Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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[Alclometasone dipropionate (Legederm) for the treatment of steroid-sensitive dermatoses in the elderly]. | This is a randomized single blind parallel comparison of alclometasone dipropionate cream 0.1% vs hydrocortisone butyrrate in 39 geriatric patients (greater than 60 years old) with steroid sensible skin diseases. The regimen consisted of dosing patients with two applications of the two drugs every day for 4 weeks. Foll... | ['Aged', 'Aged, 80 and over', 'Dermatologic Agents', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Methylprednisolone', 'Single-Blind Method', 'Skin Diseases'] | 2,279,745 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['D04.210.500.745.432.769.795.539'], ['E05.318.370.850', 'N05.715.360.325.730', 'N06.850.520.445.850'], ['C17.800']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MACOP-B chemotherapy for the treatment of high-grade lymphomas in patients with HIV-1 infection. | Recent studies showed that patients with non-Hodgkin's lymphoma (NHL) with human immunodeficiency virus type 1 (HIV-1) infection may benefit from an intensive chemotherapeutic regimen. We report on our experience in the treatment of NHL-associated HIV-1 infection, with excellent prognostic factors, with MACOP-B regimen... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Bleomycin', 'Cyclophosphamide', 'Doxorubicin', 'HIV-1', 'Humans', 'Leucovorin', 'Lymphoma, AIDS-Related', 'Methotrexate', 'Middle Aged', 'Prednisone', 'Prognosis', 'Remission Induction', 'Survival Rate', 'Vincristine'] | 7,683,165 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D09.400.420.110', 'D12.644.233.110'], ['D02.455.526.728.650.730.243', 'D02... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The correlation between Pax5 deletion and patients survival in Iranian children with precursor B-cell acute lymphocytic leukemia. | Despite advances in treatment, children with acute lymphoblastic leukemia (ALL) still experience drug resistance and relapse. Several gene mutations are involved in the onset of this disease and resistance to therapy. The present study examines the incidence of IKZF1, CDKN2A/B, PAX5, EBF1, ETV6, BTG1, RB1, JAK2, and Xp... | ['Adolescent', 'Antineoplastic Agents', 'Child', 'Child, Preschool', 'Cyclin-Dependent Kinase Inhibitor p15', 'Cyclin-Dependent Kinase Inhibitor p16', 'Cyclin-Dependent Kinase Inhibitor p18', 'Drug Resistance, Neoplasm', 'Female', 'Gene Deletion', 'Gene Duplication', 'Gene Expression Regulation, Leukemic', 'Humans', 'I... | 28,886,309 | [['M01.060.057'], ['D27.505.954.248'], ['M01.060.406'], ['M01.060.406.448'], ['D12.644.360.225.100', 'D12.776.167.187.100', 'D12.776.476.225.100', 'D12.776.624.776.355.100'], ['D12.644.360.225.200', 'D12.776.167.187.200', 'D12.776.476.225.200', 'D12.776.624.776.355.200'], ['D12.644.360.225.300', 'D12.776.167.187.300', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The "fashion-form" of modern society and its relationship to psychology. | In this work, we present a new way of understanding psychology, which emerges as a result of relating it to the three principles of the theory of fashion of Gilles Lipovetsky: "the principle of the ephemeral," "the principle of the marginal differentiation of individuals," and "the principle of seduction." We relate th... | ['Historiography', 'Humans', 'Models, Psychological', 'Professional Practice', 'Psychological Theory', 'Psychology', 'Psychology, Social', 'Social Conditions', 'Social Identification', 'Sociology'] | 19,476,249 | [['K01.400.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['N04.452.758'], ['F02.739'], ['F04.096.628'], ['F01.829', 'F04.096.628.829'], ['I01.880.853.450', 'N01.824.827'], ['F01.145.813.708'], ['F04.096.879.757', 'I01.880']] | ['Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Calcium-antagonist effects of norbormide on isolated perfused heart and cardiac myocytes of guinea-pig: a comparison with verapamil. | 1. Cardiac effects on norbormide and verapamil were compared in single ventricular myocytes, right atria, and Langendorff perfused hearts isolated from guinea-pigs. 2. In ventricular myocytes, norbormide 50 microM inhibited the peak calcium current (ICa) by 49.6 +/- 3.9% without altering the shape of the current-voltag... | ['Animals', 'Calcium Channel Blockers', 'Calcium Channels', 'Electrophysiology', 'Female', 'Guinea Pigs', 'Heart', 'Heart Conduction System', 'Heart Rate', 'Hemodynamics', 'In Vitro Techniques', 'Male', 'Membrane Potentials', 'Myocardial Contraction', 'Myocardium', 'Norbornanes', 'Patch-Clamp Techniques', 'Verapamil'] | 9,117,093 | [['B01.050'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.992.550'], ['A07.541'], ['A07.541.409'], ['E01.370.600.875.500', 'G09.330.380.500'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Bowen's disease of the nipple]. | The clinical and morphological features of Bowen's disease of the nipple are reported. The 51 year old patient had an eczema type change of the left nipple for over 1 year. The microscopic evaluation of the extensive segmental resection showed Bowen's disease of the nipple. Paget's disease was excluded with certainty. ... | ["Bowen's Disease", 'Breast Neoplasms', 'Carcinoma, Squamous Cell', 'Female', 'Humans', 'Middle Aged', 'Prognosis', 'Skin Neoplasms'] | 6,922,808 | [['C04.557.470.200.400.130', 'C04.557.470.700.400.130'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['C04.588.805', 'C17.800.882']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Early-life origins of schizotypal traits in adulthood. | BACKGROUND: Although schizotypal traits, such as anhedonia and aberrant perceptions, may increase the risk for schizophrenia-spectrum disorders, little is known about early-life characteristics that predict more pronounced schizotypal traits.AIMS: To examine whether birth size or several other early-life factors that h... | ['Adolescent', 'Adult', 'Birth Order', 'Birth Weight', 'Body Size', 'Cephalometry', 'Cohort Studies', 'Disease Susceptibility', 'Female', 'Finland', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Organ Size', 'Placenta', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Regression Analysis', 'Risk Factors', 'Schizoty... | 19,648,543 | [['M01.060.057'], ['M01.060.116'], ['F01.829.263.132', 'I01.240.361.160', 'N01.224.361.160', 'N06.850.505.400.400.160'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.16... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Subcellular localization of the GABA-shunt enzymes in Euglena gracilis strain Z. | Glutamate decarboxylase, gamma-aminobutyrate-alpha-ketoglutarate aminotransferase and NAD-linked and NADP-linked succinic semialdehyde dehydrogenase, all constituting the GABA (gamma-aminobutyrate)-shunt pathway of glutamate metabolism are localized in the mitochondrial matrix in a streptomycin-bleached mutant of Eugle... | ['4-Aminobutyrate Transaminase', 'Aldehyde Oxidoreductases', 'Animals', 'Carboxy-Lyases', 'Cytoplasm', 'Euglena gracilis', 'Fumarate Hydratase', 'Glutamate Decarboxylase', 'Glutamate Dehydrogenase', 'Isoenzymes', 'L-Lactate Dehydrogenase', 'Mitochondria', 'Mutation', 'Succinate Dehydrogenase', 'Transaminases'] | 119,850 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quasi-experimental study on the effectiveness of a flipped classroom for teaching adult health nursing. | AIM: The effectiveness of flipped learning as one of the teaching methods of active learning has been left unexamined in nursing majors, compared to the frequent attempts to uncover the effectiveness of it in other disciplines. The purpose of this study was to reveal the effectiveness of flipped learning pedagogy in an... | ['Adult', 'Curriculum', 'Education, Nursing', 'Educational Status', 'Female', 'Humans', 'Male', 'Problem-Based Learning', 'Students, Nursing'] | 28,834,418 | [['M01.060.116'], ['I02.158'], ['I02.358.462'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.720', 'I02.158.660', 'I02.903.565'], ['M01.848.769.685']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Preparation of tri(ethylene glycol) grafted core-shell type polymer support for solid-phase peptide synthesis. | A core-shell type polymer support for solid-phase peptide synthesis has been developed for high coupling efficiency of peptides and versatile applications such as on-bead bioassays. Although various kinds of polymer supports have been developed, they have their own drawbacks including poor accessibility of reagents and... | ['Acetylation', 'Amino Acid Sequence', 'Animals', 'Biological Assay', 'Chemistry Techniques, Synthetic', 'Fluorenes', 'Hydrophobic and Hydrophilic Interactions', 'Mice', 'NIH 3T3 Cells', 'Neuropeptide Y', 'Peptides', 'Polyethylene Glycols', 'Polymers', 'Resins, Synthetic', 'Solid-Phase Synthesis Techniques'] | 29,235,177 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.091'], ['E05.197', 'J01.897.836.249'], ['D02.455.426.559.847.389', 'D04.615.389'], ['G02.409'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.251.210.100.550', 'A11.329.228.100.550'], ['D12.644.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Investigations on the presence of viral and chlamydial antigens in cells exfoliated in the vagina of women with common and malignant gynecopathies. | A high proportion of parainfluenza, herpes, adenovirus and chlamydial antigens (10.7-36%) was detected by indirect immunofluorescence in cells exfoliated in the vagina of women with genital neoplasia and with uterine cervix ectopia and dysplasia. Much lower proportions of the same antigens were found in patients with c... | ['Antigens, Bacterial', 'Antigens, Viral', 'Chlamydia Infections', 'Female', 'Fluorescent Antibody Technique', 'Genital Diseases, Female', 'Genital Neoplasms, Female', 'Humans', 'Vaginal Smears', 'Virus Diseases'] | 7,001,731 | [['D23.050.161'], ['D23.050.327'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['C1... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Morbidity and mortality of poisonings in hospitalized patients in the German Democratic Republic]. | In evaluation of the hospital statistics a survey is given on the kinds of intoxication and their frequency, age distribution and lethality. It is elaborated the necessity of the concentration of patients with intoxications, in order to decrease the lethality. An organisation model for the GDR is designed and the autho... | ['Age Factors', 'Germany, East', 'Hospitalization', 'Humans', 'Poisoning'] | 1,224,723 | [['N05.715.350.075', 'N06.850.490.250'], ['Z01.586.338'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.723']] | ['Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Reproductive soundness is higher in chickens selected for low as compared with high antibody response. | White Leghorn chickens were selected for 36 generations for high (HAS) or low (LAS) antibody response to SRBC 5 d after an intravenous challenge. The aim of this study was to investigate possible changes in reproductive soundness resulting from that selection. Age and BW at onset of lay (first egg), along with weight o... | ['Aging', 'Animals', 'Antibodies', 'Breeding', 'Chickens', 'Erythrocytes', 'Female', 'Gene Expression Regulation', 'Male', 'Oviposition', 'Reproduction', 'Sexual Maturation', 'Sheep'] | 22,802,170 | [['G07.345.124'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G05.308'], ['G08.686.784.480'], ['G08.686.784'], ['G07.345.75... