bursal disease virus (IBDV) at 1 day and 3 weeks of age, together with those from uninfected age-matched control chickens, were examined at weekly intervals for their capacity to undergo in vitro terminal differentiation. Th... | ['Animals', 'Antibody-Producing Cells', 'B-Lymphocytes', 'Cell Membrane', 'Chickens', 'Cytoplasm', 'Fluorescent Antibody Technique', 'Immunoglobulin G', 'Infectious bursal disease virus', 'Lymphocyte Activation', 'Pokeweed Mitogens', 'Poultry Diseases', 'Reoviridae', 'Reoviridae Infections'] | 6,255,927 | [['B01.050'], ['A11.063', 'A15.382.032'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.284.149'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.284.430.214'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.51... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical location of S-100 and glial fibrillary acidic proteins in salivary gland pleomorphic adenomas. | The S-100 protein is a low molecular weight protein which has been isolated mainly in mammalian brain cells. Glial fibrillary acidic protein is one of the five types of intermediate filaments described to date. We used immunohistochemical methods to study the expression in this patterns of expression of these two prote... | ['Adenoma, Pleomorphic', 'Glial Fibrillary Acidic Protein', 'Humans', 'Immunohistochemistry', 'S100 Proteins', 'Salivary Gland Neoplasms'] | 2,168,578 | [['C04.557.435.090', 'C04.557.470.035.155'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytoskeleton involvement in lithium-induced SH-SY5Y neuritogenesis and the role of glycogen synthase kinase 3â. | Lithium modulates signals impacting on the cytoskeleton, a dynamic system contributing to neural plasticity at multiple levels. In this study, SH-SY5Y human neuronal cells were cultured in the absence (C) or in presence (Li) of a 0.5 mM Li2CO3 (i.e. 1 mM lithium ion) for 25-50 weeks. We investigated the effect of this ... | ['Cells, Cultured', 'Cytoskeleton', 'Glycogen Synthase', 'Glycogen Synthase Kinase 3', 'Glycogen Synthase Kinase 3 beta', 'Humans', 'Lithium Compounds', 'Nerve Degeneration', 'Neurites', 'Neurogenesis', 'Neuronal Plasticity', 'Neuroprotective Agents', 'Treatment Outcome'] | 25,409,859 | [['A11.251'], ['A11.284.430.214.190.750'], ['D08.811.913.400.450.460.375'], ['D05.500.117.875', 'D08.811.913.696.620.682.700.429.500', 'D08.811.913.696.620.682.700.646.625', 'D12.644.360.300.500', 'D12.776.476.081.875', 'D12.776.476.300.500'], ['D05.500.117.875.500', 'D08.811.913.696.620.682.700.429.500.500', 'D08.811.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Connexin-43 enhances tumor suppressing activity of artesunate via gap junction-dependent as well as independent pathways in human breast cancer cells. | The gap junction (GJ) protein connexin-43 (Cx43) is considered as a tumour suppressor protein for its role in reversing the phenotype of the cancer cells. In this study, we exploited the antitumor property of Cx43 in conjunction with the artesunate (ART), a plant-based active anti-malarial compound. The reactive oxygen... | ['Antineoplastic Agents', 'Artesunate', 'Breast Neoplasms', 'Cell Survival', 'Connexin 43', 'DNA Damage', 'Gap Junctions', 'Humans', 'Inhibitory Concentration 50', 'MCF-7 Cells', 'Models, Biological', 'Reactive Oxygen Species'] | 28,790,385 | [['D27.505.954.248'], ['D01.248.497.158.685.750.212.500', 'D01.339.431.374.212.500', 'D01.650.550.750.200.500', 'D02.389.338.055.500', 'D02.455.849.765.211.500'], ['C04.588.180', 'C17.800.090.500'], ['G04.346'], ['D12.776.543.585.250.200'], ['G05.200'], ['A11.284.149.165.420.471'], ['B01.050.150.900.649.313.988.400.112... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dynamics of PhiX174 protein E-mediated lysis of Escherichia coli. | Expression of cloned gene E of bacteriophage PhiX174 induces lysis by formation of a transmembrane tunnel structure in the cell envelope of Escherichia coli. Ultrastructural studies of the location of the lysis tunnel indicate that it is preferentially located at the septum or at polar regions of the cell. Furthermore,... | ['Adenosine Triphosphatases', 'Bacteriolysis', 'Cell Membrane', 'Escherichia coli', 'Microscopy, Electron', 'Osmotic Pressure', 'Viral Proteins'] | 1,534,215 | [['D08.811.277.040.025'], ['G06.099.115'], ['A11.284.149'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E01.370.350.515.402', 'E05.595.402'], ['G01.374.715.578', 'G02.640.249', 'G02.723.661'], ['D12.776.964']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Statistical dependence between neighboring retinal ganglion cells in goldfish. | Simultaneous recordings were made of the spontaneous discharge of neighboring retinal ganglion cells in goldfish. Crosscorrelation analysis indicates two types of correlation. Neighboring units with like receptive field organization tend to discharge together while units having complementary receptive field organizatio... | ['Action Potentials', 'Animals', 'Color Perception', 'Cyprinidae', 'Goldfish', 'Models, Neurological', 'Neurons', 'Photic Stimulation', 'Photoreceptor Cells', 'Retina'] | 658,187 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['F02.463.593.932.217'], ['B01.050.150.900.493.200.244'], ['B01.050.150.900.493.200.244.248.480'], ['E05.599.395.642'], ['A08.675', 'A11.671'], ['E05.723.729'], ['A08.675.650.850.625', 'A08.675.650.915.937', 'A08.800.950.937', 'A09.371.729.831.625', '... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of vitamin A status in children treated for cancer. | Chemotherapy for cancer can cause immunocompromise. The authors speculated that children with cancer and low vitamin A plasma levels were more susceptible to cancer treatment-related complications than children who are not vitamin A deficient. A cohort of 49 children with cancer were followed from diagnosis until death... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Neoplasms', 'Neutropenia', 'Survival Rate', 'Vitamin A', 'Vitamin A Deficiency'] | 18,484,472 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04'], ['C15.378.553.546.184.564'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505.400.975.550.900', 'N06.850.520.308.985.550.900'], ['D02.455.326.271.665.202.495.818', 'D02.455.4... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hepatocarcinogenic effects of N-nitroso-N-methylurea in guinea pigs. | Intragastric administration of N-nitroso-N-methylurea to strain 13 male guinea pigs, at a weekly dosage of 7.5 mg/kg for 15 weeks and then twice weekly for a subsequent 15 weeks, induced high toxicity, as evidenced by weight loss and mortality and a high incidence of malignant neoplasms, over a total observational peri... | ['Adenoma, Bile Duct', 'Animals', 'Chemical and Drug Induced Liver Injury', 'Guinea Pigs', 'Hemangiosarcoma', 'Liver Diseases', 'Liver Neoplasms', 'Male', 'Methylnitrosourea', 'Neoplasms, Experimental', 'Nitrosourea Compounds'] | 198,127 | [['C04.557.470.035.085'], ['B01.050'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['B01.050.150.900.649.313.992.550'], ['C04.557.450.795.390', 'C04.557.645.390'], ['C06.552'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['D02.065.950.594.490', 'D02.654.692.480'], ['C04.619', 'E05.598.500.496'], ['D02.065.950... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Respiratory influences on the cardiac defense response. | An investigation to examine the relationships between breathing activity and the cardiac defense response (CDR) to intense auditory stimulation is reported. 42 subjects (20 men and 22 women) underwent a physiological reaction test consisting of three trials of a distorted 400 Hz noise of 100 dB, 0.5-s duration and inst... | ['Acoustic Stimulation', 'Adolescent', 'Adult', 'Female', 'Heart', 'Humans', 'Lung Volume Measurements', 'Male', 'Reflex', 'Respiratory Function Tests', 'Respiratory Mechanics', 'Sex Characteristics'] | 8,407,430 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.057'], ['M01.060.116'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.485'], ['E01.370.376.550.650', 'E01.370.600.550.650', 'F02.830.702', 'G11.561.731'], ['E01.370.386.700'], ['G09.772.705.700'], ['G08.686.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mechanisms and regulation of H+ transport in distal tubule epithelial cells. | The mechanism of acidification in the cortical distal tubule of mammalian kidney was analysed by "in vivo" microperfusion and using MDCK cells in culture, by electrophysiological and by cell pH microfluorescence techniques. An electrogenic effect of the vacuolar H(+)-ATPase, which has been localized to the intercalated... | ['Acid-Base Equilibrium', 'Angiotensin I', 'Animals', 'Calcium', 'Cell Line', 'Chloride Channels', 'Epithelial Cells', 'Epithelium', 'Kidney Tubules, Distal', 'Male', 'Proton-Translocating ATPases', 'Rats', 'Rats, Wistar', 'Sodium', 'Vasopressins'] | 9,261,982 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['D06.472.699.094.075', 'D12.644.400.070.075', 'D12.644.456.073.021', 'D12.644.548.058.075', 'D12.776.631.650.070.075', 'D23.469.050.050.025'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['D12.776.157.530... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Echocardiographic features of patients with paroxysmal atrial fibrillation. | BACKGROUND: There are several risk factors for the initiation of paroxysmal atrial fibrillation (PAF) and the underlying mechanisms are multifactorial. Our study aims to explore the echocardiographic parameters that can identify in patients with PAF compared to normal subjects.METHODS: Eighty consecutive patients who w... | ['Atrial Fibrillation', 'Case-Control Studies', 'Chi-Square Distribution', 'Echocardiography, Doppler', 'Electrocardiography, Ambulatory', 'Female', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Risk Factors'] | 17,597,421 | [['C14.280.067.198', 'C23.550.073.198'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increased blood pressure variability in menopause. | Blood pressure variability represents an independent risk factor for cardiovascular diseases. To detect possible blood pressure variability changes from fertile to menopausal status, we enrolled consecutively 219 women: 104 fertile women (46.6 +/- 3.4 years) and 115 menopausal women (53.9 +/- 3.98 years). We evaluated ... | ['Adult', 'Age Factors', 'Aging', 'Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'Body Mass Index', 'Case-Control Studies', 'Circadian Rhythm', 'Female', 'Humans', 'Logistic Models', 'Menopause', 'Middle Aged', 'Multivariate Analysis', 'Prospective Studies'] | 18,575,158 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['G07.345.124'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Inguinal hernia and testicular feminization in childhood (author's transl)]. | Three cases of Morris Syndrome were detected among 103 girls admitted to the hospital for inguinal hernia. Diagnosis was made possible by routine sexual chromatine study in oral mucosa smear, but it can also be suspected when familial antecedents of amenorrhea exist. An early diagnosis of this condition is imperative i... | ['Androgen-Insensitivity Syndrome', 'Child, Preschool', 'Diagnosis, Differential', 'Hernia, Inguinal', 'Humans', 'Infant', 'Male', 'Mouth Mucosa', 'Phenotype', 'Saliva', 'Sex Chromatin'] | 507,576 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sealing ability of thermoplasticized gutta-percha fill techniques as assessed by a new method of determining apical leakage. | One hundred fifty-nine extracted single-rooted maxillary human teeth were instrumented and randomly divided into nine groups of 17 teeth each and 6 control teeth. Experimental groups were obturated with Thermafil, Obtura II, Ultrafil Regular Set gutta-percha, and Ultrafil Firm Set gutta-percha, each with or without roo... | ['Chi-Square Distribution', 'Dental Leakage', 'Dental Marginal Adaptation', 'Formaldehyde', 'Gutta-Percha', 'Hot Temperature', 'Humans', 'Maxilla', 'Resins, Synthetic', 'Resorcinols', 'Root Canal Filling Materials', 'Root Canal Obturation'] | 7,673,814 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C07.793.221'], ['E06.323.764', 'E06.658.224', 'E06.780.620'], ['D02.047.407'], ['D20.215.721.061', 'D25.339.859.495', 'D25.720.327.840.119', 'J01.637.051.339.859.495'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Intracellular pathways of electron-opaque gonadotropin-releasing hormone derivatives bound by cultured gonadotropes. | A metabolically stable GnRH agonist (D-Lys6-GnRH) has been coupled to electron-opaque markers (colloidal gold and ferritin) to characterize the intracellular pathway of the releasing hormone bound by pituitary gonadotropes. This approach has the advantage of increasing the resolution of localization to a "circle of unc... | ['Animals', 'Cells, Cultured', 'Female', 'Ferritins', 'Gold Colloid, Radioactive', 'Gonadotropin-Releasing Hormone', 'Microscopy, Electron', 'Pituitary Gland', 'Rats', 'Receptors, Cell Surface', 'Receptors, LHRH'] | 6,313,329 | [['B01.050'], ['A11.251'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['D01.268.556.322.500.550.400', 'D01.268.956.186.500.550.400', 'D01.379.400.350', 'D01.496.381.550.400', 'D01.496.749.410.400', 'D01.552.544.322.500.550.400'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.54... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structural basis for regulation of Arp2/3 complex by GMF. | The Arp2/3 complex mediates formation of complex cellular structures such as lamellipodia by nucleating branched actin filaments. Arp2/3-complex activity is precisely controlled by over a dozen regulators, yet the structural mechanism by which regulators interact with the complex is unknown. GMF is a recently discovere... | ['Actin-Related Protein 2-3 Complex', 'Actins', 'Amino Acid Sequence', 'Animals', 'Cattle', 'Crystallography, X-Ray', 'Glia Maturation Factor', 'Mice', 'Models, Molecular', 'Molecular Sequence Data', 'Multiprotein Complexes', 'Protein Interaction Domains and Motifs', 'Protein Subunits', 'Recombinant Proteins', 'Sequenc... | 23,893,131 | [['D05.750.078.730.246', 'D12.776.220.525.246'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.309.742.225'], ['D12.644.276.860.325', 'D12.776.467.860.325', 'D12.776.631.600.325', 'D23.52... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The Hen's Egg Test on Chorioallantoic Membrane: An Alternative Assay for the Assessment of the Irritating Effect of Vaccine Adjuvants. | Local reactions are the most frequent adverse event associated with vaccines. Adjuvants are major constituents of many vaccines and they are frequently involved in these reactions, associated with their irritating effect and the stimulation of local inflammation. The hen's egg test on chorioallantoic membrane (HET-CAM)... | ['Adjuvants, Immunologic', 'Animal Testing Alternatives', 'Animals', 'Biological Assay', 'Chickens', 'Chorioallantoic Membrane', 'Female', 'Irritants', 'Mice, Inbred BALB C', 'Skin', 'Vaccines'] | 27,733,445 | [['D27.505.696.477.067'], ['E05.017.080.100'], ['B01.050'], ['E05.091'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A10.615.284.375', 'A13.350.575', 'A16.331.400'], ['D27.720.400', 'D27.888.569.300'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['A17.815'],... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of the core exon-junction complex factor eukaryotic initiation factor 4A3 is increased during spatial exploration and striatally-mediated learning. | Regulation of dendritically localized mRNAs offers an important means by which neurons can sculpt precise signals at synapses. Arc is one such dendritically localized mRNA, and it has been shown to contain two exon-junction complexes (EJCs) within its 3'UTR. The EJC has been postulated to regulate cytoplasmic Arc mRNA ... | ['Animals', 'Cytoskeletal Proteins', 'DEAD-box RNA Helicases', 'Exons', 'Exploratory Behavior', 'Hippocampus', 'Image Processing, Computer-Assisted', 'Immunohistochemistry', 'In Situ Hybridization', 'Learning', 'Male', 'Maze Learning', 'Neostriatum', 'Nerve Tissue Proteins', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Daw... | 22,982,623 | [['B01.050'], ['D12.776.220'], ['D08.811.913.696.445.735.720.249'], ['G05.360.340.024.340.137.232'], ['F01.145.387', 'F01.658.370'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['L01.224.308'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Association of S100B Serum Levels with Metabolic Syndrome and its Components. | INTRODUCTION: We aimed to compare serum levels of S100B between patients with metabolic syndrome and healthy subjects and to investigate the association of S100B with components of the metabolic syndrome.MATERIALS AND METHODS: In this study, 44 patients with metabolic syndrome and 44 healthy subjects participated. The ... | ['Adult', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'S100 Calcium Binding Protein beta Subunit'] | 29,855,413 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500.570', 'C18.452.625'], ['M01.060.116.630'], ['D12.776.157.125.750.625', 'D12.776.631.655.750']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High level of serum apolipoprotein A-I is a favorable prognostic factor for overall survival in esophageal squamous cell carcinoma. | BACKGROUND: Noninvasive prognostic tools for esophageal squamous cell carcinoma (ESCC) are urgently needed. Serum lipids and lipoproteins are used for the prognosis of certain diseases; however, the prognostic value of serum apolipoprotein A-I (ApoA-I) in ESCC has not been described.METHODS: Pre-treatment serum lipids ... | ['Adult', 'Aged', 'Apolipoprotein A-I', 'Biomarkers, Tumor', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Esophageal Squamous Cell Carcinoma', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Prognosis', 'Proportional Hazards Models'] | 27,444,612 | [['M01.060.116'], ['M01.060.116.100'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['D23.101.140'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['C04.557.470.200.400.330', 'C04.557... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Epiphyseal distraction for bony bridges: a biomechanical and morphologic study. | Partial physeal bridges were produced by resecting part of the lower femoral physis in 8-week-old rabbits. After 4 weeks, an external fixator, strain-gauged to measure distraction forces, was applied across the physis. Distraction was performed for 15 days: 1.0 mm/day medially and 0.5 mm/day laterally. Weekly radiograp... | ['Animals', 'Biomechanical Phenomena', 'External Fixators', 'Femur', 'Joint Deformities, Acquired', 'Knee Joint', 'Male', 'Rabbits', 'Radiography', 'Synostosis'] | 8,416,353 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['A02.835.232.043.150'], ['C05.550.515'], ['A02.835.583.475'], ['B01.050.150.900.649.313.968.700'], ['E01.370.350.700'], ['C05.116.099.370.894', 