Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Synthesis, growth, thermal, optical and mechanical properties of 2-Aminopyridinium 4-methylbenzoate Dihydrate. | Organic NLO material of 2-Aminopyridinium 4-methylbenzoate Dihydrate (2A4M) was synthesized using 2-Aminopyridinium and 4-methylbenzoic acid as starting materials. Single crystals of 2A4M were grown by the slow evaporation solution growth technique at room temperature using water as a solvent. The grown crystal was cha... | ['Crystallization', 'Crystallography, X-Ray', 'Hardness', 'Mechanical Phenomena', 'Optical Phenomena', 'Photons', 'Pyridinium Compounds', 'Refractometry', 'Spectroscopy, Fourier Transform Infrared', 'Temperature', 'Thermogravimetry'] | 21,978,560 | [['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['G01.374.647'], ['G01.374'], ['G01.590'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['D03.383.725.762'], ['E05.196.808', 'H01.671.617.755'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Hepatic microsomal metabolism of androst-4-ene-3,17-dione: relative importance of ring hydroxylation and aromatization in control and induced rat liver. | The purpose of these studies was to determine whether oestrogen production is a quantitatively important pathway in the hepatic microsomal metabolism of androst-4-ene-3,17-dione. The effects of the enzyme inducing agents phenobarbitone and beta-naphthoflavone on microsomal cytochrome P-450-mediated androst-4-ene-3,17-d... | ['Androstenedione', 'Animals', 'Benzoflavones', 'Cytochrome P-450 Enzyme System', 'Estradiol', 'Estrone', 'Hydroxylation', 'Male', 'Microsomes, Liver', 'Phenobarbital', 'Rats', 'Rats, Inbred Strains', 'Reference Values', 'beta-Naphthoflavone'] | 3,347,063 | [['D04.210.500.054.079.329', 'D04.210.500.578.502.112', 'D06.472.040.502.112', 'D06.472.334.851.968.875'], ['B01.050'], ['D03.383.663.283.266.450.175', 'D03.633.100.150.266.450.175'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D04.210.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Switch-on fluorescence sensing of glutathione in food samples based on a graphitic carbon nitride quantum dot (g-CNQD)-Hg²⁺ chemosensor. | Fluorescence sensing of specific biological molecules by artificial chemosensors is a versatile technique. In the present work, a switch-on fluorescence sensor for rapid, sensitive, and selective sensing of glutathione (GSH) in food samples was developed. This method was based on the g-CNQDs-Hg(2+) system, in which the... | ['Fluorescence', 'Food Analysis', 'Glutathione', 'Graphite', 'Hydrogen-Ion Concentration', 'Limit of Detection', 'Mercury', 'Quantum Dots', 'Sensitivity and Specificity', 'Spectrometry, Fluorescence'] | 25,630,354 | [['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['E05.362', 'J01.576.423.850.100'], ['D12.644.456.448'], ['D01.268.150.300', 'D01.578.300'], ['G02.300'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['E07.705', 'J01.63... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Mentorship in dermatology residency training programs: charting the right course. | Considerable attention is given to mentoring issues for dermatology trainees. Many residents consider it important to have mentors. Mentorship Programs are flourishing in residency training programs and a majority of the national dermatologic societies have established funded mentoring opportunities for residents. With... | ['Adult', 'Dermatology', 'Faculty, Medical', 'Female', 'Humans', 'Internship and Residency', 'Male', 'Mentors', 'Physicians, Women', 'Prejudice', 'Social Support', 'Societies, Medical', 'Staff Development'] | 19,624,981 | [['M01.060.116'], ['H02.403.225'], ['M01.526.485.375', 'M01.526.702.250.373', 'N02.360.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['M01.395'], ['M01.526.485.810.820', 'M01.975.790', 'N02.360.810.820'], ['F01.145.813.550', 'F01.829.595'], ['I01.880.853.500.600... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Antimicrobial resistance and molecular typing of Neisseria gonorrhoeae isolates in Kyoto and Osaka, Japan, 2010 to 2012: intensified surveillance after identification of the first strain (H041) with high-level ceftriaxone resistance. | In 2009, the first high-level ceftriaxone-resistant Neisseria gonorrhoeae strain (H041) was isolated in Kyoto, Japan. The present study describes an intensified surveillance (antimicrobial resistance and molecular typing) of Neisseria gonorrhoeae isolates in Kyoto and its neighboring prefecture Osaka, Japan, in 2010 to... | ['Anti-Bacterial Agents', 'Antigens, Bacterial', 'Azithromycin', 'Cefixime', 'Ceftriaxone', 'Ciprofloxacin', 'Epidemiological Monitoring', 'Female', 'Gonorrhea', 'Humans', 'Incidence', 'Japan', 'Male', 'Microbial Sensitivity Tests', 'Multilocus Sequence Typing', 'Neisseria gonorrhoeae', 'Penicillin G', 'beta-Lactam Res... | 23,939,890 | [['D27.505.954.122.085'], ['D23.050.161'], ['D02.540.576.500.992.050'], ['D02.065.589.099.249.190.190.115', 'D02.886.665.074.190.190.115', 'D03.633.100.300.249.190.190.115'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155', 'D03.633.100.300.249.190.190.155'], ['D03.633.100.810.835.322.186'], ['E05.318... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Protein antigen adsorption to the DDA/TDB liposomal adjuvant: effect on protein structure, stability, and liposome physicochemical characteristics. | PURPOSE: Understanding the nature of adjuvant-antigen interactions is important for the future design of efficient and safe subunit vaccines, but remains an analytical challenge. We studied the interactions between three model protein antigens and the clinically tested cationic liposomal adjuvant composed of dimethyldi... | ['Adjuvants, Immunologic', 'Adsorption', 'Animals', 'Cattle', 'Colloids', 'Glycolipids', 'Liposomes', 'Muramidase', 'Ovalbumin', 'Phase Transition', 'Protein Stability', 'Protein Structure, Secondary', 'Quaternary Ammonium Compounds', 'Serum Albumin, Bovine'] | 22,956,169 | [['D27.505.696.477.067'], ['G01.030', 'G02.020'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D20.280', 'D26.255.165'], ['D09.400.410', 'D10.390'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D08.811.277.450.642'], ['D12.644.861.557', 'D12.776.034.614', 'D12.776.256.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Is there a role for inhaled anticholinergic therapy in asthma management? | Anticholinergic therapy has long been a cornerstone of management of chronic obstructive pulmonary disease (COPD) but has not been included in treatment guidelines for asthma. In September 2015, tiotropium bromide was approved for use in adults with asthma; the indication has since been expanded to children ages 6 year... | ['Administration, Inhalation', 'Adolescent', 'Adult', 'Asthma', 'Child', 'Cholinergic Antagonists', 'Disease Management', 'Female', 'Humans', 'Male', 'Patient Selection', 'Tiotropium Bromide', 'Young Adult'] | 28,858,010 | [['E02.319.267.050'], ['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['D27.505.519.625.120.200', 'D27.505.696.577.120.200'], ['N04.590.607'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.500.653', 'N04.590.731'], ['D02.145.074.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genetic polymorphism in sympatric species of the genus Phlebotomus, with special reference to Phlebotomus perniciosus and Phlebotomus longicuspis (Diptera, Phlebotomidae). | The Random Amplified Polymorphic DNA assay was used to study genetic variation within and between five Phlebotomus species belonging to three subgenera: P. (Larroussius) ariasi, P. (L.) longicuspis, P. (L.) perniciosus, P.(Paraphlebotomus) sergenti and P. (Phlebotomus) papatasi sympatric in southern Spain and proven ve... | ['Animals', 'Cluster Analysis', 'Insect Vectors', 'Leishmaniasis', 'Phlebotomus', 'Phylogeny', 'Polymorphism, Genetic', 'Random Amplified Polymorphic DNA Technique', 'Spain'] | 11,147,032 | [['B01.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['C01.610.752.300.500', 'C01.610.858.560', 'C01.920.813', 'C17.800.838.775.560'], ['B01.050.500.131.617.720.500.500.750.781.602'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis. | BACKGROUND: Organisms living at high altitudes face low oxygen and temperature conditions; thus, the genetic mechanisms underlying the adaptations in these organisms merit investigation. The glyptosternoid fish, Creteuchiloglanis macropterus mainly inhabits regions with gradual increases in altitudes along the Nujiang ... | ['Adaptation, Physiological', 'Altitude', 'Animals', 'Base Sequence', 'Catfishes', 'Cluster Analysis', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Gene Ontology', 'Geography', 'Phylogeny', 'Principal Component Analysis', 'Rivers', 'Sequence Analysis, RNA', 'Transcriptome'] | 29,169,322 | [['G07.025', 'G16.012.500'], ['G16.500.275.058', 'N06.230.058'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.493.080'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.393.332'], ['G05.308'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Long-term astigmatic changes after phacoemulsification with single-stitch, horizontal suture closure. | We analyzed postoperative corneal astigmatism in 32 eyes followed for three years after small incision phacoemulsification with a 4 mm scleral tunnel incision and a single-stitch, horizontal suture technique. Sutures were left intact postoperatively. Mean surgically induced cylinder was 0.63 diopters (D) at one day pos... | ['Aged', 'Aged, 80 and over', 'Astigmatism', 'Cornea', 'Female', 'Follow-Up Studies', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Phacoemulsification', 'Postoperative Complications', 'Sclera', 'Suture Techniques', 'Visual Acuity'] | 8,523,288 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.744.212'], ['A09.371.060.217'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['M0... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Assessment and follow up of diabetic patients in hemodialysis]. | BACKGROUND: Despite a better management of the variables that influence the development of diabetic nephropathy there is a progressive increase in the prevalence of terminal renal failure among diabetics, whose cause is not clear.AIM: To study in a group of patients in hemodialysis, the quality of diabetes control prev... | ['Blood Glucose', 'Chile', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Diabetic Nephropathies', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Glycated Hemoglobin A', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Renal Dialysis', 'Treatment Outcome'] | 18,575,652 | [['D09.947.875.359.448.500'], ['Z01.107.757.235'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'],... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich's ataxia. | In Friedreich's ataxia (FRDA) patients, diminished frataxin (FXN) in sensory neurons is thought to yield the predominant pathology associated with disease. In this study, we demonstrate successful usage of RNA transcript therapy (RTT) as an exogenous human FXN supplementation strategy in vitro and in vivo, specifically... | ['Animals', 'Disease Models, Animal', 'Female', 'Friedreich Ataxia', 'Ganglia, Spinal', 'Gene Expression', 'Genes, Reporter', 'Humans', 'Injections, Spinal', 'Iron-Binding Proteins', 'Lipids', 'Liver', 'Luminescent Measurements', 'Mice', 'Molecular Imaging', 'Nanoparticles', 'Protein Biosynthesis', 'RNA, Messenger', 'S... | 26,883,577 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.252.700.150', 'C10.228.854.787.200', 'C10.574.500.825.200', 'C16.320.400.780.200', 'C18.452.660.300'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G05.297'], ['G05.360.340.024.340.435'], ['B01.050.150.900.649.313.988.400... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A new microsurgical technique for minimally invasive anterior lumbar interbody fusion. | STUDY DESIGN: A series of patients were prospectively studied to determine the morbidity and possible complications of minimally invasive anterior lumbar interbody fusion by two new microsurgical approaches (retroperitoneal for segments L2-L3, L3-L4, and L4-L5, and transperitoneal for L5-S1).OBJECTIVES: To investigate ... | ['Adult', 'Aged', 'Feasibility Studies', 'Female', 'Humans', 'Low Back Pain', 'Lumbar Vertebrae', 'Male', 'Medical Illustration', 'Microsurgery', 'Middle Aged', 'Postoperative Complications', 'Postoperative Period', 'Radiography', 'Spinal Fusion', 'Treatment Outcome'] | 9,089,943 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['A02.835.232.834.519'], ['H02.385', 'J01.897.280.500.480', 'K01.093.410', 'L01.178.820.090.480'], ['E04.494', 'E05.591.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Humanities [K]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