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Daily aspirin use and cancer mortality in a large US cohort. | BACKGROUND: A recent pooled analysis of randomized trials of daily aspirin for prevention of vascular events found a substantial reduction (relative risk [RR] = 0.63, 95% confidence interval [CI] = 0.49 to 0.82) in overall cancer mortality during follow-up occurring after 5 years on aspirin. However, the magnitude of t... | ['Adult', 'Aged', 'Anticarcinogenic Agents', 'Aspirin', 'Cohort Studies', 'Drug Administration Schedule', 'Female', 'Humans', 'Male', 'Medical Record Linkage', 'Middle Aged', 'Neoplasms', 'Proportional Hazards Models', 'Research Design', 'Risk', 'Surveys and Questionnaires', 'United States'] | 22,888,140 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D02.455.426.559.389.657.410.595.176'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.500', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Using the Systems-Practice Framework to Understand Food Allergen Management Practices at College Catering Operations: A Qualitative Study. | BACKGROUND: The number of individuals with food allergies or intolerances attending catered university residential colleges is increasing, and safe dining options are required to minimize the risk of allergic reactions and food-induced death.OBJECTIVE: This qualitative research study sought to advance professional know... | ['Adult', 'Anthropology, Cultural', 'Attitude of Health Personnel', 'Female', 'Focus Groups', 'Food Hypersensitivity', 'Food Services', 'Humans', 'Male', 'New Zealand', 'Nutritional Requirements', 'Qualitative Research', 'Risk Management', 'Systems Theory', 'Universities'] | 28,688,885 | [['M01.060.116'], ['I01.076.201'], ['F01.100.050', 'N05.300.100'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['C20.543.480.370'], ['J01.576.423.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.747', 'Z01.678.100.747'], ['G07.203.650.620'], ['H01.770.644.241.850'], ['N03.219... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena a... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Ophthalmologic screening in 25 consecutive geriatric psychiatric inpatient admissions. | In the aging process, people are at increasing risk of visual abnormalities such as cataracts, glaucoma, age-related macular degeneration, and other retinal defects. This holds true for geriatric psychiatric patients as well. These ophthalmic problems may increase risk of falls or increase the comorbidity from dementin... | ['Aged', 'Aged, 80 and over', 'Aging', 'Comorbidity', 'Female', 'Geriatric Assessment', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Patient Admission', 'Quality Assurance, Health Care', 'Vision Disorders', 'Vision Screening'] | 23,963,654 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['E02... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Types of basilar artery syndrome: clinicoradiologic correlation. | Twenty-two patients with ischemic stroke, as a single event, in the territory of basilar artery (BA) are reported. On the basis of the findings from computerized tomography (CT) and clinico-radiologic features, the authors propose that this heterogeneous entity--the basilar artery (BA) syndrome--can be divided into fiv... | ['Aged', 'Aged, 80 and over', 'Brain', 'Cerebral Angiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed', 'Vertebrobasilar Insufficiency'] | 8,480,914 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.186.211'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E01.370.3... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Coarse-grained simulations of proton-dependent conformational changes in lactose permease. | During lactose/H(+) symport, the Escherichia coli lactose permease (LacY) undergoes a series of global conformational transitions between inward-facing (open to cytoplasmic side) and outward-facing (open to periplasmic side) states. However, the exact local interactions and molecular mechanisms dictating those large-sc... | ['Cytoplasm', 'Electrons', 'Escherichia coli', 'Escherichia coli Proteins', 'Gene Expression', 'Glutamic Acid', 'Kinetics', 'Lactose', 'Molecular Dynamics Simulation', 'Monosaccharide Transport Proteins', 'Periplasm', 'Protein Domains', 'Protein Structure, Secondary', 'Protons', 'Symporters', 'Thermodynamics'] | 27,090,495 | [['A11.284.430.214'], ['G01.249.335', 'G01.358.500.750'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.297'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['G01.374.661', 'G02.111.490'], ['D09.698.629.305.340', 'D09.947.750.340'], ['E05.599.595.500', 'G02.111.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hot topic: investigating the risk of violative meat residues in bob veal calves fed colostrum from cows treated at dry-off with cephapirin benzathine. | The objective was to conduct a study to investigate if violative meat residues are detected in very young bob veal calves that are fed first-milking colostrum harvested from cows that were dry treated, on-label, with cephapirin benzathine. First-milking colostrum was collected from cows that were given intramammary tre... | ['Animals', 'Animals, Newborn', 'Anti-Bacterial Agents', 'Cattle', 'Cephapirin', 'Colostrum', 'Diet', 'Drug Residues', 'Ethylenediamines', 'Female', 'Food Contamination', 'Kidney', 'Mammary Glands, Animal', 'Meat'] | 23,415,519 | [['B01.050'], ['B01.050.050.282'], ['D27.505.954.122.085'], ['B01.050.150.900.649.313.500.380.271'], ['D02.065.589.099.249.190.230', 'D02.886.665.074.190.230', 'D03.633.100.300.249.190.230'], ['A12.200.194'], ['G07.203.650.240'], ['N06.850.460.200.250'], ['D02.092.782.258.368'], ['J01.576.423.850.730.500.249', 'N06.850... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of captivity on glucose tolerance in dogs. | Captivity decreased tolerance to glucose and increased blood serotonin levels in 6 normal dogs investigated. Return to freedom brought normalization in the glucose tolerance test and reverted blood serotonin to control levels. | ['Animals', 'Blood Glucose', 'Dogs', 'Glucose Tolerance Test', 'Humans', 'Restraint, Physical', 'Serotonin', 'Stress, Psychological'] | 573,210 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence, correlates, and temporal trends in antiarrhythmic drug use at discharge after implantable cardioverter defibrillator placement (from the National Cardiovascular Data Registry [NCDR]). | Patients with implantable cardioverter defibrillators (ICDs) can require antiarrhythmic drugs to manage arrhythmias and prevent device shocks. We sought to determine the prevalence, clinical correlates, and institutional variation in the use of antiarrhythmic drugs over time after ICD implantation. From the ICD Registr... | ['Aged', 'Aged, 80 and over', 'Anti-Arrhythmia Agents', 'Arrhythmias, Cardiac', 'Death, Sudden, Cardiac', 'Defibrillators, Implantable', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Patient Discharge', 'Prevalence', 'Registries', 'Retrospective Studies', 'United States'] | 24,216,126 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.411.097'], ['C14.280.067', 'C23.550.073'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis. | We recently found that integrin ávâ3 binds to fibroblast growth factor (FGF)-ávâ31 (FGF1), and that the integrin-binding defective FGF1 mutant (Arg-50 to glutamic acid, R50E) is defective in signalling and antagonistic to FGF1 signalling. R50E suppressed angiogenesis and tumour growth, suggesting that R50E has potentia... | ['Amino Acids', 'Animals', 'Binding Sites', 'Cells, Cultured', 'Fibroblast Growth Factor 2', 'Humans', 'Integrin alphaVbeta3', 'K562 Cells', 'Kinetics', 'Mice', 'Models, Molecular', 'Mutation, Missense', 'NIH 3T3 Cells', 'Neovascularization, Physiologic', 'Protein Binding', 'Protein Domains', 'Rats', 'Signal Transducti... | 28,302,677 | [['D12.125'], ['B01.050'], ['G02.111.570.120'], ['A11.251'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.625.439', 'D12.776.543.550.625.439', 'D12.776.543.750.705.408.460.870.500', 'D12.776.543.750.705.675.541'], ['A11.251.210.190... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protective effect of hochuekkito, a Kampo prescription, against ultraviolet B irradiation-induced skin damage in hairless mice. | A Kampo prescriptions, hochuekkito (HET) has been utilized for treating functional conditions such as general fatigue, compromised state and gastrointestinal motility disorder. Recently, HET has attracted the attention of dermatologists because of its clinically positive effects in atopic dermatitis (AD) treatment. To ... | ['Animals', 'Drug Evaluation, Preclinical', 'Drugs, Chinese Herbal', 'Male', 'Medicine, Kampo', 'Mice', 'Mice, Hairless', 'Oxidative Stress', 'Plant Extracts', 'Skin Aging', 'Skin Diseases', 'Ultraviolet Rays', 'Water Loss, Insensible'] | 23,294,358 | [['B01.050'], ['E05.290.750', 'E05.337.550'], ['D20.215.784.500.350', 'D26.335'], ['E02.190.488.585.600', 'I01.076.201.450.654.558.600'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.200', 'B01.050.150.900.649.313.992.635.505.500.400.200', 'B01.050.150.900.649.313.992.635.505.500.550.230'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
MicroRNA-200c exacerbates the ischemia/reperfusion injury of heart through targeting the glutaminase (GLS)-mediated glutamine metabolism. | OBJECTIVE: Cardiac ischemia and reperfusion, the common pathophysiological processes during cardiovascular surgery, are followed by oxidative stresses during the restoration of blood flow to the tissue, known as ischemia/reperfusion (IR) injury. microRNAs (miRNAs) are a group of endogenous, short and noncoding RNAs tha... | ['Animals', 'Glutaminase', 'Glutamine', 'Male', 'MicroRNAs', 'Myocardial Reperfusion Injury', 'Rats', 'Rats, Sprague-Dawley', 'Reactive Oxygen Species'] | 28,770,953 | [['B01.050'], ['D08.811.277.087.483'], ['D12.125.068.330', 'D12.125.095.461', 'D12.125.154.424'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['C14.280.238.615', 'C14.280.647.625', 'C14.907.585.625', 'C14.907.725.600', 'C23.550.767.877.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A cohort study of antihypertensive treatments and risk of renal cell cancer. | We studied 335,682 county residents, of whom 113,298 had been prescribed antihypertensive treatment (AHT), in the period 1989-2002 in North Jutland County, Denmark to examine the relation between different AHTs and the risk of renal cell carcinoma (RCC). An internal comparison was performed among the different classes ... | ['Adult', 'Aged', 'Antihypertensive Agents', 'Carcinoma, Renal Cell', 'Cohort Studies', 'Confounding Factors, Epidemiologic', 'Denmark', 'Female', 'Humans', 'Hypertension', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Risk Factors'] | 15,812,478 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.411.162'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.240', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Tuberculosis and the acquired immunodeficiency syndrome at a New York City hospital: 1978-1985. | Recent reports have described an increase in cases of tuberculosis in several urban centers. To investigate the possible relationship between tuberculosis and the acquired immunodeficiency syndrome (AIDS), we reviewed case records at a New York City hospital between 1978 and 1985. During this period, tuberculosis occur... | ['AIDS-Related Complex', 'Acquired Immunodeficiency Syndrome', 'Adult', 'Female', 'Hospitals, Urban', 'Humans', 'Male', 'Middle Aged', 'Mycobacterium Infections', 'New York City', 'Population Surveillance', 'Substance-Related Disorders', 'Tuberculosis', 'Tuberculosis, Pulmonary'] | 3,802,929 | [['C01.221.250.875.080', 'C01.221.812.640.400.080', 'C01.778.640.400.080', 'C01.925.782.815.616.400.080', 'C01.925.813.400.080', 'C01.925.839.080', 'C20.673.480.080'], ['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Amplification of transgene expression in vitro and in vivo using a novel inhibitor of histone deacetylase. | Enhancement of transgene expression is an important issue in human gene therapy. Here we describe a novel system for enhancing transgene expression by cointroduction of plasmid DNA with FR901228, a water-soluble histone deacetylase inhibitor. When a luciferase expression vector was cointroduced into cells with FR901228... | ['Animals', 'Anti-Bacterial Agents', 'Depsipeptides', 'Enzyme Inhibitors', 'Gene Expression', 'Genes, Reporter', 'Genetic Therapy', 'Histone Deacetylase Inhibitors', 'Humans', 'Luciferases', 'Male', 'Melanoma, Experimental', 'Mice', 'Mice, Inbred C57BL', 'Peptides, Cyclic', 'Transfection', 'Tumor Cells, Cultured'] | 10,933,982 | [['B01.050'], ['D27.505.954.122.085'], ['D04.345.566.297', 'D12.644.641.297'], ['D27.505.519.389'], ['G05.297'], ['G05.360.340.024.340.435'], ['E02.095.301', 'E05.393.420.301'], ['D27.505.519.389.