'C05.660.906', 'C16.131.621.906']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Agrobacterium tumefaciens VirB7 and VirB9 form a disulfide-linked protein complex. | Agrobacterium tumefaciens VirB proteins are essential for gene transfer from bacteria to plants. These proteins are postulated to form a transport pore to allow transfer of the T-strand DNA intermediate. To study the function of the VirB proteins in DNA transfer, we developed an expression system in A. tumefaciens. Ana... | ['Agrobacterium tumefaciens', 'Bacterial Proteins', 'Cysteine', 'DNA Mutational Analysis', 'Disulfides', 'Electrophoresis, Polyacrylamide Gel', 'Genes, Bacterial', 'Mutagenesis, Site-Directed', 'Protein Binding', 'Protein Conformation', 'Recombinant Proteins', 'Virulence Factors'] | 8,799,123 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['D12.776.097'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['E05.393.760.700.300'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.360.340.024.340.364.24... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metal on metal surface replacement of the hip. Technique, fixation, and early results. | High volumetric wear of polyethylene plays a central role in periprosthetic bone resorption and the failure of metal on polyethylene total hip resurfacing prostheses. An assessment of technique, initial fixation, and the early results of 21 hips in 19 patients implanted with a metal on metal bearing total hip resurfaci... | ['Adult', 'Female', 'Follow-Up Studies', 'Hip Prosthesis', 'Humans', 'Male', 'Metals', 'Middle Aged', 'Osseointegration', 'Pilot Projects', 'Prospective Studies', 'Prosthesis Design', 'Prosthesis Fitting'] | 8,769,328 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.552'], ['M01.060.116.630'], ['G11.427.213.140.570', 'G16.762.150.150.570'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Subclinical prion disease induced by oral inoculation. | Natural transmission of prion disease is believed to occur by peripheral infection such as oral inoculation. Following this route of inoculation, both the peripheral nervous system and the lymphoreticular system may be involved in the subsequent neuroinvasion of the central nervous system by prions, which may not neces... | ['Administration, Oral', 'Animals', 'Brain', 'Immunohistochemistry', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'PrPC Proteins', 'PrPSc Proteins', 'Prion Diseases', 'Prions', 'Spleen'] | 12,829,838 | [['E02.319.267.100'], ['B01.050'], ['A08.186.211'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['B01.050.150.900.649.313.992.63... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term reduction of T-cell intracellular antigens leads to increased beta-actin expression. | BACKGROUND: The permanent down-regulated expression of T-cell intracellular antigen (TIA) proteins in HeLa cells improves cytoskeleton-mediated functions such as cell proliferation and tumor growth.METHODS: Making use of human and mouse cells with knocked down/out expression of T-cell intracellular antigen 1 (TIA1) and... | ["3' Untranslated Regions", 'Actins', 'Animals', 'Base Sequence', 'Fibroblasts', 'Gene Expression Regulation', 'Genes, Reporter', 'Green Fluorescent Proteins', 'HeLa Cells', 'Humans', 'Mice', 'Molecular Sequence Data', 'Poly(A)-Binding Proteins', 'RNA-Binding Proteins', 'Signal Transduction', 'T-Cell Intracellular Anti... | 24,766,723 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.329.228'], ['G05.308'], ['G05.360.340.024.340.43... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Integration of ultrasonography and endoscopy into transsphenoidal surgery with a "picture-in-picture" viewing system--technical note. | A technique to integrate ultrasonography and endoscopy is described for transsphenoidal surgery to prevent intraoperative internal carotid artery (ICA)-related, life-threatening complications such as aneurysmal formation and carotid-cavernous fistula. The ultrasound unit helps avoid direct injury to the ICA. The techni... | ['Carotid Artery Injuries', 'Carotid Artery, Internal', 'Cavernous Sinus', 'Computer Systems', 'Data Display', 'Endoscopes', 'Endoscopy', 'Equipment Design', 'Humans', 'Hypophysectomy', 'Intraoperative Care', 'Intraoperative Complications', 'Microsurgery', 'Ultrasonography, Doppler', 'Ultrasonography, Interventional', ... | 12,116,536 | [['C10.228.140.300.200.345', 'C10.228.140.300.350.500', 'C10.900.250.300', 'C14.907.253.123.345', 'C14.907.253.535.500', 'C26.915.200.200'], ['A07.015.114.186.200.230'], ['A07.015.908.224.334'], ['L01.224.230'], ['F02.784.412.221', 'L01.296'], ['E07.230.220', 