The role of antepartum testing in the management of postterm pregnancies with heavy meconium in early labor. | The documented association between heavy meconium in early labor and increased perinatal morbidity and mortality has alerted physicians to the presence of a potential high-risk fetal condition and to the possible need for immediate fetal blood pH determination. The purpose of this study was to determine whether antepar... | ['Amniotic Fluid', 'Delivery, Obstetric', 'Female', 'Fetal Distress', 'Heart Rate, Fetal', 'Humans', 'Hydrogen-Ion Concentration', 'Meconium', 'Pregnancy', 'Pregnancy, Prolonged', 'Prenatal Diagnosis', 'Risk', 'Ultrasonography', 'Uterine Contraction'] | 3,554,066 | [['A12.098', 'A16.378.149'], ['E04.520.252'], ['C23.888.380'], ['G09.330.380.500.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['A12.459.529', 'A16.378.529'], ['G08.686.784.769'], ['C13.703.805'], ['E01.370.378.630'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Monitoring cerebral perfusion during carotid endarterectomy. | Transcranial pulsed Doppler ultrasound was used to monitor blood velocity in the middle cerebral artery (MCA) of two patients during ipsilateral carotid endarterectomy. In the first patient the ultrasound data demonstrated a non-functioning shunt which was corrected by repositioning the distal end of the shunt. In the ... | ['Aged', 'Arterial Occlusive Diseases', 'Carotid Artery Diseases', 'Carotid Artery, Internal', 'Cerebrovascular Circulation', 'Endarterectomy', 'Humans', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Regional Blood Flow', 'Ultrasonography'] | 2,182,640 | [['M01.060.116.100'], ['C14.907.137'], ['C10.228.140.300.200', 'C14.907.253.123'], ['A07.015.114.186.200.230'], ['G09.330.100.159'], ['E04.100.814.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520'], ['G09.330.100.780'], ['E01.370.350.850']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Molecular characterization of alpha-thalassemia determinants, beta-thalassemia alleles, and beta S haplotypes among Kuwaiti Arabs. | Using amplification, allele-specific oligonucleotide (ASO) hybridization and DNA sequencing we have documented the molecular basis of 64 alpha- and 123 beta-thalassemia (thal) chromosomes, and the haplotypes of 18 beta S chromosomes from patients followed in three hospitals in Kuwait. Of the 30 chromosomes from 15 pati... | ['Anemia, Sickle Cell', 'Arab World', 'Base Sequence', 'Female', 'Globins', 'Humans', 'Kuwait', 'Male', 'Molecular Sequence Data', 'Pedigree', 'alpha-Thalassemia', 'beta-Thalassemia'] | 7,701,914 | [['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['I01.076.201.450.226.200'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.422.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.425'], ['L01.453.245.667'], ['E05.393.673'], ['C15.378.07... | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 |
Enhanced osteoclastic resorption and responsiveness to mechanical load in gap junction deficient bone. | Emerging evidence suggests that connexin mediated gap junctional intercellular communication contributes to many aspects of bone biology including bone development, maintenance of bone homeostasis and responsiveness of bone cells to diverse extracellular signals. Deletion of connexin 43, the predominant gap junction pr... | ['Animals', 'Biomechanical Phenomena', 'Bone Density', 'Bone Resorption', 'Bone and Bones', 'Cell Communication', 'Cell Line', 'Connexin 43', 'Gap Junctions', 'Gene Deletion', 'Humans', 'Male', 'Mechanical Phenomena', 'Mice', 'Osteoclasts', 'Osteocytes', 'Osteogenesis', 'Osteoprotegerin', 'RANK Ligand', 'RNA, Messenger... | 21,897,843 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['G11.427.100'], ['C05.116.264', 'G11.427.213.150'], ['A02.835.232', 'A10.165.265'], ['G04.085'], ['A11.251.210'], ['D12.776.543.585.250.200'], ['A11.284.149.165.420.471'], ['G05.365.590.762.320', 'G05.558.800.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.37... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Zenker's diverticulum: carbon dioxide laser endoscopic surgery. | Nowadays endoscopic diverticulotomy is the surgical approach of the first choice in treatment of Zenker's diverticulum. We report our experience with this procedure and try to sum up recent recommendations for management of surgery and postoperative care. Data of 34 patients with Zenker's diverticulum, treated by endos... | ['Adult', 'Aged', 'Aged, 80 and over', 'Esophagoscopy', 'Female', 'Follow-Up Studies', 'Humans', 'Laser Therapy', 'Male', 'Middle Aged', 'Prospective Studies', 'Retrospective Studies', 'Time Factors', 'Zenker Diverticulum'] | 24,729,975 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.372.250.250.275', 'E01.370.388.250.250.250.260', 'E04.210.240.250.260', 'E04.502.250.250.250.260'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Intrauterine bacterial and mycotic infections in cows]. | Bacteriologic, mycologic, and serologic investigations of cows and calves and three experiments with rabbits were carried out to shed light on the bacteriology and mycology of the intrauterine infections in cows. The following organisms were isolated from the investigated cows that exhibited disturbances in their repro... | ['Abortion, Veterinary', 'Amniotic Fluid', 'Animals', 'Bacterial Infections', 'Cattle', 'Cattle Diseases', 'Endometritis', 'Feces', 'Female', 'Mycoses', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Uterine Diseases', 'Uterus', 'Vagina'] | 6,880,018 | [['C13.703.039.422', 'C22.021'], ['A12.098', 'A16.378.149'], ['B01.050'], ['C01.150.252'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C13.351.500.056.750.249', 'C13.351.500.852.299'], ['A12.459'], ['C01.150.703'], ['G08.686.784.769'], ['C01.674', 'C13.703.700'], ['C13.351.500.852'], ['A05.360.319.679'], ['... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of v-fms and c-fms in the hemopoietic cell line FDC-P1. | A hemopoietic cell line FDC-P1 that requires either IL-3 or GM-CSF to survive and proliferate was infected with retroviruses that expressed either c-fms, which encodes the receptor for M-CSF, or v-fms, which is an oncogenic derivative of c-fms. The expression of c-fms allowed FDC-P1 to grow in the absence of IL-3 or GM... | ['Animals', 'Base Sequence', 'Cell Division', 'Colony-Stimulating Factors', 'Gene Expression', 'Genetic Vectors', 'Hematopoietic Stem Cells', 'Interleukin-3', 'Macrophage Colony-Stimulating Factor', 'Molecular Sequence Data', 'Oncogene Protein gp140(v-fms)', 'Proto-Oncogene Proteins', 'Receptor, Macrophage Colony-Stimu... | 2,140,043 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D12.644.276.374.410.240', 'D12.776.395.240', 'D12.776.467.374.410.240', 'D23.529.374.410.240'], ['G05.297'], ['G05.360.337'], ['A11.148.378', 'A11.872.378', 'A15.378.316.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Lipid peroxidation in early experimental diabetes in rats: effects of diabetes and insulin. | The degree of lipid peroxidation was measured in organs from diabetic rats receiving no treatment, and in those from insulin-treated diabetic rats and controls. Lipid peroxidation was measured as organ content of malondialdehyde, a degradation product of polyunsaturated fatty acids. In the kidney, lipid peroxidation wa... | ['Animals', 'Diabetes Mellitus, Experimental', 'Female', 'Insulin', 'Kidney', 'Lipid Peroxides', 'Liver', 'Malondialdehyde', 'Rats', 'Rats, Inbred Strains'] | 1,595,332 | [['B01.050'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A05.810.453'], ['D01.248.497.158.685.750.637', 'D01.339.431.374.637', 'D01.650.550.750.600', 'D02.389.338.450', 'D10.440'], ['A03.620'], ['D02.047.700'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cerebrospinal fluid IgG changes in subacute sclerosing panencephalitis in the various stages of the disease and during isoprinosine therapy. | The cerebrospinal fluid (CSF) levels of IgG and the separation of the CSF and serum proteins by isoelectric focusing (IEF) were studied in 5 patients with subacute sclerosing panencephalitis (SSPE). Oligoclonal IgG fractions were found in the CSF of all the patients. The CSF IgG, IgG-Index and IgG SYN values were highe... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Immunoglobulin G', 'Inosine', 'Inosine Pranobex', 'Isoelectric Focusing', 'Male', 'Subacute Sclerosing Panencephalitis'] | 6,174,478 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D03.633.100.759.590.616', 'D13.570.583.616', 'D13.570.800.573'], ['D02.065.199.092.450', 'D02.092.146.113.... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Differential effects of chronic treatment with haloperidol and clozapine on the level of preprosomatostatin mRNA in the striatum, nucleus accumbens, and frontal cortex of the rat. | 1. The goal of this work was to determine the effects of typical and atypical neuroleptics on the level of preprosomatostatin messenger RNA (mRNA) in regions of the rat brain innervated by dopaminergic neurons. 2. Quantitative in situ hybridization histochemistry was used to measure the levels of mRNA encoding preproso... | ['Animals', 'Brain', 'Clozapine', 'Corpus Striatum', 'Dibenzazepines', 'Frontal Lobe', 'Gene Expression Regulation', 'Haloperidol', 'Male', 'Nucleic Acid Hybridization', 'Nucleus Accumbens', 'Protein Precursors', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains', 'Somatostatin'] | 1,970,756 | [['B01.050'], ['A08.186.211'], ['D03.633.300.240.220'], ['A08.186.211.200.885.287.249.487'], ['D03.633.300.240'], ['A08.186.211.200.885.287.500.270'], ['G05.308'], ['D02.522.352.506'], ['E05.393.661', 'G02.111.611'], ['A08.186.211.200.885.287.249.487.775.500'], ['D12.776.811'], ['D13.444.735.544'], ['B01.050.150.900.64... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of angiotensin II on visual neurons in the superficial laminae of the hamster's superior colliculus. | Superficial layer superior colliculus (SC) neurons were recorded extracellularly with multibarreled recording/ejecting micropipettes. Angiotensin II was delivered via micropressure ejection during visual stimulation (n = 215 cells), or during electrical stimulation of either the optic chiasm (OX; n = 150 cells) or visu... | ['Angiotensin I', 'Angiotensin II', 'Animals', 'Cricetinae', 'Electric Stimulation', 'Glutamic Acid', 'Iontophoresis', 'Magnesium', 'Neurons', 'Photic Stimulation', 'Receptors, Angiotensin', 'Superior Colliculi', 'Visual Cortex', 'Visual Pathways'] | 7,841,124 | [['D06.472.699.094.075', 'D12.644.400.070.075', 'D12.644.456.073.021', 'D12.644.548.058.075', 'D12.776.631.650.070.075', 'D23.469.050.050.025'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['B01.050.150.900.