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.517', 'D12.776.532.510'], ['C04.557.465.625.650.510.52... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ebola virus screening during pregnancy in West Africa: unintended consequences. | OBJECTIVE: We hypothesized that predictive value of traditional Ebola virus disease (EVD) screening in West African pregnant women is low because febrile and hemorrhagic complications of pregnancy that can mimic EVD are common.METHODS: Proportions of various categories of pregnancy loss from a hypothetical cohort of We... | ['Female', 'Hemorrhagic Fever, Ebola', 'Humans', 'Incidence', 'Kaplan-Meier Estimate', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Prenatal Care', 'Sierra Leone'] | 26,098,697 | [['C01.925.782.417.415', 'C01.925.782.580.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['E05.318.370.800.650', '... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Direct-from-sputum rapid phenotypic drug susceptibility test for mycobacteria. | BACKGROUND: The spread of multi-drug resistant tuberculosis (MDR-TB) is a leading global public-health challenge. Because not all biological mechanisms of resistance are known, culture-based (phenotypic) drug-susceptibility testing (DST) provides important information that influences clinical decision-making. Current p... | ['Anti-Bacterial Agents', 'Dielectric Spectroscopy', 'Electric Impedance', 'Magnetite Nanoparticles', 'Microbial Sensitivity Tests', 'Mycobacterium', 'Proof of Concept Study', 'Sputum'] | 32,857,802 | [['D27.505.954.122.085'], ['E05.196.867.335'], ['G01.358.500.249.277.350'], ['J01.637.512.600.500.144.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.510.024.962.500', 'B03.510.460.400.410.552.552'], ['H01.770.644.578'], ['A12.200.808']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
S-Adenosyl-l-methionine activates the cardiac ryanodine receptor. | S-Adenosyl-l-methionine (SAM) is the biological methyl-group donor for the enzymatic methylation of numerous substrates including proteins. SAM has been reported to activate smooth muscle derived ryanodine receptor calcium release channels. Therefore, we examined the effects of SAM on the cardiac isoform of the ryanodi... | ['Adenosine Triphosphate', 'Animals', 'Heart', 'Methylation', 'Ryanodine', 'Ryanodine Receptor Calcium Release Channel', 'S-Adenosylmethionine'] | 18,402,770 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A07.541'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['D02.455.849.291.686', 'D03.132.740', 'D03.383.129.578.805'], ['D12.776.157.530.400.150.800', 'D12.776.210.500.800', 'D12.776.543.550.450.150.800', 'D12.776.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Uterine artery embolization in sheep: comparison of acute effects with polyvinyl alcohol particles and calibrated microspheres. | PURPOSE: To compare the effects on the myometrium of polyvinyl alcohol (PVA) particles and calibrated microspheres (MS) in embolization of the uterine arteries in sheep.MATERIALS AND METHODS: Superselective and bilateral embolization of the uterine arteries was performed with PVA particles and calibrated MS within 24 h... | ['Angiography', 'Animals', 'Arteries', 'Catheterization', 'Embolization, Therapeutic', 'Female', 'Magnetic Resonance Imaging', 'Microspheres', 'Necrosis', 'Particle Size', 'Polyvinyl Alcohol', 'Polyvinyls', 'Sheep', 'Uterus'] | 12,147,840 | [['E01.370.350.700.060', 'E01.370.370.050'], ['B01.050'], ['A07.015.114'], ['E02.148', 'E05.157'], ['E02.520.360', 'E02.926.500'], ['E01.370.350.825.500'], ['E07.565'], ['C23.550.717'], ['G02.712'], ['D02.033.750', 'D02.455.326.271.884.533.532', 'D05.750.716.721.616', 'D25.720.716.721.616', 'J01.637.051.720.716.721.616... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Electric stimulation regulates the level of Ca-channels in chick muscle culture. | To examine the role of muscle activity in the expression of 1,4-dihydropyridine (DHP)-sensitive Ca-channels, we electrically stimulated chick skeletal muscle cells growing in culture. The number of Ca-channels was determined by a radioligand binding technique using [3H]PN200-110. The function of these channels was meas... | ['Acetylcholinesterase', 'Animals', 'Calcium Channels', 'Chick Embryo', 'Culture Techniques', 'Electric Stimulation', 'Isradipine', 'Muscles', 'Potassium'] | 8,385,756 | [['D08.811.277.352.100.170.176'], ['B01.050'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['A13.350.150', 'A16.331.200'], ['E05.481.500'], ['E05.723.402'], ['D03.383.725.203.310'], ['A02.633', 'A10.690'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Can Renal Resistive Index Predict Acute Kidney Injury After Acute Type A Aortic Dissection Repair? | BACKGROUND: This study sought to determine whether assessment of the renal resistive index (RRI) can predict the short-term reversibility of acute kidney injury (AKI) after repair of acute type A aortic dissection (TAAD).METHODS: This prospective study included 62 patients undergoing repair of acute TAAD. Doppler-based... | ['Acute Kidney Injury', 'Aged', 'Aneurysm, Dissecting', 'Aortic Aneurysm, Thoracic', 'Cohort Studies', 'Computed Tomography Angiography', 'Confidence Intervals', 'Creatinine', 'Female', 'Humans', 'Kidney Function Tests', 'Linear Models', 'Male', 'Middle Aged', 'Postoperative Care', 'Predictive Value of Tests', 'Prospec... | 28,619,541 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116.100'], ['C14.907.055.050'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of Clostridium botulinum 52A toxicity and protease activity by sodium acid pyrophosphate in media systems. | The effects of two pH levels (5.55 or 5.85) in combination with 0.4% sodium acid pyrophosphate (SAPP), NaH2PO4 X H2O, Na2HPO4 X 7H2O, or NaCl on the growth and toxicity of Clostridium botulinum 52A were studied. Absorbancy measurements at 630 nm, microscopic observations, and the mouse bioassay procedure were used to o... | ['Botulinum Toxins', 'Clostridium botulinum', 'Diphosphates', 'Hydrogen-Ion Concentration', 'Microscopy, Phase-Contrast', 'Phosphates', 'Protease Inhibitors', 'Sodium Chloride', 'Trypsin'] | 2,992,374 | [['D08.811.277.656.300.480.153', 'D08.811.277.656.675.374.153', 'D12.776.097.156', 'D23.946.123.179'], ['B03.300.390.400.200.160', 'B03.353.625.375.500.160', 'B03.510.415.400.200.160'], ['D01.029.260.700.675.374.775.150', 'D01.248.497.158.730.650.200', 'D01.695.625.675.650.775.150'], ['G02.300'], ['E01.370.350.515.513.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antenatal diagnosis of glutaric acidemia. | Two pregnancies at risk for glutaric acidemia were monitored. In one, in which the fetus was not affected, glutaric acid was not detected in the amniotic fluid at amniocentesis (15 weeks) and the glutaryl-CoA dehydrogenase activity of cultured amniotic cells was normal. In the other, a marked elevation of glutaric acid... | ['Acyl Coenzyme A', 'Amino Acid Metabolism, Inborn Errors', 'Amniocentesis', 'Amniotic Fluid', 'Cells, Cultured', 'Female', 'Glutarates', 'Glutaryl-CoA Dehydrogenase', 'Humans', 'Infant, Newborn', 'Male', 'Oxidoreductases', 'Oxidoreductases Acting on CH-CH Group Donors', 'Pregnancy', 'Prenatal Diagnosis'] | 6,893,520 | [['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['C16.320.565.100', 'C18.452.648.100'], ['E01.370.225.500.384.050', 'E01.370.225.998.329.309', 'E01.370.378.630.050', 'E04.665.600.309', 'E05.200.500.384.050', 'E05.200.998.329.309', 'E05.242.384.050'], ['A12.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. | ABCG5 (G5) and ABCG8 (G8) are ATP-binding cassette (ABC) transporters that limit intestinal absorption and promote biliary excretion of neutral sterols. Mutations in either ABCG5 or ABCG8 result in an identical clinical phenotype, suggesting that these two half-transporters function as heterodimers. Expression of both ... | ['ATP Binding Cassette Transporter, Subfamily G, Member 5', 'ATP Binding Cassette Transporter, Subfamily G, Member 8', 'ATP-Binding Cassette Transporters', 'Adenosine Triphosphate', 'Adenoviridae', 'Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Bile Ducts', 'Biological Transport', 'CHO Cells', 'Cell Membr... | 14,504,269 | [['D10.532.137', 'D12.776.157.530.100.228.750', 'D12.776.395.550.020.457.750', 'D12.776.521.181', 'D12.776.543.550.192.457.750', 'D12.776.543.585.100.228.750'], ['D10.532.160', 'D12.776.157.530.100.228.875', 'D12.776.395.550.020.457.875', 'D12.776.521.212', 'D12.776.543.550.192.457.875', 'D12.776.543.585.100.228.875'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Gallbladder tuberculosis (case report and review of the literature). | The incidence of abdominal tuberculosis is increasing and the familiarity with its clinical presentation shortens its diagnostic time and improves its management. Gallbladder tuberculosis has unique considerations regarding its pathology, diagnosis and surgical management. The authors report a case of gallbladder tuber... | ['Antitubercular Agents', 'Cholecystectomy', 'Cholecystitis', 'Cholelithiasis', 'Diagnosis, Differential', 'Drug Therapy, Combination', 'Female', 'Gallbladder', 'Gallbladder Diseases', 'Humans', 'Lymph Nodes', 'Middle Aged', 'Tuberculosis', 'Ultrasonography'] | 10,576,349 | [['D27.505.954.122.085.255'], ['E04.210.120.172'], ['C06.130.564.263'], ['C06.130.409'], ['E01.171'], ['E02.319.310'], ['A03.159.439'], ['C06.130.564'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.549.400', 'A15.382.520.604.412'], ['M01.060.116.630'], ['C01.150.252.410.040.552.846'], ['E01.370.350.850']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Lack of association between preference for and dependence on ethanol. | Tests were performed on 60 HS mice to determine preference for ethanol before and after a period of forced ethanol ingestion via a liquid diet treatment. Seizure scores measured 4, 5 and 6 h after the end of the liquid diet treatment showed that moderate degrees of physical dependence had developed. Statistical analyse... | ['Alcoholism', 'Animals', 'Behavior, Animal', 'Choice Behavior', 'Ethanol', 'Female', 'Humans', 'Male', 'Mice', 'Seizures', 'Substance Withdrawal Syndrome'] | 7,201,379 | [['C25.775.100.250', 'F03.900.100.350'], ['B01.050'], ['F01.145.113'], ['F02.463.785.373.346'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['C10.597.742', 'C23.888.592.742'], ['C25.775.835', 'F03.900.825']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Topical effect of a medically prescribed pediatric antibiotic on dental biofilm: a cross-over, in situ study. | OBJECTIVE: This study aimed to investigate the possible topical effect of a broad-spectrum antibiotic on dental biofilm formed in situ in the absence or presence of sucrose.METHODS: A crossover study was conducted in three phases of 14 days each, during which 11 volunteers wore palatal devices containing 6 enamel block... | ['Administration, Topical', 'Adult', 'Anti-Bacterial Agents', 'Biofilms', 'Colony Count, Microbial', 'Cross-Over Studies', 'Dental Plaque', 'Female', 'Humans', 'Male', 'Metagenome', 'RNA, Ribosomal, 16S', 'Sucrose', 'Young Adult'] | 23,383,224 | [['E02.319.267.120'], ['M01.060.116'], ['D27.505.954.122.085'], ['A20.593', 'G06.120'], ['E01.370.225.875.220', 'E05.200.875.220'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C07.793.208.377'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.550'], ['D13.444.735.686.670'], ['D09... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Does Cardiorespiratory Fitness Attenuate the Adverse Effects of Severe/Morbid Obesity on Cardiometabolic Risk and Insulin Resistance in Children? A Pooled Analysis. | OBJECTIVE: To investigate 1) differences in cardiometabolic risk and HOMA of insulin resistance (HOMA-IR) across BMI categories (underweight to morbid obesity), 2) whether fit children have lower cardiometabolic risk/HOMA-IR than unfit children in each BMI category, and 3) differences in cardiometabolic risk/HOMA-IR in... | ['Blood Glucose', 'Blood Pressure', 'Body Mass Index', 'Cardiorespiratory Fitness', 'Child', 'Child, Preschool', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Cross-Sectional Studies', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Insulin', 'Insulin Resistance', 'Male', 'Obesity, Morbid', 'Risk Factors', 'Triglycerides'] | 28,939,688 | [['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.685.500', 'I03.450.642.845.054.300', 'I03.450.642.845.054.800.500', 'N01.400.150', 'N01.400.545.500'], ['M01.060.406'], ['M01.060.406.448'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Decision making around dialysis options. | INTRODUCTION: We have previously shown that information given to patients approaching end stage renal failure to make an informed decision about dialysis modality is frequently incomplete and difficult to comprehend [1]. We have now studied whether there are differences in decisions made about dialysis modality accordi... | ['Decision Making', 'Female', 'Health Surveys', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Patient Education as Topic', 'Peritoneal Dialysis', 'Renal Dialysis'] | 19,494,622 | [['F02.463.785.373'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['I02.233.332.500', 'N02.421.726.407.680'], ['E02.870.300.650', 'E02.912.800.650'], ['E02.870.300', 'E02.912.8... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Generation of synthetic data and experimental designs in evaluating interactions for association studies. | Complex diseases, by definition, involve multiple factors, including gene-gene interactions and gene-environment interactions. Researchers commonly rely on simulated data to evaluate their approaches for detecting high-order interactions in disease gene mapping. A publicly available simulation program to generate sampl... | ['Algorithms', 'Databases, Factual', 'Gene-Environment Interaction', 'Genotype', 'Research Design', 'Software'] | 22,809,306 | [['G17.035', 'L01.224.050'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['G05.695.337'], ['G05.380'], ['E05.581.500', 'H01.770.644.728'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
NLR Family Pyrin Domain-Containing 3 Inflammasome Activation in Hepatic Stellate Cells Induces Liver Fibrosis in Mice. | The NLR family pyrin domain-containing 3 (NLRP3) inflammasome plays an important role in liver fibrosis (LF) development. However, the mechanisms involved in NLRP3-induced fibrosis are unclear. Our aim was to test the hypothesis that the NLRP3 inflammasome in hepatic stellate cells (HSCs) can directly regulate their ac... | ['Animals', 'Biomarkers', 'Female', 'Hepatic Stellate Cells', 'Inflammasomes', 'Lipopolysaccharides', 'Liver', 'Liver Cirrhosis', 'Male', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Myofibroblasts', 'NLR Family, Pyrin Domain-Containing 3 Protein'] | 30,180,270 | [['B01.050'], ['D23.101'], ['A11.561'], ['D05.500.224'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A03.620'], ['C06.552.630', 'C23.550.355.412'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500', 'B01.050.150.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attitudes of some young female bank employees to dentistry. | Structured interviews were undertaken with one hundred 18-30-year-old females, seeking their views on dental care. Almost all regarded their own past experience as affecting their general level of dental anxiety. Over half were anxious about visiting the dentist and almost all of these were anxious before entering the ... | ['Adolescent', 'Adult', 'Anxiety', 'Attitude to Health', 'Dental Care', 'Female', 'Humans', 'Wales'] | 2,732,366 | [['M01.060.057'], ['M01.060.116'], ['F01.470.132'], ['F01.100.150', 'N05.300.150'], ['E06.170', 'N02.421.240.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.363.914']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A study of the energy absorption and exposure buildup factors of some anti-inflammatory drugs. | Human radiation exposure is increasing due to radiation development in science and technology. The development of radioprotective agents is important for protecting patients from the side effects of radiotherapy and for protecting the public from unwanted irradiation. Radioprotective agents are used to reduce the damag... | ['Absorption, Radiation', 'Anti-Inflammatory Agents', 'Computer Simulation', 'Materials Testing', 'Models, Chemical', 'Photons', 'Radiation-Protective Agents'] | 24,859,334 | [['G01.015.249.500', 'G01.750.124', 'G02.010.500.500'], ['D27.505.954.158'], ['L01.224.160'], ['E05.570'], ['E05.599.495'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['D27.505.696.706.776', 'D27.720.799.763']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Blackberries as raw--material for manufacturing prophylactic foods]. | A possibility of using wild blackberries as raw for manufacturing prophylactic foods was scrutinized. | ['Diet Therapy', 'Food Additives', 'Food Analysis', 'Fruit'] | 18,669,338 | [['E02.642.249'], ['D27.720.372.300', 'G07.203.300.514.500', 'J02.500.514.500'], ['E05.362', 'J01.576.423.850.100'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Interlaboratory comparison and accreditation in quality control testing of diagnostic X-ray equipment. | The University of Tartu provides a quality control service to the majority of diagnostic X-ray departments in Estonia. Its methodology has been adopted from the IEC and other relevant standards. Recently the Testing Centre of the University of Tartu was accredited on this methodology by ISO/IEC 17025. Besides the imple... | ['Accreditation', 'Humans', 'Laboratories, Hospital', 'Models, Statistical', 'Quality Control', 'Radiation Dosage', 'Radiation Monitoring', 'Radiometry', 'Research Design', 'Technology, Radiologic', 'X-Rays'] | 15,933,108 | [['N03.706.110.070', 'N05.700.200.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.420', 'N02.278.487.410', 'N04.452.442.452.422.420'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['J01.897.608'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E05... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
A mixed-method evaluation of nurse-led community-based supportive cancer care. | GOALS OF WORK: The study purpose was to evaluate a nurse-led supportive care clinical case management program in the community using multi-methods to delineate care processes prior to outcome evaluation.MATERIALS AND METHODS: Multiple data sources including program service records, chart reviews and interviews with nur... | ['Adult', 'Aged', 'Aged, 80 and over', 'Case Management', 'Community Health Services', 'Continuity of Patient Care', 'Female', 'Home Care Services', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Nurse Clinicians', 'Patient Care Planning', 'Social Support', 'Young Adult'] | 18,335,260 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N04.590.233.624.250'], ['N02.421.143'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ['M01.526.485.650.648.525', 'N02.360... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Desulfotomaculum peckii sp. nov., a moderately thermophilic member of the genus Desulfotomaculum, isolated from an upflow anaerobic filter treating abattoir wastewaters. | A novel anaerobic thermophilic sulfate-reducing bacterium designated strain LINDBHT1(T) was isolated from an anaerobic digester treating abattoir wastewaters in Tunisia. Strain LINDBHT1(T) grew at temperatures between 50 and 65 °C (optimum 55-60 °C), and at pH between 5.9 and 9.2 (optimum pH 6.0-6.8). Strain LINDBHT1(T... | ['Abattoirs', 'Bacterial Typing Techniques', 'Base Composition', 'DNA, Bacterial', 'Desulfotomaculum', 'Fatty Acids', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Sulfates', 'Sulfites', 'Tunisia', 'Waste Water'] | 23,064,354 | [['J01.576.423.200.700.100', 'J03.540.020'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['D13.444.308.212'], ['B03.353.625.782.297', 'B03.510.415.400.230', 'B03.900.300'], ['D10.251'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['E05.393.760.700'],... | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Eigenspine: computing the correlation between measures describing vertebral pose for patients with adolescent idiopathic scoliosis. | This paper describes the concept of eigenspine, a concept applicable for determining the correlation between pair-wise combinations of measures useful for describing the three-dimensional spinal deformities associated with adolescent idiopathic scoliosis. The proposed data analysis scheme is based upon the use of princ... | ['Adolescent', 'Algorithms', 'Data Interpretation, Statistical', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Lumbar Vertebrae', 'Male', 'Numerical Analysis, Computer-Assisted', 'Patient Positioning', 'Pattern Recognition, Automated', 'Principal Component Analysis', 'Radiographic Image Enhancement', 'Radiographic... | 25,066,008 | [['M01.060.057'], ['G17.035', 'L01.224.050'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['A02.835.232.834.519'], ['L01.224.680.700'], ['E02.760.670', 'N02.421.585.7... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