'E07.858.240'], ['E01.370.388.250', 'E04.502.250'], ['E05.32... | ['Diseases [C]', 'Anatomy [A]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Modulation by progestogens of the effects of oestrogen on hepatic endocrine function in postmenopausal women. | OBJECTIVE: Oral but not transdermal oestrogen administration reduces IGF-I, and increases GH binding protein (GHBP) reflecting effects on hepatic endocrine function in postmenopausal women. As progestogens attenuate the effects of oestrogen on circulating lipid levels according to their androgenic properties, we have i... | ['Analysis of Variance', 'Carrier Proteins', 'Cyproterone Acetate', 'Dydrogesterone', 'Estradiol', 'Estrogen Replacement Therapy', 'Estrogens, Conjugated (USP)', 'Female', 'Humans', 'Insulin-Like Growth Factor I', 'Lipids', 'Liver', 'Medroxyprogesterone Acetate', 'Middle Aged', 'Norethindrone', 'Postmenopause', 'Proges... | 14,974,909 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D12.776.157'], ['D04.210.500.745.432.219.150', 'D04.210.500.883.419.150'], ['D04.210.500.745.432.296'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E02.319.452.150'], ['D06.472.334.851.437.988'], ['B01.050.150.900.649.313.988.400.112.40... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ubiquitin-independent proteasomal degradation of endoplasmic reticulum-localized connexin43 mediated by CIP75. | Connexin43 (Cx43) is a transmembrane protein that forms gap junction channels. Regulation of Cx43 turnover is one mechanism to control the level of intercellular communication that occurs through gap junction channels. Proteasomal degradation of Cx43 is regulated in part through CIP75, a ubiquitin-like and ubiquitin-as... | ['Amino Acid Substitution', 'Animals', 'Autophagy-Related Proteins', 'Carrier Proteins', 'Connexin 43', 'Endoplasmic Reticulum', 'HeLa Cells', 'Humans', 'Mice', 'Mutation, Missense', 'Nuclear Proteins', 'Proteasome Endopeptidase Complex', 'Protein Binding', 'Ubiquitin', 'Ubiquitination'] | 20,940,304 | [['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['D12.776.094'], ['D12.776.157'], ['D12.776.543.585.250.200'], ['A11.284.430.214.190.875.248'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.590... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status. | Glioblastomas epidemiology and aggressiveness demand for a well characterization of biochemical mechanisms of the cells. The discovery of oxidative tumours related to chemoresistance is changing the prevalent view of dysfunctional mitochondria in cancer cells. Thus, glioblastomas metabolism is now an area of intense re... | ['Cell Line, Tumor', 'Energy Metabolism', 'Glioblastoma', 'Humans', 'Mitochondria', 'Mutation', 'Oxidative Phosphorylation', 'PTEN Phosphohydrolase', 'Proton-Motive Force', 'Reactive Oxygen Species', 'Signal Transduction'] | 29,209,894 | [['A11.251.210.190', 'A11.251.860.180'], ['G03.295'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.080.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G05.365.590'], ['G02.111.665.550', 'G03.295.631', 'G03.796.5... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Shoot surface water uptake enables leaf hydraulic recovery in Avicennia marina. | The significance of shoot surface water uptake (SSWU) has been debated, and it would depend on the range of conditions under which it occurs. We hypothesized that the decline of leaf hydraulic conductance (Kleaf ) in response to dehydration may be recovered through SSWU, and that the hydraulic conductance to SSWU (Ksur... | ['Avicennia', 'Dehydration', 'Kinetics', 'Plant Leaves', 'Plant Shoots'] | 31,419,324 | [['B01.650.940.800.575.912.250.583.040.522'], ['C18.452.950.179', 'C23.550.274'], ['G01.374.661', 'G02.111.490'], ['A18.024.812'], ['A18.024.875']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predicting negligence in female sterilization failure using time interval to sterilization failure: analysis of 131 cases. | BACKGROUND: Sterilization failure due to 'tubal non-occlusion' or 'wrong structure sterilization' is considered negligent, whereas 'spontaneous tubal recanalization' or 'fistula formation' is considered non-negligent. We examined whether interval to pregnancy failure was predictive of a negligent rather non-negligent f... | ['Adult', 'Female', 'Humans', 'Malpractice', 'Pregnancy', 'Probability', 'Proportional Hazards Models', 'Sterilization, Tubal', 'Time Factors'] | 17,599,943 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.583.524', 'N03.706.535.606'], ['G08.686.784.769'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.825', 'E05.599.835.900'... | ['Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