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A defective autologous mixed lymphocyte reaction in patients with idiopathic portal hypertension. | The aetiology of idiopathic portal hypertension or hepatoportal sclerosis is unknown. In view of the indirect evidence for underlying immunologic abnormalities 14 patients (all middle-aged females) were studied. Various auto-antibodies were demonstrated in seven patients and high levels of serum immunoglobulins, either... | ['Antibodies, Antinuclear', 'Autoantibodies', 'Female', 'Humans', 'Hypertension, Portal', 'Immunoglobulins', 'Liver Cirrhosis', 'Lymphocyte Activation', 'Lymphocyte Culture Test, Mixed', 'Middle Aged', 'Rosette Formation', 'Splenomegaly', 'T-Lymphocytes'] | 1,535,230 | [['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Are patients with POEMS syndrome at increased risk of Salmonella aortitis? | We report a case of Salmonella infectious aortitis in a patient with POEMS (peripheral neuropathy, organomegaly, endocrinopathy, M-protein and skin changes) syndrome, possibly indicating that vasculopathy associated with POEMS syndrome may increase the risk of Salmonella endovascular infection. | ['Aged', 'Aortic Aneurysm, Abdominal', 'Aortitis', 'Humans', 'Male', 'POEMS Syndrome', 'Salmonella Infections', 'Shock, Septic'] | 18,951,055 | [['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['C14.907.109.320', 'C14.907.940.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.668.829.800.700', 'C15.378.147.780.750', 'C16.131.077.703', 'C20.683.780.750'], ['C01.150.252.400.310.821'], ['C01.757.800', 'C23.550.470.790.500.800', 'C2... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Factors affecting patient satisfaction at the Lagos State University Teaching Hospital Dental Clinic. | BACKGROUND: Satisfaction is important in dental care because satisfaction with care alleviates dental anxiety, influences patients' compliance and is an important indicator of quality of care.OBJECTIVES: This study was designed to determine the factors that contribute to satisfaction with dental care among patients att... | ['Adolescent', 'Adult', 'Aged', 'Chi-Square Distribution', 'Dental Care', 'Dental Clinics', 'Female', 'Hospitals, Teaching', 'Hospitals, University', 'Humans', 'Male', 'Middle Aged', 'Nigeria', 'Patient Satisfaction', 'Quality of Health Care', 'Socioeconomic Factors', 'Statistics, Nonparametric', 'Surveys and Questionn... | 23,909,091 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E06.170', 'N02.421.240.190'], ['N02.278.192.250'], ['N02.278.020.300', 'N02.278.421.639'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Schwann cells responding to primary demyelination in vivo express p75NTR and c-erbB receptors: a light and electron immunohistochemical study. | We have used quantitative and qualitative light microscope immunohistochemistry to examine the expression of p75NTR and c-erbB receptors in Schwann cells in a demyelinating lesion induced by the intraneural injection of lysophosphatidyl choline (LPC). We report that levels of p75NTR, c-erbB2 and c-erbB4, as assessed us... | ['Animals', 'Cattle', 'Demyelinating Diseases', 'ErbB Receptors', 'Immunohistochemistry', 'Lysophosphatidylcholines', 'Mice', 'Microscopy, Immunoelectron', 'Proliferating Cell Nuclear Antigen', 'Rabbits', 'Rats', 'Receptor, ErbB-2', 'Receptor, ErbB-4', 'Receptor, Nerve Growth Factor', 'Receptors, Nerve Growth Factor', ... | 9,368,881 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C10.314'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.2... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of Helicobacter in gastric biopsies by PCR based on 16S rDNA sequences: a matter of little significance for the prediction of H. pylori-associated gastritis? | The aim of the present study was to correlate molecular evidence of the presence of Helicobacter pylori in gastric biopsy samples, based on analysis of 16S rDNA, vacuolating toxin (vacA), urease A (ureA) and cagA genes, with the clinical, histological and serological findings in patients with H. pylori-associated gastr... | ['Adult', 'Aged', 'Antibodies, Bacterial', 'Antigens, Bacterial', 'Bacterial Proteins', 'Base Sequence', 'Biopsy', 'DNA Primers', 'DNA, Ribosomal', 'Female', 'Gastritis', 'Genotype', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Polymerase Chain Reaction'... | 9,877,190 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Metabolic syndrome and atherosclerotic events in renal transplant recipients. | BACKGROUND: Metabolic syndrome (MS) is a known cardiovascular risk factor in the general population. We explored the influence of MS on the occurrence of atherosclerotic events (AEs) after renal transplantation.METHODS: Three hundred thirty-seven renal transplant recipients were included in the study. Various parameter... | ['Adult', 'Atherosclerosis', 'Female', 'Follow-Up Studies', 'Graft Rejection', 'Humans', 'Kidney Transplantation', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Multivariate Analysis', 'Postoperative Complications', 'Retrospective Studies', 'Risk Assessment', 'Time Factors'] | 17,589,340 | [['M01.060.116'], ['C14.907.137.126.307'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['C18.452.394.968.500.570', 'C18.452.625'], ['M01.060.116.630... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reflux in untreated achalasia patients. | We made a prospective assessment of acid exposure in the distal esophagus in 48 consecutive untreated patients with achalasia using 24-h ambulatory esophageal pH studies. The majority of patients (38/48) experienced reflux that was within reported values for normal controls (total time pH < 4.0, 1.8 +/- 1.9%). Approxim... | ['Adult', 'Aged', 'Aged, 80 and over', 'Dilatation', 'Esophageal Achalasia', 'Esophagogastric Junction', 'Esophagus', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Lactobacillus', 'Male', 'Manometry', 'Middle Aged', 'Prospective Studies'] | 7,884,182 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.284'], ['C06.405.117.119.500.432'], ['A03.556.875.500.414', 'A03.556.875.875.330'], ['A03.556.875.500'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
What a difference a year makes: the impact of the district nursing specialist practice programme. | District nursing has a long history as a service that provides care for patients in their home environment. Demographic changes and a need to optimise out of hospital care has impacted on the acuity of patients supported and the complexity of caseload management. District nurses, in order to effectively manage such inc... | ['Adult', 'Assertiveness', 'Attitude of Health Personnel', 'Case Management', 'Clinical Competence', 'Community Health Nursing', 'Curriculum', 'Education, Nursing, Continuing', 'England', 'Female', 'Humans', 'Interviews as Topic', 'Leadership', 'Male', 'Middle Aged', 'Scotland', 'Specialties, Nursing', 'Surveys and Que... | 30,156,899 | [['M01.060.116'], ['F01.752.049'], ['F01.100.050', 'N05.300.100'], ['N04.590.233.624.250'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['H02.478.676.150', 'N02.421.143.150'], ['I02.158'], ['I02.358.212.450', 'I02.358.462.399'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. | In this article, we have characterized and compared gene expression profiles from laser capture microdissected neurons in six functionally and anatomically distinct regions from clinically and histopathologically normal aged human brains. These regions, which are also known to be differentially vulnerable to the histop... | ['Aged', 'Aged, 80 and over', 'Aging', 'Alzheimer Disease', 'Brain', 'Female', 'Gene Expression', 'Gene Expression Profiling', 'Humans', 'Immunohistochemistry', 'Male', 'Nerve Tissue Proteins', 'Neurons', 'Oligonucleotide Array Sequence Analysis', 'RNA'] | 17,077,275 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211'], ['G05.297'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.51... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Combination therapy with an antioxidant and a corticosteroid prevents autoimmune diabetes in NOD mice. | Oxygen free radicals have been implicated as mediators of pancreatic islet beta cell damage in autoimmune, insulin-dependent diabetes mellitus (IDDM). In this study, we show that the antioxidant, probucol, produced only a small decrease in diabetes incidence in nonobese diabetic (NOD) mice, an animal model for human ID... | ['Animals', 'Anti-Inflammatory Agents', 'Antioxidants', 'Blood Glucose', 'Diabetes Mellitus, Type 1', 'Disease Models, Animal', 'Drug Synergism', 'Drug Therapy, Combination', 'Female', 'Incidence', 'Insulin', 'Mice', 'Mice, Inbred NOD', 'Pregnenediones', 'Probucol'] | 1,453,877 | [['B01.050'], ['D27.505.954.158'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D09.947.875.359.448.500'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.968.477'], ['E02.319.310'], ['E05.318.308.985.525.375', 'N01.224.935.597.500'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Role of prostaglandins in tumour necrosis factor induced weight loss. | Administration of either tumour necrosis factor alpha (TNF-alpha) or 16,16-dimethylprostaglandin E2 (PGE2) to female NMRI mice caused a decrease in body weight accompanied by a reduction in both food and water intake and a decrease in carcass water content. A single injection of TNF-alpha caused an enhanced production ... | ['16,16-Dimethylprostaglandin E2', 'Animals', 'Dinoprostone', 'Female', 'Indomethacin', 'Mice', 'Recombinant Proteins', 'Tumor Necrosis Factor-alpha', 'Weight Loss'] | 2,803,915 | [['D10.251.355.255.550.775.450.300', 'D23.469.050.175.725.775.450.300', 'D23.469.700.660.200'], ['B01.050'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['D03.633.100.473.420'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.828'], ['D12.644.276.374.500.800', 'D12.644.276.374.750.626', 'D12.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modeling long-term exposure of the whole population to chemicals in food. | This paper discusses a statistical exposure model (STEM) that can be used to estimate the percentage of the population exceeding ingestion intake criteria (e.g., ADI or TDI). In addition, STEM may be linked to toxicokinetic models to evaluate the interindividual variability in internal doses that results from variabili... | ['Cadmium', 'Dioxins', 'Environmental Exposure', 'Food Contamination', 'Humans', 'Models, Statistical', 'Netherlands'] | 8,259,442 | [['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D02.309.500', 'D03.383.231'], ['N06.850.460.350'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], [... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