MRI of lymphomas of the orbits and the paranasal sinuses. | PURPOSE: The purpose of this study was to point out MR characteristics of non-Hodgkin lymphomas of the orbits and the paranasal sinuses and the benefit of fat-suppressed contrast-enhanced sequences.METHOD: The MR images of 16 patients with lymphoma of the orbits and the paranasal sinuses were retrospectively analyzed f... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Contrast Media', 'Female', 'Gadolinium DTPA', 'Humans', 'Lymphoma, Non-Hodgkin', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Orbital Neoplasms', 'Paranasal Sinus Neoplasms', 'Retrospective Studies'] | 9,386,277 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.259.500', 'D27.720.259'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['E01.370.350.825.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of necrotic lesion size and orientation of the femoral component on stress alterations in the proximal femur in hip resurfacing - a finite element simulation. | BACKGROUND: Due to the advantages of its bone-conserving nature, hip resurface arthroplasty (HRA) has recently gained the interest of orthopedic surgeons for the treatment of young and active patients who have osteonerosis of the femoral head. However, in long-term follow-up studies after HRA, narrowing of the femoral ... | ['Arthroplasty, Replacement, Hip', 'Biomechanical Phenomena', 'Computer Simulation', 'Femur Head Necrosis', 'Finite Element Analysis', 'Hip Prosthesis', 'Humans', 'Models, Anatomic', 'Prosthesis Design', 'Prosthesis Failure', 'Stress, Mechanical', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 25,095,740 | [['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['G01.154.090', 'G01.374.089'], ['L01.224.160'], ['C05.116.852.175', 'C23.550.717.732.368'], ['E05.355'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['E05.320.550', 'E07... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Prevalence of hepatitis B markers among hospital workers in Senegal. | A total of 775 serum samples from men and women working in hospitals in Dakar, Senegal, were tested for serological markers of hepatitis B virus (HBV). HBsAg was detected in 17.8% of the subjects, and 79.2% of the subjects were anti-HBc positive. Among HBsAg carriers 0.04% (5) subjects were HBeAg positive, 0.03% (4) we... | ['Adult', 'Biomarkers', 'Cross-Sectional Studies', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Hepatitis B Antibodies', 'Hepatitis B Antigens', 'Hepatitis B virus', 'Hepatitis Delta Virus', 'Humans', 'Immunoblotting', 'Male', 'Occupational Diseases', 'Personnel, Hospital', 'Risk Factors', 'Senegal'] | 2,786,051 | [['M01.060.116'], ['D23.101'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.790.651.114.254.450.504', 'D12.776.377.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comparison of isoflurane and halothane safety margins in rats. | In rat experiments, the dose-effect curves for three different end points of anesthesia [loss of righting reflex (RR), prevention of movement (PM), and heart rate response (HR) to noxious stimuli] and for the lethal effect (LE) due to cardiovascular depression were determined with isoflurane and halothane. The obtained... | ['Anesthesia, Inhalation', 'Animals', 'Brain', 'Dose-Response Relationship, Drug', 'Halothane', 'Heart Rate', 'Isoflurane', 'Lethal Dose 50', 'Methyl Ethers', 'Movement', 'Postural Balance', 'Rats', 'Rats, Inbred Strains'] | 6,859,586 | [['E03.155.197.197'], ['B01.050'], ['A08.186.211'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.455.526.340'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D02.355.601.570'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['D02.355.601'], ['G07.568', 'G11.427.410'], ['F02.830.816.541.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physical clustering of FLC alleles during Polycomb-mediated epigenetic silencing in vernalization. | Vernalization, the promotion of flowering by cold, involves Polycomb-mediated epigenetic silencing of FLOWERING LOCUS C (FLC). Cold progressively promotes cell-autonomous switching to a silenced state. Here, we used live-cell imaging of FLC-lacO to monitor changes in nuclear organization during vernalization. FLC-lacO ... | ['Alleles', 'Arabidopsis', 'Arabidopsis Proteins', 'Carrier Proteins', 'Chromosomal Proteins, Non-Histone', 'Cold Temperature', 'DNA-Binding Proteins', 'Epigenesis, Genetic', 'Gene Expression Regulation, Plant', 'Gene Silencing', 'MADS Domain Proteins', 'Multigene Family', 'Nuclear Proteins', 'Plant Roots', 'Polycomb-G... | 24,013,499 | [['G05.360.340.024.340.030'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D12.776.157'], ['D12.776.660.235', 'D12.776.664.235'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D12.776.260'], ['G05.308.203'], ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prevalence of Sarcopenia and Associated Factors in Chinese Community-Dwelling Elderly: Comparison Between Rural and Urban Areas. | OBJECTIVES: To compare the prevalence of sarcopenia in urban and rural Chinese elderly adults and to identify the risk factors related to sarcopenia.DESIGN: A cross-sectional study.SETTING: Urban and rural communities in western China.PARTICIPANTS: A total of 887 community-dwelling elderly adults aged 60 years or older... | ['Aged', 'Aged, 80 and over', 'China', 'Comorbidity', 'Cross-Sectional Studies', 'Female', 'Geriatric Assessment', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Rural Population', 'Sarcopenia', 'Urban Population'] | 26,385,304 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.252.474.164'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], [... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Monoclonal antibodies recognizing mucus immunoglobulin and surface immunoglobulin-positive cells of flounder (Paralichthys olivaceus). | Mucus immunoglobulin (Ig) of flounder (Paralichthys olivaceus) was purified by the combination of salting-out, Sephacryl S-300 gel filtration chromatography and DEAE Sepharose chromatography. According to the SDS-PAGE and native-PAGE, the purified mucus Ig showed apparent molecular weights of 72 kDa (heavy chain) and 2... | ['Animals', 'Antibodies, Monoclonal', 'Blotting, Western', 'Chromatography, Gel', 'Enzyme-Linked Immunosorbent Assay', 'Flounder', 'Immunoglobulin Heavy Chains', 'Immunoglobulins', 'Lymphocytes', 'Mice', 'Mice, Inbred BALB C', 'Molecular Weight', 'Mucus', 'Receptors, Antigen, B-Cell'] | 22,209,367 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.181.400.250'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.35... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spreading behaviour of cultured fibroblasts from carriers of Duchenne muscular dystrophy. | Cultured skin fibroblasts from patients with Duchenne muscular dystrophy (DMD) are more sensitive than normal cells to prolonged exposure to the ionophore monensin. In a cell spreading assay in which cells were preincubated with monensin and subsequently allowed to adhere to and spread on a glass substratum in serum-fr... | ['Cell Adhesion', 'Cells, Cultured', 'Fibroblasts', 'Heterozygote', 'Humans', 'Monensin', 'Muscular Dystrophies', 'Skin'] | 3,667,711 | [['G04.022'], ['A11.251'], ['A11.329.228'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.312.600'], ['C05.651.534.500', 'C10.668.491.175.500', 'C16.320.577'], ['A17.815']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. | The c-Jun NH(2)-terminal kinase (JNK) is activated when cells are exposed to environmental stress, including UV radiation. Gene disruption studies demonstrate that JNK is essential for UV-stimulated apoptosis mediated by the mitochondrial pathway by a Bax/Bak-dependent mechanism. Here, we demonstrate that JNK phosphory... | ['Adaptor Proteins, Signal Transducing', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Bcl-2-Like Protein 11', 'Carrier Proteins', 'Cell Line', 'DNA Mutational Analysis', 'DNA, Complementary', 'Fibroblasts', 'Humans', 'Membrane Proteins', 'Mitochondria', 'Models, Biological', 'Neurons', 'Phosphorylation', 'Plasmids', ... | 12,591,950 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['D12.644.360.075.323', 'D12.776.476.075.323', 'D12.776.543.116', 'D12.776.624.664.700.025'], ['D12.776.157'], ['A11.251.210'], ['E05.393.760.700.300'], ['D13.444.308.497.220', 'D13.444.600.223.500',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The influence of the H5?OC4 intramolecular hydrogen-bond (IHB) on the antioxidative activity of flavonoid. | Flavonoids widely found in natural foods are characterized by acting as antioxidants compounds. There are close relationship between the antiradical activities and structural properties of flavonoids. In this work, density functional theory (DFT) methods were applied to investigate the influence of the H5?OC4 intramole... | ['Antioxidants', 'Electron Transport', 'Flavonoids', 'Free Radicals', 'Hydrogen Bonding', 'Structure-Activity Relationship', 'Thermodynamics'] | 30,669,059 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D01.339', 'D02.389'], ['G02.282'], ['G02.111.830', 'G07.690.773.997'], ['G01.906']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Who Really Wins? Efficacy of a Croatian Youth Gambling Prevention Program. | This paper reports on the development and pilot evaluation of a Croatian school-based youth gambling prevention program "Who really wins?". The program is aimed at minimizing risk and enhancing protective factors related to youth gambling. A short-term evaluation of the program was conducted with a sample of 190 first ... | ['Adolescent', 'Adolescent Behavior', 'Cognitive Behavioral Therapy', 'Croatia', 'Female', 'Gambling', 'Humans', 'Male', 'Program Evaluation', 'School Health Services', 'Schools', 'Self Efficacy', 'Students'] | 28,108,811 | [['M01.060.057'], ['F01.145.022'], ['F04.754.137.350'], ['Z01.542.248.295'], ['F01.145.722.408', 'F03.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['N02.421.726.809'], ['I02.783', 'J03.832'], ['F01.752.747.792.700'], ['M01.848']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Intracellular Fate of Nanoparticles with Polydopamine Surface Engineering and a Novel Strategy for Exocytosis-Inhibiting, Lysosome Impairment-Based Cancer Therapy. | Polydopamine (PDA) coating as a bioinspired strategy for nanoparticles (NPs) has been extensively applied in cancer theranostics. However, a cellular-level understanding of nano-biointeraction of these PDA-coated NPs (PDNPs), which drives the fate of them and acts as a critical step to determine their efficacy, still r... | ['Animals', 'Antineoplastic Agents', 'Drug Carriers', 'Endocytosis', 'Exocytosis', 'HeLa Cells', 'Humans', 'Indoles', 'Lysosomes', 'Mice', 'Nanoparticles', 'Neoplasms', 'Pinocytosis', 'Polymers', 'Silicon Dioxide'] | 29,058,908 | [['B01.050'], ['D27.505.954.248'], ['D26.255.260', 'E02.319.300.380'], ['G04.417'], ['G04.468'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473'], ['A11.284.430.214.190.875.190.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['J01.63... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Modification of the saccharide structures of orosomucoid in rats stimulated by treatment with phenobarbital]. | The administration of phenobarbital (80 mg/kg body weight for 3 days) increased the plasma orosomucoid level with dramatic alterations in the relative proportions of heteroglycans. A crossed immunoaffinoelectrophoresis with Con A revealed an increase of strongly reactive fractions with a concomitant decrease of non and... | ['Animals', 'Concanavalin A', 'Immunoelectrophoresis, Two-Dimensional', 'Male', 'Oligosaccharides', 'Orosomucoid', 'Phenobarbital', 'Rats', 'Rats, Inbred Strains'] | 3,933,771 | [['B01.050'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['E01.370.225.812.735.645.350.350.350', 'E05.196.401.568.520', 'E05.200.812.735.645.350.350.350', 'E05.301.300.568.520', 'E05.478.594.760.645.350.350.350', 'E05.478.605.492.350.350.350'], ['D09.698.629'], ['D12.776.124.050.600', 'D12.776.124.790.106.640', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The aberrancy of immunophenotype and immunoglobulin status as indicators of prognosis in B cell diffuse large cell lymphoma. | To assess the prognostic significance of the immunophenotype in diffuse large cell lymphoma (DLCL), 105 DLCL patients were studied between 1978 and 1987 using a panel of 40 monoclonal antibodies applied to frozen tissue. Eighty-three patients were found to have B cell phenotypes, and 20 patients had T cell phenotypes. ... | ['Antigens, Surface', 'B-Lymphocytes', 'Female', 'HLA-DR Antigens', 'Humans', 'Immunoenzyme Techniques', 'Immunoglobulin Light Chains', 'Immunoglobulin kappa-Chains', 'Lymphoma', 'Male', 'Neoplasm Staging', 'Phenotype', 'Prognosis', 'Statistics as Topic', 'T-Lymphocytes'] | 3,140,668 | [['D23.050.301'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.395.550.509.400.440', 'D12.776.543.550.440.400.440', 'D23.050.301.500.400.400.440', 'D23.050.301.500.450.400.440', 'D23.050.705.552.410.400.440', 'D23.050.705.552.450.400.