TGF-â1 enhances phagocytic removal of neuron debris and neuronal survival by olfactory ensheathing cells via integrin/MFG-E8 signaling pathway. | Olfactory ensheathing cells (OECs) have been shown to be a leading candidate in cell therapies for central nervous system (CNS) injuries and neurodegenerative diseases. Rapid clearance of neuron debris can promote neuronal survival and axonal regeneration in CNS injuries and neurodegenerative diseases. The phagocytic r... | ['Animals', 'Antigens, Surface', 'Cell Survival', 'Cells, Cultured', 'Integrins', 'Milk Proteins', 'Neuroglia', 'Neurons', 'Olfactory Bulb', 'Phagocytosis', 'Rats', 'Rats, Long-Evans', 'Signal Transduction', 'Transforming Growth Factor beta1'] | 28,860,093 | [['B01.050'], ['D23.050.301'], ['G04.346'], ['A11.251'], ['D12.776.543.750.705.408'], ['A12.790.520', 'D12.776.256.159.750', 'G07.203.300.428.159.812', 'J02.500.350.525.520', 'J02.500.428.159.750'], ['A08.637', 'A11.650'], ['A08.675', 'A11.671'], ['A08.186.211.200.885.388'], ['G04.417.350', 'G09.188.665', 'G12.450.564.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Clinical relevance of kallikrein-related peptidase 6 (KLK6) and 8 (KLK8) mRNA expression in advanced serous ovarian cancer. | Most members of the kallikrein-related peptidase family have been demonstrated to be dysregulated in ovarian cancer and modulate tumor growth, migration, invasion, and resistance to chemotherapy. In the present study, we assessed the mRNA expression levels of KLK6 and KLK8 by quantitative PCR in 100 patients with advan... | ['Adult', 'Aged', 'Aged, 80 and over', 'Disease-Free Survival', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Kallikreins', 'Middle Aged', 'Multivariate Analysis', 'Ovarian Neoplasms', 'RNA, Messenger', 'Young Adult'] | 27,483,364 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.442', 'D... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tracheal bronchus associated with recurrent pneumonia. | Abnormalities of the major airways are very uncommon congenital conditions which occur in approximately 2% of the adult population. Usually aberrant bronchi are asymptomatic and are only found by coincidence. We present the rare case of a 49-years-old woman with a tracheal bronchus causing associated with recurrent pne... | ['Bronchi', 'Bronchoscopy', 'Female', 'Humans', 'Middle Aged', 'Pneumonectomy', 'Pneumonia', 'Recurrence'] | 24,082,287 | [['A04.411.125'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.620', 'E04.928.600.600'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['C23.550.291.937']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Plasma tumor necrosis factor and post-traumatic hyperdynamic sepsis evoked by endotoxin. | To examine the role of systemic plasma tumor necrosis factor (TNF) in the septic response following trauma, an endotoxin (lipopolysaccharide (LPS)) challenge was administered to anesthetized mongrel pigs 72 h following either hemorrhagic shock/resuscitation or sham shock. For TNF to be considered a mediator, at least t... | ['Animals', 'Blood Pressure', 'Body Weight', 'Cardiac Output', 'Disease Models, Animal', 'Female', 'Hemodynamics', 'Hemorrhage', 'Leukocytes', 'Lipopolysaccharides', 'Lung', 'Male', 'Resuscitation', 'Shock, Septic', 'Swine', 'Time Factors', 'Tumor Necrosis Factor-alpha', 'Wounds and Injuries'] | 7,735,948 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E01.370.370.380.150', 'G09.330.380.124'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G09.330.380'], ['C23.550.414'], ['A11.118.637', 'A15... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Screening test of antitumor agents by human tumor cell lines in nude mice in ascitic form]. | Two kinds of, serially transplantable human tumor cell lines were established in nude mice in ascitic form. One is breast cancer cell line, poorly differentiated adenocarcinoma, Hattori strain, and the other is acute lymphocytic leukemia cell line, T-cell type, Ichikawa strain. There exists a distinct correlation betwe... | ['Adenocarcinoma', 'Animals', 'Antineoplastic Agents', 'Ascites', 'Breast Neoplasms', 'Cell Division', 'Cell Line', 'Drug Evaluation, Preclinical', 'Drug Resistance', 'Female', 'Humans', 'Leukemia, Lymphoid', 'Mice', 'Mice, Nude', 'Neoplasm Transplantation'] | 6,590,878 | [['C04.557.470.200.025'], ['B01.050'], ['D27.505.954.248'], ['C23.550.081'], ['C04.588.180', 'C17.800.090.500'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['E05.290.750', 'E05.337.550'], ['G07.690.773.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute acalculous cholecystitis following trauma. | A consecutive series of 11 patients with post-traumatic acute acalculous cholecystitis is reviewed. Three patients had sustained multiple trauma, whereas 6 patients had recently undergone alimentary tract surgery and 2 patients orthopaedic or gynaecological surgery. All patients were treated by cholecystectomy. Four ca... | ['Acute Disease', 'Adult', 'Aged', 'Cholecystectomy', 'Cholecystitis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prognosis', 'Wounds and Injuries'] | 7,104,638 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['E04.210.120.172'], ['C06.130.564.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E01.789'], ['C26']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