3D-QSAR and cell wall permeability of antitubercular nitroimidazoles against Mycobacterium tuberculosis. | Inhibitory activities of monocyclic nitroimidazoles against Mycobacterium tuberculosis (Mtb) deazaflavin-dependent nitroreductase (DDN) were modeled by using docking, pharmacophore alignment and comparative molecular similarity indices analysis (CoMSIA) methods. A statistically significant model obtained from CoMSIA wa... | ['Antitubercular Agents', 'Cell Wall', 'Mycobacterium tuberculosis', 'Nitroimidazoles', 'Permeability', 'Quantitative Structure-Activity Relationship'] | 24,217,328 | [['D27.505.954.122.085.255'], ['A11.284.183'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['D02.640.672', 'D03.383.129.308.658'], ['G02.723'], ['G02.111.830.500', 'G07.690.773.997.500']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The epidemiology of severe and catastrophic injuries in BASE jumping. | OBJECTIVE: To report the demographic characteristics, injury rate, severity, and morbidity in BASE jumping.DESIGN: Cross-sectional survey.SETTING: BASE jumping group meetings from 2006 to 2010.PARTICIPANTS: Heterogenic group of 102 International BASE jumpers.ASSESSMENT OF RISK FACTORS: Injuries reported as function of ... | ['Adult', 'Athletic Injuries', 'Aviation', 'Back Injuries', 'Craniocerebral Trauma', 'Female', 'Humans', 'Incidence', 'Lower Extremity', 'Male', 'Middle Aged', 'Risk Factors', 'Severity of Illness Index', 'Thoracic Injuries', 'Young Adult'] | 22,450,590 | [['M01.060.116'], ['C26.115'], ['J01.937.285'], ['C26.117'], ['C10.900.300', 'C26.915.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['A01.378.610'], ['M01.060.116.630'], ['E05.318.740.600.800.725'... | ['Named Groups [M]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Characterization of nitrite uptake in Arabidopsis thaliana: evidence for a nitrite-specific transporter. | Nitrite-specific plasma membrane transporters have been described in bacteria, algae and fungi, but there is no evidence of a nitrite-specific plasma membrane transporter in higher plants. We have used 13NO2(-) to characterize nitrite influx into roots of Arabidopsis thaliana. Hydroponically grown Arabidopsis mutants, ... | ['Ammonium Compounds', 'Anion Transport Proteins', 'Arabidopsis', 'Arabidopsis Proteins', 'Ion Transport', 'Mutation', 'Nitrates', 'Nitrites', 'Nitrogen', 'Plant Roots'] | 23,763,619 | [['D01.625.062'], ['D12.776.157.530.450.074', 'D12.776.543.585.450.074'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G03.143.500'], ['G05.365.590'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D01.248.497.158.635', 'D01.625.600.600', 'D02.633'], ['D01.268.604', 'D01.362.625'], ['A18.40... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis on long-term trends of cervical cancer mortality and years of life lost in Tianjin, 1999-2015]. | Objective: To analyze the mortality and years of life lost (YLL) trends of cervical cancer in Tianjin, and provide references for the research and prevention programs of cervical cancer. Methods: Mortality rate, standard mortality rate, cumulative rate (0-74 years-old) and truncated rate (35-64 years-old) of cervical c... | ['Adolescent', 'Adult', 'Aged', 'China', 'Female', 'Humans', 'Incidence', 'Middle Aged', 'Mortality', 'Regression Analysis', 'Residence Characteristics', 'Survival Rate', 'Uterine Cervical Neoplasms', 'Young Adult'] | 30,669,733 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hair loss. Common congenital and acquired causes. | Hair loss is a common problem likely to be encountered by a clinical practitioner. The most frequent causes of hair loss in pediatric patients include tinea capitis, alopecia areata, traction alopecia, and trichotillomania. In the adult population, causes to be considered are alopecia areata and hair loss associated wi... | ['Adolescent', 'Alopecia', 'Alopecia Areata', 'Androgens', 'Child', 'Diagnosis, Differential', 'Female', 'Hair', 'Humans', 'Infant', 'Male', 'Scalp', 'Tinea Capitis', 'Trichotillomania'] | 3,960,800 | [['M01.060.057'], ['C17.800.329.937.122', 'C23.300.035'], ['C17.800.329.937.122.147'], ['D27.505.696.399.472.161'], ['M01.060.406'], ['E01.171'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A01.456.810'], ['C01.150.703.302.720.730', 'C01.800.200.720.730', 'C17.800.738.708', 'C17.800... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Opisthotonus in neurosyphilis: a case report. | A 40-year-old woman presented via ambulance to our Emergency Department (ED) for decreased level of consciousness. The patient's husband reported declining cognitive ability over the prior 3 months, and a hospital visit for left leg weakness 5 months earlier. In the ED, the patient exhibited recurrent opisthotonus epis... | ['Adult', 'Dystonic Disorders', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Neurosyphilis', 'Sexually Transmitted Diseases, Bacterial'] | 18,547,774 | [['M01.060.116'], ['C10.228.662.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C01.150.252.223.600', 'C01.150.252.400.794.840.500.750', 'C01.150.252.400.840.500.750', 'C01.207.180.600', 'C10.228.228.180.600'], ['C01.150.252.734', 'C01.221.812.281', 'C01.778.281', 'C12.294.668.281', '... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Physicians' beliefs about effectiveness of cancer screening tests: a national survey of family physicians, general internists, and obstetrician-gynecologists. | OBJECTIVE: To study physicians' beliefs about the effectiveness of different tests for cancer screening.METHODS: Data were examined from the Women's Health Survey of 1574 Family Medicine, Internal Medicine, and Obstetrics-Gynecology physicians to questions about their level of agreement about the clinical effectiveness... | ['Adult', 'Attitude of Health Personnel', 'Early Detection of Cancer', 'Female', 'Guideline Adherence', 'Health Care Surveys', 'Humans', 'Male', 'Middle Aged', 'Physicians', "Practice Patterns, Physicians'", 'United States'] | 25,038,531 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['E01.390.500'], ['N04.761.337', 'N05.715.360.395'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.526.485.810', 'N02.360.810']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Diffuse lipogranulomatosis involving soft tissues of the head and neck due to multiple self-injections of mineral oil. | We describe imaging findings of a 45-year-old man with a 6-month history of gradually increasing diffuse swelling of the neck. CT showed diffuse thickening and infiltration of the superficial and deep soft tissues bilaterally. On further investigation of his history, the patient stated that he had injected mineral oil ... | ['Erdheim-Chester Disease', 'Head', 'Humans', 'Injections, Subcutaneous', 'Male', 'Middle Aged', 'Mineral Oil', 'Neck', 'Radiography', 'Self Medication'] | 18,617,587 | [['C15.604.250.410.224'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.620'], ['M01.060.116.630'], ['D02.455.699.500'], ['A01.598'], ['E01.370.350.700'], ['E02.319.900', 'E02.900.900']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The magnetic properties of myoglobin as studied by NMR spectroscopy. | Deoxymyoglobin has been investigated by NMR spectroscopy to determine the magnetic anisotropy through pseudocontact shifts and the total magnetic susceptibility through Evans measurements. The magnetic anisotropy values were found to be Deltachi(ax)=-2.03+/-0.08 x 10(-32) m(3) and Deltachi(rh)=-1.02+/-0.09 x 10(-32) m(... | ['Anisotropy', 'Binding Sites', 'Ferric Compounds', 'Models, Molecular', 'Myoglobin', 'Nuclear Magnetic Resonance, Biomolecular'] | 12,772,306 | [['G01.590.040', 'G02.050'], ['G02.111.570.120'], ['D01.490.100'], ['E05.599.595'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['E05.196.867.519.550']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A sequence of basic residues in the porcine circovirus type 2 capsid protein is crucial for its co-expression and co-localization with the replication protein. | Porcine circovirus type 2 (PCV2) encodes two major proteins: the replication protein (Rep) and the capsid protein (Cap). Cap displays a conserved stretch of basic residues situated on the inside of the capsid, whose role is so far unknown. We used a reverse-genetics approach to investigate its function and found that m... | ['Animals', 'Capsid Proteins', 'Cell Line', 'Circovirus', 'DNA, Viral', 'Gene Expression Regulation, Viral', 'Genotype', 'Mutation', 'Protein Transport', 'RNA, Messenger', 'RNA, Viral', 'Swine', 'Virus Replication'] | 26,415,571 | [['B01.050'], ['D12.776.964.970.600.550'], ['A11.251.210'], ['B04.280.120.150'], ['D13.444.308.568'], ['G05.308.385'], ['G05.380'], ['G05.365.590'], ['G03.143.700'], ['D13.444.735.544'], ['D13.444.735.828'], ['B01.050.150.900.649.313.500.880'], ['G06.920.925']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The child as proband. High prevalence of unrecognized and untreated hyperlipidemia in parents of hyperlipidemic children. | The authors evaluated the lipids of parents of hypercholesterolemic children to assess the prevalence of unrecognized and/or untreated hyperlipidemia. Biologic parents of 34 children had measurements of total cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides (n = 47) or total cholesterol only (... | ['Adult', 'Child', 'Cholesterol', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Female', 'Humans', 'Hyperlipidemias', 'Lipids', 'Male', 'Middle Aged', 'Prevalence', 'Triglycerides'] | 2,791,435 | [['M01.060.116'], ['M01.060.406'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['B01.050.150.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fast nonlinear region localisation for nonlinear dielectric spectroscopy of biological suspensions. | The nonlinear properties of biological suspensions have been previously presented as a bulk phenomenon without the influences of the electrodes. However, some authors have showed that the behaviour of a biological suspension is due to the nonlinear characteristics of the electrode-electrolyte interface (EEI), which is ... | ['Dielectric Spectroscopy', 'Fourier Analysis', 'Nonlinear Dynamics', 'Reproducibility of Results', 'Saccharomyces cerevisiae', 'Time Factors'] | 23,796,533 | [['E05.196.867.335'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['E05.599.850', 'H01.548.675'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease. | In patients with nonalcoholic fatty liver disease (NAFLD), a liver biopsy remains the only reliable way to differentiate simple steatosis from nonalcoholic steatohepatitis (NASH). Noninvasive methods are urgently needed. Increasing evidence suggests hepatocyte apoptosis is a key mediator of liver injury in NAFLD. The a... | ['Apoptosis', 'Biomarkers', 'Biopsy', 'Diagnosis, Differential', 'Fatty Liver', 'Female', 'Hepatocytes', 'Humans', 'Immunohistochemistry', 'Keratins', 'Male', 'Middle Aged', 'Prognosis', 'ROC Curve', 'Severity of Illness Index'] | 16,799,979 | [['G04.146.954.035'], ['D23.101'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.171'], ['C06.552.241'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.5... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Dual-site recognition of different extracellular matrix components by anti-angiogenic/neurotrophic serpin, PEDF. | Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor (serpin) superfamily, possesses anti-angiogenic and neurotrophic activities. PEDF has been reported to bind to extracellular matrix (ECM) components such as collagens and glycosaminoglycans (GAGs). In this study, to determine the bindin... | ['Animals', 'Base Sequence', 'Binding Sites', 'Circular Dichroism', 'DNA Primers', 'Extracellular Matrix Proteins', 'Eye Proteins', 'Mice', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Neovascularization, Physiologic', 'Nerve Growth Factors', 'Proteins', 'Recombinant Proteins', 'Serpins'] | 12,641,447 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.196.867.151'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D12.776.860.300'], ['D12.776.306'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.595'], ['E05.393.420.601.575'], ['G09.330.630'], ['D... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Practical tips for office surgery. Commonsense advice from a plastic surgeon. | Performing office surgery well is an art. You can accomplish this by being attentive to several factors. These include, but are not limited to, providing an office environment that is pleasant, restful, and happy; using proper lighting, instruments, and suture techniques; using gentle techniques for local infiltration ... | ['Ambulatory Surgical Procedures', 'Humans', 'Surgery, Plastic', 'Surgical Instruments', 'Suture Techniques', 'Wounds and Injuries'] | 6,348,720 | [['E04.030'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.788'], ['E07.858.700'], ['E04.987.775'], ['C26']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term recovery after bone marrow stromal cell treatment of traumatic brain injury in rats. | OBJECT: This study was designed to follow the effects of bone marrow stromal cell (BMSC) administration in rats after traumatic brain injury (TBI) for a 3-month period.METHODS: Forty adult female Wistar rats were injured by a controlled cortical impact and, 1 week later, were injected intravenously with one of three di... | ['Animals', 'Bone Marrow Transplantation', 'Brain Injuries', 'Cell Proliferation', 'Female', 'Immunohistochemistry', 'Rats', 'Rats, Wistar', 'Stromal Cells', 'Treatment Outcome'] | 16,509,501 | [['B01.050'], ['E02.095.147.725.040', 'E04.936.580.040'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Daily intake of inorganic arsenic and some organic arsenic species of Japanese subjects. | The daily dietary intake of inorganic arsenic (InAs) and some of organic arsenic (OrAs) species of Japanese subjects were estimated by determining the concentrations of As species in two different sets of total diet sample: duplicated diet samples collected from 25 subjects in Japan and a certified reference material w... | ['Arsenic', 'Chromatography, Liquid', 'Environmental Exposure', 'Humans', 'Inorganic Chemicals', 'Japan', 'Mass Spectrometry', 'Organic Chemicals'] | 22,617,717 | [['D01.268.513.249'], ['E05.196.181.400'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01'], ['Z01.252.474.463', 'Z01.639.595'], ['E05.196.566'], ['D02']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Long-term treatment with oxcarbazepine in clinical practice. | Oxcarbazepine (up to 1800 mg daily orally) was given for 12 months to 61 adult epileptic patients in clinical practice, as monotherapy (n=52) or adjunctive therapy (n=9). Patients on monotherapy became seizure-free (76.9%) or experienced > or = 75% seizure rate reduction, with two exceptions. In the adjunctive therapy ... | ['Adolescent', 'Adult', 'Anticonvulsants', 'Carbamazepine', 'Epilepsy', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Oxcarbazepine', 'Retrospective Studies', 'Treatment Outcome'] | 16,324,237 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.427.080'], ['D03.633.300.240.127'], ['C10.228.140.490'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.633.300.240.127.500'], ['E05.318.372.500.500.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin. | Tetrahydrobiopterin is a cofactor for nitric oxide synthase. In low concentrations of this cofactor, nitric oxide synthase is known to produce less nitric oxide and, correspondingly, enhanced quantities of the oxidant species, hydrogen peroxide. In this study, we tested the hypothesis that an exogenous tetrahydrobiopte... | ['Acetylcholine', 'Animals', 'Aorta, Thoracic', 'Diabetes Mellitus, Experimental', 'Endothelium, Vascular', 'In Vitro Techniques', 'Male', 'Muscle Contraction', 'Muscle Relaxation', 'Muscle, Smooth, Vascular', 'Nitric Oxide Synthase', 'Nitroglycerin', 'Pterins', 'Rats', 'Rats, Sprague-Dawley'] | 9,007,664 | [['D02.092.211.111'], ['B01.050'], ['A07.015.114.056.372'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['A07.015.700.500', 'A10.272.491.355'], ['E05.481'], ['G11.427.494'], ['G11.427.494.554'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['D08.811.682.664.500.772'], ['D02.640.636'], ['D03... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Localization of the decoding region on the 30S Escherichia coli ribosomal subunit by affinity immunoelectron microscopy. | The decoding region of the Escherichia coli ribosome has been localized by affinity immunoelectron microscopy. Valyl-tRNA1Val, derivatized at the alpha-amino end with the dinitrophenyl group, was bound to the ribosomal P site of 70S ribosomes and crosslinked specifically to 16S RNA by 310- to 325-nm irradiation. Previo... | ['Dinitrophenols', 'Escherichia coli', 'Immunoassay', 'Microscopy, Electron', 'Protein Biosynthesis', 'RNA, Ribosomal', 'RNA, Transfer', 'Ribosomes', 'Valine'] | 375,223 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microtubule regulation of cell surface receptor topography during granulosa cell differentiation. | A possible role for cytoplasmic microtubules in modulating lectin binding site topography has been examined during the hormone-directed differentiation of rat ovarian granulosa cells in vitro. Indirect immunofluorescence staining with anti-tubulin antibodies indicates that undifferentiated cultured granulosa cells cont... | ['Animals', 'Cell Differentiation', 'Cells, Cultured', 'Cilia', 'Colchicine', 'Concanavalin A', 'Female', 'Fluorescent Antibody Technique', 'Granulosa Cells', 'Microscopy, Electron', 'Microtubules', 'Prolactin', 'Rats', 'Rats, Inbred Strains', 'Receptors, Concanavalin A'] | 6,363,181 | [['B01.050'], ['G04.152'], ['A11.251'], ['A11.284.180.165'], ['D03.132.225'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A05.360.319.114.630.535.200', 'A06.300.312.497.535.300'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conserved Molecular Superlattices in a Series of Homologous Synthetic Mycobacterial Cell-Wall Lipids Forming Interdigitated Bilayers. | Synthetic analogues of the cell-wall lipid monomycoloyl glycerol (MMG) are promising as next-generation vaccine adjuvants. In the present study, the thermotropic phase behavior of an array of synthetic MMG analogues was examined by using simultaneous small- and wide-angle X-ray scattering under excess water conditions.... | ['Artificial Cells', 'Bacterial Vaccines', 'Buffers', 'Cell Wall', 'Electrons', 'Lipid Bilayers', 'Molecular Conformation', 'Monoglycerides', 'Mycobacterium', 'Phase Transition', 'Phosphatidylcholines', 'Scattering, Radiation', 'Stereoisomerism', 'Temperature', 'Thermodynamics', 'X-Ray Diffraction'] | 27,934,510 | [['J01.637.051.479.258', 'J01.637.087.500.254'], ['D20.215.894.135'], ['D27.720.470.280'], ['A11.284.183'], ['G01.249.335', 'G01.358.500.750'], ['D10.570.510', 'J01.637.087.500.510'], ['G02.111.570.820'], ['D10.351.676'], ['B03.510.024.962.500', 'B03.510.460.400.410.552.552'], ['G01.645', 'G02.734'], ['D10.570.755.375.... | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The IS1111 insertion sequence used for detection of Coxiella burnetii is widespread in Coxiella-like endosymbionts of ticks. | Coxiella is a genus of obligate intracellular bacteria engaged in a variety of interactions with eukaryotes. The type species, Coxiella burnetii, infects several vertebrate species, including humans, and is the causative agent of Q fever. Multiple copies of a specific transposable element, the insertion sequence IS1111... | ['Amino Acid Sequence', 'Animals', 'Argasidae', 'Coxiella', 'Coxiella burnetii', 'Coxiellaceae', 'DNA Transposable Elements', 'DNA, Bacterial', 'Genome, Bacterial', 'Humans', 'Ixodidae', 'Q Fever', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Symbiosis'] | 26,269,380 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.500.131.166.132.832.100'], ['B03.440.400.425.297.150', 'B03.660.250.132.150'], ['B03.440.400.425.297.150.100', 'B03.660.250.132.150.100'], ['B03.440.400.425.297', 'B03.660.250.132'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Long-term storage of compound solutions for high-throughput screening by using a novel 1536-well microplate. | This report describes the features and the performance of a new and significantly improved 1536-well microplate design. The design allows for simple, automation-friendly, and cost-effective storage of compound solutions for high-throughput screening. The plate design is based on Society for Biomolecular Sciences standa... | ['Automation', 'Combinatorial Chemistry Techniques', 'Drug Design', 'Drug Storage', 'Miniaturization', 'Solvents', 'Water'] | 19,487,771 | [['J01.897.104'], ['E05.197.312', 'J01.897.836.249.249'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E05.916.350'], ['J01.897.520'], ['D27.720.844'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Endogenous axoplasmic proteins and proteins containing nuclear localization signal sequences use the retrograde axonal transport/nuclear import pathway in Aplysia neurons. | When the nuclear localization signal peptide (sp) of the SV 40 large T antigen was coupled to human serum albumin (HSA), rhodaminated (r), and microinjected into axons of Aplysia neurons in vitro, the rHSA-sp was conveyed through the axon to the cell body and then into the nucleus (Ambron et al., 1992). But since rHSA-... | ['Amino Acid Sequence', 'Animals', 'Antigens, Polyomavirus Transforming', 'Aplysia', 'Axonal Transport', 'Blotting, Western', 'Cell Nucleus', 'Electrophoresis, Polyacrylamide Gel', 'Ganglia', 'Histones', 'Horseradish Peroxidase', 'Humans', 'In Vitro Techniques', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Nerv... | 7,690,069 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.624.664.520.090', 'D12.776.964.700.090', 'D23.050.285.062.090', 'D23.050.327.062.090'], ['B01.050.500.644.400.060'], ['G03.143.355.040', 'G04.392.040', 'G11.561.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.60... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations. | The catalytic subunit of protein kinase A (PKA-C) is subject to several post- or cotranslational modifications that regulate its activity both spatially and temporally. Among those, N-myristoylation increases the kinase affinity for membranes and might also be implicated in substrate recognition and allosteric regulati... | ['Catalytic Domain', 'Cyclic AMP-Dependent Protein Kinases', 'Molecular Dynamics Simulation', 'Myristic Acid', 'Protein Conformation', 'Protein Structure, Secondary'] | 23,205,665 | [['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D10.251.640.630'], ['G02.111.570.820.709'], ['G02.111.570.820.709.600']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The induction of systemic and mucosal immune responses to antigen-adjuvant compositions administered into the skin: alterations in the migratory properties of dendritic cells appears to be important for stimulating mucosal immunity. | The properties of various vaccine-adjuvant formulations that are capable of inducing both systemic and common mucosal immunity subsequent to their intradermal administration are described. Effective mucosal adjuvants, including bacterial toxins, chemical enhancers of cyclic AMP, and the active form of vitamin D3, all s... | ['Administration, Topical', 'Animals', 'Bacterial Toxins', 'Cell Movement', 'Cholecalciferol', 'Cholera Toxin', 'Colforsin', 'Cyclic AMP', 'Dendritic Cells', 'Enterotoxins', 'Enzyme-Linked Immunosorbent Assay', 'Escherichia coli Proteins', 'Feces', 'Female', 'Immunity, Mucosal', 'Immunoglobulin A', 'Immunoglobulin G', ... | 10,781,863 | [['E02.319.267.120'], ['B01.050'], ['D23.946.123'], ['G04.198', 'G07.568.500.180'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['D08.811.913.400.725.115.180', 'D23.946.123.194', 'D23.946.330.150'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pathology of heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon Salmo salar. | This is the first description of heart and skeletal muscle inflammation (HSMI), a novel disease affecting farmed Atlantic salmon Salmo salar in Norway. HSMI was first diagnosed in 1999, and there has since been a yearly increase in the number of recorded outbreaks. Atlantic salmon are commonly affected 5 to 9 mo after ... | ['Animals', 'Aquaculture', 'Disease Outbreaks', 'Fish Diseases', 'Fluorescent Antibody Technique, Indirect', 'Histological Techniques', 'Liver', 'Muscle, Skeletal', 'Myocarditis', 'Myocardium', 'Myositis', 'Norway', 'Salmo salar'] | 15,264,718 | [['B01.050'], ['J01.040.168'], ['N06.850.290'], ['C22.362'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.583.375.310'], ['E01.370.225.750', 'E05.200.750'], ['A03.620'], ['A02.633.567', 'A10.690.552.500'], ['C14.280.238.625... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