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Which landmark results in a more consistent diagnosis of Barrett's esophagus, the gastric folds or the palisade vessels? | BACKGROUND: The endoscopic landmark used to diagnose Barrett's esophagus differs between Japanese and Western endoscopists.OBJECTIVE: To compare the degree of diagnostic variation in results achieved by Japanese endoscopists when using the palisade vessels as a landmark of the distal esophagus and when using the gastri... | ['Barrett Esophagus', 'Clinical Competence', 'Endoscopy, Digestive System', 'Esophagogastric Junction', 'Humans', 'Sensitivity and Specificity'] | 16,860,070 | [['C04.834.154', 'C06.405.117.102'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E01.370.372.250', 'E01.370.388.250.250', 'E04.210.240', 'E04.502.250.250'], ['A03.556.875.500.414', 'A03.556.875.875.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.71... | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Fatal systemic morbillivirus infection in bottlenose dolphin, canary islands, Spain. | A systemic morbillivirus infection was diagnosed postmortem in a juvenile bottlenose dolphin stranded in the eastern North Atlantic Ocean in 2005. Sequence analysis of a conserved fragment of the morbillivirus phosphoprotein gene indicated that the virus is closely related to dolphin morbillivirus recently reported in ... | ['Animals', 'Bottle-Nosed Dolphin', 'Female', 'Morbillivirus', 'Morbillivirus Infections', 'Phylogeny', 'Spain', 'Viral Proteins'] | 24,447,792 | [['B01.050'], ['B01.050.150.900.649.313.875.267.100'], ['B04.820.480.937.600.650.500'], ['C01.925.782.580.600.500'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['Z01.542.846'], ['D12.776.964']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Chlordiazepoxide concentrations in saliva and plasma measured by radioimmunoassay. | A new, sensitive and specific radioimmunoassay (RIA) for chlordiazepoxide was used to determine concentrations of the drug in microsamples of saliva and plasma obtained from subjects following intravenous and oral administration of the drug. Saliva and plasma concentrations of the drug were highly correlated (r = 0.95)... | ['Chlordiazepoxide', 'Half-Life', 'Humans', 'Radioimmunoassay', 'Saliva', 'Time Factors'] | 7,367,755 | [['D03.633.100.079.080.150'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['A12.200.666'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of a novel polyomavirus isolated from a fibroma on the trunk of an African elephant (Loxodonta africana). | Viruses of the family Polyomaviridae infect a wide variety of avian and mammalian hosts with a broad spectrum of outcomes including asymptomatic infection, acute systemic disease, and tumor induction. In this study a novel polyomavirus, the African elephant polyomavirus 1 (AelPyV-1) found in a protruding hyperplastic f... | ['Animals', 'Antigens, Viral, Tumor', 'Capsid Proteins', 'DNA, Viral', 'Elephants', 'Fibroma', 'Genome, Viral', 'High-Throughput Nucleotide Sequencing', 'Phylogeny', 'Polyomavirus', 'Polyomavirus Infections', 'Tumor Virus Infections'] | 24,205,012 | [['B01.050'], ['D23.050.285.062', 'D23.050.327.062'], ['D12.776.964.970.600.550'], ['D13.444.308.568'], ['B01.050.150.900.649.833.249'], ['C04.557.450.565.590.340'], ['G05.360.340.358.840'], ['E05.393.760.319'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B04.280.210.700.615', 'B04.613.204.670.615'], ['C01.925.256.721... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Intake of total cruciferous vegetable and its contents of glucosinolates and isothiocyanates, glutathione S | Cruciferous vegetables contain high levels of glucosinolates (GSL) and isothiocyanates (ITC). ITC are known to induce glutathione S-transferases (GST) and thus exert their anticarcinogenic effects. This study explored the combined effects of cruciferous vegetable, GSL and ITC intake and GST polymorphisms on breast canc... | ['Adult', 'Aged', 'Breast Neoplasms', 'Case-Control Studies', 'China', 'Diet', 'Female', 'Genetic Predisposition to Disease', 'Glucosinolates', 'Glutathione Transferase', 'Humans', 'Isothiocyanates', 'Middle Aged', 'Polymorphism, Genetic', 'Risk Factors', 'Vegetables'] | 32,308,174 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['Z01.252.474.164'], ['G07.203.650.240'], ['C23.550.291.687.500', 'G05.380.355'], ['D02.886.740.703.350', 'D09.408.348.820.350', 'D09.408.903.703.350'], ['D08.811.913... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Transplacental transport of paracetamol and its phase II metabolites using the ex vivo placenta perfusion model. | In Europe, 50-60% of pregnant women uses paracetamol (PCM), also known as acetaminophen. While it was considered to be safe, recent studies have shown an association between prenatal exposure to PCM and increased incidences of autism, cryptorchidism, asthma and ADHD. In this study the transplacental transfer of PCM and... | ['Acetaminophen', 'Adult', 'Female', 'Fetus', 'Gestational Age', 'Humans', 'In Vitro Techniques', 'Maternal-Fetal Exchange', 'Perfusion', 'Placenta', 'Pregnancy'] | 30,849,458 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['M01.060.116'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G08.686.784.769.455'], ['E05.680'], ['A16.710'], ['G08.686.784.769']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
B and T Cell Epitope-Based Peptides Predicted from Evolutionarily Conserved and Whole Protein Sequences of Ebola Virus as Vaccine Targets. | Ebola virus (EBV) has become a serious threat to public health. Different approaches were applied to predict continuous and discontinuous B cell epitopes as well as T cell epitopes from the sequence-based and available three-dimensional structural analyses of each protein of EBV. Peptides '(79) VPSATKRWGFRSGVPP(94) ' f... | ['Africa', 'Asia', 'Computational Biology', 'Computer Simulation', 'Conserved Sequence', 'Ebola Vaccines', 'Ebolavirus', 'Epitope Mapping', 'Epitopes, B-Lymphocyte', 'Epitopes, T-Lymphocyte', 'Evolution, Molecular', 'Gene Frequency', 'HLA Antigens', 'HLA-DRB1 Chains', 'Hemorrhagic Fever, Ebola', 'Humans', 'Protein Bind... | 26,939,891 | [['Z01.058'], ['Z01.252'], ['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['G02.111.570.580'], ['D20.215.894.899.205'], ['B04.820.480.937.300.200'], ['E05.478.274', 'E05.601.690.300'], ['D23.050.550.395'], ['D23.050.550.402'], ['G05.045.250', 'G16.075.250'], ['G05.330'], ['D23.050.301.500.450', 'D23.050.705.552.4... | ['Geographicals [Z]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 |
Optimal Settings for the Noncontact Holmium:YAG Stone Fragmentation Popcorn Technique. | PURPOSE: The purpose of this study was to evaluate the popcorn technique using a wide range of holmium laser settings and fiber sizes in a systematic in vitro assessment.MATERIALS AND METHODS: Evaluations were done with 4 artificial stones in a collection tube. A fixed ureteroscope was inserted through a ureteral acces... | ['Humans', 'In Vitro Techniques', 'Kidney Calculi', 'Lasers, Solid-State', 'Lithotripsy, Laser', 'Models, Biological'] | 28,442,384 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.968.967.500.503', 'C23.300.175.850.550'], ['E07.632.490.490', 'E07.710.520.490'], ['E02.594.550', 'E02.600.500', 'E04.014.52... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The future of the orthopaedic clinician-scientist. Part I: The potential role of MD-PhD students considering orthopaedic surgery. | BACKGROUND: There is currently a severe shortage of clinician-scientists, who fill a vital role in musculoskeletal care. One way to address this shortage is to recruit more MD-PhD students into orthopaedics. We analyzed data from a national survey of MD-PhD students to assess this potential.METHODS: A total of 868 stud... | ['Adult', 'Attitude of Health Personnel', 'Biomedical Research', 'Career Choice', 'Education, Graduate', 'Education, Medical', 'Female', 'Goals', 'Humans', 'Male', 'Orthopedics', 'Statistics, Nonparametric', 'Students, Medical', 'Surveys and Questionnaires', 'United States', 'Workforce'] | 18,676,927 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['H01.770.644.145'], ['F02.463.785.373.346.400'], ['I02.358.337'], ['I02.358.399'], ['F01.658.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.494'], ['E05.318.740.995', 'N05.715.360.750.760', 'N06.850.520.830.995'], ['M01.848.769.602'], ['E05.318.3... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
FMOxFMO: Elucidating Excitonic Interactions in the Fenna-Matthews-Olson Complex with the Fragment Molecular Orbital Method. | In order to study F?rster resonance energy transfer (FRET), the fragment molecular orbital (FMO) method is extended to compute electronic couplings between local excitations via the excited state transition density model, enabling efficient calculations of nonlocal excitations in a large molecular system and overcoming... | ['Bacterial Proteins', 'Bacteriochlorophyll A', 'Chlorobi', 'Fluorescence Resonance Energy Transfer', 'Light-Harvesting Protein Complexes', 'Models, Molecular', 'Quantum Theory'] | 31,841,349 | [['D12.776.097'], ['D12.776.752.249.500'], ['B03.250'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['D05.500.562.488.490', 'D08.811.600.710.490', 'D12.776.543.930.500.490', 'D12.776.765.199.750.750.490'], ['E05.599.595'], ['H01.671.579.800']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Simple methods for demonstration of epoxy resins of bisphenol A type. | Low molecular weight oligomers of epoxy resins of bisphenol A type are common sensitizers. For demonstrating the presence of sensitizing oligomers of these resins, two simple methods are described. The first one, a colour reaction, demonstrates the presence of the bisphenol A skeleton. If this test is positive, thin-la... | ['Chromatography, Thin Layer', 'Dermatitis, Contact', 'Epoxy Resins', 'Filtration', 'Humans', 'Phenols'] | 668,339 | [['E05.196.181.400.537'], ['C17.800.174.255', 'C17.800.815.255'], ['D05.750.716.822.461', 'D25.720.716.822.461', 'J01.637.051.720.716.822.461'], ['E05.196.454', 'G01.280', 'G02.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.657']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Oxidized LDL attenuates apoptosis in monocytic cells by activating ERK signaling. | Low concentrations of oxidized low density lipoprotein (OxLDL) are cytoprotective for phagocytes, although the underlying mechanisms remain unclear. We investigated signaling pathways used by OxLDL to attenuate apoptosis in monocytic cells. OxLDL at 25-50 mug/ml inhibited staurosporine-induced apoptosis in THP-1 cells ... | ['Apoptosis', 'Caspases', 'Cell Line', 'Cells, Cultured', 'Cytochromes c', 'Extracellular Signal-Regulated MAP Kinases', 'Humans', 'Lipoproteins, LDL', 'MAP Kinase Signaling System', 'Macrophages, Peritoneal', 'Monocytes', 'Myeloid Cell Leukemia Sequence 1 Protein', 'Neoplasm Proteins', 'Proto-Oncogene Proteins c-bcl-2... | 17,890,680 | [['G04.146.954.035'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['A11.251.210'], ['A11.251'], ['D08.244.286.100', 'D12.776.422.220.286.100'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['B01.050.150.900.649.3... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dark H2 fermentation from sucrose and xylose using H2-producing indigenous bacteria: feasibility and kinetic studies. | Cellulosic materials are the major components in biomass feedstock used for bioenergy production. Hydrolytic products of cellulosic substances consist primarily of hexose (e.g., glucose) and pentose (e.g., xylose). In this study, the efficiency of fermentative conversion of sucrose (representing hexose) and xylose into... | ['Base Sequence', 'Bioreactors', 'Clostridium', 'DNA, Bacterial', 'Feasibility Studies', 'Fermentation', 'Hydrogen', 'Kinetics', 'Klebsiella', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Sucrose', 'Xylose'] | 17,889,245 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E07.115', 'J01.897.120.115'], ['B03.300.390.400.200', 'B03.353.625.375.500', 'B03.510.415.400.200'], ['D13.444.308.212'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['G02.111.158.249', 'G03.191.249'], ['D01.268.406', 'D... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Selenium renal homeostasis is impaired in patients receiving long-term total parenteral nutrition. | Selenium deficiency has been reported previously in patients receiving long-term total parenteral nutrition (TPN) without selenium supplementation in their solutions. The recommended dietary allowance for selenium is 0.87 microgram/kg, of which 80% is absorbed. We studied 28 adult long-term TPN patients aged 21 to 79 y... | ['Adult', 'Aged', 'Female', 'Glomerular Filtration Rate', 'Homeostasis', 'Humans', 'Kidney', 'Male', 'Middle Aged', 'Parenteral Nutrition, Total', 'Selenium'] | 8,064,998 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.390.400.300', 'G08.852.357'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['M01.060.116.630'], ['E02.421.505.575', 'E02.642.500.505.750'], ['D01.268.185.850', 'D01.578.700']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Older women: victims of rape. | Older female rape victims usually live alone, are raped by strangers, experience physical force and injury, and also are robbed. Rape trauma syndrome, a nursing diagnosis, consists of an acute phase of disorganization, and a long-term phase of reorganization of the victim's lifestyle. Rape victims experience emotional,... | ['Aged', 'Female', 'Humans', 'Middle Aged', 'Nursing Diagnosis', 'Rape', 'Stress Disorders, Post-Traumatic'] | 8,491,962 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N04.590.233.508.480.110'], ['I01.198.240.748.640', 'I01.198.240.856.744', 'I01.880.735.900.772'], ['F03.950.750.500']] | ['Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Hydrochemical characteristics and quality assessment of groundwater from fractured Albian carbonaceous shale aquifers around Enyigba-Ameri, southeastern Nigeria. | Enyigba-Ameri area is known for its Pb-Zn mining activities and the mine water is usually discharged directly into nearby streams and surface runoff. In order to determine the impacts of mining activities on the quality of water in the area and the general hydrochemical characteristics, field measurements and laborator... | ['Agricultural Irrigation', 'Carbonates', 'Environmental Monitoring', 'Groundwater', 'Ion Exchange', 'Metals, Heavy', 'Minerals', 'Mining', 'Nigeria', 'Water Pollutants, Chemical', 'Water Quality'] | 30,715,614 | [['J01.040.044'], ['D01.045.125', 'D01.200.275.150', 'D01.248.497.158.165'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.355'], ['G02.437'], ['D01.268.556', 'D01.552.544'], ['D01.578'], ['J01.576.655.875.500'], ['Z01.058.290.190.565'], ['D27.888.284.903.655'], ['N06.850.460.350.080.750', 'N06.850.460.790.730'... | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
PD-L1 and PD-L2 Are Differentially Expressed by Macrophages or Tumor Cells in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type. | As checkpoint molecules' inhibition may represent a therapeutic option in relapsing cases, we assessed programmed death ligands' (PD-L1/PD-L2) expression in a series of 29 primary cutaneous diffuse large B-cell lymphoma, leg-type (PCDLBCL-LT) cases. Double immunostaining for either PD-L1 or PD-L2 was associated either ... | ['Aged', 'Aged, 80 and over', 'Antigens, CD', 'Antigens, Differentiation, Myelomonocytic', 'B7-H1 Antigen', 'Biomarkers, Tumor', 'Female', 'Gene Rearrangement', 'Genetic Loci', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization, Fluorescence', 'Leg', 'Lymphocytes, Tumor-Infiltrating', 'Lymphoma, Large B-Cell, Dif... | 29,112,015 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.900', 'D23.101.100.900'], ['D12.776.465.625', 'D12.776.467.150.300', 'D12.776.543.095.300', 'D23.050.301.285.400', 'D23.529.168.300'], ['D23.101.140'], ['G05.344'], ['G05.360.340.024.380'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of purmorphamine on osteoblast phenotype expression of human bone marrow mesenchymal cells cultured on titanium. | Purmorphamine is a new molecule with osteogenesis-inducing activity in multipotent progenitor cells. The aim of this study was to evaluate whether purmorphamine maintains its osteogenic potential on human bone marrow mesenchymal cells cultured on commercially pure titanium (cpTi). Cells were cultured either in the abse... | ['Bone Marrow Cells', 'Cell Differentiation', 'Cell Proliferation', 'Cell Survival', 'Cells, Cultured', 'Coated Materials, Biocompatible', 'Humans', 'Materials Testing', 'Mesenchymal Stem Cells', 'Morpholines', 'Osseointegration', 'Osteoblasts', 'Purines', 'Titanium'] | 15,683,647 | [['A11.148', 'A15.378.316'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.251'], ['D25.130.420', 'J01.637.051.130.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['A11.329.830.500', 'A11.872.590.500'], ['D03.383.533.640'], ['G11.427.213.140.570', 'G16.762.150.150.570'], [... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pulmonary vascular abnormalities in chronic obstructive pulmonary disease undergoing lung transplant. | BACKGROUND: Little is known about the structure and function relationships of pulmonary vessels in the most severe chronic obstructive pulmonary disease (COPD) spectrum. We investigated morphometric, cellular, and physiologic characteristics of pulmonary arteries from COPD patients undergoing bilateral lung transplant.... | ['CD8-Positive T-Lymphocytes', 'Female', 'Humans', 'Hypertension, Pulmonary', 'Lung', 'Lung Transplantation', 'Male', 'Middle Aged', 'Pulmonary Artery', 'Pulmonary Disease, Chronic Obstructive', 'Pulmonary Emphysema', 'Retrospective Studies', 'Vascular Resistance', 'Vasoconstriction'] | 24,263,025 | [['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['A04.411'], ['E04.928.600.495', 'E04.936.450.495'], ['M01.060.116.630'], ['A07.015.114.715'], ['C08.381.495.389'], ['C08.381.495.389.7... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Co-prevalence of carotid stenosis and coronary artery disease in Chinese patients with paroxysmal atrial fibrillation. | OBJECTIVES: To investigate the co-prevalence of coronary artery disease (CAD) and carotid stenosis and to determine predictors related to CAD in Chinese patients with paroxysmal atrial fibrillation (PAF), presenting without previously diagnosed or excluded CAD.METHODS: Consecutive patients with PAF were recruited. CAD ... | ['Aged', 'Aged, 80 and over', 'Asian Continental Ancestry Group', 'Atrial Fibrillation', 'Carotid Arteries', 'Carotid Intima-Media Thickness', 'Carotid Stenosis', 'China', 'Coronary Artery Disease', 'Diabetes Mellitus', 'Female', 'Humans', 'Hyperhomocysteinemia', 'Male', 'Middle Aged', 'Risk Factors'] | 25,231,437 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200'], ['C14.280.067.198', 'C23.550.073.198'], ['A07.015.114.186'], ['E01.370.350.850.150', 'E01.370.370.180', 'G09.330.210'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['Z01.252.474.164'], ['C14.280.647.250.260', 'C14.907.137.126... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Chronic effects of venlafaxine on synaptophysin and neuronal cell adhesion molecule in the hippocampus of cerebral ischemic mice. | Venlafaxine, a novel antidepressant, inhibits serontonin and norepinephrine reuptake in the presynaptic cleft. Unlike typical selective serontonin reuptake inhibitors (SSRIs), venlafaxine may have modulatory effects on nerve terminals and neuronal plasticity. Our preliminary data found that 5 mg.kg-1.d-1 of venlafaxine... | ['Animals', 'Antidepressive Agents, Second-Generation', 'Brain Ischemia', 'Cyclohexanols', 'Depressive Disorder', 'Dose-Response Relationship, Drug', 'Drug Evaluation, Preclinical', 'Hippocampus', 'Male', 'Mice', 'Neural Cell Adhesion Molecule L1', 'Neuronal Plasticity', 'Serotonin Uptake Inhibitors', 'Synaptophysin', ... | 20,651,837 | [['B01.050'], ['D27.505.954.427.700.122.050'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['F03.600.300'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.750', 'E05.337.550'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Osmotic water transport with glucose in GLUT2 and SGLT. | Carrier-mediated water cotransport is currently a favored explanation for water movement against an osmotic gradient. The vestibule within the central pore of Na(+)-dependent cotransporters or GLUT2 provides the necessary precondition for an osmotic mechanism, explaining this phenomenon without carriers. Simulating equ... | ['Computer Simulation', 'Diffusion', 'Glucose', 'Glucose Transporter Type 2', 'Models, Chemical', 'Models, Molecular', 'Osmotic Pressure', 'Pressure', 'Protein Conformation', 'Sodium-Glucose Transport Proteins', 'Water'] | 18,234,816 | [['L01.224.160'], ['G01.202', 'G02.196'], ['D09.947.875.359.448'], ['D12.776.157.530.500.500.750', 'D12.776.157.530.937.563.750', 'D12.776.543.585.500.500.750', 'D12.776.543.585.937.625.750'], ['E05.599.495'], ['E05.599.595'], ['G01.374.715.578', 'G02.640.249', 'G02.723.661'], ['G01.374.715'], ['G02.111.570.820.709'], ... | ['Information Science [L]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Expression of basement membrane antigens in spindle cell melanoma. | Spindle cell melanoma (SCM) is an uncommon form of melanoma that may be confused histologically with other tumors, including malignant peripheral nerve sheath tumors (MPNST). Tumors with neural differentiation and melanocytic nevi may both show basement membrane immunohistochemically and at the ultrastructural level. H... | ['Antigens, Neoplasm', 'Collagen', 'Humans', 'Immunoenzyme Techniques', 'Laminin', 'Melanoma', 'Melanoma-Specific Antigens', 'Middle Aged', 'Neoplasm Proteins', 'S100 Proteins', 'Skin Neoplasms'] | 9,694,618 | [['D23.050.285'], ['D05.750.078.280', 'D12.776.860.300.