In vivo blockade of CTLA-4 enhances the priming of responsive T cells but fails to prevent the induction of tumor antigen-specific tolerance. | The efficacy of therapeutic vaccination for the treatment of cancer is limited by peripheral tolerance to tumor antigens. In vivo blockade of CTLA-4, a negative regulator of T cell function, can induce the regression of established tumors and can augment the tumor rejection achieved through therapeutic vaccination. The... | ['Abatacept', 'Animals', 'Antigens, CD', 'Antigens, Differentiation', 'Antigens, Neoplasm', 'B7-1 Antigen', 'B7-2 Antigen', 'CTLA-4 Antigen', 'Immune Tolerance', 'Immunoconjugates', 'Male', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred BALB C', 'Neoplasms, Experimental', 'T-Lymphocytes', 'Vaccination'] | 10,500,201 | [['D12.776.124.790.651.114.580.225', 'D12.776.377.715.548.114.580.225'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264', 'D23.101.100'], ['D23.050.285'], ['D12.776.467.150.100', 'D12.776.543.095.100', 'D23.050.301.285.100', 'D23.529.168.100'], ['D12.776.465.500', 'D12.776.467.150.200', 'D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Mobile applications related to stroke: a systematic review]. | INTRODUCTION: The incidence of stroke has increased in recent years, highlighting the role of prevention and identification of risk factors, as well as the analysis of their costs. At present, new technologies, specifically mobile applications, are considered as tools with potential benefits in patients with stroke car... | ['Arthrometry, Articular', 'Humans', 'Mobile Applications', 'Neurologic Examination', 'Outcome Assessment, Health Care', 'Patient Compliance', 'Risk Assessment', 'Stroke', 'Stroke Rehabilitation'] | 29,557,547 | [['E01.370.600.700.500', 'G11.427.760.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.900.685'], ['E01.370.376.550', 'E01.370.600.550'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['E05.318.740.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Dapagliflozin, an SGLT2 inhibitor for the treatment of type 2 diabetes. | Dapagliflozin is a selective, competitive inhibitor of sodium/glucose cotransporter 2 (SGLT2) acting to block reabsorption of filtered glucose in the kidney. Independent of pancreatic â cell function or the modulation of insulin sensitivity, this novel treatment strategy promotes glucosuria and direct lowering of plasm... | ['Benzhydryl Compounds', 'Blood Glucose', 'Clinical Trials as Topic', 'Diabetes Mellitus, Type 2', 'Drug Approval', 'Glucosides', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Sodium-Glucose Transporter 2', 'Sodium-Glucose Transporter 2 Inhibitors'] | 23,724,409 | [['D02.455.426.559.389.115'], ['D09.947.875.359.448.500'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.290.250', 'E05.337.300', 'I01.880.604.605.250.250'], ['D09.408.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Remnant-like very-low-density lipoprotein isolated from hypertriglyceridemic patients by immunoaffinity chromatography suppressed 3-hydroxy-3-methylglutaryl coenzyme A activity of cultured human skin fibroblasts. | It has been previously reported that VLDL unbound to monoclonal antibody against apoB-100 was rich in apoE, thus resembling remnant particles (J Lipid Res, 1993:33;369-380). In the current study, we have further analyzed the unbound VLDL fraction in plasma from hypertriglyceridemic patients using a mixture of monoclona... | ['Adult', 'Apolipoprotein B-48', 'Apolipoproteins B', 'Apolipoproteins E', 'Chromatography, Affinity', 'Fibroblasts', 'Humans', 'Hydroxymethylglutaryl CoA Reductases', 'Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent', 'Hypertriglyceridemia', 'Lipoproteins, VLDL', 'Male', 'Triglycerides'] | 9,074,812 | [['M01.060.116'], ['D10.532.091.300.240', 'D12.776.070.400.300.240', 'D12.776.521.120.300.240'], ['D10.532.091.300', 'D12.776.070.400.300', 'D12.776.521.120.300'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['E05.196.181.400.170'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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