A novel activation pathway for mature thymocytes. Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation. | Prior studies have shown that thymocytes, unlike peripheral T cells, do not proliferate in response to mitogenic combinations of anti-CD2 mAbs. The present study demonstrated that stimulation by a mitogenic anti-CD2 combination (9-1 plus 9.6) with anti-CD28 induced vigorous thymocyte proliferation in the absence of exo... | ['Antibodies, Monoclonal', 'Antigens, Differentiation, T-Lymphocyte', 'Blotting, Northern', 'Cells, Cultured', 'Child', 'Child, Preschool', 'Fluorescent Antibody Technique', 'Gene Expression Regulation', 'Humans', 'Infant', 'Infant, Newborn', 'Interleukin-2', 'Lymphocyte Activation', 'RNA, Messenger', 'Receptors, Inter... | 3,049,912 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.894', 'D23.101.100.894'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A11.251'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.50... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An epidemiological case-control study of breast cancer and alcohol consumption. | A case-control study of breast cancer and alcohol consumption was conducted with 1617 patients diagnosed with a primary cancer of the breast between 1982 and 1984 in 18 New York State counties. For each case, one control, matched for year of birth and county of residence, was selected from the driver's license files of... | ['Adult', 'Age Factors', 'Aged', 'Alcohol Drinking', 'Breast Neoplasms', 'Case-Control Studies', 'Female', 'Humans', 'Middle Aged', 'New York', 'Odds Ratio', 'Risk Factors'] | 2,262,245 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F01.145.317.269'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.107.567.875.075.437', 'Z01.10... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Staining of Plasmodium yoelii-infected mouse erythrocytes with the fluorescent dye rhodamine 123. | The cationic permeant fluorescent dye rhodamine 123 (R123) was used to stain Plasmodium yoelii-infected mouse erythrocytes. Fluorescence microscopic observations demonstrated that the parasite, but not the matrix of the infected erythrocyte, accumulated the dye. Differences in fluorescence intensity could not be found ... | ['Animals', 'Carbonyl Cyanide m-Chlorophenyl Hydrazone', 'Cell Nucleus', 'Dicyclohexylcarbodiimide', 'Erythrocytes', 'Fluorescent Dyes', 'Membrane Potentials', 'Mice', 'Microscopy, Fluorescence', 'Mitochondria', 'Plasmodium', 'Rhodamine 123', 'Rhodamines', 'Staining and Labeling', 'Xanthenes'] | 6,198,515 | [['B01.050'], ['D02.442.288.200', 'D02.626.260'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D02.491.203.385'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['B01.050.150.900.649.313.992.635.505.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First-principles, structure-based transdermal transport model to evaluate lipid partition and diffusion coefficients of hydrophobic permeants solely from stratum corneum permeation experiments. | To account for the effect of branched, parallel transport pathways in the intercellular domain of the stratum corneum (SC) on the passive transdermal transport of hydrophobic permeants, we have developed, from first-principles, a new theoretical model-the Two-Tortuosity Model. This new model requires two tortuosity fac... | ['Administration, Cutaneous', 'Computer Simulation', 'Diffusion', 'Diffusion Chambers, Culture', 'Finite Element Analysis', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'In Vitro Techniques', 'Membrane Lipids', 'Models, Biological', 'Molecular Structure', 'Naphthols', 'Permeability', 'Pharmaceutical Preparatio... | 17,887,175 | [['E02.319.267.120.060'], ['L01.224.160'], ['G01.202', 'G02.196'], ['E07.241'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['E05.481'], ['D10.570'], ['E05.599.395'], ['G02.111.570', 'G02.466'], ['D02.455.426.559.847.638.638', 'D04.615.638.638'], ['G02.723'], ['D26'], ['E05.318.740.750', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Critical Role of an MHC Class I-Like/Innate-Like T Cell Immune Surveillance System in Host Defense against Ranavirus (Frog Virus 3) Infection. | Besides the central role of classical Major Histocompatibility Complex (MHC) class Ia-restricted conventional Cluster of Differentiation 8 (CD8) T cells in antiviral host immune response, the amphibian Xenopus laevis critically rely on MHC class I-like (mhc1b10.1.L or XNC10)-restricted innate-like (i)T cells (iVá6 T ce... | ['Animals', 'Cytokines', 'DNA Virus Infections', 'Immunity, Innate', 'Immunologic Factors', 'Interferons', 'Ranavirus', 'T-Lymphocytes', 'Xenopus laevis'] | 30,959,883 | [['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C01.925.256'], ['G12.450.564'], ['D27.505.696.477'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['B04.280.410.700'], ['A11.118.637.555.567.569', 'A15.145.229.637.555.567.569', 'A15.382.490.555.567.569'], ['B01.050.150.900.090... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fictive motor activity in rat after 14 days of hindlimb unloading. | The goal of the present study was to examine the effects of chronic hindlimb unloading on fictive motor patterns which can be developed in hindlimb nerves of adult rats. The animals were divided into two groups. The first group was submitted to hindlimb unloading for 2 weeks by tail suspension. The second group served ... | ['Action Potentials', 'Adaptation, Physiological', 'Afferent Pathways', 'Animals', 'Central Nervous System', 'Efferent Pathways', 'Gait', 'Hindlimb', 'Kinesthesis', 'Male', 'Motor Neurons', 'Muscle Contraction', 'Muscle, Skeletal', 'Nerve Net', 'Neuronal Plasticity', 'Periodicity', 'Peripheral Nerves', 'Rats', 'Rats, W... | 11,482,841 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['G07.025', 'G16.012.500'], ['A08.612.220'], ['B01.050'], ['A08.186'], ['A08.612.380'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['A13.473'], ['F02.830.816.541.504', 'G11.561.790.541.587'], ['A08.675.655.500', 'A11.671.655.500'], ['G11.427.494'], ['A02.633.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of porcine glycogen synthase kinase 3á (GSK-3á) gene and its association with carcass traits. | GSK-3 plays an important role on numerous cellular processes involved in the regulation of embryonic development, protein synthesis, glycogen metabolism, inflammatory, mitosis and apoptosis. In this study, we obtained the cDNA and promoter sequences of the porcine GSK-3á gene, analyzed its genomic organization and mapp... | ['Abdominal Fat', 'Adiposity', 'Animals', 'Back', 'Buttocks', 'Chromosome Mapping', 'Evolution, Molecular', 'Female', 'Gene Frequency', 'Genetic Association Studies', 'Genotype', 'Glycogen Synthase Kinase 3', 'Molecular Sequence Data', 'Muscle, Skeletal', 'Organ Specificity', 'Phylogeny', 'Polymorphism, Restriction Fra... | 23,358,925 | [['A10.165.114.830.500'], ['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['B01.050'], ['A01.923.176'], ['A01.378.610.100'], ['E05.393.183'], ['G05.045.250', 'G16.075.250'], ['G05.330'], ['E05.393.385'], ['G05.380'], ['D05.500.117.875', 'D08.811.913.696.620.682.700.429.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Information processing and movement optimization during development: kinematics of cyclical pointing in 5- to 11-year-old children. | The authors studied the development of movement control in speed-accuracy tradeoff conditions in children aged 5-11 years and in adults performing cyclical pointings. Twelve difficulty levels (IDs), ranging from 2 to 6.58 bits, were defined (P. M. Fitts, 1954). Peak and time to peak velocity, acceleration, and decelera... | ['Acceleration', 'Age Factors', 'Biomechanical Phenomena', 'Child', 'Child Development', 'Child, Preschool', 'Female', 'Hand', 'Humans', 'Male', 'Motion Perception', 'Motor Skills', 'Movement', 'Periodicity', 'Practice, Psychological', 'Space Perception', 'Time Factors'] | 12,711,588 | [['G01.482.107'], ['N05.715.350.075', 'N06.850.490.250'], ['G01.154.090', 'G01.374.089'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.932.567'], ['F02.808.260'], ['G07.568', 'G11.427.410'], ['G01.910.645', ... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Follow-up of children with shunted hydrocephalus. | In order to determine if routine yearly evaluations of children with shunted hydrocephalus were likely to diagnose shunt malfunction, we reviewed the medical records of the last 100 children who had such routine evaluations. Only 4 children had symptoms that were potentially referable to malfunction; none were subseque... | ['Child', 'Equipment Failure', 'Female', 'Follow-Up Studies', 'Humans', 'Hydrocephalus', 'Male', 'Reoperation', 'Ventriculoperitoneal Shunt'] | 9,577,975 | [['M01.060.406'], ['E05.325'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602'], ['E04.690'], ['E04.035.188.850', 'E04.525.170.850']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
How does ptosis affect satisfaction after immediate reconstruction plus contralateral mammaplasty? | Breast reconstruction can reduce psychologic distress without interfering with adjuvant treatment. The study was conducted to determine how ptosis affects satisfaction after immediate partial breast reconstruction with local flaps and symmetrization of the contralateral breast. Twenty patients, with estimated breast vo... | ['Adult', 'Brazil', 'Breast Implantation', 'Breast Implants', 'Breast Neoplasms', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Mammaplasty', 'Mastectomy', 'Middle Aged', 'Patient Satisfaction', 'Retrospective Studies', 'Surgical Flaps', 'Treatment Outcome'] | 20,661,128 | [['M01.060.116'], ['Z01.107.757.176'], ['E02.218.565.210', 'E04.650.210', 'E04.680.500.210'], ['E07.695.140'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Influence of cartilage conformation on its equilibrium water partition. | The spatial and bulk water equilibrium partition and fluid content were determined for normal adult bovine articular cartilage as a function of pH, temperature, and geometric confinement. Water partition averaged 60 +/- 7% at neutral pH and 37 degrees C and increased with decreasing pH and increasing temperature withou... | ['Analysis of Variance', 'Animals', 'Body Water', 'Cartilage, Articular', 'Cattle', 'Hydrogen-Ion Concentration', 'Knee Joint', 'Temperature', 'Thermodynamics', 'Water-Electrolyte Balance'] | 4,067,706 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A12.207.200'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.500.380.271'], ['G02.300'], ['A02.835.583.475'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Differential expression of plexin-A subfamily members in the mouse nervous system. | Plexins comprise a family of transmembrane proteins (the plexin family) which are expressed in nervous tissues. Some plexins have been shown to interact directly with secreted or transmembrane semaphorins, while plexins belonging to the A subfamily are suggested to make complexes with other membrane proteins, neuropili... | ['Animals', 'Antibodies, Monoclonal', 'Auditory Pathways', 'Ear, Inner', 'Ganglia', 'Gene Expression Regulation, Developmental', 'Hippocampus', 'Immunohistochemistry', 'In Situ Hybridization', 'Mice', 'Mice, Inbred ICR', 'Neocortex', 'Nerve Tissue Proteins', 'Nervous System', 'Neuroglia', 'Neurons', 'Olfactory Pathways... | 11,241,833 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A08.612.220.110'], ['A09.246.300'], ['A08.340'], ['G05.308.310'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Recurrent gestational trophoblastic disease following in-vitro fertilization. | Recurrence of gestational trophoblastic disease (GTD) following two attempts at in-vitro fertilization (IVF)/embryo transfer is reported in a childless couple after 17 years of unsuccessful trials of ovulation induction. The diagnosis of bilateral tubal obstruction was finally established, indicating IVF treatment. Aft... | ['Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Chorionic Gonadotropin', 'Chorionic Gonadotropin, beta Subunit, Human', 'Cyclophosphamide', 'Dactinomycin', 'Embryo Transfer', 'Etoposide', 'Female', 'Fertilization in Vitro', 'Humans', 'Infertility, Female', 'Methotrexate', 'Peptide Fragments', 'Pregnancy', ... | 7,532,652 | [['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D06.472.699.322.326.125', 'D06.472.699.649.367.125', 'D12.644.548.726.367.125', 'D12.776.780.400.125', 'D23.101.140.325', 'D23.101.175'], ['D02.455.526... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Interleukin-6 and Type-I Collagen Production by Systemic Sclerosis Fibroblasts Are Differentially Regulated by Interleukin-17A in the Presence of Transforming Growth Factor-Beta 1. | Functional cytokine networks have been poorly characterized in systemic sclerosis (SSc). While interleukin-17A (IL-17A) is increased in SSc skin and other organs, its role is still debated, particularly considering fibrogenesis. We uncover here a dual function of IL-17A in the presence of transforming growth factor-â 1... | ['Adult', 'Aged', 'Cells, Cultured', 'Collagen Type I', 'Female', 'Fibroblasts', 'Fibrosis', 'Gene Expression Regulation', 'Humans', 'Interleukin-17', 'Interleukin-6', 'MAP Kinase Signaling System', 'Male', 'Middle Aged', 'NF-kappa B', 'Scleroderma, Systemic', 'Skin', 'Transforming Growth Factor beta1'] | 30,150,989 | [['M01.060.116'], ['M01.060.116.100'], ['A11.251'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['A11.329.228'], ['C23.550.355'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.517', 'D12.776.467.374.465.517', 'D23.529.374.465.517'], ['D12.644.276.374.465.224', 'D12.... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of different staging methods for COPD in predicting outcomes. | Chronic obstructive pulmonary disease (COPD) is commonly staged according to the percentage of predicted forced expiratory volume in 1 s (FEV1 % pred), but other methods have been proposed. In this study we compared the performance of seven staging methods in predicting outcomes.We retrospectively studied 296 COPD outp... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Forced Expiratory Volume', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Outcome Assessment, Health Care', 'Pulmonary Disease, Chronic Obstructive', 'Pulmonary Medicine', 'Regression Analysis', 'Retrospective Studies', 'Spirometry',... | 29,439,022 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
[Differences in the protein kinase C activity in CHO-K1 cells and in clone cells of this line resistant to ethidium bromide]. | Protein kinase C (PK C) activity in cells of two ethidium bromide (EB) resistant clones with different proliferating rates, derived from CHO-K1 cell line, was assayed. After selection in the presence of 1 mkg/ml EB cells of isolated clones acquired cross-resistance also to some unrelated drugs of different structure. I... | ['Animals', 'CHO Cells', 'Cell Division', 'Cell Line, Transformed', 'Clone Cells', 'Cricetinae', 'Cricetulus', 'Dose-Response Relationship, Drug', 'Drug Resistance', 'Ethidium', 'Female', 'Protein Kinase C'] | 8,266,573 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210.172'], ['A11.251.353'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.984'], ['D... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-angiogenic effect of the seed extract of Benincasa hispida Cogniaux. | Benincasa hispida in Korea was used mainly diabetes and diuresis diseases. This study was carried out to evaluate anti-angiogenic effect of the seed extract of Benincasa hispida Cogniaux. Basic fibroblast growth factor (bFGF) is a potent angiogenic factor found in various tumors. In this study, we found that the seed e... | ['Angiogenesis Inhibitors', 'Animals', 'Cells, Cultured', 'Cucurbitaceae', 'Endothelium, Vascular', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Plant Extracts', 'Seeds'] | 15,740,888 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['B01.050'], ['A11.251'], ['B01.650.940.800.575.912.250.300'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.15... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Harnessing longitudinal information to identify genetic variation in tolerance of pigs to Porcine Reproductive and Respiratory Syndrome virus infection. | BACKGROUND: High resistance (the ability of the host to reduce pathogen load) and tolerance (the ability to maintain high performance at a given pathogen load) are two desirable host traits for producing animals that are resilient to infections. For Porcine Reproductive and Respiratory Syndrome (PRRS), one of the most ... | ['Animals', 'Disease Resistance', 'Polymorphism, Single Nucleotide', 'Porcine Reproductive and Respiratory Syndrome', 'Swine'] | 30,355,341 | [['B01.050'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['G05.365.795.598'], ['C01.925.782.600.100.700', 'C22.905.700'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optimal allocation of HIV resources among geographical regions. | BACKGROUND: Health resources are limited, which means spending should be focused on the people, places and programs that matter most. Choosing the mix of programs to maximize a health outcome is termed allocative efficiency. Here, we extend the methodology of allocative efficiency to answer the question of how resource... | ['Algorithms', 'Decision Making', 'Delivery of Health Care', 'Financing, Organized', 'HIV Infections', 'Health Care Costs', 'Health Resources', 'Humans', 'Quality-Adjusted Life Years', 'Resource Allocation', 'Spatial Analysis', 'Ukraine'] | 31,718,603 | [['G17.035', 'L01.224.050'], ['F02.463.785.373'], ['N04.590.374', 'N05.300'], ['N03.219.521'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['N03.219.151.400', 'N05.300.375'], ['N03.349.340', 'N05.300.420'], ['B01.050.150.900.649.313.988.400... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Pharmacokinetic modeling and [?²³]5-IA-85380 single photon emission computed tomography imaging in baboons: optimization of dosing regimen for ABT-089. | Neuronal acetylcholine nicotinic receptors (nAChRs) are targets for the development of novel treatments of brain diseases. However, adverse effects (for example, emesis or nausea) associated with high drug maximal exposures or C(max) at nAChRs often hinder the advancement of experimental compounds in clinical trials. T... | ['Animals', 'Azetidines', 'Brain', 'Dose-Response Relationship, Drug', 'Female', 'Models, Biological', 'Papio', 'Papio anubis', 'Pyridines', 'Pyrrolidines', 'Tomography, Emission-Computed, Single-Photon'] | 21,172,907 | [['B01.050'], ['D03.383.082.301'], ['A08.186.211'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.599.395'], ['B01.050.150.900.649.313.988.400.112.199.120.610'], ['B01.050.150.900.649.313.988.400.112.199.120.610.050'], ['D03.383.725'], ['D03.383.773'], ['E01.370.350.350.800.800', 'E01.370.350.600.350.800.800', 'E01.370... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling. | A-kinase anchor protein 121 (AKAP121) and its spliced isoform AKAP84 anchor protein kinase A (PKA) to the outer membrane of mitochondria, focusing and enhancing cyclic AMP signal transduction to the organelle. We find that AKAP121/84 also binds PTPD1, a src-associated protein tyrosine phosphatase. A signaling complex c... | ['A Kinase Anchor Proteins', 'Adaptor Proteins, Signal Transducing', 'Carrier Proteins', 'Cyclic AMP-Dependent Protein Kinases', 'Epidermal Growth Factor', 'ErbB Receptors', 'Humans', 'Mitochondria', 'Phosphorylation', 'Protein Isoforms', 'Protein Tyrosine Phosphatases', 'Protein Tyrosine Phosphatases, Non-Receptor', '... | 15,143,158 | [['D12.644.360.024.065', 'D12.776.157.057.003', 'D12.776.476.024.069'], ['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.776.157'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improved survival of vitrified porcine embryos after partial delipation through chemically stimulated lipolysis and inhibition of apoptosis. | Mechanical removal of intracellular lipids has been the most effective approach to increase the cryosurvival of porcine embryos. In this experiment, we tested the hypotheses that the cryosurvival of porcine embryos can be improved after partial delipation through chemically stimulated lipolysis and that the survival ca... | ['Amino Acid Chloromethyl Ketones', 'Animals', 'Apoptosis', 'Blastocyst', 'Cell Survival', 'Colforsin', 'Cryopreservation', 'Cysteine Proteinase Inhibitors', 'Embryo Culture Techniques', 'Lipolysis', 'Swine'] | 16,870,242 | [['D12.125.065'], ['B01.050'], ['G04.146.954.035'], ['A16.254.500'], ['G04.346'], ['D02.455.849.291.300'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['D27.505.519.389.745.325'], ['E05.481.500.468'], ['G02.111.534',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outcome of open Tenckhoff catheter insertions: 5 years experience in a major tertiary centre in central Saudi Arabia. | BACKGROUND: Continuous ambulatory peritoneal dialysis (CAPD) has become a popular and established form of renal replacement therapy in patients with end-stage renal disease (ESRD). The objective of this study was to analyse the outcome of open Tenckhoff catheter insertions in patients with ESRD in term of catheter rela... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Catheter-Related Infections', 'Catheterization', 'Catheters, Indwelling', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Peritoneal Dialysis, Continuous Ambulatory', 'Retrospective Studies', 'Saudi Arabia', 'Young Adult'] | 25,226,729 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.195'], ['E02.148', 'E05.157'], ['E07.132.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['E02.760.106.500', 'E02.870.300.650.500', 'E02.912.800... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of glycerol on human adipose tissue triglyceride lipase activity. | Glycerol fully protects the human adipose tissue triglyceride lipase against the denaturing effects of high and low temperatures. Under such protection, storage of crude preparations at -10 degrees C or incubation at 50 degrees C resulted in a 1.5-3-fold increase of the measured lipase activity. This increase was shown... | ['Adipose Tissue', 'Carbon Isotopes', 'Chromatography', 'Chromatography, Thin Layer', 'Cold Temperature', 'Drug Stability', 'Glycerol', 'Hot Temperature', 'Humans', 'Hydrogen-Ion Concentration', 'Kinetics', 'Lipase', 'Methods', 'Protein Denaturation', 'Time Factors', 'Triglycerides', 'Triolein', 'Tritium'] | 4,729,976 | [['A10.165.114'], ['D01.268.150.075', 'D01.496.123'], ['E05.196.181'], ['E05.196.181.400.537'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E05.916.330'], ['D02.033.800.875.500', 'D09.853.875.500'], ['G01.906.595.543', 'G16.5... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Claudin-based permeability barriers in taste buds. | Tight junctions operate as semipermeable barriers in epithelial tissue, separating the apical from the basolateral sides of the cells. Membrane proteins of the claudin family represent the major tight junction constituents, and some reinforce permeability barriers, whereas others create pores based on solute size and i... | ['Animals', 'Cell Communication', 'Cell Membrane', 'Cell Membrane Permeability', 'Claudin-4', 'Claudins', 'Diffusion', 'Humans', 'Immunohistochemistry', 'Membrane Proteins', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Taste', 'Taste Buds', 'Tight Junctions'] | 17,447,253 | [['B01.050'], ['G04.085'], ['A11.284.149'], ['G03.143.335', 'G04.175'], ['D12.776.543.940.200.400'], ['D12.776.543.940.200'], ['G01.202', 'G02.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Transfer of paralytic shellfish toxins via marine food chains: a simulated experiment. | OBJECTIVE: To study the transfer of paralytic shellfish toxins (PST) using four simulated marine food chains: dinoflagellate Alexandrium tamarense --> Artemia Artemia salina --> Mysid shrimp Neomysis awatschensis; A. tamarense --> N. awatschensis; A. tamarense --> A. salina --> Perch Lateolabrax japonicus; and A. tamar... | ['Animals', 'Artemia', 'Cell Count', 'Chlorophyll', 'Chlorophyll A', 'Eukaryota', 'Feeding Behavior', 'Fishes', 'Food Chain', 'Hydrolysis', 'Marine Toxins', 'Mice', 'Models, Biological', 'Mollusca', 'Paralysis'] | 17,672,215 | [['B01.050'], ['B01.050.500.131.365.060.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D03.383.129.578.840.374.140', 'D03.633.400.909.374.140', 'D04.345.783.374.140'], ['B01'], ['F01.145.113.547', 'F01.145.407', 'G07.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Development of a new version of the Liverpool Malaria Model. II. Calibration and validation for West Africa. | BACKGROUND: In the first part of this study, an extensive literature survey led to the construction of a new version of the Liverpool Malaria Model (LMM). A new set of parameter settings was provided and a new development of the mathematical formulation of important processes related to the vector population was perfor... | ['Africa, Western', 'Animals', 'Climate', 'Female', 'Humans', 'Insect Vectors', 'Malaria', 'Models, Theoretical'] | 21,410,939 | [['Z01.058.290.190'], ['B01.050'], ['G16.500.275.071', 'N06.230.300.100.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['C01.610.752.530', 'C01.920.875'], ['E05.599']] | ['Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Enzyme transfer of phosphate from adenosine triphosphate to protein-bound serine residues in cerebral microsomes. | 1. Microsomes from guinea-pig brain grey matter were incubated with [(32)P]ATP at 3mm concentration and the phosphate bound to the acid-washed, lipid-free residue was determined. 2. The binding process was Mg(2+)-dependent and resulted in the transfer of about 1-2 mmumoles of phosphate/mg. of protein/min. Under the con... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Animals', 'Cerebral Cortex', 'Chloromercuribenzoates', 'Guinea Pigs', 'In Vitro Techniques', 'Microsomes', 'Nerve Tissue Proteins', 'Phosphates', 'Phosphorus Isotopes', 'Protein Binding', 'Serine'] | 4,226,015 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A08.186.211.200.885.287.500'], ['D02.241.223.100.200.311', 'D02.241.223.100.500.261', 'D02.455.426.559.389.127.250.311', 'D02.455.426.559.389.127.500.261', 'D02.691.750.740.644.261'], ['B01.050.150.90... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Testing for mechanistic interactions in long-term follow-up studies. | In follow-up studies, interactions are often assessed by including a cross-product term in a (multiplicative) Cox model. However, epidemiologists/clinicians often misinterpret a significant multiplicative interaction as a genuine mechanistic interaction. Though indices specific to mechanistic interactions have been pro... | ['Algorithms', 'Models, Theoretical'] | 25,811,982 | [['G17.035', 'L01.224.050'], ['E05.599']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Amygdala afferents monosynaptically innervate corticospinal neurons in rat medial prefrontal cortex. | The amygdala provides the medial prefrontal cortex (mPFC; areas 25, 32, and 24b) with salient emotional information. This study investigated the synaptic connectivity of identified amygdalocortical boutons (ACBs; labeled anterogradely following injections of Phaseolus vulgaris leucoagglutinin into the basolateral nucle... | ['Afferent Pathways', 'Amygdala', 'Animals', 'Male', 'Neuroanatomical Tract-Tracing Techniques', 'Neurons, Afferent', 'Prefrontal Cortex', 'Presynaptic Terminals', 'Pyramidal Tracts', 'Rats', 'Rats, Sprague-Dawley', 'Synapses'] | 22,247,040 | [['A08.612.220'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['E01.370.225.500.620.670.570', 'E01.370.225.750.600.670.570', 'E05.200.500.620.670.570', 'E05.200.750.600.670.570'], ['A08.675.650', 'A11.671.650'], ['A08.186.211.200.885.287.500.270.700'], ['A08.675.542.145.750', 'A08.850.700',... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Birth order, family environment, and young adults' occupational aspirations. | Relationships were examined among birth order, family environments, and occupational aspirations for 320 21-yr.-old Australians. The results indicated that relations between birth order and aspirations were mediated by associations between the young adults' perceptions of their parents' involvement in learning and the ... | ['Adolescent', 'Adult', 'Aspirations, Psychological', 'Australia', 'Birth Order', 'Career Choice', 'Family', 'Female', 'Humans', 'Male', 'Personality Development', 'Social Environment'] | 8,559,892 | [['M01.060.057'], ['M01.060.116'], ['F01.658.100', 'F02.784.629.155'], ['Z01.639.100', 'Z01.678.100.373'], ['F01.829.263.132', 'I01.240.361.160', 'N01.224.361.160', 'N06.850.505.400.400.160'], ['F02.463.785.373.346.400'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Cloning and sequencing of a phospholipase C gene of Clostridium perfringens. | The gene encoding phospholipase C (alpha-toxin) of Clostridium perfringens was cloned into lambda gt10. The maximal size of the coding region was 1.4 kb and the minimum was 1.1 kb as determined by subcloning into the vector pBR322 and testing for activity. The nucleotide sequence of this region contained a single open ... | ['Amino Acid Sequence', 'Bacteriophage lambda', 'Base Composition', 'Base Sequence', 'Cloning, Molecular', 'Clostridium perfringens', 'Codon', 'DNA Restriction Enzymes', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Molecular Sequence Data', 'Plasmids', 'Promoter Regions, Genetic', 'Sequence Homology, Nuc... | 2,540,749 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B04.123.150.800.230', 'B04.123.205.230', 'B04.280.090.800.230'], ['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['B03.300.390.400.200.575', 'B03.353.625.375.500.575', 'B03.510.415.400.200.575'], ['D13.444.735.544.355', 'G05.360... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Performance analysis and early validation of a bi-modal ultrasound transducer. | In this paper we report on results from experiments performed on a bi-modal piezoelectric transducer used both as an active ultrasound transceiver and a passive acoustic sensor. The transducer, which has a low Q factor in order to exhibit a sufficiently broad bandwidth, will be integrated into a wearable system. In par... | ['Acoustics', 'Blood Pressure Determination', 'Equipment Design', 'Equipment Failure Analysis', 'Humans', 'Monitoring, Ambulatory', 'Pilot Projects', 'Reproducibility of Results', 'Respiratory Function Tests', 'Respiratory Mechanics', 'Sensitivity and Specificity', 'Transducers', 'Ultrasonography'] | 17,945,676 | [['H01.671.031'], ['E01.370.370.140', 'E01.370.600.100'], ['E05.320'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520.500'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']... | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Preference for flavored wheat straw by lambs conditioned with intraruminal administrations of sodium propionate. | We hypothesized that volatile fatty acids are feedback signals that condition food preferences in ruminants, and we tested two predictions based on this hypothesis: 1) low doses of propionate condition preferences for low-quality foods (Exp. 1 and 2) preferences are not caused by osmotic load (Exp. 2). In Exp. 1, lambs... | ['Animals', 'Dose-Response Relationship, Drug', 'Eating', 'Food Preferences', 'Food Technology', 'Hydrogen-Ion Concentration', 'Male', 'Osmotic Pressure', 'Propionates', 'Rumen', 'Sheep', 'Sodium Chloride', 'Taste', 'Triticum'] | 8,904,704 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.203.650.283', 'G10.261.330'], ['F01.145.407.516', 'G07.203.650.353.516'], ['J01.576.423.850'], ['G02.300'], ['G01.374.715.578', 'G02.640.249', 'G02.723.661'], ['D02.241.081.751', 'D10.251.400.706'], ['A13.869.804'], ['B01.050.150.900.649.313.500.380.791'], ['D... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Lower limb amputations and rehabilitation]. | BACKGROUND We wished to study the therapy for lower limb amputees at S?rlandet Hospital Kristiansand after restructuring of activities in 2004.MATERIAL AND METHOD All lower limb amputees hospitalised in the Department of Physical Medicine and Rehabilitation between March 2012 and July 2015 were followed up prospectivel... | ['Adult', 'Aged', 'Aged, 80 and over', 'Amputation', 'Analgesics', 'Artificial Limbs', 'Cohort Studies', 'Critical Pathways', 'Disarticulation', 'Female', 'Femur', 'Humans', 'Knee Joint', 'Male', 'Middle Aged', 'Norway', 'Patient Care Team', 'Physical Therapy Modalities', 'Prospective Studies', 'Recovery of Function', ... | 28,468,477 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.080'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['E07.695.050', 'E07.858.082.050', 'E07.858.442.050'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N04.590.233.624.625', 'N04.590.275'], ['E04.555.080... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Establishment of an allo-transplantable hamster cholangiocarcinoma cell line and its application for in vivo screening of anti-cancer drugs. | Opisthorchis viverrini (O. viverrini) is a well-known causative agent of cholangiocarcinoma (CCA) in humans. CCA is very resistant to chemotherapy and is frequently fatal. To understand the pathogenesis of CCA in humans, a rodent model was developed. However, the development of CCA in rodents is time-consuming and the ... | ['Allografts', 'Animals', 'Antineoplastic Agents', 'Berberine', 'Cell Culture Techniques', 'Cell Line, Tumor', 'Cell Transplantation', 'Cholangiocarcinoma', 'Cricetinae', 'Culture Media', 'Disease Models, Animal', 'Drug Evaluation, Preclinical', 'Male', 'Mesocricetus'] | 24,516,278 | [['A01.941.500'], ['B01.050'], ['D27.505.954.248'], ['D03.132.098.057.100', 'D03.633.400.168.100'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251.210.190', 'A11.251.860.180'], ['E02.095.147.500', 'E04.936.225'], ['C04.557.470.200.025.450'], ['B01.050.150.900.649.313.992.635.075... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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