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['D12.776.395.550.530', 'D12.776.543.550.500', 'D12.776.860.300.675'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Living apart together-bacterial volatiles influence methanotrophic growth and activity. | Volatile organic compounds play an important role in microbial interactions. However, little is known about how volatile-mediated interactions modulate biogeochemical processes. In this study, we show the effect of volatile-mediated interaction on growth and functioning of aerobic methane-oxidizing bacteria, grown in c... | ['Heterotrophic Processes', 'Methane', 'Methylococcaceae', 'Methylocystaceae', 'Pseudomonas', 'Volatile Organic Compounds'] | 29,382,947 | [['G02.111.375', 'G03.393'], ['D02.455.326.146.571'], ['B03.440.400.425.500', 'B03.660.250.500'], ['B03.660.050.512'], ['B03.440.400.425.625.625', 'B03.660.250.580.590'], ['D02.974']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stratified multivariate analysis of prognostic markers in breast cancer: a preliminary report. | Published results using prognostic markers in breast cancer have been very confusing to oncologists, surgeons, and pathologists alike. As a result, there is a wide variation in opinion among oncologists about the utility of these markers in clinical practice. This study was undertaken to determine the utility of strati... | ['Adult', 'Aged', 'Breast Neoplasms', 'Female', 'Humans', 'Lymphatic Metastasis', 'Middle Aged', 'Multivariate Analysis', 'Prognosis', 'Receptors, Estrogen'] | 9,137,503 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E01.789'], ['D12.776.826.750.350', 'D12.776.930.77... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A Boltzmann filter improves the prediction of RNA folding pathways in a massively parallel genetic algorithm. | RNA folding using the massively parallel genetic algorithm (GA) has been enhanced by the addition of a Boltzmann filter. The filter uses the Boltzmann probability distribution in conjunction with Metropolis' relaxation algorithm. The combination of these two concepts within the GA's massively parallel computational env... | ['Algorithms', 'Models, Genetic', 'Nucleic Acid Conformation', 'Probability', 'RNA', 'RNA, Ribosomal, 16S', 'Solutions', 'Thermodynamics'] | 10,636,092 | [['G17.035', 'L01.224.050'], ['E05.599.395.397'], ['G02.111.570.820.486', 'G05.360.580'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['D13.444.735'], ['D13.444.735.686.670'], ['D26.776'], ['G01.906']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
In vitro effect of myo-inositol on sperm motility in normal and oligoasthenospermia patients undergoing in vitro fertilization. | It is a known fact that abnormal seminal liquid specimens contain abnormal amounts of oxygen free radicals and reactive oxygen species (ROS), and that the use of antioxidant molecules both in vivo and in vitro leads to improvement of semen quality in terms of motility, reduction in DNA damage, with obvious consequences... | ['Adult', 'Asthenozoospermia', 'Fertilization in Vitro', 'Humans', 'Inositol', 'Male', 'Oligospermia', 'Sperm Motility', 'Vitamin B Complex'] | 27,908,215 | [['M01.060.116'], ['C12.294.365.700.253'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.800.519', 'D09.853.519'], ['C12.294.365.700.508'], ['E01.370.225.992.812', 'E05.200.992.812', 'G04.198.750'], ['D27.505.696.494.600.708']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Is routine postoperative nasogastric decompression really necessary? | Controversy exists regarding the need for nasogastric tube decompression and the incidence of complications resulting from its use following major intra-abdominal surgery. To determine the value of such tubes, 100 patients were managed after surgery with a nasogastric tube in situ until the passage of flatus per rectum... | ['Cholecystectomy', 'Colostomy', 'Decompression', 'Digestive System Surgical Procedures', 'Humans', 'Ileostomy', 'Intubation, Gastrointestinal', 'Nose', 'Postoperative Care'] | 3,970,606 | [['E04.210.120.172'], ['E04.210.338.225', 'E04.579.338.225'], ['E02.278', 'G01.374.715.250'], ['E04.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.508', 'E04.579.338.508'], ['E02.585.412', 'E05.497.412'], ['A01.456.505.733', 'A04.531', 'A09.531'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The mechanisms of morphological-motor functioning in elementary school female first- to fourth-graders. | Four morphological and 7 motor variables were assessed in a sample of 2,235 female children (subdivided into 4 groups) aged 7-11 years, elementary school first- to fourth-graders from the Primorje-Gorski Kotar County, Republic of Croatia. The study objective was to analyze the morphological-motor structures according t... | ['Age Factors', 'Child', 'Child Development', 'Croatia', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Motor Skills', 'Somatotypes'] | 15,636,082 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['Z01.542.248.295'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808.260'], ['E01.370.600.115.800', 'G07.100.800']] | ['Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Stimulus complexity in reminiscence therapy and scores on the Beck Depression Inventory of a small group of nursing-home residents. | A pilot study of the efficacy of groups given single and multistimulus reminiscence therapy versus no treatment controls gave no significant effect in reducing depression in 12 nursing-home residents 68.5 yr. of age. However, the data indicate that effectiveness of treatment was likely attenuated by including participa... | ['Aged', 'Attention', 'Confusion', 'Depression', 'Female', 'Frail Elderly', 'Homes for the Aged', 'Humans', 'Life Change Events', 'Male', 'Mental Recall', 'Nursing Homes', 'Personality Inventory', 'Pilot Projects', 'Psychotherapy', 'Reality Testing', 'Socialization'] | 8,774,040 | [['M01.060.116.100'], ['F02.830.104.214'], ['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['F01.145.126.350'], ['M01.060.116.100.540'], ['J03.775.462', 'N02.278.825.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['F02.463.425.540.641'], ['N02.278.825.610'], ['F04.711.647.513'],... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
[Family environment and attention-deficit hyperactivity disorder]. | OBJECTIVE: To analyze factors associated with attention-deficit and hyperactivity disorder in children.METHODS: This is a longitudinal study about behavior problems in schoolchildren that was carried out in the city of S?o Gon?alo (Southeastern Brazil) in 2005. A total of 479 students from public schools was analyzed, ... | ['Adolescent', 'Age Factors', 'Attention Deficit Disorder with Hyperactivity', 'Brazil', 'Child', 'Child Behavior Disorders', 'Domestic Violence', 'Family Relations', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Prevalence', 'Public Sector', 'Schools', 'Socioeconomic Factors', 'Students', 'Wechsler Scales'] | 22,735,270 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['F03.625.094.150'], ['Z01.107.757.176'], ['M01.060.406'], ['F03.625.141'], ['I01.198.240.856.350', 'I01.880.735.900.350'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-x(L). | Transient gene expression (TGE) provides a method for quickly delivering protein for research using mammalian cells. While high levels of recombinant proteins have been produced in TGE experiments in HEK 293 cells, TGE efforts in the commercially prominent CHO cell line still suffer from inadequate protein yields. Here... | ['Animals', 'Apoptosis', 'CHO Cells', 'Cell Survival', 'Cricetinae', 'Cricetulus', 'Gene Expression', 'Recombinant Fusion Proteins', 'Transfection', 'bcl-X Protein'] | 18,727,128 | [['B01.050'], ['G04.146.954.035'], ['A11.251.210.200', 'A11.436.155'], ['G04.346'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['G05.297'], ['D12.776.828.300'], ['E05.393.350.810', 'G05.728.860'], ['D12.644.360.075.718.937', 'D12.776.476.075.718.875']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optical properties and chemical behavior of Laser-dye Coumarin-500 and the influence of atmospheric corona discharges. | Structure elucidation of Coumarin-500 Laser-dye in cyclohexane at room temperature has been studied by UV-Vis, Raman, and FTIR spectroscopic techniques. Optical properties and chemical behavior under the influence of atmospheric positive electric pulsed corona discharges were also examined. The effects of UV-Vis irradi... | ['Atmosphere', 'Coloring Agents', 'Coumarins', 'Electrochemical Techniques', 'Lasers', 'Molecular Structure', 'Optics and Photonics', 'Photochemistry', 'Spectrum Analysis'] | 19,038,576 | [['G16.500.275.063', 'N06.230.300.100'], ['D27.720.233'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['E05.301'], ['E07.632.490', 'E07.710.520'], ['G02.111.570', 'G02.466'], ['H01.671.617', 'J01.293.688'], ['H01.181.529.711'], ['E05.196.867']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Basket-like interneurones in layer II of the entorhinal cortex exhibit a powerful NMDA-mediated synaptic excitation. | Spiny stellate neurones of layer II of the entorhinal cortex (EC) provide the perforant path input to the dentate gyrus. Previous studies have shown that synaptic responses of these neurones are dominated by GABAergic inhibition. The present study describes intracellular recordings from 'fast-spiking' interneurones in ... | ['Animals', 'Electric Stimulation', 'Electrophysiology', 'Fluorescent Dyes', 'Interneurons', 'Isoquinolines', 'Limbic System', 'N-Methylaspartate', 'Rats', 'Rats, Wistar', 'Reaction Time', 'Synapses'] | 8,469,376 | [['B01.050'], ['E05.723.402'], ['H01.158.344.528', 'H01.158.782.236'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A08.675.358', 'A11.671.358'], ['D03.633.100.531'], ['A08.186.211.180'], ['D12.125.067.500.400', 'D12.125.119.170.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Study on intravascular pressure change during sclerotherapy for cavernous hemangiomas (CHs)]. | To investigate the regulation and significance of the intravascular pressure change of cavernous hemangiomas during the treatment of sclerotherapy, we did observations in 29 cases with slowing down the efferent blood flow of the CHs in their treatment. It was found that the baseline intravascular pressure of CHs is 5-1... | ['Adolescent', 'Adult', 'Blood Pressure', 'Child', 'Child, Preschool', 'Diatrizoate Meglumine', 'Female', 'Hemangioma, Cavernous', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Sclerosing Solutions', 'Sclerotherapy'] | 10,451,992 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['M01.060.406'], ['M01.060.406.448'], ['D02.033.800.813.550.500', 'D02.241.223.100.400.880.270.500', 'D02.455.426.559.389.127.375.880.270.500', 'D09.067.342.600.500', 'D09.853.813.550.500'], ['C04.557.645.375.385', 'C14.907.454.385', 'C15.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Hygienic principles of the optimal arrangement of working place for students during the training in computer use]. | Experimental studies aimed at hygienic substantiation of requirements for optimal organization of a workplace for schoolchildren using computers have been carried out. Hygienic requirements for basic parameters and design of a desk and a chair intended for those working with computers are presented. Practical recommend... | ['Adolescent', 'Arm', 'Child', 'Computer Systems', 'Computer User Training', 'Equipment Design', 'Facility Design and Construction', 'Humans', 'Muscles', 'Psychomotor Performance', 'Students', 'USSR'] | 2,384,232 | [['M01.060.057'], ['A01.378.800.075'], ['M01.060.406'], ['L01.224.230'], ['I02.903.080'], ['E05.320'], ['J01.086.339', 'N02.278.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633', 'A10.690'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['M01.848'], ['Z01.542.931', 'Z01.586.950']] | ['Named Groups [M]', 'Anatomy [A]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenom... | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
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